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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Panaxynol
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Accession:CHEBI:66722 term browser browse the term
Definition:A long-chain fatty alcohol that has formula C17H24O.
Synonyms:related_synonym: (3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol;   (3R,9Z)-heptadeca-1,9-dien-4,6-diyn-3-ol;   Carotatoxin;   Falcarinol;   Formula=C17H24O;   InChI=1S/C17H24O/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17(18)4-2/h4,10-11,17-18H,2-3,5-9,12H2,1H3/b11-10-/t17-/m1/s1;   InChIKey=UGJAEDFOKNAMQD-QXPKXGMISA-N;   SMILES=CCCCCCC\\C=C/CC#CC#C[C@H](O)C=C
 xref: CAS:21852-80-2;   KEGG:C08450;   KNApSAcK:C00001284
 xref_mesh: MESH:C018541
 xref: PMID:2092947;   PMID:21417387;   PMID:21800857;   PMID:9987830



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Panaxynol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator decreases expression EXP falcarinol results in decreased expression of BAX protein CTD PMID:19800326 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP falcarinol results in increased expression of BCL2 protein CTD PMID:19800326 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
EXP falcarinol results in decreased expression of and results in decreased activity of CASP3 protein
falcarinol results in decreased expression of CASP3 protein modified form
CTD PMID:19800326 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of CREB1 protein] CTD PMID:18199429 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression EXP falcarinol results in increased expression of HIF1A protein CTD PMID:19800326 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein] CTD PMID:18199429 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18199429 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of CREB1 protein]; falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18199429 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19763
      biological role 19763
        biochemical role 19380
          metabolite 19358
            Panaxynol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      chalcogen 19460
                        oxygen atom 19436
                          oxygen molecular entity 19436
                            hydroxides 19169
                              organic hydroxy compound 18662
                                alcohol 15089
                                  fatty alcohol 5981
                                    long-chain fatty alcohol 31
                                      Panaxynol 8
paths to the root