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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Panaxynol
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Accession:CHEBI:66722 term browser browse the term
Definition:A long-chain fatty alcohol that has formula C17H24O.
Synonyms:related_synonym: (3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol;   (3R,9Z)-heptadeca-1,9-dien-4,6-diyn-3-ol;   Carotatoxin;   Falcarinol;   Formula=C17H24O;   InChI=1S/C17H24O/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17(18)4-2/h4,10-11,17-18H,2-3,5-9,12H2,1H3/b11-10-/t17-/m1/s1;   InChIKey=UGJAEDFOKNAMQD-QXPKXGMISA-N;   SMILES=CCCCCCC\\C=C/CC#CC#C[C@H](O)C=C
 xref: CAS:21852-80-2;   KEGG:C08450;   KNApSAcK:C00001284
 xref_mesh: MESH:C018541
 xref: PMID:2092947;   PMID:21417387;   PMID:21800857;   PMID:9987830



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Panaxynol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator decreases expression EXP falcarinol results in decreased expression of BAX protein CTD PMID:19800326 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP falcarinol results in increased expression of BCL2 protein CTD PMID:19800326 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
EXP falcarinol results in decreased expression of and results in decreased activity of CASP3 protein
falcarinol results in decreased expression of CASP3 protein modified form
CTD PMID:19800326 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of CREB1 protein] CTD PMID:18199429 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression EXP falcarinol results in increased expression of HIF1A protein CTD PMID:19800326 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein] CTD PMID:18199429 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18199429 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of CREB1 protein]; falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; falcarinol inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:18199429 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            Panaxynol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        monocarboxylic acid 17984
                                          fatty acid 16709
                                            fatty acid derivative 8927
                                              fatty alcohol 6041
                                                long-chain fatty alcohol 34
                                                  Panaxynol 8
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