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Term:6-methoxyspirotryprostatin B
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Accession:CHEBI:66707 term browser browse the term
Definition:An indole alkaloid isolated from a marine-derived fungal strain Aspergillus sydowii PFW1-13 and has been shown to exhibit cytotoxic activity.
Synonyms:exact_synonym: (2S,3S,5aS)-6'-methoxy-3-(2-methylprop-1-en-1-yl)-5a,6,7,8-tetrahydro-5H,10H-spiro[dipyrrolo[1,2-a:1',2'-d]pyrazine-2,3'-indole]-2',5,10(1'H)-trione
 related_synonym: Formula=C22H23N3O4;   InChI=1S/C22H23N3O4/c1-12(2)9-18-22(14-7-6-13(29-3)10-15(14)23-21(22)28)11-17-19(26)24-8-4-5-16(24)20(27)25(17)18/h6-7,9-11,16,18H,4-5,8H2,1-3H3,(H,23,28)/t16-,18-,22-/m0/s1;   InChIKey=UHQKDPCPFNXIDU-ZJBJCVSYSA-N;   SMILES=[H][C@@]12CCCN1C(=O)C1=C[C@]3([C@H](C=C(C)C)N1C2=O)C(=O)Nc1cc(OC)ccc31
 xref: Chemspider:23329453;   PMID:18505285 "Europe PMC";   Reaxys:18842463 "Reaxys"

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  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            antineoplastic agent 16555
              6-methoxyspirotryprostatin B 0
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  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  organic heteropolycyclic compound 17423
                                    organic heterobicyclic compound 15889
                                      benzopyrrole 5747
                                        indoles 5526
                                          indolones 188
                                            6-methoxyspirotryprostatin B 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.