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Accession:CHEBI:66666 term browser browse the term
Definition:A sesterterpenoid isolated from the marine sponge Luffariella variabilis and which has been shown to exhibit inhibitory activity towards phospholipase A2.
Synonyms:exact_synonym: (5R)-5-hydroxy-4-{(2R,6R)-6-hydroxy-5-[(3E)-4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hex-3-en-1-yl]-3,6-dihydro-2H-pyran-2-yl}furan-2(5H)-one
 related_synonym: Formula=C25H36O5;   InChI=1S/C25H36O5/c1-16(10-12-20-17(2)8-6-14-25(20,3)4)7-5-9-18-11-13-21(29-23(18)27)19-15-22(26)30-24(19)28/h7,11,15,21,23-24,27-28H,5-6,8-10,12-14H2,1-4H3/b16-7+/t21-,23-,24-/m1/s1;   InChIKey=FGJIDQWRRLDGDB-CPIXEKRISA-N;   SMILES=C\\C(CCC1=C(C)CCCC1(C)C)=C/CCC1=CC[C@@H](O[C@H]1O)C1=CC(=O)O[C@H]1O
 xref: CAS:75088-80-1 "ChemIDplus";   KEGG:C17156;   LIPID_MAPS_instance:LMPR0105020001 "LIPID MAPS"
 xref_mesh: MESH:C045673
 xref: PMID:10101221 "Europe PMC";   PMID:10437157 "Europe PMC";   PMID:22394195 "Europe PMC";   PMID:25584012 "Europe PMC";   PMID:2586492 "Europe PMC";   PMID:3997864 "Europe PMC";   PMID:8149454 "Europe PMC";   Patent:CA1297030;   Patent:US4839385;   Reaxys:10729444 "Reaxys";   Wikipedia:Manoalide

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manoalide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        biochemical role 19130
          metabolite 19098
            manoalide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic group 18338
                              organic divalent group 18329
                                organodiyl group 18329
                                  carbonyl group 18218
                                    carbonyl compound 18218
                                      carboxylic ester 13930
                                        lactone 5862
                                          gamma-lactone 1196
                                            butenolide 338
                                              manoalide 3
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.