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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lucidenic acid N
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Accession:CHEBI:66595 term browser browse the term
Definition:A tetracyclic triterpenoid that is 25,26,27-trinorlanost-8-en-24-oic acid substituted by hydroxy groups at positions 3 and 7 and oxo groups at positions 11 and 15 respectively (the 3beta,5alpha,7beta stereoisomer). Isolated from the fruiting bodies of Ganoderma lucidum, it exhibits cytotoxicity against tumour cells.
Synonyms:exact_synonym: (3beta,5alpha,7beta)-3,7-dihydroxy-4,4,14-trimethyl-11,15-dioxochol-8-en-24-oic acid
 related_synonym: 3,7-Dihydroxy-25,26,27-trinor-11,15-dioxolanost-8-en-24-oic acid;   Formula=C27H40O6;   InChI=1S/C27H40O6/c1-14(7-8-21(32)33)15-11-20(31)27(6)23-16(28)12-18-24(2,3)19(30)9-10-25(18,4)22(23)17(29)13-26(15,27)5/h14-16,18-19,28,30H,7-13H2,1-6H3,(H,32,33)/t14-,15-,16+,18+,19+,25+,26-,27+/m1/s1;   InChIKey=YBGBNHHXOJXFNM-UQCMLMITSA-N;   SMILES=[H][C@@]1(CC(=O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])C[C@@H]3O)[C@H](C)CCC(O)=O
 xref: Chemspider:10213993;   HMDB:HMDB0038352
 xref_mesh: MESH:C437028
 xref: PMID:11520245;   PMID:18422750;   PMID:21924611;   Reaxys:8956644



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lucidenic acid N term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO lucidenic acid N analog results in increased expression of HMOX1 protein CTD PMID:25239868 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19730
    role 19703
      biological role 19701
        biochemical role 19414
          metabolite 19400
            lucidenic acid N 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19730
    subatomic particle 19728
      composite particle 19728
        hadron 19728
          baryon 19728
            nucleon 19728
              atomic nucleus 19728
                atom 19728
                  main group element atom 19676
                    p-block element atom 19676
                      carbon group element atom 19620
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18827
                              organic divalent group 18812
                                organodiyl group 18812
                                  carbonyl group 18778
                                    carbonyl compound 18778
                                      carboxylic acid 18499
                                        monocarboxylic acid 17830
                                          oxo monocarboxylic acid 6281
                                            dioxo monocarboxylic acid 1911
                                              lucidenic acid N 1
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