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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:malathion
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Accession:CHEBI:6651 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Synonyms:exact_synonym: rac-diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
 related_synonym: Karbofos;   Maldison;   O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl);   O,O-dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate;   O,O-dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate;   O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl;   O,O-dimethyldithiophosphate diethylmercaptosuccinate;   [(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester;   carbophos;   diethyl ((dimethoxyphosphinothioyl)thio)butanedioate;   diethyl (dimethoxyphosphinothioylthio)succinate;   diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate;   mercaptothion
 xref: Beilstein:1804525;   CAS:121-75-5;   DrugBank:DB00772;   Drug_Central:1626;   KEGG:C07497;   KEGG:D00534
 xref_mesh: MESH:D008294
 xref: PMID:16083681;   PMID:19399610;   PMID:28950791;   PMID:29235025;   PMID:29792547;   PMID:29852369;   Reaxys:1804525;   Wikipedia:Malathion


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malathion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
[Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Malathion results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Malathion results in decreased activity of ACHE protein]
[Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein; [Malathion co-treated with Permethrin] results in increased activity of ACHE protein; Taurine inhibits the reaction [Malathion results in decreased activity of ACHE protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of ACHE protein]
CTD PMID:2380476, PMID:4859365, PMID:14713564, PMID:18617161, PMID:19429256, PMID:19784758, PMID:21628957, PMID:21723318, PMID:21983245, PMID:23774768, PMID:28987951, PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression ISO Malathion results in decreased expression of ACSM1 mRNA CTD PMID:17311802 NCBI chr 1:189,359,374...189,395,277
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Add3 adducin 3 increases expression EXP Malathion results in increased expression of ADD3 mRNA CTD PMID:19784758 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Aff1 AF4/FMR2 family, member 1 increases expression ISO Malathion results in increased expression of AFF1 mRNA mutant form CTD PMID:28624474 NCBI chr14:7,222,883...7,384,916
Ensembl chr14:7,226,586...7,384,876
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [prothioconazole co-treated with terbutylazine co-treated with bitertanol co-treated with cypermethrin co-treated with Malathion] results in increased activity of AHR protein CTD PMID:25684042 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Malathion results in increased expression of AKR1C2 mRNA CTD PMID:16079077 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Ar androgen receptor multiple interactions ISO [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; [terbutylazine co-treated with bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion] results in decreased activity of AR protein CTD PMID:23871939 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 decreases expression ISO Malathion results in decreased expression of B4GALT1 mRNA CTD PMID:32069766 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions
EXP
ISO
Malathion results in decreased expression of BAX mRNA
Malathion results in increased expression of BAX protein
Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein]
CTD PMID:23774768, PMID:30769050 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity
decreases activity
ISO
EXP
Obidoxime Chloride inhibits the reaction [Malathion results in decreased activity of BCHE protein]
Malathion results in increased activity of BCHE protein
CTD PMID:17364237, PMID:18617161, PMID:21983245, PMID:25180440 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
EXP
ISO
Malathion results in decreased expression of BCL2 mRNA
Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein]
CTD PMID:23774768, PMID:30769050 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger increases expression ISO Malathion results in increased expression of BMI1 mRNA CTD PMID:32069766 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Brd7 bromodomain containing 7 increases expression ISO Malathion results in increased expression of BRD7 mRNA CTD PMID:18214912 NCBI chr19:19,672,780...19,701,484
Ensembl chr19:19,672,856...19,701,484
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO Malathion results in decreased expression of BTG1 mRNA CTD PMID:32069766 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Malathion results in decreased expression of BUB1 mRNA CTD PMID:16079077 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA] CTD PMID:28385489 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Malathion results in increased activity of CASP3 protein
Malathion results in increased activity of and results in increased cleavage of CASP3 protein; Metoclopramide inhibits the reaction [Malathion results in increased activity of and results in increased cleavage of CASP3 protein]
Malathion results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]
Malathion results in increased expression of CASP3 mRNA
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]
CTD PMID:12505448, PMID:19815060, PMID:21628957, PMID:29027213, PMID:30769050 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 decreases expression ISO Malathion results in decreased expression of CASP4 mRNA CTD PMID:32069766 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp8 caspase 8 increases activity ISO Malathion results in increased activity of CASP8 protein CTD PMID:12505448 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
multiple interactions
increases expression
ISO
EXP
Malathion results in increased activity of CASP9 protein
Malathion results in increased cleavage of CASP9 protein
Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]
CTD PMID:12505448, PMID:21628957, PMID:30769050 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
increases activity
EXP
ISO
[Dimethoate co-treated with Malathion] results in increased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of CAT protein]; Pentoxifylline inhibits the reaction [Malathion results in increased activity of CAT protein]; Taurine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]; zinc chloride inhibits the reaction [Malathion results in decreased activity of CAT protein]
Malathion results in decreased expression of CAT protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Vitamin E inhibits the reaction [Malathion results in increased activity of CAT protein]
[Malathion co-treated with 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide] results in increased activity of CAT protein; [Malathion co-treated with pralidoxime] results in increased activity of CAT protein; lavender oil inhibits the reaction [Malathion results in decreased expression of CAT protein]
CTD PMID:11834209, PMID:18655177, PMID:19429256, PMID:20194575, PMID:21628957, PMID:21723318, PMID:24810974, PMID:25180440, PMID:28987951, PMID:30409133, PMID:30769050 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbfb core-binding factor subunit beta increases expression ISO Malathion results in increased expression of CBFB mRNA CTD PMID:32069766 NCBI chr19:37,127,508...37,171,075
Ensembl chr19:37,127,508...37,171,069
JBrowse link
G Cck cholecystokinin increases expression EXP Malathion results in increased expression of CCK mRNA CTD PMID:19784758 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Malathion results in decreased expression of CCNA2 protein CTD PMID:30769050 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Malathion results in decreased expression of CCNB1 protein CTD PMID:30769050 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Malathion results in decreased expression of CCNE1 protein CTD PMID:30769050 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Malathion results in decreased expression of CD14 mRNA CTD PMID:32069766 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd36 CD36 molecule increases expression ISO Malathion results in increased expression of CD36 mRNA CTD PMID:32069766 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd5 Cd5 molecule decreases expression ISO Malathion results in decreased expression of CD5 mRNA CTD PMID:32069766 NCBI chr 1:226,770,912...226,791,861
Ensembl chr 1:226,770,744...226,791,879
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Malathion results in decreased expression of CDC20 mRNA CTD PMID:18214805 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
increases expression
ISO Malathion results in decreased expression of CDK2 protein
Malathion results in increased expression of CDK2 mRNA
CTD PMID:30769050, PMID:32069766 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO Malathion results in increased expression of CEBPG mRNA CTD PMID:32069766 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Cenpf centromere protein F decreases expression ISO Malathion results in decreased expression of CENPF mRNA CTD PMID:16079077 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Malathion results in increased expression of CES1 mRNA CTD PMID:17311802 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cldn5 claudin 5 multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of CLDN5 protein
Malathion results in decreased expression of CLDN5 protein
CTD PMID:20970449 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO Malathion results in increased expression of COL1A2 mRNA CTD PMID:32069766 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
decreases expression
EXP caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:20233601, PMID:25404496 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 decreases expression EXP Malathion results in decreased expression of CRISPLD2 mRNA CTD PMID:19784758 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Ctsd cathepsin D increases expression ISO Malathion results in increased expression of CTSD protein CTD PMID:8812242 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO Malathion results in decreased expression of CYP11A1 mRNA
lavender oil inhibits the reaction [Malathion results in decreased expression of CYP11A1 mRNA]
CTD PMID:30409133 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions EXP [bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA CTD PMID:23954766 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
increases expression
ISO CYP1A2 protein affects the metabolism of Malathion
Malathion results in increased expression of CYP1A2 mRNA
CTD PMID:15557345, PMID:22310298 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects metabolic processing
multiple interactions
increases expression
decreases activity
ISO CYP2B6 protein affects the metabolism of Malathion
Malathion promotes the reaction [isomalathion results in increased expression of CYP2B6 mRNA]
Malathion results in increased expression of CYP2B6 mRNA
Malathion results in decreased activity of CYP2B6 protein
CTD PMID:15557345, PMID:22310298, PMID:24333466 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
ISO Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]
Malathion results in decreased activity of CYP2E1 protein
CTD PMID:22634058 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing ISO CYP3A5 protein affects the metabolism of Malathion CTD PMID:17110060 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Ddx11 DEAD/H-box helicase 11 increases expression ISO Malathion results in increased expression of DDX11 mRNA CTD PMID:32069766 NCBI chr 9:114,113,642...114,133,908
Ensembl chr 9:114,111,580...114,132,492
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO Malathion results in decreased expression of DUSP1 mRNA CTD PMID:32069766 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 increases expression ISO Malathion results in increased expression of DVL1 mRNA CTD PMID:18204794 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Ehbp1 EH domain binding protein 1 increases response to substance ISO EHBP1 gene SNP results in increased susceptibility to Malathion CTD PMID:23593118 NCBI chr14:106,871,426...107,160,224
Ensembl chr14:106,871,430...107,160,334
JBrowse link
G Epha4 Eph receptor A4 increases expression ISO Malathion results in increased expression of EPHA4 mRNA CTD PMID:32069766 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Malathion results in decreased expression of EPHX1 mRNA CTD PMID:17311802 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Eps8l1 EPS8-like 1 increases expression ISO Malathion results in increased expression of EPS8L1 mRNA CTD PMID:32069766 NCBI chr 1:72,926,106...72,942,433
Ensembl chr 1:72,927,151...72,941,869
JBrowse link
G Esr1 estrogen receptor 1 decreases activity ISO Malathion results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv6 ETS variant transcription factor 6 increases expression ISO Malathion results in increased expression of ETV6 mRNA mutant form CTD PMID:28624474 NCBI chr 4:167,754,684...167,992,370
Ensembl chr 4:167,754,525...167,992,168
JBrowse link
G Fgf6 fibroblast growth factor 6 increases expression ISO Malathion results in increased expression of FGF6 mRNA CTD PMID:32069766 NCBI chr 4:159,563,798...159,572,333
Ensembl chr 4:159,563,798...159,572,333
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Malathion results in increased expression of FGFR1 mRNA CTD PMID:32069766 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Foxo4 forkhead box O4 increases expression ISO Malathion results in increased expression of FOXO4 mRNA CTD PMID:32069766 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression ISO Malathion results in increased expression of FSHR mRNA CTD PMID:32069766 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases activity
EXP [Malathion co-treated with Carbaryl] results in increased activity of G6PD protein; Plant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]
Malathion results in increased activity of G6PD protein
CTD PMID:27214522 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gk glycerol kinase multiple interactions
increases activity
EXP Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein] CTD PMID:25449180 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gk2 glycerol kinase 2 decreases expression EXP Malathion results in decreased expression of GK2 mRNA CTD PMID:25449180 NCBI chr14:13,751,284...13,753,136
Ensembl chr14:13,751,231...13,753,160
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression ISO Malathion results in decreased expression of GNAI2 mRNA CTD PMID:32069766 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gps2 G protein pathway suppressor 2 decreases expression ISO Malathion results in decreased expression of GPS2 mRNA CTD PMID:32069766 NCBI chr10:56,524,327...56,527,447
Ensembl chr10:56,524,468...56,526,987
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP Malathion results in increased activity of GPT protein CTD PMID:25180440 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gramd4 GRAM domain containing 4 decreases expression ISO Malathion results in decreased expression of GRAMD4 mRNA CTD PMID:32069766 NCBI chr 7:126,939,819...127,013,455
Ensembl chr 7:126,939,925...127,013,486
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression EXP Malathion results in increased expression of GSK3B mRNA CTD PMID:25449180 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[Hexachlorocyclohexane co-treated with Malathion] results in decreased activity of GSR protein
zinc chloride inhibits the reaction [Malathion results in decreased activity of GSR protein]
CTD PMID:16718366, PMID:19429256 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO Malathion results in decreased expression of GSTP1 mRNA CTD PMID:32069766 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases expression
ISO [Malathion co-treated with Estrogens] results in increased expression of HRAS mRNA
Malathion results in increased expression of HRAS mRNA; Malathion results in increased expression of HRAS protein
CTD PMID:18204794, PMID:19787260 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions
decreases expression
ISO lavender oil inhibits the reaction [Malathion results in decreased expression of HSD17B3 mRNA] CTD PMID:30409133 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 increases expression ISO Malathion results in increased expression of HSPB2 protein CTD PMID:19607909 NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 decreases expression ISO Malathion results in decreased expression of HTATIP2 mRNA CTD PMID:32069766 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Malathion inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma decreases expression
increases expression
multiple interactions
EXP Malathion results in decreased expression of IFNG protein
Malathion results in increased expression of IFNG mRNA
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]
CTD PMID:19145326, PMID:24810974, PMID:25180440, PMID:28987951 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Malathion results in increased expression of IL13RA2 mRNA CTD PMID:32069766 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Taurine inhibits the reaction [Malathion results in increased expression of IL1B mRNA] CTD PMID:24810974, PMID:25180440, PMID:28987951 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression EXP Malathion results in decreased expression of IL1R2 mRNA CTD PMID:19784758 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA] CTD PMID:24810974, PMID:25180440 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression ISO Malathion results in increased expression of IRAK1 mRNA CTD PMID:32069766 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Kmt2a lysine methyltransferase 2A increases mutagenesis
increases expression
ISO Malathion results in increased mutagenesis of KMT2A gene
Malathion results in increased expression of KMT2A mRNA mutant form
CTD PMID:28624474 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Lat linker for activation of T cells increases expression EXP Malathion results in increased expression of LAT mRNA CTD PMID:19784758 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G Lgals1 galectin 1 decreases expression ISO Malathion results in decreased expression of LGALS1 mRNA CTD PMID:32069766 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like decreases expression ISO Malathion results in decreased expression of HLA-A mRNA CTD PMID:32069766 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 increases expression ISO Malathion results in increased expression of LPCAT4 mRNA CTD PMID:32069766 NCBI chr 3:103,725,762...103,733,888
Ensembl chr 3:103,726,238...103,733,354
JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 decreases expression ISO Malathion results in decreased expression of LZTS2 mRNA CTD PMID:32069766 NCBI chr 1:264,765,256...264,776,553
Ensembl chr 1:264,768,105...264,776,616
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases expression ISO Malathion results in decreased expression of MAP2K3 mRNA CTD PMID:32069766 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions
increases expression
ISO [Malathion co-treated with Estrogens] results in increased expression of MCM2 mRNA
Malathion results in increased expression of MCM2 mRNA
CTD PMID:18204794 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Mill1 MHC I like leukocyte 1 increases expression ISO Malathion results in increased expression of MICA mRNA CTD PMID:32069766 NCBI chr 1:79,631,266...79,657,943
Ensembl chr 1:79,631,668...79,657,941
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein] CTD PMID:24810974, PMID:25180440 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO Malathion results in decreased expression of COX1 mRNA CTD PMID:18214912 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III decreases expression ISO Malathion results in decreased expression of COX3 mRNA CTD PMID:18214912 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Nefh neurofilament heavy affects expression
increases expression
EXP Malathion affects the expression of NEFH mRNA
Malathion results in increased expression of NEFH mRNA
CTD PMID:22954530, PMID:28385489 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO Malathion results in increased activity of NFE2L2 protein CTD PMID:30114225, PMID:30203046 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Malathion promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; Malathion promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ninj1 ninjurin 1 decreases expression ISO Malathion results in decreased expression of NINJ1 mRNA CTD PMID:32069766 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Malathion results in increased expression of NOS2 mRNA CTD PMID:20233601 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Malathion results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
increases activity
ISO Malathion results in increased expression of NR1I3 mRNA
Malathion results in increased activity of NR1I3 protein
CTD PMID:22310298, PMID:28927721, PMID:30203046 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Malathion results in increased expression of NTRK2 mRNA CTD PMID:32069766 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ocln occludin multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of OCLN protein
Malathion results in decreased expression of OCLN protein
CTD PMID:20970449 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G P2rx1 purinergic receptor P2X 1 increases expression EXP Malathion results in increased expression of P2RX1 mRNA CTD PMID:19784758 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Malathion results in increased cleavage of PARP1 protein
Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein]
CTD PMID:29027213 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pax1 paired box 1 increases expression ISO Malathion results in increased expression of PAX1 mRNA CTD PMID:32069766 NCBI chr 3:141,577,124...141,589,849
Ensembl chr 3:141,577,504...141,589,849
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA] CTD PMID:25449180 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression
ISO Atropine inhibits the reaction [Malathion results in increased expression of PCNA] CTD PMID:12762645 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Malathion results in decreased expression of PEBP1 mRNA CTD PMID:32069766 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pfn1 profilin 1 decreases expression ISO Malathion results in decreased expression of PFN1 mRNA CTD PMID:32069766 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Phb prohibitin decreases expression ISO Malathion results in decreased expression of PHB mRNA CTD PMID:32069766 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Malathion results in decreased expression of PLAT mRNA CTD PMID:16079077 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Malathion results in increased expression of PLAU mRNA CTD PMID:32069766 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Malathion results in decreased expression of PML mRNA CTD PMID:32069766 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Malathion results in decreased expression of PPARA mRNA CTD PMID:25689681 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Prkd1 protein kinase D1 increases expression ISO Malathion results in increased expression of PRKD1 mRNA CTD PMID:32069766 NCBI chr 6:71,035,017...71,349,531
Ensembl chr 6:71,035,332...71,349,249
JBrowse link
G Pygl glycogen phosphorylase L multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA] CTD PMID:25449180 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 increases expression ISO Malathion results in increased expression of RAB11FIP3 mRNA CTD PMID:32069766 NCBI chr10:15,348,356...15,433,384
Ensembl chr10:15,349,888...15,381,691
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP Malathion results in increased expression of RELA mRNA
Taurine inhibits the reaction [Malathion results in increased expression of RELA mRNA]
CTD PMID:28987951 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rfc3 replication factor C subunit 3 decreases expression ISO Malathion results in decreased expression of RFC3 mRNA CTD PMID:16079077 NCBI chr12:1,460,581...1,471,344
Ensembl chr12:1,460,538...1,471,357
JBrowse link
G Rnase6 ribonuclease A family member k6 increases expression EXP Malathion results in increased expression of RNASE6 mRNA CTD PMID:19784758 NCBI chr15:28,080,307...28,084,269
Ensembl chr15:28,081,004...28,081,465
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 decreases expression ISO Malathion results in decreased expression of HLA-E mRNA CTD PMID:32069766 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression ISO Malathion results in increased expression of RUNX1 mRNA mutant form CTD PMID:28624474 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Shc1 SHC adaptor protein 1 increases expression ISO Malathion results in increased expression of SHC1 mRNA CTD PMID:32069766 NCBI chr 2:188,745,503...188,757,066
Ensembl chr 2:188,745,503...188,757,066
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Malathion inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Malathion inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO Malathion results in decreased expression of SOCS3 mRNA CTD PMID:32069766 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 increases activity
decreases expression
multiple interactions
EXP
ISO
Malathion results in increased activity of SOD1 protein
Malathion results in decreased expression of SOD1 protein
lavender oil inhibits the reaction [Malathion results in decreased expression of SOD1 protein]
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD1 protein]
CTD PMID:20194575, PMID:30409133 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
EXP
ISO
alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; Malathion results in increased expression of and results in increased activity of SOD2 protein
lavender oil inhibits the reaction [Malathion results in decreased expression of SOD2 protein]
CTD PMID:20194575, PMID:30409133 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression EXP Malathion results in decreased expression of SRSF5 mRNA CTD PMID:19784758 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 increases expression EXP Malathion results in increased expression of ST8SIA1 mRNA CTD PMID:19784758 NCBI chr 4:177,065,266...177,195,942
Ensembl chr 4:177,065,168...177,196,180
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
ISO Malathion results in decreased expression of STAR mRNA
lavender oil inhibits the reaction [Malathion results in decreased expression of STAR mRNA]
CTD PMID:30409133 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Malathion results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression ISO Malathion results in increased expression of TEK mRNA CTD PMID:32069766 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tfrc transferrin receptor increases expression ISO Malathion results in increased expression of TFRC mRNA CTD PMID:32069766 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tg thyroglobulin decreases expression EXP Malathion results in decreased expression of TG mRNA; Malathion results in decreased expression of TG protein CTD PMID:29143548 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression EXP Malathion results in decreased expression of TIMP3 mRNA CTD PMID:19784758 NCBI chr 7:23,543,125...23,594,170
Ensembl chr 7:23,544,215...23,594,133
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of TJP1 protein
Malathion results in decreased expression of TJP1 protein
CTD PMID:20970449 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tjp2 tight junction protein 2 multiple interactions
decreases expression
EXP [Malathion co-treated with Lead] results in decreased expression of TJP2 protein
Malathion results in decreased expression of TJP2 protein
CTD PMID:20970449 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Tlr8 toll-like receptor 8 increases expression ISO Malathion results in increased expression of TLR8 mRNA CTD PMID:32069766 NCBI chr  X:28,539,158...28,562,803
Ensembl chr  X:28,539,158...28,562,803
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP Malathion results in increased expression of TNF mRNA
Taurine inhibits the reaction [Malathion results in increased expression of TNF mRNA]
CTD PMID:28987951 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO
EXP
Atropine inhibits the reaction [Malathion results in increased expression of TP53 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]
Malathion results in increased expression of TRP53 protein
Malathion results in increased expression of TP53 mRNA; Malathion results in increased expression of TP53 protein
CTD PMID:12505448, PMID:12762645, PMID:18204794, PMID:19787260, PMID:21628957 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression
multiple interactions
ISO Malathion results in increased expression of TP53I3 mRNA
[Malathion co-treated with Estrogens] results in increased expression of TP53I3 mRNA
CTD PMID:18204794 NCBI chr13:75,101,759...75,145,967
Ensembl chr13:75,105,615...75,143,441
JBrowse link
G Tpr translocated promoter region, nuclear basket protein increases expression ISO Malathion results in increased expression of TPR mRNA CTD PMID:32069766 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Trim35 tripartite motif-containing 35 decreases expression ISO Malathion results in decreased expression of TRIM35 mRNA CTD PMID:32069766 NCBI chr15:42,960,255...42,976,798
Ensembl chr15:42,960,307...42,976,792
JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 increases expression EXP Malathion results in increased expression of TRPC1 mRNA; Malathion results in increased expression of TRPC1 protein CTD PMID:22674931 NCBI chr 8:103,503,982...103,554,905
Ensembl chr 8:103,503,985...103,554,468
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 increases expression EXP Malathion results in increased expression of TRPC4 mRNA; Malathion results in increased expression of TRPC4 protein CTD PMID:22674931 NCBI chr 2:143,433,102...143,605,757
Ensembl chr 2:143,475,323...143,604,972
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Malathion results in decreased expression of TSHR protein CTD PMID:29143548 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator decreases expression ISO Malathion results in decreased expression of TUSC2 mRNA CTD PMID:32069766 NCBI chr 8:116,318,963...116,322,181
Ensembl chr 8:116,318,963...116,322,181
JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO Malathion results in increased expression of TWIST1 mRNA CTD PMID:32069766 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Tyms thymidylate synthetase decreases expression ISO Malathion results in decreased expression of TYMS mRNA CTD PMID:16079077 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor decreases expression ISO Malathion results in decreased expression of VHL mRNA CTD PMID:32069766 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845
JBrowse link
G Vpreb3 V-set pre-B cell surrogate light chain 3 increases expression ISO Malathion results in increased expression of VPREB3 mRNA CTD PMID:32069766 NCBI chr20:13,656,683...13,661,542
Ensembl chr20:13,656,825...13,657,943
JBrowse link
G Wt1 WT1 transcription factor increases expression ISO Malathion results in increased expression of WT1 mRNA CTD PMID:32069766 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        agrochemical 14503
          malathion 152
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      chalcogen 19391
                        oxygen atom 19353
                          oxygen molecular entity 19353
                            hydroxides 19103
                              oxoacid 18235
                                pnictogen oxoacid 10181
                                  phosphorus oxoacid 9072
                                    phosphoric acids 7831
                                      phosphoric acid 7831
                                        phosphoric acid derivative 7511
                                          phosphate 7511
                                            organic phosphate 7510
                                              organic thiophosphate 2874
                                                diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate 152
                                                  (R)-malathion 152
                                                    malathion 152
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.