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ONTOLOGY REPORT - ANNOTATIONS


Term:malathion
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Accession:CHEBI:6651 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.
Synonyms:exact_synonym: rac-diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate
 related_synonym: Karbofos;   Maldison;   O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl);   O,O-dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate;   O,O-dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate;   O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl;   O,O-dimethyldithiophosphate diethylmercaptosuccinate;   [(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester;   carbophos;   diethyl ((dimethoxyphosphinothioyl)thio)butanedioate;   diethyl (dimethoxyphosphinothioylthio)succinate;   diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate;   mercaptothion
 xref: Beilstein:1804525 "ChemIDplus";   CAS:121-75-5 "ChemIDplus";   CAS:121-75-5 "KEGG COMPOUND";   CAS:121-75-5 "NIST Chemistry WebBook";   DrugBank:DB00772;   Drug_Central:1626 "DrugCentral";   KEGG:C07497;   KEGG:D00534
 xref_mesh: MESH:D008294
 xref: PMID:16083681 "Europe PMC";   PMID:19399610 "Europe PMC";   PMID:28950791 "Europe PMC";   PMID:29235025 "Europe PMC";   PMID:29792547 "Europe PMC";   PMID:29852369 "Europe PMC";   Reaxys:1804525 "Reaxys";   Wikipedia:Malathion


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malathion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Acsm1 acyl-CoA synthetase medium-chain family member 1 JBrowse link 1 189,359,374 189,395,277 RGD:6480464
G Add3 adducin 3 JBrowse link 1 273,854,195 273,961,982 RGD:6480464
G Aff1 AF4/FMR2 family, member 1 JBrowse link 14 7,222,883 7,384,916 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Brd7 bromodomain containing 7 JBrowse link 19 19,672,780 19,701,484 RGD:6480464
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:6480464
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Cdc20 cell division cycle 20 JBrowse link 5 137,260,728 137,264,931 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Cenpf centromere protein F JBrowse link 13 108,132,499 108,178,609 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Cldn5 claudin 5 JBrowse link 11 86,356,292 86,357,718 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 JBrowse link 19 52,647,038 52,705,118 RGD:6480464
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Dvl1 dishevelled segment polarity protein 1 JBrowse link 5 173,295,948 173,308,014 RGD:6480464
G Ehbp1 EH domain binding protein 1 JBrowse link 14 106,871,426 107,160,224 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Etv6 ETS variant transcription factor 6 JBrowse link 4 167,754,684 167,992,370 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gk glycerol kinase JBrowse link X 54,227,291 54,303,897 RGD:6480464
G Gk2 glycerol kinase 2 JBrowse link 14 13,751,284 13,753,136 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:6480464
G Hspb2 heat shock protein family B (small) member 2 JBrowse link 8 55,176,648 55,178,227 RGD:6480464
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Kmt2a lysine methyltransferase 2A JBrowse link 8 49,110,407 49,185,872 RGD:6480464
G Lat linker for activation of T cells JBrowse link 1 197,765,644 197,770,669 RGD:6480464
G Mcm2 minichromosome maintenance complex component 2 JBrowse link 4 120,825,699 120,840,221 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Mt-co1 mitochondrially encoded cytochrome c oxidase I JBrowse link MT 5,323 6,867 RGD:6480464
G Mt-co3 mitochondrially encoded cytochrome c oxidase III JBrowse link MT 8,599 9,382 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Ocln occludin JBrowse link 2 30,527,327 30,577,218 RGD:6480464
G P2rx1 purinergic receptor P2X 1 JBrowse link 10 59,566,268 59,581,328 RGD:6480464
G Pck1 phosphoenolpyruvate carboxykinase 1 JBrowse link 3 171,213,936 171,219,885 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Pygl glycogen phosphorylase L JBrowse link 6 92,597,759 92,643,734 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rfc3 replication factor C subunit 3 JBrowse link 12 1,460,581 1,471,344 RGD:6480464
G Rnase6 ribonuclease A family member k6 JBrowse link 15 28,080,307 28,084,269 RGD:6480464
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:6480464
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 JBrowse link 4 177,065,266 177,195,942 RGD:6480464
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:6480464
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:6480464
G Tjp1 tight junction protein 1 JBrowse link 1 126,146,489 126,515,359 RGD:6480464
G Tjp2 tight junction protein 2 JBrowse link 1 241,945,816 242,084,044 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tp53i3 tumor protein p53 inducible protein 3 JBrowse link 13 75,101,759 75,145,967 RGD:6480464
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 JBrowse link 8 103,503,982 103,554,905 RGD:6480464
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 JBrowse link 2 143,433,102 143,605,757 RGD:6480464
G Tyms thymidylate synthetase JBrowse link 9 121,918,875 121,931,564 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        agrochemical 13321
          malathion 92
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      chalcogen 19233
                        oxygen atom 19188
                          oxygen molecular entity 19188
                            hydroxides 18965
                              oxoacid 18076
                                pnictogen oxoacid 8534
                                  phosphorus oxoacid 8429
                                    phosphoric acids 7314
                                      phosphoric acid 7314
                                        phosphoric acid derivative 6965
                                          phosphate 6965
                                            organic phosphate 6964
                                              organic thiophosphate 2772
                                                diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate 92
                                                  (R)-malathion 92
                                                    malathion 92
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.