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Term:4-methylaeruginoic acid
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Accession:CHEBI:66368 term browser browse the term
Definition:A 1,3-thiazole that is 4,5-dihydro-1,3-thiazole-4-carboxylic acid substituted by a 2-hydroxyphenyl group at position 2 and a methyl group at position 4 (the 4S stereoisomer). It is isolated from the culture broth of Streptomyces sp.KCTC9303 and exhibits potent cytotoxic activites against number of tumour cell lines.
Synonyms:exact_synonym: (4S)-2-(2-hydroxyphenyl)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
 related_synonym: Formula=C11H11NO3S;   InChI=1S/C11H11NO3S/c1-11(10(14)15)6-16-9(12-11)7-4-2-3-5-8(7)13/h2-5,13H,6H2,1H3,(H,14,15)/t11-/m1/s1;   InChIKey=OXCVIPGXPILNPT-LLVKDONJSA-N;   SMILES=C[C@@]1(CSC(=N1)c1ccccc1O)C(O)=O
 xref: Chemspider:10446249;   PMID:10395484 "Europe PMC";   PMID:9439697 "Europe PMC";   Reaxys:10437963 "Reaxys"

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            4-methylaeruginoic acid 0
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  CHEBI ontology 0
    subatomic particle 0
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                      carbon group element atom 0
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                          organic molecular entity 0
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                                    monocyclic heteroarene 0
                                      azole 0
                                        thiazoles 0
                                          1,3-thiazoles 0
                                            4-methylaeruginoic acid 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.