Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:4-methylaeruginoic acid
go back to main search page
Accession:CHEBI:66368 term browser browse the term
Definition:A 1,3-thiazole that is 4,5-dihydro-1,3-thiazole-4-carboxylic acid substituted by a 2-hydroxyphenyl group at position 2 and a methyl group at position 4 (the 4S stereoisomer). It is isolated from the culture broth of Streptomyces sp.KCTC9303 and exhibits potent cytotoxic activites against number of tumour cell lines.
Synonyms:exact_synonym: (4S)-2-(2-hydroxyphenyl)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
 related_synonym: Formula=C11H11NO3S;   InChI=1S/C11H11NO3S/c1-11(10(14)15)6-16-9(12-11)7-4-2-3-5-8(7)13/h2-5,13H,6H2,1H3,(H,14,15)/t11-/m1/s1;   InChIKey=OXCVIPGXPILNPT-LLVKDONJSA-N;   SMILES=C[C@@]1(CSC(=N1)c1ccccc1O)C(O)=O
 xref: Chemspider:10446249;   PMID:10395484 "Europe PMC";   PMID:9439697 "Europe PMC";   Reaxys:10437963 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20971
    role 20952
      biological role 20950
        biochemical role 19959
          metabolite 19886
            4-methylaeruginoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20971
    subatomic particle 20965
      composite particle 20965
        hadron 20965
          baryon 20965
            nucleon 20965
              atomic nucleus 20965
                atom 20965
                  main group element atom 20803
                    p-block element atom 20803
                      carbon group element atom 20543
                        carbon atom 20519
                          organic molecular entity 20519
                            organic molecule 20371
                              organic cyclic compound 20047
                                organic heterocyclic compound 18970
                                  heteroarene 15936
                                    monocyclic heteroarene 13226
                                      azole 12448
                                        thiazoles 403
                                          1,3-thiazoles 351
                                            4-methylaeruginoic acid 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.