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Term:4-methylaeruginoic acid
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Accession:CHEBI:66368 term browser browse the term
Definition:A 1,3-thiazole that is 4,5-dihydro-1,3-thiazole-4-carboxylic acid substituted by a 2-hydroxyphenyl group at position 2 and a methyl group at position 4 (the 4S stereoisomer). It is isolated from the culture broth of Streptomyces sp.KCTC9303 and exhibits potent cytotoxic activites against number of tumour cell lines.
Synonyms:exact_synonym: (4S)-2-(2-hydroxyphenyl)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
 related_synonym: Formula=C11H11NO3S;   InChI=1S/C11H11NO3S/c1-11(10(14)15)6-16-9(12-11)7-4-2-3-5-8(7)13/h2-5,13H,6H2,1H3,(H,14,15)/t11-/m1/s1;   InChIKey=OXCVIPGXPILNPT-LLVKDONJSA-N;   SMILES=C[C@@]1(CSC(=N1)c1ccccc1O)C(O)=O
 xref: Chemspider:10446249;   PMID:10395484 "Europe PMC";   PMID:9439697 "Europe PMC";   Reaxys:10437963 "Reaxys"

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  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            4-methylaeruginoic acid 0
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  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  heteroarene 15295
                                    monocyclic heteroarene 11645
                                      azole 10501
                                        thiazoles 397
                                          1,3-thiazoles 340
                                            4-methylaeruginoic acid 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.