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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:magnesium dichloride
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Accession:CHEBI:6636 term browser browse the term
Definition:A magnesium salt comprising of two chlorine atoms bound to a magnesium atom.
Synonyms:related_synonym: Formula=Cl2Mg;   InChI=1S/2ClH.Mg/h2*1H;/q;;+2/p-2;   InChIKey=TWRXJAOTZQYOKJ-UHFFFAOYSA-L;   Magnesium chloride;   Magnesium chloride anhydrous;   Magnesiumchlorid;   MgCl2;   SMILES=[Mg++].[Cl-].[Cl-]
 xref: CAS:7786-30-3;   Gmelin:9305;   KEGG:C07755
 xref_mesh: MESH:D015636
 xref: MolBase:1868;   Reaxys:8128169


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magnesium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions EXP Magnesium Chloride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions
decreases activity		 EXP Magnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of 9-cis-retinal]; Magnesium Chloride inhibits the reaction [ALDH1A1 protein affects the oxidation of Retinaldehyde]
Magnesium Chloride results in decreased activity of ALDH1A1 protein		 CTD PMID:10998257 PMID:17167544 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO
EXP		 Magnesium Chloride results in increased expression of BAX protein CTD PMID:17977900 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 increases activity ISO
EXP		 Magnesium Chloride results in increased activity of CASP3 protein CTD PMID:17977900 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Magnesium Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride CTD PMID:21107535 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO Magnesium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO Magnesium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:68,375,518...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Kif5a kinesin family member 5A multiple interactions ISO Magnesium Chloride affects the reaction [zinc chloride results in decreased activity of KIF5A protein] CTD PMID:28122263 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858 		JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Magnesium Chloride results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:94,251,803...94,258,646
Ensembl chr 1:94,251,803...94,258,646 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [2-tert-butylhydroquinone promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]] which results in decreased susceptibility to Magnesium Chloride CTD PMID:21107535 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nudt9 nudix hydrolase 9 multiple interactions
increases activity		 ISO Dithiothreitol inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Magnesium Chloride results in increased activity of NUDT9 protein]]; Fluorides inhibits the reaction [Magnesium Chloride results in increased activity of NUDT9 protein]; Hydrogen Peroxide inhibits the reaction [Magnesium Chloride results in increased activity of NUDT9 protein] CTD PMID:16860484 NCBI chr14:5,675,376...5,693,332
Ensembl chr14:5,675,382...5,693,142 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO Magnesium Chloride affects the reaction [Nickel binds to SERPINE1 protein] CTD PMID:21280128 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 multiple interactions ISO [Magnesium Chloride co-treated with Phosphatidylserines] promotes the reaction [SMPD3 protein results in increased degradation of Sphingomyelins] CTD PMID:12566438 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO Magnesium Chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; Magnesium Chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tp53 tumor protein p53 affects expression EXP Magnesium Chloride affects the expression of TP53 mRNA CTD PMID:10506531 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20060
    chemical entity 20059
      chemical substance 13315
        mineral 4153
          mineral nutrient 420
            inorganic magnesium salt 18
              magnesium dichloride 18
                magnesium dichloride dihydrate 0
                magnesium dichloride hexahydrate 0
                magnesium dichloride monohydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20060
    subatomic particle 20059
      composite particle 20059
        hadron 20059
          baryon 20059
            nucleon 20059
              atomic nucleus 20059
                atom 20059
                  main group element atom 19962
                    p-block element atom 19962
                      halogen 18515
                        chlorine atom 18310
                          chlorine molecular entity 18310
                            elemental chlorine 8538
                              monoatomic chlorine 8521
                                chloride 8521
                                  chloride salt 8521
                                    inorganic chloride 8281
                                      magnesium dichloride 18
                                        magnesium dichloride dihydrate 0
                                        magnesium dichloride hexahydrate 0
                                        magnesium dichloride monohydrate 0
paths to the root