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ONTOLOGY REPORT - ANNOTATIONS


Term:UK-2B
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Accession:CHEBI:66340 term browser browse the term
Definition:A lactone which is 9-methyl-1,5-dioxonane-2,6-dione substituted by a benzyl group at position 8, a [(3-hydroxy-4-methoxypyridine-2-yl)carbonyl]amino group at position 3 and a (2-methylbut-2-enoyl)oxy group at position 7. It is isolated from the mycelia cake of Streptomyces sp. 517-02 and exhibits potent antifungal activity.
Synonyms:related_synonym: 8-benzyl-3-[(3-hydroxy-4-methoxypyridine-2-carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl (2E)-2-methylbut-2-enoate;   Formula=C27H30N2O9;   InChI=1S/C27H30N2O9/c1-5-15(2)25(32)38-23-16(3)37-27(34)19(29-24(31)21-22(30)20(35-4)11-12-28-21)14-36-26(33)18(23)13-17-9-7-6-8-10-17/h5-12,16,18-19,23,30H,13-14H2,1-4H3,(H,29,31)/b15-5+;   InChIKey=NRCFYQYMBDTOBT-PJQLUOCWSA-N;   SMILES=COc1ccnc(C(=O)NC2COC(=O)C(Cc3ccccc3)C(OC(=O)C(\\C)=C\\C)C(C)OC2=O)c1O
 xref: PMID:10048572 "Europe PMC";   PMID:10580388 "Europe PMC";   PMID:11560380 "Europe PMC";   PMID:12760689 "Europe PMC";   PMID:8784423 "Europe PMC";   PMID:9031668 "Europe PMC";   Reaxys:7611502 "Reaxys"


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  CHEBI ontology 20742
    role 20720
      biological role 20719
        antimicrobial agent 17942
          UK-2B 0
Path 2
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  CHEBI ontology 20742
    subatomic particle 20735
      composite particle 20735
        hadron 20735
          baryon 20735
            nucleon 20735
              atomic nucleus 20735
                atom 20735
                  main group element atom 20655
                    p-block element atom 20655
                      carbon group element atom 20391
                        carbon atom 20367
                          organic molecular entity 20367
                            organic group 19036
                              organic divalent group 19026
                                organodiyl group 19026
                                  carbonyl group 18997
                                    carbonyl compound 18997
                                      carboxylic acid 18668
                                        carboacyl group 17277
                                          univalent carboacyl group 17277
                                            carbamoyl group 16928
                                              carboxamide 16928
                                                monocarboxylic acid amide 13426
                                                  UK-2B 0
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