The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A cyclodepsipeptide isolated from Jaspis splendens and has been shown to exhibit antineoplastic activity. It is an actin polymerization and stabilization inducer.
jasplakinolide inhibits the reaction [UPF1 protein binds to ACTG1 protein]; jasplakinolide inhibits the reaction [UPF2 protein binds to ACTG1 protein]; jasplakinolide inhibits the reaction [UPF3B protein binds to ACTG1 protein]
jasplakinolide inhibits the reaction [AHNAK protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [AHNAK protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [AHNAK protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [AHNAK protein affects the localization of SNAI1 protein]
jasplakinolide results in increased expression of and results in increased secretion of CCN1 protein; YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN1 protein] jasplakinolide results in increased expression of CCN1 mRNA
jasplakinolide results in increased expression of CCN2 mRNA jasplakinolide results in increased expression of and results in increased secretion of CCN2 protein; YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN2 protein]
jasplakinolide results in decreased expression of CDH1 protein jasplakinolide inhibits the reaction [AHNAK protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the expression of CDH1 protein]
jasplakinolide inhibits the reaction [AHNAK protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the expression of CDH2 protein]
jasplakinolide inhibits the reaction [EIF4E protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the localization of SNAI1 protein]
jasplakinolide results in increased expression of GDF15 mRNA; jasplakinolide results in increased expression of GDF15 protein [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein]
jasplakinolide promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]
jasplakinolide promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA] jasplakinolide inhibits the reaction [latrunculin B promotes the reaction [IL1B protein results in increased expression of NOS2 protein]]
jasplakinolide promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA] jasplakinolide inhibits the reaction [latrunculin B promotes the reaction [IL1B protein results in increased expression of NOS2 protein]]
jasplakinolide inhibits the reaction [Cholesterol deficiency results in decreased activity of P2RX1 protein] jasplakinolide affects the localization of P2RX1 protein
jasplakinolide inhibits the reaction [S100A1 protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the localization of SNAI1 protein]
jasplakinolide inhibits the reaction [SEPTIN9 protein affects the expression of CDH1 protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the expression of CDH2 protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the localization of SNAI1 protein]
jasplakinolide inhibits the reaction [AHNAK protein affects the localization of SNAI1 protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the localization of SNAI1 protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the localization of SNAI1 protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the localization of SNAI1 protein]
jasplakinolide inhibits the reaction [TNF protein affects the localization of ICAM1 protein]; jasplakinolide inhibits the reaction [TNF protein affects the localization of VCAM1 protein]; jasplakinolide promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA]
jasplakinolide inhibits the reaction [AHNAK protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [EIF4E protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [S100A1 protein affects the expression of VIM protein]; jasplakinolide inhibits the reaction [SEPTIN9 protein affects the expression of VIM protein]
jasplakinolide results in decreased phosphorylation of and affects the localization of YAP1 protein; YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN1 protein]; YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN2 protein]