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ONTOLOGY REPORT - ANNOTATIONS


Term:hookerianamide J
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Accession:CHEBI:66022 term browser browse the term
Definition:A steroid alkaloid that is 5alpha-preg-16-ene substituted by a hydroxy group at position 4, a N,N-dimethylamino group at position 20 and a N-senecoylamino group at position 3 (the 3beta,4beta,20S stereoisomer). Isolated from Sarcococca hookeriana, it exhibits antileishmanial and antibacterial activities.
Synonyms:exact_synonym: N-[(3beta,4beta,5alpha,20S)-20-(dimethylamino)-4-hydroxypregn-16-en-3-yl]-3-methylbut-2-enamide
 related_synonym: (20S)-20-(N,N-dimethylamino)-3beta-(N-senecoylamino)-5alpha-preg-16-en-4beta-ol;   Formula=C28H46N2O2;   InChI=1S/C28H46N2O2/c1-17(2)16-25(31)29-24-13-15-28(5)22-12-14-27(4)20(18(3)30(6)7)10-11-21(27)19(22)8-9-23(28)26(24)32/h10,16,18-19,21-24,26,32H,8-9,11-15H2,1-7H3,(H,29,31)/t18-,19-,21-,22-,23-,24-,26+,27+,28+/m0/s1;   InChIKey=UBWMSSICUOCSHT-BJHCZKLTSA-N;   SMILES=[H][C@@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)C(=CC[C@@]34[H])[C@H](C)N(C)C)[C@@]1(C)CC[C@H](NC(=O)C=C(C)C)[C@@H]2O
 xref: PMID:18681480 "Europe PMC";   Reaxys:18885924 "Reaxys"


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Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        antimicrobial agent 17227
          antibacterial agent 12937
            hookerianamide J 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        monocarboxylic acid 17268
                                          fatty acid 15817
                                            unsaturated fatty acid 894
                                              monounsaturated fatty acid 399
                                                butenoic acid 19
                                                  2-butenoic acid 19
                                                    3-methylbut-2-enoic acid 0
                                                      hookerianamide J 0
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