Term: | eupaheliangolide A |
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Accession: | CHEBI:65879
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Definition: | A sesquiterpene lactone of the heliangolide group isolated from Eupatorium kiirunense and exhibits cytotoxicity against human oral epidermoid (KB), cervical epitheloid (Hela) and liver (hepa59T/VGH) carcinoma cells. |
Synonyms: | exact_synonym: | (3aR,4R,6R,7E,10Z,11aR)-6-hydroxy-6,10-dimethyl-3-methylidene-2,9-dioxo-2,3,3a,4,5,6,9,11a-octahydrocyclodeca[b]furan-4-yl(2E)-2-methylbut-2-enoate |
| related_synonym: | 8beta-tigloyloxy-10alpha-hydroxy-3-oxo-6betaH,7alphaH-helianga-1E,4Z,11(13)-trien-6,12-olide; Formula=C20H24O6; InChI=1S/C20H24O6/c1-6-11(2)18(22)26-16-10-20(5,24)8-7-14(21)12(3)9-15-17(16)13(4)19(23)25-15/h6-9,15-17,24H,4,10H2,1-3,5H3/b8-7+,11-6+,12-9-/t15-,16-,17+,20+/m1/s1; InChIKey=AXSMKFJOTFGINI-AWYRNCDDSA-N; SMILES=[H][C@]12OC(=O)C(=C)[C@]1([H])[C@@H](C[C@@](C)(O)\\C=C\\C(=O)\\C(C)=C/2)OC(=O)C(\\C)=C\\C |
| xref: | PMID:15921421; Reaxys:11258334 |
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