Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ergosterol peroxide
go back to main search page
Accession:CHEBI:65858 term browser browse the term
Definition:An ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities.
Synonyms:exact_synonym: (3S,5S,8S,9R,10R,13R,14R,17R)-17-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-1,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-2H-5,8-epidioxycyclopenta[a]phenanthren-3-ol
 related_synonym: (22E,24R)-5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol;   (24R)-5alpha,8alpha-epidioxy-24-methylcholesta-6,22-dien-3beta-ol;   (3beta,5alpha,8alpha,22E)-5,8-epidioxyergosta-6,22-dien-3-ol;   5alpha,8alpha-epidioxy-22E-ergosta-6,22-dien-3beta-ol;   Formula=C28H44O3;   InChI=1S/C28H44O3/c1-18(2)19(3)7-8-20(4)22-9-10-23-25(22,5)13-12-24-26(6)14-11-21(29)17-27(26)15-16-28(23,24)31-30-27/h7-8,15-16,18-24,29H,9-14,17H2,1-6H3/b8-7+/t19-,20+,21-,22+,23+,24+,25+,26+,27+,28-/m0/s1;   InChIKey=VXOZCESVZIRHCJ-KGHQQZOUSA-N;   SMILES=[H][C@@]1(CC[C@]2([H])[C@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)C[C@@]33OO[C@@]21C=C3)[C@H](C)\\C=C\\[C@H](C)C(C)C;   ergosterol 5alpha,8alpha-epidioxide;   ergosterol endoperoxide;   ergosterol-5,8-peroxide;   peroxyergosterol
 xref: CAS:2061-64-5;   Chemspider:4508532
 xref_mesh: MESH:C036071
 xref: PMID:10423860;   PMID:11014261;   PMID:15665489;   PMID:21341709;   PMID:21428374;   PMID:21469696;   PMID:22083593;   PMID:9635497;   Reaxys:96852;   Wikipedia:Ergosterol_peroxide



show annotations for term's descendants           Sort by:
 
ergosterol peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO ergosterol-5,8-peroxide results in increased activity of CASP3 protein CTD PMID:20100469 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        biochemical role 19640
          metabolite 19623
            ergosterol peroxide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic molecule 19822
                              organic cyclic compound 19575
                                organic polycyclic compound 17176
                                  steroid 14380
                                    hydroxy steroid 14096
                                      3-hydroxy steroid 12143
                                        sterol 441
                                          phytosterols 68
                                            ergosterol 13
                                              ergosterol peroxide 1
paths to the root