CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: carnosic acid
Accession: CHEBI:65585
browse the term
Definition: An abietane diterpenoid that is abieta-8,11,13-triene substituted by hydroxy groups at positions 11 and 12 and a carboxy group at position 20. It is isolated from rosemary (Rosmarinus officinalis) and common sage (Salvia officinalis) and exhibits anti-angiogenic, antineoplastic, antioxidant and anti-HIV activity.
Synonyms: exact_synonym: 11,12-dihydroxyabieta-8,11,13-trien-20-oic acid
related_synonym: (4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-(propan-2-yl)-1,3,4,9,10,10a-hexahydrophenanthrene-4a(2H)-carboxylic acid; 11,12-dihydroxy-13-isopropylpodocarpa-8,11,13-trien-17-oic acid; Formula=C20H28O4; InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1; InChIKey=QRYRORQUOLYVBU-VBKZILBWSA-N; SMILES=C1CC([C@]2([C@](C1)(C3=C(CC2)C=C(C(=C3O)O)C(C)C)C(=O)O)[H])(C)C; Salvin
xref: CAS:3650-09-7
xref_mesh: MESH:C018381
xref: MetaCyc:CPD-18103; PMID:11504768; PMID:17177234; PMID:22232247; PMID:22246562; PMID:22687582; PMID:22828666; PMID:26976595; PMID:27694001; PMID:27703160; PMID:27716981; PMID:27957651; PMID:28008719; PMID:28159594; PMID:28282784; PMID:28288941; PMID:28343998; PMID:28440400; PMID:28674855; PMID:28877257; PMID:28887507; PMID:28916593; PMID:28918123; PMID:29100552; PMID:8229021; Reaxys:2707918; Wikipedia:Carnosic_acid
cyclic_relationship: is_conjugate_acid_of CHEBI:138943
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A2m
alpha-2-macroglobulin
decreases expression
ISO
salvin results in decreased expression of A2M protein
CTD
PMID:35926579
NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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Aacs
acetoacetyl-CoA synthetase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of AACS mRNA]
CTD
PMID:35202923
NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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Abat
4-aminobutyrate aminotransferase
increases expression
ISO
salvin results in increased expression of ABAT protein
CTD
PMID:35926579
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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Abca6
ATP binding cassette subfamily A member 6
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ABCA6 mRNA]
CTD
PMID:35202923
NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
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Abhd11
abhydrolase domain containing 11
increases expression
ISO
salvin results in increased expression of ABHD11 protein
CTD
PMID:35926579
NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398
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Abi1
abl-interactor 1
increases expression
ISO
salvin results in increased expression of ABI1 protein
CTD
PMID:35926579
NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792
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Acly
ATP citrate lyase
increases expression
ISO
salvin results in increased expression of ACLY protein
CTD
PMID:35926579
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Acss2
acyl-CoA synthetase short-chain family member 2
increases expression
ISO
salvin results in increased expression of ACSS2 protein
CTD
PMID:35926579
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Actn1
actinin, alpha 1
increases expression
ISO
salvin results in increased expression of ACTN1 protein
CTD
PMID:35926579
NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
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Adcy9
adenylate cyclase 9
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ADCY9 mRNA]
CTD
PMID:35202923
NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
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Adgre1
adhesion G protein-coupled receptor E1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ADGRE1 mRNA]
CTD
PMID:35202923
NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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Adgre4
adhesion G protein-coupled receptor E4
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of ADGRE4 mRNA]
CTD
PMID:35202923
NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760
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Adh1c
alcohol dehydrogenase 1C (class I), gamma polypeptide
increases expression
ISO
salvin results in increased expression of ADH1 protein
CTD
PMID:35926579
NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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Aebp1
AE binding protein 1
decreases expression
ISO
salvin results in decreased expression of AEBP1 protein
CTD
PMID:35926579
NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
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Agps
alkylglycerone phosphate synthase
decreases expression
ISO
salvin results in decreased expression of AGPS protein
CTD
PMID:35926579
NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
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Ahsg
alpha-2-HS-glycoprotein
decreases expression
ISO
salvin results in decreased expression of AHSG protein
CTD
PMID:35926579
NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
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Akt1
AKT serine/threonine kinase 1
increases phosphorylation decreases phosphorylation
ISO
salvin results in increased phosphorylation of AKT1 protein salvin results in decreased phosphorylation of AKT1 protein
CTD
PMID:25178877 PMID:25271104
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alb
albumin
decreases expression
ISO
salvin results in decreased expression of ALB protein
CTD
PMID:35926579
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
decreases expression
ISO
salvin results in decreased expression of ALDH1A3 protein
CTD
PMID:35926579
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Apaf1
apoptotic peptidase activating factor 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of APAF1 protein]
CTD
PMID:29854073
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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Apoa1
apolipoprotein A1
decreases expression
ISO
salvin results in decreased expression of APOA1 protein
CTD
PMID:35926579
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Apoa4
apolipoprotein A4
decreases expression
ISO
salvin results in decreased expression of APOA4 protein
CTD
PMID:35926579
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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Apoe
apolipoprotein E
decreases expression
ISO
salvin results in decreased expression of APOE protein
CTD
PMID:35926579
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Apoh
apolipoprotein H
decreases expression
ISO
salvin results in decreased expression of APOH protein
CTD
PMID:35926579
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
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Asns
asparagine synthetase (glutamine-hydrolyzing)
decreases expression
ISO
salvin results in decreased expression of ASNS protein
CTD
PMID:35926579
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Aspa
aspartoacylase
decreases expression
ISO
salvin results in decreased expression of ASPA protein
CTD
PMID:35926579
NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272
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Aspn
asporin
increases expression
ISO
salvin results in increased expression of ASPN protein
CTD
PMID:35926579
NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
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Atp12a
ATPase H+/K+ transporting non-gastric alpha2 subunit
increases expression
ISO
salvin results in increased expression of ATP12A protein
CTD
PMID:35926579
NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229
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B2m
beta-2 microglobulin
increases expression
ISO
salvin results in increased expression of B2M protein
CTD
PMID:35926579
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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Bad
BCL2-associated agonist of cell death
multiple interactions decreases phosphorylation increases expression
ISO
salvin promotes the reaction [arsenic trioxide results in decreased phosphorylation of BAD protein] salvin results in decreased phosphorylation of BAD protein salvin results in increased expression of BAD protein
CTD
PMID:23239002 PMID:28918123
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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Basp1
brain abundant, membrane attached signal protein 1
decreases expression
ISO
salvin results in decreased expression of BASP1 protein
CTD
PMID:35926579
NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO
salvin inhibits the reaction [Paraquat results in increased expression of BAX protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein] salvin results in increased expression of BAX protein salvin inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
CTD
PMID:26577515 PMID:26686574 PMID:28918123 PMID:29854073
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcas2
BCAS2, pre-mRNA processing factor
decreases expression
ISO
salvin results in decreased expression of BCAS2 protein
CTD
PMID:35926579
NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389
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Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
EXP ISO
salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein] Acetylcysteine inhibits the reaction [salvin results in decreased expression of BCL2 protein]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]]; salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]; salvin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; salvin inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein] salvin inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
CTD
PMID:25446857 PMID:26577515 PMID:26686574 PMID:28918123 PMID:29854073 PMID:30707903 More...
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l2
Bcl2-like 2
multiple interactions
ISO
salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of BCL2L2 protein]
CTD
PMID:24557422
NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
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Bmp5
bone morphogenetic protein 5
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of BMP5 mRNA]
CTD
PMID:35202923
NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
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Bzw2
basic leucine zipper and W2 domains 2
decreases expression
ISO
salvin results in decreased expression of BZW2 protein
CTD
PMID:35926579
NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628
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C3
complement C3
decreases expression
ISO
salvin results in decreased expression of C3 protein
CTD
PMID:35926579
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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C4b
complement C4B
decreases expression
ISO
salvin results in decreased expression of C4B protein
CTD
PMID:35926579
NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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Camp
cathelicidin antimicrobial peptide
decreases expression
ISO
salvin results in decreased expression of CAMP protein
CTD
PMID:35926579
NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
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Car2
carbonic anhydrase 2
increases expression
ISO
salvin results in increased expression of CA2 protein
CTD
PMID:35926579
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Casp14
caspase 14
increases expression
ISO
salvin results in increased expression of CASP14 protein
CTD
PMID:35926579
NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405
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Casp3
caspase 3
multiple interactions increases cleavage
EXP ISO
salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP3 protein]; GSTP1 mutant form inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased cleavage of CASP3 protein]; salvin inhibits the reaction [Acrylamide results in increased expression of CASP3 mRNA]; salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]; salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP3 protein] salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]
CTD
PMID:24557422 PMID:25271104 PMID:25446857 PMID:26577515 PMID:26686574 PMID:28159594 PMID:28918123 PMID:29854073 PMID:30707903 PMID:31705926 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp6
caspase 6
decreases expression
ISO
salvin results in decreased expression of CASP6 protein
CTD
PMID:35926579
NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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Casp8
caspase 8
multiple interactions increases cleavage
ISO
Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP8 protein] salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein]
CTD
PMID:28918123 PMID:29854073
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
increases activity multiple interactions increases cleavage
ISO
salvin results in increased activity of CASP9 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein]]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP9 protein]; salvin inhibits the reaction [Acrylamide results in increased expression of CASP9 mRNA]; salvin inhibits the reaction [Paraquat results in increased activity of CASP9 protein]; salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein]; salvin promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein] salvin inhibits the reaction [sodium arsenite results in increased cleavage of CASP9 protein]
CTD
PMID:23239002 PMID:26577515 PMID:26686574 PMID:28159594 PMID:28918123 PMID:29854073 More...
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions
ISO
salvin inhibits the reaction [Acrylamide results in decreased activity of CAT protein]; salvin inhibits the reaction [Acrylamide results in decreased expression of CAT mRNA] salvin inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD
PMID:28159594 PMID:29854073
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cd14
CD14 molecule
multiple interactions
ISO
[salvin co-treated with Tretinoin] results in increased expression of CD14 protein; salvin promotes the reaction [Calcitriol results in increased expression of CD14 protein]
CTD
PMID:11504768
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd177
CD177 molecule
decreases expression
ISO
salvin results in decreased expression of CD177 protein
CTD
PMID:35926579
NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
increases expression multiple interactions
ISO
salvin results in increased expression of CDKN1B protein salvin promotes the reaction [arsenic trioxide results in increased expression of CDKN1B protein]
CTD
PMID:23239002
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Cela1
chymotrypsin like elastase 1
decreases expression
ISO
salvin results in decreased expression of CELA1 protein
CTD
PMID:35926579
NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285
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Cela3b
chymotrypsin like elastase 3B
decreases expression
ISO
salvin results in decreased expression of CELA3B protein
CTD
PMID:35926579
NCBI chr 5:149,628,773...149,636,937
Ensembl chr 5:149,628,773...149,636,937
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Chp2
calcineurin-like EF hand protein 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CHP2 mRNA]
CTD
PMID:35202923
NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139
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Ckmt1
creatine kinase, mitochondrial 1
increases expression
ISO
salvin results in increased expression of CKMT1 protein
CTD
PMID:35926579
NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758
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Clca1
chloride channel accessory 1
increases expression
ISO
salvin results in increased expression of CLCA1 protein
CTD
PMID:35926579
NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
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Clca4
chloride channel accessory 4
decreases expression
ISO
salvin results in decreased expression of CLCA4A protein
CTD
PMID:35926579
NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089
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Clec14a
C-type lectin domain containing 14A
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CLEC14A mRNA]
CTD
PMID:35202923
NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
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Clic5
chloride intracellular channel 5
increases expression
ISO
salvin results in increased expression of CLIC5 protein
CTD
PMID:35926579
NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427
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Clns1a
chloride nucleotide-sensitive channel 1A
increases expression
ISO
salvin results in increased expression of CLNS1A protein
CTD
PMID:35926579
NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661
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Clu
clusterin
decreases expression
ISO
salvin results in decreased expression of CLU protein
CTD
PMID:35926579
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Col18a1
collagen type XVIII alpha 1 chain
decreases expression
ISO
salvin results in decreased expression of COL18A1 protein
CTD
PMID:35926579
NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
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Col6a3
collagen type VI alpha 3 chain
decreases expression
ISO
salvin results in decreased expression of COL6A3 protein
CTD
PMID:35926579
NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
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Cox6a1
cytochrome c oxidase subunit 6A1
increases expression
ISO
salvin results in increased expression of COX6A1 protein
CTD
PMID:35926579
NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
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Cp
ceruloplasmin
decreases expression
ISO
salvin results in decreased expression of CP protein
CTD
PMID:35926579
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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Cpb1
carboxypeptidase B1
decreases expression
ISO
salvin results in decreased expression of CPB1 protein
CTD
PMID:35926579
NCBI chr 2:102,755,241...102,785,628
Ensembl chr 2:102,755,241...102,785,628
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Cpox
coproporphyrinogen oxidase
increases expression
ISO
salvin results in increased expression of CPOX protein
CTD
PMID:35926579
NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
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Cpsf7
cleavage and polyadenylation specific factor 7
decreases expression
ISO
salvin results in decreased expression of CPSF7 protein
CTD
PMID:35926579
NCBI chr 1:207,167,690...207,191,938
Ensembl chr 1:207,167,859...207,191,905
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Crnkl1
crooked neck pre-mRNA splicing factor 1
decreases expression
ISO
salvin results in decreased expression of CRNKL1 protein
CTD
PMID:35926579
NCBI chr 3:133,338,593...133,354,329
Ensembl chr 3:133,337,039...133,354,302 Ensembl chr 6:133,337,039...133,354,302
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Ctrl
chymotrypsin-like
decreases expression
ISO
salvin results in decreased expression of CTRB1 protein
CTD
PMID:35926579
NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626
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Cybb
cytochrome b-245 beta chain
decreases expression
ISO
salvin results in decreased expression of CYBB protein
CTD
PMID:35926579
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Cyp20a1
cytochrome P450, family 20, subfamily a, polypeptide 1
decreases expression
ISO
salvin results in decreased expression of CYP20A1 protein
CTD
PMID:35926579
NCBI chr 9:61,755,804...61,805,123
Ensembl chr 9:61,755,790...61,805,123
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CYP2B10 mRNA]
CTD
PMID:35202923
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp2c66
cytochrome P450, family 2, subfamily c, polypeptide 66
decreases expression
ISO
salvin results in decreased expression of CYP2C66 protein
CTD
PMID:35926579
NCBI chr 1:237,078,517...237,169,841
Ensembl chr 1:237,078,517...237,169,650
G
Cyp51
cytochrome P450, family 51
decreases expression
ISO
salvin results in decreased expression of CYP51A1 protein
CTD
PMID:35926579
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of CYP7A1 mRNA]
CTD
PMID:35202923
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Dmbt1
deleted in malignant brain tumors 1
decreases expression
ISO
salvin results in decreased expression of DMBT1 protein
CTD
PMID:35926579
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
G
Dnajc10
DnaJ heat shock protein family (Hsp40) member C10
decreases expression
ISO
salvin results in decreased expression of DNAJC10 protein
CTD
PMID:35926579
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
G
Dop1b
DOP1 leucine zipper like protein B
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of DOP1B mRNA]
CTD
PMID:35202923
NCBI chr11:33,024,376...33,125,931
Ensembl chr11:33,024,411...33,125,931
G
Dpep1
dipeptidase 1
decreases expression
ISO
salvin results in decreased expression of DPEP1 protein
CTD
PMID:35926579
NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of EHHADH mRNA]
CTD
PMID:35202923
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
G
Elane
elastase, neutrophil expressed
decreases expression
ISO
salvin results in decreased expression of ELANE protein
CTD
PMID:35926579
NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
G
Eno3
enolase 3
increases expression
ISO
salvin results in increased expression of ENO3 protein
CTD
PMID:35926579
NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
G
Fabp1
fatty acid binding protein 1
decreases expression
ISO
salvin results in decreased expression of FABP1 protein
CTD
PMID:35926579
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
G
Fabp5
fatty acid binding protein 5
decreases expression
ISO
salvin results in decreased expression of FABP5 protein
CTD
PMID:35926579
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
G
Fas
Fas cell surface death receptor
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of FAS protein]
CTD
PMID:29854073
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
G
Fbln2
fibulin 2
decreases expression
ISO
salvin results in decreased expression of FBLN2 protein
CTD
PMID:35926579
NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
G
Fen1
flap structure-specific endonuclease 1
decreases expression
ISO
salvin results in decreased expression of FEN1 protein
CTD
PMID:35926579
NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
G
Fga
fibrinogen alpha chain
decreases expression
ISO
salvin results in decreased expression of FGA protein
CTD
PMID:35926579
NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
G
Fgb
fibrinogen beta chain
decreases expression
ISO
salvin results in decreased expression of FGB protein
CTD
PMID:35926579
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
G
Fgf21
fibroblast growth factor 21
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of FGF21 mRNA]
CTD
PMID:35202923
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
G
Fgg
fibrinogen gamma chain
decreases expression
ISO
salvin results in decreased expression of FGG protein
CTD
PMID:35926579
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
G
Fis1
fission, mitochondrial 1
multiple interactions
ISO
salvin inhibits the reaction [Oxidopamine results in increased expression of FIS1 protein]
CTD
PMID:31705926
NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
G
Fmo2
flavin containing dimethylaniline monoxygenase 2
increases expression
ISO
salvin results in increased expression of FMO2 protein
CTD
PMID:35926579
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
G
Fscn1
fascin actin-bundling protein 1
decreases expression
ISO
salvin results in decreased expression of FSCN1 protein
CTD
PMID:35926579
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
G
Galnt12
polypeptide N-acetylgalactosaminyltransferase 12
decreases expression
ISO
salvin results in decreased expression of GALNT12 protein
CTD
PMID:35926579
NCBI chr 5:61,384,575...61,413,346
Ensembl chr 5:61,384,571...61,413,354
G
Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
decreases expression
ISO
salvin results in decreased expression of GALNT3 protein
CTD
PMID:35926579
NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
G
Garre1
granule associated Rac and RHOG effector 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of GARRE1 mRNA]
CTD
PMID:35202923
NCBI chr 1:86,862,121...86,939,725
Ensembl chr 1:86,862,121...86,939,687
G
Gc
GC, vitamin D binding protein
decreases expression
ISO
salvin results in decreased expression of GC protein
CTD
PMID:35926579
NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression multiple interactions
ISO EXP
salvin results in increased expression of GCLC mRNA salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLC protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLC protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLC protein]
CTD
PMID:18329808 PMID:25446857 PMID:26577515 PMID:26686574
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
multiple interactions increases expression
EXP ISO
salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLM protein]; salvin inhibits the reaction [Acrylamide results in decreased expression of GCLM mRNA]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein]
CTD
PMID:25446857 PMID:26577515 PMID:26686574 PMID:28159594
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gcnt3
glucosaminyl (N-acetyl) transferase 3, mucin type
decreases expression
ISO
salvin results in decreased expression of GCNT3 protein
CTD
PMID:35926579
NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
G
Gfer
growth factor, augmenter of liver regeneration
increases expression
ISO
salvin results in increased expression of GFER protein
CTD
PMID:35926579
NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
G
Ggh
gamma-glutamyl hydrolase
increases expression
ISO
salvin results in increased expression of GGH protein
CTD
PMID:35926579
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Glod5
glyoxalase domain containing 5
increases expression
ISO
salvin results in increased expression of GLOD5 protein
CTD
PMID:35926579
NCBI chr X:14,473,994...14,488,797
Ensembl chr X:14,473,994...14,488,683
G
Gnl3
G protein nucleolar 3
decreases expression
ISO
salvin results in decreased expression of GNL3 protein
CTD
PMID:35926579
NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of GPT protein]
CTD
PMID:29854073 PMID:35202923
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx1
glutathione peroxidase 1
multiple interactions
ISO
salvin inhibits the reaction [Acrylamide results in decreased expression of GPX1 mRNA]
CTD
PMID:28159594
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Grn
granulin precursor
decreases expression
ISO
salvin results in decreased expression of GRN protein
CTD
PMID:35926579
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
G
Gsdme
gasdermin E
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of GSDME mRNA]
CTD
PMID:35202923
NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
G
Gsr
glutathione-disulfide reductase
multiple interactions increases expression
EXP ISO
salvin inhibits the reaction [Oxidopamine results in decreased expression of GSR protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GSR protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSR protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GSR protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GSR protein] salvin inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD
PMID:25446857 PMID:26577515 PMID:26686574 PMID:29854073
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gstp1
glutathione S-transferase pi 1
multiple interactions increases expression
EXP ISO
salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GSTP1 protein]; GSTP1 mutant form inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein]]; GSTP1 mutant form inhibits the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSTP1 protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of GSTP1 protein]; salvin results in increased expression of and results in increased activity of GSTP1 protein
CTD
PMID:25271104 PMID:26577515
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gtf2f1
general transcription factor IIF subunit 1
decreases expression
ISO
salvin results in decreased expression of GTF2F1 protein
CTD
PMID:35926579
NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
decreases expression
ISO
salvin results in decreased expression of HMGCS2 protein
CTD
PMID:35926579
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
G
Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO
salvin results in increased expression of HMOX1 mRNA; salvin results in increased expression of HMOX1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of HMOX1 protein]
CTD
PMID:18329808 PMID:23942037 PMID:26686574
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
decreases expression
ISO
salvin results in decreased expression of HNRNPA3 protein
CTD
PMID:35926579
NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
G
Hp
haptoglobin
decreases expression
ISO
salvin results in decreased expression of HP protein
CTD
PMID:35926579
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
G
Hpx
hemopexin
decreases expression
ISO
salvin results in decreased expression of HPX protein
CTD
PMID:35926579
NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
G
Hsd17b6
hydroxysteroid (17-beta) dehydrogenase 6
decreases expression
ISO
salvin results in decreased expression of HSD17B6 protein
CTD
PMID:35926579
NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
G
Id3
inhibitor of DNA binding 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of ID3 mRNA]
CTD
PMID:35202923
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
G
Ifng
interferon gamma
multiple interactions
ISO
salvin inhibits the reaction [IFNG protein results in increased abundance of Nitrites]
CTD
PMID:23942037
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Igfbp7
insulin-like growth factor binding protein 7
decreases expression
ISO
salvin results in decreased expression of IGFBP7 protein
CTD
PMID:35926579
NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
G
Igkvl-ps13
immunoglobulin kappa variable like, pseudogene 13
decreases expression
ISO
salvin results in decreased expression of IGKV1-133 protein
CTD
PMID:35926579
NCBI chr 4:96,968,574...96,969,477
G
Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
multiple interactions increases ubiquitination
ISO
PRKN protein affects the reaction [salvin results in increased ubiquitination of IKBKG protein]
CTD
PMID:31705926
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
G
Inhbe
inhibin subunit beta E
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of INHBE mRNA]
CTD
PMID:35202923
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Inmt
indolethylamine N-methyltransferase
increases expression
ISO
salvin results in increased expression of INMT protein
CTD
PMID:35926579
NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
G
Ints3
integrator complex subunit 3
decreases expression
ISO
salvin results in decreased expression of INTS3 protein
CTD
PMID:35926579
NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709
G
Itga2
integrin subunit alpha 2
decreases expression
ISO
salvin results in decreased expression of ITGA2 protein
CTD
PMID:35926579
NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
G
Itgam
integrin subunit alpha M
multiple interactions decreases expression
ISO
[salvin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGAM protein; salvin promotes the reaction [Calcitriol results in increased expression of ITGAM protein]; salvin promotes the reaction [Tretinoin results in increased expression of ITGAM protein] salvin results in decreased expression of ITGAM protein
CTD
PMID:11504768 PMID:35926579
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
G
Itgb2
integrin subunit beta 2
decreases expression
ISO
salvin results in decreased expression of ITGB2 protein
CTD
PMID:35926579
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
G
Klf12
KLF transcription factor 12
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of KLF12 mRNA]
CTD
PMID:35202923
NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
G
Kng1
kininogen 1
decreases expression
ISO
salvin results in decreased expression of KNG1 protein
CTD
PMID:35926579
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
G
Lamp2
lysosomal-associated membrane protein 2
decreases expression
ISO
salvin results in decreased expression of LAMP2 protein
CTD
PMID:35926579
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lcn2
lipocalin 2
decreases expression
ISO
salvin results in decreased expression of LCN2 protein
CTD
PMID:35926579
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
G
Lgals2
galectin 2
decreases expression
ISO
salvin results in decreased expression of LGALS2 protein
CTD
PMID:35926579
NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802
G
Lgals3bp
galectin 3 binding protein
decreases expression
ISO
salvin results in decreased expression of LGALS3BP protein
CTD
PMID:35926579
NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
G
Lgals9
galectin 9
decreases expression
ISO
salvin results in decreased expression of LGALS9 protein
CTD
PMID:35926579
NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
G
Lgmn
legumain
decreases expression
ISO
salvin results in decreased expression of LGMN protein
CTD
PMID:35926579
NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
G
Ltf
lactotransferrin
decreases expression
ISO
salvin results in decreased expression of LTF protein
CTD
PMID:35926579
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
G
Luzp1
leucine zipper protein 1
decreases expression
ISO
salvin results in decreased expression of LUZP1 protein
CTD
PMID:35926579
NCBI chr 5:148,706,094...148,781,616
Ensembl chr 5:148,706,138...148,781,609
G
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
increases expression
ISO
salvin results in increased expression of LYVE1 protein
CTD
PMID:35926579
NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309
G
Lyz2
lysozyme 2
decreases expression
ISO
salvin results in decreased expression of LYZ2 protein
CTD
PMID:35926579
NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
EXP ISO
salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]
CTD
PMID:25446857 PMID:29854073
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
G
Mapk9
mitogen-activated protein kinase 9
multiple interactions
EXP
salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK9 protein]
CTD
PMID:25446857
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
G
Marcksl1
MARCKS-like 1
decreases expression
ISO
salvin results in decreased expression of MARCKSL1 protein
CTD
PMID:35926579
NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817
G
Mcm7
minichromosome maintenance complex component 7
decreases expression
ISO
salvin results in decreased expression of MCM7 protein
CTD
PMID:35926579
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
G
Mfn2
mitofusin 2
multiple interactions
ISO
salvin inhibits the reaction [Oxidopamine results in decreased expression of MFN2 protein]
CTD
PMID:31705926
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
G
Mov10
Mov10 RNA helicase
decreases expression
ISO
salvin results in decreased expression of MOV10 protein
CTD
PMID:35926579
NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083
G
Mpo
myeloperoxidase
decreases expression
ISO
salvin results in decreased expression of MPO protein
CTD
PMID:35926579
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
G
Mpzl2
myelin protein zero-like 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of MPZL2 mRNA]
CTD
PMID:35202923
NCBI chr 8:45,348,285...45,359,298
Ensembl chr 8:45,348,285...45,359,298
G
Mrps31
mitochondrial ribosomal protein S31
decreases expression
ISO
salvin results in decreased expression of MRPS31 protein
CTD
PMID:35926579
NCBI chr16:69,601,349...69,621,609
Ensembl chr16:69,601,349...69,630,654
G
Mtor
mechanistic target of rapamycin kinase
decreases phosphorylation
ISO
salvin results in decreased phosphorylation of MTOR protein
CTD
PMID:25178877 PMID:28918123
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Mug1
murinoglobulin 1
decreases expression
ISO
salvin results in decreased expression of MUG1 protein
CTD
PMID:35926579
NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
G
Mug2
murinoglobulin 2
decreases expression
ISO
salvin results in decreased expression of MUG2 protein
CTD
PMID:35926579
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
G
Mylip
myosin regulatory light chain interacting protein
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of MYLIP mRNA]
CTD
PMID:35202923
NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
G
Myo1b
myosin Ib
decreases expression
ISO
salvin results in decreased expression of MYO1B protein
CTD
PMID:35926579
NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
G
Ndst1
N-deacetylase and N-sulfotransferase 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of NDST1 mRNA]
CTD
PMID:35202923
NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
G
Ndufa12
NADH:ubiquinone oxidoreductase subunit A12
increases expression
ISO
salvin results in increased expression of NDUFA12 protein
CTD
PMID:35926579
NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315
G
Nelfb
negative elongation factor complex member B
decreases expression
ISO
salvin results in decreased expression of NELFB protein
CTD
PMID:35926579
NCBI chr 3:8,010,883...8,027,403
Ensembl chr 3:8,010,888...8,027,403
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity multiple interactions
ISO
salvin results in increased activity of NFE2L2 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased activity of NFE2L2 protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSR protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of GSTP1 protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of SOD2 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLC protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GCLM protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of GSR protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of SOD2 protein]; salvin affects the localization of and results in increased activity of NFE2L2 protein; salvin inhibits the reaction [Acrylamide results in decreased expression of NFE2L2 mRNA]; salvin inhibits the reaction [Acrylamide results in decreased expression of NFE2L2 protein]
CTD
PMID:26577515 PMID:26686574 PMID:28159594
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of NFKBIA protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased phosphorylation of NFKBIA protein]; salvin results in increased phosphorylation of and results in increased degradation of NFKBIA protein
CTD
PMID:21375325 PMID:25271104 PMID:29854073
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Nlrp12
NLR family, pyrin domain containing 12
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of NLRP12 mRNA]
CTD
PMID:35202923
NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD
PMID:21375325
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nox1
NADPH oxidase 1
decreases expression
ISO
salvin results in decreased expression of NOX1 protein
CTD
PMID:35926579
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression multiple interactions
ISO
salvin results in increased expression of NQO1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of NQO1 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of NQO1 protein]; salvin inhibits the reaction [Acrylamide results in decreased expression of NQO1 mRNA]
CTD
PMID:18329808 PMID:26686574 PMID:28159594
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr3c2
nuclear receptor subfamily 3, group C, member 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of NR3C2 mRNA]
CTD
PMID:35202923
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
G
Nrdc
nardilysin convertase
decreases expression
ISO
salvin results in decreased expression of NRDC protein
CTD
PMID:35926579
NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595
G
Oas1a
2'-5' oligoadenylate synthetase 1A
increases expression
ISO
salvin results in increased expression of OAS1G protein
CTD
PMID:35926579
NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
G
Opa1
OPA1, mitochondrial dynamin like GTPase
multiple interactions increases expression
ISO
OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; PRKN protein affects the reaction [salvin results in increased expression of OPA1 protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of OPA1 protein]
CTD
PMID:31705926
NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
G
Orm1
orosomucoid 1
decreases expression
ISO
salvin results in decreased expression of ORM1 protein
CTD
PMID:35926579
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases cleavage decreases expression
ISO EXP
Acetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein]; OPA1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein] salvin results in decreased expression of PARP1 protein
CTD
PMID:25446857 PMID:28918123 PMID:30707903 PMID:31705926
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Pcbd2
pterin-4 alpha-carbinolamine dehydratase 2
increases expression
ISO
salvin results in increased expression of PCBD2 protein
CTD
PMID:35926579
NCBI chr17:8,845,161...8,896,343
Ensembl chr17:8,845,084...8,910,539
G
Pde5a
phosphodiesterase 5A
increases expression
ISO
salvin results in increased expression of PDE5A protein
CTD
PMID:35926579
NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
G
Per2
period circadian regulator 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of PER2 mRNA]
CTD
PMID:35202923
NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
G
Pgam5
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
decreases expression
ISO
salvin results in decreased expression of PGAM5 protein
CTD
PMID:35926579
NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
G
Pglyrp1
peptidoglycan recognition protein 1
decreases expression
ISO
salvin results in decreased expression of PGLYRP1 protein
CTD
PMID:35926579
NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001
G
Phgdh
phosphoglycerate dehydrogenase
decreases expression
ISO
salvin results in decreased expression of PHGDH protein
CTD
PMID:35926579
NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
G
Pink1
PTEN induced kinase 1
multiple interactions
ISO
PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of BCL2 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of VDAC1 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of CASP3 protein]]; PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]]; salvin inhibits the reaction [Oxidopamine results in decreased expression of PINK1 protein]
CTD
PMID:30707903
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
G
Plg
plasminogen
decreases expression
ISO
salvin results in decreased expression of PLG protein
CTD
PMID:35926579
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
G
Plin2
perilipin 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of PLIN2 mRNA]
CTD
PMID:35202923
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Plin4
perilipin 4
increases expression
ISO
salvin results in increased expression of PLIN4 protein
CTD
PMID:35926579
NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
G
Plpp1
phospholipid phosphatase 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of PLPP1 mRNA]
CTD
PMID:35202923
NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268
G
Pnlip
pancreatic lipase
decreases expression
ISO
salvin results in decreased expression of PNLIP protein
CTD
PMID:35926579
NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
G
Pnliprp1
pancreatic lipase-related protein 1
decreases expression
ISO
salvin results in decreased expression of PNLIPRP1 protein
CTD
PMID:35926579
NCBI chr 1:257,867,885...257,883,514
Ensembl chr 1:257,867,885...257,883,514
G
Pparg
peroxisome proliferator-activated receptor gamma
increases activity
ISO
salvin results in increased activity of PPARG protein
CTD
PMID:20696231
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Prdx6
peroxiredoxin 6
increases expression
ISO
salvin results in increased expression of PRDX6 protein
CTD
PMID:35926579
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
G
Prkn
parkin RBR E3 ubiquitin protein ligase
multiple interactions increases expression
ISO
PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]]; PRKN protein affects the reaction [salvin results in increased expression of OPA1 protein]; PRKN protein affects the reaction [salvin results in increased expression of RELA protein]; PRKN protein affects the reaction [salvin results in increased ubiquitination of IKBKG protein]; salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein] salvin results in increased expression of PRKN protein
CTD
PMID:30707903 PMID:31705926
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
G
Prom1
prominin 1
decreases expression
ISO
salvin results in decreased expression of PROM1 protein
CTD
PMID:35926579
NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
G
Pten
phosphatase and tensin homolog
multiple interactions increases expression
ISO
salvin promotes the reaction [arsenic trioxide results in increased expression of PTEN mRNA] salvin results in increased expression of PTEN mRNA
CTD
PMID:23239002
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
G
Ptgds
prostaglandin D2 synthase
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of PTGDS mRNA]
CTD
PMID:35202923
NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD
PMID:21375325
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Pvalb
parvalbumin
decreases expression
ISO
salvin results in decreased expression of PVALB protein
CTD
PMID:35926579
NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
G
Pxdn
peroxidasin
decreases expression
ISO
salvin results in decreased expression of PXDN protein
CTD
PMID:35926579
NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345
G
Qsox1
quiescin sulfhydryl oxidase 1
decreases expression
ISO
salvin results in decreased expression of QSOX1 protein
CTD
PMID:35926579
NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
G
Rab11fip2
RAB11 family interacting protein 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of RAB11FIP2 mRNA]
CTD
PMID:35202923
NCBI chr 1:258,950,535...259,094,555
Ensembl chr 1:258,923,873...259,093,752
G
Rapgef5
Rap guanine nucleotide exchange factor 5
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of RAPGEF5 mRNA]
CTD
PMID:35202923
NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936
G
Rara
retinoic acid receptor, alpha
multiple interactions
ISO
[Tetradecanoylphorbol Acetate co-treated with salvin] results in increased expression of RARA protein
CTD
PMID:11504768
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
G
Rbpms
RNA binding protein, mRNA processing factor
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of RBPMS mRNA]
CTD
PMID:35202923
NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
G
Rdh9
retinol dehydrogenase 9
decreases expression
ISO
salvin results in decreased expression of RDH9 protein
CTD
PMID:35926579
NCBI chr 7:63,642,305...63,645,149
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions affects localization increases expression
ISO
salvin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of and affects the localization of RELA protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin affects the localization of RELA protein]; PRKN protein affects the reaction [salvin results in increased expression of RELA protein]; salvin results in increased expression of and results in increased activity of RELA protein
CTD
PMID:21375325 PMID:25271104 PMID:29854073 PMID:31705926
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rer1
retention in endoplasmic reticulum sorting receptor 1
increases expression
ISO
salvin results in increased expression of RER1 protein
CTD
PMID:35926579
NCBI chr 5:165,634,567...165,646,643
Ensembl chr 5:165,634,300...165,646,750
G
Rheb
Ras homolog, mTORC1 binding
decreases expression
ISO
salvin results in decreased expression of RHEB protein
CTD
PMID:35926579
NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
G
Rnase4
ribonuclease A family member 4
decreases expression
ISO
salvin results in decreased expression of RNASE4 protein
CTD
PMID:35926579
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
G
Rpa1
replication protein A1
decreases expression
ISO
salvin results in decreased expression of RPA1 protein
CTD
PMID:35926579
NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949
G
Rps21-ps1
ribosomal protein S21, pseudogene 1
increases expression
ISO
salvin results in increased expression of RPS21 protein
CTD
PMID:35926579
NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427
G
Rxra
retinoid X receptor alpha
increases expression multiple interactions
ISO
salvin results in increased expression of RXRA protein Calcitriol promotes the reaction [salvin results in increased expression of RXRA protein]; Tretinoin promotes the reaction [salvin results in increased expression of RXRA protein]
CTD
PMID:11504768
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
G
S100a11
S100 calcium binding protein A11
decreases expression
ISO
salvin results in decreased expression of S100A11 protein
CTD
PMID:35926579
NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
G
S100a8
S100 calcium binding protein A8
decreases expression
ISO
salvin results in decreased expression of S100A8 protein
CTD
PMID:35926579
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
G
S100a9
S100 calcium binding protein A9
decreases expression
ISO
salvin results in decreased expression of S100A9 protein
CTD
PMID:35926579
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
G
S100g
S100 calcium binding protein G
increases expression
ISO
salvin results in increased expression of S100G protein
CTD
PMID:35926579
NCBI chr X:31,705,853...31,708,422
Ensembl chr X:31,705,866...31,708,433
G
Sdc3
syndecan 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of SDC3 mRNA]
CTD
PMID:35202923
NCBI chr 5:142,965,659...142,998,390
Ensembl chr 5:142,965,591...142,996,480
G
Serpina3n
serpin family A member 3N
decreases expression
ISO
salvin results in decreased expression of SERPINA3N protein
CTD
PMID:35926579
NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
G
Sgsm3
small G protein signaling modulator 3
decreases expression
ISO
salvin results in decreased expression of SGSM3 protein
CTD
PMID:35926579
NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:112,514,630...112,544,108
G
Shc1
SHC adaptor protein 1
multiple interactions decreases expression increases expression
ISO
salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased expression of SHC1 protein]; SIRT1 mutant form inhibits the reaction [salvin results in decreased expression of SHC1 protein] salvin results in increased expression of SHC1 mRNA
CTD
PMID:24557422
NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
G
Shmt2
serine hydroxymethyltransferase 2
decreases expression
ISO
salvin results in decreased expression of SHMT2 protein
CTD
PMID:35926579
NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
G
Sik2
salt-inducible kinase 2
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of SIK2 mRNA]
CTD
PMID:35202923
NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415
G
Sirt1
sirtuin 1
multiple interactions increases expression
ISO
Niacinamide inhibits the reaction [salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SIRT1 protein]]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SIRT1 protein]; SIRT1 mutant form inhibits the reaction [salvin results in decreased expression of SHC1 protein] salvin results in increased expression of SIRT1 mRNA; salvin results in increased expression of SIRT1 protein
CTD
PMID:24557422
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
G
Slc26a3
solute carrier family 26 member 3
increases expression
ISO
salvin results in increased expression of SLC26A3 protein
CTD
PMID:35926579
NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772
G
Slc35a2
solute carrier family 35 member A2
increases expression
ISO
salvin results in increased expression of SLC35A2 protein
CTD
PMID:35926579
NCBI chr X:14,608,145...14,616,937
Ensembl chr X:14,608,055...14,616,678
G
Sltm
SAFB-like, transcription modulator
decreases expression
ISO
salvin results in decreased expression of SLTM protein
CTD
PMID:35926579
NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825
G
Snw1
SNW domain containing 1
decreases expression
ISO
salvin results in decreased expression of SNW1 protein
CTD
PMID:35926579
NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
G
Snx4
sorting nexin 4
decreases expression
ISO
salvin results in decreased expression of SNX4 protein
CTD
PMID:35926579
NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174
G
Sod1
superoxide dismutase 1
multiple interactions
ISO EXP
salvin inhibits the reaction [Acrylamide results in decreased expression of SOD1 mRNA]; salvin inhibits the reaction [Oxidopamine results in decreased expression of SOD1 protein]
CTD
PMID:25446857 PMID:28159594
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sod2
superoxide dismutase 2
multiple interactions increases expression
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of SOD2 protein]; NFE2L2 mutant form inhibits the reaction [salvin results in increased expression of SOD2 protein]; NFE2L2 protein promotes the reaction [salvin results in increased expression of SOD2 protein]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SOD2 protein]
CTD
PMID:24557422 PMID:26577515 PMID:26686574
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Sorbs1
sorbin and SH3 domain containing 1
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in decreased expression of SORBS1 mRNA]
CTD
PMID:35202923
NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
G
Sparc
secreted protein acidic and cysteine rich
decreases expression
ISO
salvin results in decreased expression of SPARC protein
CTD
PMID:35926579
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
G
Sprr2a
small proline rich protein 2A
decreases expression
ISO
salvin results in decreased expression of SPRR2A protein
CTD
PMID:35926579
NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236
G
Stub1
STIP1 homology and U-box containing protein 1
decreases expression
ISO
salvin results in decreased expression of STUB1 protein
CTD
PMID:35926579
NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
G
Tbx3
T-box transcription factor 3
multiple interactions
ISO
salvin inhibits the reaction [sodium arsenite results in increased expression of TBX3 mRNA]
CTD
PMID:35202923
NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
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Tep1
telomerase associated protein 1
decreases expression
ISO
salvin results in decreased expression of TEP1 protein
CTD
PMID:35926579
NCBI chr15:24,045,876...24,093,526
Ensembl chr15:24,045,878...24,093,526
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Tf
transferrin
decreases expression
ISO
salvin results in decreased expression of TF protein
CTD
PMID:35926579
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tgm3
transglutaminase 3
increases expression
ISO
salvin results in increased expression of TGM3 protein
CTD
PMID:35926579
NCBI chr 3:117,228,661...117,264,078
Ensembl chr 3:117,228,661...117,264,075
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Th
tyrosine hydroxylase
multiple interactions
EXP
salvin inhibits the reaction [Oxidopamine results in decreased expression of TH protein]
CTD
PMID:25446857
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Tinagl1
tubulointerstitial nephritis antigen-like 1
increases expression
ISO
salvin results in increased expression of TINAGL1 protein
CTD
PMID:35926579
NCBI chr 5:142,513,710...142,523,730
Ensembl chr 5:142,513,714...142,523,720
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Tmed5
transmembrane p24 trafficking protein 5
decreases expression
ISO
salvin results in decreased expression of TMED5 protein
CTD
PMID:35926579
NCBI chr14:1,607,895...1,619,028
Ensembl chr14:1,607,819...1,628,426
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Tmsb4x
thymosin beta 4, X-linked
decreases expression
ISO
salvin results in decreased expression of TMSB4X protein
CTD
PMID:35926579
NCBI chr X:27,144,666...27,146,667
Ensembl chr X:27,128,610...27,146,667
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Tnf
tumor necrosis factor
multiple interactions
ISO
salvin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD
PMID:21375325
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnxb
tenascin XB
increases expression
ISO
salvin results in increased expression of TNXB protein
CTD
PMID:35926579
G
Tsg101
tumor susceptibility 101
decreases expression
ISO
salvin results in decreased expression of TSG101 protein
CTD
PMID:35926579
NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
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Tspan15
tetraspanin 15
increases expression
ISO
salvin results in increased expression of TSPAN15 protein
CTD
PMID:35926579
NCBI chr20:30,130,528...30,174,912
Ensembl chr20:30,130,530...30,174,930
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Txlna
taxilin alpha
decreases expression
ISO
salvin results in decreased expression of TXLNA protein
CTD
PMID:35926579
NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583
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Tyr
tyrosinase
decreases expression
ISO
salvin results in decreased expression of TYR mRNA
CTD
PMID:21071833
NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
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Ubl4a
ubiquitin-like 4A
decreases expression
ISO
salvin results in decreased expression of UBL4A protein
CTD
PMID:35926579
NCBI chr X:152,151,242...152,154,094
Ensembl chr X:152,151,460...152,154,069
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Vdac1
voltage-dependent anion channel 1
multiple interactions
ISO
PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of VDAC1 protein]]; salvin inhibits the reaction [Oxidopamine results in decreased expression of and results in decreased ubiquitination of VDAC1 protein]
CTD
PMID:30707903
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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Vdr
vitamin D receptor
multiple interactions increases expression
ISO
Calcitriol promotes the reaction [salvin results in increased expression of VDR protein]; Tetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein]; Tretinoin promotes the reaction [salvin results in increased expression of VDR protein]
CTD
PMID:11504768
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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Vill
villin-like
decreases expression
ISO
salvin results in decreased expression of VILL protein
CTD
PMID:35926579
NCBI chr 8:118,776,718...118,794,983
Ensembl chr 8:118,776,742...118,794,983
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Wdr5
WD repeat domain 5
decreases expression
ISO
salvin results in decreased expression of WDR5 protein
CTD
PMID:35926579
NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671
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Wif1
Wnt inhibitory factor 1
decreases expression
ISO
salvin results in decreased expression of WIF1 protein
CTD
PMID:35926579
NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360
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Zfp207
zinc finger protein 207
decreases expression
ISO
salvin results in decreased expression of ZFP207 protein; salvin results in decreased expression of ZNF207 protein
CTD
PMID:35926579
NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
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