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ONTOLOGY REPORT - ANNOTATIONS


Term:corticotropin-releasing hormone
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Accession:CHEBI:65311 term browser browse the term
Definition:A family of peptide hormones derived from a 191-membered prehormone, secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. The first full sequence was discovered in sheep, those in rats and humans differ from the ovine sequence by 7 amino acids.
Synonyms:related_synonym: CRH;   corticotropin-releasing factor
 xref_mesh: MESH:D003346
 xref: PMID:22494987 "Europe PMC";   PMID:6267699 "Europe PMC";   Wikipedia:Corticotropin-releasing_hormone


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corticotropin-releasing hormone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        molecular messenger 18135
          neurotransmitter 6084
            corticotropin-releasing hormone 1
              corticotropin-releasing hormone (human) 0
              corticotropin-releasing hormone (ovine) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                peptide 9320
                                                  polypeptide 184
                                                    corticotropin-releasing hormone 1
                                                      corticotropin-releasing hormone (human) 0
                                                      corticotropin-releasing hormone (ovine) 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.