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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antacid
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Accession:CHEBI:65265 term browser browse the term
Definition:Any substance which is used to neutralise stomach acidity.
Synonyms:related_synonym: antacids
 xref: Wikipedia:Antacid



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aluminium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP Aluminum Hydroxide results in decreased expression of ABCC2 protein CTD PMID:14976346 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of ACTA2 protein; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of ACTA2 protein] CTD PMID:35481609 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of AKT1 protein; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of AKT1 protein] CTD PMID:35481609 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased activity of CASP1 protein]; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased expression of and results in increased secretion of CASP1 protein modified form]; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 PMID:22075093 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Cat catalase decreases activity EXP Aluminum Hydroxide results in decreased activity of CAT protein CTD PMID:14976346 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO Aluminum Hydroxide results in increased secretion of CCL2 protein CTD PMID:18390722 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO Aluminum Hydroxide results in increased secretion of CCL3 protein CTD PMID:18390722 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO Aluminum Hydroxide results in increased secretion of CCL4 protein CTD PMID:18390722 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion ISO Aluminum Hydroxide results in increased secretion of CCL5 protein CTD PMID:18390722 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO Aluminum Hydroxide promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CCR7 protein] CTD PMID:18390722 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Aluminum Hydroxide results in decreased expression of CD14 protein CTD PMID:18390722 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd4 Cd4 molecule affects response to substance ISO CD4 protein affects the susceptibility to Aluminum Hydroxide CTD PMID:11160013 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd40 CD40 molecule increases expression ISO Aluminum Hydroxide results in increased expression of CD40 protein CTD PMID:11160013 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Aluminum Hydroxide inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD80 protein] CTD PMID:18390722 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd83 CD83 molecule increases expression ISO Aluminum Hydroxide results in increased expression of CD83 protein CTD PMID:11160013 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cd86 CD86 molecule increases expression
multiple interactions
ISO Aluminum Hydroxide results in increased expression of CD86 protein
Aluminum Hydroxide promotes the reaction [CSF2 protein results in increased expression of CD86 protein]
CTD PMID:11160013 PMID:18390722 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Aluminum Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Aluminum Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Crlf2 cytokine receptor-like factor 2 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of CRLF2 mRNA; [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of CRLF2 protein; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of CRLF2 mRNA]; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of CRLF2 protein] CTD PMID:36029577 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Aluminum Hydroxide inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD1A protein]; Aluminum Hydroxide inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD80 protein]; Aluminum Hydroxide promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CCR7 protein]; Aluminum Hydroxide promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of TFRC protein]; Aluminum Hydroxide promotes the reaction [CSF2 protein results in increased expression of CD86 protein] CTD PMID:18390722 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein] CTD PMID:17404311 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of EGFR mRNA; cang er zi wan affects the reaction [[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of EGFR mRNA] CTD PMID:36855022 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of GATA3 mRNA; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of GATA3 mRNA] CTD PMID:36029577 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Aluminum Hydroxide results in increased expression of ICAM1 protein CTD PMID:11160013 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il13 interleukin 13 increases expression
multiple interactions
ISO Aluminum Hydroxide results in increased expression of IL13 mRNA
[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of IL13 protein; [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL13 protein; cang er zi wan affects the reaction [[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of IL13 protein]; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL13 protein]; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL13 protein]
CTD PMID:9328138 PMID:35481609 PMID:36029577 PMID:36855022 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein]
[[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]
CTD PMID:17404311 PMID:18604214 PMID:22075093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases secretion ISO Aluminum Hydroxide results in increased secretion of IL1RN protein CTD PMID:18390722 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 increases expression
multiple interactions
ISO Aluminum Hydroxide results in increased expression of IL2 mRNA
[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]; TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]
CTD PMID:9328138 PMID:22075093 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions
affects response to substance
ISO Aluminum Hydroxide results in increased expression of IL4 mRNA
[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of IL4 protein; [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL4 protein; cang er zi wan affects the reaction [[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of IL4 protein]; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL4 protein]; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL4 protein]; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL4 protein]
IL4 protein affects the susceptibility to Aluminum Hydroxide
Aluminum Hydroxide inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD1A protein]; Aluminum Hydroxide inhibits the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CD80 protein]; Aluminum Hydroxide promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of CCR7 protein]; Aluminum Hydroxide promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of TFRC protein]
CTD PMID:9328138 PMID:11160013 PMID:18390722 PMID:35481609 PMID:36029577 More... NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 increases expression
multiple interactions
ISO Aluminum Hydroxide results in increased expression of IL5 mRNA
[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of IL5 protein; [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL5 protein; cang er zi wan affects the reaction [[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of IL5 protein]; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL5 protein]; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL5 protein]; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL5 protein]
CTD PMID:9328138 PMID:35481609 PMID:36029577 PMID:36855022 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 increases expression ISO Aluminum Hydroxide results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7r interleukin 7 receptor multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL7R mRNA; [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL7R protein; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL7R mRNA]; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of IL7R protein] CTD PMID:36029577 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK1 protein; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK1 protein] CTD PMID:36029577 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK2 protein; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of JAK2 protein] CTD PMID:36029577 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of MAPK3 mRNA; cang er zi wan affects the reaction [[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of MAPK3 mRNA] CTD PMID:36855022 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of MUC5AC mRNA; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of MUC5AC mRNA] CTD PMID:35481609 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of PTGS2 mRNA; cang er zi wan affects the reaction [[Aluminum Hydroxide co-treated with Ovalbumin] affects the expression of PTGS2 mRNA] CTD PMID:36855022 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of STAT3 protein; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased phosphorylation of STAT3 protein] CTD PMID:36029577 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tfrc transferrin receptor multiple interactions ISO Aluminum Hydroxide promotes the reaction [[CSF2 protein co-treated with IL4 protein] results in increased expression of TFRC protein] CTD PMID:18390722 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TGFB1 protein; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TGFB1 protein] CTD PMID:35481609 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]; TLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]; TLR4 protein affects the susceptibility to [Aluminum Hydroxide co-treated with Magnesium Hydroxide] CTD PMID:22075093 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNF protein; Dexamethasone inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNF protein]; dioscin inhibits the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNF protein] CTD PMID:35481609 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNFRSF4 mRNA; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNFRSF4 mRNA] CTD PMID:36029577 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
JBrowse link
G Tnfsf4 TNF superfamily member 4 multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNFSF4 mRNA; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TNFSF4 mRNA] CTD PMID:36029577 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TSLP mRNA; [Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TSLP protein; nonylphenol promotes the reaction [[Ovalbumin co-treated with Aluminum Hydroxide] results in increased expression of TSLP protein] CTD PMID:36029577 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
calcium carbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Calcium Carbonate results in decreased expression of BGLAP protein CTD PMID:2027271 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Capn1 calpain 1 increases activity ISO Calcium Carbonate analog results in increased activity of CAPN1 protein CTD PMID:24412303 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Casp3 caspase 3 increases activity ISO Calcium Carbonate analog results in increased activity of CASP3 protein CTD PMID:24412303 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Calcium Carbonate analog results in increased expression of DDIT3 CTD PMID:24412303 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Pth parathyroid hormone affects expression
decreases expression
ISO Calcium Carbonate affects the expression of PTH protein
Calcium Carbonate results in decreased expression of PTH protein
CTD PMID:1752077 PMID:2027271 PMID:3826069 PMID:7891547 PMID:8481062 More... NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Calcium Carbonate results in decreased expression of PTHLH protein CTD PMID:16006300 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO Calcium Carbonate results in decreased expression of SPP1 protein CTD PMID:17977878 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
calcium silicate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO calcium silicate results in increased expression of ADIPOQ mRNA CTD PMID:29279043 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Alb albumin increases expression ISO calcium silicate results in increased expression of ALB mRNA CTD PMID:29279043 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO calcium silicate results in increased expression of AMBP mRNA CTD PMID:29279043 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G Ankrd39 ankyrin repeat domain 39 increases expression ISO calcium silicate results in increased expression of ANKRD39 mRNA CTD PMID:29279043 NCBI chr 9:38,780,291...38,790,177
Ensembl chr 9:38,781,785...38,790,201
JBrowse link
G Aoah acyloxyacyl hydrolase increases expression ISO calcium silicate results in increased expression of AOAH mRNA CTD PMID:29279043 NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148
JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO calcium silicate results in increased expression of APOA2 mRNA CTD PMID:29279043 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apob apolipoprotein B increases expression ISO calcium silicate results in increased expression of APOB mRNA CTD PMID:29279043 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression ISO calcium silicate results in decreased expression of ARMCX2 mRNA CTD PMID:29279043 NCBI chr  X:97,980,662...97,985,523
Ensembl chr  X:97,980,660...97,985,552
JBrowse link
G Aste1 asteroid homolog 1 increases expression ISO calcium silicate results in increased expression of ASTE1 mRNA CTD PMID:29279043 NCBI chr 8:106,026,570...106,044,694
Ensembl chr 8:106,026,515...106,044,430
JBrowse link
G Bcl9l BCL9 like decreases expression ISO calcium silicate results in decreased expression of BCL9L mRNA CTD PMID:29279043 NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611
JBrowse link
G Bgn biglycan decreases expression ISO calcium silicate results in decreased expression of BGN mRNA CTD PMID:29279043 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression ISO calcium silicate results in increased expression of BMAL1 mRNA CTD PMID:29279043 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO calcium silicate results in decreased expression of BPTF mRNA CTD PMID:29279043 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO calcium silicate results in decreased expression of CAPNS1 mRNA CTD PMID:29279043 NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795
JBrowse link
G Car3 carbonic anhydrase 3 increases expression ISO calcium silicate results in increased expression of CAR3 mRNA CTD PMID:29279043 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP calcium silicate results in increased expression of CCL2 protein CTD PMID:16601788 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression EXP calcium silicate results in increased expression of CCL3 protein CTD PMID:16601788 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO calcium silicate results in increased expression of CHRNB3 mRNA CTD PMID:29279043 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO calcium silicate results in increased expression of CLCA1 mRNA CTD PMID:29279043 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of COL1A1 mRNA CTD PMID:23483914 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO calcium silicate results in increased expression of CYBB mRNA CTD PMID:29279043 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Ddo D-aspartate oxidase decreases expression ISO calcium silicate results in decreased expression of DDO mRNA CTD PMID:29279043 NCBI chr20:44,090,823...44,109,962
Ensembl chr20:44,090,914...44,133,095
JBrowse link
G Dhx35 DEAH-box helicase 35 increases expression ISO calcium silicate results in increased expression of DHX35 mRNA CTD PMID:29279043 NCBI chr 3:147,450,178...147,507,473
Ensembl chr 3:147,450,163...147,507,451
JBrowse link
G Dpp10 dipeptidyl peptidase like 10 increases expression ISO calcium silicate results in increased expression of DPP10 mRNA CTD PMID:29279043 NCBI chr13:34,584,420...36,269,292
Ensembl chr13:34,595,868...36,269,292
JBrowse link
G Egfr epidermal growth factor receptor increases activity ISO calcium silicate results in increased activity of EGFR protein CTD PMID:21762757 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 increases expression ISO calcium silicate results in increased expression of EPB42 mRNA CTD PMID:29279043 NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932
JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression ISO calcium silicate results in increased expression of FAM83H mRNA CTD PMID:29279043 NCBI chr 7:107,716,431...107,724,619
Ensembl chr 7:107,716,431...107,728,672
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO calcium silicate results in increased expression of FGG mRNA CTD PMID:29279043 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO calcium silicate results in increased expression of FGL1 mRNA CTD PMID:29279043 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases secretion
ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of FLT1 protein] CTD PMID:21762757 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Gc GC, vitamin D binding protein increases expression ISO calcium silicate results in increased expression of GC mRNA CTD PMID:29279043 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Glt8d1 glycosyltransferase 8 domain containing 1 increases expression ISO calcium silicate results in increased expression of GLT8D1 mRNA CTD PMID:29279043 NCBI chr16:6,192,269...6,207,227
Ensembl chr16:6,192,300...6,207,229
JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP calcium silicate results in increased activity of GSR protein CTD PMID:16601788 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression ISO calcium silicate results in decreased expression of H1F2 mRNA CTD PMID:29279043 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO calcium silicate results in decreased expression of HLF mRNA CTD PMID:29279043 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmg20b high mobility group 20 B decreases expression ISO calcium silicate results in decreased expression of HMG20B mRNA CTD PMID:29279043 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640
JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression ISO calcium silicate results in increased expression of HPCAL1 mRNA CTD PMID:29279043 NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of IGF1 mRNA CTD PMID:23483914 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
ISO Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; prolinedithiocarbamate inhibits the reaction [calcium silicate results in increased secretion of IL6 protein] CTD PMID:21762757 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression ISO calcium silicate results in decreased expression of IPMK mRNA CTD PMID:29279043 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 decreases expression ISO calcium silicate results in decreased expression of KANK4 mRNA CTD PMID:29279043 NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555
JBrowse link
G Kat8 lysine acetyltransferase 8 increases expression ISO calcium silicate results in increased expression of KAT8 mRNA CTD PMID:29279043 NCBI chr 1:182,524,355...182,536,638
Ensembl chr 1:182,515,327...182,536,633
JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 decreases expression ISO calcium silicate results in decreased expression of KCNMB4 mRNA CTD PMID:29279043 NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278
JBrowse link
G Kdr kinase insert domain receptor increases secretion ISO calcium silicate results in increased secretion of KDR protein CTD PMID:21762757 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Klhl2 kelch-like family member 2 decreases expression ISO calcium silicate results in decreased expression of KLHL2 mRNA CTD PMID:29279043 NCBI chr16:24,860,744...24,973,348
Ensembl chr16:24,860,667...24,973,341
JBrowse link
G Ldb1 LIM domain binding 1 decreases expression ISO calcium silicate results in decreased expression of LDB1 mRNA CTD PMID:29279043 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013
JBrowse link
G Lmo7 LIM domain 7 decreases expression ISO calcium silicate results in decreased expression of LMO7 mRNA CTD PMID:29279043 NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO calcium silicate results in decreased expression of LTN1 mRNA CTD PMID:29279043 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886
JBrowse link
G Malt1 MALT1 paracaspase increases expression ISO calcium silicate results in increased expression of MALT1 mRNA CTD PMID:29279043 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK1 protein] CTD PMID:21762757 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO calcium silicate results in increased phosphorylation of MAPK3 protein
RTKI cpd inhibits the reaction [calcium silicate results in increased phosphorylation of MAPK3 protein]
CTD PMID:21762757 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Matk megakaryocyte-associated tyrosine kinase increases expression ISO calcium silicate results in increased expression of MATK mRNA CTD PMID:29279043 NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022
JBrowse link
G Mettl8 methyltransferase 8, tRNA N3-cytidine increases expression ISO calcium silicate results in increased expression of METTL8 mRNA CTD PMID:29279043 NCBI chr 3:55,731,453...55,863,652
Ensembl chr 3:55,770,167...55,863,676
JBrowse link
G Mfsd11 major facilitator superfamily domain containing 11 decreases expression ISO calcium silicate results in decreased expression of MFSD11 mRNA CTD PMID:29279043 NCBI chr10:102,055,516...102,075,064
Ensembl chr10:102,056,051...102,075,064
JBrowse link
G Mup18 major urinary protein 18 increases expression ISO calcium silicate results in increased expression of MUP18 mRNA CTD PMID:29279043 NCBI chr 5:74,986,813...74,990,071
Ensembl chr 5:74,842,319...75,061,474
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression ISO calcium silicate results in increased expression of NAA38 mRNA CTD PMID:29279043 NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
JBrowse link
G Nanp N-acetylneuraminic acid phosphatase decreases expression ISO calcium silicate results in decreased expression of NANP mRNA CTD PMID:29279043 NCBI chr 3:139,826,549...139,841,655
Ensembl chr 3:139,826,549...139,841,648
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO calcium silicate results in increased expression of NOP53 mRNA CTD PMID:29279043 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO calcium silicate results in decreased expression of NR1D1 mRNA CTD PMID:29279043 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression ISO calcium silicate results in decreased expression of NR1D2 mRNA CTD PMID:29279043 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO calcium silicate results in increased expression of NTRK3 mRNA CTD PMID:29279043 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Oaf out at first homolog increases expression ISO calcium silicate results in increased expression of OAF mRNA CTD PMID:29279043 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 increases expression ISO calcium silicate results in increased expression of ORMDL2 mRNA CTD PMID:29279043 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 increases expression ISO calcium silicate results in increased expression of OSBPL3 mRNA CTD PMID:29279043 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO calcium silicate results in decreased expression of P4HA2 mRNA CTD PMID:29279043 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314
JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 decreases expression ISO calcium silicate results in decreased expression of PAG1 mRNA CTD PMID:29279043 NCBI chr 2:91,935,378...92,076,937
Ensembl chr 2:92,057,216...92,069,849
JBrowse link
G Per3 period circadian regulator 3 decreases expression ISO calcium silicate results in decreased expression of PER3 mRNA CTD PMID:29279043 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO calcium silicate results in decreased expression of PFKFB3 mRNA CTD PMID:29279043 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression ISO calcium silicate results in increased expression of PHGDH mRNA CTD PMID:29279043 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma increases expression ISO calcium silicate results in increased expression of PIK3CG mRNA CTD PMID:29279043 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Plaa phospholipase A2, activating protein increases expression ISO calcium silicate results in increased expression of PLAA mRNA CTD PMID:29279043 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
JBrowse link
G Pmm2 phosphomannomutase 2 increases expression ISO calcium silicate results in increased expression of PMM2 mRNA CTD PMID:29279043 NCBI chr10:6,961,521...6,982,913
Ensembl chr10:6,961,709...6,983,098
JBrowse link
G Prpf19 pre-mRNA processing factor 19 decreases expression ISO calcium silicate results in decreased expression of PRPF19 mRNA CTD PMID:29279043 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization ISO calcium silicate results in increased localization of RELA protein CTD PMID:21762757 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression ISO calcium silicate results in increased expression of RHOBTB2 mRNA CTD PMID:29279043 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase decreases expression ISO calcium silicate results in decreased expression of RNMT mRNA CTD PMID:29279043 NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775
JBrowse link
G Rps25 ribosomal protein s25 decreases expression ISO calcium silicate results in decreased expression of RPS25 mRNA CTD PMID:29279043 NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271
JBrowse link
G Rwdd3 RWD domain containing 3 increases expression ISO calcium silicate results in increased expression of RWDD3 mRNA CTD PMID:29279043 NCBI chr 2:209,233,622...209,254,842
Ensembl chr 2:209,233,622...209,248,853
JBrowse link
G Scgb3a1 secretoglobin, family 3A, member 1 increases expression ISO calcium silicate results in increased expression of SCGB3A1 mRNA CTD PMID:29279043 NCBI chr10:33,968,059...33,969,366
Ensembl chr10:33,968,059...33,969,476
JBrowse link
G Schip1 schwannomin interacting protein 1 decreases expression ISO calcium silicate results in decreased expression of SCHIP1 mRNA CTD PMID:29279043 NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585
JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression ISO calcium silicate results in decreased expression of SGMS1 mRNA CTD PMID:29279043 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO calcium silicate results in decreased expression of SLC1A5 mRNA CTD PMID:29279043 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc38a10 solute carrier family 38, member 10 decreases expression ISO calcium silicate results in decreased expression of SLC38A10 mRNA CTD PMID:29279043 NCBI chr10:105,386,836...105,436,636
Ensembl chr10:105,386,836...105,436,636
JBrowse link
G Slc6a13 solute carrier family 6 member 13 increases expression ISO calcium silicate results in increased expression of SLC6A13 mRNA CTD PMID:29279043 NCBI chr 4:154,539,246...154,577,784
Ensembl chr 4:154,540,468...154,576,152
JBrowse link
G Snord61 small nucleolar RNA, C/D box 61 decreases expression ISO calcium silicate results in decreased expression of SNORD61 mRNA CTD PMID:29279043 NCBI chr  X:135,313,247...135,313,319
Ensembl chr  X:135,313,247...135,313,319
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity EXP calcium silicate results in decreased activity of SOD1 protein CTD PMID:16601788 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Ssbp3 single stranded DNA binding protein 3 decreases expression ISO calcium silicate results in decreased expression of SSBP3 mRNA CTD PMID:29279043 NCBI chr 5:121,691,370...121,828,035
Ensembl chr 5:121,691,393...121,827,992
JBrowse link
G Taf10 TATA-box binding protein associated factor 10 increases expression ISO calcium silicate results in increased expression of TAF10 mRNA CTD PMID:29279043 NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Zinc binds to calcium silicate] which results in increased expression of TGFB1 mRNA CTD PMID:23483914 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Them7 thioesterase superfamily member 7 increases expression ISO calcium silicate results in increased expression of THEM7 mRNA CTD PMID:29279043 NCBI chr 3:91,666,144...91,834,783
Ensembl chr 3:91,666,152...91,834,783
JBrowse link
G Tmem171 transmembrane protein 171 increases expression ISO calcium silicate results in increased expression of TMEM171 mRNA CTD PMID:29279043 NCBI chr 2:30,035,278...30,045,996
Ensembl chr 2:30,035,278...30,045,049
JBrowse link
G Tmem54 transmembrane protein 54 increases expression ISO calcium silicate results in increased expression of TMEM54 mRNA CTD PMID:29279043 NCBI chr 5:141,449,191...141,455,683
Ensembl chr 5:141,449,191...141,455,682
JBrowse link
G Tmod4 tropomodulin 4 increases expression ISO calcium silicate results in increased expression of TMOD4 mRNA CTD PMID:29279043 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540
JBrowse link
G Tp53 tumor protein p53 increases expression ISO calcium silicate results in increased expression of TRP53 mRNA CTD PMID:29279043 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression ISO calcium silicate results in decreased expression of TUBA1C mRNA CTD PMID:29279043 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion
ISO RTKI cpd inhibits the reaction [calcium silicate results in increased secretion of VEGFA protein] CTD PMID:21762757 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vps35l VPS35 endosomal protein sorting factor like increases expression ISO calcium silicate results in increased expression of VPS35L mRNA CTD PMID:29279043 NCBI chr 1:173,076,219...173,179,663
Ensembl chr 1:173,076,099...173,180,610
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A decreases expression ISO calcium silicate results in decreased expression of ZC3H12A mRNA CTD PMID:29279043 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351
JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 increases expression ISO calcium silicate results in increased expression of ZMYND8 mRNA CTD PMID:29279043 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
JBrowse link
magnesium dihydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased activity of CASP1 protein]; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] promotes the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine results in increased expression of and results in increased secretion of CASP1 protein modified form]; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 PMID:22075093 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Magnesium Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Magnesium Hydroxide inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]] CTD PMID:22750351 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] inhibits the reaction [K-12 lipopolysaccharide results in increased secretion of CXCL10 protein] CTD PMID:17404311 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; CASP1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL1B protein]
[[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein; IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]
CTD PMID:17404311 PMID:18604214 PMID:22075093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein; N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]; TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]] CTD PMID:22075093 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO TLR4 protein affects the reaction [N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine promotes the reaction [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] results in increased secretion of IL2 protein]]; TLR4 protein affects the susceptibility to [[Aluminum Hydroxide co-treated with Magnesium Hydroxide] co-treated with N-t-butyl-n'-tetradecyl-3-tetradecylaminopropionamidine]; TLR4 protein affects the susceptibility to [Aluminum Hydroxide co-treated with Magnesium Hydroxide] CTD PMID:22075093 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
magnesium oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of BAX mRNA] CTD PMID:27920530 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA] CTD PMID:27920530 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA] CTD PMID:27920530 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CASP3 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP3 mRNA] CTD PMID:27920530 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA] CTD PMID:27920530 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Magnesium Oxide analog inhibits the reaction [Diazinon results in increased activity of CASP9 protein]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]; Selenium analog inhibits the reaction [Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]] CTD PMID:27920530 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases expression EXP Magnesium Oxide results in decreased expression of CAT protein CTD PMID:29282847 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CFLAR mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CFLAR mRNA] CTD PMID:27920530 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CYCS mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CYCS mRNA] CTD PMID:27920530 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FADD mRNA]; Magnesium Oxide promotes the reaction [Diazinon results in decreased expression of FADD mRNA] CTD PMID:27920530 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of FAS mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of FAS mRNA] CTD PMID:27920530 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA] CTD PMID:27920530 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased secretion of INS protein alternative form]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased secretion of INS protein]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased secretion of INS protein alternative form]; Magnesium Oxide analog inhibits the reaction [Diazinon results in decreased secretion of INS protein] CTD PMID:27920530 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO Magnesium Oxide analog promotes the reaction [Diazinon results in decreased expression of TNFRSF10A mRNA] CTD PMID:27920530 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TNFRSF1A mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TNFRSF1A mRNA] CTD PMID:27920530 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]; Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TP53 mRNA] CTD PMID:27920530 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf2 Tnf receptor-associated factor 2 multiple interactions ISO Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of TRAF2 mRNA] CTD PMID:27920530 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
sodium hydrogencarbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Sodium Bicarbonate results in increased expression of ABCC2 mRNA CTD PMID:29126803 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression EXP Sodium Bicarbonate results in decreased expression of ABCG2 mRNA CTD PMID:29126803 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Sodium Bicarbonate results in decreased expression of CAR2 mRNA CTD PMID:31569818 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Cat catalase multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in decreased activity of CAT protein CTD PMID:25559736 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of FN1 protein] CTD PMID:10430982 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Sodium Bicarbonate affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] CTD PMID:25559736 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein; [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA] CTD PMID:25559736 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases expression EXP Sodium Bicarbonate results in decreased expression of SLC15A1 mRNA CTD PMID:29126803 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545
JBrowse link
G Slc22a19 solute carrier family 22, member 19 increases expression EXP Sodium Bicarbonate results in increased expression of SLC22A24 mRNA CTD PMID:29126803 NCBI chr 1:204,910,450...204,965,538
Ensembl chr 1:204,910,455...204,965,538
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases expression EXP Sodium Bicarbonate results in decreased expression of SLC22A6 mRNA CTD PMID:29126803 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions EXP SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of Cadmium Chloride]; SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of manganese chloride] CTD PMID:21509381 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) decreases expression EXP Sodium Bicarbonate results in decreased expression of SLC4A1 mRNA CTD PMID:31569818 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases transport
decreases expression
ISO
EXP
SLC4A4 protein results in increased transport of Sodium Bicarbonate
Sodium Bicarbonate results in decreased expression of SLC4A4 mRNA
CTD PMID:18614622 PMID:31569818 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of TGFB1 mRNA] CTD PMID:10430982 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA] CTD PMID:25559736 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein; [Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA] CTD PMID:25559736 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vim vimentin multiple interactions EXP Sodium Bicarbonate inhibits the reaction [Doxorubicin results in increased expression of VIM protein] CTD PMID:10430982 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19810
      biological role 19808
        pharmacological role 19043
          antacid 175
            aluminium hydroxide + 48
            calcium carbonate + 7
            calcium silicate 100
            magnesium carbonate 0
            magnesium dihydroxide 10
            magnesium oxide + 17
            sodium hydrogencarbonate 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19810
      application 19679
        pharmaceutical 19495
          drug 19520
            antacid 175
              aluminium hydroxide + 48
              calcium carbonate + 7
              calcium silicate 100
              magnesium carbonate 0
              magnesium dihydroxide 10
              magnesium oxide + 17
              sodium hydrogencarbonate 18
paths to the root