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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:amidoxime
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Accession:CHEBI:65234 term browser browse the term
Definition:Amidines of general formula RC(=NOH)NR(1)R(2), in which the imino nitrogen is substituted by a hydroxy group.
Synonyms:related_synonym: amidoximes

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benzamidoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5b cytochrome b5 type B multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of benzamidoxime; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of benzamidoxime CTD PMID:22924387 NCBI chr19:39,357,814...39,391,680
Ensembl chr19:39,357,791...39,393,189 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of benzamidoxime; [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of benzamidoxime CTD PMID:22924387 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC1 protein] results in increased reduction of benzamidoxime CTD PMID:22924387 NCBI chr13:102,693,679...102,724,120
Ensembl chr13:102,698,546...102,721,218 		JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 multiple interactions ISO [CYB5B protein co-treated with CYB5R3 protein co-treated with MTARC2 protein] results in increased reduction of benzamidoxime CTD PMID:22924387 NCBI chr13:102,724,266...102,755,511
Ensembl chr13:102,724,348...102,756,174 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO UGT1A1 protein results in increased glucuronidation of and results in decreased activity of benzamidoxime CTD PMID:15788365 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO UGT1A3 protein results in increased glucuronidation of and results in decreased activity of benzamidoxime CTD PMID:15788365 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822 		JBrowse link
ximelagatran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II decreases cleavage
multiple interactions		 ISO ximelagatran results in decreased cleavage of F2 protein
ximelagatran binds to and results in decreased activity of F2 protein		 CTD PMID:15155122 PMID:16084352 PMID:16194202 PMID:17314111 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19841
      atom 19839
        nonmetal atom 19720
          nitrogen atom 18613
            nitrogen molecular entity 18613
              amidine 812
                amidoxime 7
                  benzamidoxime 6
                  ximelagatran 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      pnictogen 18718
                        nitrogen atom 18613
                          nitrogen molecular entity 18613
                            amidine 812
                              amidoxime 7
                                benzamidoxime 6
                                ximelagatran 1
paths to the root