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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:first generation antipsychotic
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Accession:CHEBI:65190 term browser browse the term
Definition:Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
Synonyms:related_synonym: first generation antipsychotic agent;   first generation antipsychotic agents;   first generation antipsychotic drug;   first generation antipsychotic drugs;   first generation antipsychotics;   typical antipsychotic;   typical antipsychotic agent;   typical antipsychotic agents;   typical antipsychotic drug;   typical antipsychotic drugs;   typical antipsychotics
 xref: Wikipedia:Typical_antipsychotic


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(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
acepromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO Acepromazine results in increased activity of ACHE protein CTD PMID:29614332 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
acetophenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO acetophenazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
chlorpromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
ISO
EXP
[Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB11 mRNA
Chlorpromazine results in decreased expression of ABCB11 mRNA
CTD PMID:27344345, PMID:27765674, PMID:28391356 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases activity
ISO Chlorpromazine analog results in increased expression of ABCB1 mRNA
Chlorpromazine results in decreased activity of ABCB1 protein
CTD PMID:15924885, PMID:16810505 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B affects activity EXP Chlorpromazine affects the activity of ABCB1B protein CTD PMID:12626638 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression EXP Chlorpromazine results in decreased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression EXP Chlorpromazine results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Chlorpromazine results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
ISO
EXP
Chlorpromazine analog results in increased expression of ABCC3 mRNA
Chlorpromazine results in decreased expression of ABCC3 mRNA
CTD PMID:15924885, PMID:25596134 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Chlorpromazine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCG8 mRNA CTD PMID:27344345 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases phosphorylation EXP Chlorpromazine results in decreased phosphorylation of ACACA protein CTD PMID:17512020 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ache acetylcholinesterase decreases activity
increases activity
multiple interactions
ISO Chlorpromazine results in decreased activity of ACHE protein
Chlorpromazine results in increased activity of ACHE protein
Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]
CTD PMID:4859365, PMID:29614332 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA] CTD PMID:21869564 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Adra1a adrenoceptor alpha 1A decreases activity EXP Chlorpromazine results in decreased activity of ADRA1A protein CTD PMID:23611293 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases activity EXP Chlorpromazine results in decreased activity of ADRA1B protein CTD PMID:23611293 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Afp alpha-fetoprotein decreases expression ISO Chlorpromazine analog results in decreased expression of AFP mRNA CTD PMID:15924885 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agrn agrin decreases expression EXP Chlorpromazine results in decreased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahr aryl hydrocarbon receptor affects activity EXP Chlorpromazine affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak3 adenylate kinase 3 decreases expression EXP Chlorpromazine results in decreased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP Chlorpromazine results in decreased phosphorylation of AKT1 protein CTD PMID:17512020 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ALDH1A1 mRNA CTD PMID:27344345 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Chlorpromazine results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions ISO Chlorpromazine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Chlorpromazine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Chlorpromazine results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr12:22,665,128...22,676,079
Ensembl chr12:22,665,112...22,676,075
JBrowse link
G Apoc4 apolipoprotein C4 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOC4 mRNA CTD PMID:27344345 NCBI chr 1:80,595,339...80,599,525
Ensembl chr 1:80,595,326...80,599,572
JBrowse link
G Apof apolipoprotein F multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOF mRNA CTD PMID:27344345 NCBI chr 7:2,689,501...2,690,938
Ensembl chr 7:2,689,501...2,690,936
JBrowse link
G Areg amphiregulin decreases expression ISO Chlorpromazine results in decreased expression of AREG mRNA CTD PMID:15924885, PMID:30703373 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 increases expression EXP Chlorpromazine results in increased expression of ARFGEF2 mRNA CTD PMID:25596134 NCBI chr 3:163,570,435...163,656,612
Ensembl chr 3:163,570,532...163,656,626
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 decreases expression EXP Chlorpromazine results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:79,725,629...79,817,065
Ensembl chr16:79,725,643...79,793,619
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Chlorpromazine results in increased expression of ASAH1 mRNA CTD PMID:17175557 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Chlorpromazine results in increased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf4 activating transcription factor 4 affects activity
multiple interactions
EXP
ISO
Chlorpromazine affects the activity of ATF4 protein
[Chlorpromazine co-treated with Cholic Acids] affects the expression of ATF4 mRNA
CTD PMID:25596134, PMID:27344345 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression EXP Chlorpromazine results in decreased expression of ATP6V1B2 protein CTD PMID:19441803 NCBI chr16:22,326,537...22,350,143
Ensembl chr16:22,326,529...22,350,155
JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions
ISO
EXP
Chlorpromazine results in increased expression of AVP protein
Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein]
CTD PMID:3567260, PMID:3976404 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bag4 BAG cochaperone 4 decreases expression ISO Chlorpromazine analog results in decreased expression of BAG4 mRNA CTD PMID:15924885 NCBI chr16:71,057,709...71,075,874
Ensembl chr16:71,058,022...71,075,320
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Chlorpromazine results in increased expression of BCL2L1 mRNA CTD PMID:21683644 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor affects response to substance
affects expression
ISO
EXP
BDNF affects the susceptibility to Chlorpromazine
Chlorpromazine affects the expression of BDNF mRNA
CTD PMID:18408624, PMID:31324950 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Chlorpromazine analog results in increased expression of BHLHE40 mRNA CTD PMID:15924885 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Chlorpromazine results in decreased expression of BIRC2 mRNA CTD PMID:30703373 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Chlorpromazine analog results in decreased expression of BIRC5 mRNA; Chlorpromazine results in decreased expression of BIRC5 mRNA CTD PMID:15924885, PMID:30703373 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP Chlorpromazine results in increased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Chlorpromazine analog results in increased expression of BTG2 mRNA CTD PMID:15924885 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO Chlorpromazine analog results in increased expression of BTG3 mRNA CTD PMID:15924885 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G C3 complement C3 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of C3 mRNA CTD PMID:27344345 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C6 complement C6 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of C6 mRNA CTD PMID:27344345 NCBI chr 2:54,460,333...54,533,801
Ensembl chr 2:54,466,280...54,533,797
JBrowse link
G Calcr calcitonin receptor multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Calr calreticulin decreases expression EXP Chlorpromazine results in decreased expression of CALR mRNA CTD PMID:18246545 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA] CTD PMID:21869564 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
EXP
ISO
carvedilol inhibits the reaction [Chlorpromazine results in decreased expression of CAT protein]; zolpidem inhibits the reaction [Chlorpromazine results in decreased activity of CAT] CTD PMID:12010767, PMID:17513028, PMID:25449126 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Chlorpromazine results in decreased expression of CCN2 mRNA; Chlorpromazine results in decreased expression of CCN2 protein CTD PMID:30703373 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccn3 cellular communication network factor 3 affects expression EXP Chlorpromazine affects the expression of CCN3 mRNA CTD PMID:31324950 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Chlorpromazine analog results in decreased expression of CCNB2 mRNA; Chlorpromazine results in decreased expression of CCNB2 mRNA CTD PMID:15924885 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Chlorpromazine results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Chlorpromazine analog results in decreased expression of CCND3 mRNA CTD PMID:15924885 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccnf cyclin F decreases expression ISO Chlorpromazine analog results in decreased expression of CCNF mRNA CTD PMID:15924885 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Cd274 CD274 molecule multiple interactions ISO Chlorpromazine inhibits the reaction [platycodin D results in decreased expression of and results in increased secretion of CD274 protein] CTD PMID:31150782 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
decreases expression
ISO Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]
Chlorpromazine results in decreased expression of CD44 protein
CTD PMID:9929743, PMID:30703373 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd86 CD86 molecule increases expression ISO Chlorpromazine results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO Chlorpromazine analog results in decreased expression of CDK5 mRNA CTD PMID:15924885 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression ISO Chlorpromazine analog results in increased expression of CDK7 mRNA CTD PMID:15924885 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
EXP [EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA] CTD PMID:20368687 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Chlorpromazine analog results in decreased expression of CDKN2C mRNA CTD PMID:15924885 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CES2 mRNA CTD PMID:27344345 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cfh complement factor H multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CFH mRNA CTD PMID:27344345 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 decreases expression EXP Chlorpromazine results in decreased expression of CGREF1 mRNA CTD PMID:17202759 NCBI chr 6:26,797,126...26,809,132
Ensembl chr 6:26,797,126...26,809,129
JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 decreases expression ISO Chlorpromazine analog results in decreased expression of CHTF18 mRNA CTD PMID:15924885 NCBI chr10:15,090,762...15,098,825
Ensembl chr10:15,090,316...15,098,791
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP Chlorpromazine results in decreased expression of CITED2 mRNA CTD PMID:18246545 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Chlorpromazine analog results in decreased expression of CKS2 mRNA CTD PMID:15924885 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO Chlorpromazine results in increased expression of CLCF1 mRNA CTD PMID:21683644 NCBI chr 1:219,468,866...219,472,445
Ensembl chr 1:219,468,675...219,472,654
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of COL18A1 mRNA CTD PMID:27344345 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression EXP Chlorpromazine results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Cort cortistatin affects expression EXP Chlorpromazine affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 5:165,942,780...165,944,221 JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression
increases expression
EXP Chlorpromazine affects the expression of COX8A mRNA
Chlorpromazine results in increased expression of COX8A mRNA
CTD PMID:18246545 NCBI chr 1:222,466,575...222,468,896
Ensembl chr 1:222,466,575...222,468,896
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Chlorpromazine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP Chlorpromazine results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsk cathepsin K multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:21869564 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases response to substance
increases expression
ISO
EXP
[Filipin co-treated with Chlorpromazine co-treated with Wortmannin] inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CYP1A1 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in increased expression of CYP1A1 mRNA
CTD PMID:17202759, PMID:18246545, PMID:18493746, PMID:25596134, PMID:26477383, PMID:29724254 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases response to substance
increases expression
increases oxidation
affects expression
decreases methylation
ISO
EXP
[Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; CYP1A2 protein results in increased metabolism of and results in increased activity of Chlorpromazine
CYP1A2 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in increased expression of CYP1A2 mRNA
CYP1A2 protein results in increased oxidation of Chlorpromazine
Chlorpromazine affects the expression of CYP1A2 mRNA
CYP1A2 protein results in decreased methylation of Chlorpromazine
CTD PMID:18246545, PMID:18493746, PMID:19482014, PMID:20615392, PMID:23397584, PMID:25596134, PMID:26477383, PMID:27344345 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance
multiple interactions
ISO CYP1B1 protein results in decreased susceptibility to Chlorpromazine
[Filipin co-treated with Chlorpromazine co-treated with Wortmannin] inhibits the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]
CTD PMID:26477383, PMID:29724254 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP2B10 mRNA] CTD PMID:12049174 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases response to substance
ISO [Chlorpromazine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Chlorpromazine inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]
CYP2B6 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:10037683, PMID:17041008, PMID:26477383 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Chlorpromazine results in decreased expression of CYP2C mRNA; Chlorpromazine results in decreased expression of CYP2C11 mRNA CTD PMID:18246545 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases response to substance ISO CYP2C18 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions
decreases response to substance
decreases activity
affects methylation
ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine
CYP2C19 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of CYP2C19 protein
CYP2C19 protein affects the methylation of Chlorpromazine
CTD PMID:15135088, PMID:20615392, PMID:23397584, PMID:26477383 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases response to substance ISO CYP2C8 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases response to substance
ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine; CYP2D6 protein results in increased metabolism of and results in increased activity of Chlorpromazine
CYP2D6 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:19482014, PMID:23397584, PMID:26477383 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
decreases response to substance
ISO Chlorpromazine results in decreased activity of CYP2E1 protein
CYP2E1 protein results in decreased susceptibility to Chlorpromazine
CTD PMID:15135088, PMID:26477383 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases response to substance ISO CYP3A5 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP8B1 mRNA CTD PMID:27344345 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dao D-amino-acid oxidase decreases activity ISO Chlorpromazine results in decreased activity of DAO protein CTD PMID:18615285 NCBI chr12:48,353,691...48,373,647
Ensembl chr12:48,354,196...48,365,784
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA] CTD PMID:21869564 NCBI chr 7:78,642,016...78,651,763
Ensembl chr 7:78,649,875...78,650,906
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP Chlorpromazine results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Chlorpromazine results in increased expression of DEPP1 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Drd1 dopamine receptor D1 decreases activity ISO Chlorpromazine results in decreased activity of DRD1 protein CTD PMID:23611293 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 decreases response to substance
decreases activity
ISO DRD2 polymorphism results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of DRD2 protein
CTD PMID:15694263, PMID:23611293 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression
affects expression
ISO Chlorpromazine analog results in increased expression of DUSP1 mRNA
Chlorpromazine affects the expression of DUSP1 mRNA
CTD PMID:15924885, PMID:20843724 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp9 dual specificity phosphatase 9 decreases expression ISO Chlorpromazine analog results in decreased expression of DUSP9 mRNA CTD PMID:15924885 NCBI chr  X:157,168,143...157,172,068
Ensembl chr  X:157,168,144...157,172,068
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Chlorpromazine analog results in decreased expression of E2F1 mRNA CTD PMID:15924885 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
EXP Chlorpromazine results in increased expression of EGR1
[EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; MAPK1 affects the reaction [Chlorpromazine results in increased expression of EGR1]; MAPK3 affects the reaction [Chlorpromazine results in increased expression of EGR1]
CTD PMID:20368687 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression EXP Chlorpromazine results in increased expression of EIF1 mRNA CTD PMID:25596134 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eno2 enolase 2 increases expression EXP Chlorpromazine results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Chlorpromazine results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G F2 coagulation factor II decreases expression ISO Chlorpromazine analog results in decreased expression of F2 mRNA CTD PMID:15924885 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Chlorpromazine results in increased expression of FABP1 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Chlorpromazine analog results in increased expression of FAS mRNA CTD PMID:15924885 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbp1 fructose-bisphosphatase 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FBP1 mRNA CTD PMID:27344345 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fbxo22 F-box protein 22 decreases expression EXP Chlorpromazine results in decreased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
JBrowse link
G Fech ferrochelatase decreases expression EXP Chlorpromazine results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:59,941,992...59,975,192
Ensembl chr18:59,941,992...59,975,192
JBrowse link
G Fetub fetuin B multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FETUB mRNA CTD PMID:27344345 NCBI chr11:81,648,890...81,660,472
Ensembl chr11:81,648,885...81,660,395
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FGA mRNA CTD PMID:27344345 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FGF2 mRNA CTD PMID:27344345 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Chlorpromazine analog results in decreased expression of FGFR1 mRNA CTD PMID:15924885 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression EXP Chlorpromazine results in decreased expression of FGR mRNA CTD PMID:25596134 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO Chlorpromazine inhibits the reaction [Lipopolysaccharides results in decreased expression of FKBP5 protein] CTD PMID:21034739 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO Chlorpromazine affects the expression of FOS mRNA CTD PMID:20843724 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit affects expression ISO Chlorpromazine affects the expression of FOSB mRNA CTD PMID:20843724 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
affects expression
ISO Chlorpromazine analog results in increased expression of FOSL1 mRNA
Chlorpromazine affects the expression of FOSL1 mRNA
CTD PMID:15924885, PMID:20843724 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit affects expression ISO Chlorpromazine affects the expression of FOSL2 mRNA CTD PMID:20843724 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FTH1 mRNA CTD PMID:27344345 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO Chlorpromazine analog results in decreased expression of G6PD mRNA CTD PMID:15924885 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases methylation
multiple interactions
ISO Chlorpromazine results in decreased methylation of GAD1 promoter
Valproic Acid promotes the reaction [Chlorpromazine results in decreased methylation of GAD1 promoter]
CTD PMID:19110320 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of GCGR mRNA CTD PMID:27344345 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP Chlorpromazine results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP Chlorpromazine results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Chlorpromazine results in increased expression of GDPD3 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Gfap glial fibrillary acidic protein affects expression EXP Chlorpromazine affects the expression of GFAP mRNA CTD PMID:31324950 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Chlorpromazine results in increased expression of GPNMB mRNA CTD PMID:25596134 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP Chlorpromazine results in decreased activity of GSR protein CTD PMID:6693892 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of GSTA1 mRNA CTD PMID:27344345 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects activity EXP Chlorpromazine affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Chlorpromazine results in increased expression of HMGCR mRNA CTD PMID:17052361 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Chlorpromazine results in increased expression of HMGCS1 mRNA CTD PMID:17052361 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression
ISO
EXP
Chlorpromazine results in increased expression of HMOX1 mRNA
Chlorpromazine affects the expression of HMOX1 mRNA
CTD PMID:15924885, PMID:25596134, PMID:31324950 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpn hepsin increases expression ISO Chlorpromazine results in increased expression of HPN mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
G Ibsp integrin-binding sialoprotein decreases expression
multiple interactions
EXP Chlorpromazine results in decreased expression of IBSP mRNA
herbimycin inhibits the reaction [Chlorpromazine results in decreased expression of IBSP mRNA]; U 0126 inhibits the reaction [Chlorpromazine results in decreased expression of IBSP mRNA]
CTD PMID:16294319 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA CTD PMID:29594315 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifnlr1 interferon, lambda receptor 1 increases expression ISO Chlorpromazine results in increased expression of IFNLR1 mRNA CTD PMID:21683644 NCBI chr 5:154,037,243...154,058,862
Ensembl chr 5:154,037,202...154,058,880
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Chlorpromazine results in increased expression of IGFBP1 mRNA CTD PMID:15924885 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression ISO Chlorpromazine analog results in increased expression of IKBKG mRNA CTD PMID:15924885 NCBI chr  X:156,254,187...156,280,046
Ensembl chr  X:156,257,173...156,270,748
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Chlorpromazine results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:11014349, PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Chlorpromazine results in increased expression of INHBE mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Chlorpromazine results in decreased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP Chlorpromazine results in decreased expression of and results in decreased phosphorylation of IRS2 protein; Chlorpromazine results in decreased expression of and results in increased degradation of IRS2 protein CTD PMID:17512020, PMID:18308779 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Chlorpromazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Chlorpromazine results in decreased activity of KCNH2 protein
CTD PMID:15071359, PMID:21158687, PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases activity EXP Chlorpromazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions
decreases expression
ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KLF4 mRNA
Chlorpromazine results in decreased expression of KLF4 mRNA
CTD PMID:27344345, PMID:30703373 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klkb1 kallikrein B1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KLKB1 mRNA CTD PMID:27344345 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Kng2 kininogen 2 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KNG1 mRNA CTD PMID:27344345 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Lats1 large tumor suppressor kinase 1 increases phosphorylation ISO Chlorpromazine results in increased phosphorylation of LATS1 protein CTD PMID:30703373 NCBI chr 1:1,784,078...1,817,310
Ensembl chr 1:1,784,078...1,817,310
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Chlorpromazine results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lep leptin increases expression EXP Chlorpromazine results in increased expression of LEP protein CTD PMID:17512020 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lss lanosterol synthase increases expression ISO Chlorpromazine results in increased expression of LSS mRNA CTD PMID:15342952, PMID:17175557 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Chlorpromazine results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]
MAPK1 affects the reaction [Chlorpromazine results in increased expression of EGR1]
CTD PMID:11014349, PMID:20368687 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression ISO Chlorpromazine analog results in decreased expression of MAPK14 mRNA CTD PMID:15924885 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
multiple interactions
ISO
EXP
Chlorpromazine analog results in decreased expression of MAPK3 mRNA
MAPK3 affects the reaction [Chlorpromazine results in increased expression of EGR1]
Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:11014349, PMID:15924885, PMID:20368687 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein; Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]] CTD PMID:23238562 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression EXP Chlorpromazine results in increased expression of MAPKAPK2 mRNA CTD PMID:19441803 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Chlorpromazine analog results in decreased expression of MCM3 mRNA CTD PMID:15924885 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Chlorpromazine analog results in decreased expression of MCM5 mRNA CTD PMID:15924885 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Chlorpromazine results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Chlorpromazine results in increased expression of MITF protein CTD PMID:25449126 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Chlorpromazine analog results in decreased expression of MKI67 mRNA CTD PMID:15924885 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Chlorpromazine inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; Chlorpromazine inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein] CTD PMID:25200491 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Msc musculin decreases expression EXP Chlorpromazine results in decreased expression of MSC mRNA CTD PMID:25596134 NCBI chr 5:3,954,902...3,956,974
Ensembl chr 5:3,955,227...3,956,572
JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO Chlorpromazine results in decreased expression of MSH2 mRNA CTD PMID:15924885 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Mst1 macrophage stimulating 1 increases phosphorylation ISO Chlorpromazine results in increased phosphorylation of MST1 protein CTD PMID:30703373 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Chlorpromazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO Chlorpromazine analog results in decreased expression of MYBL2 mRNA CTD PMID:15924885 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Chlorpromazine results in decreased expression of MYC mRNA CTD PMID:30703373 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Chlorpromazine results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Chlorpromazine results in decreased expression of NANOG mRNA CTD PMID:30703373 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression EXP Chlorpromazine results in decreased expression of NDUFS3 protein CTD PMID:19441803 NCBI chr 3:79,721,686...79,728,863
Ensembl chr 3:79,721,694...79,728,879
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 multiple interactions ISO Chlorpromazine inhibits the reaction [Cadmium Chloride results in decreased expression of and affects the localization of NECTIN2 protein] CTD PMID:25046863 NCBI chr 1:80,631,449...80,666,617
Ensembl chr 1:80,631,450...80,666,585
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression EXP Chlorpromazine results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nefh neurofilament heavy affects expression EXP Chlorpromazine affects the expression of NEFH mRNA CTD PMID:31324950 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:21869564 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression
affects activity
EXP Chlorpromazine results in decreased expression of NFE2L2 mRNA
Chlorpromazine affects the activity of NFE2L2 protein
CTD PMID:25596134 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ninj1 ninjurin 1 increases expression EXP Chlorpromazine results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Chlorpromazine results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP Chlorpromazine results in decreased expression of NR1H4 mRNA CTD PMID:27765674, PMID:28391356 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions
ISO Chlorpromazine analog results in increased expression of NR1I2 mRNA
[Chlorpromazine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
CTD PMID:15924885, PMID:17041008 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity
increases expression
multiple interactions
ISO Chlorpromazine results in increased activity of NR1I3 protein
Chlorpromazine results in increased expression of NR1I3 mRNA
[Chlorpromazine co-treated with Cholic Acids] affects the expression of NR1I3 mRNA; [Chlorpromazine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Chlorpromazine inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]
NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP3A11 mRNA]
CTD PMID:10037683, PMID:12049174, PMID:12948398, PMID:17041008, PMID:22310298, PMID:27344345 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Chlorpromazine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein] CTD PMID:16581232 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Chlorpromazine results in increased expression of NUPR1 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO Chlorpromazine analog results in decreased expression of ORC1 mRNA CTD PMID:15924885 NCBI chr 5:128,186,651...128,212,901
Ensembl chr 5:128,190,708...128,210,445
JBrowse link
G Orm1 orosomucoid 1 affects binding
multiple interactions
ISO Chlorpromazine binds to ORM1 protein alternative form
Chlorpromazine inhibits the reaction [Warfarin binds to ORM1 protein alternative form]
CTD PMID:8946472 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 increases expression ISO Chlorpromazine analog results in increased expression of PDIA2 mRNA CTD PMID:15924885
G Pdia5 protein disulfide isomerase family A, member 5 decreases expression EXP Chlorpromazine results in decreased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:68,493,035...68,578,999
Ensembl chr11:68,493,035...68,578,995
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression EXP Chlorpromazine results in increased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Chlorpromazine results in increased expression of PDK4 mRNA CTD PMID:25596134 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase increases expression ISO Chlorpromazine results in increased expression of PHYH mRNA CTD PMID:15342952 NCBI chr17:77,287,580...77,304,482
Ensembl chr17:77,287,188...77,304,530
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 increases expression ISO Chlorpromazine results in increased expression of PIAS1 mRNA CTD PMID:21683644 NCBI chr 8:67,771,720...67,869,015
Ensembl chr 8:67,771,720...67,869,019
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO Chlorpromazine analog results in increased expression of PIM1 mRNA CTD PMID:15924885 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Pir pirin decreases expression EXP Chlorpromazine results in decreased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Plin2 perilipin 2 increases expression EXP Chlorpromazine results in increased expression of PLIN2 mRNA CTD PMID:25596134 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression EXP Chlorpromazine results in decreased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:171,295,630...171,342,662
Ensembl chr 3:171,294,856...171,342,646
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO Chlorpromazine analog results in decreased expression of POLA1 mRNA CTD PMID:15924885 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO Chlorpromazine analog results in increased expression of POLD4 mRNA CTD PMID:15924885 NCBI chr 1:219,480,841...219,483,244
Ensembl chr 1:219,481,575...219,483,241
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Chlorpromazine results in decreased expression of POU5F1 mRNA CTD PMID:30703373 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity EXP Chlorpromazine affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Chlorpromazine results in increased expression of PPP1R15A mRNA CTD PMID:25596134 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation EXP Chlorpromazine results in decreased phosphorylation of PRKAA1 protein CTD PMID:17512020 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prl prolactin increases expression ISO Chlorpromazine results in increased expression of PRL protein CTD PMID:718334, PMID:996201 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression EXP Chlorpromazine results in decreased expression of RARA mRNA CTD PMID:18246545 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression EXP Chlorpromazine results in decreased expression of RND1 mRNA CTD PMID:25596134 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression EXP Chlorpromazine results in decreased expression of RND3 mRNA CTD PMID:25596134 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Rnf121 ring finger protein 121 decreases expression EXP Chlorpromazine results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 1:167,095,916...167,165,257
Ensembl chr 1:167,095,962...167,165,265
JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression EXP Chlorpromazine results in increased expression of RUNX1 mRNA CTD PMID:25596134 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance ISO RXRG protein affects the susceptibility to Chlorpromazine CTD PMID:10336693 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP Chlorpromazine results in increased expression of SAT1 mRNA CTD PMID:25596134 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Chlorpromazine results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Serpina3m serpin family A member 3M increases expression ISO Chlorpromazine results in increased expression of SERPINA3 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Sesn1 sestrin 1 decreases expression EXP Chlorpromazine results in decreased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression EXP Chlorpromazine results in decreased expression of SIK1 mRNA CTD PMID:25596134 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Chlorpromazine results in decreased expression of SLC10A1 mRNA CTD PMID:27765674, PMID:28391356 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc12a8 solute carrier family 12, member 8 increases expression EXP Chlorpromazine results in increased expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:70,344,771...70,499,202
Ensembl chr11:70,344,797...70,499,200
JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity
EXP Chlorpromazine inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Chlorpromazine results in decreased activity of SLC19A1 protein
CTD PMID:17482559 NCBI chr20:12,334,675...12,354,517
Ensembl chr20:12,334,676...12,352,377
JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression EXP Chlorpromazine results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:78,710,686...78,724,789
Ensembl chr 1:78,710,539...78,724,794
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Chlorpromazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SLC22A7 mRNA CTD PMID:27344345 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Chlorpromazine results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO Chlorpromazine inhibits the reaction [Copper affects the localization of SLC31A1 protein] CTD PMID:12501239 NCBI chr 5:78,222,504...78,249,358
Ensembl chr 5:78,222,504...78,249,358
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression EXP Chlorpromazine results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc51b solute carrier family 51 subunit beta multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SLC51B mRNA CTD PMID:27344345 NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP Chlorpromazine results in increased expression of SLC6A6 mRNA CTD PMID:25596134 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression EXP Chlorpromazine results in decreased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Chlorpromazine inhibits the reaction [Copper inhibits the reaction [Trientine results in decreased activity of SOD1 protein]] CTD PMID:22362149 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO Chlorpromazine results in decreased expression of SOX2 mRNA CTD PMID:30703373 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SPP1 mRNA CTD PMID:27344345 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP Chlorpromazine results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 5:166,913,734...166,978,534
Ensembl chr 5:166,913,735...166,926,636
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP Chlorpromazine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein] CTD PMID:29702141 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Chlorpromazine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression EXP Chlorpromazine results in increased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 3:21,817,680...21,956,988
Ensembl chr 3:21,828,298...21,904,270
JBrowse link
G Sts steroid sulfatase multiple interactions ISO Chlorpromazine inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Tagln transgelin decreases expression ISO Chlorpromazine results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tf transferrin affects localization ISO Chlorpromazine affects the localization of TF protein CTD PMID:12501239 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO Chlorpromazine analog results in decreased expression of TFDP1 mRNA CTD PMID:15924885 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression EXP Chlorpromazine results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tirap TIR domain containing adaptor protein multiple interactions ISO TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]]; TIRAP protein results in increased susceptibility to [Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4]; TIRAP protein results in increased susceptibility to [Chlorpromazine co-treated with lipoteichoic acid] CTD PMID:23238562 NCBI chr 8:36,382,029...36,399,625
Ensembl chr 8:36,385,353...36,388,224
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases response to substance
multiple interactions
ISO Chlorpromazine analog results in decreased expression of TNF protein; Chlorpromazine results in decreased expression of TNF mRNA
TNF protein results in increased susceptibility to Chlorpromazine
[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein; [Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein; Chlorpromazine inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; Chlorpromazine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [TNF protein results in increased susceptibility to Chlorpromazine]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein]
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine; Chlorpromazine results in decreased expression of and results in decreased activity of TNF protein
CTD PMID:8550079, PMID:15052360, PMID:19362101, PMID:20371967, PMID:22414385, PMID:23238562 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 increases expression EXP Chlorpromazine results in increased expression of TNFAIP8 mRNA CTD PMID:25596134 NCBI chr18:44,664,310...44,779,914
Ensembl chr18:44,716,226...44,779,914
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO Chlorpromazine analog results in increased expression of TNFRSF14 mRNA CTD PMID:15924885 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases activity
multiple interactions
ISO Chlorpromazine results in decreased activity of TNFSF11; Chlorpromazine results in decreased activity of TNFSF11 protein
Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]
CTD PMID:21869564 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tp53 tumor protein p53 affects activity EXP Chlorpromazine affects the activity of TP53 protein CTD PMID:25596134 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression EXP Chlorpromazine results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:40,695,520...40,709,438
Ensembl chr12:40,695,520...40,709,462
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO Chlorpromazine results in decreased expression of TUBA1A mRNA CTD PMID:27015953 NCBI chr 7:140,637,287...140,640,953
Ensembl chr 7:140,637,287...140,640,953
JBrowse link
G Txn1 thioredoxin 1 decreases expression EXP Chlorpromazine results in decreased expression of TXN1 mRNA CTD PMID:25596134 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of TXNRD1 mRNA CTD PMID:27344345 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyr tyrosinase increases expression ISO Chlorpromazine results in increased expression of TYR protein CTD PMID:25449126 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Ung uracil-DNA glycosylase decreases expression ISO Chlorpromazine analog results in decreased expression of UNG mRNA CTD PMID:15924885 NCBI chr12:48,246,593...48,255,547
Ensembl chr12:48,246,569...48,254,822
JBrowse link
G Unkl unk like zinc finger decreases expression EXP Chlorpromazine results in decreased expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,547,126...14,593,090
Ensembl chr10:14,547,172...14,590,762
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Chlorpromazine analog results in increased expression of VEGFA mRNA CTD PMID:15924885 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfb vascular endothelial growth factor B increases expression EXP Chlorpromazine results in increased expression of VEGFB mRNA CTD PMID:25596134 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression EXP Chlorpromazine results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Chlorpromazine results in increased expression of WIPI1 mRNA CTD PMID:15342952, PMID:17175557 NCBI chr10:97,859,730...97,896,949
Ensembl chr10:97,859,727...97,896,525
JBrowse link
G Xbp1 X-box binding protein 1 affects activity
decreases expression
EXP Chlorpromazine affects the activity of XBP1 protein
Chlorpromazine results in decreased expression of XBP1 mRNA
CTD PMID:25596134 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression EXP Chlorpromazine results in decreased expression of XPC mRNA CTD PMID:25596134 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases expression ISO Chlorpromazine results in decreased expression of XRCC4 mRNA CTD PMID:15924885 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions ISO Chlorpromazine results in decreased expression of and results in increased phosphorylation of and affects the localization of YAP1 protein CTD PMID:30703373 NCBI chr 8:6,133,014...6,204,240
Ensembl chr 8:6,135,493...6,203,579
JBrowse link
chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
droperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions
ISO Droperidol results in decreased activity of KCNH2 protein
Droperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
CTD PMID:16757186, PMID:21158687, PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Droperidol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
flupenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
ISO Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
Flupenthixol analog results in decreased activity of ABCB1 protein; Flupenthixol analog results in decreased activity of ABCB1 protein mutant form
CTD PMID:7905786, PMID:12711602 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Flupenthixol binds to DRD1 protein CTD PMID:1352677 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Flupenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Flupenthixol results in decreased expression of PTGS1 protein CTD PMID:8897462 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Flupenthixol results in decreased expression of PTGS2 protein CTD PMID:8897462 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
fluphenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
EXP [Fluphenazine co-treated with diphenyldiselenide] results in decreased activity of ALAD protein
Fluphenazine results in decreased activity of ALAD protein
CTD PMID:19486337 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Ar androgen receptor multiple interactions ISO Fluphenazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP diphenyldiselenide inhibits the reaction [Fluphenazine results in increased activity of CAT protein] CTD PMID:19486337 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Fluphenazine results in decreased activity of CYP2C19 protein CTD PMID:15135088 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Fluphenazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Drd2 dopamine receptor D2 affects binding ISO Fluphenazine binds to DRD2 protein CTD PMID:17606915 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding ISO Fluphenazine binds to HTR2A protein CTD PMID:17606915 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding ISO Fluphenazine binds to HTR2C protein CTD PMID:17606915 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Prl prolactin increases secretion ISO Fluphenazine results in increased secretion of PRL protein CTD PMID:9989566 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Fluphenazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression ISO Fluphenazine results in decreased expression of TAC1 mRNA CTD PMID:15845098 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tfeb transcription factor EB affects localization ISO Fluphenazine affects the localization of TFEB protein CTD PMID:28366621 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
decreases activity
ISO Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCB1 mRNA
Haloperidol results in decreased activity of ABCB1 protein
CTD PMID:15946544, PMID:16810505 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression
ISO Haloperidol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCC1 mRNA
CTD PMID:15946544 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a decreases expression EXP Haloperidol results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr12:40,533,731...40,536,632
Ensembl chr12:40,533,632...40,536,620
JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions
ISO ADCY5 protein affects the susceptibility to Haloperidol
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol]
CTD PMID:12223546 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression ISO Haloperidol affects the expression of ADCYAP1R1 mRNA CTD PMID:27900577 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Adora2a adenosine A2a receptor affects response to substance ISO ADORA2A protein affects the susceptibility to Haloperidol CTD PMID:11172060 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr20:4,369,399...4,378,272
Ensembl chr20:4,369,178...4,378,269
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Haloperidol results in decreased expression of AKT1 mRNA CTD PMID:15860345 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP Haloperidol results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Haloperidol results in increased expression of ALDOA mRNA CTD PMID:15860345 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP Haloperidol results in increased expression of ALDOC mRNA CTD PMID:15860345 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 decreases expression EXP Haloperidol results in decreased expression of AP2A2 mRNA CTD PMID:15860345 NCBI chr 1:214,534,217...214,607,497
Ensembl chr 1:214,534,284...214,606,169
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Haloperidol affects the expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Apod apolipoprotein D increases expression ISO Haloperidol results in increased expression of APOD mRNA CTD PMID:14647396 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression
multiple interactions
EXP Haloperidol results in increased expression of ARC mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of ARC mRNA]
CTD PMID:18208916, PMID:19695244 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression EXP Haloperidol results in decreased expression of ARF1 mRNA CTD PMID:15860345 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression EXP Haloperidol results in decreased expression of ARF3 mRNA CTD PMID:15860345 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression EXP Haloperidol results in decreased expression of ARL3 mRNA CTD PMID:15860345 NCBI chr 1:266,287,015...266,333,099
Ensembl chr 1:266,287,017...266,333,105
JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A decreases expression EXP Haloperidol results in decreased expression of ARL5A mRNA CTD PMID:15860345 NCBI chr 3:37,922,544...37,947,434
Ensembl chr 3:37,924,793...37,947,283
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Haloperidol results in increased expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Haloperidol results in decreased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Haloperidol results in decreased expression of ATP1A1 mRNA CTD PMID:15860345 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression EXP Haloperidol results in decreased expression of ATP1A3 mRNA CTD PMID:15860345 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Haloperidol results in increased expression of ATP1B1 mRNA CTD PMID:15860345 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Haloperidol results in decreased expression of ATP1B2 mRNA CTD PMID:15860345 NCBI chr10:56,205,622...56,211,879
Ensembl chr10:56,205,625...56,211,891
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Haloperidol results in increased expression of ATP1B3 mRNA CTD PMID:15860345 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B2 mRNA CTD PMID:16465460 NCBI chr16:22,326,537...22,350,143
Ensembl chr16:22,326,529...22,350,155
JBrowse link
G Axin2 axin 2 decreases expression EXP Haloperidol results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
EXP Haloperidol results in decreased expression of BAX protein
Haloperidol results in increased expression of BAX mRNA; Haloperidol results in increased expression of BAX protein
CTD PMID:16462815, PMID:17069804 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Haloperidol results in increased expression of BCL2 protein CTD PMID:17069804 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression
EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]
Haloperidol results in increased expression of BCL2L1 protein
CTD PMID:16462815, PMID:17805306 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
decreases expression
EXP
ISO
BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; Haloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]
Haloperidol results in increased expression of BDNF mRNA
Haloperidol results in increased expression of BDNF protein
Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Haloperidol results in decreased expression of BDNF mRNA; Haloperidol results in decreased expression of BDNF protein
CTD PMID:11488957, PMID:12393228, PMID:12478621, PMID:15168214, PMID:17442543, PMID:17805306, PMID:18208916, PMID:20554863, PMID:29182611 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like affects expression EXP Haloperidol affects the expression of BET1L mRNA CTD PMID:15860345 NCBI chr 1:213,602,836...213,606,507
Ensembl chr 1:213,602,850...213,605,643
JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO Haloperidol results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases expression EXP
ISO
Haloperidol results in decreased expression of CACNA1A mRNA CTD PMID:14647396, PMID:16715494 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Haloperidol affects the activity of CALCA protein CTD PMID:10075105 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm2 calmodulin 2 increases expression EXP Haloperidol results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
increases expression
decreases expression
EXP Haloperidol results in decreased expression of and results in decreased phosphorylation of CAMK2A protein
Haloperidol results in increased expression of CAMK2A mRNA
Haloperidol results in decreased expression of CAMK2A protein
CTD PMID:15860345, PMID:18061412, PMID:19289156 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Haloperidol results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression EXP Haloperidol results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression
increases expression
EXP Haloperidol results in decreased expression of CAMK4 protein
Haloperidol results in increased expression of CAMK4 mRNA
CTD PMID:15860345, PMID:19289156 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr10:59,585,023...59,608,180
Ensembl chr10:59,585,072...59,608,165
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression EXP Haloperidol results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
EXP BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:15168214, PMID:17805306, PMID:18590723 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity
EXP Carvedilol inhibits the reaction [Haloperidol results in decreased expression of CAT protein]; Haloperidol results in decreased activity of and results in decreased expression of CAT protein; Zolpidem inhibits the reaction [Haloperidol results in decreased activity of CAT] CTD PMID:12010767, PMID:12482469, PMID:16564057, PMID:17513028 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cck cholecystokinin increases expression EXP Haloperidol results in increased expression of CCK mRNA CTD PMID:10974607 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Haloperidol results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Haloperidol results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Haloperidol results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838
JBrowse link
G Cdc42 cell division cycle 42 increases expression EXP Haloperidol results in increased expression of CDC42 mRNA CTD PMID:15860345 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Haloperidol results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP Haloperidol results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression ISO Haloperidol results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 4:70,269,414...70,331,313
Ensembl chr 4:70,252,366...70,330,803
JBrowse link
G Chn1 chimerin 1 decreases expression ISO Haloperidol results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 3:60,512,360...60,668,413
Ensembl chr 3:60,513,077...60,611,924
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects response to substance ISO CHRM4 affects the susceptibility to Haloperidol CTD PMID:21269601 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Cldn11 claudin 11 decreases expression ISO Haloperidol results in decreased expression of CLDN11 mRNA CTD PMID:17177202 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clta clathrin, light chain A affects expression EXP Haloperidol affects the expression of CLTA mRNA CTD PMID:15860345 NCBI chr 5:59,490,689...59,509,139
Ensembl chr 5:59,491,096...59,509,138
JBrowse link
G Cltb clathrin, light chain B decreases expression EXP Haloperidol results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression ISO Haloperidol results in decreased expression of CNP mRNA CTD PMID:17177202 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Coil coilin increases expression EXP Haloperidol results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr10:76,320,676...76,336,169
Ensembl chr10:76,320,041...76,341,418
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 increases expression EXP Haloperidol results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr 1:263,733,887...263,762,758
Ensembl chr 1:263,733,519...263,762,785
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Amphetamine affects the reaction [Haloperidol results in increased activity of CREB1 protein modified form]
CTD PMID:12125044, PMID:12871586 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Haloperidol results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression EXP Haloperidol results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr 2:25,141,471...25,153,334
Ensembl chr 2:25,141,471...25,153,334
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Haloperidol results in decreased expression of CRY1 mRNA CTD PMID:27746588 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Haloperidol results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Cst3 cystatin C increases expression ISO Haloperidol results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Haloperidol results in decreased expression of CTNNB1 mRNA
Haloperidol results in increased expression of CTNNB1 protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]
CTD PMID:16144542, PMID:18797397 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctrl chymotrypsin-like increases expression EXP Haloperidol results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr19:37,905,864...37,907,714
Ensembl chr19:37,905,864...37,907,714
JBrowse link
G Ctsk cathepsin K increases expression EXP Haloperidol results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance ISO CYP2D6 protein polymorphism affects the susceptibility to Haloperidol CTD PMID:15538130 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO Haloperidol results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr13:83,578,730...83,680,330
Ensembl chr13:83,579,036...83,680,207
JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO
EXP
Haloperidol results in increased expression of DCLK1 mRNA CTD PMID:15860345, PMID:18797397 NCBI chr 2:144,646,255...144,939,389
Ensembl chr 2:144,646,308...144,936,927
JBrowse link
G Dennd10 DENN domain containing 10 increases expression EXP Haloperidol results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr 1:282,188,080...282,211,588
Ensembl chr 1:282,188,110...282,210,580
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Haloperidol results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression EXP Haloperidol results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr 7:3,143,826...3,170,764
Ensembl chr 7:3,143,827...3,170,146
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression EXP Haloperidol results in decreased expression of DLAT mRNA CTD PMID:15860345 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dpf1 double PHD fingers 1 increases expression ISO Haloperidol results in increased expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 1:87,248,448...87,258,070
Ensembl chr 1:87,248,489...87,258,070
JBrowse link
G Drd1 dopamine receptor D1 affects binding
increases expression
decreases expression
affects activity
ISO
EXP
Haloperidol binds to DRD1 protein
Haloperidol results in increased expression of DRD1 protein
Haloperidol results in decreased expression of DRD1 mRNA
Haloperidol affects the activity of DRD1 protein
CTD PMID:8750706, PMID:8794996, PMID:12887421, PMID:16983399, PMID:23611293 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 affects binding
affects activity
multiple interactions
increases expression
affects response to substance
ISO
EXP
DRD2 protein binds to Haloperidol; DRD2 protein binds to Haloperidol analog; Haloperidol binds to DRD2 protein
Haloperidol affects the activity of DRD2 protein
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; cyclo(leucylglycine) inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]; felbamate inhibits the reaction [Haloperidol affects the activity of DRD2 protein]; Haloperidol binds to and results in decreased activity of DRD2 protein; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [iodosulpride binds to DRD2 protein]; Haloperidol inhibits the reaction [Spiperone binds to DRD2 protein]; Haloperidol promotes the reaction [Dopamine binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein]
Haloperidol results in increased expression of DRD2; Haloperidol results in increased expression of DRD2 mRNA; Haloperidol results in increased expression of DRD2 protein
Haloperidol binds to DRD2; Haloperidol binds to DRD2 protein; Haloperidol binds to DRD2 protein alternative form
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Ethanol; [Haloperidol results in increased expression of DRD2 protein] which results in decreased susceptibility to Pentobarbital; Haloperidol binds to and results in decreased activity of DRD2 protein
DRD2 affects the susceptibility to Haloperidol; DRD2 protein affects the susceptibility to Haloperidol
Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 mRNA]; Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]
CTD PMID:1351265, PMID:1361536, PMID:1380082, PMID:2945998, PMID:7845605, PMID:7878047, PMID:8115415, PMID:8200438, PMID:8794996, PMID:9109525, PMID:9808703, PMID:10720636, PMID:10936494, PMID:11172060, PMID:11927170, PMID:11997696, PMID:12191584, PMID:12476322, PMID:14552778, PMID:15716360, PMID:16033416, PMID:16144542, PMID:18295747, PMID:19120057, PMID:20361897, PMID:20730801, PMID:23611293 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 affects binding ISO DRD3 protein binds to Haloperidol analog CTD PMID:14552778 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 affects activity ISO Haloperidol affects the activity of DRD4 protein CTD PMID:23611293 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Drp2 dystrophin related protein 2 increases expression EXP Haloperidol results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:105,239,623...105,290,233
Ensembl chr  X:105,239,620...105,289,808
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance
ISO DTNBP1 gene polymorphism results in increased susceptibility to Haloperidol
DTNBP1 protein affects the susceptibility to Haloperidol
CTD PMID:19369910 NCBI chr17:20,090,136...20,182,332
Ensembl chr17:20,090,246...20,182,206
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Haloperidol results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Haloperidol results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 multiple interactions
increases expression
EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein] CTD PMID:16144542 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Egr1 early growth response 1 affects expression
multiple interactions
increases expression
EXP
ISO
Haloperidol affects the expression of EGR1 protein
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
Haloperidol results in increased expression of EGR1 mRNA; Haloperidol results in increased expression of EGR1 protein
CTD PMID:12243769, PMID:16452686, PMID:17028028, PMID:17913375, PMID:18208916, PMID:19695244, PMID:20184921 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 affects expression
increases expression
decreases expression
ISO
EXP
Haloperidol affects the expression of EGR2 mRNA
Haloperidol results in increased expression of EGR2 mRNA
Haloperidol results in decreased expression of EGR2 protein
CTD PMID:17028028, PMID:18208916, PMID:19401217 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation
multiple interactions
ISO
EXP
Haloperidol results in increased phosphorylation of ELK1 protein
SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
Nifedipine affects the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
CTD PMID:12871586, PMID:17913375 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Eno1 enolase 1 increases expression EXP Haloperidol results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Epo erythropoietin multiple interactions EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:17805306 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP Haloperidol results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression
multiple interactions
EXP Haloperidol results in increased expression of ERBB4 protein
Haloperidol results in increased expression of and results in increased phosphorylation of ERBB4 protein
CTD PMID:18184445, PMID:26961615 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Fabp3 fatty acid binding protein 3 affects response to substance ISO FABP3 affects the susceptibility to Haloperidol CTD PMID:20181611 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fasn fatty acid synthase increases expression ISO Haloperidol results in increased expression of FASN mRNA CTD PMID:16027736 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
ISO
EXP
8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; ifenprodil inhibits the reaction [Haloperidol results in increased expression of FOS protein]; tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; traxoprodil mesylate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]]
Haloperidol results in increased expression of FOS mRNA; Haloperidol results in increased expression of FOS protein
Haloperidol results in decreased expression of FOS mRNA; Haloperidol results in decreased expression of FOS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Dronabinol promotes the reaction [Haloperidol results in increased expression of FOS protein]; Nifedipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Nimodipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Theophylline inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]
CTD PMID:1393566, PMID:9571656, PMID:9748542, PMID:10199625, PMID:10435392, PMID:11166331, PMID:11409749, PMID:11440804, PMID:11516571, PMID:11602683, PMID:11997696, PMID:12093589, PMID:12125044, PMID:12243769, PMID:12464447, PMID:15120589, PMID:15140647, PMID:17028028, PMID:17913375, PMID:18208916, PMID:18295747, PMID:18521575, PMID:18585397, PMID:18789920, PMID:19352073, PMID:19695244 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Haloperidol results in increased expression of FOSB protein alternative form
Haloperidol results in increased expression of FOSB modified form; Haloperidol results in increased expression of FOSB mRNA; Haloperidol results in increased expression of FOSB protein
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOSB mRNA]
CTD PMID:8714707, PMID:11180499, PMID:12243769, PMID:15579174, PMID:19695244, PMID:24067299 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression
EXP Amphetamine affects the reaction [Haloperidol results in increased expression of FOSL1 protein]
Haloperidol results in increased expression of FOSL1 mRNA; Haloperidol results in increased expression of FOSL1 protein
CTD PMID:12125044, PMID:18208916 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Haloperidol results in increased expression of FOSL2 mRNA CTD PMID:12243769 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
increases phosphorylation
affects response to substance
ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein]
Haloperidol results in increased phosphorylation of FYN protein
FYN protein affects the susceptibility to Haloperidol
CTD PMID:16407246 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression ISO Haloperidol results in decreased expression of GABRA1 mRNA CTD PMID:18797397 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression EXP Haloperidol results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
increases expression
decreases expression
EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein
Haloperidol results in increased expression of GAD1 mRNA
Haloperidol results in decreased expression of GAD1 mRNA; Haloperidol results in decreased expression of GAD1 protein
CTD PMID:12887421, PMID:14519413, PMID:15061247, PMID:15967061, PMID:18923069, PMID:19359144 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression
increases expression
EXP Haloperidol results in decreased expression of GAD2 mRNA; Haloperidol results in decreased expression of GAD2 protein
Haloperidol results in increased expression of GAD2 mRNA
CTD PMID:18923069, PMID:19359144 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Haloperidol results in increased expression of GAPDH mRNA CTD PMID:15860345 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Haloperidol results in increased expression of GDPD3 mRNA CTD PMID:17175557 NCBI chr 1:198,199,032...198,209,178
Ensembl chr 1:198,199,622...198,209,150
JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression EXP Haloperidol results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Haloperidol results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Haloperidol results in decreased expression of GLUL mRNA CTD PMID:15860345 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression EXP Haloperidol results in decreased expression of GNA12 mRNA CTD PMID:15860345 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression EXP Haloperidol results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 4:13,405,136...13,486,866
Ensembl chr 4:13,405,136...13,485,883
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Haloperidol results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression EXP Haloperidol results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnas GNAS complex locus decreases expression EXP Haloperidol results in decreased expression of GNAS mRNA CTD PMID:15860345 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein] CTD PMID:18603625 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression EXP Haloperidol affects the expression of GOT2 mRNA CTD PMID:15860345 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Haloperidol results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Haloperidol results in decreased expression of GRIA1 mRNA CTD PMID:15860345 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP Haloperidol results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 increases expression EXP Haloperidol results in increased expression of GRIK4 mRNA CTD PMID:15860345 NCBI chr 8:46,804,134...47,237,546
Ensembl chr 8:46,806,147...47,094,352
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO
EXP
Haloperidol results in increased expression of GRIK5 mRNA CTD PMID:14647396, PMID:15860345 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
increases expression
EXP Haloperidol results in decreased expression of GRIN1 mRNA
Haloperidol results in increased expression of GRIN1 mRNA
CTD PMID:12020038 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP Haloperidol results in decreased expression of GRIN2A mRNA; Haloperidol results in decreased expression of GRIN2A protein CTD PMID:12608697, PMID:15860345, PMID:18061412 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
increases phosphorylation
ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein] CTD PMID:16407246 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Haloperidol results in increased expression of GRIN2C mRNA CTD PMID:15860345 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression EXP Haloperidol results in decreased expression of GRIN2D mRNA CTD PMID:18923069 NCBI chr 1:101,819,068...101,859,146
Ensembl chr 1:101,820,461...101,856,881
JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B increases expression EXP Haloperidol results in increased expression of GRIN3B mRNA CTD PMID:15860345 NCBI chr 7:12,764,993...12,771,310
Ensembl chr 7:12,764,993...12,771,310
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Haloperidol results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574
JBrowse link
G Grm1 glutamate metabotropic receptor 1 increases expression EXP Haloperidol results in increased expression of GRM1 mRNA CTD PMID:15860345 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression EXP Haloperidol results in increased expression of GRM2 mRNA CTD PMID:18923069 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions
EXP Haloperidol results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]
CTD PMID:16144542 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression
EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]
Haloperidol results in increased expression of GSK3B mRNA; Haloperidol results in increased expression of GSK3B protein
CTD PMID:16144542, PMID:19359144 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Haloperidol results in increased expression of GSTM1 mRNA CTD PMID:15860345 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Haloperidol results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases expression
ISO Haloperidol inhibits the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of GSTP1 mRNA
CTD PMID:15946544 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression ISO Haloperidol results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 increases expression ISO Haloperidol results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 2:198,381,678...198,382,247
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity
increases expression
multiple interactions
ISO Haloperidol results in increased activity of HMGCR protein
Haloperidol results in increased expression of HMGCR mRNA
[Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides
CTD PMID:16027736, PMID:17052361 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Haloperidol results in increased expression of HMGCS1 mRNA CTD PMID:16027736, PMID:17052361 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions
increases expression
EXP Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447, PMID:15860345, PMID:20147574 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Hpcal4 hippocalcin-like 4 decreases expression EXP Haloperidol results in decreased expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 5:140,870,127...140,882,242
Ensembl chr 5:140,870,140...140,882,244
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression
multiple interactions
ISO Haloperidol results in decreased expression of HSPG2 mRNA
HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine]
CTD PMID:20072119 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D decreases expression EXP Haloperidol results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions
EXP
ISO
Haloperidol binds to HTR2A protein
[Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein
CTD PMID:7520908, PMID:12191584, PMID:15380371 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C decreases expression EXP Haloperidol results in decreased expression of HTR2C mRNA CTD PMID:17868938 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
increases expression
EXP Haloperidol results in decreased expression of ID2 mRNA
Haloperidol results in increased expression of ID2 mRNA
CTD PMID:12437575 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Ilkap ILK associated serine/threonine phosphatase decreases expression EXP Haloperidol results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 9:98,514,599...98,536,586
Ensembl chr 9:98,514,584...98,536,581
JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Haloperidol results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Haloperidol results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression
EXP Haloperidol results in increased expression of JUN mRNA; Haloperidol results in increased expression of JUN protein
Haloperidol results in decreased expression of JUN mRNA
CTD PMID:12093589, PMID:12125044, PMID:15860345, PMID:18208916 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression
EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]
Haloperidol results in decreased expression of JUNB mRNA
CTD PMID:12093589, PMID:19695244 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 increases expression ISO Haloperidol results in increased expression of KCNA1 mRNA; Haloperidol results in increased expression of KCNA1 protein CTD PMID:18797397 NCBI chr 4:159,190,781...159,192,526
Ensembl chr 4:159,190,804...159,192,526
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 decreases expression ISO Haloperidol results in decreased expression of KCNAB1 mRNA CTD PMID:18797397 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Haloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Haloperidol results in decreased activity of KCNH2 protein
CTD PMID:15671647, PMID:16278312, PMID:16494862, PMID:19583963, PMID:21158687 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression ISO Haloperidol results in decreased expression of KCNIP3 mRNA; Haloperidol results in decreased expression of KCNIP3 protein CTD PMID:18797397 NCBI chr 3:120,023,062...120,087,650
Ensembl chr 3:120,023,917...120,087,136
JBrowse link
G Klc1 kinesin light chain 1 decreases expression ISO Haloperidol results in decreased expression of KLC1 mRNA CTD PMID:18797397 NCBI chr 6:136,330,151...136,373,716
Ensembl chr 6:136,330,383...136,373,721
JBrowse link
G Kmt2a lysine methyltransferase 2A decreases expression ISO Haloperidol results in decreased expression of KMT2A mRNA CTD PMID:14647396 NCBI chr 8:49,110,407...49,185,872
Ensembl chr 8:49,114,990...49,158,971
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP Haloperidol results in increased expression of KRAS mRNA CTD PMID:15860345 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression ISO Haloperidol results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 2:243,160,821...243,173,057
Ensembl chr 2:243,160,917...243,173,048
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression
increases expression
ISO
EXP
Haloperidol results in decreased expression of LDHB mRNA
Haloperidol results in increased expression of LDHB mRNA
CTD PMID:15860345, PMID:16465460 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G LOC103690091 proSAAS increases expression ISO Haloperidol results in increased expression of PCSK1N mRNA CTD PMID:14647396 NCBI chr  X:15,324,261...15,328,617 JBrowse link
G Mag myelin-associated glycoprotein decreases expression ISO Haloperidol results in decreased expression of MAG mRNA CTD PMID:17177202 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Map1a microtubule-associated protein 1A increases expression EXP Haloperidol results in increased expression of MAP1A mRNA CTD PMID:15860345 NCBI chr 3:113,251,918...113,272,193
Ensembl chr 3:113,251,778...113,272,186
JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Haloperidol results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression
increases expression
EXP
ISO
Haloperidol results in decreased expression of MAP2K2 mRNA
Haloperidol results in increased expression of MAP2K2 mRNA
CTD PMID:14647396, PMID:15860345 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression EXP Haloperidol results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP Haloperidol results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP Haloperidol results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases expression
multiple interactions
ISO
EXP
Haloperidol results in increased phosphorylation of MAPK1 protein
Haloperidol results in decreased expression of MAPK1 mRNA
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]
CTD PMID:12871586, PMID:15860345 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Haloperidol affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Haloperidol results in increased phosphorylation of MAPK3 protein
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]
CTD PMID:12871586 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression EXP Haloperidol affects the expression of MAPK6 mRNA CTD PMID:15860345 NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation EXP Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 affects expression EXP Haloperidol affects the expression of MAPK9 mRNA CTD PMID:15860345 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Haloperidol results in decreased expression of MAS1 mRNA CTD PMID:16715494 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mbp myelin basic protein decreases expression ISO Haloperidol results in decreased expression of MBP mRNA CTD PMID:17177202 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 affects binding ISO Haloperidol binds to MCHR1 protein CTD PMID:16983399 NCBI chr 7:122,456,846...122,459,324
Ensembl chr 7:122,456,799...122,459,960
JBrowse link
G Mog myelin oligodendrocyte glycoprotein decreases expression ISO Haloperidol results in decreased expression of MOG mRNA CTD PMID:17177202 NCBI chr20:2,003,871...2,014,284
Ensembl chr20:2,004,052...2,014,286
JBrowse link
G Ncan neurocan decreases expression ISO Haloperidol results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr16:21,050,243...21,076,707
Ensembl chr16:21,050,243...21,076,707
JBrowse link
G Ncl nucleolin increases expression ISO Haloperidol results in increased expression of NCL mRNA CTD PMID:14647396 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Haloperidol results in decreased expression of NEDD4 mRNA CTD PMID:18797397 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP Haloperidol results in decreased expression of NFKB1 protein CTD PMID:16500086 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Haloperidol results in decreased expression of NGFR mRNA CTD PMID:16513140 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO Haloperidol results in increased expression of NOP53 mRNA CTD PMID:14647396 NCBI chr 1:77,836,522...77,843,991
Ensembl chr 1:77,836,196...77,844,189
JBrowse link
G Nppa natriuretic peptide A affects activity EXP Haloperidol affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nptx2 neuronal pentraxin 2 decreases expression EXP Haloperidol results in decreased expression of NPTX2 mRNA CTD PMID:18208916 NCBI chr12:12,014,638...12,025,547
Ensembl chr12:12,013,911...12,025,549
JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
decreases expression
EXP Haloperidol promotes the reaction [Amphetamine results in decreased expression of NPY protein]
Haloperidol results in increased expression of NPY protein
Haloperidol results in decreased expression of NPY mRNA
CTD PMID:7644023, PMID:15985714, PMID:16516965 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Haloperidol results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Haloperidol results in increased expression of NR1D1 mRNA CTD PMID:11564422 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects response to substance
multiple interactions
increases expression
decreases expression
ISO
EXP
NR4A1 affects the susceptibility to Haloperidol
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]
Haloperidol results in decreased expression of NR4A1 mRNA
CTD PMID:10987852, PMID:11564422, PMID:14603264, PMID:19695244 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Haloperidol results in increased expression of NR4A3 mRNA CTD PMID:19695244 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP Haloperidol results in increased expression of NRG1 protein CTD PMID:18184445, PMID:26961615 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP Haloperidol results in decreased expression of NSF mRNA CTD PMID:15860345 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nts neurotensin multiple interactions
increases expression
ISO
EXP
SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of NTS mRNA; Haloperidol results in increased expression of NTS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]; Theophylline inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]
CTD PMID:10199625, PMID:11120399, PMID:11602683, PMID:12887421, PMID:14603264, PMID:14698760 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Numbl NUMB-like, endocytic adaptor protein decreases expression ISO Haloperidol results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 1:84,067,841...84,091,659
Ensembl chr 1:84,067,938...84,091,671
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Haloperidol results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 affects response to substance ISO OPRL1 affects the susceptibility to Haloperidol CTD PMID:16237164 NCBI chr 3:177,223,779...177,231,663
Ensembl chr 3:177,225,737...177,231,663
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:20184921 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression ISO Haloperidol results in increased expression of OSBPL8 mRNA CTD PMID:14647396 NCBI chr 7:53,878,906...54,030,110
Ensembl chr 7:53,878,610...54,027,892
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Haloperidol results in increased expression of PARK7 mRNA CTD PMID:14647396 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Pde10a phosphodiesterase 10A increases expression EXP Haloperidol results in increased expression of PDE10A mRNA; Haloperidol results in increased expression of PDE10A protein CTD PMID:18222493 NCBI chr 1:52,360,296...52,544,448
Ensembl chr 1:52,360,296...52,544,450
JBrowse link
G Pde1b phosphodiesterase 1B increases expression EXP
ISO
Haloperidol results in increased expression of PDE1B mRNA; Haloperidol results in increased expression of PDE1B protein CTD PMID:14647396, PMID:18222493 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Haloperidol results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748
JBrowse link
G Penk proenkephalin multiple interactions
increases expression
ISO
EXP
3,4-dicarboxyphenylglycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; Docosahexaenoic Acids inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Tretinoin inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
Haloperidol results in increased expression of PENK mRNA; Haloperidol results in increased expression of PENK protein
1-aminocyclopentane-1,2,4-tricarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 1-aminoindan-1,5-dicarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 2-(2,3-dicarboxycyclopropyl)glycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
CTD PMID:3838946, PMID:7637876, PMID:12373537, PMID:12727308, PMID:12834887, PMID:12887421, PMID:14603264, PMID:14642644, PMID:15215559, PMID:17224239 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Per1 period circadian regulator 1 increases expression ISO Haloperidol results in increased expression of PER1 mRNA CTD PMID:27746588 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression ISO Haloperidol results in increased expression of PFDN5 mRNA CTD PMID:14647396 NCBI chr 7:143,924,662...143,929,400
Ensembl chr 7:143,924,662...143,929,397
JBrowse link
G Pfkp phosphofructokinase, platelet increases expression EXP Haloperidol results in increased expression of PFKP mRNA CTD PMID:15860345 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression EXP Haloperidol results in increased expression of PGK1 mRNA CTD PMID:15860345 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases expression ISO Haloperidol results in increased expression of PHACTR1 mRNA CTD PMID:14647396 NCBI chr17:23,245,423...23,761,207 JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression EXP Haloperidol results in decreased expression of PICALM mRNA CTD PMID:15860345 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression EXP Haloperidol results in decreased expression of PIK3R3 mRNA CTD PMID:16715494 NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression EXP Haloperidol results in decreased expression of PKIB mRNA CTD PMID:15860345 NCBI chr20:40,616,868...40,712,598
Ensembl chr20:40,618,128...40,712,592
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO Haloperidol results in decreased expression of PLP1 mRNA CTD PMID:17177202, PMID:18797397 NCBI chr  X:107,494,326...107,511,355
Ensembl chr  X:107,496,072...107,511,348
JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A decreases expression EXP Haloperidol results in decreased expression of PPM1A mRNA CTD PMID:15860345 NCBI chr 6:94,433,658...94,484,979
Ensembl chr 6:94,429,068...94,484,351
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression EXP Haloperidol results in decreased expression of PPM1B mRNA CTD PMID:15860345 NCBI chr 6:8,219,385...8,280,127
Ensembl chr 6:8,218,696...8,280,124
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP1CB mRNA CTD PMID:15860345 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Haloperidol results in decreased expression of PPP1CC mRNA CTD PMID:15860345 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A decreases expression EXP Haloperidol results in decreased expression of PPP1R1A mRNA CTD PMID:15860345 NCBI chr 7:145,146,480...145,154,131
Ensembl chr 7:145,146,481...145,154,131
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases phosphorylation ISO Haloperidol results in increased phosphorylation of PPP1R1B protein CTD PMID:12871586 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases expression EXP Haloperidol results in decreased expression of PPP1R2 mRNA CTD PMID:15860345 NCBI chr11:72,748,789...73,034,683
Ensembl chr11:73,022,063...73,034,682
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B decreases expression EXP Haloperidol results in decreased expression of PPP1R9B protein CTD PMID:16844384 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha decreases expression EXP Haloperidol results in decreased expression of PPP2CA mRNA CTD PMID:15860345 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP2CB mRNA CTD PMID:15860345 NCBI chr16:62,273,276...62,294,767
Ensembl chr16:62,273,276...62,294,769
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP Haloperidol results in increased expression of PPP2R1A mRNA CTD PMID:15860345 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases expression EXP Haloperidol results in decreased expression of PPP2R2A mRNA CTD PMID:15860345 NCBI chr15:43,673,958...43,733,182
Ensembl chr15:43,673,960...43,733,182
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression
EXP [Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Haloperidol results in decreased expression of PPP3CA mRNA; Haloperidol results in decreased expression of PPP3CA protein
CTD PMID:16033416 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit decreases expression ISO Haloperidol results in decreased expression of PPP5C mRNA CTD PMID:14647396 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP Haloperidol results in increased expression of PRKACA mRNA CTD PMID:15860345 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases expression EXP Haloperidol results in increased expression of PRKACB mRNA CTD PMID:15860345 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions
increases expression
EXP Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein]
Haloperidol results in increased expression of PRKAR2A mRNA; Haloperidol results in increased expression of PRKAR2A protein
CTD PMID:11907174 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions
increases expression
decreases expression
EXP Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein]
Haloperidol results in increased expression of PRKAR2B mRNA; Haloperidol results in increased expression of PRKAR2B protein
Haloperidol results in decreased expression of PRKAR2B mRNA
CTD PMID:11907174, PMID:15860345 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases expression
EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein
Haloperidol results in increased expression of PRKCB mRNA
CTD PMID:15860345, PMID:15967061 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkce protein kinase C, epsilon increases expression EXP Haloperidol results in increased expression of PRKCE mRNA CTD PMID:15860345 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP Haloperidol results in increased expression of PRKCZ mRNA CTD PMID:15860345 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Prl prolactin affects expression
increases secretion
multiple interactions
increases expression
ISO
EXP
Haloperidol affects the expression of PRL protein
Haloperidol results in increased secretion of PRL protein
Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Dopamine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [talipexole results in decreased secretion of PRL protein]; LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- inhibits the reaction [Haloperidol results in increased expression of PRL protein]; Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein]
CTD PMID:1304992, PMID:1380082, PMID:2136057, PMID:3019639, PMID:3158510, PMID:3883215, PMID:3906589, PMID:7018927, PMID:7214106, PMID:7348089, PMID:7670571, PMID:8613910, PMID:8915564, PMID:9090331, PMID:9128918, PMID:9265911, PMID:9265916, PMID:9376336, PMID:9572212, PMID:10661492, PMID:11048906, PMID:11071396, PMID:11997696, PMID:15289996, PMID:15638391, PMID:16282852, PMID:18521575 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prpf38b pre-mRNA processing factor 38B decreases expression ISO Haloperidol results in decreased expression of PRPF38B mRNA CTD PMID:14647396 NCBI chr 2:211,706,245...211,715,271
Ensembl chr 2:211,706,228...211,715,311
JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression ISO Haloperidol results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr20:5,139,881...5,155,371
Ensembl chr20:5,139,882...5,155,293
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression EXP Haloperidol results in decreased expression of PSMB9 mRNA CTD PMID:16452686 NCBI chr20:3,973,424...3,978,845
Ensembl chr20:3,973,420...3,978,845
JBrowse link
G Ptms parathymosin increases expression ISO Haloperidol results in increased expression of PTMS mRNA CTD PMID:14647396 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507
JBrowse link
G Pvalb parvalbumin multiple interactions EXP Haloperidol inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Qk quaking increases expression ISO Haloperidol results in increased expression of QKI mRNA alternative form CTD PMID:19335891 NCBI chr 1:50,983,647...51,050,692 JBrowse link
G Rab10 RAB10, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB10 mRNA CTD PMID:15860345 NCBI chr 6:27,668,387...27,721,120
Ensembl chr 6:27,668,403...27,721,120
JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB11A mRNA CTD PMID:15860345 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719
JBrowse link
G Rab12 RAB12, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB12 mRNA CTD PMID:12437575 NCBI chr 9:114,683,985...114,709,613
Ensembl chr 9:114,684,039...114,709,546
JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB28 mRNA CTD PMID:15860345 NCBI chr14:73,888,968...73,963,209
Ensembl chr14:73,889,213...73,963,202
JBrowse link
G Rab4a RAB4A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB4A mRNA CTD PMID:15860345 NCBI chr19:56,585,598...56,613,078
Ensembl chr19:56,585,767...56,613,075
JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB6A mRNA CTD PMID:15860345 NCBI chr 1:165,624,973...165,664,201
Ensembl chr 1:165,625,058...165,664,192
JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB7A mRNA CTD PMID:15860345 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB8A mRNA CTD PMID:15860345 NCBI chr16:19,355,047...19,376,776
Ensembl chr16:19,355,048...19,376,776
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Haloperidol results in increased expression of RAC1 mRNA CTD PMID:15860345 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Haloperidol results in increased expression of RALA mRNA CTD PMID:15860345 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664
JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Haloperidol results in increased expression of RALB mRNA CTD PMID:15860345 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAP1B mRNA CTD PMID:15860345 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO Haloperidol results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rarb retinoic acid receptor, beta increases expression EXP Haloperidol results in increased expression of RARB mRNA alternative form CTD PMID:11564422 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization EXP Haloperidol affects the localization of RASGRF1 protein CTD PMID:17092607 NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression EXP Haloperidol results in decreased expression of RASGRP1 mRNA CTD PMID:15860345 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP Haloperidol results in increased expression of RELA protein CTD PMID:18554768, PMID:18590723 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Reln reelin decreases expression EXP Haloperidol results in decreased expression of RELN mRNA; Haloperidol results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP Haloperidol results in increased expression of RGS2 mRNA CTD PMID:11409749, PMID:11516571 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP Haloperidol results in increased expression of RGS4 mRNA CTD PMID:15860345 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Haloperidol results in increased expression of RGS8 mRNA CTD PMID:15860345 NCBI chr13:71,086,654...71,141,820
Ensembl chr13:71,086,745...71,141,075
JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Haloperidol CTD PMID:15728856 NCBI chr10:97,509,971...97,582,188
Ensembl chr10:97,509,971...97,582,188
JBrowse link
G Rhoa ras homolog family member A decreases expression EXP Haloperidol results in decreased expression of RHOA mRNA CTD PMID:15860345 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 decreases expression EXP Haloperidol results in decreased expression of RIMS1 mRNA CTD PMID:15860345 NCBI chr 9:28,440,408...28,973,246
Ensembl chr 9:28,442,229...28,973,246
JBrowse link
G Rorb RAR-related orphan receptor B decreases expression EXP Haloperidol results in decreased expression of RORB mRNA CTD PMID:11564422 NCBI chr 1:234,252,757...234,442,597
Ensembl chr 1:234,252,757...234,435,839
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression ISO Haloperidol results in increased expression of RPLP2 mRNA CTD PMID:14647396 NCBI chr 1:214,428,280...214,430,551
Ensembl chr 1:214,428,526...214,430,515
JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Haloperidol results in increased expression of RPS10 mRNA CTD PMID:14647396 NCBI chr20:7,215,762...7,220,331
Ensembl chr20:7,215,774...7,219,548
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP Haloperidol results in increased expression of RRAD mRNA CTD PMID:15860345 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Rtn4 reticulon 4 decreases expression ISO Haloperidol results in decreased expression of RTN4 mRNA CTD PMID:18797397 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance
increases expression
ISO
EXP
RXRG protein affects the susceptibility to Haloperidol
Haloperidol results in increased expression of RXRG mRNA alternative form
CTD PMID:10336693, PMID:11564422 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Haloperidol results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Haloperidol results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:46,525,406...46,537,014
Ensembl chr 8:46,525,400...46,537,050
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Haloperidol results in increased expression of SCD mRNA CTD PMID:16027736 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Serpina3m serpin family A member 3M increases expression ISO Haloperidol results in increased expression of SERPINA3 mRNA CTD PMID:17175557 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO Haloperidol results in decreased expression of SERPINI1 mRNA CTD PMID:18797397 NCBI chr 2:174,013,058...174,111,693
Ensembl chr 2:174,013,288...174,111,752
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Haloperidol results in increased expression of SGK1 mRNA CTD PMID:16452686 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Haloperidol results in increased expression of SLC17A6 mRNA; Haloperidol results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:106,980,463...107,038,717
Ensembl chr 1:106,998,623...107,038,704
JBrowse link
G Slc17a8 solute carrier family 17 member 8 affects response to substance ISO SLC17A8 protein affects the susceptibility to Haloperidol CTD PMID:18278042 NCBI chr 7:30,215,231...30,274,993
Ensembl chr 7:30,216,104...30,274,984
JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding ISO Haloperidol binds to SLC18A2 protein CTD PMID:7912402 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression EXP Haloperidol results in decreased expression of SLC1A1 mRNA CTD PMID:12873733 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression EXP Haloperidol results in decreased expression of SLC1A2 mRNA CTD PMID:12873733 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP Haloperidol results in decreased expression of SLC1A3 mRNA CTD PMID:15860345 NCBI chr 2:57,860,881...57,935,363
Ensembl chr 2:57,860,834...57,935,363
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Haloperidol results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc39a7 solute carrier family 39 member 7 increases expression ISO Haloperidol results in increased expression of SLC39A7 mRNA CTD PMID:14647396 NCBI chr20:3,819,416...3,822,788
Ensembl chr20:3,819,414...3,822,778
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression
ISO
EXP
SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of SLC6A3 protein
CTD PMID:14698760, PMID:17069804 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slc6a4 solute carrier family 6 member 4 increases expression EXP Haloperidol results in increased expression of SLC6A4 CTD PMID:12007678 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
JBrowse link
G Snap25 synaptosome associated protein 25 affects response to substance
affects expression
ISO
EXP
SNAP25 gene SNP affects the susceptibility to Haloperidol
Haloperidol affects the expression of SNAP25 mRNA
CTD PMID:15823421, PMID:15860345 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Haloperidol results in increased expression of SNRPD2 mRNA CTD PMID:14647396 NCBI chr 1:80,057,140...80,059,990
Ensembl chr 1:80,056,755...80,059,996
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions
EXP Haloperidol results in increased expression of SOD1 mRNA
Haloperidol results in decreased expression of SOD1 protein
Clozapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Haloperidol results in decreased activity of and results in decreased expression of SOD1 protein; olanzapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Risperidone inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]
CTD PMID:12482469, PMID:12752374, PMID:16564057 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions
EXP Haloperidol results in decreased expression of SOD2 mRNA; Haloperidol results in decreased expression of SOD2 protein
Haloperidol results in decreased activity of and results in decreased expression of SOD2 protein
CTD PMID:12482469, PMID:15860345, PMID:16564057 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Haloperidol results in increased expression of SOD3 mRNA CTD PMID:15860345 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Haloperidol results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Strn4 striatin 4 increases expression ISO Haloperidol results in increased expression of STRN4 mRNA CTD PMID:14647396 NCBI chr 1:78,739,930...78,765,696
Ensembl chr 1:78,735,678...78,765,692
JBrowse link
G Stx1a syntaxin 1A increases expression EXP Haloperidol results in increased expression of STX1A mRNA CTD PMID:15860345 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Stx1b syntaxin 1B affects expression EXP Haloperidol affects the expression of STX1B mRNA CTD PMID:15860345 NCBI chr 1:199,251,842...199,270,465
Ensembl chr 1:199,251,844...199,270,627
JBrowse link
G Stx4 syntaxin 4 increases expression EXP Haloperidol results in increased expression of STX4 mRNA CTD PMID:15860345 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Stx5 syntaxin 5 decreases expression EXP Haloperidol results in decreased expression of STX5 mRNA CTD PMID:15860345 NCBI chr 1:224,939,497...224,955,658
Ensembl chr 1:224,939,497...224,955,657
JBrowse link
G Stx7 syntaxin 7 decreases expression EXP Haloperidol results in decreased expression of STX7 mRNA CTD PMID:15860345 NCBI chr 1:22,241,655...22,281,850
Ensembl chr 1:22,241,661...22,281,788
JBrowse link
G Stx8 syntaxin 8 affects expression EXP Haloperidol affects the expression of STX8 mRNA CTD PMID:15860345 NCBI chr10:54,512,922...54,753,302
Ensembl chr10:54,512,983...54,753,302
JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component increases expression EXP Haloperidol results in increased expression of SUPT3H mRNA CTD PMID:16715494 NCBI chr 9:18,249,565...18,604,814
Ensembl chr 9:18,319,246...18,371,856
JBrowse link
G Syn2 synapsin II increases expression EXP Haloperidol results in increased expression of SYN2 mRNA CTD PMID:15860345 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Sypl1 synaptophysin-like 1 decreases expression ISO Haloperidol results in decreased expression of SYPL mRNA CTD PMID:18797397 NCBI chr 6:52,265,920...52,286,037
Ensembl chr 6:52,265,930...52,285,029
JBrowse link
G Syt11 synaptotagmin 11 increases expression EXP Haloperidol results in increased expression of SYT11 mRNA CTD PMID:15860345 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt3 synaptotagmin 3 decreases expression EXP Haloperidol results in decreased expression of SYT3 mRNA CTD PMID:15860345 NCBI chr 1:100,379,236...100,407,862
Ensembl chr 1:100,379,186...100,408,083
JBrowse link
G Syt4 synaptotagmin 4 affects expression EXP Haloperidol affects the expression of SYT4 mRNA CTD PMID:15860345 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression EXP Haloperidol results in increased expression of TAC1 mRNA CTD PMID:10974607 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tagln transgelin decreases expression ISO Haloperidol results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member decreases expression EXP Haloperidol results in decreased expression of TAP1 mRNA CTD PMID:16452686 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression ISO Haloperidol results in increased expression of TATDN1 mRNA CTD PMID:14647396 NCBI chr 7:98,782,164...98,813,001
Ensembl chr 7:98,782,178...98,804,499
JBrowse link
G Tf transferrin decreases expression ISO Haloperidol results in decreased expression of TRF mRNA CTD PMID:17177202 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Th tyrosine hydroxylase increases expression EXP Haloperidol results in increased expression of TH protein CTD PMID:17028028 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thra thyroid hormone receptor alpha decreases expression
increases expression
EXP Haloperidol results in decreased expression of THRA mRNA alternative form
Haloperidol results in increased expression of THRA mRNA alternative form
CTD PMID:11564422 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Haloperidol affects the reaction [Phencyclidine affects the expression of TNF mRNA]
Haloperidol results in increased expression of TNF protein
CTD PMID:16478754, PMID:18554768, PMID:18590723 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnik TRAF2 and NCK interacting kinase decreases expression ISO Haloperidol results in decreased expression of TNIK mRNA CTD PMID:14647396 NCBI chr 2:113,984,599...114,391,805
Ensembl chr 2:113,984,646...114,384,894
JBrowse link
G Tor1a torsin family 1, member A affects response to substance ISO TOR1A gene mutant form affects the susceptibility to Haloperidol CTD PMID:20227500 NCBI chr 3:9,800,322...9,807,318
Ensembl chr 3:9,800,322...9,807,328
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Haloperidol results in increased expression of TP53 mRNA; Haloperidol results in increased expression of TP53 protein CTD PMID:16462815 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Haloperidol results in increased expression of TPI1 mRNA CTD PMID:15860345 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Trim2 tripartite motif-containing 2 decreases expression ISO Haloperidol results in decreased expression of TRIM2 mRNA CTD PMID:14647396 NCBI chr 2:183,145,096...183,223,819
Ensembl chr 2:183,145,089...183,213,228
JBrowse link
G Trim23 tripartite motif-containing 23 decreases expression EXP Haloperidol results in decreased expression of TRIM23 mRNA CTD PMID:15860345 NCBI chr 2:34,255,300...34,288,140
Ensembl chr 2:34,255,305...34,288,139
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression ISO Haloperidol results in increased expression of UBA52 mRNA CTD PMID:14647396 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 increases expression ISO Haloperidol results in increased expression of UBE2R2 mRNA CTD PMID:14647396 NCBI chr 5:57,472,315...57,530,973
Ensembl chr 5:57,472,315...57,530,987
JBrowse link
G Ugt8 UDP glycosyltransferase 8 decreases expression ISO Haloperidol results in decreased expression of UGT8A mRNA CTD PMID:17177202 NCBI chr 2:229,644,373...229,718,678
Ensembl chr 2:229,644,382...229,718,659
JBrowse link
G Unc13a unc-13 homolog A decreases expression EXP Haloperidol results in decreased expression of UNC13A mRNA CTD PMID:15860345 NCBI chr16:20,056,398...20,103,951
Ensembl chr16:20,056,765...20,097,287
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI increases expression ISO Haloperidol results in increased expression of UQCR11 mRNA CTD PMID:14647396 NCBI chr 7:12,171,146...12,175,838
Ensembl chr 7:12,171,185...12,175,835
JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression
increases expression
EXP Haloperidol results in decreased expression of VAMP1 mRNA
Haloperidol results in increased expression of VAMP1 mRNA
CTD PMID:15860345 NCBI chr 4:157,726,941...157,733,644
Ensembl chr 4:157,726,941...157,733,643
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression
increases expression
EXP Haloperidol results in decreased expression of VAMP2 mRNA
Haloperidol results in increased expression of VAMP2 mRNA
CTD PMID:15860345 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression ISO Haloperidol results in decreased expression of VIPR2 mRNA CTD PMID:27900577 NCBI chr 6:143,932,960...144,009,476
Ensembl chr 6:143,938,040...144,008,072
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression EXP Haloperidol results in increased expression of VLDLR protein CTD PMID:19359144 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Haloperidol results in decreased expression of VSNL1 mRNA CTD PMID:12437575 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023
JBrowse link
G Wbp1l WW domain binding protein 1-like decreases expression ISO Haloperidol results in decreased expression of WBP1L mRNA CTD PMID:14647396 NCBI chr 1:266,358,728...266,415,296
Ensembl chr 1:266,358,728...266,415,296
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Haloperidol results in increased expression of WIPI1 mRNA CTD PMID:17175557 NCBI chr10:97,859,730...97,896,949
Ensembl chr10:97,859,727...97,896,525
JBrowse link
mesoridazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Mesoridazine results in decreased activity of KCNH2 protein CTD PMID:17042915 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
perazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases oxidation ISO FMO3 protein results in increased oxidation of Perazine CTD PMID:11026737 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
periciazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO periciazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO periciazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
perphenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D multiple interactions ISO Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
Perphenazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression EXP Perphenazine results in decreased expression of FSHB protein CTD PMID:6770916 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Perphenazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Perphenazine results in decreased activity of KCNH2 protein
CTD PMID:21158687, PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP Perphenazine results in decreased expression of LHB protein CTD PMID:6770916 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Prl prolactin increases expression ISO
EXP
Perphenazine results in increased expression of PRL protein CTD PMID:6770916, PMID:7262630, PMID:17335319 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Perphenazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Perphenazine results in increased expression of TNNI3 protein CTD PMID:14742781 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
pimozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Pimozide results in decreased expression of BCL2 mRNA CTD PMID:12130671 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP istradefylline inhibits the reaction [Pimozide results in increased expression of FOS protein]; Tropicamide promotes the reaction [Pimozide results in increased expression of FOS protein] CTD PMID:19467297 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 multiple interactions ISO Pimozide inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 2:209,920,590...209,932,665
Ensembl chr 2:209,920,590...209,932,665
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
ISO Pimozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Pimozide results in decreased activity of KCNH2 protein
CTD PMID:15671647, PMID:19583963, PMID:21158687, PMID:24052561 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Pimozide results in decreased secretion of and results in decreased glycosylation of LHB protein CTD PMID:3896764 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Prl prolactin increases expression ISO Pimozide results in increased expression of PRL protein CTD PMID:8915564 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
prochlorperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO Prochlorperazine results in increased activity of ACHE protein CTD PMID:29614332 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Prochlorperazine binds to and results in increased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Tfeb transcription factor EB affects localization ISO Prochlorperazine affects the localization of TFEB protein CTD PMID:28366621 NCBI chr 9:15,208,141...15,264,101
Ensembl chr 9:15,207,822...15,214,596
JBrowse link
promazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO Promazine results in decreased activity of BCHE protein CTD PMID:236606 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Promazine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Promazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Promazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
reserpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Reserpine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Reserpine results in decreased activity of ABCB11 protein
CTD PMID:20829430, PMID:23956101, PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
decreases activity
ISO Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]; Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]
Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Reserpine results in increased expression of ABCB1 mRNA; Reserpine results in increased expression of ABCB1 protein
Reserpine results in decreased activity of ABCB1 protein
CTD PMID:7476894, PMID:8632764, PMID:10617675, PMID:12235267, PMID:19528478 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of Irinotecan] CTD PMID:12869632 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
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