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Accession:CHEBI:65173 term browser browse the term
Definition:A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia.
Synonyms:exact_synonym: 1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethanone
 related_synonym: 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone;   4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone;   Fanapt;   Fanapta;   Formula=C24H27FN2O4;   InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3;   InChIKey=XMXHEBAFVSFQEX-UHFFFAOYSA-N;   SMILES=COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O;   Zomaril;   iloperidona;   iloperidonum
 xref: CAS:133454-47-4;   Drug_Central:3294;   KEGG:D02666;   LINCS:LSM-5598
 xref_mesh: MESH:C081732
 xref: PMID:21289324;   PMID:21474903;   PMID:21600386;   PMID:22161738;   PMID:22217439;   PMID:22453868;   PMID:22465688;   PMID:22617084;   Reaxys:7233425;   Wikipedia:Iloperidone

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iloperidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      biological role 19704
        pharmacological role 18809
          neurotransmitter agent 16414
            serotonergic drug 3936
              serotonergic antagonist 2235
                iloperidone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    p-block element atom 19641
                      carbon group element atom 19532
                        carbon atom 19521
                          organic molecular entity 19521
                            organic molecule 19441
                              organic cyclic compound 19203
                                organic heterocyclic compound 18278
                                  organic heteropolycyclic compound 17585
                                    organic heterobicyclic compound 16255
                                      benzoxazole 112
                                        benzisoxazole 71
                                          1,2-benzoxazoles 71
                                            iloperidone 1
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