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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
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Accession:CHEBI:65056 term browser browse the term
Definition:An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11).
Synonyms:related_synonym: D-fructose 1,6-diphosphatase inhibitor;   D-fructose 1,6-diphosphatase inhibitors;   D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor;   D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors;   D-fructose-1,6-bisphosphate phosphatase inhibitor;   D-fructose-1,6-bisphosphate phosphatase inhibitors;   EC 3.1.3.11 (fructose-bisphosphatase) inhibitors;   EC 3.1.3.11 inhibitor;   EC 3.1.3.11 inhibitors;   FBPase inhibitor;   FBPase inhibitors;   fructose 1,6-bisphosphatase inhibitor;   fructose 1,6-bisphosphatase inhibitors;   fructose 1,6-bisphosphate 1-phosphatase inhibitor;   fructose 1,6-bisphosphate 1-phosphatase inhibitors;   fructose 1,6-bisphosphate phosphatase inhibitor;   fructose 1,6-bisphosphate phosphatase inhibitors;   fructose 1,6-diphosphatase inhibitor;   fructose 1,6-diphosphatase inhibitors;   fructose 1,6-diphosphate phosphatase inhibitor;   fructose 1,6-diphosphate phosphatase inhibitors;   fructose bisphosphate phosphatase inhibitor;   fructose bisphosphate phosphatase inhibitors;   fructose diphosphatase inhibitor;   fructose diphosphatase inhibitors;   fructose diphosphate phosphatase inhibitor;   fructose diphosphate phosphatase inhibitors;   fructose-bisphosphatase inhibitor;   fructose-bisphosphatase inhibitors;   hexose bisphosphatase inhibitor;   hexose bisphosphatase inhibitors;   hexose diphosphatase inhibitor
 xref: Wikipedia:Fructose_1\,6-bisphosphatase



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adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP-binding cassette, sub-family C member 9 multiple interactions EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 6:142,533,592...142,648,472
Ensembl chr 6:142,533,588...142,648,041
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions ISO [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 increases abundance EXP ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr14:32,235,248...32,302,947
Ensembl chr14:32,235,478...32,302,947
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188
JBrowse link
G Nudt10 nudix hydrolase 10 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:6,080,750...6,085,321
Ensembl chr  X:6,080,750...6,085,069
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888
JBrowse link
G Trp73 transformation related protein 73 affects abundance EXP TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
JBrowse link

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  CHEBI ontology 22188
    role 22173
      biological role 22172
        biochemical role 21436
          enzyme inhibitor 19915
            EC 3.* (hydrolase) inhibitor 19258
              EC 3.1.* (ester hydrolase) inhibitor 15196
                EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor 10501
                  EC 3.1.3.11 (fructose-bisphosphatase) inhibitor 9
                    adenosine 5'-monophosphate + 9
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