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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.1.3.11 (fructose-bisphosphatase) inhibitor
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Accession:CHEBI:65056 term browser browse the term
Definition:An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of fructose-bisphosphatase (EC 3.1.3.11).
Synonyms:related_synonym: D-fructose 1,6-diphosphatase inhibitor;   D-fructose 1,6-diphosphatase inhibitors;   D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitor;   D-fructose-1,6-bisphosphate 1-phosphohydrolase inhibitors;   D-fructose-1,6-bisphosphate phosphatase inhibitor;   D-fructose-1,6-bisphosphate phosphatase inhibitors;   EC 3.1.3.11 (fructose-bisphosphatase) inhibitors;   EC 3.1.3.11 inhibitor;   EC 3.1.3.11 inhibitors;   FBPase inhibitor;   FBPase inhibitors;   fructose 1,6-bisphosphatase inhibitor;   fructose 1,6-bisphosphatase inhibitors;   fructose 1,6-bisphosphate 1-phosphatase inhibitor;   fructose 1,6-bisphosphate 1-phosphatase inhibitors;   fructose 1,6-bisphosphate phosphatase inhibitor;   fructose 1,6-bisphosphate phosphatase inhibitors;   fructose 1,6-diphosphatase inhibitor;   fructose 1,6-diphosphatase inhibitors;   fructose 1,6-diphosphate phosphatase inhibitor;   fructose 1,6-diphosphate phosphatase inhibitors;   fructose bisphosphate phosphatase inhibitor;   fructose bisphosphate phosphatase inhibitors;   fructose diphosphatase inhibitor;   fructose diphosphatase inhibitors;   fructose diphosphate phosphatase inhibitor;   fructose diphosphate phosphatase inhibitors;   fructose-bisphosphatase inhibitor;   fructose-bisphosphatase inhibitors;   hexose bisphosphatase inhibitor;   hexose bisphosphatase inhibitors;   hexose diphosphatase inhibitor
 xref: Wikipedia:Fructose_1\,6-bisphosphatase


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adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases abundance ISO ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Nudt11 nudix hydrolase 11 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:17,171,510...17,215,108
Ensembl chr  X:17,540,458...17,540,952
Ensembl chr  X:17,540,458...17,540,952
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Tp73 tumor protein p73 affects abundance ISO TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      biological role 19804
        biochemical role 19339
          enzyme inhibitor 18208
            EC 3.* (hydrolase) inhibitor 17702
              EC 3.1.* (ester hydrolase) inhibitor 12895
                EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor 9982
                  EC 3.1.3.11 (fructose-bisphosphatase) inhibitor 7
                    adenosine 5'-monophosphate + 7
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