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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor
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Accession:CHEBI:64964 term browser browse the term
Definition:A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34).
Synonyms:related_synonym: 5-LOX inhibitor;   5-LOX inhibitors;   5-lipoxygenase inhibitor;   5-lipoxygenase inhibitors;   5delta-lipoxygenase inhibitor;   5delta-lipoxygenase inhibitors;   C-5-lipoxygenase inhibitor;   C-5-lipoxygenase inhibitors;   EC 1.13.11.34 inhibitor;   EC 1.13.11.34 inhibitors;   LTA synthase inhibitor;   LTA synthase inhibitors;   arachidonate 5-lipoxygenase (EC 1.13.11.34) inhibitors;   arachidonate 5-lipoxygenase inhibitor;   arachidonate 5-lipoxygenase inhibitors;   arachidonic 5-lipoxygenase inhibitor;   arachidonic 5-lipoxygenase inhibitors;   arachidonic acid 5-lipoxygenase inhibitor;   arachidonic acid 5-lipoxygenase inhibitors;   delta(5)-lipoxygenase inhibitor;   delta(5)-lipoxygenase inhibitors;   leukotriene A4 synthase inhibitors;   leukotriene-A4 synthase inhibitor


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3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd2 ATP binding cassette subfamily D member 2 increases expression ISO MK-886 results in increased expression of ABCD2 mRNA CTD PMID:18292206 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase multiple interactions EXP MK-886 inhibits the reaction [pirinixic acid results in decreased expression of ACMSD mRNA] CTD PMID:18320257 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions
increases expression
EXP
ISO
MK-886 inhibits the reaction [pirinixic acid results in increased expression of ACOX1 mRNA]
MK-886 results in increased expression of ACOX1 mRNA
CTD PMID:18292206, PMID:18320257 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO MK-886 inhibits the reaction [Arsenic Trioxide results in increased expression of ACTA2 protein] CTD PMID:30677399 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases activity
ISO
EXP
MK-886 inhibits the reaction [ALOX5 protein results in increased metabolism of Hydroxyeicosatetraenoic Acids metabolite]; MK-886 inhibits the reaction [Nicotine results in increased expression of ALOX5 protein]
MK-886 results in decreased activity of ALOX5 protein
EPHX2 gene mutant form promotes the reaction [MK-886 inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 protein]]; MK-886 inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 protein]
CTD PMID:9445378, PMID:11861792, PMID:14726295, PMID:19896470, PMID:20061081 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions
decreases activity
ISO
EXP
[MK-886 results in decreased activity of ALOX5AP protein] which results in decreased abundance of Leukotriene C4; MK-886 binds to and results in decreased activity of ALOX5AP protein; MK-886 inhibits the reaction [ALOX5AP protein results in increased susceptibility to [Histamine results in increased abundance of Leukotriene B4]] CTD PMID:7990266, PMID:8058773, PMID:8666909, PMID:9113110, PMID:9609743, PMID:9850156, PMID:12629151 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
decreases expression
ISO MK-886 inhibits the reaction [TNF protein results in decreased expression of APOA1 mRNA]
MK-886 results in decreased expression of APOA1 protein
CTD PMID:19883121 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in decreased expression of BAX protein] CTD PMID:20061081 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of BCL2 protein] CTD PMID:20061081 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in decreased expression of CASP3 protein] CTD PMID:20061081 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein CTD PMID:22135674 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of CCND1 mRNA]; MK-886 inhibits the reaction [Nicotine results in increased expression of CCND1 protein] CTD PMID:20061081 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of CCNE1 protein] CTD PMID:20061081 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [MK-886 binds to and results in decreased activity of PPARA protein] inhibits the reaction [perfluorooctanoic acid results in decreased expression of CDH1 protein]; MK-886 inhibits the reaction [Nicotine results in decreased expression of CDH1 mRNA] CTD PMID:20061081, PMID:23978332 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [MK-886 binds to and results in decreased activity of PPARA protein] inhibits the reaction [perfluorooctanoic acid results in decreased expression of CTNNB1 protein] CTD PMID:23978332 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO MK-886 promotes the reaction [Dronabinol results in increased expression of CYP1A1 mRNA] CTD PMID:25291031 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of E2F1 protein] CTD PMID:20061081 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein CTD PMID:22135674 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO EPHX2 gene mutant form promotes the reaction [[Lipopolysaccharides co-treated with MK-886] results in decreased abundance of 11,12-dihydroxyeicosatrienoic acid]; EPHX2 gene mutant form promotes the reaction [[Lipopolysaccharides co-treated with MK-886] results in decreased abundance of 14,15-dihydroxyeicosatrienoic acid]; EPHX2 gene mutant form promotes the reaction [MK-886 inhibits the reaction [Lipopolysaccharides results in increased abundance of 5-hydroxy-6,8,11,14-eicosatetraenoic acid]]; EPHX2 gene mutant form promotes the reaction [MK-886 inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 protein]]; MK-886 promotes the reaction [EPHX2 gene mutant form results in decreased susceptibility to Lipopolysaccharides] CTD PMID:19896470 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO MK-886 inhibits the reaction [3-((O-6-deoxymannopyranosyl-1-2-O-(xylopyranosyl-1-3)arabinopyranosyl)oxy)-21-glucopyranosyloxy-20-hydroxydammar-24-en-19-al inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]]; MK-886 inhibits the reaction [pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]] CTD PMID:17141290 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fa2h fatty acid 2-hydroxylase multiple interactions ISO MK-886 inhibits the reaction [Dronabinol results in increased expression of FA2H mRNA]; MK-886 promotes the reaction [Dronabinol results in increased expression of FA2H mRNA] CTD PMID:23535410, PMID:25291031 NCBI chr19:43,545,380...43,596,788
Ensembl chr19:43,545,378...43,596,801
JBrowse link
G Il10 interleukin 10 multiple interactions ISO MK-886 inhibits the reaction [Zymosan results in increased secretion of IL10 protein] CTD PMID:16313356 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il6 interleukin 6 multiple interactions ISO MK-886 promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:19896470 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO MK-886 inhibits the reaction [mangiferin results in increased activity of LPL protein]; MK-886 inhibits the reaction [mangiferin results in increased expression of LPL mRNA]; MK-886 inhibits the reaction [Plant Extracts results in increased activity of LPL protein]; MK-886 inhibits the reaction [Plant Extracts results in increased expression of LPL mRNA] CTD PMID:15975614 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Ltb4r leukotriene B4 receptor multiple interactions EXP MK-886 binds to and results in decreased activity of LTB4R protein; MK-886 inhibits the reaction [LTB4R protein results in increased susceptibility to Formaldehyde] CTD PMID:19835937 NCBI chr15:34,449,299...34,453,352
Ensembl chr15:34,452,116...34,453,171
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO MK-886 inhibits the reaction [Arsenic Trioxide results in increased cleavage of MAP1LC3B protein] CTD PMID:30677399 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of MMP7 mRNA] CTD PMID:20061081 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of MMP9 mRNA]
MK-886 inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of MMP9 protein]
CTD PMID:19837106, PMID:20061081 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO [fulvestrant co-treated with MK-886] inhibits the reaction [resveratrol results in increased expression of NOS3 mRNA] CTD PMID:21791144 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions ISO MK-886 inhibits the reaction [Bezafibrate results in increased expression of PDK4 mRNA]; MK-886 inhibits the reaction [Bezafibrate results in increased expression of PDK4 protein] CTD PMID:19683050 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pla2g4a phospholipase A2 group IVA multiple interactions ISO MK-886 inhibits the reaction [Histamine results in increased expression of PLA2G4A mRNA] CTD PMID:9609743 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of PLAU mRNA] CTD PMID:20061081 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of PLAUR mRNA] CTD PMID:20061081 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Poli DNA polymerase iota decreases activity ISO MK-886 results in decreased activity of POLI protein CTD PMID:23305233 NCBI chr18:65,749,107...65,768,805
Ensembl chr18:65,748,908...65,768,781
JBrowse link
G Polk DNA polymerase kappa decreases activity ISO MK-886 results in decreased activity of POLK protein CTD PMID:23305233 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906
JBrowse link
G Polm DNA polymerase mu decreases activity ISO MK-886 results in decreased activity of POLM protein CTD PMID:23305233 NCBI chr14:86,069,378...86,079,327
Ensembl chr14:86,069,016...86,078,954
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
ISO
EXP
[MK-886 binds to and results in decreased activity of PPARA protein] inhibits the reaction [perfluorooctanoic acid results in decreased expression of CDH1 protein]; [MK-886 binds to and results in decreased activity of PPARA protein] inhibits the reaction [perfluorooctanoic acid results in decreased expression of CTNNB1 protein]; [MK-886 binds to and results in decreased activity of PPARA protein] which results in decreased susceptibility to perfluorooctanoic acid; MK-886 binds to and results in decreased activity of PPARA protein; MK-886 inhibits the reaction [Arsenic Trioxide results in increased expression of PPARA protein]; MK-886 inhibits the reaction [Bezafibrate results in increased expression of PPARA mRNA]; MK-886 inhibits the reaction [mangiferin results in increased activity of PPARA protein]; MK-886 inhibits the reaction [perfluorooctane sulfonic acid results in increased activity of PPARA protein]; MK-886 inhibits the reaction [perfluorooctanoic acid results in increased activity of PPARA protein]; MK-886 inhibits the reaction [Plant Extracts results in increased activity of PPARA protein]; MK-886 promotes the reaction [Dronabinol results in increased expression of PPARA mRNA]
[MK-886 binds to and results in decreased activity of PPARA protein] which results in decreased susceptibility to palmidrol analog; MK-886 binds to and results in decreased activity of PPARA protein
MK-886 binds to and results in decreased activity of PPARA protein; MK-886 inhibits the reaction [perfluorooctane sulfonic acid results in increased activity of PPARA protein]; MK-886 inhibits the reaction [perfluorooctanoic acid results in increased activity of PPARA protein]
MK-886 results in increased expression of PPARA mRNA
CTD PMID:15899809, PMID:15975614, PMID:17047030, PMID:17558434, PMID:18292206, PMID:18320257, PMID:19403796, PMID:19683050, PMID:19883121, PMID:23978332, PMID:25291031, PMID:30677399 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
increases activity
affects localization
ISO [Indomethacin co-treated with MK-886] affects the localization of PPARG protein; Indomethacin promotes the reaction [MK-886 results in increased activity of PPARG protein]
MK-886 results in increased expression of PPARG mRNA
MK-886 affects the localization of PPARG protein
CTD PMID:15899809 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptges prostaglandin E synthase decreases activity ISO MK-886 results in decreased activity of PTGES protein CTD PMID:20933508, PMID:25451575 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of RB1 protein modified form] CTD PMID:20061081 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO MK-886 inhibits the reaction [pirinixic acid results in decreased phosphorylation of RELA protein] CTD PMID:17371993 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rxra retinoid X receptor alpha increases expression
multiple interactions
ISO MK-886 results in increased expression of RXRA mRNA
[MK-886 co-treated with Indomethacin] results in increased expression of RXRA mRNA
CTD PMID:15899809 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G S100b S100 calcium binding protein B multiple interactions EXP MK-886 inhibits the reaction [pirinixic acid affects the expression of S100B protein] CTD PMID:16863991 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Selp selectin P multiple interactions ISO MK-886 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of SELP protein] CTD PMID:11116075 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO MK-886 promotes the reaction [SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate]; MK-886 promotes the reaction [SOD2 gene mutant form results in increased abundance of Lactic Acid] CTD PMID:25362851 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tfdp1 transcription factor Dp-1 multiple interactions ISO MK-886 inhibits the reaction [Nicotine results in increased expression of TFDP1 protein] CTD PMID:20061081 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Ovalbumin co-treated with MK-886] results in increased expression of TNF protein; MK-886 inhibits the reaction [TNF protein results in decreased expression of APOA1 mRNA]; monascin inhibits the reaction [[Ovalbumin co-treated with MK-886] results in increased expression of TNF protein] CTD PMID:19883121, PMID:22381257 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP MK-886 inhibits the reaction [pirinixic acid results in increased expression of UCP2 mRNA]; MK-886 inhibits the reaction [pirinixic acid results in increased expression of UCP2 protein] CTD PMID:16782780 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
acteoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions
decreases localization
ISO acteoside promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased localization of AHR protein]
acteoside results in decreased localization of AHR protein
CTD PMID:21756928 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases localization ISO acteoside results in increased localization of ARNT protein CTD PMID:21756928 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
decreases secretion
ISO acteoside results in decreased expression of CCL2 mRNA
acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
acteoside results in decreased secretion of CCL2 protein
CTD PMID:21756928, PMID:21967610 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO acteoside results in decreased expression of CCND1 protein CTD PMID:17634406 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO acteoside results in decreased expression of CCND2 protein CTD PMID:17634406 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO acteoside results in decreased expression of CCND3 protein CTD PMID:17634406 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO acteoside results in decreased expression of CCNE1 protein CTD PMID:17634406 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO acteoside results in decreased expression of and results in decreased activity of CDK2 protein CTD PMID:17634406 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity
multiple interactions
ISO acteoside results in decreased activity of CDK4 protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]
CTD PMID:17634406 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]; acteoside results in decreased expression of and results in decreased activity of CDK6 protein CTD PMID:17634406 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO acteoside results in increased expression of CDKN1A mRNA; acteoside results in increased expression of CDKN1A protein
acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein]
CTD PMID:17634406 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO acteoside results in increased expression of CDKN1B mRNA; acteoside results in increased expression of CDKN1B protein
acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein]; acteoside promotes the reaction [CDKN1B protein binds to CDK6 protein]
CTD PMID:17634406 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases secretion
decreases expression
multiple interactions
ISO acteoside results in decreased secretion of CXCL10 protein
acteoside results in decreased expression of CXCL10 mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [PD168393 results in increased secretion of CXCL10 protein]; acteoside promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein]
CTD PMID:21756928, PMID:21967610 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO acteoside results in increased expression of CYP1A1 mRNA CTD PMID:21756928 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein] CTD PMID:14672760 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein] CTD PMID:17634406 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation
multiple interactions
ISO acteoside results in decreased phosphorylation of EGFR protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein]
CTD PMID:21756928, PMID:21967610 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO acteoside results in decreased expression of ICAM1 mRNA CTD PMID:21371465 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
ISO acteoside results in decreased expression of IFNG mRNA
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]
CTD PMID:21371465, PMID:21756928 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]
acteoside results in decreased expression of IL6 mRNA
CTD PMID:21756928 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO acteoside inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] CTD PMID:16393473 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
decreases phosphorylation
ISO acteoside results in increased phosphorylation of MAPK1 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]
acteoside results in decreased phosphorylation of MAPK1 protein
CTD PMID:21756928, PMID:23527233 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation
ISO acteoside results in decreased phosphorylation of MAPK3 protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]
acteoside results in increased phosphorylation of MAPK3 protein
CTD PMID:21756928, PMID:23527233 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nox1 NADPH oxidase 1 decreases activity ISO acteoside results in decreased activity of NOX1 protein CTD PMID:16393473 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO acteoside binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [acteoside co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTGS2 mRNA CTD PMID:21756928 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation
multiple interactions
ISO acteoside results in decreased phosphorylation of RB1 protein
[acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein]
CTD PMID:17634406 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
decreases phosphorylation
ISO acteoside results in increased phosphorylation of RELA protein
acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein]
acteoside results in decreased phosphorylation of RELA protein
CTD PMID:21756928, PMID:23527233 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation ISO acteoside results in increased phosphorylation of SMAD2 protein CTD PMID:17634406 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 increases phosphorylation ISO acteoside results in increased phosphorylation of SMAD3 protein CTD PMID:17634406 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO acteoside results in decreased expression of SOD2 mRNA CTD PMID:21371465 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO [acteoside co-treated with TGFA protein] results in increased expression of CXCL8 mRNA; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein modified form]; acteoside promotes the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21756928, PMID:21967610 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO acteoside results in increased expression of TGFB1 mRNA CTD PMID:17634406 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein] CTD PMID:21756928 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO acteoside results in decreased expression of VCAM1 mRNA CTD PMID:21371465 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
azelastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
ISO azelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; azelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
azelastine results in decreased activity of ABCB1 protein
CTD PMID:11231118 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO azelastine results in decreased expression of COL1A1 mRNA CTD PMID:8919039 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO azelastine results in decreased expression of COL3A1 mRNA CTD PMID:8919039 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression ISO azelastine results in decreased expression of COL6A1 mRNA CTD PMID:8919039 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Hrh1 histamine receptor H 1 affects binding ISO azelastine binds to HRH1 protein CTD PMID:2540229 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO azelastine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO azelastine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
benoxaprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin decreases response to substance ISO ALB protein results in decreased susceptibility to benoxaprofen CTD PMID:6699424 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type decreases activity EXP benoxaprofen results in decreased activity of ALOX12 protein CTD PMID:3928952 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases activity
ISO
EXP
[benoxaprofen results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4; [benoxaprofen results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5,8,11,13-eicosatetraenoic acid CTD PMID:2724698, PMID:2849922, PMID:3020588, PMID:3928952 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP benoxaprofen results in increased expression of CYP1A1 protein CTD PMID:2069584 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP benoxaprofen results in increased expression of CYP1A2 protein CTD PMID:2069584 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP benoxaprofen results in increased expression of CYP4A1 protein CTD PMID:2069584 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP benoxaprofen results in increased expression of EHHADH protein CTD PMID:2069584 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Gusb glucuronidase, beta increases secretion ISO benoxaprofen results in increased secretion of GUSB protein CTD PMID:6737371 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP benoxaprofen inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; benoxaprofen inhibits the reaction [LHB protein results in increased abundance of Testosterone] CTD PMID:6430271 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 affects response to substance ISO UGT1A3 affects the susceptibility to benoxaprofen CTD PMID:17880178 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects response to substance ISO UGT1A9 affects the susceptibility to benoxaprofen CTD PMID:17880178 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 affects response to substance
increases glucuronidation
ISO UGT2B7 affects the susceptibility to benoxaprofen
UGT2B7 protein alternative form results in increased glucuronidation of benoxaprofen
CTD PMID:8423545, PMID:17880178 NCBI chr14:22,597,103...22,619,968 JBrowse link
chlorogenic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC1 protein] CTD PMID:25043994 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein] CTD PMID:25043994 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Ache acetylcholinesterase decreases activity ISO Chlorogenic Acid results in decreased activity of ACHE protein CTD PMID:20854806 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acly ATP citrate lyase increases expression ISO Chlorogenic Acid results in increased expression of ACLY mRNA CTD PMID:20706672 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:23146752 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Alb albumin multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of ALB protein]
Chlorogenic Acid affects the reaction [2,2'-azobis(2-amidinopropane) results in increased degradation of ALB protein]
CTD PMID:11322927, PMID:23146752 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Chlorogenic Acid results in increased expression of AQP1 mRNA CTD PMID:20706672 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Chlorogenic Acid results in increased expression of AQP3 mRNA CTD PMID:20706672 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Ar androgen receptor decreases expression ISO Chlorogenic Acid results in decreased expression of AR mRNA CTD PMID:20706672 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions EXP Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAMBI mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of BAMBI protein] CTD PMID:23146752 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
Chlorogenic Acid inhibits the reaction [aluminum chloride results in increased expression of BAX protein]; Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of BAX protein]
Chlorogenic Acid inhibits the reaction [Methotrexate results in increased expression of BAX protein]
CTD PMID:25043994, PMID:28479099, PMID:28623112 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]
Chlorogenic Acid inhibits the reaction [aluminum chloride results in decreased expression of BCL2 protein]
CTD PMID:28479099, PMID:28623112 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
Chlorogenic Acid inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
Chlorogenic Acid inhibits the reaction [Methotrexate results in increased activity of CASP3 protein]
CTD PMID:25043994, PMID:28479099 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Chlorogenic Acid inhibits the reaction [aluminum chloride results in increased expression of CASP8 protein] CTD PMID:28623112 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Chlorogenic Acid inhibits the reaction [Methotrexate results in increased activity of CASP9 protein] CTD PMID:28479099 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in decreased activity of CAT protein]
Chlorogenic Acid inhibits the reaction [aluminum chloride results in decreased activity of CAT protein]
CTD PMID:28479099, PMID:28623112, PMID:31390532 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of CCL2 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of CCL2 protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:26079055, PMID:31306686 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CCND1 protein] CTD PMID:25043994 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO Chlorogenic Acid results in increased expression of CD44 mRNA CTD PMID:20706672 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Chlorogenic Acid results in increased expression of CDH1 mRNA CTD PMID:20706672 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO
EXP
Chlorogenic Acid results in increased expression of COL1A1 mRNA
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]
CTD PMID:20706672, PMID:23146752 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Cs citrate synthase increases activity ISO Chlorogenic Acid results in increased activity of CS protein CTD PMID:31306686 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of CXCL1 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of CXCL1 protein] CTD PMID:26079055 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cygb cytoglobin decreases expression ISO Chlorogenic Acid results in decreased expression of CYGB mRNA CTD PMID:20706672 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP Chlorogenic Acid results in increased expression of CYP19A1 protein CTD PMID:29899696 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein] CTD PMID:25043994 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dsg3 desmoglein 3 decreases expression ISO Chlorogenic Acid results in decreased expression of DSG3 mRNA CTD PMID:20706672 NCBI chr18:15,652,948...15,688,605
Ensembl chr18:15,650,526...15,688,284
JBrowse link
G Egf epidermal growth factor decreases expression ISO Chlorogenic Acid results in decreased expression of EGF mRNA CTD PMID:20706672 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP Chlorogenic Acid results in decreased expression of ESR1 protein CTD PMID:29899696 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases expression EXP Chlorogenic Acid results in increased expression of ESR2 protein CTD PMID:29899696 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G F10 coagulation factor X decreases activity ISO Chlorogenic Acid results in decreased activity of F10 protein CTD PMID:27704645 NCBI chr16:81,803,169...81,822,476
Ensembl chr16:81,803,110...81,822,716
JBrowse link
G F2 coagulation factor II decreases activity ISO Chlorogenic Acid results in decreased activity of F2 protein CTD PMID:27704645 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Chlorogenic Acid results in decreased expression of FASN mRNA CTD PMID:21870829 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO Chlorogenic Acid results in decreased expression of FBN1 mRNA CTD PMID:20706672 NCBI chr 3:117,569,708...117,766,160
Ensembl chr 3:117,569,697...117,766,120
JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO Chlorogenic Acid results in decreased expression of FBN2 mRNA CTD PMID:20706672 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Chlorogenic Acid results in increased expression of FGF1 mRNA CTD PMID:20706672 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression EXP Chlorogenic Acid results in increased expression of FSHR protein CTD PMID:29899696 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO Chlorogenic Acid results in increased expression of GCLC mRNA
Chlorogenic Acid promotes the reaction [Acetaminophen results in increased expression of GCLC mRNA]
CTD PMID:29136249 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Chlorogenic Acid results in increased expression of GCLM mRNA CTD PMID:29136249 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of GPT protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased activity of GPT protein]
Chlorogenic Acid inhibits the reaction [aluminum chloride results in increased activity of GPT protein]
CTD PMID:28479099, PMID:28623112, PMID:31390532 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grn granulin precursor increases expression ISO Chlorogenic Acid results in increased expression of GRN mRNA CTD PMID:20706672 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Chlorogenic Acid inhibits the reaction [Methotrexate results in decreased activity of GSR protein] CTD PMID:28479099 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases activity ISO Chlorogenic Acid results in increased activity of GSTA1 protein CTD PMID:15944151 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Has1 hyaluronan synthase 1 increases expression ISO Chlorogenic Acid results in increased expression of HAS1 mRNA CTD PMID:20706672 NCBI chr 1:59,720,612...59,732,409
Ensembl chr 1:59,720,612...59,732,409
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Chlorogenic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases expression
EXP
ISO
[tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]
Chlorogenic Acid results in decreased expression of HMGCR mRNA
CTD PMID:20696151, PMID:21870829 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of HMOX1 protein]
Chlorogenic Acid results in increased expression of HMOX1 mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein]
CTD PMID:25043994, PMID:29136249 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO Chlorogenic Acid results in increased expression of HSPB1 mRNA CTD PMID:20706672 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Chlorogenic Acid results in decreased expression of IL1A mRNA CTD PMID:20706672 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B mRNA]
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of IL1B protein]
CTD PMID:23146752, PMID:24709313, PMID:26079055 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Chlorogenic Acid results in increased expression of IL6 mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of IL6 protein]
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL6 protein]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 mRNA]
CTD PMID:21870829, PMID:23146752, PMID:26079055, PMID:31390532 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression
multiple interactions
EXP Chlorogenic Acid results in decreased expression of ITGB2 protein
Chlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of ITGB2 protein]
CTD PMID:21414398 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein] CTD PMID:15944151 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Krt5 keratin 5 increases expression ISO Chlorogenic Acid results in increased expression of KRT5 mRNA CTD PMID:20706672 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein] CTD PMID:20696151 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein] CTD PMID:20696151 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO Chlorogenic Acid results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B decreases activity ISO Chlorogenic Acid results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein] CTD PMID:15944151 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
Chlorogenic Acid promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK1 protein]
CTD PMID:15944151, PMID:29136249 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein] CTD PMID:15944151 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
Chlorogenic Acid promotes the reaction [Acetaminophen results in increased phosphorylation of MAPK3 protein]
CTD PMID:15944151, PMID:29136249 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mc1r melanocortin 1 receptor increases expression ISO Chlorogenic Acid results in increased expression of MC1R mRNA CTD PMID:20706672 NCBI chr19:56,215,420...56,219,987 JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Chlorogenic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of MPO protein] CTD PMID:26079055 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression ISO Chlorogenic Acid results in increased expression of COX1 mRNA CTD PMID:20706672 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [Chlorogenic Acid co-treated with Zymosan] results in decreased expression of COX2 protein; Chlorogenic Acid inhibits the reaction [Zymosan results in increased expression of COX2 protein] CTD PMID:30481570 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt1 metallothionein 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MT1 mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MT1 protein] CTD PMID:31390532 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of MYD88 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of MYD88 protein]
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of MYD88 protein]
CTD PMID:23146752, PMID:26079055 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases localization
multiple interactions
increases response to substance
affects localization
decreases response to substance
ISO Chlorogenic Acid results in increased localization of NFE2L2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Chlorogenic Acid co-treated with Acetaminophen] results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein]; [Chlorogenic Acid co-treated with Acetaminophen] results in increased activity of and affects the localization of NFE2L2 protein; [Chlorogenic Acid co-treated with Acetaminophen] results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein; U 0126 inhibits the reaction [[Chlorogenic Acid co-treated with Acetaminophen] results in increased phosphorylation of and affects the localization of and results in increased activity of NFE2L2 protein]
[Chlorogenic Acid co-treated with Acetaminophen] affects the localization of and results in increased activity of NFE2L2 protein
NFE2L2 results in increased susceptibility to Chlorogenic Acid
Chlorogenic Acid affects the localization of NFE2L2 protein
NFE2L2 gene mutant form results in decreased susceptibility to Chlorogenic Acid
CTD PMID:15944151, PMID:29136249 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO
EXP
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:20026373, PMID:23146752 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein] CTD PMID:20026373 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Chlorogenic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased expression of NOS2 protein]
CTD PMID:20026373, PMID:23146752, PMID:28479099, PMID:31306686 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO Chlorogenic Acid results in increased expression of NOS3 mRNA CTD PMID:20706672 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression
multiple interactions
ISO Chlorogenic Acid results in increased activity of NQO1 protein
Chlorogenic Acid results in increased expression of NQO1 mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of NQO1 mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of NQO1 protein]
CTD PMID:15944151, PMID:29136249 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ocln occludin multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of OCLN mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of OCLN protein] CTD PMID:31390532 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Chlorogenic Acid promotes the reaction [Cisplatin results in increased expression of PCNA protein] CTD PMID:25043994 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PECAM1 protein] CTD PMID:21414398 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pgr progesterone receptor increases expression
decreases expression
ISO Chlorogenic Acid results in increased expression of PGR mRNA
Chlorogenic Acid results in decreased expression of PGR mRNA
CTD PMID:20706672 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO Chlorogenic Acid results in increased expression of PIK3R1 mRNA CTD PMID:21870829 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 increases expression ISO Chlorogenic Acid results in increased expression of PLOD3 mRNA CTD PMID:20706672 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
decreases expression
ISO Chlorogenic Acid results in increased expression of PPARG mRNA
Chlorogenic Acid results in decreased expression of PPARG mRNA
CTD PMID:20706672, PMID:21870829 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha multiple interactions ISO [Chlorogenic Acid co-treated with Acetaminophen] results in decreased expression of PPP2R1A protein CTD PMID:29136249 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO [Chlorogenic Acid co-treated with Acetaminophen] results in decreased expression of PPP5C protein CTD PMID:29136249 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Methotrexate results in increased expression of PTGS2 protein]
Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]
CTD PMID:20026373, PMID:23146752, PMID:25043994, PMID:28479099, PMID:31306686 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Chlorogenic Acid results in decreased expression of RAD23A mRNA CTD PMID:20706672 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Chlorogenic Acid results in increased expression of RARA mRNA CTD PMID:20706672 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of and results in increased phosphorylation of and affects the localization of RELA protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein] CTD PMID:20026373, PMID:26079055 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Chlorogenic Acid results in decreased expression of RXRA mRNA CTD PMID:20706672 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Sell selectin L multiple interactions EXP [Chlorogenic Acid co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of SELL protein; Chlorogenic Acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in decreased expression of SELL protein] CTD PMID:21414398 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC11A2 mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC11A2 protein] CTD PMID:31390532 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in decreased expression of SLC22A2 protein] CTD PMID:25043994 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Chlorogenic Acid results in increased expression of SLC2A4 mRNA CTD PMID:21870829 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Chlorogenic Acid results in decreased expression of SOD3 mRNA CTD PMID:20706672 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in decreased expression of SQSTM1 protein] CTD PMID:29136249 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO Chlorogenic Acid results in decreased expression of SRD5A2 mRNA CTD PMID:20706672 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511
JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP Chlorogenic Acid results in increased expression of STAR protein CTD PMID:29899696 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TJP1 mRNA]; Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TJP1 protein] CTD PMID:31390532 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR3 protein] CTD PMID:26079055 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP
ISO
Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 mRNA]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TLR4 protein]
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TLR4 protein]
CTD PMID:23146752, PMID:26079055 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO
EXP
Chlorogenic Acid results in increased expression of TNF mRNA
Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; Chlorogenic Acid inhibits the reaction [Acetaminophen results in increased secretion of TNF protein]; Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Chlorogenic Acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Chlorogenic Acid inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TNF protein]; Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]
CTD PMID:21870829, PMID:23146752, PMID:25043994, PMID:26079055, PMID:31306686, PMID:31390532 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of TRP53 protein] CTD PMID:25043994 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression ISO Chlorogenic Acid results in increased expression of TPT1 mRNA CTD PMID:20706672 NCBI chr15:57,891,680...57,894,504
Ensembl chr15:57,891,680...57,894,504
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Chlorogenic Acid results in increased expression of TXN mRNA CTD PMID:20706672 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Tyr tyrosinase increases oxidation
multiple interactions
ISO TYR protein results in increased oxidation of Chlorogenic Acid
[TYR protein results in increased oxidation of Chlorogenic Acid] which results in decreased abundance of Glutathione
CTD PMID:20685355 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO Chlorogenic Acid results in decreased expression of TYRP1 mRNA CTD PMID:20706672 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Chlorogenic Acid CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Chlorogenic Acid CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
cis-caffeic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO caffeic acid results in increased phosphorylation of and results in decreased activity of ACACA protein CTD PMID:28576465 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
EXP caffeic acid inhibits the reaction [Caffeine results in decreased activity of ACHE protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of ACHE protein] CTD PMID:28465162 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of ACLY protein CTD PMID:28576465 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions
decreases activity
ISO [caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]; [caffeic acid results in decreased activity of ALOX15 protein] which results in decreased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [caffeic acid results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; caffeic acid inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of ALOX15 protein] CTD PMID:10904086, PMID:11406566, PMID:15574791 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [Aluminum results in increased expression of ALOX5 protein]; caffeic acid inhibits the reaction [Hydrogen Peroxide affects the localization of ALOX5 protein]
caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 mRNA]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of ALOX5 protein]
CTD PMID:18482095, PMID:18951527, PMID:27368151 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein modified form]; caffeic acid inhibits the reaction [aluminum chloride results in increased expression of APP protein] CTD PMID:18482095 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arg1 arginase 1 decreases activity ISO caffeic acid results in decreased activity of ARG1 protein CTD PMID:27378625 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA] CTD PMID:19442820 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
[caffeic acid results in decreased activity of ALOX15 protein] inhibits the reaction [vorinostat results in increased activity of CASP3 protein]
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of CASP3 protein]
CTD PMID:15574791, PMID:29968957 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP
ISO
caffeic acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Nickel results in decreased activity of CAT protein]
caffeic acid results in increased activity of CAT protein
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
CTD PMID:18405891, PMID:21640567, PMID:22036979, PMID:27378625 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL2 mRNA; caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:16806235, PMID:31306686 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL3 mRNA CTD PMID:16806235 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCL4 mRNA CTD PMID:16806235 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR1 mRNA CTD PMID:16806235 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR2 mRNA CTD PMID:16806235
G Ccr4 C-C motif chemokine receptor 4 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CCR4 mRNA CTD PMID:16806235 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD4 mRNA CTD PMID:16806235 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of CD68 mRNA CTD PMID:16806235 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA CTD PMID:19442820 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA] CTD PMID:19442820 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO caffeic acid inhibits the reaction [aluminum chloride results in decreased expression of CHAT protein] CTD PMID:18482095 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of caffeic acid CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP caffeic acid inhibits the reaction [Malathion results in decreased expression of CRH mRNA] CTD PMID:25404496 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA] CTD PMID:19442820 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Ctsb cathepsin B multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein] CTD PMID:20391626 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein] CTD PMID:20391626 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA] CTD PMID:19442820 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine] CTD PMID:7710944 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dap death-associated protein multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA] CTD PMID:19442820 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA] CTD PMID:19442820 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA] CTD PMID:19442820 NCBI chr 1:211,423,022...211,438,533
Ensembl chr 1:211,423,022...211,438,531
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA CTD PMID:16806235 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO caffeic acid affects the reaction [Acetaminophen results in increased expression of and affects the localization of EGR1 protein]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of EGR1 mRNA] CTD PMID:27720869 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elmo2 engulfment and cell motility 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA] CTD PMID:19442820 NCBI chr 3:161,812,474...161,850,006
Ensembl chr 3:161,812,474...162,003,588
JBrowse link
G Erf Ets2 repressor factor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA] CTD PMID:19442820 NCBI chr 1:82,112,449...82,120,902
Ensembl chr 1:82,112,449...82,120,902
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of F3 protein] CTD PMID:27720869 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
ISO caffeic acid results in decreased expression of FASN mRNA
[Metformin co-treated with caffeic acid] results in decreased expression of FASN protein
CTD PMID:21870829, PMID:28576465 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA] CTD PMID:19442820 NCBI chr 6:119,518,459...119,613,534
Ensembl chr 6:119,519,714...119,609,296
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA] CTD PMID:19442820 NCBI chr10:35,078,782...35,120,296
Ensembl chr10:35,078,726...35,121,599
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO caffeic acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A mRNA]; caffeic acid inhibits the reaction [Acetaminophen results in increased expression of GADD45A protein] CTD PMID:27720869 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein] CTD PMID:20391626 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939
JBrowse link
G Gls glutaminase increases expression ISO caffeic acid results in increased expression of GLS protein CTD PMID:28576465 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15212457 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein]
caffeic acid inhibits the reaction [Acetaminophen results in increased activity of GPT protein]
CTD PMID:15212457, PMID:27720869 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO
caffeic acid inhibits the reaction [Cisplatin results in decreased activity of GSR protein]
caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]
CTD PMID:19442820, PMID:21640567, PMID:22036979 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity EXP caffeic acid results in decreased activity of GSTM1 protein CTD PMID:8340025 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases activity EXP caffeic acid results in decreased activity of GSTM2 protein CTD PMID:8340025 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity EXP caffeic acid results in decreased activity of GSTP1 protein CTD PMID:8340025 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:20391626 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions EXP caffeic acid inhibits the reaction [Cisplatin results in decreased activity of H6PD protein] CTD PMID:21640567 NCBI chr 5:166,994,683...167,030,441
Ensembl chr 5:166,998,881...167,030,441
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 multiple interactions ISO [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of HAVCR2 mRNA CTD PMID:16806235 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of HES1 mRNA] CTD PMID:29968957 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO caffeic acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO caffeic acid results in decreased expression of HMGCR mRNA CTD PMID:21870829 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA] CTD PMID:19442820 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA] CTD PMID:19442820 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of IFNG protein
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of IFNG protein]
CTD PMID:27378625, PMID:29968957 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 decreases expression ISO caffeic acid results in decreased expression of IL10 protein CTD PMID:27378625 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL1B protein]
CTD PMID:27368151, PMID:27720869 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases expression ISO caffeic acid results in increased expression of IL2 protein CTD PMID:27378625 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il21r interleukin 21 receptor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA] CTD PMID:19442820 NCBI chr 1:196,996,405...197,024,185
Ensembl chr 1:196,996,581...197,024,166
JBrowse link
G Il4 interleukin 4 decreases expression ISO caffeic acid results in decreased expression of IL4 protein CTD PMID:27378625 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of IL6 mRNA
caffeic acid inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]
caffeic acid inhibits the reaction [Aluminum results in increased expression of IL6 protein]
CTD PMID:21870829, PMID:27368151, PMID:27720869 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kif15 kinesin family member 15 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of KIF15 mRNA CTD PMID:19442820 NCBI chr 8:132,033,117...132,103,528
Ensembl chr 8:132,032,944...132,103,927
JBrowse link
G Kif20b kinesin family member 20B multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA] CTD PMID:19442820 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO caffeic acid inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA] CTD PMID:19442820 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:21472895 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions EXP caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:21472895 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO caffeic acid results in decreased activity of MAOA protein CTD PMID:27270453 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B decreases activity ISO caffeic acid results in decreased activity of MAOB protein CTD PMID:27270453 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in decreased expression of MAP2K5 mRNA CTD PMID:19442820 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK1 protein] CTD PMID:27720869 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK3 protein] CTD PMID:27720869 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MFN1 mRNA] CTD PMID:19442820 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases activity EXP caffeic acid results in increased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
ISO caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]
caffeic acid results in decreased activity of MPO protein
CTD PMID:22036979, PMID:24060682 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRPL45 mRNA] CTD PMID:19442820 NCBI chr10:85,257,876...85,269,806
Ensembl chr10:85,257,876...85,269,806
JBrowse link
G Mrrf mitochondrial ribosome recycling factor multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of MRRF mRNA] CTD PMID:19442820 NCBI chr 3:15,463,884...15,520,621
Ensembl chr 3:15,463,953...15,520,618
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [caffeic acid co-treated with Zymosan] results in increased expression of COX2 protein; caffeic acid inhibits the reaction [Zymosan results in increased expression of COX2 protein] CTD PMID:30481570 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Ndp norrin cystine knot growth factor NDP increases expression ISO caffeic acid results in increased expression of NDP mRNA CTD PMID:19442820 NCBI chr  X:6,791,090...6,815,586
Ensembl chr  X:6,791,136...6,815,583
Ensembl chr  X:6,791,136...6,815,583
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO
caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOS2 protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
CTD PMID:29968957, PMID:31306686 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO caffeic acid results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA] CTD PMID:29968957 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions
decreases activity
EXP caffeic acid inhibits the reaction [Caffeine results in decreased activity of NT5E protein]; Caffeine promotes the reaction [caffeic acid results in decreased activity of NT5E protein] CTD PMID:28465162 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G Pdcd10 programmed cell death 10 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PDCD10 mRNA] CTD PMID:19442820 NCBI chr 2:173,966,701...174,012,730
Ensembl chr 2:173,967,080...174,012,676
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO caffeic acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO caffeic acid results in increased expression of PIK3R1 mRNA CTD PMID:21870829 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in increased expression of PLK1 mRNA CTD PMID:19442820 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of PLK4 mRNA] CTD PMID:19442820 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO caffeic acid results in increased expression of PPARG mRNA CTD PMID:21870829 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdx5 peroxiredoxin 5 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PRDX5 mRNA] CTD PMID:19442820 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO caffeic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTGS2 mRNA]
CTD PMID:19442820, PMID:22036979, PMID:31306686 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of PTX3 mRNA] CTD PMID:19442820 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased phosphorylation of RAF1 protein] CTD PMID:27720869 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP caffeic acid inhibits the reaction [Valproic Acid results in increased expression of RELA protein] CTD PMID:29968957 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of SCD1 protein CTD PMID:28576465 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein] CTD PMID:27720869 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in decreased expression of SFXN4 mRNA] CTD PMID:19442820 NCBI chr 1:282,213,610...282,236,851
Ensembl chr 1:282,213,675...282,235,974
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO caffeic acid results in increased expression of SLC2A4 mRNA CTD PMID:21870829 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Snca synuclein alpha multiple interactions ISO caffeic acid inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Metformin co-treated with caffeic acid] results in decreased expression of SREBF1 protein CTD PMID:28576465 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Stk32a serine/threonine kinase 32A multiple interactions ISO [Thapsigargin co-treated with caffeic acid] results in decreased expression of STK32A mRNA CTD PMID:19442820 NCBI chr18:37,597,305...37,706,884
Ensembl chr18:37,597,156...37,710,306
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of caffeic acid CTD PMID:17433394 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases sulfation ISO SULT1C2 protein results in increased sulfation of caffeic acid CTD PMID:17433394 NCBI chr 9:4,152,588...4,168,355
Ensembl chr 9:4,152,589...4,168,221
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO
EXP
caffeic acid results in increased expression of TNF mRNA
caffeic acid inhibits the reaction [Aluminum results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Valproic Acid results in increased expression of TNF protein]
caffeic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]
CTD PMID:21870829, PMID:22036979, PMID:27368151, PMID:29968957, PMID:31306686 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 affects expression
multiple interactions
ISO caffeic acid affects the expression of TP53 protein
caffeic acid promotes the reaction [Thapsigargin results in decreased expression of TP53 mRNA]
CTD PMID:11522280, PMID:19442820 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tyr tyrosinase increases oxidation
multiple interactions
ISO TYR protein results in increased oxidation of caffeic acid
[TYR protein results in increased oxidation of caffeic acid] which results in decreased abundance of Glutathione
CTD PMID:20685355 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of UBE2C mRNA] CTD PMID:19442820 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of caffeic acid CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of caffeic acid CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vegfa vascular endothelial growth factor A decreases secretion ISO caffeic acid results in decreased secretion of VEGFA protein CTD PMID:27378625 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:22036979 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
docebenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type decreases activity ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in decreased activity of ALOX12 protein CTD PMID:23238474 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity ISO
EXP
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in decreased activity of ALOX5 protein CTD PMID:2724698, PMID:7812673, PMID:25432964 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]] CTD PMID:25432964 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased cleavage of CASP8 protein]] CTD PMID:25432964 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 increases activity
multiple interactions
ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in increased activity of HSD11B2 protein
[2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone co-treated with Leukotriene B4] results in decreased expression of HSD11B2 protein; Leukotriene B4 inhibits the reaction [2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in increased activity of HSD11B2 protein]
CTD PMID:18032417 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO [2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone co-treated with 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide] results in decreased expression of IL6 mRNA
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in decreased expression of IL6 mRNA
CTD PMID:17766677 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:7812673 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Osmr oncostatin M receptor multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of OSMR mRNA]] CTD PMID:25432964 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of OSMR mRNA]]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased cleavage of CASP8 protein]]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of TNF protein]] CTD PMID:25432964 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein] CTD PMID:17925309 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Arachidonic Acid results in decreased activity of SOD1 protein] CTD PMID:16982041 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Arachidonic Acid results in increased activity of SOD2 protein] CTD PMID:16982041 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of STAT3 protein]] CTD PMID:25432964 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [endotoxin, Escherichia coli results in increased secretion of TNF protein]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of TNF protein]]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone promotes the reaction [endotoxin, Escherichia coli results in increased expression of TNF mRNA]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone results in increased stability of and affects the expression of TNF mRNA CTD PMID:15060681, PMID:25432964 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
E3040 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of E 3040 analog CTD PMID:19628752 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects export ISO ABCG2 protein affects the export of E 3040 analog CTD PMID:15598971 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO E 3040 inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
ebselen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:16757516 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO ebselen inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP ebselen inhibits the reaction [Aflatoxin B1 results in increased expression of AFP mRNA] CTD PMID:11133813 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
EXP
ISO
Dithiothreitol inhibits the reaction [ebselen results in decreased activity of ALAD protein]
ebselen inhibits the reaction [Cadmium Chloride results in decreased activity of ALAD protein]
CTD PMID:14630126, PMID:17624921, PMID:23933410 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity ISO ebselen results in decreased activity of ALOX5 protein CTD PMID:7590103 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of BAX protein] CTD PMID:30558456 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein] CTD PMID:30558456 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP3 protein]
ebselen results in increased activity of CASP3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; ebselen inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]
CTD PMID:21300091, PMID:23649643, PMID:25068500, PMID:30558456 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO
EXP
ebselen inhibits the reaction [Mechlorethamine results in increased activity of CASP9 protein]
ebselen inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]
CTD PMID:18629305, PMID:23649643 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP ebselen results in increased activity of CAT protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:27282967, PMID:30558456 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 increases expression ISO ebselen results in increased expression of COX4I1 protein CTD PMID:27385396 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cs citrate synthase multiple interactions ISO ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA] CTD PMID:11903743 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP ebselen results in increased phosphorylation of EIF2S1 protein CTD PMID:27282967 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO ebselen binds to and results in decreased activity of EPHX2 protein CTD PMID:23219563 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO ebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of FOS protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of FOS protein] CTD PMID:14572605 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gck glucokinase multiple interactions ISO [ebselen co-treated with Glucose] results in increased activity of GCK protein CTD PMID:23795780 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gfap glial fibrillary acidic protein increases phosphorylation EXP ebselen results in increased phosphorylation of GFAP protein CTD PMID:27282967 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 mRNA]; ebselen inhibits the reaction [Oxygen deficiency results in increased expression of GJA1 protein] CTD PMID:12958040 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO ebselen inhibits the reaction [GPX1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
ebselen inhibits the reaction [Methylmercury Compounds results in decreased activity of GPX1 protein]
CTD PMID:23795780, PMID:28383113 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
multiple interactions
EXP ebselen results in increased activity of GSR protein
ebselen inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]
CTD PMID:27282967, PMID:30558456 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein] CTD PMID:8147899 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTA1 protein binds to GSTA3 protein]; ebselen binds to and results in decreased activity of GSTA3 protein CTD PMID:8147899 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein] CTD PMID:8147899 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions EXP ebselen binds to and results in decreased activity of GSTP1 protein CTD PMID:8147899 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]] CTD PMID:19374849 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [ebselen affects the abundance of Reactive Oxygen Species] which results in decreased expression of HMOX1 protein; [ebselen affects the abundance of Reactive Oxygen Species] which results in increased activity of HMOX1 protein CTD PMID:16959961 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase increases expression ISO ebselen results in increased expression of HPGDS mRNA CTD PMID:21669866 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Ifng interferon gamma multiple interactions ISO ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] CTD PMID:12794164 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il6 interleukin 6 multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of IL6 protein] CTD PMID:30558456 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen results in increased activity of MAPK1 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK1 protein]
ebselen analog results in increased phosphorylation of MAPK1 protein; ebselen results in increased phosphorylation of MAPK1 protein
CTD PMID:20495008, PMID:21300091, PMID:21960664, PMID:22001386, PMID:27282967 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
ebselen results in increased activity of MAPK3 protein
ebselen analog results in increased phosphorylation of MAPK3 protein; ebselen results in increased phosphorylation of MAPK3 protein
ebselen inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; ebselen inhibits the reaction [tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:20495008, PMID:21300091, PMID:21960664, PMID:22001386, PMID:27282967 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation EXP ebselen results in increased phosphorylation of MAPK9 protein CTD PMID:27282967 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP13 mRNA] CTD PMID:11903743 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Ngf nerve growth factor multiple interactions ISO ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [NGF protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO
EXP
ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; ebselen inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein]
ebselen results in decreased activity of NOS2 protein
CTD PMID:7590103, PMID:12794164 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity EXP ebselen results in decreased activity of NQO1 protein CTD PMID:7590103 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 multiple interactions ISO [ebselen co-treated with Glucose] results in increased expression of PDX1 protein CTD PMID:23795780 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 decreases activity ISO ebselen results in decreased activity of PHOSPHO1 protein CTD PMID:17227223 NCBI chr10:83,635,557...83,643,862
Ensembl chr10:83,636,518...83,643,859
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO ebselen inhibits the reaction [Lipopolysaccharides affects the localization of and affects the activity of RELA protein]; ebselen inhibits the reaction [Peroxynitrous Acid affects the localization of and affects the activity of RELA protein] CTD PMID:14572605 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO ebselen inhibits the reaction [SLC11A2 protein results in increased uptake of Iron] CTD PMID:16984886 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions ISO [ebselen co-treated with Glucose] results in increased expression of SLC2A2 protein CTD PMID:23795780 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein] CTD PMID:21131394 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod1 superoxide dismutase 1 decreases response to substance
multiple interactions
ISO ebselen results in decreased susceptibility to SOD1 protein mutant form
ebselen inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]
CTD PMID:16702190, PMID:23795780 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; ebselen inhibits the reaction [SOD2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20495008 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]
ebselen inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; ebselen inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
CTD PMID:11903743, PMID:16757516, PMID:21131394 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:11903743 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ebselen inhibits the reaction [sodium arsenite results in increased expression of TNF protein] CTD PMID:30558456 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO ebselen results in increased expression of and results in increased activity of TXNRD1 protein CTD PMID:28383113 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [ebselen co-treated with Glucose] results in decreased expression of UCP2 protein CTD PMID:23795780 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Xbp1 X-box binding protein 1 increases phosphorylation EXP ebselen results in increased phosphorylation of XBP1 protein CTD PMID:27282967 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor multiple interactions ISO ebselen inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928
JBrowse link
ethyl trans-caffeate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO ethyl caffeate affects the phosphorylation of and affects the activity of AKT1 protein CTD PMID:24892518 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Cdh2 cadherin 2 affects expression ISO ethyl caffeate affects the expression of CDH2 protein CTD PMID:24892518 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk2 cyclin dependent kinase 2 affects expression ISO ethyl caffeate affects the expression of CDK2 protein CTD PMID:24892518 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO ethyl caffeate affects the expression of CDK4 protein CTD PMID:24892518 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects expression
multiple interactions
ISO ethyl caffeate affects the expression of ERBB2 protein
ethyl caffeate affects the phosphorylation of and affects the activity of ERBB2 protein
CTD PMID:24892518 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 affects expression ISO ethyl caffeate affects the expression of FGFR1 protein CTD PMID:24892518 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Ilk integrin-linked kinase affects expression ISO ethyl caffeate affects the expression of ILK protein CTD PMID:24892518 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions ISO ethyl caffeate affects the expression of [ITGA3 protein binds to ITGB1 protein] CTD PMID:24892518 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO ethyl caffeate affects the expression of [ITGA3 protein binds to ITGB1 protein] CTD PMID:24892518 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Kdr kinase insert domain receptor affects expression ISO ethyl caffeate affects the expression of KDR protein CTD PMID:24892518 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO ethyl caffeate affects the phosphorylation of and affects the activity of MAPK1 protein CTD PMID:24892518 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO ethyl caffeate affects the phosphorylation of and affects the activity of MAPK3 protein CTD PMID:24892518 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects phosphorylation ISO ethyl caffeate affects the phosphorylation of RB1 protein CTD PMID:24892518 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
eupatilin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CCL2 mRNA] CTD PMID:21565208 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA] CTD PMID:21565208 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA] CTD PMID:21565208 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:21565208 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 mRNA]; eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 protein] CTD PMID:21565208 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 mRNA]; eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 protein] CTD PMID:21565208 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of RELA protein] CTD PMID:21565208 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO eupatilin inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA] CTD PMID:21565208 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
ginkgetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO ginkgetin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of BAX protein]
ginkgetin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]
CTD PMID:25968939 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO ginkgetin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]
ginkgetin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of BCL2 protein]
CTD PMID:25968939 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO ginkgetin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP3 protein] CTD PMID:25968939 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression ISO ginkgetin results in decreased expression of FTL1 protein
ginkgetin results in decreased expression of FTL protein
CTD PMID:25968939 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Tfrc transferrin receptor increases expression ISO ginkgetin results in increased expression of TFRC protein CTD PMID:25968939 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO ginkgetin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:25968939 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
meclofenamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Meclofenamic Acid results in decreased activity of AKR1C4 protein CTD PMID:27163852 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Meclofenamic Acid results in decreased activity of AKR1C2 protein CTD PMID:19010312, PMID:26362498, PMID:27163852 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Meclofenamic Acid results in decreased activity of AKR1C3 protein CTD PMID:19010312, PMID:26362498, PMID:27163852 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases activity ISO Meclofenamic Acid results in decreased activity of ALOX5 protein CTD PMID:3020588 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Ren renin multiple interactions EXP Meclofenamic Acid inhibits the reaction [Yohimbine results in increased expression of REN protein] CTD PMID:6323192 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Sell selectin L decreases expression ISO Meclofenamic Acid results in decreased expression of SELL protein CTD PMID:12147693 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO Meclofenamic Acid inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases activity ISO Meclofenamic Acid results in decreased activity of SULT1A1 protein CTD PMID:17073578 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases activity ISO Meclofenamic Acid results in decreased activity of SULT1E1 protein CTD PMID:17073578 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Meclofenamic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:10328874 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO Meclofenamic Acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Meclofenamic Acid inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Aldosterone] CTD PMID:19740398 NCBI chr14:22,597,103...22,619,968 JBrowse link
methyl caffeate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of AKT1 protein CTD PMID:25481497 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO methyl caffeate results in increased expression of BAX protein CTD PMID:26415618 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO methyl caffeate binds to and results in decreased expression of BCL2 protein CTD PMID:26415618 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO methyl caffeate results in increased expression of BID protein CTD PMID:26415618 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp3 caspase 3 increases activity ISO methyl caffeate results in increased activity of CASP3 protein CTD PMID:26415618 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO methyl caffeate analog results in increased expression of CDKN1A protein CTD PMID:25481497 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO methyl caffeate analog results in decreased expression of KDR protein CTD PMID:25481497 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of MAPK1 protein CTD PMID:25481497 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of MAPK3 protein CTD PMID:25481497 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mdm2 MDM2 proto-oncogene affects binding ISO methyl caffeate binds to MDM2 protein CTD PMID:26415618 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO methyl caffeate analog results in decreased expression of and results in decreased activity of MMP2 protein CTD PMID:25481497 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO methyl caffeate analog results in decreased expression of and results in decreased activity of MMP9 protein CTD PMID:25481497 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO methyl caffeate analog results in decreased phosphorylation of MTOR protein CTD PMID:25481497 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO methyl caffeate binds to and results in increased activity of PARP1 protein CTD PMID:26415618 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Tp53 tumor protein p53 increases expression ISO methyl caffeate analog results in increased expression of TP53 protein CTD PMID:25481497 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO methyl caffeate analog results in decreased expression of and results in decreased secretion of VEGFA protein CTD PMID:25481497 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
phenethyl caffeate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of A2M mRNA] CTD PMID:20360939 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Aanat aralkylamine N-acetyltransferase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AANAT mRNA CTD PMID:20360939 NCBI chr10:105,568,091...105,572,407
Ensembl chr10:105,568,091...105,572,403
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCA5 mRNA CTD PMID:20360939 NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO caffeic acid phenethyl ester metabolite results in decreased activity of ABCC1 protein CTD PMID:15885658 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA CTD PMID:20360939 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Acan aggrecan multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACAN mRNA CTD PMID:20360939 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACOT2 mRNA CTD PMID:20360939 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of ACP5 protein] CTD PMID:28363435 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Ada adenosine deaminase multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Methotrexate results in increased activity of ADA protein] CTD PMID:16325979 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adam7 ADAM metallopeptidase domain 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADAM7 mRNA CTD PMID:20360939 NCBI chr15:49,418,946...49,467,174
Ensembl chr15:49,418,946...49,467,174
JBrowse link
G Adcy2 adenylate cyclase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADCY2 mRNA CTD PMID:20360939 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADRA1D mRNA CTD PMID:20360939 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AGAP2 mRNA CTD PMID:20360939 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO caffeic acid phenethyl ester promotes the reaction [Nitrogen Mustard Compounds results in decreased expression of AHR protein] CTD PMID:17204746 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA] CTD PMID:16365417 NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378
JBrowse link
G Akap9 A-kinase anchoring protein 9 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AKAP9 mRNA CTD PMID:20360939 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1B1 protein CTD PMID:27163852 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1B10 protein CTD PMID:27163852 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1C4 protein CTD PMID:27163852 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1C2 protein CTD PMID:27163852 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO caffeic acid phenethyl ester results in decreased activity of AKR1C3 protein CTD PMID:27163852 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation ISO caffeic acid phenethyl ester analog affects the phosphorylation of AKT1 protein CTD PMID:32125059 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ALDH1A2 mRNA CTD PMID:20360939 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO
EXP
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of ALPL protein]
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of ALPL protein]
CTD PMID:18436364, PMID:28363435 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Ankrd17 ankyrin repeat domain 17 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ANKRD17 mRNA] CTD PMID:20360939 NCBI chr14:19,291,025...19,431,521
Ensembl chr14:19,318,565...19,431,515
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ARRB1 mRNA CTD PMID:20360939 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ATF6 mRNA] CTD PMID:28223344 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atox1 antioxidant 1 copper chaperone multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ATOX1 mRNA] CTD PMID:20360939 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Axl Axl receptor tyrosine kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AXL mRNA CTD PMID:20360939 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of BAX mRNA CTD PMID:24289642 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases phosphorylation ISO caffeic acid phenethyl ester results in decreased phosphorylation of BCAR1 protein CTD PMID:10741720 NCBI chr19:43,932,543...43,967,452
Ensembl chr19:43,932,554...43,955,783
JBrowse link
G Bgn biglycan multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of BGN mRNA CTD PMID:20360939 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of BIRC2 protein CTD PMID:15291876 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of BIRC3 protein CTD PMID:15291876 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAR3 mRNA] CTD PMID:20360939 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Ca4 carbonic anhydrase 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAR4 mRNA CTD PMID:20360939 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1A mRNA CTD PMID:20360939 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1H mRNA CTD PMID:20360939 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAMK2D mRNA CTD PMID:20360939 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Capn8 calpain 8 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAPN8 mRNA] CTD PMID:20360939 NCBI chr13:100,980,149...101,043,110
Ensembl chr13:100,980,574...101,043,110
JBrowse link
G Casp1 caspase 1 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of CASP1 protein CTD PMID:15469948 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 decreases activity
increases activity
multiple interactions
EXP
ISO
caffeic acid phenethyl ester results in decreased activity of CASP3 protein
caffeic acid phenethyl ester analog results in increased activity of CASP3 protein
caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in increased activity of CASP3 protein]
caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]
CTD PMID:15469948, PMID:18436364, PMID:28363435, PMID:32125059 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP8 protein] CTD PMID:18436364 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions EXP
ISO
caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; caffeic acid phenethyl ester promotes the reaction [Doxorubicin results in increased activity of CAT protein]
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]
CTD PMID:14745846, PMID:15369732, PMID:18436364, PMID:23570914 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of CCL2 mRNA] CTD PMID:16085347 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CCL5 mRNA CTD PMID:20360939 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of CCNB1 protein CTD PMID:16085347 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased expression of CCND1 mRNA; caffeic acid phenethyl ester inhibits the reaction [sodium arsenite results in increased expression of CCND1 protein] CTD PMID:20420878, PMID:24289642 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP
ISO
caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein]
[Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein]
CTD PMID:15885897, PMID:16766008 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd14 CD14 molecule multiple interactions
increases expression
EXP
ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD14 mRNA
caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of CD14 protein]
caffeic acid phenethyl ester results in increased expression of CD14 protein
CTD PMID:16766008, PMID:20360939 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd151 CD151 molecule (Raph blood group) multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD151 mRNA CTD PMID:20360939 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cd86 CD86 molecule multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD86 mRNA CTD PMID:20360939 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of CDK1 protein CTD PMID:16085347 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP
ISO
caffeic acid phenethyl ester inhibits the reaction [CDK2 protein binds to CCNE1 protein]
[Tretinoin co-treated with caffeic acid phenethyl ester] inhibits the reaction [CDK2 protein binds to CCNE1 protein]
CTD PMID:15885897, PMID:16766008 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
caffeic acid phenethyl ester results in increased expression of CDKN1A protein
[Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of CDKN1A mRNA; caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein]; Tretinoin promotes the reaction [caffeic acid phenethyl ester results in increased expression of CDKN1A protein]
CTD PMID:15885897, PMID:16766008, PMID:24289642, PMID:26056802 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
EXP
ISO
caffeic acid phenethyl ester results in increased expression of CDKN1B protein
caffeic acid phenethyl ester inhibits the reaction [Folic Acid results in increased expression of CDKN1B protein]
CTD PMID:15885897, PMID:26056802 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
EXP caffeic acid phenethyl ester results in increased expression of CDKN2A protein
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA]
CTD PMID:15885897, PMID:20360939 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CDKN2C mRNA CTD PMID:20360939 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CEACAM10 mRNA CTD PMID:20360939 NCBI chr 1:81,643,809...81,650,085
Ensembl chr 1:81,643,816...81,650,094
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon multiple interactions
increases expression
ISO Tretinoin promotes the reaction [caffeic acid phenethyl ester results in increased expression of CEBPE protein] CTD PMID:16766008 NCBI chr15:33,356,119...33,357,517
Ensembl chr15:33,355,947...33,358,138
JBrowse link
G Cers2 ceramide synthase 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS2 mRNA] CTD PMID:28223344 NCBI chr 2:196,487,656...196,495,930
Ensembl chr 2:196,487,656...196,496,986
JBrowse link
G Cers4 ceramide synthase 4 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of CERS4 mRNA] CTD PMID:28223344 NCBI chr12:4,439,750...4,474,759
Ensembl chr12:4,439,750...4,474,729
JBrowse link
G Cgm4 carcinoembryonic antigen gene family 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CGM4 mRNA CTD PMID:20360939 NCBI chr 1:79,030,291...79,043,259
Ensembl chr 1:79,030,291...79,080,881
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CHRNA2 mRNA CTD PMID:20360939 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CHRNE mRNA CTD PMID:20360939 NCBI chr10:57,238,960...57,246,750
Ensembl chr10:57,238,946...57,243,435
JBrowse link
G Clcn1 chloride voltage-gated channel 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CLCN1 mRNA] CTD PMID:20360939 NCBI chr 4:71,674,218...71,704,318
Ensembl chr 4:71,675,383...71,702,819
JBrowse link
G Cldn2 claudin 2 decreases expression
multiple interactions
ISO caffeic acid phenethyl ester results in decreased expression of CLDN2 mRNA; caffeic acid phenethyl ester results in decreased expression of CLDN2 protein
Cantharidin inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein]; Chloroquine inhibits the reaction [caffeic acid phenethyl ester results in decreased expression of CLDN2 protein]; CLDN2 protein inhibits the reaction [caffeic acid phenethyl ester results in increased susceptibility to and results in increased activity of Doxorubicin]
CTD PMID:29597147 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Cldn7 claudin 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLDN7 mRNA CTD PMID:20360939 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Clic5 chloride intracellular channel 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLIC5 mRNA CTD PMID:20360939 NCBI chr 9:19,121,676...19,372,673
Ensembl chr 9:19,121,677...19,372,673
JBrowse link
G Clock clock circadian regulator multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLOCK mRNA CTD PMID:20360939 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO caffeic acid phenethyl ester results in increased expression of COL18A1 protein CTD PMID:20433813 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Cox4i2 cytochrome c oxidase subunit 4i2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX4I2 mRNA CTD PMID:20360939 NCBI chr 3:148,234,546...148,245,424
Ensembl chr 3:148,234,193...148,245,416
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX6A2 mRNA CTD PMID:20360939 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of COX7A2 mRNA] CTD PMID:20360939 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Crmp1 collapsin response mediator protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRMP1 mRNA CTD PMID:20360939 NCBI chr14:78,266,931...78,312,777
Ensembl chr14:78,266,931...78,308,933
JBrowse link
G Cs citrate synthase multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein; [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased activity of CS protein]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of CS mRNA] CTD PMID:28223344 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csk C-terminal Src kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSK mRNA CTD PMID:20360939 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSPG4 mRNA CTD PMID:20360939 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of CTNNB1 protein CTD PMID:10783313 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsk cathepsin K multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CTSK mRNA CTD PMID:20360939 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CXCR3 mRNA CTD PMID:20360939 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYB5A mRNA] CTD PMID:20360939 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CYBA mRNA] CTD PMID:20360939 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein] CTD PMID:15469948 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases expression
EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA
caffeic acid phenethyl ester results in decreased expression of CYP1A2 protein
CTD PMID:20360939, PMID:22291063 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2A2 mRNA CTD PMID:20360939 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression
EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2B1 mRNA
caffeic acid phenethyl ester results in decreased expression of CYP2B1 protein
CTD PMID:20360939, PMID:22291063 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of CYP2B2 protein CTD PMID:22291063 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2C13 mRNA] CTD PMID:20360939 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA
caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]
CTD PMID:18436364, PMID:20360939 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP3A18 mRNA] CTD PMID:20360939 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyth2 cytohesin 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CYTH2 mRNA CTD PMID:20360939 NCBI chr 1:101,796,349...101,803,407
Ensembl chr 1:101,796,349...101,803,200
JBrowse link
G Dbn1 drebrin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DBN1 mRNA CTD PMID:20360939 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DDIT3 mRNA] CTD PMID:28223344 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Deaf1 DEAF1 transcription factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DEAF1 mRNA CTD PMID:20360939 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DEGS1 mRNA CTD PMID:20360939 NCBI chr13:100,665,265...100,672,731
Ensembl chr13:100,666,075...100,672,731
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of DEGS2 mRNA] CTD PMID:28223344 NCBI chr 6:132,591,968...132,608,600
Ensembl chr 6:132,591,969...132,608,600
JBrowse link
G Dgkb diacylglycerol kinase, beta multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DGKB mRNA CTD PMID:20360939 NCBI chr 6:57,516,351...58,277,385
Ensembl chr 6:57,516,713...58,277,279
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DHFR mRNA CTD PMID:20360939 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Disc1 DISC1 scaffold protein multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of DISC1 mRNA] CTD PMID:20360939 NCBI chr19:57,818,838...58,069,992
Ensembl chr19:57,820,260...58,066,152
JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DMRT1 mRNA CTD PMID:20360939 NCBI chr 1:243,477,403...243,582,629
Ensembl chr 1:243,477,493...243,582,629
JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH10 mRNA CTD PMID:20360939 NCBI chr12:37,237,482...37,365,258 JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH5 mRNA CTD PMID:20360939 NCBI chr 2:80,947,730...81,143,997
NCBI chr 2:81,159,060...81,337,560
Ensembl chr 2:80,948,658...81,143,447
JBrowse link
G Dpys dihydropyrimidinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DPYS mRNA CTD PMID:20360939 NCBI chr 7:78,769,918...78,847,941
Ensembl chr 7:78,769,807...78,847,974
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DUSP6 mRNA CTD PMID:20360939 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G E2f6 E2F transcription factor 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of E2F6 mRNA CTD PMID:20360939 NCBI chr 6:42,092,513...42,108,692
Ensembl chr 6:42,092,467...42,108,702
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ECHS1 mRNA CTD PMID:20360939 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:21926265 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ETS1 mRNA CTD PMID:20360939 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Fabp7 fatty acid binding protein 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FABP7 mRNA CTD PMID:20360939 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased expression of FAS protein] CTD PMID:18436364 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased expression of FASL protein] CTD PMID:18436364 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of FGF15 mRNA] CTD PMID:28223344 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FGF7 mRNA CTD PMID:20360939 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of FGG mRNA CTD PMID:20360939 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FMO2 mRNA CTD PMID:20360939 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Foxc2 forkhead box C2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FOXC2 mRNA CTD PMID:20360939 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Foxd1 forkhead box D1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FOXD1 mRNA CTD PMID:20360939 NCBI chr 2:28,460,068...28,462,488
Ensembl chr 2:28,460,068...28,462,488
JBrowse link
G Frmd6 FERM domain containing 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FRMD6 mRNA CTD PMID:20360939 NCBI chr 6:93,281,382...93,358,888
Ensembl chr 6:93,281,408...93,358,840
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FTL mRNA CTD PMID:20360939 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fut2 fucosyltransferase 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of FUT2 mRNA CTD PMID:20360939 NCBI chr 1:101,631,633...101,651,668
Ensembl chr 1:101,631,635...101,651,668
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GAS6 mRNA CTD PMID:20360939 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gc GC, vitamin D binding protein multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNA CTD PMID:20360939 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gch1 GTP cyclohydrolase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GCH1 mRNA CTD PMID:20360939 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GDNF mRNA CTD PMID:20360939 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
EXP NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of GFAP protein] CTD PMID:20836997 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfer growth factor, augmenter of liver regeneration multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GFER mRNA CTD PMID:20360939 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Gfra4 GDNF family receptor alpha 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GFRA4 mRNA CTD PMID:20360939 NCBI chr 3:123,573,394...123,582,431
Ensembl chr 3:123,578,997...123,581,518
JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GHR mRNA CTD PMID:20360939 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B protein] CTD PMID:15350541 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjc2 gap junction protein, gamma 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GJC2 mRNA CTD PMID:20360939 NCBI chr10:45,526,740...45,535,520
Ensembl chr10:45,526,745...45,534,570
JBrowse link
G Gls glutaminase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GLS mRNA CTD PMID:20360939 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gnal G protein subunit alpha L multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GNAL mRNA CTD PMID:20360939 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
JBrowse link
G Golga2 golgin A2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GOLGA2 mRNA CTD PMID:20360939 NCBI chr 3:11,317,328...11,337,569
Ensembl chr 3:11,317,183...11,336,458
JBrowse link
G Gpr19 G protein-coupled receptor 19 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GPR19 mRNA CTD PMID:20360939 NCBI chr 4:168,639,930...168,668,345
Ensembl chr 4:168,639,940...168,656,673
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GRIK2 mRNA CTD PMID:20360939 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GRIK5 mRNA CTD PMID:20360939 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of GSR mRNA CTD PMID:20360939 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of GSTK1 mRNA] CTD PMID:20360939 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of GSTP1 protein CTD PMID:17106925 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of GSTT2 mRNA] CTD PMID:20360939 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gyg1 glycogenin 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GYG1 mRNA CTD PMID:20360939 NCBI chr 2:104,916,734...104,958,219
Ensembl chr 2:104,916,738...104,958,034
JBrowse link
G H2ac1 H2A clustered histone 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of H2AC1 mRNA CTD PMID:20360939 NCBI chr17:43,422,454...43,422,846
Ensembl chr17:43,422,454...43,422,846
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HAMP mRNA CTD PMID:20360939 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hdgf heparin binding growth factor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of HDGF mRNA CTD PMID:20360939 NCBI chr 2:187,274,898...187,284,670
Ensembl chr 2:187,275,120...187,284,281
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of HMGCS2 mRNA] CTD PMID:20360939 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
caffeic acid phenethyl ester results in increased expression of HMOX1 protein
caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of HMOX1 protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]
caffeic acid phenethyl ester analog results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester analog results in increased expression of HMOX1 protein; caffeic acid phenethyl ester results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester results in increased expression of HMOX1 protein
CTD PMID:20226179, PMID:20950636, PMID:21472898, PMID:23942037, PMID:24508943 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HNRNPR mRNA CTD PMID:20360939 NCBI chr 5:154,668,194...154,699,967
Ensembl chr 5:154,668,179...154,699,966
JBrowse link
G Hpcal4 hippocalcin-like 4 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HPCAL4 mRNA CTD PMID:20360939 NCBI chr 5:140,870,127...140,882,242
Ensembl chr 5:140,870,140...140,882,244
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPA2 mRNA CTD PMID:20360939 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of HSPA5 mRNA] CTD PMID:28223344 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPB1 mRNA CTD PMID:20360939 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb2 heat shock protein family B (small) member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HSPB2 mRNA CTD PMID:20360939 NCBI chr 8:55,176,648...55,178,227
Ensembl chr 8:55,176,847...55,177,818
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3A mRNA] CTD PMID:28223344 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3B mRNA] CTD PMID:28223344 NCBI chr 3:122,808,564...122,813,638
Ensembl chr 3:122,808,564...122,813,583
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in increased expression of IDH3G mRNA] CTD PMID:28223344 NCBI chr  X:156,999,803...157,008,735
Ensembl chr  X:156,999,826...157,008,733
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IDO1 mRNA CTD PMID:20360939 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased expression of IFNG protein; caffeic acid phenethyl ester inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] CTD PMID:18953428, PMID:24289642 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igbp1 immunoglobulin binding protein 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IGBP1 mRNA CTD PMID:20360939 NCBI chr  X:70,322,764...70,345,005
Ensembl chr  X:70,322,755...70,345,005
JBrowse link
G Il12b interleukin 12B multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [AIMP1 protein results in increased expression of IL12B mRNA] CTD PMID:16365417 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il18 interleukin 18 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL18 mRNA] CTD PMID:16085347 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL1A mRNA] CTD PMID:16085347 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of IL1B mRNA; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [GJB1 protein results in decreased expression of IL1B protein] CTD PMID:15350541, PMID:20360939 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL2 mRNA] CTD PMID:16085347 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Insrr insulin receptor-related receptor multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of INSRR mRNA CTD PMID:20360939 NCBI chr 2:187,161,817...187,181,400
Ensembl chr 2:187,162,017...187,181,395
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of IP6K2 mRNA] CTD PMID:20360939 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO caffeic acid phenethyl ester results in decreased expression of IRS1 mRNA CTD PMID:21467634 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
ISO caffeic acid phenethyl ester promotes the reaction [Tretinoin results in increased expression of ITGAM protein]
caffeic acid phenethyl ester results in increased expression of ITGAM protein
CTD PMID:16766008 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA]; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR1 mRNA] CTD PMID:28223344 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA; NR1H4 protein affects the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of ITPR2 mRNA] CTD PMID:28223344 NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO caffeic acid phenethyl ester inhibits the reaction [arsenite results in increased expression of JUN mRNA] CTD PMID:16085347 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kalrn kalirin, RhoGEF kinase multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KALRN mRNA CTD PMID:20360939 NCBI chr11:69,484,293...70,025,682
Ensembl chr11:69,484,293...70,025,633
JBrowse link
G Kcng3 potassium voltage-gated channel modifier subfamily G member 3 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KCNG3 mRNA] CTD PMID:20360939 NCBI chr 6:6,794,808...6,842,758
Ensembl chr 6:6,794,808...6,842,758
JBrowse link
G Kcnh5 potassium voltage-gated channel subfamily H member 5 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNH5 mRNA CTD PMID:20360939 NCBI chr 6:97,872,831...98,157,087
Ensembl chr 6:97,872,831...98,157,087
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of KCNJ2 mRNA CTD PMID:20360939 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnmb2 potassium calcium-activated channel subfamily M regulatory beta subunit 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNMB2 mRNA CTD PMID:20360939 NCBI chr 2:118,276,298...118,585,321
Ensembl chr 2:118,546,829...118,586,699
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KCNQ2 mRNA CTD PMID:20360939 NCBI chr 3:176,585,897...176,645,029
Ensembl chr 3:176,589,906...176,644,951
JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 decreases expression EXP caffeic acid phenethyl ester results in decreased expression of KCNT2 mRNA CTD PMID:26100633 NCBI chr13:57,130,855...57,520,263
Ensembl chr13:57,131,395...57,521,836
JBrowse link
G Kif6 kinesin family member 6 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of KIF6 mRNA] CTD PMID:20360939 NCBI chr 9:13,016,973...13,311,971
Ensembl chr 9:13,030,673...13,311,924
JBrowse link
G Klhl17 kelch-like family member 17 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of KLHL17 mRNA CTD PMID:20360939 NCBI chr 5:173,654,238...173,659,706
Ensembl chr 5:173,654,860...173,659,675
JBrowse link
G Lalba lactalbumin, alpha multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LALBA mRNA CTD PMID:20360939 NCBI chr 7:140,088,420...140,096,347
Ensembl chr 7:140,088,421...140,090,922
JBrowse link
G Lep leptin decreases expression ISO caffeic acid phenethyl ester results in decreased expression of LEP mRNA; caffeic acid phenethyl ester results in decreased expression of LEP protein CTD PMID:21467634 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Leprot leptin receptor overlapping transcript multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LEPROT mRNA CTD PMID:20360939 NCBI chr 5:120,498,910...120,511,011
Ensembl chr 5:120,498,883...120,511,017
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LGI1 mRNA CTD PMID:20360939 NCBI chr 1:256,955,944...256,996,835
Ensembl chr 1:256,955,652...256,999,253
JBrowse link
G Lmna lamin A/C multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LMNA mRNA CTD PMID:20360939 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC100363405 hypothetical LOC100363405 multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP37 mRNA] CTD PMID:20360939 NCBI chr 5:77,265,335...77,294,739
Ensembl chr 5:77,266,842...77,294,765
JBrowse link
G Lrrc15 leucine rich repeat containing 15 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LRRC15 mRNA CTD PMID:20360939 NCBI chr11:74,040,846...74,052,179
Ensembl chr11:74,050,166...74,051,902
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation ISO caffeic acid phenethyl ester analog affects the phosphorylation of MAPK1 protein CTD PMID:32125059 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA CTD PMID:20360939 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation ISO caffeic acid phenethyl ester analog affects the phosphorylation of MAPK3 protein CTD PMID:32125059 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Me1 malic enzyme 1 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ME1 mRNA CTD PMID:20360939 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA; GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of MFN2 mRNA] CTD PMID:28223344 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
EXP caffeic acid phenethyl ester results in decreased activity of MMP2 protein
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP2 protein]
CTD PMID:20836997 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions EXP [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MMP3 mRNA CTD PMID:20360939 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
decreases activity
multiple interactions
ISO
EXP
caffeic acid phenethyl ester results in decreased expression of MMP9 protein
caffeic acid phenethyl ester results in decreased activity of MMP9 protein
NGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in decreased activity of MMP9 protein]
CTD PMID:20433813, PMID:20836997 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP caffeic acid phenethyl ester inhibits the reaction [Doxorubicin results in increased activity of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:15369732, PMID:20693123, PMID:21472898 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260