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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trivalent inorganic cation
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Accession:CHEBI:64712 term browser browse the term
Definition:An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of three.



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chromium trinitrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha-2-HS-glycoprotein decreases expression ISO chromium nitrate results in decreased expression of AHSG protein CTD PMID:23618972 NCBI chr11:78,117,903...78,145,956
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO chromium nitrate results in increased expression of ALDH1L2 protein CTD PMID:22144121 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776
JBrowse link
G Apcs amyloid P component, serum increases expression ISO chromium nitrate results in increased expression of APCS protein CTD PMID:23618972 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO chromium nitrate results in decreased expression of APOA1 protein CTD PMID:23618972 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO chromium nitrate results in increased expression of ATP5B protein CTD PMID:19771553 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta decreases expression ISO chromium nitrate results in decreased expression of BCKDHB protein CTD PMID:22144121 NCBI chr 8:84,845,264...85,027,812
Ensembl chr 8:84,845,264...85,027,812
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO chromium nitrate results in decreased expression of CCT5 protein CTD PMID:22144121 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO chromium nitrate results in increased expression of CES1D protein CTD PMID:22144121 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 increases expression ISO chromium nitrate results in increased expression of DBT protein CTD PMID:22144121 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO chromium nitrate results in decreased expression of DDAH1 protein CTD PMID:22144121 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO chromium nitrate results in increased expression of ECH1 protein CTD PMID:22144121 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO chromium nitrate results in increased expression of FBP1 protein CTD PMID:22144121 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fgb fibrinogen beta chain increases expression ISO chromium nitrate results in increased expression of FGB protein CTD PMID:23618972 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO chromium nitrate results in increased expression of FGG protein CTD PMID:23618972 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fkrp fukutin related protein increases expression ISO chromium nitrate results in increased expression of FKRP protein CTD PMID:23618972 NCBI chr 1:77,479,641...77,486,954
Ensembl chr 1:77,476,084...77,486,992
JBrowse link
G Gc GC, vitamin D binding protein decreases expression ISO chromium nitrate results in decreased expression of GC protein CTD PMID:23618972 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO chromium nitrate results in increased expression of GCLC mRNA CTD PMID:20491607 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase increases expression ISO chromium nitrate results in increased expression of HAAO protein CTD PMID:22144121 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression ISO chromium nitrate results in increased expression of HACL1 protein CTD PMID:22144121 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase increases expression ISO chromium nitrate results in increased expression of HIBADH protein CTD PMID:22144121 NCBI chr 4:81,649,180...81,747,244
Ensembl chr 4:81,649,175...81,780,617
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO chromium nitrate results in increased expression of HMOX1 mRNA CTD PMID:20491607 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO chromium nitrate results in increased expression of HSPD1 protein CTD PMID:19771553 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Khk ketohexokinase decreases expression ISO chromium nitrate results in decreased expression of KHK protein CTD PMID:22144121 NCBI chr 6:25,445,298...25,455,834
Ensembl chr 6:25,445,300...25,455,717
JBrowse link
G Kng2 kininogen 2 increases expression ISO chromium nitrate results in increased expression of KNG1 protein CTD PMID:23618972 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Krt10 keratin 10 increases expression ISO chromium nitrate results in increased expression of KRT10 protein CTD PMID:19771553 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krt16 keratin 16 increases expression ISO chromium nitrate results in increased expression of KRT16 protein CTD PMID:19771553 NCBI chr10:85,168,357...85,171,744
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt17 keratin 17 increases expression ISO chromium nitrate results in increased expression of KRT17 protein CTD PMID:19771553 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt18 keratin 18 decreases expression ISO chromium nitrate results in decreased expression of KRT18 protein CTD PMID:22144121 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt25 keratin 25 increases expression ISO chromium nitrate results in increased expression of KRT25 protein CTD PMID:19771553 NCBI chr10:84,267,600...84,276,312
Ensembl chr10:84,267,399...84,274,965
JBrowse link
G Krt27 keratin 27 increases expression ISO chromium nitrate results in increased expression of KRT27 protein CTD PMID:19771553 NCBI chr10:84,298,684...84,303,967
Ensembl chr10:84,298,508...84,303,967
JBrowse link
G Mdh1 malate dehydrogenase 1 increases expression ISO chromium nitrate results in increased expression of MDH1 protein CTD PMID:22144121 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mt2A metallothionein 2A increases expression ISO chromium nitrate results in increased expression of MT2A mRNA CTD PMID:20491607 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO chromium nitrate results in increased expression of PARK7 protein CTD PMID:22144121 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pcca propionyl-CoA carboxylase subunit alpha increases expression ISO chromium nitrate results in increased expression of PCCA protein CTD PMID:22144121 NCBI chr15:99,627,955...99,969,555
Ensembl chr15:99,627,982...99,968,266
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression ISO chromium nitrate results in decreased expression of PDHB protein CTD PMID:22144121 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Phb1 prohibitin 1 decreases expression ISO chromium nitrate results in decreased expression of PHB protein CTD PMID:22144121 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Rgn regucalcin decreases expression ISO chromium nitrate results in decreased expression of RGN protein CTD PMID:22144121 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 decreases expression ISO chromium nitrate results in decreased expression of RPLP0 protein CTD PMID:22144121 NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632
JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO chromium nitrate results in decreased expression of SERPINC1 protein CTD PMID:23618972 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta decreases expression ISO chromium nitrate results in decreased expression of SUCLG2 protein CTD PMID:22144121 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
JBrowse link
G Tkfc triokinase and FMN cyclase increases expression ISO chromium nitrate results in increased expression of TKFC protein CTD PMID:22144121 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression ISO chromium nitrate results in decreased expression of UQCRC1 protein CTD PMID:22144121 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link
G Vcp valosin-containing protein decreases expression ISO chromium nitrate results in decreased expression of VCP protein CTD PMID:22144121 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
ferbam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100125598 metallothionein 1a pseudogene increases expression ISO ferbam results in increased expression of MT1G mRNA CTD PMID:32870474 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO ferbam results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
ferric ammonium citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 increases activity
decreases activity
ISO ferric ammonium citrate results in increased activity of ACO1 protein
ferric ammonium citrate results in decreased activity of ACO1 protein
CTD PMID:11054110 PMID:18073202 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 multiple interactions
increases activity
ISO ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]; ferric ammonium citrate inhibits the reaction [Manganese results in decreased activity of ACO2 protein]
ferric ammonium citrate results in increased activity of ACO2 protein
CTD PMID:16625280 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:32283200 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of ALB protein] CTD PMID:24862973 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Anxa3 annexin A3 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ANXA3 protein] CTD PMID:19515424 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ARHGDIA protein] CTD PMID:19515424 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO ferric ammonium citrate results in increased cleavage of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]
CTD PMID:17191120 PMID:26318285 PMID:27481217 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] CTD PMID:12807743 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO ferric ammonium citrate results in decreased expression of COL1A1 mRNA CTD PMID:19735707 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases phosphorylation
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; acetylleucyl-leucyl-norleucinal inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Cyclosporine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Deferoxamine inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; DNM1L protein mutant form inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein]; ferric ammonium citrate results in decreased phosphorylation of and affects the localization of DNM1L protein; N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]; Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:26318285 PMID:27481217 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:32283200 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Erp29 endoplasmic reticulum protein 29 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of ERP29 protein] CTD PMID:19515424 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G F3 coagulation factor III, tissue factor increases expression
multiple interactions
ISO ferric ammonium citrate results in increased expression of F3 mRNA
Deferoxamine inhibits the reaction [ferric ammonium citrate results in increased expression of F3 mRNA]
CTD PMID:25858758 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO ferric ammonium citrate promotes the reaction [Palmitic Acid results in increased expression of FTH1 protein] CTD PMID:32283200 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
increases expression
ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of FTL mRNA
ferric ammonium citrate results in increased expression of FTL1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:12393473 PMID:19913091 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein] CTD PMID:19515424 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GLO1 protein] CTD PMID:19515424 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases expression
ISO Deferoxamine promotes the reaction [ferric ammonium citrate results in decreased expression of HAMP mRNA]; ferric ammonium citrate affects the reaction [Deferoxamine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]]; ferric ammonium citrate inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of HMOX1 protein
[ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HMOX1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein]
CTD PMID:12393473 PMID:16439612 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPA1A protein] CTD PMID:19515424
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA1L mRNA CTD PMID:12393473 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of HSPA9 mRNA CTD PMID:12393473 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of HSPD1 protein] CTD PMID:19515424 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL1B protein] CTD PMID:24862973 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of IL6 mRNA]; ferric ammonium citrate inhibits the reaction [Ozone results in increased secretion of IL6 protein] CTD PMID:24862973 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]; Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] CTD PMID:32283200 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases expression
decreases activity
EXP
ISO
ferric ammonium citrate results in decreased expression of IREB2 protein
ferric ammonium citrate results in decreased activity of IREB2 protein
CTD PMID:11054110 PMID:17469137 PMID:18073202 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [bathophenanthroline disulfonic acid results in decreased expression of LCN2 protein] CTD PMID:17350462 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK1 protein
ferric ammonium citrate results in increased phosphorylation of MAPK1 protein
CTD PMID:17191120 PMID:25858758 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO ferric ammonium citrate results in increased phosphorylation of MAPK14 protein CTD PMID:17191120 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in decreased phosphorylation of MAPK3 protein
ferric ammonium citrate results in increased phosphorylation of MAPK3 protein
CTD PMID:17191120 PMID:25858758 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of MRPS9 protein] CTD PMID:19515424 NCBI chr 9:45,113,554...45,172,375
Ensembl chr 9:45,113,554...45,172,375
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA CTD PMID:12393473 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of NCOA4 protein] CTD PMID:32283200 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,556
Ensembl chr16:7,366,542...7,409,556
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA] CTD PMID:9826428 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Oga O-GlcNAcase multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of OGA protein] CTD PMID:24862973 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of P4HA1 protein] CTD PMID:19515424 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PDHB protein] CTD PMID:19515424 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PGK1 protein] CTD PMID:19515424 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions ISO [ferric ammonium citrate results in increased abundance of Iron] which results in increased expression of PMP22 mRNA CTD PMID:12393473 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of PPIA protein] CTD PMID:19515424 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of PTGS2 mRNA] CTD PMID:24862973 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of RACK1 protein] CTD PMID:19515424 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression ISO ferric ammonium citrate results in increased expression of SLC11A1 mRNA CTD PMID:11054110 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression ISO ferric ammonium citrate results in increased expression of SLC11A2 mRNA CTD PMID:11054110 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression
multiple interactions
EXP
ISO
ferric ammonium citrate results in increased expression of SLC40A1 mRNA
SLC40A1 protein inhibits the reaction [ferric ammonium citrate results in increased expression of FTL1 mRNA]
CTD PMID:19913091 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of SOD1 mRNA] CTD PMID:24862973 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tf transferrin multiple interactions ISO ferric ammonium citrate inhibits the reaction [TF protein results in increased uptake of Iron] CTD PMID:11335103 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfr2 transferrin receptor 2 decreases expression ISO ferric ammonium citrate results in decreased expression of TFR2 protein CTD PMID:25633564 NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO ferric ammonium citrate results in decreased expression of TFRC mRNA; ferric ammonium citrate results in decreased expression of TFRC protein
[ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of TFRC mRNA
CTD PMID:11054110 PMID:12393473 PMID:16760464 PMID:18073202 PMID:25633564 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ferric ammonium citrate inhibits the reaction [Ozone results in increased expression of TNF protein] CTD PMID:24862973 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpd52l1 TPD52 like 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of TPD52L1 protein] CTD PMID:19515424 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109
JBrowse link
G Vdac2 voltage-dependent anion channel 2 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of VDAC2 protein] CTD PMID:19515424 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO ferric ammonium citrate inhibits the reaction [Palmitic Acid results in increased expression of XBP1 protein] CTD PMID:32283200 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
iron(3+) sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 multiple interactions ISO ferric sulfate inhibits the reaction [Nickel results in increased activity of ACO1 protein] CTD PMID:16877034 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases activity
EXP Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; Curcumin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein] CTD PMID:16956363 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
EXP Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GPT protein]; Curcumin inhibits the reaction [ferric sulfate results in increased activity of GPT protein] CTD PMID:16956363 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ferric sulfate inhibits the reaction [Nickel results in increased stability of HIF1A protein] CTD PMID:16877034 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
iron(III) citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases secretion
multiple interactions
increases expression
ISO ferric citrate results in increased secretion of ALB protein
Alcohols inhibits the reaction [ferric citrate results in increased expression of ALB mRNA]; Alcohols inhibits the reaction [ferric citrate results in increased secretion of ALB protein]; ferric citrate inhibits the reaction [Alcohols results in increased expression of ALB mRNA]; ferric citrate inhibits the reaction [Alcohols results in increased secretion of ALB protein]
CTD PMID:24025710 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression
multiple interactions
ISO ferric citrate results in increased expression of ALDOB mRNA
Alcohols inhibits the reaction [ferric citrate results in increased expression of ALDOB mRNA]; ferric citrate inhibits the reaction [Alcohols results in increased expression of ALDOB mRNA]
CTD PMID:24025710 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO ferric citrate results in decreased expression of AQP4 mRNA CTD PMID:29959986 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Ca9 carbonic anhydrase 9 decreases expression ISO ferric citrate results in decreased expression of CA9 mRNA CTD PMID:29959986 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO ferric citrate results in decreased expression of CCL2 mRNA CTD PMID:29959986 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cftr CF transmembrane conductance regulator decreases expression ISO ferric citrate results in decreased expression of CFTR mRNA CTD PMID:29959986 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Crp C-reactive protein increases expression ISO ferric citrate results in increased expression of CRP mRNA CTD PMID:29959986 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
ISO Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA]; ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA] CTD PMID:24025710 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO ferric citrate results in increased expression of CYP3A4 mRNA; ferric citrate results in increased expression of CYP3A4 protein
Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP3A4 mRNA]; Alcohols promotes the reaction [ferric citrate results in increased expression of CYP3A4 protein]; ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP3A4 mRNA]; ferric citrate promotes the reaction [Alcohols results in increased expression of CYP3A4 protein]
CTD PMID:24025710 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [trigonelline co-treated with ferric citrate] results in increased expression of DDIT3 mRNA CTD PMID:29959986 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Edn1 endothelin 1 decreases expression ISO ferric citrate results in decreased expression of EDN1 mRNA CTD PMID:29959986 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Epo erythropoietin increases expression ISO ferric citrate results in increased expression of EPO mRNA CTD PMID:29959986 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G F10 coagulation factor X decreases activity ISO ferric citrate results in decreased activity of F10 protein CTD PMID:6421970 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F2 coagulation factor II decreases activity ISO ferric citrate results in decreased activity of F2 protein CTD PMID:6421970 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression
multiple interactions
ISO ferric citrate results in increased expression of FTH1 mRNA
[trigonelline co-treated with ferric citrate] results in increased expression of FTH1 mRNA
CTD PMID:29959986 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO [trigonelline co-treated with ferric citrate] results in increased expression of FTL mRNA CTD PMID:29959986 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO ferric citrate results in increased expression of GCLM mRNA CTD PMID:29959986 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]
ferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]; ferric citrate inhibits the reaction [Quercetin results in increased expression of HIF1A mRNA]; ferric citrate inhibits the reaction [Quercetin results in increased expression of HIF1A protein]
CTD PMID:16527254 PMID:17015263 PMID:17364964 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO ferric citrate results in increased expression of HMOX1 mRNA CTD PMID:29959986 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO ferric citrate results in decreased expression of IL1A mRNA CTD PMID:29959986 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [trigonelline co-treated with ferric citrate] results in decreased expression of KEAP1 mRNA CTD PMID:29959986 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Klk1 kallikrein 1 decreases activity ISO ferric citrate results in decreased activity of KLK1 protein CTD PMID:6421970 NCBI chr 1:94,642,722...94,646,714
Ensembl chr 1:94,642,687...94,646,754
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
ISO ferric citrate affects the localization of NFE2L2 protein
trigonelline inhibits the reaction [ferric citrate affects the localization of NFE2L2 protein]
CTD PMID:29959986 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO ferric citrate results in increased expression of NQO1 mRNA; ferric citrate results in increased expression of NQO1 protein
trigonelline inhibits the reaction [ferric citrate results in increased expression of NQO1 protein]
CTD PMID:29959986 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO ferric citrate inhibits the reaction [Deferoxamine results in increased expression of PTGS2 protein] CTD PMID:16527254 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO ferric citrate results in decreased expression of SERPINE1 mRNA CTD PMID:29959986 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO ferric citrate results in increased expression of SQSTM1 mRNA CTD PMID:29959986 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tf transferrin increases expression ISO ferric citrate results in increased expression of TF mRNA CTD PMID:24025710 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfrc transferrin receptor increases expression
multiple interactions
ISO ferric citrate results in increased expression of TFRC protein
ferric citrate inhibits the reaction [Quercetin results in increased expression of TFRC protein]
CTD PMID:17364964 PMID:29959986 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO ferric citrate results in decreased expression of TNF mRNA CTD PMID:29959986 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO ferric citrate results in increased expression of TXNRD1 mRNA CTD PMID:29959986 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
iron(III) nitrilotriacetate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased expression of ABCB1 protein]; ferric nitrilotriacetate inhibits the reaction [Razoxane results in increased expression of ABCB1 protein] CTD PMID:18385176 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO ferric nitrilotriacetate results in increased expression of ABCC1 mRNA CTD PMID:18617210 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO ferric nitrilotriacetate results in increased expression of ABCC2 mRNA CTD PMID:18617210 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO ferric nitrilotriacetate results in increased expression of ABCC4 mRNA CTD PMID:18617210 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Anxa2 annexin A2 increases expression EXP ferric nitrilotriacetate results in increased expression of ANXA2 mRNA CTD PMID:10854235 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP ferric nitrilotriacetate results in increased expression of BAX mRNA CTD PMID:23208426 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression EXP ferric nitrilotriacetate results in increased expression of BBC3 mRNA CTD PMID:23208426 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bik BCL2-interacting killer increases expression EXP ferric nitrilotriacetate results in increased expression of BIK mRNA CTD PMID:23208426 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296
JBrowse link
G Cald1 caldesmon 1 increases expression EXP ferric nitrilotriacetate results in increased expression of CALD1 mRNA CTD PMID:10854235 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Canx calnexin increases expression EXP ferric nitrilotriacetate results in increased expression of CANX protein CTD PMID:16908007 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Casp12 caspase 12 increases expression EXP ferric nitrilotriacetate results in increased expression of CASP12 mRNA CTD PMID:23208426 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA] CTD PMID:21907755 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions EXP [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA] CTD PMID:21907755 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA] CTD PMID:21907755 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of CAT protein; chrysin inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of CAT protein]; Quercetin inhibits the reaction [ferric nitrilotriacetate results in decreased activity of CAT protein] CTD PMID:9667754 PMID:15198074 PMID:18684806 PMID:21907755 PMID:23194824 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP ferric nitrilotriacetate results in increased expression of CCND1 mRNA; ferric nitrilotriacetate results in increased expression of CCND1 protein CTD PMID:18055543 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP ferric nitrilotriacetate results in increased expression of CD44 mRNA; ferric nitrilotriacetate results in increased expression of CD44 protein CTD PMID:18055543 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd47 Cd47 molecule increases expression EXP ferric nitrilotriacetate results in increased expression of CD47 mRNA CTD PMID:9119739 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP ferric nitrilotriacetate results in increased expression of CDKN1A mRNA CTD PMID:23208426 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP ferric nitrilotriacetate results in decreased expression of CHRM1 mRNA CTD PMID:19490752 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP ferric nitrilotriacetate results in decreased expression of CHRM2 mRNA CTD PMID:19490752 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
EXP ferric nitrilotriacetate results in increased expression of COL1A1 protein
ethylisopropylamiloride inhibits the reaction [ferric nitrilotriacetate results in increased expression of COL1A1 protein]
CTD PMID:11159895 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cygb cytoglobin multiple interactions EXP CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA]; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA]; CYGB protein results in decreased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid] CTD PMID:16581302 NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein; [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein; [Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]] CTD PMID:12086689 PMID:17034788 PMID:21352821 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO ferric nitrilotriacetate results in increased expression of FOS mRNA CTD PMID:10381381 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP ferric nitrilotriacetate results in increased expression of FOSL1 mRNA; ferric nitrilotriacetate results in increased expression of FOSL1 protein CTD PMID:18055543 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP ferric nitrilotriacetate results in decreased activity of G6PD protein CTD PMID:9667754 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO ferric nitrilotriacetate results in increased expression of GCLC mRNA CTD PMID:18617210 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
EXP ferric nitrilotriacetate results in decreased activity of GSR protein
[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of GSR protein; Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of GSR protein]; Quercetin inhibits the reaction [ferric nitrilotriacetate results in decreased activity of GSR protein]
CTD PMID:9667754 PMID:15198074 PMID:30098279 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression EXP ferric nitrilotriacetate results in increased expression of GTSE1 mRNA CTD PMID:23208426 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased secretion of HAVCR1 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of HAVCR1 protein]; Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased secretion of HAVCR1 protein] CTD PMID:21907755 PMID:30098279 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased activity of HIF1A protein]; ferric nitrilotriacetate inhibits the reaction [Razoxane results in increased activity of HIF1A protein] CTD PMID:18385176 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP
ISO
ferric nitrilotriacetate results in increased expression of HMOX1 mRNA CTD PMID:18617210 PMID:19490752 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP ferric nitrilotriacetate results in increased expression of HSP90AA1 mRNA CTD PMID:10854235 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Il24 interleukin 24 increases expression EXP ferric nitrilotriacetate results in increased expression of IL24 mRNA CTD PMID:23208426 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
ferric nitrilotriacetate results in increased expression of IL6 protein
ferric nitrilotriacetate results in increased expression of IL6 mRNA
[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of IL6 protein; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of IL6 protein]
CTD PMID:15781289 PMID:19490752 PMID:23194824 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP ferric nitrilotriacetate results in increased expression of JUN mRNA; ferric nitrilotriacetate results in increased expression of JUN protein CTD PMID:18055543 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Krt18 keratin 18 multiple interactions ISO [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein CTD PMID:17034788 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 multiple interactions ISO [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein CTD PMID:17034788 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression EXP ferric nitrilotriacetate results in increased expression of MCM3 mRNA CTD PMID:23208426 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [ferric nitrilotriacetate co-treated with Hydrogen Peroxide] inhibits the reaction [MT1 protein binds to Cadmium]; [ferric nitrilotriacetate co-treated with Hydrogen Peroxide] inhibits the reaction [MT1 protein binds to Zinc]; ferric nitrilotriacetate results in increased oxidation of [MT1 protein binds to Zinc] CTD PMID:22001350 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [ferric nitrilotriacetate co-treated with Hydrogen Peroxide] inhibits the reaction [MT2 protein binds to Cadmium] CTD PMID:22001350 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mt3 metallothionein 3 decreases response to substance ISO MT3 protein results in decreased susceptibility to ferric nitrilotriacetate CTD PMID:12383939 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP ferric nitrilotriacetate results in increased expression of MYC mRNA; ferric nitrilotriacetate results in increased expression of MYC protein CTD PMID:18055543 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization ISO ferric nitrilotriacetate affects the localization of NFE2L2 protein CTD PMID:18617210 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of NFKB1 mRNA] CTD PMID:21907755 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO
EXP
ferric nitrilotriacetate inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; ferric nitrilotriacetate inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]; ferric nitrilotriacetate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
ferric nitrilotriacetate results in increased expression of NOS2 protein
[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of NOS2 protein; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of NOS2 protein]; chrysin inhibits the reaction [ferric nitrilotriacetate results in increased expression of NOS2 protein]; ferric nitrilotriacetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; ferric nitrilotriacetate promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
CTD PMID:11461780 PMID:11746204 PMID:12490132 PMID:23194824 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO ferric nitrilotriacetate results in increased expression of NQO1 mRNA; ferric nitrilotriacetate results in increased expression of NQO1 protein CTD PMID:18617210 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
EXP [ferric nitrilotriacetate results in increased abundance of Hydroxyl Radical] which results in increased activity of ODC1 protein; Active Hexose Correlated Compound inhibits the reaction [[ferric nitrilotriacetate results in increased abundance of Hydroxyl Radical] which results in increased activity of ODC1 protein]; Vitamin E inhibits the reaction [ferric nitrilotriacetate results in increased activity of ODC1 protein] CTD PMID:9667754 PMID:14623030 PMID:15949125 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression EXP ferric nitrilotriacetate results in increased expression of PCK1 mRNA CTD PMID:16960379 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of PCNA protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of PCNA protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein] CTD PMID:21907755 PMID:23194824 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP ferric nitrilotriacetate results in increased expression of PHLDA3 mRNA CTD PMID:23208426 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
increases expression
increases activity
ISO Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased activity of PLAU mRNA]; Deferoxamine inhibits the reaction [ferric nitrilotriacetate results in increased expression of PLAU mRNA] CTD PMID:17571974 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plk2 polo-like kinase 2 increases expression EXP ferric nitrilotriacetate results in increased expression of PLK2 mRNA CTD PMID:23208426 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit increases expression EXP ferric nitrilotriacetate results in increased expression of POLA1 mRNA CTD PMID:10854235 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP ferric nitrilotriacetate results in increased expression of PPIA protein CTD PMID:16908007 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of PTGS2 protein; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of PTGS2 protein]; chrysin inhibits the reaction [ferric nitrilotriacetate results in increased expression of PTGS2 protein]; Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of PTGS2 protein] CTD PMID:23194824 PMID:30098279 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B decreases expression EXP ferric nitrilotriacetate results in decreased expression of PTPRB mRNA CTD PMID:10854235 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 increases expression EXP ferric nitrilotriacetate results in increased expression of PTPRZ1 mRNA; ferric nitrilotriacetate results in increased expression of PTPRZ1 protein CTD PMID:18055543 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased localization of RELA protein; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased localization of RELA protein] CTD PMID:23194824 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rpl19 ribosomal protein L19 increases expression EXP ferric nitrilotriacetate results in increased expression of RPL19 mRNA CTD PMID:10854235 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog increases expression EXP ferric nitrilotriacetate results in increased expression of RPRM mRNA CTD PMID:23208426 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998
JBrowse link
G Rps13 ribosomal protein S13 increases expression EXP ferric nitrilotriacetate results in increased expression of RPS13 mRNA CTD PMID:10854235 NCBI chr 1:170,572,925...170,575,355
Ensembl chr 1:170,572,921...170,575,355
JBrowse link
G Rps15 ribosomal protein S15 increases expression EXP ferric nitrilotriacetate results in increased expression of RPS15 mRNA CTD PMID:10854235 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression ISO ferric nitrilotriacetate results in decreased expression of SLC11A2 mRNA CTD PMID:11925462 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression ISO ferric nitrilotriacetate results in decreased expression of SLC40A1 mRNA CTD PMID:11925462 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP ferric nitrilotriacetate inhibits the reaction [Dimethylnitrosamine results in decreased expression of SOD1 protein] CTD PMID:15842777 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Ssrp1 structure specific recognition protein 1 increases expression EXP ferric nitrilotriacetate results in increased expression of SSRP1 mRNA CTD PMID:8844983 NCBI chr 3:70,124,371...70,134,481
Ensembl chr 3:70,118,655...70,134,482
JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP ferric nitrilotriacetate results in increased expression of TGFA mRNA; ferric nitrilotriacetate results in increased expression of TGFA protein CTD PMID:8340253 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA] CTD PMID:16581302 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP ferric nitrilotriacetate results in increased expression of TGFB2 mRNA CTD PMID:23208426 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] CTD PMID:16581302 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO
EXP
ferric nitrilotriacetate results in increased expression of TNF protein
[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of TNF protein; chrysin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in increased expression of TNF protein]
CTD PMID:15781289 PMID:23194824 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 mRNA]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in increased expression of TP53 protein] CTD PMID:21907755 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txn1 thioredoxin 1 increases expression EXP ferric nitrilotriacetate results in increased expression of TXN protein CTD PMID:15834431 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnip thioredoxin interacting protein decreases expression
increases methylation
EXP ferric nitrilotriacetate results in decreased expression of TXNIP protein
ferric nitrilotriacetate results in increased methylation of TXNIP promoter
CTD PMID:15834431 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ubd ubiquitin D increases expression EXP ferric nitrilotriacetate results in increased expression of UBD mRNA CTD PMID:23208426 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,383,424...1,389,406
Ensembl chr20:1,383,424...1,389,406
JBrowse link
nickel ferrite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO nickel ferrite analog results in increased expression of BAX mRNA; nickel ferrite results in increased expression of BAX mRNA CTD PMID:21382431 PMID:25966046 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO nickel ferrite analog results in decreased expression of BCL2 mRNA; nickel ferrite results in decreased expression of BCL2 mRNA CTD PMID:21382431 PMID:25966046 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO nickel ferrite results in decreased expression of BIRC5 mRNA CTD PMID:21382431 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO nickel ferrite analog results in increased activity of CASP3 protein; nickel ferrite results in increased activity of CASP3 protein
nickel ferrite analog results in increased expression of CASP3 mRNA; nickel ferrite results in increased expression of CASP3 mRNA
CTD PMID:21382431 PMID:25966046 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity
increases expression
ISO nickel ferrite analog results in increased activity of CASP9 protein; nickel ferrite results in increased activity of CASP9 protein
nickel ferrite analog results in increased expression of CASP9 mRNA; nickel ferrite results in increased expression of CASP9 mRNA
CTD PMID:21382431 PMID:25966046 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Tp53 tumor protein p53 increases expression ISO nickel ferrite analog results in increased expression of TP53 mRNA; nickel ferrite results in increased expression of TP53 mRNA CTD PMID:21382431 PMID:25966046 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    chemical entity 20049
      molecular entity 20047
        inorganic molecular entity 19754
          inorganic ion 16042
            inorganic cation 15630
              trivalent inorganic cation 180
                hexaamminecobalt(3+) + 0
                hexaammineiridium(3+) 0
                monoatomic trication + 180
paths to the root