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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phosphagen
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Accession:CHEBI:64618 term browser browse the term
Definition:Any of a group of guanidine or amidine phosphates that function as storage depots for high-energy phosphate in muscle with the purpose of regenerating ATP from ADP during muscular contraction.
Synonyms:xref: Wikipedia:Phosphagen



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N-phosphocreatine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]]; Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein] CTD PMID:37648050 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP
ISO
Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]
CTD PMID:34358621 PMID:34455488 PMID:37648050 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
CTD PMID:34455488 PMID:37648050 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
7-oxozeanol inhibits the reaction [Phosphocreatine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of CASP3 protein modified form]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 protein]
CTD PMID:34358621 PMID:34455488 PMID:37648050 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased expression of CASP9 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]
Phosphocreatine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP9 protein]
CTD PMID:34455488 PMID:37648050 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of CYCS protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein] CTD PMID:34455488 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 protein] CTD PMID:34358621 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] CTD PMID:34455488 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Ins1 insulin 1 multiple interactions EXP Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased secretion of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:34455488 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of IRS1 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein] CTD PMID:34455488 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP Phosphocreatine inhibits the reaction [Dietary Fats results in decreased activity of LPL protein] CTD PMID:37648050 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions EXP 7-oxozeanol inhibits the reaction [Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MAP3K7 protein]]; Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of MAP3K7 protein]; Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of MAP3K7 protein] CTD PMID:34358621 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein] CTD PMID:34358621 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions EXP Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of PPID protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased expression of PPID protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein] CTD PMID:34455488 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in increased expression of RIPK3 protein] CTD PMID:34358621 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP Phosphocreatine inhibits the reaction [Doxorubicin results in decreased expression of SOD3 protein] CTD PMID:34358621 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases response to substance
multiple interactions
EXP STAT3 protein results in increased susceptibility to Phosphocreatine
Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]
CTD PMID:34455488 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    chemical entity 19840
      atom 19809
        nonmetal atom 19747
          nitrogen atom 18962
            nitrogen molecular entity 18934
              phosphagen 17
                N(omega)-phospho-L-arginine 0
                N-phosphocreatine 17
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      chalcogen 19515
                        oxygen atom 19520
                          oxygen molecular entity 19490
                            hydroxides 19300
                              oxoacid 18725
                                pnictogen oxoacid 13221
                                  phosphorus oxoacid 12413
                                    phosphoric acids 11427
                                      phosphoric acid 11417
                                        phosphoric acid derivative 11226
                                          phosphate 11225
                                            organic phosphate 11225
                                              phosphagen 17
                                                N(omega)-phospho-L-arginine 0
                                                N-phosphocreatine 17
paths to the root