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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:uremic toxin
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Accession:CHEBI:64584 term browser browse the term
Definition:A toxin that accumulates in patients with chronic kidney disease.
Synonyms:related_synonym: uremic toxins
 xref: Wikipedia:Uremic_toxin


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N-benzoylglycine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO hippuric acid promotes the reaction [ABCC3 protein results in increased uptake of Taurocholic Acid] CTD PMID:30639138 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO hippuric acid inhibits the reaction [ABCC4 protein results in increased export of Methotrexate] CTD PMID:21483698 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO hippuric acid inhibits the reaction [ABCG2 protein results in increased export of estrone sulfate] CTD PMID:21483698 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of hippuric acid CTD PMID:24709313 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO hippuric acid results in increased expression of SLC10A1 mRNA CTD PMID:30639138 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
p-cresol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO 4-cresol binds to ALB protein CTD PMID:11334365 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Becn1 beclin 1 increases expression ISO
EXP
4-cresol results in increased expression of BECN1 protein CTD PMID:25668154 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Casp3 caspase 3 increases activity ISO 4-cresol results in increased activity of CASP3 protein CTD PMID:25668154 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO SQSTM1 mutant form inhibits the reaction [4-cresol results in increased cleavage of CASP8 protein] CTD PMID:25668154 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cdh2 cadherin 2 multiple interactions
affects localization
EXP 4-cresol inhibits the reaction [CTNND1 protein binds to CDH2 protein]; Go 6976 inhibits the reaction [4-cresol affects the localization of CDH2 protein]; Go 6976 inhibits the reaction [4-cresol inhibits the reaction [CTNND1 protein binds to CDH2 protein]] CTD PMID:23466501 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions EXP 4-cresol affects the localization of and results in decreased phosphorylation of CTNND1 protein; 4-cresol inhibits the reaction [CTNND1 protein binds to CDH2 protein]; Go 6976 inhibits the reaction [4-cresol affects the localization of and results in decreased phosphorylation of CTNND1 protein]; Go 6976 inhibits the reaction [4-cresol inhibits the reaction [CTNND1 protein binds to CDH2 protein]]; PRKCA mutant form inhibits the reaction [4-cresol affects the localization of and results in decreased phosphorylation of CTNND1 protein] CTD PMID:23466501 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO 4-cresol inhibits the reaction [IL1B protein results in increased expression of CX3CL1 protein] CTD PMID:16954166 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing ISO CYP1A2 protein results in increased metabolism of 4-cresol CTD PMID:16174805 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of 4-cresol CTD PMID:16174805 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of 4-cresol CTD PMID:16174805 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G F11r F11 receptor decreases expression ISO 4-cresol results in decreased expression of F11R protein CTD PMID:16954166 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
decreases phosphorylation
EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [4-cresol results in decreased phosphorylation of GJA1 protein]; PRKCA mutant form inhibits the reaction [4-cresol results in decreased phosphorylation of GJA1 protein] CTD PMID:22813906 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 4-cresol results in increased expression of HMOX1 mRNA CTD PMID:29214717 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 4-cresol inhibits the reaction [IL1B protein results in increased expression of ICAM1 mRNA]; 4-cresol inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; 4-cresol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; 4-cresol inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12427124 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 4-cresol inhibits the reaction [IL1B protein results in increased expression of CX3CL1 protein]; 4-cresol inhibits the reaction [IL1B protein results in increased expression of ICAM1 mRNA]; 4-cresol inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; 4-cresol inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; 4-cresol inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein] CTD PMID:12427124 PMID:16954166 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO 4-cresol results in increased phosphorylation of JUN protein CTD PMID:25668154 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mir139 microRNA 139 increases expression ISO 4-cresol results in increased expression of MIR139 mRNA CTD PMID:32105654 NCBI chr 1:166,589,545...166,589,612
Ensembl chr 1:166,589,545...166,589,612
JBrowse link
G Mir144 microRNA 144 decreases expression ISO 4-cresol results in decreased expression of MIR144 mRNA CTD PMID:32105654 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir186 microRNA 186 increases expression ISO 4-cresol results in increased expression of MIR186 mRNA CTD PMID:32105654 NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
JBrowse link
G Mir188 microRNA 188 increases expression ISO 4-cresol results in increased expression of MIR188 mRNA CTD PMID:32105654 NCBI chr  X:16,110,270...16,110,349
Ensembl chr  X:16,110,270...16,110,349
JBrowse link
G Mir190b microRNA 190b increases expression ISO 4-cresol results in increased expression of MIR190B mRNA CTD PMID:32105654 NCBI chr 2:189,421,137...189,421,214
Ensembl chr 2:189,421,137...189,421,214
JBrowse link
G Mir196b microRNA 196b decreases expression ISO 4-cresol results in decreased expression of MIR196B mRNA CTD PMID:32105654 NCBI chr 4:82,199,056...82,199,140
Ensembl chr 4:82,199,056...82,199,140
JBrowse link
G Mir196c microRNA 196c decreases expression ISO 4-cresol results in decreased expression of MIR196A-1 mRNA CTD PMID:32105654 NCBI chr10:84,113,578...84,113,657
Ensembl chr10:84,113,578...84,113,657
JBrowse link
G Mir200b microRNA 200b decreases expression ISO 4-cresol results in decreased expression of MIR200B mRNA CTD PMID:32105654 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir204 microRNA 204 increases expression ISO 4-cresol results in increased expression of MIR204 mRNA CTD PMID:32105654 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir20a microRNA 20a increases expression ISO 4-cresol results in increased expression of MIR20A mRNA CTD PMID:32105654 NCBI chr15:100,180,334...100,180,418
Ensembl chr15:100,180,334...100,180,418
JBrowse link
G Mir324 microRNA 324 increases expression ISO 4-cresol results in increased expression of MIR324 mRNA CTD PMID:32105654 NCBI chr10:56,621,126...56,621,208
Ensembl chr10:56,621,124...56,621,212
JBrowse link
G Mir331 microRNA 331 increases expression ISO 4-cresol results in increased expression of MIR331 mRNA CTD PMID:32105654 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir410 microRNA 410 increases expression ISO 4-cresol results in increased expression of MIR410 mRNA CTD PMID:32105654 NCBI chr 6:133,893,997...133,894,072
Ensembl chr 6:133,893,993...133,894,073
JBrowse link
G Mir488 microRNA 488 increases expression ISO 4-cresol results in increased expression of MIR488 mRNA CTD PMID:32105654 NCBI chr13:76,198,593...76,198,671
Ensembl chr13:76,198,593...76,198,671
JBrowse link
G Mir494 microRNA 494 increases expression ISO 4-cresol results in increased expression of MIR494 mRNA CTD PMID:32105654 NCBI chr 6:133,864,370...133,864,452
Ensembl chr 6:133,864,369...133,864,453
JBrowse link
G Mir541 microRNA 541 increases expression ISO 4-cresol results in increased expression of MIR541 mRNA CTD PMID:32105654 NCBI chr 6:133,892,655...133,892,744
Ensembl chr 6:133,892,655...133,892,744
JBrowse link
G Mir542 microRNA 542 decreases expression ISO 4-cresol results in decreased expression of MIR542 mRNA CTD PMID:32105654 NCBI chr  X:158,152,146...158,152,224
Ensembl chr  X:158,152,146...158,152,224
JBrowse link
G Mir877 microRNA 877 increases expression ISO 4-cresol results in increased expression of MIR877 mRNA CTD PMID:32105654 NCBI chr20:3,318,872...3,318,956
Ensembl chr20:3,318,872...3,318,956
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity ISO 4-cresol results in increased activity of MMP2 protein CTD PMID:30910523 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO 4-cresol results in increased expression of and results in increased activity of MMP9 protein; Everolimus inhibits the reaction [4-cresol results in increased expression of MMP9 protein]; Y 27632 inhibits the reaction [4-cresol results in increased expression of MMP9 protein] CTD PMID:30910523 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
ISO [Everolimus co-treated with Y 27632] inhibits the reaction [4-cresol results in increased phosphorylation of MTOR protein]; Everolimus inhibits the reaction [4-cresol results in increased phosphorylation of MTOR protein]; Y 27632 inhibits the reaction [4-cresol results in increased phosphorylation of MTOR protein] CTD PMID:30910523 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO 4-cresol results in increased expression of NFE2L2 mRNA CTD PMID:29214717 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-cresol results in increased expression of NQO1 mRNA CTD PMID:29214717 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Prkca protein kinase C, alpha increases phosphorylation
increases response to substance
multiple interactions
EXP 4-cresol results in increased phosphorylation of PRKCA protein
PRKCA protein results in increased susceptibility to 4-cresol
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [4-cresol results in increased phosphorylation of PRKCA protein]; 4-cresol results in increased phosphorylation of and results in increased activity of PRKCA protein; PRKCA mutant form inhibits the reaction [4-cresol affects the localization of and results in decreased phosphorylation of CTNND1 protein]; PRKCA mutant form inhibits the reaction [4-cresol results in decreased phosphorylation of GJA1 protein]
CTD PMID:22813906 PMID:23466501 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Rhoa ras homolog family member A increases expression
multiple interactions
ISO 4-cresol results in increased expression of RHOA protein
[Everolimus co-treated with Y 27632] inhibits the reaction [4-cresol results in increased expression of RHOA protein]; Y 27632 inhibits the reaction [4-cresol results in increased expression of RHOA protein]
CTD PMID:30910523 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression ISO 4-cresol results in decreased expression of MIR3068 mRNA CTD PMID:32105654 NCBI chr 6:111,468,732...111,468,807
Ensembl chr 6:111,468,732...111,468,807
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
ISO SQSTM1 mutant form inhibits the reaction [4-cresol results in increased cleavage of CASP8 protein]
4-cresol results in increased expression of SQSTM1 protein
CTD PMID:25668154 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases metabolic processing EXP SULT1A1 protein results in increased metabolism of 4-cresol CTD PMID:11301044 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4-cresol inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; 4-cresol inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; 4-cresol inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; 4-cresol inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:12427124 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
increases glucuronidation
ISO Acetaminophen inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol]; amentoflavone inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 4-cresol] CTD PMID:32421801 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions
increases glucuronidation
ISO 4-cresol inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide]; [4-cresol inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide]] which results in increased abundance of Mycophenolic Acid; Niflumic Acid inhibits the reaction [UGT1A9 protein results in increased glucuronidation of 4-cresol] CTD PMID:31742356 PMID:32421801 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of 4-cresol CTD PMID:8302279 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO 4-cresol inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; 4-cresol inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; 4-cresol inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; 4-cresol inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:12427124 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
salicyluric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of salicylurate CTD PMID:8831264 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
sivelestat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed decreases activity ISO sivelestat results in decreased activity of ELANE protein CTD PMID:19088179 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
tolterodine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Tolterodine Tartrate results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Tolterodine Tartrate results in decreased expression of AHR mRNA CTD PMID:24316275 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO Tolterodine Tartrate binds to and results in decreased activity of CHRM2 protein CTD PMID:15140916 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions ISO Tolterodine Tartrate binds to and results in decreased activity of CHRM3 protein CTD PMID:15140916 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
affects metabolic processing
multiple interactions
ISO CYP2D6 protein results in increased metabolism of Tolterodine Tartrate
CYP2D6 polymorphism affects the metabolism of Tolterodine Tartrate
Fluoxetine inhibits the reaction [CYP2D6 protein results in increased metabolism of Tolterodine Tartrate]
CTD PMID:10583026 PMID:28087463 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Tolterodine Tartrate results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
decreases expression
ISO Tolterodine Tartrate inhibits the reaction [Dexamethasone results in increased expression of NR3C1 mRNA]
Tolterodine Tartrate results in decreased expression of NR3C1 mRNA
CTD PMID:24316275 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tolterodine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Tolterodine Tartrate results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      biological role 19716
        poison 18120
          toxin 14321
            uremic toxin 62
              (E)-hept-2-enal + 0
              2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid 0
              4-ethylphenyl sulfate 0
              4-ethylphenyl sulfate(1-) 0
              N-benzoylglycine + 6
              methylguanidine + 0
              p-cresol + 56
              p-cresol sulfate 0
              p-cresol sulfate(1-) 0
              salicyluric acid + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      biological role 19716
        biochemical role 19304
          metabolite 19286
            toxin 14321
              uremic toxin 62
                (E)-hept-2-enal + 0
                2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid 0
                4-ethylphenyl sulfate 0
                4-ethylphenyl sulfate(1-) 0
                N-benzoylglycine + 6
                methylguanidine + 0
                p-cresol + 56
                p-cresol sulfate 0
                p-cresol sulfate(1-) 0
                salicyluric acid + 1
paths to the root