CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: lidocaine
Accession: CHEBI:6456
browse the term
Definition: The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Synonyms: exact_synonym: N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
related_synonym: 2-(Diethylamino)-2',6'-acetoxylidide; 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide; Formula=C14H22N2O; InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17); InChIKey=NNJVILVZKWQKPM-UHFFFAOYSA-N; Lidoderm; SMILES=CCN(CC)CC(=O)Nc1c(C)cccc1C; alpha-diethylamino-2,6-dimethylacetanilide
xref: CAS:137-58-6; DrugBank:DB00281; Drug_Central:1579; HMDB:HMDB0014426; KEGG:C07073; KEGG:D00358; LINCS:LSM-3165
xref_mesh: MESH:D008012
xref: PMID:11106996; PMID:11120381; PMID:11431418; PMID:11692349; PMID:15056998; PMID:16668583; PMID:17214917; PMID:18940244; Patent:GB706409; Patent:GB758224; Patent:US2441498; Reaxys:2215784; VSDB:1903; Wikipedia:Lidocaine
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Abca1
ATP binding cassette subfamily A member 1
increases expression
EXP
Lidocaine results in increased expression of ABCA1 mRNA
CTD
PMID:35283115
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abca8
ATP binding cassette subfamily A member 8
decreases expression
EXP
Lidocaine results in decreased expression of ABCA8 mRNA
CTD
PMID:35283115
NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
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Abcb4
ATP binding cassette subfamily B member 4
increases expression
EXP
Lidocaine results in increased expression of ABCB4 mRNA
CTD
PMID:35283115
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Actn3
actinin alpha 3
increases expression
EXP
Lidocaine results in increased expression of ACTN3 mRNA
CTD
PMID:35283115
NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
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Adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
increases expression
EXP
Lidocaine results in increased expression of ADAMTS13 mRNA
CTD
PMID:35283115
NCBI chr 3:10,299,264...10,338,464
Ensembl chr 3:10,300,028...10,346,687
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Adamts15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
decreases expression
EXP
Lidocaine results in decreased expression of ADAMTS15 mRNA
CTD
PMID:35283115
NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
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Adgra2
adhesion G protein-coupled receptor A2
decreases expression
EXP
Lidocaine results in decreased expression of ADGRA2 mRNA
CTD
PMID:35283115
NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483
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Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2
increases expression
EXP
Lidocaine results in increased expression of AGPAT2 mRNA
CTD
PMID:35283115
NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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Akap5
A-kinase anchoring protein 5
decreases expression
EXP
Lidocaine results in decreased expression of AKAP5 mRNA
CTD
PMID:35283115
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Akt1s1
AKT1 substrate 1
multiple interactions
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; dorsomorphin inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]; MK-8722 promotes the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]
CTD
PMID:37914286
NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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Aldh3b1
aldehyde dehydrogenase 3 family, member B1
increases expression
EXP
Lidocaine results in increased expression of ALDH3B1 mRNA
CTD
PMID:35283115
NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
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Alox12
arachidonate 12-lipoxygenase, 12S type
increases expression
EXP
Lidocaine results in increased expression of ALOX12 mRNA
CTD
PMID:35283115
NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
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Alpk1
alpha-kinase 1
increases expression
EXP
Lidocaine results in increased expression of ALPK1 mRNA
CTD
PMID:35283115
NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157
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Amdhd2
amidohydrolase domain containing 2
increases expression
EXP
Lidocaine results in increased expression of AMDHD2 mRNA
CTD
PMID:35283115
NCBI chr10:13,187,579...13,196,148
Ensembl chr10:13,187,578...13,196,095
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Amelx
amelogenin, X-linked
increases expression
EXP
Lidocaine results in increased expression of AMELX mRNA
CTD
PMID:35283115
NCBI chr X:25,076,362...25,087,660
Ensembl chr X:25,076,362...25,087,660
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Ampd1
adenosine monophosphate deaminase 1
increases expression
EXP
Lidocaine results in increased expression of AMPD1 mRNA
CTD
PMID:35283115
NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
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Angpt2
angiopoietin 2
decreases expression
EXP
Lidocaine results in decreased expression of ANGPT2 mRNA
CTD
PMID:35283115
NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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Angpt4
angiopoietin 4
increases expression
EXP
Lidocaine results in increased expression of ANGPT4 mRNA
CTD
PMID:35283115
NCBI chr 3:140,420,389...140,454,213
Ensembl chr 3:140,420,389...140,453,583
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Angptl2
angiopoietin-like 2
increases expression
EXP
Lidocaine results in increased expression of ANGPTL2 mRNA
CTD
PMID:35283115
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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Ankrd33b
ankyrin repeat domain 33B
increases expression
EXP
Lidocaine results in increased expression of ANKRD33B mRNA
CTD
PMID:35283115
NCBI chr 2:82,277,604...82,359,420
Ensembl chr 2:82,283,108...82,358,872
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Anp32a
acidic nuclear phosphoprotein 32 family member A
increases expression
EXP
Lidocaine results in increased expression of ANP32A mRNA
CTD
PMID:35283115
NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443
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Anxa6
annexin A6
increases expression
EXP
Lidocaine results in increased expression of ANXA6 mRNA; Lidocaine results in increased expression of ANXA6 protein
CTD
PMID:27018092
NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
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Aoc3
amine oxidase, copper containing 3
decreases expression
EXP
Lidocaine results in decreased expression of AOC3 mRNA
CTD
PMID:35283115
NCBI chr10:86,272,757...86,280,702
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Apobec1
apolipoprotein B mRNA editing enzyme catalytic subunit 1
increases expression
EXP
Lidocaine results in increased expression of APOBEC1 mRNA
CTD
PMID:35283115
NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390
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Apold1
apolipoprotein L domain containing 1
increases expression
EXP
Lidocaine results in increased expression of APOLD1 mRNA
CTD
PMID:35283115
NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
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Aqp4
aquaporin 4
decreases expression
EXP
Lidocaine results in decreased expression of AQP4 mRNA
CTD
PMID:35283115
NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
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Arhgap11a
Rho GTPase activating protein 11A
increases expression
EXP
Lidocaine results in increased expression of ARHGAP11A mRNA
CTD
PMID:35283115
NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
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Arhgap30
Rho GTPase activating protein 30
decreases expression
EXP
Lidocaine results in decreased expression of ARHGAP30 mRNA
CTD
PMID:35283115
NCBI chr13:83,822,290...83,843,634
Ensembl chr13:83,822,283...83,854,885
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Arhgap45
Rho GTPase activating protein 45
increases expression
EXP
Lidocaine results in increased expression of ARHGAP45 mRNA
CTD
PMID:35283115
NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
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Arhgef3
Rho guanine nucleotide exchange factor 3
decreases expression
EXP
Lidocaine results in decreased expression of ARHGEF3 mRNA
CTD
PMID:35283115
NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
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Arl11
ARF like GTPase 11
increases expression
EXP
Lidocaine results in increased expression of ARL11 mRNA
CTD
PMID:35283115
NCBI chr15:35,483,330...35,485,579
Ensembl chr15:35,480,018...35,496,596
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Aspg
asparaginase
increases expression
EXP
Lidocaine results in increased expression of ASPG mRNA
CTD
PMID:35283115
NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
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Aspm
assembly factor for spindle microtubules
increases expression
EXP
Lidocaine results in increased expression of ASPM mRNA
CTD
PMID:35283115
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
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Aspn
asporin
decreases expression
EXP
Lidocaine results in decreased expression of ASPN mRNA
CTD
PMID:35283115
NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
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Atad2
ATPase family, AAA domain containing 2
increases expression
EXP
Lidocaine results in increased expression of ATAD2 mRNA
CTD
PMID:35283115
NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
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Atad5
ATPase family, AAA domain containing 5
increases expression
EXP
Lidocaine results in increased expression of ATAD5 mRNA
CTD
PMID:35283115
NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
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Atp2c1
ATPase secretory pathway Ca2+ transporting 1
increases expression
EXP
Lidocaine results in increased expression of ATP2C1 mRNA
CTD
PMID:35283115
NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006
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Atp6v0d2
ATPase H+ transporting V0 subunit D2
increases expression
EXP
Lidocaine results in increased expression of ATP6V0D2 mRNA
CTD
PMID:35283115
NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
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Atp8b4
ATPase phospholipid transporting 8B4 (putative)
increases expression
EXP
Lidocaine results in increased expression of ATP8B4 mRNA
CTD
PMID:35283115
NCBI chr 3:113,554,979...113,757,635
Ensembl chr 3:113,556,192...113,757,225
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Aunip
aurora kinase A and ninein interacting protein
increases expression
EXP
Lidocaine results in increased expression of AUNIP mRNA
CTD
PMID:35283115
NCBI chr 5:146,722,329...146,734,924
Ensembl chr 5:146,722,337...146,736,501
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Baat
bile acid CoA:amino acid N-acyltransferase
increases expression
EXP
Lidocaine results in increased expression of BAAT mRNA
CTD
PMID:35283115
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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Bcl2l2
Bcl2-like 2
decreases expression
EXP
Lidocaine results in decreased expression of BCL2L2 mRNA
CTD
PMID:35283115
NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
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Best2
bestrophin 2
increases expression
EXP
Lidocaine results in increased expression of BEST2 mRNA
CTD
PMID:35283115
NCBI chr19:23,142,324...23,148,351
Ensembl chr19:23,141,602...23,148,339
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Birc5
baculoviral IAP repeat-containing 5
increases expression
EXP
Lidocaine results in increased expression of BIRC5 mRNA
CTD
PMID:35283115
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Blk
BLK proto-oncogene, Src family tyrosine kinase
increases expression
EXP
Lidocaine results in increased expression of BLK mRNA
CTD
PMID:35283115
NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
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Blnk
B-cell linker
increases expression
EXP
Lidocaine results in increased expression of BLNK mRNA
CTD
PMID:35283115
NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113
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Blvrb
biliverdin reductase B
decreases expression
EXP
Lidocaine results in decreased expression of BLVRB protein
CTD
PMID:27018092
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Bmf
Bcl2 modifying factor
increases expression
EXP
Lidocaine results in increased expression of BMF mRNA
CTD
PMID:35283115
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Bpifa5
BPI fold containing family A, member 5
decreases expression
EXP
Lidocaine results in decreased expression of BPIFA5 mRNA
CTD
PMID:35283115
NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883
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Bpifb2
BPI fold containing family B, member 2
decreases expression
EXP
Lidocaine results in decreased expression of BPIFB2 mRNA
CTD
PMID:35283115
NCBI chr 3:142,356,990...142,377,053
Ensembl chr 3:142,358,051...142,377,044
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Bsn
bassoon (presynaptic cytomatrix protein)
decreases expression
EXP
Lidocaine results in decreased expression of BSN mRNA
CTD
PMID:35283115
NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819
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Btc
betacellulin
increases expression
EXP
Lidocaine results in increased expression of BTC mRNA
CTD
PMID:35283115
NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
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Btnl5
butyrophilin-like 5
increases expression
EXP
Lidocaine results in increased expression of BTNL5 mRNA
CTD
PMID:35283115
NCBI chr20:4,366,780...4,376,385
Ensembl chr20:4,365,793...4,376,385
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Bub1
BUB1 mitotic checkpoint serine/threonine kinase
increases expression
EXP
Lidocaine results in increased expression of BUB1 mRNA
CTD
PMID:35283115
NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
increases expression
EXP
Lidocaine results in increased expression of BUB1B mRNA
CTD
PMID:35283115
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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C1qc
complement C1q C chain
increases expression
EXP
Lidocaine results in increased expression of C1QC mRNA
CTD
PMID:35283115
NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
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C9h6orf132
similar to human chromosome 6 open reading frame 132
increases expression
EXP
Lidocaine results in increased expression of C9H6ORF132 mRNA
CTD
PMID:35283115
NCBI chr 9:13,524,822...13,561,756
Ensembl chr 9:13,525,395...13,561,585
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Calca
calcitonin-related polypeptide alpha
increases secretion increases expression multiple interactions
ISO EXP
Lidocaine results in increased secretion of CALCA protein Lidocaine results in increased expression of CALCA mRNA capsazepine inhibits the reaction [Lidocaine results in increased secretion of CALCA protein]; TRPV1 protein affects the reaction [Lidocaine results in increased secretion of CALCA protein] Lidocaine inhibits the reaction [Potassium results in increased secretion of CALCA protein]
CTD
PMID:18172555 PMID:18178321 PMID:35283115
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Calhm2
calcium homeostasis modulator family member 2
increases expression
EXP
Lidocaine results in increased expression of CALHM2 mRNA
CTD
PMID:35283115
NCBI chr 1:246,022,324...246,028,050
Ensembl chr 1:246,022,324...246,028,218
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Capg
capping actin protein, gelsolin like
increases expression
EXP
Lidocaine results in increased expression of CAPG mRNA
CTD
PMID:35283115
NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
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Casp3
caspase 3
decreases expression decreases activity increases activity
ISO EXP
Lidocaine results in decreased expression of CASP3 protein Lidocaine results in decreased activity of CASP3 protein Lidocaine results in increased activity of CASP3 protein
CTD
PMID:15099683 PMID:17585225 PMID:20194319 PMID:21047305
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
decreases expression multiple interactions increases expression
ISO EXP
Lidocaine results in decreased expression of CASP9 protein cordycepin inhibits the reaction [Lidocaine results in increased expression of CASP9 mRNA]; cordycepin inhibits the reaction [Lidocaine results in increased expression of CASP9 protein] Lidocaine results in increased expression of CASP9 mRNA; Lidocaine results in increased expression of CASP9 protein
CTD
PMID:20194319 PMID:29382532
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Ccdc172
coiled-coil domain containing 172
decreases expression
EXP
Lidocaine results in decreased expression of CCDC172 mRNA
CTD
PMID:35283115
NCBI chr 1:257,629,188...257,682,373
Ensembl chr 1:257,629,208...257,675,247
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Ccdc42
coiled-coil domain containing 42
decreases expression
EXP
Lidocaine results in decreased expression of CCDC42 mRNA
CTD
PMID:35283115
NCBI chr10:53,289,956...53,300,135
Ensembl chr10:53,289,956...53,300,135
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Ccdc69
coiled-coil domain containing 69
increases expression
EXP
Lidocaine results in increased expression of CCDC69 mRNA
CTD
PMID:35283115
NCBI chr10:39,173,282...39,200,358
Ensembl chr10:39,173,282...39,199,878
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Ccdc71l
coiled-coil domain containing 71-like
decreases expression
EXP
Lidocaine results in decreased expression of CCDC71L mRNA
CTD
PMID:35283115
NCBI chr 6:48,960,020...48,964,112
Ensembl chr 6:48,960,191...48,960,841 Ensembl chr 6:48,960,191...48,960,841
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Ccl19
C-C motif chemokine ligand 19
decreases expression
EXP
Lidocaine results in decreased expression of CCL19 mRNA
CTD
PMID:35283115
NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
Lidocaine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Lidocaine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]
CTD
PMID:14570645
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl20
C-C motif chemokine ligand 20
decreases expression
EXP
Lidocaine results in decreased expression of CCL20 mRNA
CTD
PMID:35283115
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl3
C-C motif chemokine ligand 3
increases expression
EXP
Lidocaine results in increased expression of CCL3 mRNA
CTD
PMID:35283115
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl4
C-C motif chemokine ligand 4
increases expression
EXP
Lidocaine results in increased expression of CCL4 mRNA
CTD
PMID:35283115
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Ccl9
C-C motif chemokine ligand 9
increases expression
EXP
Lidocaine results in increased expression of CCL6 mRNA
CTD
PMID:35283115
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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Ccna1
cyclin A1
affects expression
ISO
Lidocaine affects the expression of CCNA1 mRNA
CTD
PMID:18931217
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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Ccna2
cyclin A2
affects expression increases expression
ISO EXP
Lidocaine affects the expression of CCNA2 mRNA Lidocaine results in increased expression of CCNA2 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
affects expression increases expression
ISO EXP
Lidocaine affects the expression of CCNB1 mRNA Lidocaine results in increased expression of CCNB1 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnb2
cyclin B2
affects expression increases expression
ISO EXP
Lidocaine affects the expression of CCNB2 mRNA Lidocaine results in increased expression of CCNB2 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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Ccnc
cyclin C
affects expression
ISO
Lidocaine affects the expression of CCNC mRNA
CTD
PMID:18931217
NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
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Ccnd1
cyclin D1
affects expression
ISO
Lidocaine affects the expression of CCND1 mRNA
CTD
PMID:18931217
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccne1
cyclin E1
affects expression
ISO
Lidocaine affects the expression of CCNE1 mRNA
CTD
PMID:18931217
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Ccnf
cyclin F
affects expression
ISO
Lidocaine affects the expression of CCNF mRNA
CTD
PMID:18931217
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
G
Ccr1
C-C motif chemokine receptor 1
decreases expression
EXP
Lidocaine results in decreased expression of CCR1 mRNA
CTD
PMID:35283115
NCBI chr 8:123,556,286...123,561,841
G
Cd200r1
CD200 receptor 1
increases expression
EXP
Lidocaine results in increased expression of CD200R1 mRNA
CTD
PMID:35283115
NCBI chr11:55,886,937...55,921,217
Ensembl chr11:55,887,717...55,921,285
G
Cd276
Cd276 molecule
increases expression
EXP
Lidocaine results in increased expression of CD276 mRNA
CTD
PMID:35283115
NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380
G
Cd34
CD34 molecule
increases expression
EXP
Lidocaine results in increased expression of CD34 mRNA
CTD
PMID:35283115
NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
G
Cd48
Cd48 molecule
increases expression
EXP
Lidocaine results in increased expression of CD48 mRNA
CTD
PMID:35283115
NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
G
Cd68
Cd68 molecule
increases expression
EXP
Lidocaine results in increased expression of CD68 mRNA
CTD
PMID:35283115
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
G
Cd72
Cd72 molecule
increases expression
EXP
Lidocaine results in increased expression of CD72 mRNA
CTD
PMID:35283115
NCBI chr 5:57,697,361...57,704,980
Ensembl chr 5:57,697,367...57,704,725
G
Cd84
CD84 molecule
increases expression
EXP
Lidocaine results in increased expression of CD84 mRNA
CTD
PMID:35283115
NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
G
Cd86
CD86 molecule
increases expression
EXP
Lidocaine results in increased expression of CD86 mRNA
CTD
PMID:35283115
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
G
Cdc20
cell division cycle 20
increases expression
EXP
Lidocaine results in increased expression of CDC20 mRNA
CTD
PMID:35283115
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
G
Cdc25c
cell division cycle 25C
increases expression
EXP
Lidocaine results in increased expression of CDC25C mRNA
CTD
PMID:35283115
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
G
Cdc45
cell division cycle 45
increases expression
EXP
Lidocaine results in increased expression of CDC45 mRNA
CTD
PMID:35283115
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
G
Cdc6
cell division cycle 6
increases expression
EXP
Lidocaine results in increased expression of CDC6 mRNA
CTD
PMID:35283115
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
G
Cdca3
cell division cycle associated 3
increases expression
EXP
Lidocaine results in increased expression of CDCA3 mRNA
CTD
PMID:35283115
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
G
Cdca7
cell division cycle associated 7
increases expression
EXP
Lidocaine results in increased expression of CDCA7 mRNA
CTD
PMID:35283115
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
G
Cdca7l
cell division cycle associated 7 like
increases expression
EXP
Lidocaine results in increased expression of CDCA7L mRNA
CTD
PMID:35283115
NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
G
Cdca8
cell division cycle associated 8
increases expression
EXP
Lidocaine results in increased expression of CDCA8 mRNA
CTD
PMID:35283115
NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
G
Cdhr3
cadherin-related family member 3
decreases expression
EXP
Lidocaine results in decreased expression of CDHR3 mRNA
CTD
PMID:35283115
NCBI chr 6:49,641,833...49,702,016
Ensembl chr 6:49,641,813...49,702,017
G
Cdk1
cyclin-dependent kinase 1
increases expression
EXP
Lidocaine results in increased expression of CDK1 mRNA
CTD
PMID:35283115
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdk2
cyclin dependent kinase 2
affects expression increases expression
ISO EXP
Lidocaine affects the expression of CDK2 mRNA Lidocaine results in increased expression of CDK2 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
G
Cdk4
cyclin-dependent kinase 4
affects expression
ISO
Lidocaine affects the expression of CDK4 mRNA
CTD
PMID:18931217
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
G
Cdk6
cyclin-dependent kinase 6
increases expression
EXP
Lidocaine results in increased expression of CDK6 mRNA
CTD
PMID:35283115
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
G
Cdkl4
cyclin-dependent kinase-like 4
decreases expression
EXP
Lidocaine results in decreased expression of CDKL4 mRNA
CTD
PMID:35283115
NCBI chr 6:14,449,822...14,492,568
Ensembl chr 6:14,450,681...14,492,046
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
affects expression increases expression
ISO EXP
Lidocaine affects the expression of CDKN1A mRNA Lidocaine results in increased expression of CDKN1A mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
affects expression
ISO
Lidocaine affects the expression of CDKN1B mRNA
CTD
PMID:18931217
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn2a
cyclin-dependent kinase inhibitor 2A
affects expression
ISO
Lidocaine affects the expression of CDKN2A mRNA
CTD
PMID:18931217
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
G
Cdkn2c
cyclin-dependent kinase inhibitor 2C
increases expression
EXP
Lidocaine results in increased expression of CDKN2C mRNA
CTD
PMID:35283115
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
G
Cdt1
chromatin licensing and DNA replication factor 1
increases expression
EXP
Lidocaine results in increased expression of CDT1 mRNA
CTD
PMID:35283115
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
G
Ceacam4
CEA cell adhesion molecule 4
increases expression
EXP
Lidocaine results in increased expression of CEACAM4 mRNA
CTD
PMID:35283115
NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915
G
Cenpa
centromere protein A
increases expression
EXP
Lidocaine results in increased expression of CENPA mRNA
CTD
PMID:35283115
NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
G
Cenpe
centromere protein E
increases expression
EXP
Lidocaine results in increased expression of CENPE mRNA
CTD
PMID:35283115
NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
G
Cenph
centromere protein H
increases expression
EXP
Lidocaine results in increased expression of CENPH mRNA
CTD
PMID:35283115
NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154
G
Cenpm
centromere protein M
increases expression
EXP
Lidocaine results in increased expression of CENPM mRNA
CTD
PMID:35283115
NCBI chr 7:113,748,026...113,759,296
Ensembl chr 7:113,747,516...113,764,258
G
Cenpo
centromere protein O
increases expression
EXP
Lidocaine results in increased expression of CENPO mRNA
CTD
PMID:35283115
NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314
G
Cenpt
centromere protein T
increases expression
EXP
Lidocaine results in increased expression of CENPT mRNA
CTD
PMID:35283115
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
G
Cenpu
centromere protein U
increases expression
EXP
Lidocaine results in increased expression of CENPU mRNA
CTD
PMID:35283115
NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
G
Cenpw
centromere protein W
increases expression
EXP
Lidocaine results in increased expression of CENPW mRNA
CTD
PMID:35283115
NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
G
Cep55
centrosomal protein 55
increases expression
EXP
Lidocaine results in increased expression of CEP55 mRNA
CTD
PMID:35283115
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
G
Cep72
centrosomal protein 72
increases expression
EXP
Lidocaine results in increased expression of CEP72 mRNA
CTD
PMID:35283115
NCBI chr 1:29,225,312...29,255,294
Ensembl chr 1:29,225,361...29,255,271
G
Ces1d
carboxylesterase 1D
increases hydrolysis
EXP
CES1D protein results in increased hydrolysis of Lidocaine
CTD
PMID:12019189
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
G
Cesl1
carboxylesterase-like 1
decreases expression
EXP
Lidocaine results in decreased expression of CESL1 mRNA
CTD
PMID:35283115
NCBI chr19:22,670,709...23,006,329
Ensembl chr19:22,670,712...22,712,608
G
Cfd
complement factor D
increases expression
EXP
Lidocaine results in increased expression of CFD mRNA
CTD
PMID:35283115
NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
G
Cgas
cyclic GMP-AMP synthase
increases expression
EXP
Lidocaine results in increased expression of CGAS mRNA
CTD
PMID:35283115
NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
G
Chaf1b
chromatin assembly factor 1 subunit B
increases expression
EXP
Lidocaine results in increased expression of CHAF1B mRNA
CTD
PMID:35283115
NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070
G
Chodl
chondrolectin
decreases expression
EXP
Lidocaine results in decreased expression of CHODL mRNA
CTD
PMID:35283115
NCBI chr11:17,654,137...17,676,450
Ensembl chr11:17,654,206...17,676,441
G
Chtf18
chromosome transmission fidelity factor 18
increases expression
EXP
Lidocaine results in increased expression of CHTF18 mRNA
CTD
PMID:35283115
NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
G
Cip2a
cellular inhibitor of PP2A
increases expression
EXP
Lidocaine results in increased expression of CIP2A mRNA
CTD
PMID:35283115
NCBI chr11:51,792,143...51,823,016
Ensembl chr11:51,795,024...51,822,938
G
Ckap2
cytoskeleton associated protein 2
increases expression
EXP
Lidocaine results in increased expression of CKAP2 mRNA
CTD
PMID:35283115
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
G
Cks1l
CDC28 protein kinase regulatory subunit 1-like
increases expression
EXP
Lidocaine results in increased expression of CKS1L mRNA
CTD
PMID:35283115
NCBI chr 5:106,982,443...106,983,182
Ensembl chr 5:106,982,882...106,983,121
G
Cks2
CDC28 protein kinase regulatory subunit 2
increases expression
EXP
Lidocaine results in increased expression of CKS2 mRNA
CTD
PMID:35283115
NCBI chr17:13,570,611...13,575,770
G
Clca4l
chloride channel calcium activated 4-like
increases expression
EXP
Lidocaine results in increased expression of CLCA4L mRNA
CTD
PMID:35283115
NCBI chr 2:233,826,133...233,846,137
Ensembl chr 2:233,826,133...233,846,716
G
Clcf1
cardiotrophin-like cytokine factor 1
increases expression
EXP
Lidocaine results in increased expression of CLCF1 mRNA
CTD
PMID:35283115
NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
G
Cldn14
claudin 14
increases expression
EXP
Lidocaine results in increased expression of CLDN14 mRNA
CTD
PMID:35283115
NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
G
Cldn23
claudin 23
increases expression
EXP
Lidocaine results in increased expression of CLDN23 mRNA
CTD
PMID:35283115
NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
G
Clec12a
C-type lectin domain family 12, member A
increases expression
EXP
Lidocaine results in increased expression of CLEC12A mRNA
CTD
PMID:35283115
NCBI chr 4:162,798,125...162,816,757
Ensembl chr 4:162,798,125...162,816,753
G
Clec2d
C-type lectin domain family 2, member D
increases expression
EXP
Lidocaine results in increased expression of CLEC2D mRNA
CTD
PMID:35283115
NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527
G
Clec4e
C-type lectin domain family 4, member E
decreases expression
EXP
Lidocaine results in decreased expression of CLEC4E mRNA
CTD
PMID:35283115
NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
G
Clec7a
C-type lectin domain containing 7A
increases expression
EXP
Lidocaine results in increased expression of CLEC7A mRNA
CTD
PMID:35283115
NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
G
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
increases expression
EXP
Lidocaine results in increased expression of CMTM3 mRNA
CTD
PMID:35283115
NCBI chr19:622,563...630,721
Ensembl chr19:604,458...629,790
G
Cndp1
carnosine dipeptidase 1
increases expression
EXP
Lidocaine results in increased expression of CNDP1 mRNA
CTD
PMID:35283115
NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765
G
Cnga2
cyclic nucleotide gated channel subunit alpha 2
increases expression
EXP
Lidocaine results in increased expression of CNGA2 mRNA
CTD
PMID:35283115
NCBI chr X:149,696,999...149,715,051
Ensembl chr X:149,696,997...149,715,051
G
Cnr2
cannabinoid receptor 2
increases expression
EXP
Lidocaine results in increased expression of CNR2 mRNA
CTD
PMID:35283115
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
G
Cntn5
contactin 5
decreases expression
EXP
Lidocaine results in decreased expression of CNTN5 mRNA
CTD
PMID:35283115
NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957
G
Cntnap1
contactin associated protein 1
decreases expression
EXP
Lidocaine results in decreased expression of CNTNAP1 mRNA
CTD
PMID:35283115
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
G
Cntnap3
contactin associated protein family member 3
increases expression
EXP
Lidocaine results in increased expression of CNTNAP3 mRNA
CTD
PMID:35283115
NCBI chr17:267,379...455,478
Ensembl chr17:267,508...454,102
G
Cp
ceruloplasmin
decreases expression
EXP
Lidocaine results in decreased expression of CP mRNA
CTD
PMID:35283115
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Crh
corticotropin releasing hormone
increases expression
EXP
Lidocaine results in increased expression of CRH mRNA
CTD
PMID:35283115
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Crispld1
cysteine-rich secretory protein LCCL domain containing 1
decreases expression
EXP
Lidocaine results in decreased expression of CRISPLD1 mRNA
CTD
PMID:35283115
NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
G
Crtap
cartilage associated protein
increases expression
EXP
Lidocaine results in increased expression of CRTAP mRNA
CTD
PMID:35283115
NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631
G
Csf2ra
colony stimulating factor 2 receptor subunit alpha
increases expression
EXP
Lidocaine results in increased expression of CSF2RA mRNA
CTD
PMID:35283115
NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128
G
Csrp3
cysteine and glycine rich protein 3
increases expression
EXP
Lidocaine results in increased expression of CSRP3 mRNA
CTD
PMID:35283115
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
G
Ctsc
cathepsin C
increases expression
EXP
Lidocaine results in increased expression of CTSC mRNA
CTD
PMID:35283115
NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
G
Ctsz
cathepsin Z
increases expression
EXP
Lidocaine results in increased expression of CTSZ mRNA
CTD
PMID:35283115
NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645
G
Cux1
cut-like homeobox 1
increases expression
EXP
Lidocaine results in increased expression of CUX1 mRNA
CTD
PMID:35283115
NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866 Ensembl chr 4:20,107,311...20,425,866
G
Cxcl1
C-X-C motif chemokine ligand 1
decreases expression
EXP
Lidocaine results in decreased expression of CXCL1 mRNA
CTD
PMID:35283115
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
G
Cxcl12
C-X-C motif chemokine ligand 12
decreases expression
EXP
Lidocaine results in decreased expression of CXCL12 mRNA
CTD
PMID:35283115
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
G
Cxcl13
C-X-C motif chemokine ligand 13
decreases expression
EXP
Lidocaine results in decreased expression of CXCL13 mRNA
CTD
PMID:35283115
NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
G
Cxcl16
C-X-C motif chemokine ligand 16
increases expression
EXP
Lidocaine results in increased expression of CXCL16 mRNA
CTD
PMID:35283115
NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
G
Cybb
cytochrome b-245 beta chain
increases expression
EXP
Lidocaine results in increased expression of CYBB mRNA
CTD
PMID:35283115
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
affects metabolic processing
ISO
CYP1A2 protein affects the metabolism of Lidocaine
CTD
PMID:15447735
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp2ac1
cytochrome P450, family 2, subfamily ac, polypeptide 1
decreases expression
EXP
Lidocaine results in decreased expression of CYP2AC1 mRNA
CTD
PMID:35283115
NCBI chr 9:20,035,823...20,058,570
Ensembl chr 9:20,033,780...20,058,837
G
Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
increases expression
EXP
Lidocaine results in increased expression of CYP2D1 mRNA
CTD
PMID:35283115
NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084
G
Cyp2d5
cytochrome P450, family 2, subfamily d, polypeptide 5
increases expression
EXP
Lidocaine results in increased expression of CYP2D5 mRNA
CTD
PMID:35283115
NCBI chr 7:113,899,905...113,904,458
Ensembl chr 7:113,899,890...113,904,495
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions increases metabolic processing decreases methylation affects metabolic processing decreases ethylation
ISO
Rifampin promotes the reaction [CYP3A4 protein results in increased metabolism of Lidocaine] CYP3A4 protein results in decreased methylation of Lidocaine CYP3A4 protein affects the metabolism of Lidocaine CYP3A4 protein results in decreased ethylation of Lidocaine
CTD
PMID:9298257 PMID:15383492 PMID:15447735 PMID:15887009 PMID:18846481
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
decreases methylation
ISO
CYP3A5 protein results in decreased methylation of Lidocaine
CTD
PMID:15383492
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
G
Cytip
cytohesin 1 interacting protein
increases expression
EXP
Lidocaine results in increased expression of CYTIP mRNA
CTD
PMID:35283115
NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
G
Dapl1
death associated protein-like 1
increases expression
EXP
Lidocaine results in increased expression of DAPL1 mRNA
CTD
PMID:35283115
NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
G
Dbf4
DBF4-CDC7 kinase regulatory subunit
increases expression
EXP
Lidocaine results in increased expression of DBF4 mRNA
CTD
PMID:35283115
NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
G
Dcn
decorin
decreases expression
EXP
Lidocaine results in decreased expression of DCN mRNA
CTD
PMID:35283115
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
G
Ddah2
DDAH family member 2, ADMA-independent
decreases expression increases expression
EXP
Lidocaine results in decreased expression of DDAH2 protein Lidocaine results in increased expression of DDAH2 mRNA
CTD
PMID:27018092
NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
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Ddias
DNA damage-induced apoptosis suppressor
increases expression
EXP
Lidocaine results in increased expression of DDIAS mRNA
CTD
PMID:35283115
NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
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Ddx60
DEXD/H-box helicase 60
increases expression
EXP
Lidocaine results in increased expression of DDX60 mRNA
CTD
PMID:35283115
NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526
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Dennd2d
DENN domain containing 2D
increases expression
EXP
Lidocaine results in increased expression of DENND2D mRNA
CTD
PMID:35283115
NCBI chr 2:193,973,231...193,992,275
Ensembl chr 2:193,973,231...193,992,270
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Deptor
DEP domain containing MTOR-interacting protein
multiple interactions
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; dorsomorphin inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]; MK-8722 promotes the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]
CTD
PMID:37914286
NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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Diaph3
diaphanous-related formin 3
increases expression
EXP
Lidocaine results in increased expression of DIAPH3 mRNA
CTD
PMID:35283115
NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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Dio3
iodothyronine deiodinase 3
decreases expression
EXP
Lidocaine results in decreased expression of DIO3 mRNA
CTD
PMID:35283115
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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Dlgap5
DLG associated protein 5
increases expression
EXP
Lidocaine results in increased expression of DLGAP5 mRNA
CTD
PMID:35283115
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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Dnajb7
DnaJ heat shock protein family (Hsp40) member B7
decreases expression
EXP
Lidocaine results in decreased expression of DNAJB7 mRNA
CTD
PMID:35283115
NCBI chr 7:112,932,736...112,934,050
Ensembl chr 7:112,932,616...112,945,537
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Dnajc22
DnaJ heat shock protein family (Hsp40) member C22
increases expression
EXP
Lidocaine results in increased expression of DNAJC22 mRNA
CTD
PMID:35283115
NCBI chr 7:130,257,504...130,262,880
Ensembl chr 7:130,257,851...130,263,230
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Dnase2
deoxyribonuclease 2, lysosomal
increases expression
EXP
Lidocaine results in increased expression of DNASE2 mRNA
CTD
PMID:35283115
NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376
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Dock8
dedicator of cytokinesis 8
increases expression
EXP
Lidocaine results in increased expression of DOCK8 mRNA
CTD
PMID:35283115
NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474
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Dpep2
dipeptidase 2
increases expression
EXP
Lidocaine results in increased expression of DPEP2 mRNA
CTD
PMID:35283115
NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
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Dph6
diphthamine biosynthesis 6
decreases expression
EXP
Lidocaine results in decreased expression of DPH6 mRNA
CTD
PMID:35283115
NCBI chr 3:101,307,229...101,437,463
Ensembl chr 3:101,307,231...101,534,603
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Dscc1
DNA replication and sister chromatid cohesion 1
increases expression
EXP
Lidocaine results in increased expression of DSCC1 mRNA
CTD
PMID:35283115
NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
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Dtl
denticleless E3 ubiquitin protein ligase homolog
decreases expression
EXP
Lidocaine results in decreased expression of DTL mRNA
CTD
PMID:35283115
NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
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Dtx4
deltex E3 ubiquitin ligase 4
increases expression
EXP
Lidocaine results in increased expression of DTX4 mRNA
CTD
PMID:35283115
NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
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E2f1
E2F transcription factor 1
affects expression
ISO
Lidocaine affects the expression of E2F1 mRNA
CTD
PMID:18931217
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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E2f2
E2F transcription factor 2
affects expression
ISO
Lidocaine affects the expression of E2F2 mRNA
CTD
PMID:18931217
NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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E2f3
E2F transcription factor 3
affects expression increases expression
ISO EXP
Lidocaine affects the expression of E2F3 mRNA Lidocaine results in increased expression of E2F3 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
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E2f4
E2F transcription factor 4
affects expression
ISO
Lidocaine affects the expression of E2F4 mRNA
CTD
PMID:18931217
NCBI chr19:33,174,396...33,181,806
Ensembl chr19:33,174,410...33,181,806
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Ect2
epithelial cell transforming 2
increases expression
EXP
Lidocaine results in increased expression of ECT2 mRNA
CTD
PMID:35283115
NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
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Efcab11
EF-hand calcium binding domain 11
increases expression
EXP
Lidocaine results in increased expression of EFCAB11 mRNA
CTD
PMID:35283115
NCBI chr 6:119,008,908...119,162,994
Ensembl chr 6:119,008,919...119,162,046
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Egr1
early growth response 1
increases expression
EXP
Lidocaine results in increased expression of EGR1 mRNA
CTD
PMID:35283115
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Egr2
early growth response 2
increases expression
EXP
Lidocaine results in increased expression of EGR2 mRNA
CTD
PMID:35283115
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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Eme1
essential meiotic structure-specific endonuclease 1
increases expression
EXP
Lidocaine results in increased expression of EME1 mRNA
CTD
PMID:35283115
NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435
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Emp1
epithelial membrane protein 1
increases expression
EXP
Lidocaine results in increased expression of EMP1 mRNA
CTD
PMID:35283115
NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
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Emp3
epithelial membrane protein 3
increases expression
EXP
Lidocaine results in increased expression of EMP3 mRNA
CTD
PMID:35283115
NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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Engase
endo-beta-N-acetylglucosaminidase
increases expression
EXP
Lidocaine results in increased expression of ENGASE mRNA
CTD
PMID:35283115
NCBI chr10:103,707,169...103,719,833
Ensembl chr10:103,707,169...103,719,819
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Epcam
epithelial cell adhesion molecule
increases expression
EXP
Lidocaine results in increased expression of EPCAM mRNA
CTD
PMID:35283115
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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Epor
erythropoietin receptor
increases expression
EXP
Lidocaine results in increased expression of EPOR mRNA
CTD
PMID:35283115
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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Epsti1
epithelial stromal interaction 1
increases expression
EXP
Lidocaine results in increased expression of EPSTI1 mRNA
CTD
PMID:35283115
NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191
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Ercc6l
ERCC excision repair 6 like, spindle assembly checkpoint helicase
increases expression
EXP
Lidocaine results in increased expression of ERCC6L mRNA
CTD
PMID:35283115
NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
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Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
increases expression
EXP
Lidocaine results in increased expression of ESCO2 mRNA
CTD
PMID:35283115
NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
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Esco2-ps1
establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 1
increases expression
EXP
Lidocaine results in increased expression of ESCO2-PS1 mRNA
CTD
PMID:35283115
NCBI chr 7:63,948,207...63,951,641
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Esm1
endothelial cell-specific molecule 1
decreases expression
EXP
Lidocaine results in decreased expression of ESM1 mRNA
CTD
PMID:35283115
NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
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Espl1
extra spindle pole bodies like 1, separase
increases expression
EXP
Lidocaine results in increased expression of ESPL1 mRNA
CTD
PMID:35283115
NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
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Esr1
estrogen receptor 1
increases expression
ISO
Lidocaine results in increased expression of ESR1 mRNA
CTD
PMID:22083529
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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F10
coagulation factor X
increases expression
EXP
Lidocaine results in increased expression of F10 mRNA
CTD
PMID:35283115
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
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F2rl3
F2R like thrombin or trypsin receptor 3
increases expression
EXP
Lidocaine results in increased expression of F2RL3 mRNA
CTD
PMID:35283115
NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
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Fam72a
family with sequence similarity 72, member A
increases expression
EXP
Lidocaine results in increased expression of FAM72A mRNA
CTD
PMID:35283115
NCBI chr13:42,967,701...42,979,083
Ensembl chr13:42,967,578...42,984,208
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Fancd2
FA complementation group D2
increases expression
EXP
Lidocaine results in increased expression of FANCD2 mRNA
CTD
PMID:35283115
NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
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Fbln2
fibulin 2
increases expression
EXP
Lidocaine results in increased expression of FBLN2 mRNA
CTD
PMID:35283115
NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
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Fbxl21
F-box and leucine-rich repeat protein 21
increases expression
EXP
Lidocaine results in increased expression of FBXL21 mRNA
CTD
PMID:35283115
NCBI chr17:8,060,412...8,077,415
Ensembl chr17:8,060,414...8,073,359
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Fbxo5
F-box protein 5
increases expression
EXP
Lidocaine results in increased expression of FBXO5 mRNA
CTD
PMID:35283115
NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
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Fcrl2
Fc receptor-like 2
increases expression
EXP
Lidocaine results in increased expression of FCRL2 mRNA
CTD
PMID:35283115
NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
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Fgd2
FYVE, RhoGEF and PH domain containing 2
increases expression
EXP
Lidocaine results in increased expression of FGD2 mRNA
CTD
PMID:35283115
NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603
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Fgf20
fibroblast growth factor 20
decreases expression
EXP
Lidocaine results in decreased expression of FGF20 mRNA
CTD
PMID:35283115
NCBI chr16:52,030,549...52,038,201
Ensembl chr16:52,010,194...52,038,204
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Fgfbp1
fibroblast growth factor binding protein 1
decreases expression
EXP
Lidocaine results in decreased expression of FGFBP1 mRNA
CTD
PMID:35283115
NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
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Fignl1
fidgetin-like 1
increases expression
EXP
Lidocaine results in increased expression of FIGNL1 mRNA
CTD
PMID:35283115
NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
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Fitm1
fat storage-inducing transmembrane protein 1
increases expression
EXP
Lidocaine results in increased expression of FITM1 mRNA
CTD
PMID:35283115
NCBI chr15:29,064,746...29,066,015
Ensembl chr15:29,064,707...29,066,015
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Flnc
filamin C
increases expression
EXP
Lidocaine results in increased expression of FLNC mRNA
CTD
PMID:35283115
NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
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Flt3
Fms related receptor tyrosine kinase 3
decreases expression
EXP
Lidocaine results in decreased expression of FLT3 mRNA
CTD
PMID:35283115
NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474
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Fmo13
flavin-containing monooxygenase 13
decreases expression
EXP
Lidocaine results in decreased expression of FMO13 mRNA
CTD
PMID:35283115
NCBI chr13:78,726,398...78,738,178
Ensembl chr13:78,726,398...78,738,178
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Folr2
folate receptor beta
increases expression
EXP
Lidocaine results in increased expression of FOLR2 mRNA
CTD
PMID:35283115
NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions affects expression
ISO EXP
Lidocaine inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]] Lidocaine inhibits the reaction [Propofol results in increased expression of FOS protein] Lidocaine affects the expression of FOS protein
CTD
PMID:7887109 PMID:17136530 PMID:20950675
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fscn3
fascin actin-bundling protein 3
increases expression
EXP
Lidocaine results in increased expression of FSCN3 mRNA
CTD
PMID:35283115
NCBI chr 4:57,042,797...57,052,224
Ensembl chr 4:57,042,797...57,052,404
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Ftl1l5
ferritin light chain 1 like 5
increases expression
EXP
Lidocaine results in increased expression of FTL1L5 mRNA
CTD
PMID:35283115
NCBI chr 7:12,220,109...12,221,018
Ensembl chr 7:12,220,103...12,221,023 Ensembl chr 2:12,220,103...12,221,023
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Galc
galactosylceramidase
increases expression
EXP
Lidocaine results in increased expression of GALC mRNA
CTD
PMID:35283115
NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830
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Galnt3
polypeptide N-acetylgalactosaminyltransferase 3
increases expression
EXP
Lidocaine results in increased expression of GALNT3 mRNA
CTD
PMID:35283115
NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
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Gask1b
golgi associated kinase 1B
increases expression
EXP
Lidocaine results in increased expression of FAM198B mRNA
CTD
PMID:35283115
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
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Gdf15
growth differentiation factor 15
increases expression
EXP
Lidocaine results in increased expression of GDF15 mRNA
CTD
PMID:35283115
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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Gdf3
growth differentiation factor 3
increases expression
EXP
Lidocaine results in increased expression of GDF3 mRNA
CTD
PMID:35283115
NCBI chr 4:155,831,572...155,835,953
Ensembl chr 4:155,830,909...155,835,937
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Gdf7
growth differentiation factor 7
decreases expression
EXP
Lidocaine results in decreased expression of GDF7 mRNA
CTD
PMID:35283115
NCBI chr 6:31,171,495...31,182,484
Ensembl chr 6:31,178,119...31,182,447
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Gdnf
glial cell derived neurotrophic factor
increases expression
EXP
Lidocaine results in increased expression of GDNF mRNA
CTD
PMID:35283115
NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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Gen1
GEN1 Holliday junction 5' flap endonuclease
increases expression
EXP
Lidocaine results in increased expression of GEN1 mRNA
CTD
PMID:35283115
NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401
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Gins1
GINS complex subunit 1
increases expression
EXP
Lidocaine results in increased expression of GINS1 mRNA
CTD
PMID:35283115
NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
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Gldn
gliomedin
increases expression
EXP
Lidocaine results in increased expression of GLDN mRNA
CTD
PMID:35283115
NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196
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Glipr1
GLI pathogenesis-related 1
increases expression
EXP
Lidocaine results in increased expression of GLIPR1 mRNA
CTD
PMID:35283115
NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
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Gnb2
G protein subunit beta 2
increases expression
EXP
Lidocaine results in increased expression of GNB2 mRNA; Lidocaine results in increased expression of GNB2 protein
CTD
PMID:27018092
NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
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Gpnmb
glycoprotein nmb
increases expression
EXP
Lidocaine results in increased expression of GPNMB mRNA
CTD
PMID:35283115
NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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Gpr182
G protein-coupled receptor 182
decreases expression
EXP
Lidocaine results in decreased expression of GPR182 mRNA
CTD
PMID:35283115
NCBI chr 7:63,585,997...63,589,088
Ensembl chr 7:63,578,750...63,589,210
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Gpr31
G protein-coupled receptor 31
increases expression
EXP
Lidocaine results in increased expression of GPR31 mRNA
CTD
PMID:35283115
NCBI chr 1:52,926,953...52,927,912
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Gpr34
G protein-coupled receptor 34
increases expression
EXP
Lidocaine results in increased expression of GPR34 mRNA
CTD
PMID:35283115
NCBI chr X:9,104,829...9,113,796
Ensembl chr X:9,104,565...9,148,601
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Gpr65
G-protein coupled receptor 65
increases expression
EXP
Lidocaine results in increased expression of GPR65 mRNA
CTD
PMID:35283115
NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
G
Grn
granulin precursor
increases expression
EXP
Lidocaine results in increased expression of GRN mRNA
CTD
PMID:35283115
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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Gsg1
germ cell associated 1
increases expression
EXP
Lidocaine results in increased expression of GSG1 mRNA
CTD
PMID:35283115
NCBI chr 4:168,090,773...168,107,039
Ensembl chr 4:168,090,776...168,107,039
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H19
H19 imprinted maternally expressed transcript
increases expression
EXP
Lidocaine results in increased expression of H19 mRNA
CTD
PMID:35283115
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
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H2ac25
H2A clustered histone 25
decreases expression
EXP
Lidocaine results in decreased expression of H2AC25 mRNA
CTD
PMID:35283115
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
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Haspin
histone H3 associated protein kinase
increases expression
EXP
Lidocaine results in increased expression of GSG2 mRNA
CTD
PMID:35283115
NCBI chr10:57,747,731...57,750,518
Ensembl chr10:57,747,573...57,750,512
G
Havcr1
hepatitis A virus cellular receptor 1
increases expression
EXP
Lidocaine results in increased expression of HAVCR1 mRNA
CTD
PMID:35283115
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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Havcr2
hepatitis A virus cellular receptor 2
increases expression
EXP
Lidocaine results in increased expression of HAVCR2 mRNA
CTD
PMID:35283115
NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
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Hbegf
heparin-binding EGF-like growth factor
increases expression
EXP
Lidocaine results in increased expression of HBEGF mRNA
CTD
PMID:35283115
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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Hcls1
hematopoietic cell specific Lyn substrate 1
increases expression
EXP
Lidocaine results in increased expression of HCLS1 mRNA
CTD
PMID:35283115
NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014
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Hcst
hematopoietic cell signal transducer
increases expression
EXP
Lidocaine results in increased expression of HCST mRNA
CTD
PMID:35283115
NCBI chr 1:85,676,976...85,679,083
Ensembl chr 1:85,676,979...85,679,012
G
Hebp2
heme binding protein 2
decreases expression
EXP
Lidocaine results in decreased expression of HEBP2 mRNA
CTD
PMID:35283115
NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
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Hgd
homogentisate 1, 2-dioxygenase
increases expression
EXP
Lidocaine results in increased expression of HGD mRNA
CTD
PMID:35283115
NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
G
Hils1
histone linker H1 domain, spermatid-specific 1
increases expression
EXP
Lidocaine results in increased expression of HILS1 mRNA
CTD
PMID:35283115
NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321
G
Hist1h2af
histone cluster 1 H2A family member F
increases expression
EXP
Lidocaine results in increased expression of HIST1H2AF mRNA
CTD
PMID:35283115
NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
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Hist1h2ah
histone cluster 1 H2A family member H
increases expression
EXP
Lidocaine results in increased expression of HIST1H2AH mRNA
CTD
PMID:35283115
NCBI chr17:41,384,521...41,385,018
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Hk3
hexokinase 3
increases expression
EXP
Lidocaine results in increased expression of HK3 mRNA
CTD
PMID:35283115
NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863
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Hmgb1
high mobility group box 1
multiple interactions
ISO
Lidocaine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased localization of HMGB1 protein]; Lidocaine inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 mRNA]
CTD
PMID:21288974
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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Hmgb2
high mobility group box 2
increases expression
EXP
Lidocaine results in increased expression of HMGB2 mRNA
CTD
PMID:35283115
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 Ensembl chr 1:32,710,658...32,713,140
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Hmgb2-ps6
high mobility group box 2, pseudogene 6
increases expression
EXP
Lidocaine results in increased expression of HMGB2-PS6 mRNA
CTD
PMID:35283115
NCBI chr 1:19,409,161...19,410,260
Ensembl chr 1:19,409,539...19,410,168
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Hmgb2l1
high mobility group box 2-like 1
increases expression
EXP
Lidocaine results in increased expression of HMGB2L1 mRNA
CTD
PMID:35283115
NCBI chr11:47,252,583...47,253,646
Ensembl chr11:47,252,569...47,253,669 Ensembl chr 1:47,252,569...47,253,669
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Hmgb2l2
high mobility group box 2 like 2
increases expression
EXP
Lidocaine results in increased expression of HMGB2L2 mRNA
CTD
PMID:35283115
NCBI chr14:69,045,590...69,046,623
Ensembl chr14:69,045,641...69,046,640 Ensembl chr 1:69,045,641...69,046,640
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Hmmr
hyaluronan-mediated motility receptor
increases expression
EXP
Lidocaine results in increased expression of HMMR mRNA
CTD
PMID:35283115
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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Hmox1
heme oxygenase 1
increases expression
EXP
Lidocaine results in increased expression of HMOX1 mRNA
CTD
PMID:35283115
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hormad2
HORMA domain containing 2
increases expression
EXP
Lidocaine results in increased expression of HORMAD2 mRNA
CTD
PMID:35283115
NCBI chr14:79,215,013...79,300,447
Ensembl chr14:79,214,998...79,299,910
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Hpgd
15-hydroxyprostaglandin dehydrogenase
increases expression
EXP
Lidocaine results in increased expression of HPGD mRNA
CTD
PMID:35283115
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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Hpgds
hematopoietic prostaglandin D synthase
increases expression
EXP
Lidocaine results in increased expression of HPGDS mRNA
CTD
PMID:35283115
NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883
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Hrh1
histamine receptor H 1
affects binding multiple interactions
ISO
HRH1 protein binds to Lidocaine [HRH1 protein binds to Lidocaine] which results in increased import of Calcium
CTD
PMID:32061592
NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
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Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
EXP
Lidocaine results in increased expression of HSPA1B mRNA
CTD
PMID:35283115
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
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Hvcn1
hydrogen voltage-gated channel 1
increases expression
EXP
Lidocaine results in increased expression of HVCN1 mRNA
CTD
PMID:35283115
NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
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Ifi30
IFI30, lysosomal thiol reductase
increases expression
EXP
Lidocaine results in increased expression of IFI30 mRNA
CTD
PMID:35283115
NCBI chr16:18,675,590...18,679,655
Ensembl chr16:18,675,613...18,681,175
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Ifi44l
interferon-induced protein 44-like
increases expression
EXP
Lidocaine results in increased expression of IFI44L mRNA
CTD
PMID:35283115
NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
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Ifit1bl
interferon-induced protein with tetratricopeptide repeats 1B-like
decreases expression
EXP
Lidocaine results in decreased expression of IFIT1BL mRNA
CTD
PMID:35283115
NCBI chr 1:232,122,618...232,167,317
Ensembl chr 1:232,122,562...232,167,518
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Igf1
insulin-like growth factor 1
increases expression
EXP
Lidocaine results in increased expression of IGF1 mRNA
CTD
PMID:35283115
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igfbp2
insulin-like growth factor binding protein 2
increases expression
EXP
Lidocaine results in increased expression of IGFBP2 mRNA
CTD
PMID:35283115
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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Il10ra
interleukin 10 receptor subunit alpha
increases expression
EXP
Lidocaine results in increased expression of IL10RA mRNA
CTD
PMID:35283115
NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
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Il13
interleukin 13
decreases expression
ISO
Lidocaine results in decreased expression of IL13 protein
CTD
PMID:18382663
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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Il16
interleukin 16
increases expression
EXP
Lidocaine results in increased expression of IL16 mRNA
CTD
PMID:35283115
NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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Il1rap
interleukin 1 receptor accessory protein
increases expression
EXP
Lidocaine results in increased expression of IL1RAP mRNA
CTD
PMID:35283115
NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
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Il33
interleukin 33
increases expression
EXP
Lidocaine results in increased expression of IL33 mRNA
CTD
PMID:35283115
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Il4
interleukin 4
decreases expression
ISO
Lidocaine results in decreased expression of IL4 protein
CTD
PMID:18382663
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
decreases expression
ISO
Lidocaine results in decreased expression of IL6 protein
CTD
PMID:16378115
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Inava
innate immunity activator
increases expression
EXP
Lidocaine results in increased expression of INAVA mRNA
CTD
PMID:35283115
NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729
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Insyn2b
inhibitory synaptic factor family member 2B
decreases expression
EXP
Lidocaine results in decreased expression of INSYN2B mRNA
CTD
PMID:35283115
NCBI chr10:18,916,721...19,023,859
Ensembl chr10:19,003,131...19,022,139
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Iqgap3
IQ motif containing GTPase activating protein 3
increases expression
EXP
Lidocaine results in increased expression of IQGAP3 mRNA
CTD
PMID:35283115
NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956
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Irak2
interleukin-1 receptor-associated kinase 2
increases expression
EXP
Lidocaine results in increased expression of IRAK2 mRNA
CTD
PMID:35283115
NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
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Irf5
interferon regulatory factor 5
increases expression
EXP
Lidocaine results in increased expression of IRF5 mRNA
CTD
PMID:35283115
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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Irf8
interferon regulatory factor 8
increases expression
EXP
Lidocaine results in increased expression of IRF8 mRNA
CTD
PMID:35283115
NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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Isg20
interferon stimulated exonuclease gene 20
increases expression
EXP
Lidocaine results in increased expression of ISG20 mRNA
CTD
PMID:35283115
NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
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Itga4
integrin subunit alpha 4
increases expression
EXP
Lidocaine results in increased expression of ITGA4 mRNA
CTD
PMID:35283115
NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
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Itga5
integrin subunit alpha 5
increases expression
EXP
Lidocaine results in increased expression of ITGA5 mRNA
CTD
PMID:35283115
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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Itgam
integrin subunit alpha M
multiple interactions increases expression
ISO EXP
Lidocaine inhibits the reaction [TNF protein results in increased expression of [ITGAM protein binds to ITGB2 protein]] Lidocaine results in increased expression of ITGAM mRNA
CTD
PMID:9336308 PMID:35283115
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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Itgax
integrin subunit alpha X
increases expression
EXP
Lidocaine results in increased expression of ITGAX mRNA
CTD
PMID:35283115
NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698
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Itgb2
integrin subunit beta 2
multiple interactions
ISO
Lidocaine inhibits the reaction [TNF protein results in increased expression of [ITGAM protein binds to ITGB2 protein]]
CTD
PMID:9336308
NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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Itsn1
intersectin 1
increases expression
EXP
Lidocaine results in increased expression of ITSN1 mRNA
CTD
PMID:35283115
NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645
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Izumo2
IZUMO family member 2
decreases expression
EXP
Lidocaine results in decreased expression of IZUMO2 mRNA
CTD
PMID:35283115
NCBI chr 1:95,196,459...95,209,131
Ensembl chr 1:95,196,459...95,209,092
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Jag1
jagged canonical Notch ligand 1
decreases expression
EXP
Lidocaine results in decreased expression of JAG1 mRNA
CTD
PMID:35283115
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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Kcnb2
potassium voltage-gated channel subfamily B member 2
decreases expression
EXP
Lidocaine results in decreased expression of KCNB2 mRNA
CTD
PMID:35283115
NCBI chr 5:3,567,012...4,028,564
Ensembl chr 5:3,569,685...4,028,599
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Kcnh2
potassium voltage-gated channel subfamily H member 2
decreases activity
ISO
Lidocaine results in decreased activity of KCNH2 protein
CTD
PMID:24052561
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Kcnk18
potassium two pore domain channel subfamily K member 18
multiple interactions
ISO
Lidocaine inhibits the reaction [KCNK18 protein results in increased transport of Potassium]
CTD
PMID:12754259
NCBI chr 1:258,374,671...258,388,945
Ensembl chr 1:258,374,671...258,388,945
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Kcnk9
potassium two pore domain channel subfamily K member 9
multiple interactions
EXP
Lidocaine inhibits the reaction [KCNK9 protein results in increased transport of Potassium]
CTD
PMID:10734076
NCBI chr 7:104,429,186...104,473,924
Ensembl chr 7:104,437,934...104,473,175
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Kcnn4
potassium calcium-activated channel subfamily N member 4
increases expression
EXP
Lidocaine results in increased expression of KCNN4 mRNA
CTD
PMID:35283115
NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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Kctd19
potassium channel tetramerization domain containing 19
decreases expression
EXP
Lidocaine results in decreased expression of KCTD19 mRNA
CTD
PMID:35283115
NCBI chr19:33,259,869...33,292,011
Ensembl chr19:33,259,970...33,292,006
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Kif11
kinesin family member 11
increases expression
EXP
Lidocaine results in increased expression of KIF11 mRNA
CTD
PMID:35283115
NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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Kif14
kinesin family member 14
increases expression
EXP
Lidocaine results in increased expression of KIF14 mRNA
CTD
PMID:35283115
NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
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Kif18a
kinesin family member 18A
increases expression
EXP
Lidocaine results in increased expression of KIF18A mRNA
CTD
PMID:35283115
NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582
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Kif18b
kinesin family member 18B
increases expression
EXP
Lidocaine results in increased expression of KIF18B mRNA
CTD
PMID:35283115
NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850
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Kif20a
kinesin family member 20A
increases expression
EXP
Lidocaine results in increased expression of KIF20A mRNA
CTD
PMID:35283115
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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Kif22
kinesin family member 22
increases expression
EXP
Lidocaine results in increased expression of KIF22 mRNA
CTD
PMID:35283115
NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
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Kif28
kinesin family member 28
decreases expression
EXP
Lidocaine results in decreased expression of KIF28P mRNA
CTD
PMID:35283115
NCBI chr13:91,427,527...91,482,297
Ensembl chr13:91,427,736...91,482,237
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Kifc1
kinesin family member C1
increases expression
EXP
Lidocaine results in increased expression of KIFC1 mRNA
CTD
PMID:35283115
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
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Klc1
kinesin light chain 1
decreases expression
EXP
Lidocaine results in decreased expression of KLC1 mRNA
CTD
PMID:35283115
NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031
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Klhl38
kelch-like family member 38
increases expression
EXP
Lidocaine results in increased expression of KLHL38 mRNA
CTD
PMID:35283115
NCBI chr 7:89,854,015...89,864,352
Ensembl chr 7:89,855,148...89,864,276
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Klhl6
kelch-like family member 6
increases expression
EXP
Lidocaine results in increased expression of KLHL6 mRNA
CTD
PMID:35283115
NCBI chr11:80,970,917...81,010,593
Ensembl chr11:80,970,917...81,009,677
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Kmo
kynurenine 3-monooxygenase
increases expression
EXP
Lidocaine results in increased expression of KMO mRNA
CTD
PMID:35283115
NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
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Kng1
kininogen 1
multiple interactions decreases activity
ISO
Lidocaine inhibits the reaction [[Propofol co-treated with Pharmaceutical Vehicles] results in increased expression of KNG1 protein modified form] Lidocaine results in decreased activity of KNG1 protein
CTD
PMID:1371395 PMID:10655909
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Knstrn
kinetochore-localized astrin/SPAG5 binding protein
increases expression
EXP
Lidocaine results in increased expression of KNSTRN mRNA
CTD
PMID:35283115
NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
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Kntc1
kinetochore associated 1
increases expression
EXP
Lidocaine results in increased expression of KNTC1 mRNA
CTD
PMID:35283115
NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561
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Kpna2
karyopherin subunit alpha 2
increases expression
EXP
Lidocaine results in increased expression of KPNA2 mRNA
CTD
PMID:35283115
NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
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Kpna7
karyopherin subunit alpha 7
decreases expression
EXP
Lidocaine results in decreased expression of KPNA7 mRNA
CTD
PMID:35283115
NCBI chr12:9,576,378...9,635,247
Ensembl chr12:9,576,378...9,612,833
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Krt34
keratin 34
decreases expression
EXP
Lidocaine results in decreased expression of KRT34 mRNA
CTD
PMID:35283115
NCBI chr10:84,969,988...84,974,098
Ensembl chr10:84,970,017...84,974,040
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Krt8
keratin 8
increases expression
EXP
Lidocaine results in increased expression of KRT8 mRNA
CTD
PMID:35283115
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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Lalba
lactalbumin, alpha
decreases expression
EXP
Lidocaine results in decreased expression of LALBA mRNA
CTD
PMID:35283115
NCBI chr 7:129,625,531...129,628,034
Ensembl chr 7:129,625,535...129,628,061
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Laptm5
lysosomal protein transmembrane 5
increases expression
EXP
Lidocaine results in increased expression of LAPTM5 mRNA
CTD
PMID:35283115
NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
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Lcp1
lymphocyte cytosolic protein 1
increases expression
EXP
Lidocaine results in increased expression of LCP1 mRNA
CTD
PMID:35283115
NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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Lcp2
lymphocyte cytosolic protein 2
increases expression
EXP
Lidocaine results in increased expression of LCP2 mRNA
CTD
PMID:35283115
NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559
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Lgals1
galectin 1
decreases expression
ISO
Lidocaine results in decreased expression of LGALS1 protein
CTD
PMID:18382663
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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Lgals12
galectin 12
decreases expression
EXP
Lidocaine results in decreased expression of LGALS12 mRNA
CTD
PMID:35283115
NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759
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Lgals3bp
galectin 3 binding protein
increases expression
EXP
Lidocaine results in increased expression of LGALS3BP mRNA
CTD
PMID:35283115
NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
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Lilrc2
leukocyte immunoglobulin-like receptor, subfamily C, member 2
decreases expression
EXP
Lidocaine results in decreased expression of LILRC2 mRNA
CTD
PMID:35283115
NCBI chr 1:65,272,134...65,277,278
Ensembl chr 1:65,272,796...65,277,271
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Limk2
LIM domain kinase 2
increases expression
EXP
Lidocaine results in increased expression of LIMK2 mRNA
CTD
PMID:35283115
NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007
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Lpl
lipoprotein lipase
increases expression
EXP
Lidocaine results in increased expression of LPL mRNA
CTD
PMID:35283115
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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Lpxn
leupaxin
increases expression
EXP
Lidocaine results in increased expression of LPXN mRNA
CTD
PMID:35283115
NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
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Lrr1
leucine rich repeat protein 1
increases expression
EXP
Lidocaine results in increased expression of LRR1 mRNA
CTD
PMID:35283115
NCBI chr 6:87,643,195...87,651,894
Ensembl chr 6:87,643,217...87,651,894
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Lrrc8e
leucine rich repeat containing 8 VRAC subunit E
increases expression
EXP
Lidocaine results in increased expression of LRRC8E mRNA
CTD
PMID:35283115
NCBI chr12:2,578,240...2,589,407
Ensembl chr12:2,578,315...2,589,412
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Lsm2
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
increases expression
EXP
Lidocaine results in increased expression of LSM2 mRNA
CTD
PMID:35283115
NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266
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Lst1
leukocyte specific transcript 1
increases expression
EXP
Lidocaine results in increased expression of LST1 mRNA
CTD
PMID:35283115
NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
G
Ly49i9
Ly49 inhibitory receptor 9
increases expression
EXP
Lidocaine results in increased expression of LY49I9 mRNA
CTD
PMID:35283115
G
Ly49s7
Ly49 stimulatory receptor 7
increases expression
EXP
Lidocaine results in increased expression of LY49S7 mRNA
CTD
PMID:35283115
NCBI chr 4:164,761,847...164,779,735
Ensembl chr 4:164,761,855...164,779,735
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Lyl1
LYL1, basic helix-loop-helix family member
increases expression
EXP
Lidocaine results in increased expression of LYL1 mRNA
CTD
PMID:35283115
NCBI chr19:23,452,140...23,455,007
Ensembl chr19:23,452,140...23,455,007
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Mad2l1
mitotic arrest deficient 2 like 1
increases expression
EXP
Lidocaine results in increased expression of MAD2L1 mRNA
CTD
PMID:35283115
NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
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Mageb11l1
MAGE family member B11 like 1
decreases expression
EXP
Lidocaine results in decreased expression of MAGEB11L1 mRNA
CTD
PMID:35283115
NCBI chr X:56,619,858...56,621,033
Ensembl chr X:56,619,985...56,621,013
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Malrd1
MAM and LDL receptor class A domain containing 1
increases expression
EXP
Lidocaine results in increased expression of MALRD1 mRNA
CTD
PMID:35283115
NCBI chr17:78,418,819...79,131,015
Ensembl chr17:78,418,819...79,131,016
G
Man2b1
mannosidase, alpha, class 2B, member 1
increases expression
EXP
Lidocaine results in increased expression of MAN2B1 mRNA
CTD
PMID:35283115
NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
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Man2b2
mannosidase, alpha, class 2B, member 2
increases expression
EXP
Lidocaine results in increased expression of MAN2B2 mRNA
CTD
PMID:35283115
NCBI chr14:73,969,079...73,994,089
Ensembl chr14:73,969,003...74,004,281
G
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
increases expression multiple interactions
EXP
Lidocaine results in increased expression of MAP1LC3A protein bafilomycin A1 inhibits the reaction [Lidocaine results in increased expression of MAP1LC3A protein]; dorsomorphin inhibits the reaction [Lidocaine results in increased expression of MAP1LC3A protein]; MK-8722 promotes the reaction [Lidocaine results in increased expression of MAP1LC3A protein]
CTD
PMID:37914286
NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
G
Map4k1
mitogen activated protein kinase kinase kinase kinase 1
increases expression
EXP
Lidocaine results in increased expression of MAP4K1 mRNA
CTD
PMID:35283115
NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
EXP
Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD
PMID:12196597
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
EXP
Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:12196597
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mastl
microtubule associated serine/threonine kinase-like
increases expression
EXP
Lidocaine results in increased expression of MASTL mRNA
CTD
PMID:35283115
NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
G
Mbp
myelin basic protein
decreases expression multiple interactions
EXP
Lidocaine results in decreased expression of MBP mRNA; Lidocaine results in decreased expression of MBP protein [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MBP mRNA]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MBP protein]
CTD
PMID:33166664
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
G
Mcl1
MCL1 apoptosis regulator, BCL2 family member
increases expression
EXP
Lidocaine results in increased expression of MCL1 mRNA
CTD
PMID:35283115
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
G
Mcm10
minichromosome maintenance 10 replication initiation factor
increases expression
EXP
Lidocaine results in increased expression of MCM10 mRNA
CTD
PMID:35283115
NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
G
Mcm2
minichromosome maintenance complex component 2
increases expression
EXP
Lidocaine results in increased expression of MCM2 mRNA
CTD
PMID:35283115
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
G
Mcm3
minichromosome maintenance complex component 3
increases expression
EXP
Lidocaine results in increased expression of MCM3 mRNA
CTD
PMID:35283115
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
G
Mcm4
minichromosome maintenance complex component 4
increases expression
EXP
Lidocaine results in increased expression of MCM4 mRNA
CTD
PMID:35283115
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
G
Mcm5
minichromosome maintenance complex component 5
increases expression
EXP
Lidocaine results in increased expression of MCM5 mRNA
CTD
PMID:35283115
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
G
Mcm6
minichromosome maintenance complex component 6
increases expression
EXP
Lidocaine results in increased expression of MCM6 mRNA
CTD
PMID:35283115
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
G
Meox1
mesenchyme homeobox 1
decreases expression
EXP
Lidocaine results in decreased expression of MEOX1 mRNA
CTD
PMID:35283115
NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
G
Mertk
MER proto-oncogene, tyrosine kinase
increases expression
EXP
Lidocaine results in increased expression of MERTK mRNA
CTD
PMID:35283115
NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
G
Milr1
mast cell immunoglobulin-like receptor 1
increases expression
EXP
Lidocaine results in increased expression of MILR1 mRNA
CTD
PMID:35283115
NCBI chr10:91,684,288...91,705,284
Ensembl chr10:91,687,831...91,705,282
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Mir199a2
microRNA 199a-2
multiple interactions increases expression
EXP
[Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MBP mRNA]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MBP protein]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MOG mRNA]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MYRF mRNA]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MYRF protein]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of PLP1 mRNA] Lidocaine results in increased expression of MIR199A2 mRNA
CTD
PMID:33166664
NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
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Mis18a
MIS18 kinetochore protein A
increases expression
EXP
Lidocaine results in increased expression of MIS18A mRNA
CTD
PMID:35283115
NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
G
Mis18bp1
MIS18 binding protein 1
increases expression
EXP
Lidocaine results in increased expression of MIS18BP1 mRNA
CTD
PMID:35283115
NCBI chr 6:83,182,497...83,231,978
Ensembl chr 6:83,182,499...83,231,383
G
Mlst8
MTOR associated protein, LST8 homolog
multiple interactions
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; dorsomorphin inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]; MK-8722 promotes the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]
CTD
PMID:37914286
NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
G
Mmp12
matrix metallopeptidase 12
increases expression
EXP
Lidocaine results in increased expression of MMP12 mRNA
CTD
PMID:35283115
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
G
Mmp3
matrix metallopeptidase 3
multiple interactions increases expression
EXP
cordycepin inhibits the reaction [Lidocaine results in increased expression of MMP3 mRNA]; cordycepin inhibits the reaction [Lidocaine results in increased expression of MMP3 protein] Lidocaine results in increased expression of MMP3 mRNA; Lidocaine results in increased expression of MMP3 protein
CTD
PMID:29382532
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
G
Mmp7
matrix metallopeptidase 7
increases expression
EXP
Lidocaine results in increased expression of MMP7 mRNA
CTD
PMID:35283115
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
G
Mms22l
MMS22-like, DNA repair protein
increases expression
EXP
Lidocaine results in increased expression of MMS22L mRNA
CTD
PMID:35283115
NCBI chr 5:38,197,707...38,313,745
Ensembl chr 5:38,197,779...38,313,745
G
Mobp
myelin-associated oligodendrocyte basic protein
decreases expression
EXP
Lidocaine results in decreased expression of MOBP mRNA
CTD
PMID:35283115
NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563
G
Mog
myelin oligodendrocyte glycoprotein
multiple interactions decreases expression
EXP
[Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MOG mRNA]
CTD
PMID:33166664
NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
G
Ms4a1
membrane spanning 4-domains A1
decreases expression
EXP
Lidocaine results in decreased expression of MS4A1 mRNA
CTD
PMID:35283115
NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512
G
Ms4a4a
membrane spanning 4-domains A4A
increases expression
EXP
Lidocaine results in increased expression of MS4A4A mRNA
CTD
PMID:35283115
NCBI chr 1:208,060,507...208,085,121
Ensembl chr 1:208,046,971...208,085,119
G
Ms4a6bl1
membrane-spanning 4-domains, subfamily A, member 6B-like 1
increases expression
EXP
Lidocaine results in increased expression of MS4A6BL1 mRNA
CTD
PMID:35283115
NCBI chr 1:208,243,561...208,255,400
Ensembl chr 1:208,243,559...208,257,340
G
Msr1
macrophage scavenger receptor 1
increases expression
EXP
Lidocaine results in increased expression of MSR1 mRNA
CTD
PMID:35283115
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
G
Msx3
msh homeobox 3
decreases expression
EXP
Lidocaine results in decreased expression of MSX3 mRNA
CTD
PMID:35283115
NCBI chr 1:194,839,041...194,842,209
Ensembl chr 1:194,839,041...194,841,969
G
Mtbp
MDM2 binding protein
increases expression
EXP
Lidocaine results in increased expression of MTBP mRNA
CTD
PMID:35283115
NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827
G
Mtor
mechanistic target of rapamycin kinase
multiple interactions
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; dorsomorphin inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]; MK-8722 promotes the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]
CTD
PMID:37914286
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Mug2
murinoglobulin 2
increases expression
EXP
Lidocaine results in increased expression of PZP mRNA
CTD
PMID:35283115
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
G
Mxd3
Max dimerization protein 3
increases expression
EXP
Lidocaine results in increased expression of MXD3 mRNA
CTD
PMID:35283115
NCBI chr17:9,301,430...9,305,156
Ensembl chr17:9,301,399...9,305,157
G
Mybl2
MYB proto-oncogene like 2
increases expression
EXP
Lidocaine results in increased expression of MYBL2 mRNA
CTD
PMID:35283115
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
G
Mybpc2
myosin binding protein C2
increases expression
EXP
Lidocaine results in increased expression of MYBPC2 mRNA
CTD
PMID:35283115
NCBI chr 1:94,994,121...95,017,584
Ensembl chr 1:94,994,104...95,017,584
G
Mylk3
myosin light chain kinase 3
increases expression
EXP
Lidocaine results in increased expression of MYLK3 mRNA
CTD
PMID:35283115
NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954
G
Myo18b
myosin XVIIIb
increases expression
EXP
Lidocaine results in increased expression of MYO18B mRNA
CTD
PMID:35283115
NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695
G
Myo1f
myosin IF
increases expression
EXP
Lidocaine results in increased expression of MYO1F mRNA
CTD
PMID:35283115
NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911
G
Myo7a
myosin VIIA
increases expression
EXP
Lidocaine results in increased expression of MYO7A mRNA
CTD
PMID:35283115
NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
G
Myrf
myelin regulatory factor
multiple interactions decreases expression
EXP
[Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MYRF mRNA]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MYRF protein] Lidocaine results in decreased expression of MYRF mRNA; Lidocaine results in decreased expression of MYRF protein
CTD
PMID:33166664
NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157
G
Naglu
N-acetyl-alpha-glucosaminidase
increases expression
EXP
Lidocaine results in increased expression of NAGLU mRNA
CTD
PMID:35283115
NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
G
Nav1
neuron navigator 1
decreases expression
EXP
Lidocaine results in decreased expression of NAV1 mRNA
CTD
PMID:35283115
NCBI chr13:46,866,972...47,119,368
Ensembl chr13:46,873,689...47,126,449
G
Ncan
neurocan
increases expression
EXP
Lidocaine results in increased expression of NCAN mRNA
CTD
PMID:35283115
NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
G
Ncapg
non-SMC condensin I complex, subunit G
increases expression
EXP
Lidocaine results in increased expression of NCAPG mRNA
CTD
PMID:35283115
NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
G
Ncapg2
non-SMC condensin II complex, subunit G2
increases expression
EXP
Lidocaine results in increased expression of NCAPG2 mRNA
CTD
PMID:35283115
NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159
G
Ncaph
non-SMC condensin I complex, subunit H
increases expression
EXP
Lidocaine results in increased expression of NCAPH mRNA
CTD
PMID:35283115
NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
G
Ncf1
neutrophil cytosolic factor 1
increases expression
EXP
Lidocaine results in increased expression of NCF1 mRNA
CTD
PMID:35283115
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
G
Nckap1l
NCK associated protein 1 like
increases expression
EXP
Lidocaine results in increased expression of NCKAP1L mRNA
CTD
PMID:35283115
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
G
Ndc80
NDC80 kinetochore complex component
increases expression
EXP
Lidocaine results in increased expression of NDC80 mRNA
CTD
PMID:35283115
NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
G
Nefm
neurofilament medium chain
multiple interactions decreases expression
ISO
NGF protein inhibits the reaction [Lidocaine results in decreased expression of NEFM protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of NEFM protein]
CTD
PMID:34193770
NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
G
Neil3
nei-like DNA glycosylase 3
increases expression
EXP
Lidocaine results in increased expression of NEIL3 mRNA
CTD
PMID:35283115
NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
G
Nek2
NIMA-related kinase 2
increases expression
EXP
Lidocaine results in increased expression of NEK2 mRNA
CTD
PMID:35283115
NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
G
Nes
nestin
increases expression
EXP
Lidocaine results in increased expression of NES mRNA
CTD
PMID:35283115
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
G
Nfasc
neurofascin
decreases expression
EXP
Lidocaine results in decreased expression of NFASC mRNA
CTD
PMID:35283115
NCBI chr13:43,997,223...44,183,863
Ensembl chr13:43,997,224...44,183,880
G
Nfe2
nuclear factor, erythroid 2
decreases expression
EXP
Lidocaine results in decreased expression of NFE2 mRNA
CTD
PMID:35283115
NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
G
Nfkbid
NFKB inhibitor delta
increases expression
EXP
Lidocaine results in increased expression of NFKBID mRNA
CTD
PMID:35283115
NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
G
Ngf
nerve growth factor
decreases expression multiple interactions
ISO
Lidocaine results in decreased expression of NGF protein NGF protein inhibits the reaction [Lidocaine results in decreased expression of NEFM protein]; NGF protein inhibits the reaction [Lidocaine results in decreased expression of NNAT protein]; NGF protein inhibits the reaction [Lidocaine results in decreased expression of UCHL1 protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of NGF protein] NGF protein inhibits the reaction [Lidocaine results in decreased expression of NEFM protein]; NGF protein inhibits the reaction [Lidocaine results in decreased expression of NNAT protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of NGF protein]
CTD
PMID:34193770
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
G
Ngfr
nerve growth factor receptor
increases expression
EXP
Lidocaine results in increased expression of NGFR mRNA
CTD
PMID:35283115
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
G
Nkain1
Sodium/potassium transporting ATPase interacting 1
increases expression
EXP
Lidocaine results in increased expression of NKAIN1 mRNA
CTD
PMID:35283115
NCBI chr 5:142,747,702...142,792,665
Ensembl chr 5:142,747,505...142,791,863
G
Nnat
neuronatin
multiple interactions decreases expression
ISO
NGF protein inhibits the reaction [Lidocaine results in decreased expression of NNAT protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of NEFM protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of NGF protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of UCHL1 protein]
CTD
PMID:34193770
NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity
ISO
Lidocaine results in increased activity of NR1I2 protein
CTD
PMID:25455453
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Nsl1
NSL1 component of MIS12 kinetochore complex
increases expression
EXP
Lidocaine results in increased expression of NSL1 mRNA
CTD
PMID:35283115
NCBI chr13:102,649,050...102,674,059
Ensembl chr13:102,649,058...102,674,054
G
Nt5dc2
5'-nucleotidase domain containing 2
increases expression
EXP
Lidocaine results in increased expression of NT5DC2 mRNA
CTD
PMID:35283115
NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537
G
Nuf2
NUF2 component of NDC80 kinetochore complex
increases expression
EXP
Lidocaine results in increased expression of NUF2 mRNA
CTD
PMID:35283115
NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
G
Nusap1
nucleolar and spindle associated protein 1
increases expression
EXP
Lidocaine results in increased expression of NUSAP1 mRNA
CTD
PMID:35283115
NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
G
Oasl
2'-5'-oligoadenylate synthetase-like
increases expression
EXP
Lidocaine results in increased expression of OASL mRNA
CTD
PMID:35283115
NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
G
Oip5
Opa interacting protein 5
increases expression
EXP
Lidocaine results in increased expression of OIP5 mRNA
CTD
PMID:35283115
NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250
G
Olr1
oxidized low density lipoprotein receptor 1
increases expression
EXP
Lidocaine results in increased expression of OLR1 mRNA
CTD
PMID:35283115
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
G
Oplah
5-oxoprolinase (ATP-hydrolysing)
increases expression
EXP
Lidocaine results in increased expression of OPLAH mRNA
CTD
PMID:35283115
NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297
G
Or10a48
olfactory receptor family 10 subfamily A member 48B
decreases expression
EXP
Lidocaine results in decreased expression of OR10A48 mRNA
CTD
PMID:35283115
NCBI chr 1:162,793,841...162,794,776
Ensembl chr 1:162,793,610...162,797,017
G
Or1x2c
olfactory receptor family 1 subfamily O member 2C
decreases expression
EXP
Lidocaine results in decreased expression of OR1X2C mRNA
CTD
PMID:35283115
NCBI chr10:35,364,667...35,365,608
Ensembl chr10:35,364,667...35,365,608
G
Or52e15c
olfactory receptor family 52 subfamily E member 15C
decreases expression
EXP
Lidocaine results in decreased expression of OR52E15C mRNA
CTD
PMID:35283115
NCBI chr 1:159,401,875...159,402,816
Ensembl chr 1:159,401,808...159,408,026
G
Or6k2
olfactory receptor family 6 subfamily K member 2
increases expression
EXP
Lidocaine results in increased expression of OR6K2 mRNA
CTD
PMID:35283115
NCBI chr13:86,186,442...86,190,391
Ensembl chr13:86,185,529...86,190,815
G
Or8g36b
olfactory receptor family 8 subfamily G member 36B
decreases expression
EXP
Lidocaine results in decreased expression of OR8G36B mRNA
CTD
PMID:35283115
NCBI chr 8:39,803,767...39,804,720
Ensembl chr 8:39,803,767...39,804,720
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Orc1
origin recognition complex, subunit 1
increases expression
EXP
Lidocaine results in increased expression of ORC1 mRNA
CTD
PMID:35283115
NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
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Orm1
orosomucoid 1
affects binding multiple interactions
ISO
Lidocaine binds to ORM1 protein alternative form Lidocaine inhibits the reaction [Warfarin binds to ORM1 protein alternative form]
CTD
PMID:8946472
NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
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Otulinl
OTU deubiquitinase with linear linkage specificity like
increases expression
EXP
Lidocaine results in increased expression of FAM105A mRNA
CTD
PMID:35283115
NCBI chr 2:78,405,994...78,433,860
Ensembl chr 2:78,408,593...78,433,838
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Ovch2
ovochymase 2
decreases expression
EXP
Lidocaine results in decreased expression of OVCH2 mRNA
CTD
PMID:35283115
NCBI chr 1:161,693,619...161,713,952
Ensembl chr 1:161,693,647...161,713,952
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Parp10
poly (ADP-ribose) polymerase family, member 10
increases expression
EXP
Lidocaine results in increased expression of PARP10 mRNA
CTD
PMID:35283115
NCBI chr 7:107,949,031...107,958,377
Ensembl chr 7:107,949,043...107,958,304
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Parp14
poly (ADP-ribose) polymerase family, member 14
increases expression
EXP
Lidocaine results in increased expression of PARP14 mRNA
CTD
PMID:35283115
NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916
G
Pcdh15
protocadherin related 15
decreases expression
EXP
Lidocaine results in decreased expression of PCDH15 mRNA
CTD
PMID:35283115
NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
G
Pcdha12
protocadherin alpha 12
increases expression
EXP
Lidocaine results in increased expression of PCDHA12 mRNA
CTD
PMID:35283115
Ensembl chr18:28,581,225...28,846,211
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Pclaf
PCNA clamp associated factor
increases expression
EXP
Lidocaine results in increased expression of PCLAF mRNA
CTD
PMID:35283115
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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Pdcd1
programmed cell death 1
increases expression
EXP
Lidocaine results in increased expression of PDCD1 mRNA
CTD
PMID:35283115
NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937
G
Pde6b
phosphodiesterase 6B
increases expression
EXP
Lidocaine results in increased expression of PDE6B mRNA
CTD
PMID:35283115
NCBI chr14:1,323,310...1,366,450
Ensembl chr14:1,323,310...1,366,450
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Pf4
platelet factor 4
increases expression
EXP
Lidocaine results in increased expression of PF4 mRNA
CTD
PMID:35283115
NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
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Pgap1
post-GPI attachment to proteins inositol deacylase 1
increases expression
EXP
Lidocaine results in increased expression of PGAP1 mRNA
CTD
PMID:35283115
NCBI chr 9:55,975,574...56,044,325
Ensembl chr 9:55,975,667...56,044,464
G
Phldb3
pleckstrin homology-like domain, family B, member 3
increases expression
EXP
Lidocaine results in increased expression of PHLDB3 mRNA
CTD
PMID:35283115
NCBI chr 1:80,201,083...80,219,541
Ensembl chr 1:80,201,578...80,219,534
G
Pi15
peptidase inhibitor 15
decreases expression
EXP
Lidocaine results in decreased expression of PI15 mRNA
CTD
PMID:35283115
NCBI chr 5:1,395,094...1,423,213
Ensembl chr 5:1,395,094...1,423,213
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
increases expression
EXP
Lidocaine results in increased expression of PIK3CG mRNA
CTD
PMID:35283115
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
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Pimreg
PICALM interacting mitotic regulator
increases expression
EXP
Lidocaine results in increased expression of FAM64A mRNA
CTD
PMID:35283115
NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791
G
Pink1
PTEN induced kinase 1
multiple interactions increases expression
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in increased expression of PINK1 protein]; dorsomorphin inhibits the reaction [Lidocaine results in increased expression of PINK1 protein]; MK-8722 promotes the reaction [Lidocaine results in increased expression of PINK1 protein]
CTD
PMID:37914286
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Pip
prolactin induced protein
increases expression
EXP
Lidocaine results in increased expression of PIP mRNA
CTD
PMID:35283115
NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921
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Pla2g2a
phospholipase A2 group IIA
decreases expression
EXP
Lidocaine results in decreased expression of PLA2G2A mRNA
CTD
PMID:35283115
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
G
Plac8
placenta associated 8
decreases expression
EXP
Lidocaine results in decreased expression of PLAC8 mRNA
CTD
PMID:35283115
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
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Plau
plasminogen activator, urokinase
increases expression
EXP
Lidocaine results in increased expression of PLAU mRNA
CTD
PMID:35283115
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Plaur
plasminogen activator, urokinase receptor
increases expression
EXP
Lidocaine results in increased expression of PLAUR mRNA
CTD
PMID:35283115
NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
G
Plbd1
phospholipase B domain containing 1
increases expression
EXP
Lidocaine results in increased expression of PLBD1 mRNA
CTD
PMID:35283115
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
G
Plcb2
phospholipase C, beta 2
increases expression
EXP
Lidocaine results in increased expression of PLCB2 mRNA
CTD
PMID:35283115
NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
G
Pld4
phospholipase D family, member 4
increases expression
EXP
Lidocaine results in increased expression of PLD4 mRNA
CTD
PMID:35283115
NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376
G
Plek2
pleckstrin 2
decreases expression
EXP
Lidocaine results in decreased expression of PLEK2 mRNA
CTD
PMID:35283115
NCBI chr 6:97,700,123...97,719,417
Ensembl chr 6:97,701,106...97,719,326
G
Plekha2
pleckstrin homology domain containing A2
increases expression
EXP
Lidocaine results in increased expression of PLEKHA2 mRNA
CTD
PMID:35283115
NCBI chr16:66,938,684...67,000,661
Ensembl chr16:66,939,109...66,999,395
G
Plin2
perilipin 2
increases expression
EXP
Lidocaine results in increased expression of PLIN2 mRNA
CTD
PMID:35283115
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Pln
phospholamban
decreases expression
EXP
Lidocaine results in decreased expression of PLN mRNA
CTD
PMID:35283115
NCBI chr20:32,629,537...32,639,559
G
Plp1
proteolipid protein 1
decreases expression multiple interactions
EXP
Lidocaine results in decreased expression of PLP1 mRNA [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of PLP1 mRNA]
CTD
PMID:33166664
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
G
Pm20d2
peptidase M20 domain containing 2
increases expression
EXP
Lidocaine results in increased expression of PM20D2 mRNA
CTD
PMID:35283115
NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212
G
Pmf1
polyamine-modulated factor 1
increases expression
EXP
Lidocaine results in increased expression of PMF1 mRNA
CTD
PMID:35283115
NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270
G
Pof1b
POF1B, actin binding protein
decreases expression
EXP
Lidocaine results in decreased expression of POF1B mRNA
CTD
PMID:35283115
NCBI chr X:77,683,128...77,749,827
Ensembl chr X:77,683,128...77,749,688
G
Pola1
DNA polymerase alpha 1, catalytic subunit
increases expression
EXP
Lidocaine results in increased expression of POLA1 mRNA
CTD
PMID:35283115
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
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Pole
DNA polymerase epsilon, catalytic subunit
increases expression
EXP
Lidocaine results in increased expression of POLE mRNA
CTD
PMID:35283115
NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
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Pole2
DNA polymerase epsilon 2, accessory subunit
increases expression
EXP
Lidocaine results in increased expression of POLE2 mRNA
CTD
PMID:35283115
NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
G
Polq
DNA polymerase theta
increases expression
EXP
Lidocaine results in increased expression of POLQ mRNA
CTD
PMID:35283115
NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
G
Pomc
proopiomelanocortin
multiple interactions
EXP
Lidocaine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]
CTD
PMID:8925284
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
G
Postn
periostin
increases expression
EXP
Lidocaine results in increased expression of POSTN mRNA
CTD
PMID:35283115
NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
G
Ppp4r3c
protein phosphatase 4 regulatory subunit 3C
decreases expression
EXP
Lidocaine results in decreased expression of PPP4R3C mRNA
CTD
PMID:35283115
NCBI chr X:53,630,250...53,722,658
G
Prc1
protein regulator of cytokinesis 1
increases expression
EXP
Lidocaine results in increased expression of PRC1 mRNA
CTD
PMID:35283115
NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
G
Primpol
primase and DNA directed polymerase
increases expression
EXP
Lidocaine results in increased expression of PRIMPOL mRNA
CTD
PMID:35283115
NCBI chr16:45,681,252...45,715,758
Ensembl chr16:45,681,326...45,715,565
G
Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
multiple interactions
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in increased phosphorylation of PRKAA1 protein]; dorsomorphin inhibits the reaction [Lidocaine results in increased phosphorylation of PRKAA1 protein]; MK-8722 promotes the reaction [Lidocaine results in increased phosphorylation of PRKAA1 protein]
CTD
PMID:37914286
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
G
Prkcb
protein kinase C, beta
increases expression multiple interactions
EXP
Lidocaine results in increased expression of PRKCB protein Dexmedetomidine inhibits the reaction [Lidocaine results in increased expression of PRKCB protein]
CTD
PMID:30240660
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
G
Prkcg
protein kinase C, gamma
multiple interactions
EXP
Lidocaine inhibits the reaction [remifentanil affects the localization of PRKCG protein]
CTD
PMID:19955894
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
G
Prok2
prokineticin 2
decreases expression
EXP
Lidocaine results in decreased expression of PROK2 mRNA
CTD
PMID:35283115
NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
G
Prph2
peripherin 2
decreases expression
EXP
Lidocaine results in decreased expression of PRPH2 mRNA
CTD
PMID:35283115
NCBI chr 9:14,066,149...14,081,454
Ensembl chr 9:14,066,156...14,081,454
G
Prr11
proline rich 11
increases expression
EXP
Lidocaine results in increased expression of PRR11 mRNA
CTD
PMID:35283115
NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012
G
Prrg4
proline rich and Gla domain 4
increases expression
EXP
Lidocaine results in increased expression of PRRG4 mRNA
CTD
PMID:35283115
NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
G
Prss56
serine protease 56
increases expression
EXP
Lidocaine results in increased expression of PRSS56 mRNA
CTD
PMID:35283115
NCBI chr 9:87,842,806...87,859,978
Ensembl chr 9:87,854,805...87,859,978
G
Ptges
prostaglandin E synthase
decreases expression
EXP
Lidocaine results in decreased expression of PTGES mRNA
CTD
PMID:35283115
NCBI chr 3:14,177,892...14,189,236
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
EXP
Lidocaine results in decreased expression of PTGS2 mRNA
CTD
PMID:35283115
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptpn18
protein tyrosine phosphatase, non-receptor type 18
increases expression
EXP
Lidocaine results in increased expression of PTPN18 mRNA
CTD
PMID:35283115
NCBI chr 9:36,672,325...36,689,963
Ensembl chr 9:36,672,362...36,690,995
G
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
increases expression
EXP
Lidocaine results in increased expression of PTPN6 mRNA
CTD
PMID:35283115
NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
G
Pttg1
PTTG1 regulator of sister chromatid separation, securin
increases expression
EXP
Lidocaine results in increased expression of PTTG1 mRNA
CTD
PMID:35283115
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
G
Ptx3
pentraxin 3
decreases expression
EXP
Lidocaine results in decreased expression of PTX3 mRNA
CTD
PMID:35283115
NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
G
Pvr
PVR cell adhesion molecule
increases expression
EXP
Lidocaine results in increased expression of PVR mRNA
CTD
PMID:35283115
NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
G
Pvt1
Pvt1 oncogene
increases expression
EXP
Lidocaine results in increased expression of PVT1 mRNA
CTD
PMID:35283115
NCBI chr 7:93,656,528...93,879,938
G
Pycard
PYD and CARD domain containing
increases expression
EXP
Lidocaine results in increased expression of PYCARD mRNA
CTD
PMID:35283115
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
G
Pyy
peptide YY
increases expression
EXP
Lidocaine results in increased expression of PYY mRNA
CTD
PMID:35283115
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
G
Qprt
quinolinate phosphoribosyltransferase
increases expression
EXP
Lidocaine results in increased expression of QPRT mRNA
CTD
PMID:35283115
NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
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Rab7b
Rab7b, member RAS oncogene family
increases expression
EXP
Lidocaine results in increased expression of RAB7B mRNA
CTD
PMID:35283115
NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
G
Rab8a
RAB8A, member RAS oncogene family
increases expression
EXP
Lidocaine results in increased expression of RAB8A mRNA
CTD
PMID:35283115
NCBI chr16:17,654,027...17,675,385
Ensembl chr16:17,654,034...17,675,678
G
Racgap1
Rac GTPase-activating protein 1
increases expression
EXP
Lidocaine results in increased expression of RACGAP1 mRNA
CTD
PMID:35283115
NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
G
Rad51
RAD51 recombinase
increases expression
EXP
Lidocaine results in increased expression of RAD51 mRNA
CTD
PMID:35283115
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
G
Rad54l
RAD54 like
increases expression
EXP
Lidocaine results in increased expression of RAD54L mRNA
CTD
PMID:35283115
NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
G
Rasa4
RAS p21 protein activator 4
increases expression
EXP
Lidocaine results in increased expression of RASA4 mRNA
CTD
PMID:35283115
NCBI chr12:20,552,805...20,580,177
Ensembl chr12:20,552,806...20,580,147
G
Rbl1
RB transcriptional corepressor like 1
affects expression increases expression
ISO EXP
Lidocaine affects the expression of RBL1 mRNA Lidocaine results in increased expression of RBL1 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
G
Rbl2
RB transcriptional corepressor like 2
affects expression
ISO
Lidocaine affects the expression of RBL2 mRNA
CTD
PMID:18931217
NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
G
Rbm47
RNA binding motif protein 47
increases expression
EXP
Lidocaine results in increased expression of RBM47 mRNA
CTD
PMID:35283115
NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431
G
Recql4
RecQ like helicase 4
increases expression
EXP
Lidocaine results in increased expression of RECQL4 mRNA
CTD
PMID:35283115
NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
G
Reg3b
regenerating family member 3 beta
increases expression
EXP
Lidocaine results in increased expression of REG3B mRNA
CTD
PMID:35283115
NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
G
RGD1559545
similar to ATPase inhibitory factor 1
decreases expression
EXP
Lidocaine results in decreased expression of RGD1559545 mRNA
CTD
PMID:35283115
NCBI chr 6:89,821,916...89,842,882
G
RGD1560225
similar to nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
increases expression
EXP
Lidocaine results in increased expression of RGD1560225 mRNA
CTD
PMID:35283115
G
Rgs18
regulator of G-protein signaling 18
increases expression
EXP
Lidocaine results in increased expression of RGS18 mRNA
CTD
PMID:35283115
NCBI chr13:56,493,134...56,516,045
Ensembl chr13:56,494,010...56,516,098
G
Rn28s
28S ribosomal RNA
decreases expression
EXP
Lidocaine results in decreased expression of RN28S mRNA
CTD
PMID:35283115
G
Rptor
regulatory associated protein of MTOR, complex 1
multiple interactions
EXP
bafilomycin A1 inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; dorsomorphin inhibits the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]; Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]; MK-8722 promotes the reaction [Lidocaine results in decreased expression of [MTOR protein binds to RPTOR protein binds to MLST8 protein binds to PRAS40 protein binds to DEPTOR protein]]
CTD
PMID:37914286
NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
G
Rrm1
ribonucleotide reductase catalytic subunit M1
increases expression
EXP
Lidocaine results in increased expression of RRM1 mRNA
CTD
PMID:35283115
NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
G
Rrm2
ribonucleotide reductase regulatory subunit M2
increases expression
EXP
Lidocaine results in increased expression of RRM2 mRNA
CTD
PMID:35283115
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
G
Rsad2
radical S-adenosyl methionine domain containing 2
increases expression
EXP
Lidocaine results in increased expression of RSAD2 mRNA
CTD
PMID:35283115
NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
G
RT1-CE10
RT1 class I, locus CE10
decreases expression
EXP
Lidocaine results in decreased expression of RT1-CE10 mRNA
CTD
PMID:35283115
NCBI chr20:3,377,284...3,380,301
G
RT1-CE2
RT1 class I, locus CE2
decreases expression
EXP
Lidocaine results in decreased expression of RT1-CE2 mRNA
CTD
PMID:35283115
NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
G
RT1-CE5
RT1 class I, locus CE5
decreases expression
EXP
Lidocaine results in decreased expression of RT1-CE5 mRNA
CTD
PMID:35283115
NCBI chr20:3,403,418...3,479,476
G
RT1-DMb
RT1 class II, locus DMb
increases expression
EXP
Lidocaine results in increased expression of RT1-DMB mRNA
CTD
PMID:35283115
NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
G
RT1-N2
RT1 class Ib, locus N2
increases expression
EXP
Lidocaine results in increased expression of RT1-N2 mRNA
CTD
PMID:35283115
NCBI chr20:2,641,157...2,645,439
Ensembl chr20:2,641,202...2,644,900
G
RT1-T24-3
RT1 class I, locus T24, gene 3
increases expression
EXP
Lidocaine results in increased expression of RT1-T24-3 mRNA
CTD
PMID:35283115
NCBI chr20:2,718,210...2,730,604
Ensembl chr20:2,718,279...2,776,154
G
S100a11
S100 calcium binding protein A11
increases expression
EXP
Lidocaine results in increased expression of S100A11 mRNA
CTD
PMID:35283115
NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
G
S100a3
S100 calcium binding protein A3
increases expression
EXP
Lidocaine results in increased expression of S100A3 mRNA
CTD
PMID:35283115
NCBI chr 2:176,034,283...176,089,702
Ensembl chr 2:176,049,520...176,089,702
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S100a8
S100 calcium binding protein A8
increases expression decreases expression
ISO EXP
Lidocaine results in increased expression of S100A8 protein Lidocaine results in decreased expression of S100A8 mRNA
CTD
PMID:18382663 PMID:35283115
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
increases expression
ISO
Lidocaine results in increased expression of S100A9 protein
CTD
PMID:18382663
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Sapcd2
suppressor APC domain containing 2
increases expression
EXP
Lidocaine results in increased expression of SAPCD2 mRNA
CTD
PMID:35283115
NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546
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Sc5d
sterol-C5-desaturase
decreases expression
EXP
Lidocaine results in decreased expression of SC5D mRNA
CTD
PMID:35283115
NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
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Scgb1a1
secretoglobin family 1A member 1
increases expression
EXP
Lidocaine results in increased expression of SCGB1A1 mRNA
CTD
PMID:35283115
NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
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Scn4a
sodium voltage-gated channel alpha subunit 4
multiple interactions
ISO
Lidocaine binds to and results in decreased activity of SCN4A protein
CTD
PMID:14662728
NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545
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Scn5a
sodium voltage-gated channel alpha subunit 5
affects response to substance
ISO
SCN5A protein mutant form affects the susceptibility to Lidocaine
CTD
PMID:18599870
NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
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Sct
secretin
increases expression
EXP
Lidocaine results in increased expression of SCT mRNA
CTD
PMID:35283115
NCBI chr 1:196,382,857...196,383,668
Ensembl chr 1:196,382,856...196,383,658
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Scube1
signal peptide, CUB domain and EGF like domain containing 1
increases expression
EXP
Lidocaine results in increased expression of SCUBE1 mRNA
CTD
PMID:35283115
NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940
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Sdf2l1
stromal cell-derived factor 2-like 1
increases expression
EXP
Lidocaine results in increased expression of SDF2L1 mRNA
CTD
PMID:35283115
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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Sell
selectin L
multiple interactions
ISO
Lidocaine inhibits the reaction [TNF protein results in increased cleavage of SELL protein]
CTD
PMID:9336308
NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
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Sema5b
semaphorin 5B
increases expression
EXP
Lidocaine results in increased expression of SEMA5B mRNA
CTD
PMID:35283115
NCBI chr11:65,102,532...65,225,456
Ensembl chr11:65,102,031...65,225,311
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Sgo2
shugoshin 2
increases expression
EXP
Lidocaine results in increased expression of SGO2 mRNA
CTD
PMID:35283115
NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229
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Sgsm3
small G protein signaling modulator 3
decreases expression
EXP
Lidocaine results in decreased expression of SGSM3 mRNA
CTD
PMID:35283115
NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:112,514,630...112,544,108
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Shc4
SHC adaptor protein 4
increases expression
EXP
Lidocaine results in increased expression of SHC4 mRNA
CTD
PMID:35283115
NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:112,880,600...112,974,366
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Shcbp1
SHC binding and spindle associated 1
increases expression
EXP
Lidocaine results in increased expression of SHCBP1 mRNA
CTD
PMID:35283115
NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
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Shmt1
serine hydroxymethyltransferase 1
increases expression
EXP
Lidocaine results in increased expression of SHMT1 mRNA
CTD
PMID:35283115
NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820
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Sirt4
sirtuin 4
decreases expression
EXP
Lidocaine results in decreased expression of SIRT4 mRNA
CTD
PMID:35283115
NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
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Ska1
spindle and kinetochore associated complex subunit 1
increases expression
EXP
Lidocaine results in increased expression of SKA1 mRNA
CTD
PMID:35283115
NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037
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Ska3
spindle and kinetochore associated complex subunit 3
increases expression
EXP
Lidocaine results in increased expression of SKA3 mRNA
CTD
PMID:35283115
NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
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Slamf7
SLAM family member 7
increases expression
EXP
Lidocaine results in increased expression of SLAMF7 mRNA
CTD
PMID:35283115
NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105
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Slamf9
SLAM family member 9
increases expression
EXP
Lidocaine results in increased expression of SLAMF9 mRNA
CTD
PMID:35283115
NCBI chr13:84,941,896...84,944,749
Ensembl chr13:84,941,982...84,944,748
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Slc10a6
solute carrier family 10 member 6
increases expression
EXP
Lidocaine results in increased expression of SLC10A6 mRNA
CTD
PMID:35283115
NCBI chr14:6,080,716...6,102,902
Ensembl chr14:6,080,717...6,103,037
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Slc13a3
solute carrier family 13 member 3
decreases expression
EXP
Lidocaine results in decreased expression of SLC13A3 mRNA
CTD
PMID:35283115
NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
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Slc22a1
solute carrier family 22 member 1
multiple interactions
ISO
Lidocaine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
CTD
PMID:21641380
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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Slc22a16
solute carrier family 22 member 16
multiple interactions
ISO
Lidocaine inhibits the reaction [SLC22A16 protein results in increased uptake of Tetraethylammonium]
CTD
PMID:15963465
NCBI chr20:43,972,808...44,068,447
Ensembl chr20:43,972,836...44,065,019
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
Lidocaine inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium]
CTD
PMID:23770354
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Slc22a3
solute carrier family 22 member 3
multiple interactions
ISO
Lidocaine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
CTD
PMID:21641380
NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
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Slc22a4
solute carrier family 22 member 4
multiple interactions
ISO
Lidocaine inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium]
CTD
PMID:21641380
NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
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Slc22a5
solute carrier family 22 member 5
multiple interactions
ISO
Lidocaine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]
CTD
PMID:21641380
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
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Slc26a2
solute carrier family 26 member 2
decreases expression
EXP
Lidocaine results in decreased expression of SLC26A2 mRNA
CTD
PMID:35283115
NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626
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Slc28a1
solute carrier family 28 member 1
decreases expression
EXP
Lidocaine results in decreased expression of SLC28A1 mRNA
CTD
PMID:35283115
NCBI chr 1:135,079,375...135,122,791
Ensembl chr 1:135,081,385...135,122,464
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Slc39a12
solute carrier family 39 member 12
increases expression
EXP
Lidocaine results in increased expression of SLC39A12 mRNA
CTD
PMID:35283115
NCBI chr17:77,353,761...77,440,384
Ensembl chr17:77,353,805...77,440,353
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Slc41a2
solute carrier family 41 member 2
decreases expression
EXP
Lidocaine results in decreased expression of SLC41A2 mRNA
CTD
PMID:35283115
NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
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Slc6a2
solute carrier family 6 member 2
multiple interactions
ISO
Lidocaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine]
CTD
PMID:16725121
NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
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Slc7a7
solute carrier family 7 member 7
increases expression
EXP
Lidocaine results in increased expression of SLC7A7 mRNA
CTD
PMID:35283115
NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648
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Slco2b1
solute carrier organic anion transporter family, member 2b1
increases expression
EXP
Lidocaine results in increased expression of SLCO2B1 mRNA
CTD
PMID:35283115
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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Smc2
structural maintenance of chromosomes 2
increases expression
EXP
Lidocaine results in increased expression of SMC2 mRNA
CTD
PMID:35283115
NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242
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Snx20
sorting nexin 20
increases expression
EXP
Lidocaine results in increased expression of SNX20 mRNA
CTD
PMID:35283115
NCBI chr19:18,435,935...18,445,108
Ensembl chr19:18,435,935...18,445,107
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Soat1
sterol O-acyltransferase 1
increases expression
EXP
Lidocaine results in increased expression of SOAT1 mRNA
CTD
PMID:35283115
NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
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SPATA45
spermatogenesis associated 45
increases expression
EXP
Lidocaine results in increased expression of PYHIN1 mRNA
CTD
PMID:35283115
NCBI chr13:102,624,298...102,631,191
Ensembl chr13:102,625,273...102,631,191
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Spc24
SPC24 component of NDC80 kinetochore complex
increases expression
EXP
Lidocaine results in increased expression of SPC24 mRNA
CTD
PMID:35283115
NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310
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Spc25
SPC25 component of NDC80 kinetochore complex
increases expression
EXP
Lidocaine results in increased expression of SPC25 mRNA
CTD
PMID:35283115
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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Spi1
Spi-1 proto-oncogene
increases expression
EXP
Lidocaine results in increased expression of SPI1 mRNA
CTD
PMID:35283115
NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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Spink2
serine peptidase inhibitor, Kazal type 2
increases expression
EXP
Lidocaine results in increased expression of SPINK2 mRNA
CTD
PMID:35283115
NCBI chr14:30,967,682...30,974,326
Ensembl chr14:30,967,714...30,974,326
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Spp1
secreted phosphoprotein 1
increases expression
EXP
Lidocaine results in increased expression of SPP1 mRNA
CTD
PMID:35283115
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Srd5a2
steroid 5 alpha-reductase 2
decreases expression
EXP
Lidocaine results in decreased expression of SRD5A2 mRNA
CTD
PMID:35283115
NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
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St14
ST14 transmembrane serine protease matriptase
increases expression
EXP
Lidocaine results in increased expression of ST14 mRNA
CTD
PMID:35283115
NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
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Stap1
signal transducing adaptor family member 1
increases expression
EXP
Lidocaine results in increased expression of STAP1 mRNA
CTD
PMID:35283115
NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245
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Stat6
signal transducer and activator of transcription 6
increases expression
EXP
Lidocaine results in increased expression of STAT6 mRNA
CTD
PMID:35283115
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
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Steap4
STEAP4 metalloreductase
decreases expression
EXP
Lidocaine results in decreased expression of STEAP4 mRNA
CTD
PMID:35283115
NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
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Stfa2l3
stefin A2-like 3
decreases expression
EXP
Lidocaine results in decreased expression of STFA2L3 mRNA
CTD
PMID:35283115
NCBI chr11:64,588,401...64,593,418
Ensembl chr11:64,588,465...64,593,327
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Stfa3l1
stefin A3-like 1
decreases expression
EXP
Lidocaine results in decreased expression of STFA3L1 mRNA
CTD
PMID:35283115
NCBI chr11:64,608,683...64,615,902
Ensembl chr11:64,608,683...64,615,902
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Stil
STIL, centriolar assembly protein
increases expression
EXP
Lidocaine results in increased expression of STIL mRNA
CTD
PMID:35283115
NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
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Stkld1
serine/threonine kinase-like domain containing 1
decreases expression
EXP
Lidocaine results in decreased expression of STKLD1 mRNA
CTD
PMID:35283115
NCBI chr 3:10,261,583...10,280,850
Ensembl chr 3:10,261,828...10,280,566
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Stmn1
stathmin 1
increases expression
EXP
Lidocaine results in increased expression of STMN1 mRNA; Lidocaine results in increased expression of STMN1 protein
CTD
PMID:27018092
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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Stxbp2
syntaxin binding protein 2
increases expression
EXP
Lidocaine results in increased expression of STXBP2 mRNA
CTD
PMID:35283115
NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
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Sult1a1
sulfotransferase family 1A member 1
increases sulfation
ISO
SULT1A1 protein results in increased sulfation of Lidocaine metabolite
CTD
PMID:10460806
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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Sult1b1
sulfotransferase family 1B member 1
increases sulfation
ISO
SULT1B1 protein results in increased sulfation of Lidocaine metabolite
CTD
PMID:10460806
NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
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Syk
spleen associated tyrosine kinase
increases expression
EXP
Lidocaine results in increased expression of SYK mRNA
CTD
PMID:35283115
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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Sypl2
synaptophysin-like 2
increases expression
EXP
Lidocaine results in increased expression of SYPL2 mRNA
CTD
PMID:35283115
NCBI chr 2:195,849,062...195,863,794
Ensembl chr 2:195,849,062...195,863,794
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Tac1
tachykinin, precursor 1
increases expression
EXP
Lidocaine results in increased expression of TAC1 mRNA
CTD
PMID:35283115
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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Tacc3
transforming, acidic coiled-coil containing protein 3
increases expression
EXP
Lidocaine results in increased expression of TACC3 mRNA
CTD
PMID:35283115
NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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Tagap
T-cell activation RhoGTPase activating protein
increases expression
EXP
Lidocaine results in increased expression of TAGAP mRNA
CTD
PMID:35283115
NCBI chr 1:47,170,725...47,179,705
Ensembl chr 1:47,170,725...47,179,792
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Tcf19
transcription factor 19
increases expression
EXP
Lidocaine results in increased expression of TCF19 mRNA
CTD
PMID:35283115
NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271
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Tchhl1
trichohyalin-like 1
decreases expression
EXP
Lidocaine results in decreased expression of TCHHL1 mRNA
CTD
PMID:35283115
NCBI chr 2:179,134,941...179,138,467
Ensembl chr 2:179,135,796...179,138,202
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Tcim
transcriptional and immune response regulator
increases expression
EXP
Lidocaine results in increased expression of TCIM mRNA
CTD
PMID:35283115
NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
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Tec
tec protein tyrosine kinase
increases expression
EXP
Lidocaine results in increased expression of TEC mRNA
CTD
PMID:35283115
NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
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Tent5a
terminal nucleotidyltransferase 5A
increases expression
EXP
Lidocaine results in increased expression of FAM46A mRNA
CTD
PMID:35283115
NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045
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Tent5c
terminal nucleotidyltransferase 5C
increases expression
EXP
Lidocaine results in increased expression of FAM46C mRNA
CTD
PMID:35283115
NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
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Tex56p
testis expressed 56
increases expression
EXP
Lidocaine results in increased expression of TEX56P mRNA
CTD
PMID:35283115
NCBI chr17:29,929,855...29,966,578
Ensembl chr17:29,929,780...29,966,579
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Tff3
trefoil factor 3
increases expression
EXP
Lidocaine results in increased expression of TFF3 mRNA
CTD
PMID:35283115
NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
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Tgfa
transforming growth factor alpha
decreases expression
ISO
Lidocaine results in decreased expression of TGFA protein
CTD
PMID:18382663
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Tgfb1
transforming growth factor, beta 1
increases expression
EXP
Lidocaine results in increased expression of TGFB1 mRNA
CTD
PMID:35283115
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgif2
TGFB-induced factor homeobox 2
increases expression
EXP
Lidocaine results in increased expression of TGIF2 mRNA
CTD
PMID:35283115
NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596 Ensembl chr17:145,333,418...145,348,596
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Thbs2
thrombospondin 2
increases expression
EXP
Lidocaine results in increased expression of THBS2 mRNA
CTD
PMID:35283115
NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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Thbs4
thrombospondin 4
increases expression
EXP
Lidocaine results in increased expression of THBS4 mRNA
CTD
PMID:35283115
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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Ticam2
TIR domain containing adaptor molecule 2
increases expression
EXP
Lidocaine results in increased expression of TICAM2 mRNA
CTD
PMID:35283115
NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
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Ticrr
TOPBP1-interacting checkpoint and replication regulator
increases expression
EXP
Lidocaine results in increased expression of TICRR mRNA
CTD
PMID:35283115
NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523
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Tifab
TIFA inhibitor
increases expression
EXP
Lidocaine results in increased expression of TIFAB mRNA
CTD
PMID:35283115
NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592
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Timd2
T-cell immunoglobulin and mucin domain containing 2
increases expression
EXP
Lidocaine results in increased expression of TIMD2 mRNA
CTD
PMID:35283115
NCBI chr10:31,060,308...31,101,262
Ensembl chr10:31,060,326...31,094,623
G
Tk1
thymidine kinase 1
increases expression
EXP
Lidocaine results in increased expression of TK1 mRNA
CTD
PMID:35283115
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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Tln1
talin 1
increases expression
EXP
Lidocaine results in increased expression of TLN1 mRNA
CTD
PMID:35283115
NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900
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Tlr3
toll-like receptor 3
increases expression
EXP
Lidocaine results in increased expression of TLR3 mRNA
CTD
PMID:35283115
NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
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Tlr4
toll-like receptor 4
increases expression
EXP
Lidocaine results in increased expression of TLR4 mRNA
CTD
PMID:35283115
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tlr8
toll-like receptor 8
increases expression
EXP
Lidocaine results in increased expression of TLR8 mRNA
CTD
PMID:35283115
NCBI chr X:27,091,780...27,116,092
Ensembl chr X:27,091,778...27,116,549
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Tlr9
toll-like receptor 9
increases expression
EXP
Lidocaine results in increased expression of TLR9 mRNA
CTD
PMID:35283115
NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
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Tmem119
transmembrane protein 119
increases expression
EXP
Lidocaine results in increased expression of TMEM119 mRNA
CTD
PMID:35283115
NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689
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Tmem176b
transmembrane protein 176B
increases expression
EXP
Lidocaine results in increased expression of TMEM176B mRNA
CTD
PMID:35283115
NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384
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Tmprss7
transmembrane serine protease 7
decreases expression
EXP
Lidocaine results in decreased expression of TMPRSS7 mRNA
CTD
PMID:35283115
NCBI chr11:55,127,992...55,166,597
Ensembl chr11:55,128,998...55,164,882
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Tmprss9
transmembrane serine protease 9
increases expression
EXP
Lidocaine results in increased expression of TMPRSS9 mRNA
CTD
PMID:35283115
NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177
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Tnc
tenascin C
increases expression
EXP
Lidocaine results in increased expression of TNC mRNA
CTD
PMID:35283115
NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
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Tnf
tumor necrosis factor
multiple interactions
ISO
Lidocaine inhibits the reaction [TNF protein results in increased cleavage of SELL protein]; Lidocaine inhibits the reaction [TNF protein results in increased expression of [ITGAM protein binds to ITGB2 protein]] Lidocaine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Lidocaine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]
CTD
PMID:9336308 PMID:32471037
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip8l2
TNF alpha induced protein 8 like 2
increases expression
EXP
Lidocaine results in increased expression of TNFAIP8L2 mRNA
CTD
PMID:35283115
NCBI chr 2:182,710,433...182,726,724
Ensembl chr 2:182,709,378...182,726,760
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Tnfrsf12a
TNF receptor superfamily member 12A
increases expression
EXP
Lidocaine results in increased expression of TNFRSF12A mRNA
CTD
PMID:35283115
NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
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Tnni2
troponin I2, fast skeletal type
increases expression
EXP
Lidocaine results in increased expression of TNNI2 mRNA
CTD
PMID:35283115
NCBI chr 1:197,595,012...197,597,554
Ensembl chr 1:197,594,813...197,597,560
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Top6bl
TOP6B like initiator of meiotic double strand breaks
decreases expression
EXP
Lidocaine results in decreased expression of TOP6BL mRNA
CTD
PMID:35283115
NCBI chr 1:201,902,564...201,989,945
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Tp53
tumor protein p53
affects expression decreases expression
ISO EXP
Lidocaine affects the expression of TRP53 mRNA Lidocaine results in decreased expression of TP53 mRNA
CTD
PMID:18931217 PMID:35283115
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpbgl
trophoblast glycoprotein-like
increases expression
EXP
Lidocaine results in increased expression of TPBGL mRNA
CTD
PMID:35283115
NCBI chr 1:153,923,722...153,926,548
Ensembl chr 1:153,925,098...153,926,252
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Tph1
tryptophan hydroxylase 1
increases expression
EXP
Lidocaine results in increased expression of TPH1 mRNA
CTD
PMID:35283115
NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
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Tpx2
TPX2, microtubule nucleation factor
increases expression
EXP
Lidocaine results in increased expression of TPX2 mRNA
CTD
PMID:35283115
NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
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Traip
TRAF-interacting protein
increases expression
EXP
Lidocaine results in increased expression of TRAIP mRNA
CTD
PMID:35283115
NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
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Tram2
translocation associated membrane protein 2
increases expression
EXP
Lidocaine results in increased expression of TRAM2 mRNA
CTD
PMID:35283115
NCBI chr 9:23,419,204...23,498,745
Ensembl chr 9:23,424,232...23,498,689
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Trav12-3
T cell receptor alpha variable 12-3
decreases expression
EXP
Lidocaine results in decreased expression of TRAV12-3 mRNA
CTD
PMID:35283115
NCBI chr15:25,503,871...25,504,883
Ensembl chr15:25,503,985...25,504,565
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Trim7
tripartite motif-containing 7
decreases expression
EXP
Lidocaine results in decreased expression of TRIM7 mRNA
CTD
PMID:35283115
NCBI chr10:33,205,491...33,221,482
Ensembl chr10:33,205,491...33,221,468
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Trip13
thyroid hormone receptor interactor 13
increases expression
EXP
Lidocaine results in increased expression of TRIP13 mRNA
CTD
PMID:35283115
NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
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Troap
trophinin associated protein
increases expression
EXP
Lidocaine results in increased expression of TROAP mRNA
CTD
PMID:35283115
NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365
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Trpa1
transient receptor potential cation channel, subfamily A, member 1
increases activity
ISO EXP
Lidocaine results in increased activity of TRPA1 protein
CTD
PMID:18172555
NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
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Trpv1
transient receptor potential cation channel, subfamily V, member 1
increases activity multiple interactions
ISO EXP
Lidocaine results in increased activity of TRPV1 protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Lidocaine results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Lidocaine results in increased activity of TRPV1 protein]; Lidocaine promotes the reaction [Camphor results in increased activity of TRPV1 protein]; Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Lidocaine promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [Lidocaine results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; oxophenylarsine inhibits the reaction [Lidocaine results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Lidocaine results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lidocaine results in increased activity of TRPV1 protein] TRPV1 protein affects the reaction [Lidocaine results in increased secretion of CALCA protein]
CTD
PMID:18172555
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Ttk
Ttk protein kinase
increases expression
EXP
Lidocaine results in increased expression of TTK mRNA
CTD
PMID:35283115
NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
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Tyms
thymidylate synthetase
increases expression
EXP
Lidocaine results in increased expression of TYMS mRNA
CTD
PMID:35283115
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Tyrobp
transmembrane immune signaling adaptor Tyrobp
increases expression
EXP
Lidocaine results in increased expression of TYROBP mRNA
CTD
PMID:35283115
NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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Ubd
ubiquitin D
decreases expression
EXP
Lidocaine results in decreased expression of UBD mRNA
CTD
PMID:35283115
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Ube2c
ubiquitin-conjugating enzyme E2C
increases expression
EXP
Lidocaine results in increased expression of UBE2C mRNA
CTD
PMID:35283115
NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
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Ube2t
ubiquitin-conjugating enzyme E2T
increases expression
EXP
Lidocaine results in increased expression of UBE2T mRNA
CTD
PMID:35283115
NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835
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Ubl7
ubiquitin-like 7
decreases expression
EXP
Lidocaine results in decreased expression of UBL7 protein
CTD
PMID:27018092
NCBI chr 8:58,321,279...58,340,353
Ensembl chr 8:58,320,866...58,340,344
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Uchl1
ubiquitin C-terminal hydrolase L1
multiple interactions decreases expression
ISO
NGF protein inhibits the reaction [Lidocaine results in decreased expression of UCHL1 protein]; NNAT protein inhibits the reaction [Lidocaine results in decreased expression of UCHL1 protein]
CTD
PMID:34193770
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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Ucn
urocortin
increases expression
EXP
Lidocaine results in increased expression of UCN mRNA
CTD
PMID:35283115
NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
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Ucp2
uncoupling protein 2
increases expression
EXP
Lidocaine results in increased expression of UCP2 mRNA
CTD
PMID:35283115
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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Unc5cl
unc-5 family C-terminal like
increases expression
EXP
Lidocaine results in increased expression of UNC5CL mRNA
CTD
PMID:35283115
NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233
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Unc93b1
unc-93 homolog B1, TLR signaling regulator
increases expression
EXP
Lidocaine results in increased expression of UNC93B1 mRNA
CTD
PMID:35283115
NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338
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Usp18
ubiquitin specific peptidase 18
increases expression
EXP
Lidocaine results in increased expression of USP18 mRNA
CTD
PMID:35283115
NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
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Uts2
urotensin 2
increases expression
EXP
Lidocaine results in increased expression of UTS2 mRNA
CTD
PMID:35283115
NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
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Vav1
vav guanine nucleotide exchange factor 1
increases expression
EXP
Lidocaine results in increased expression of VAV1 mRNA
CTD
PMID:35283115
NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
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Vcan
versican
increases expression
EXP
Lidocaine results in increased expression of VCAN mRNA
CTD
PMID:35283115
NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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Vgf
VGF nerve growth factor inducible
increases expression
EXP
Lidocaine results in increased expression of VGF mRNA
CTD
PMID:35283115
NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
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Vwa5al1
von Willebrand factor A domain containing 5A like 1
decreases expression
EXP
Lidocaine results in decreased expression of VWA5AL1 mRNA
CTD
PMID:35283115
NCBI chr 8:39,869,937...39,890,669
Ensembl chr 8:39,870,563...39,893,187
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Wdfy4
WDFY family member 4
increases expression
EXP
Lidocaine results in increased expression of WDFY4 mRNA
CTD
PMID:35283115
NCBI chr16:8,221,853...8,450,494
Ensembl chr16:8,221,719...8,450,491
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Zbp1
Z-DNA binding protein 1
increases expression
EXP
Lidocaine results in increased expression of ZBP1 mRNA
CTD
PMID:35283115
NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870
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Zc3hav1
zinc finger CCCH-type containing, antiviral 1
increases expression
EXP
Lidocaine results in increased expression of ZC3HAV1 mRNA
CTD
PMID:35283115
NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
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Zfp281
zinc finger protein 281
decreases expression
EXP
Lidocaine results in decreased expression of ZFP281 mRNA
CTD
PMID:35283115
NCBI chr13:48,096,103...48,104,265
Ensembl chr13:48,037,286...48,104,888
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Zfp597
zinc finger protein 597
decreases expression
EXP
Lidocaine results in decreased expression of ZFP597 mRNA
CTD
PMID:35283115
NCBI chr10:11,653,169...11,658,843
Ensembl chr10:11,653,127...11,660,675
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