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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:monolignol
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Accession:CHEBI:64477 term browser browse the term
Definition:A metabolite of plant origin (phytochemical) which acts as a source material for biosynthesis of both lignans and lignin.
Synonyms:related_synonym: monolignols
 xref: Wikipedia:Monolignol



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(+)-pinoresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression
ISO [loliolide co-treated with pinoresinol] results in decreased expression of ACACA protein
pinoresinol results in decreased expression of ACACA protein
CTD PMID:31610126 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression
ISO [loliolide co-treated with pinoresinol] results in decreased expression of FASN protein
pinoresinol results in decreased expression of FASN protein
CTD PMID:31610126 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H2 protein CTD PMID:31610126 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H3 protein CTD PMID:31610126 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pinoresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions
ISO pinoresinol results in decreased expression of SREBF1 protein
[loliolide co-treated with pinoresinol] results in decreased expression of SREBF1 protein
CTD PMID:31610126 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO pinoresinol results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
syringin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO syringin results in increased expression of BAX protein CTD PMID:35580997 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO syringin results in decreased expression of BCL2 protein CTD PMID:35580997 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO syringin results in decreased expression of BIRC5 protein CTD PMID:35580997 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein] CTD PMID:33146439 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO syringin results in increased expression of CCND1 protein CTD PMID:35580997 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdh1 cadherin 1 increases expression ISO syringin results in increased expression of CDH1 protein CTD PMID:35580997 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Ifng interferon gamma multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein] CTD PMID:33146439 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il13 interleukin 13 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:33146439 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:33146439 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:33146439 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein] CTD PMID:33146439 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein] CTD PMID:33146439 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein] CTD PMID:33146439 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases phosphorylation ISO syringin results in increased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein] CTD PMID:33146439 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO syringin results in decreased expression of SQSTM1 protein CTD PMID:35580997 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein] CTD PMID:33146439 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO syringin results in increased expression of TP53 protein CTD PMID:35580997 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            eukaryotic metabolite 19387
              plant metabolite 17985
                monolignol 26
                  coniferol + 7
                  trans-p-coumaryl alcohol + 0
                  trans-sinapyl alcohol + 20
paths to the root