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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:levonorgestrel
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Accession:CHEBI:6443 term browser browse the term
Definition:A terminal acetylenic compound that has formula C21H28O2.
Synonyms:exact_synonym: 17alpha-ethynyl-17beta-hydroxy-18a-homoestr-4-en-3-one
 related_synonym: (-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one;   13-Ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one;   13-Ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one;   13-beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one;   17-Ethynyl-18-methyl-19-nortestosterone;   17-alpha-Ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one;   17-alpha-Ethynyl-13-ethyl-19-nortestosterone;   17alpha-Ethynyl-13beta-ethyl-3-oxo-4-estren-17beta-ol;   17alpha-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one;   17alpha-Ethynyl-18-homo-19-nortestosterone;   18-Methyl-17-alpha-ethynyl-19-nortestosterone;   18-Methylnorethisterone;   Formula=C21H28O2;   InChI=1S/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1;   InChIKey=WWYNJERNGUHSAO-XUDSTZEESA-N;   Jadelle;   Levonelle;   Levonova;   Microlut;   Microluton;   Microval;   Mirena;   NorLevo;   Plan B;   Postinor;   SMILES=[H][C@]12CCC(=O)C=C1CC[C@]1([H])[C@]2([H])CC[C@@]2(CC)[C@@]1([H])CC[C@@]2(O)C#C;   d(-)-Norgestrel;   levonorgestrelum
 xref: Beilstein:6067808;   CAS:6533-00-2;   CAS:797-63-7;   DrugBank:DB00367;   KEGG:C08149;   KEGG:C08153;   KEGG:D00950;   KEGG:D00954;   LIPID_MAPS_instance:LMST02030119
 xref_mesh: MESH:D016912
 xref: PDBeChem:NOG;   Patent:BE623844;   Patent:US3959322
 cyclic_relationship: is_enantiomer_of CHEBI:50900


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levonorgestrel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Levonorgestrel results in increased expression of ABCB1 mRNA CTD PMID:15290871 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ABHD5 mRNA CTD PMID:19074003 NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ACE2 mRNA CTD PMID:19074003 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ADGRF5 mRNA CTD PMID:19074003 NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein] CTD PMID:29782964 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Afg1l AFG1 like ATPase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of AFG1L mRNA CTD PMID:19074003 NCBI chr20:47,038,824...47,208,812 JBrowse link
G Agt angiotensinogen multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of AGT protein CTD PMID:17519148 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahctf1 AT hook containing transcription factor 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of AHCTF1 mRNA CTD PMID:19074003 NCBI chr13:98,023,528...98,079,138
Ensembl chr13:98,023,430...98,078,946
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Levonorgestrel results in decreased activity of AKR1C3 protein CTD PMID:21182831 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ALMS1 mRNA CTD PMID:19074003 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
JBrowse link
G Alpk2 alpha-kinase 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ALPK2 mRNA CTD PMID:19074003 NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein] CTD PMID:12521655 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Ammecr1 AMMECR nuclear protein 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of AMMECR1 mRNA CTD PMID:19074003 NCBI chr  X:114,129,829...114,233,013
Ensembl chr  X:114,131,898...114,232,939
JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ANKDD1A mRNA CTD PMID:19074003 NCBI chr 8:71,034,630...71,057,265
Ensembl chr 8:71,035,309...71,055,969
JBrowse link
G Api5 apoptosis inhibitor 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of API5 mRNA CTD PMID:19074003 NCBI chr 3:83,310,878...83,336,053
Ensembl chr 3:83,310,884...83,335,960
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of APOB protein CTD PMID:15769986 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
Levonorgestrel binds to AR protein
Levonorgestrel binds to and results in increased activity of AR protein
CTD PMID:14565775, PMID:19833195, PMID:20438827 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgap23 Rho GTPase activating protein 23 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ARHGAP23 mRNA CTD PMID:19074003 NCBI chr10:85,387,219...85,445,805
Ensembl chr10:85,384,881...85,444,556
JBrowse link
G Arl9 ADP-ribosylation factor like GTPase 9 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ARL9 mRNA CTD PMID:19074003 NCBI chr14:33,436,803...33,447,516
Ensembl chr14:33,436,980...33,444,235
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ASAP1 mRNA CTD PMID:19074003 NCBI chr 7:104,670,076...104,951,090
Ensembl chr 7:104,669,672...104,801,045
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of AZGP1 mRNA CTD PMID:19074003 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of B4GALT5 mRNA CTD PMID:19074003 NCBI chr 3:164,039,731...164,055,561
Ensembl chr 3:164,039,731...164,095,878
JBrowse link
G Bbx BBX high mobility group box domain containing multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of BBX mRNA CTD PMID:19074003 NCBI chr11:52,983,286...53,228,557
Ensembl chr11:53,081,025...53,228,716
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Levonorgestrel results in decreased expression of BCL2 protein CTD PMID:16019350 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l14 BCL2 like 14 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of BCL2L14 mRNA CTD PMID:19074003 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of BGLAP protein] CTD PMID:12521655 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Btbd3 BTB domain containing 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of BTBD3 mRNA CTD PMID:19074003 NCBI chr 3:131,330,338...131,360,554
Ensembl chr 3:131,351,587...131,357,929
JBrowse link
G C3 complement C3 multiple interactions EXP Levonorgestrel inhibits the reaction [Ethinyl Estradiol results in increased expression of C3 mRNA] CTD PMID:11566438 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4bpb complement component 4 binding protein, beta multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein; F5 gene polymorphism inhibits the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein] CTD PMID:14551147 NCBI chr13:47,387,173...47,398,115
Ensembl chr13:47,387,173...47,397,890
JBrowse link
G Cat catalase multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of CAT protein CTD PMID:17541152 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccn3 cellular communication network factor 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CCN3 mRNA CTD PMID:19074003 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CD86 mRNA CTD PMID:19074003 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CDC25C mRNA CTD PMID:19074003 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc42bpb CDC42 binding protein kinase beta multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CDC42BPB mRNA CTD PMID:19074003 NCBI chr 6:135,746,743...135,830,144
Ensembl chr 6:135,746,754...135,830,086
JBrowse link
G Cep170b centrosomal protein 170B multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CEP170B mRNA CTD PMID:19074003 NCBI chr 6:137,283,814...137,311,512
Ensembl chr 6:137,288,810...137,311,932
JBrowse link
G Cfap65 cilia and flagella associated protein 65 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CFAP65 mRNA CTD PMID:19074003 NCBI chr 9:82,163,016...82,197,909
Ensembl chr 9:82,163,075...82,195,722
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CHEK2 mRNA CTD PMID:19074003 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of COL1A1 mRNA CTD PMID:19074003 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col22a1 collagen type XXII alpha 1 chain multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of COL22A1 mRNA CTD PMID:19074003 NCBI chr 7:113,014,896...113,251,165
Ensembl chr 7:113,015,747...113,228,439
JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CPEB3 mRNA CTD PMID:19074003 NCBI chr 1:255,660,165...255,842,671
Ensembl chr 1:255,665,238...255,815,733
JBrowse link
G Cpxcr1 CPX chromosome region, candidate 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CPXCR1 mRNA CTD PMID:19074003 NCBI chr  X:49,243,273...49,244,985 JBrowse link
G Crlf3 cytokine receptor-like factor 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CRLF3 mRNA CTD PMID:19074003 NCBI chr10:67,383,664...67,401,836
Ensembl chr10:67,383,900...67,401,836
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of CRP protein CTD PMID:15769986 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CSMD1 mRNA CTD PMID:19074003 NCBI chr16:77,152,823...78,850,222
Ensembl chr16:78,539,489...78,850,222
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CSNK1A1 mRNA CTD PMID:19074003 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of CXCL10 mRNA CTD PMID:19074003 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CYP17A1 mRNA CTD PMID:19074003 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Dap3 death associated protein 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DAP3 mRNA CTD PMID:19074003 NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725
JBrowse link
G Dcn decorin multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DCN mRNA CTD PMID:19074003 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddhd1 DDHD domain containing 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DDHD1 mRNA CTD PMID:19074003 NCBI chr15:19,963,639...20,032,263
Ensembl chr15:19,965,187...20,032,191
JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DLGAP2 mRNA CTD PMID:19074003 NCBI chr16:79,872,238...80,596,977
Ensembl chr16:79,872,323...79,973,877
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DNASE1L3 mRNA CTD PMID:19074003 NCBI chr15:18,710,492...18,736,476
Ensembl chr15:18,710,492...18,736,473
JBrowse link
G Dock8 dedicator of cytokinesis 8 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of DOCK8 mRNA CTD PMID:19074003 NCBI chr 1:242,934,685...243,153,472
Ensembl chr 1:242,959,488...243,153,465
JBrowse link
G Dok5 docking protein 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DOK5 mRNA CTD PMID:19074003 NCBI chr 3:168,345,116...168,482,445
Ensembl chr 3:168,345,152...168,482,441
JBrowse link
G Dsg1 desmoglein 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of DSG1 mRNA CTD PMID:19074003 NCBI chr18:12,008,301...12,040,337
Ensembl chr18:12,008,759...12,038,053
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ELOVL5 mRNA CTD PMID:19074003 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of EPRS1 mRNA CTD PMID:19074003 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Esr1 estrogen receptor 1 increases activity EXP Norgestrel results in increased activity of ESR1 protein CTD PMID:11750080, PMID:12504345 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etnk1 ethanolamine kinase 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ETNK1 mRNA CTD PMID:19074003 NCBI chr 4:177,402,904...177,447,047
Ensembl chr 4:177,402,904...177,447,028
JBrowse link
G Evi2b ecotropic viral integration site 2B multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of EVI2B mRNA CTD PMID:19074003 NCBI chr10:66,856,980...66,858,598
Ensembl chr10:66,856,980...66,858,598
JBrowse link
G F5 coagulation factor V multiple interactions ISO F5 gene polymorphism inhibits the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein] CTD PMID:14551147 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G F7 coagulation factor VII multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of F7 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of F7 protein CTD PMID:12618251, PMID:15157790 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G F8 coagulation factor VIII multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of F8 protein CTD PMID:12618251 NCBI chr18:367,862...399,242
Ensembl chr18:367,862...399,242
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Norgestrel co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FAM20A mRNA CTD PMID:19074003 NCBI chr10:97,962,467...98,017,171
Ensembl chr10:97,962,693...98,018,014
JBrowse link
G Far2 fatty acyl CoA reductase 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FAR2 mRNA CTD PMID:19074003 NCBI chr 4:182,446,400...182,563,485
Ensembl chr 4:182,483,194...182,565,436
JBrowse link
G Fcrl5 Fc receptor-like 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FCRL5 mRNA CTD PMID:19074003 NCBI chr 2:186,776,466...186,797,900
Ensembl chr 2:186,776,605...186,808,078
JBrowse link
G Fermt2 fermitin family member 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FERMT2 mRNA CTD PMID:19074003 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein] CTD PMID:12618251, PMID:15288212 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein] CTD PMID:12618251, PMID:15288212 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of [FGA protein binds to FGB protein binds to FGG protein] CTD PMID:12618251, PMID:15288212 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fkbp6 FKBP prolyl isomerase 6 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of FKBP6 mRNA CTD PMID:19074003 NCBI chr12:24,365,941...24,438,088
Ensembl chr12:24,367,199...24,438,019
JBrowse link
G Fmnl3 formin-like 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of FMNL3 mRNA CTD PMID:19074003 NCBI chr 7:140,981,801...141,033,318
Ensembl chr 7:140,983,342...141,001,993
JBrowse link
G Fnbp1 formin binding protein 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of FNBP1 mRNA CTD PMID:19074003 NCBI chr 3:9,865,657...9,936,333
Ensembl chr 3:9,861,237...9,936,405
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of FSHB protein; Avosentan affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of FSHB protein] CTD PMID:16291413, PMID:17190377 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 increases expression EXP Levonorgestrel results in increased expression of GABRG2 protein CTD PMID:22634062 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of GAS6 protein CTD PMID:17717130 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gdf10 growth differentiation factor 10 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of GDF10 mRNA CTD PMID:19074003 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of GH1 protein CTD PMID:11172797 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Glyr1 glyoxylate reductase 1 homolog multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of GLYR1 mRNA CTD PMID:19074003 NCBI chr10:10,725,830...10,759,471
Ensembl chr10:10,725,819...10,761,279
JBrowse link
G Gpr135 G protein-coupled receptor 135 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of GPR135 mRNA CTD PMID:19074003 NCBI chr 6:94,816,976...94,818,349
Ensembl chr 6:94,816,976...94,818,349
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of GREB1 mRNA CTD PMID:19074003 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Hmmr hyaluronan-mediated motility receptor multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HMMR mRNA CTD PMID:19074003 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hoxc6 homeo box C6 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HOXC6 mRNA CTD PMID:19074003 NCBI chr 7:144,612,230...144,626,036
Ensembl chr 7:144,623,555...144,625,516
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HTR7 mRNA CTD PMID:19074003 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ICE2 mRNA CTD PMID:19074003 NCBI chr 8:75,625,147...75,666,959
Ensembl chr 8:75,625,174...75,666,866
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of IGF1 protein CTD PMID:11172797 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of IGFBP3 mRNA CTD PMID:19074003 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igsf1 immunoglobulin superfamily, member 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of IGSF1 mRNA CTD PMID:19074003 NCBI chr  X:136,792,637...136,808,107
Ensembl chr  X:136,792,643...136,807,885
JBrowse link
G Inha inhibin subunit alpha multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of INHA mRNA CTD PMID:19074003 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Norgestrel co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein; Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Norgestrel inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein] CTD PMID:29782964 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insl3 insulin-like 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of INSL3 mRNA CTD PMID:19074003 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Insl6 insulin-like 6 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of INSL6 mRNA CTD PMID:19074003 NCBI chr 1:247,473,292...247,476,827
Ensembl chr 1:247,473,292...247,476,827
JBrowse link
G Kbtbd7 kelch repeat and BTB domain containing 7 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KBTBD7 mRNA CTD PMID:19074003 NCBI chr15:61,692,041...61,696,506 JBrowse link
G Kcnh7 potassium voltage-gated channel subfamily H member 7 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of KCNH7 mRNA CTD PMID:19074003 NCBI chr 3:48,662,450...49,168,716
Ensembl chr 3:48,671,079...48,831,467
JBrowse link
G Kdsr 3-ketodihydrosphingosine reductase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KDSR mRNA CTD PMID:19074003 NCBI chr13:26,779,386...26,812,271
Ensembl chr13:26,780,633...26,812,215
JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KLHL28 mRNA CTD PMID:19074003 NCBI chr 6:86,680,826...86,713,370
Ensembl chr 6:86,684,413...86,713,370
JBrowse link
G Klhl4 kelch-like family member 4 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of KLHL4 mRNA CTD PMID:19074003 NCBI chr  X:86,125,929...86,229,565
Ensembl chr  X:86,126,157...86,229,563
JBrowse link
G Ldlr low density lipoprotein receptor affects expression
multiple interactions
ISO Levonorgestrel affects the expression of LDLR protein
[Levonorgestrel co-treated with Ethinyl Estradiol] results in decreased expression of LDLR protein
CTD PMID:17900441 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases secretion
ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of LHB protein; Avosentan affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of LHB protein]
Levonorgestrel results in decreased secretion of LHB protein
CTD PMID:16291413, PMID:17190377, PMID:20599585 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Limd1 LIM domains containing 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of LIMD1 mRNA CTD PMID:19074003 NCBI chr 8:132,553,218...132,598,826
Ensembl chr 8:132,553,218...132,598,812
JBrowse link
G Lmntd1 lamin tail domain containing 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of LMNTD1 mRNA CTD PMID:19074003 NCBI chr 4:179,658,348...179,905,049
Ensembl chr 4:179,651,164...179,904,844
JBrowse link
G LOC681470 similar to olfactory receptor 1403 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of OR10J1 mRNA CTD PMID:19074003 NCBI chr13:91,768,256...91,769,188
Ensembl chr13:91,768,256...91,769,188
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of LRIG2 mRNA CTD PMID:19074003 NCBI chr 2:206,928,708...206,997,915
Ensembl chr 2:206,931,204...206,997,519
JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MAN2A1 mRNA CTD PMID:19074003 NCBI chr 9:112,293,388...112,451,677
Ensembl chr 9:112,293,388...112,451,677
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MBNL1 mRNA CTD PMID:19074003 NCBI chr 2:150,698,248...150,867,791
Ensembl chr 2:150,756,185...150,869,690
JBrowse link
G Mep1b meprin A subunit beta multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of MEP1B mRNA CTD PMID:19074003 NCBI chr18:15,063,159...15,090,877
Ensembl chr18:15,063,079...15,089,988
JBrowse link
G Midn midnolin multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MIDN mRNA CTD PMID:19074003 NCBI chr 7:12,414,303...12,426,712
Ensembl chr 7:12,414,733...12,424,367
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Levonorgestrel results in decreased expression of MKI67 protein CTD PMID:16019350 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mro maestro multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MRO mRNA CTD PMID:19074003 NCBI chr18:69,833,770...69,850,164 JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MRPS6 mRNA CTD PMID:19074003 NCBI chr11:32,208,246...32,263,999
Ensembl chr11:32,211,115...32,263,899
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of MTSS1 mRNA CTD PMID:19074003 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Mysm1 myb-like, SWIRM and MPN domains 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of MYSM1 mRNA CTD PMID:19074003 NCBI chr 5:113,902,115...113,939,083
Ensembl chr 5:113,906,803...113,939,127
JBrowse link
G Nacc2 NACC family member 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NACC2 mRNA CTD PMID:19074003 NCBI chr 3:3,508,084...3,574,787
Ensembl chr 3:3,510,041...3,574,787
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NDFIP1 mRNA CTD PMID:19074003 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
G Nexn nexilin (F actin binding protein) multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NEXN mRNA CTD PMID:19074003 NCBI chr 2:257,452,937...257,484,607
Ensembl chr 2:257,453,347...257,484,587
JBrowse link
G Nid1 nidogen 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NID1 mRNA CTD PMID:19074003 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nsg1 neuronal vesicle trafficking associated 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of NSG1 mRNA CTD PMID:19074003 NCBI chr14:77,380,264...77,402,007
Ensembl chr14:77,380,262...77,401,996
JBrowse link
G Odf3 outer dense fiber of sperm tails 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ODF3 mRNA CTD PMID:19074003 NCBI chr 1:213,596,784...213,602,417
Ensembl chr 1:213,597,478...213,600,685
JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of OLFML3 mRNA CTD PMID:19074003 NCBI chr 2:206,219,419...206,222,248
Ensembl chr 2:206,219,419...206,222,248
JBrowse link
G Opn5 opsin 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of OPN5 mRNA CTD PMID:19074003 NCBI chr 9:21,045,457...21,092,517
Ensembl chr 9:21,045,457...21,093,172
JBrowse link
G Osbpl10 oxysterol binding protein-like 10 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of OSBPL10 mRNA CTD PMID:19074003 NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562
JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PAK3 mRNA CTD PMID:19074003 NCBI chr  X:114,784,452...115,042,683
Ensembl chr  X:114,929,029...115,036,669
JBrowse link
G Pappa1 pappalysin 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PAPPA mRNA CTD PMID:19074003 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Pard6b par-6 family cell polarity regulator beta multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PARD6B mRNA CTD PMID:19074003 NCBI chr 3:164,822,111...164,843,395
Ensembl chr 3:164,822,111...164,843,395
JBrowse link
G Pcdh7 protocadherin 7 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PCDH7 mRNA CTD PMID:19074003 NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551
JBrowse link
G Pde1c phosphodiesterase 1C multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of PDE1C mRNA CTD PMID:19074003 NCBI chr 4:86,359,762...86,925,044
Ensembl chr 4:86,359,820...86,630,543
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Levonorgestrel binds to and results in increased activity of PGR protein CTD PMID:20599585 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pkp4 plakophilin 4 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PKP4 mRNA CTD PMID:19074003 NCBI chr 3:45,211,097...45,414,524
Ensembl chr 3:45,277,348...45,414,613
JBrowse link
G Plagl1 PLAG1 like zinc finger 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PLAGL1 mRNA CTD PMID:19074003 NCBI chr 1:7,219,587...7,270,169
Ensembl chr 1:7,252,349...7,259,035
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of PLAT protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased activity of PLAT protein CTD PMID:12618251, PMID:15157790, PMID:15288212 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plg plasminogen multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of PLG protein CTD PMID:12618251, PMID:15157790 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Poglut1 protein O-glucosyltransferase 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of POGLUT1 mRNA CTD PMID:19074003 NCBI chr11:64,761,493...64,788,210
Ensembl chr11:64,761,146...64,788,208
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] affects the activity of PON1 protein CTD PMID:17541152 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of PPP2R2C mRNA CTD PMID:19074003 NCBI chr14:78,679,214...78,763,175
Ensembl chr14:78,679,214...78,902,063
JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of PRKAB1 mRNA CTD PMID:19074003 NCBI chr12:46,316,298...46,326,789
Ensembl chr12:46,316,236...46,326,790
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased activity of PROC protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of PROC protein CTD PMID:12618251, PMID:14551147, PMID:15288212 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Pros1 protein S multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of PROS1 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of PROS1 protein CTD PMID:12618251, PMID:14551147 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Ptbp2 polypyrimidine tract binding protein 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTBP2 mRNA CTD PMID:19074003 NCBI chr 2:223,261,444...223,323,075
Ensembl chr 2:223,262,852...223,322,585
JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTGER2 mRNA CTD PMID:19074003 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTGES mRNA CTD PMID:19074003 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of RAB11FIP3 mRNA CTD PMID:19074003 NCBI chr10:15,348,356...15,433,384
Ensembl chr10:15,349,888...15,381,691
JBrowse link
G Rab1a RAB1A, member RAS oncogene family multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RAB1A mRNA CTD PMID:19074003 NCBI chr14:104,475,082...104,500,176
Ensembl chr14:104,475,082...104,501,020
JBrowse link
G Rapgef6 Rap guanine nucleotide exchange factor 6 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of RAPGEF6 mRNA CTD PMID:19074003 NCBI chr10:39,875,322...40,039,929
Ensembl chr10:39,875,371...40,039,929
JBrowse link
G Recql RecQ like helicase multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of RECQL mRNA CTD PMID:19074003 NCBI chr 4:176,581,892...176,606,520
Ensembl chr 4:176,581,897...176,606,382
JBrowse link
G Rftn2 raftlin family member 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RFTN2 mRNA CTD PMID:19074003 NCBI chr 9:61,754,859...61,810,992
Ensembl chr 9:61,756,428...61,810,417
JBrowse link
G Rln1 relaxin 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RLN1 mRNA CTD PMID:19074003 NCBI chr 1:247,483,298...247,486,331
Ensembl chr 1:247,483,302...247,486,202
JBrowse link
G Rnf216 ring finger protein 216 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RNF216 mRNA CTD PMID:19074003 NCBI chr12:13,508,429...13,631,689
Ensembl chr12:13,508,429...13,632,304
JBrowse link
G Rnft1 ring finger protein, transmembrane 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of RNFT1 mRNA CTD PMID:19074003 NCBI chr10:73,807,455...73,821,178
Ensembl chr10:73,809,157...73,817,982
JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of HLA-DQB1 mRNA CTD PMID:19074003 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G Saraf store-operated calcium entry-associated regulatory factor multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SARAF mRNA CTD PMID:19074003 NCBI chr16:61,735,189...61,753,438
Ensembl chr16:61,735,181...61,753,476
JBrowse link
G Scaf4 SR-related CTD-associated factor 4 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SCAF4 mRNA CTD PMID:19074003 NCBI chr11:30,371,713...30,428,073
Ensembl chr11:30,371,713...30,428,073
JBrowse link
G Senp1 SUMO specific peptidase 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SENP1 mRNA CTD PMID:19074003 NCBI chr 7:139,626,444...139,684,587
Ensembl chr 7:139,630,515...139,675,245
JBrowse link
G Serpina5 serpin family A member 5 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of SERPINA5 protein CTD PMID:14551147 NCBI chr 6:127,753,152...127,772,403
Ensembl chr 6:127,766,470...127,772,420
JBrowse link
G Serpinb3 serpin family B member 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SERPINB3 mRNA CTD PMID:19074003 NCBI chr13:27,186,701...27,193,211
Ensembl chr13:27,187,130...27,192,592
JBrowse link
G Serpinc1 serpin family C member 1 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINC1 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINC1 protein CTD PMID:12618251, PMID:14981370, PMID:15288212 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINE1 protein; [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINE1 protein CTD PMID:14981370, PMID:15157790, PMID:15288212 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sfrp5 secreted frizzled-related protein 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SFRP5 mRNA CTD PMID:19074003 NCBI chr 1:261,442,108...261,446,570
Ensembl chr 1:261,442,108...261,446,570
JBrowse link
G Shbg sex hormone binding globulin affects binding
multiple interactions
ISO Levonorgestrel binds to SHBG protein
[Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of SHBG protein
CTD PMID:12586319, PMID:14981370, PMID:17519148 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Slc16a9 solute carrier family 16, member 9 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SLC16A9 mRNA CTD PMID:19074003 NCBI chr20:19,634,280...19,675,358 JBrowse link
G Slc25a2 solute carrier family 25 member 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SLC25A2 mRNA CTD PMID:19074003 NCBI chr18:30,774,205...30,775,401
Ensembl chr18:30,774,205...30,775,401
JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SLC2A5 mRNA CTD PMID:19074003 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Smyd2 SET and MYND domain containing 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SMYD2 mRNA CTD PMID:19074003 NCBI chr13:108,642,156...108,686,293
Ensembl chr13:108,642,156...108,686,290
JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SNRPN mRNA CTD PMID:19074003 NCBI chr 1:195,074,328...195,096,460
Ensembl chr 1:195,074,330...195,096,460
JBrowse link
G Sobp sine oculis binding protein homolog multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of SOBP mRNA CTD PMID:19074003 NCBI chr20:47,731,713...47,910,466
Ensembl chr20:47,750,762...47,910,375
JBrowse link
G Spin4 spindlin family, member 4 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SPIN4 mRNA CTD PMID:19074003 NCBI chr  X:64,217,074...64,221,225 JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SPTBN1 mRNA CTD PMID:19074003 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Srgn serglycin multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SRGN mRNA CTD PMID:19074003 NCBI chr20:32,120,317...32,158,071
Ensembl chr20:32,120,320...32,139,789
JBrowse link
G Stxbp5l syntaxin binding protein 5-like multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of STXBP5L mRNA CTD PMID:19074003 NCBI chr11:66,246,624...66,566,331
Ensembl chr11:66,316,606...66,566,331
JBrowse link
G Syt11 synaptotagmin 11 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of SYT11 mRNA CTD PMID:19074003 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Tmem217 transmembrane protein 217 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of TMEM217 mRNA CTD PMID:19074003 NCBI chr20:8,202,165...8,202,956
Ensembl chr20:8,202,355...8,202,924
JBrowse link
G Tmem225 transmembrane protein 225 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of TMEM225 mRNA CTD PMID:19074003 NCBI chr 8:44,001,199...44,003,757
Ensembl chr 8:44,001,096...44,004,044
JBrowse link
G Tmem35a transmembrane protein 35A multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TMEM35A mRNA CTD PMID:19074003 NCBI chr  X:105,134,498...105,145,346
Ensembl chr  X:105,134,498...105,145,345
JBrowse link
G Tmod2 tropomodulin 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TMOD2 mRNA CTD PMID:19074003 NCBI chr 8:82,505,947...82,547,450
Ensembl chr 8:82,506,934...82,533,689
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of TNF protein CTD PMID:15769986 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO Levonorgestrel results in increased expression of TNFRSF11B mRNA CTD PMID:16114553 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Levonorgestrel results in decreased expression of TNFSF11 mRNA CTD PMID:16114553 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnrc6b trinucleotide repeat containing adaptor 6B multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TNRC6B mRNA CTD PMID:19074003 NCBI chr 7:121,930,610...122,147,934
Ensembl chr 7:121,930,615...122,147,934
JBrowse link
G Tra2a transformer 2 alpha homolog multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TRA2A mRNA CTD PMID:19074003 NCBI chr 4:78,905,380...78,924,203
Ensembl chr 4:78,905,380...78,924,181
JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TRMT13 mRNA CTD PMID:19074003 NCBI chr 2:219,615,665...219,628,824
Ensembl chr 2:219,615,420...219,628,997
JBrowse link
G Ttc37 tetratricopeptide repeat domain 37 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of TTC37 mRNA CTD PMID:19074003 NCBI chr 2:2,891,265...3,037,602
Ensembl chr 2:2,903,492...3,004,553
JBrowse link
G Ubap1 ubiquitin-associated protein 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of UBAP1 mRNA CTD PMID:19074003 NCBI chr 5:57,738,309...57,778,724
Ensembl chr 5:57,738,321...57,778,723
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of UBE2D3 mRNA CTD PMID:19074003 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of VCAM1 protein CTD PMID:15769986 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein]; VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of BGLAP protein] CTD PMID:12521655 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Levonorgestrel results in increased expression of VEGFA mRNA; Levonorgestrel results in increased expression of VEGFA mRNA alternative form CTD PMID:17010073 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Xylt1 xylosyltransferase 1 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of XYLT1 mRNA CTD PMID:19074003 NCBI chr 1:186,939,698...187,264,758
Ensembl chr 1:187,149,453...187,261,632
JBrowse link
G Yeats2 YEATS domain containing 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of YEATS2 mRNA CTD PMID:19074003 NCBI chr11:84,330,064...84,595,296
Ensembl chr11:84,330,064...84,583,542
JBrowse link
G Zcchc7 zinc finger CCHC-type containing 7 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZCCHC7 mRNA CTD PMID:19074003 NCBI chr 5:60,250,546...60,430,119
Ensembl chr 5:60,250,546...60,429,708
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZEB2 mRNA CTD PMID:19074003 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
G Zfand6 zinc finger AN1-type containing 6 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZFAND6 mRNA CTD PMID:19074003 NCBI chr 1:146,745,850...146,823,762
Ensembl chr 1:146,745,859...146,823,762
JBrowse link
G Zfp518a zinc finger protein 518A multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZNF518A mRNA CTD PMID:19074003 NCBI chr 1:260,152,881...260,178,360
Ensembl chr 1:260,153,645...260,178,349
JBrowse link
G Zfp638 zinc finger protein 638 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZNF638 mRNA CTD PMID:19074003 NCBI chr 4:115,555,185...115,690,272
Ensembl chr 4:115,601,661...115,690,272
JBrowse link
G Zfr zinc finger RNA binding protein multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of ZFR mRNA CTD PMID:19074003 NCBI chr 2:62,150,251...62,213,048
Ensembl chr 2:62,150,251...62,213,048
JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 multiple interactions ISO [testosterone undecanoate co-treated with Levonorgestrel] results in increased expression of ZKSCAN7 mRNA CTD PMID:19074003 NCBI chr 8:131,932,753...131,968,550
Ensembl chr 8:131,933,387...131,950,776
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19801
    chemical entity 19800
      group 19707
        organic group 18520
          3-oxo-Delta(4)-steroid group 7939
            3-oxo-Delta(4) steroid 7939
              levonorgestrel 195
Path 2
Term Annotations click to browse term
  CHEBI ontology 19801
    subatomic particle 19797
      composite particle 19797
        hadron 19797
          baryon 19797
            nucleon 19797
              atomic nucleus 19797
                atom 19797
                  main group element atom 19684
                    p-block element atom 19684
                      carbon group element atom 19583
                        carbon atom 19572
                          organic molecular entity 19572
                            organic group 18520
                              organic divalent group 18513
                                organodiyl group 18513
                                  carbonyl group 18415
                                    carbonyl compound 18415
                                      ketone 16154
                                        oxo steroid 9285
                                          3-oxo steroid 8812
                                            3-oxo-Delta(4) steroid 7939
                                              norgestrel 195
                                                levonorgestrel 195
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.