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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:meroterpenoid
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Accession:CHEBI:64419 term browser browse the term
Definition:Meroterpenoids are complex organooxygen natural products produced from polyketide and terpenoid precursors.
Synonyms:related_synonym: meroterpenoids


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andrastin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 multiple interactions ISO andrastin A results in increased expression of and results in increased secretion of CSF2 protein CTD PMID:28535995 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO andrastin A results in increased expression of and results in increased secretion of TGFB1 protein CTD PMID:28535995 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO andrastin A results in increased expression of and results in increased secretion of TNF protein CTD PMID:28535995 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
fumagillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA] CTD PMID:15682466 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Metap1 methionyl aminopeptidase 1 decreases activity
multiple interactions
ISO fumagillin results in decreased activity of METAP1 protein
[fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein
CTD PMID:14534293 NCBI chr 2:243,744,620...243,777,673
Ensembl chr 2:243,744,620...243,777,673
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions
decreases activity
EXP
ISO
fumagillin promotes the reaction [Diethylnitrosamine results in increased expression of METAP2 mRNA]
fumagillin results in decreased activity of METAP2 protein
[fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein
CTD PMID:14534293, PMID:15516829, PMID:15682466 NCBI chr 7:34,762,241...34,789,456
Ensembl chr 7:34,762,231...34,789,479
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions EXP fumagillin inhibits the reaction [Diethylnitrosamine results in increased activity of TERT protein]; fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of TERT mRNA] CTD PMID:15682466 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma multiple interactions ISO [fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein CTD PMID:14534293 NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            meroterpenoid 8
              (+)-makassaric acid 0
              (+)-subersic acid 0
              (2E,6Z)-13-hydroxy-1-(2-hydroxy-5-methoxy-3-methylphenyl)-3,7,11,15-tetramethylhexadeca-2,6,14-triene-5,12-dione 0
              (4R)-ipsdienol 0
              11,20-dihydroxyferruginol + 0
              11,20-dihydroxysugiol 0
              11-hydroxyferruginol 0
              11-hydroxysugiol + 0
              6beta-hydroxyferruginol 0
              andrastin A 3
              andrastin B + 3
              andrastin C + 3
              andrastin D + 0
              andrastin E 0
              andrastin F 0
              ascochlorin 0
              ascofuranol 0
              ascofuranone 0
              asnovolin A 0
              asnovolin H 0
              austinol 0
              berkeleydione 0
              berkeleyone A 0
              berkeleyone B 0
              berkeleyone C 0
              berkeleytrione 0
              chermesin D 0
              deacetylpyripyropene E 0
              dehydroaustinol 0
              ferruginol + 0
              fumagillin + 5
              fumicycline A 0
              guignardone N 0
              liphagal 0
              novofumigatonin 0
              paraherquonin 0
              preaustinoid A 0
              preaustinoid A1 0
              preaustinoid A2 0
              preaustinoid A3 0
              protoaustinoid A 0
              protoaustinoid B 0
              salviol 0
              strongylophorine-26 0
              sugiol + 0
              terretonin 0
              yanuthones + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            organic hydride 18249
                              organic fundamental parent 18249
                                hydrocarbon 17969
                                  terpene 9594
                                    terpenoid 9578
                                      meroterpenoid 8
                                        (+)-makassaric acid 0
                                        (+)-subersic acid 0
                                        (2E,6Z)-13-hydroxy-1-(2-hydroxy-5-methoxy-3-methylphenyl)-3,7,11,15-tetramethylhexadeca-2,6,14-triene-5,12-dione 0
                                        (4R)-ipsdienol 0
                                        11,20-dihydroxyferruginol + 0
                                        11,20-dihydroxysugiol 0
                                        11-hydroxyferruginol 0
                                        11-hydroxysugiol + 0
                                        6beta-hydroxyferruginol 0
                                        andrastin A 3
                                        andrastin B + 3
                                        andrastin C + 3
                                        andrastin D + 0
                                        andrastin E 0
                                        andrastin F 0
                                        ascochlorin 0
                                        ascofuranol 0
                                        ascofuranone 0
                                        asnovolin A 0
                                        asnovolin H 0
                                        austinol 0
                                        berkeleydione 0
                                        berkeleyone A 0
                                        berkeleyone B 0
                                        berkeleyone C 0
                                        berkeleytrione 0
                                        chermesin D 0
                                        deacetylpyripyropene E 0
                                        dehydroaustinol 0
                                        ferruginol + 0
                                        fumagillin + 5
                                        fumicycline A 0
                                        guignardone N 0
                                        liphagal 0
                                        novofumigatonin 0
                                        paraherquonin 0
                                        preaustinoid A 0
                                        preaustinoid A1 0
                                        preaustinoid A2 0
                                        preaustinoid A3 0
                                        protoaustinoid A 0
                                        protoaustinoid B 0
                                        salviol 0
                                        strongylophorine-26 0
                                        sugiol + 0
                                        terretonin 0
                                        yanuthones + 0
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