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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:meroterpenoid
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Accession:CHEBI:64419 term browser browse the term
Definition:Meroterpenoids are complex organooxygen natural products produced from polyketide and terpenoid precursors.
Synonyms:related_synonym: meroterpenoids


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andrastin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf2 colony stimulating factor 2 multiple interactions ISO andrastin A results in increased expression of and results in increased secretion of CSF2 protein CTD PMID:28535995 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO andrastin A results in increased expression of and results in increased secretion of TGFB1 protein CTD PMID:28535995 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO andrastin A results in increased expression of and results in increased secretion of TNF protein CTD PMID:28535995 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
ferruginol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP ferruginol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein] CTD PMID:32946155 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Il6 interleukin 6 multiple interactions EXP ferruginol inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein] CTD PMID:32946155 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP ferruginol inhibits the reaction [Isoproterenol results in increased secretion of TNF protein] CTD PMID:32946155 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions EXP ferruginol inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein] CTD PMID:32946155 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP ferruginol inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:32946155 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
fumagillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA] CTD PMID:15682466 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Metap1 methionyl aminopeptidase 1 decreases activity
multiple interactions
ISO fumagillin results in decreased activity of METAP1 protein
[fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein
CTD PMID:14534293 NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions
decreases activity
EXP
ISO
fumagillin promotes the reaction [Diethylnitrosamine results in increased expression of METAP2 mRNA]
fumagillin results in decreased activity of METAP2 protein
[fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein
CTD PMID:14534293 PMID:15516829 PMID:15682466 NCBI chr 7:28,412,771...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions EXP fumagillin inhibits the reaction [Diethylnitrosamine results in increased activity of TERT protein]; fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of TERT mRNA] CTD PMID:15682466 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma multiple interactions ISO [fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein CTD PMID:14534293 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            meroterpenoid 12
              (+)-makassaric acid 0
              (+)-subersic acid 0
              (2E,6Z)-13-hydroxy-1-(2-hydroxy-5-methoxy-3-methylphenyl)-3,7,11,15-tetramethylhexadeca-2,6,14-triene-5,12-dione 0
              (4R)-ipsdienol 0
              11,20-dihydroxyferruginol + 0
              11,20-dihydroxysugiol 0
              11-hydroxyferruginol 0
              11-hydroxysugiol + 0
              6beta-hydroxyferruginol 0
              andrastin A 3
              andrastin B + 3
              andrastin C + 3
              andrastin D + 0
              andrastin E 0
              andrastin F 0
              ascochlorin 0
              ascofuranol 0
              ascofuranone 0
              asnovolin A 0
              asnovolin H(1-) 0
              asnovolin I 0
              asnovolin J 0
              asnovolin K 0
              austinol 0
              berkeleydione 0
              berkeleyone A 0
              berkeleyone B 0
              berkeleyone C 0
              berkeleytrione 0
              biscognienyne B 0
              chermesin D methyl ester 0
              chermesin D(1-) 0
              deacetylpyripyropene E 0
              dehydroaustinol 0
              ferruginol + 5
              fumagillin + 5
              fumicycline A 0
              fumigatonoid A 0
              fumigatonoid B 0
              fumigatonoid C 0
              guignardone N 0
              liphagal 0
              novofumigatonin 0
              paraherquonin 0
              preaustinoid A 0
              preaustinoid A1 0
              preaustinoid A2 0
              preaustinoid A3 0
              protoaustinoid A 0
              protoaustinoid B 0
              salviol 0
              strongylophorine-26 0
              sugiol + 0
              terretonin 0
              yanuthones + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    main group molecular entity 19716
                      s-block molecular entity 19502
                        hydrogen molecular entity 19498
                          hydrides 18852
                            organic hydride 18353
                              organic fundamental parent 18353
                                hydrocarbon 18066
                                  terpene 12711
                                    terpenoid 12280
                                      meroterpenoid 12
                                        (+)-makassaric acid 0
                                        (+)-subersic acid 0
                                        (2E,6Z)-13-hydroxy-1-(2-hydroxy-5-methoxy-3-methylphenyl)-3,7,11,15-tetramethylhexadeca-2,6,14-triene-5,12-dione 0
                                        (4R)-ipsdienol 0
                                        11,20-dihydroxyferruginol + 0
                                        11,20-dihydroxysugiol 0
                                        11-hydroxyferruginol 0
                                        11-hydroxysugiol + 0
                                        6beta-hydroxyferruginol 0
                                        andrastin A 3
                                        andrastin B + 3
                                        andrastin C + 3
                                        andrastin D + 0
                                        andrastin E 0
                                        andrastin F 0
                                        ascochlorin 0
                                        ascofuranol 0
                                        ascofuranone 0
                                        asnovolin A 0
                                        asnovolin H(1-) 0
                                        asnovolin I 0
                                        asnovolin J 0
                                        asnovolin K 0
                                        austinol 0
                                        berkeleydione 0
                                        berkeleyone A 0
                                        berkeleyone B 0
                                        berkeleyone C 0
                                        berkeleytrione 0
                                        biscognienyne B 0
                                        chermesin D methyl ester 0
                                        chermesin D(1-) 0
                                        deacetylpyripyropene E 0
                                        dehydroaustinol 0
                                        ferruginol + 5
                                        fumagillin + 5
                                        fumicycline A 0
                                        fumigatonoid A 0
                                        fumigatonoid B 0
                                        fumigatonoid C 0
                                        guignardone N 0
                                        liphagal 0
                                        novofumigatonin 0
                                        paraherquonin 0
                                        preaustinoid A 0
                                        preaustinoid A1 0
                                        preaustinoid A2 0
                                        preaustinoid A3 0
                                        protoaustinoid A 0
                                        protoaustinoid B 0
                                        salviol 0
                                        strongylophorine-26 0
                                        sugiol + 0
                                        terretonin 0
                                        yanuthones + 0
paths to the root