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ONTOLOGY REPORT - ANNOTATIONS


Term:levetiracetam
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Accession:CHEBI:6437 term browser browse the term
Definition:A pyrrolidinone and carboxamide that is N-methylpyrrolidin-2-one in which one of the methyl hydrogens is replaced by an aminocarbonyl group, while another is replaced by an ethyl group (the S enantiomer). An anticonvulsant, it is used for the treatment of epilepsy in both human and veterinary medicine.
Synonyms:exact_synonym: (2S)-2-(2-oxopyrrolidin-1-yl)butanamide
 related_synonym: (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide;   Formula=C8H14N2O2;   InChI=1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1;   InChIKey=HPHUVLMMVZITSG-LURJTMIESA-N;   Keppra;   SMILES=CC[C@H](N1CCCC1=O)C(N)=O;   UCB-L 059;   levetiracetamum
 xref: CAS:102767-28-2 "ChemIDplus";   CAS:102767-28-2 "KEGG COMPOUND";   DrugBank:DB01202;   Drug_Central:1563 "DrugCentral";   KEGG:C07841;   KEGG:D00709;   LINCS:LSM-5603
 xref_mesh: MESH:D000077287
 xref: PMID:22119754 "Europe PMC";   PMID:22321334 "Europe PMC";   Reaxys:8407472 "Reaxys";   VSDB:2979;   Wikipedia:Levetiracetam


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levetiracetam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Acvrl1 activin A receptor like type 1 JBrowse link 7 142,769,942 142,787,336 RGD:6480464
G Arhgef1 Rho guanine nucleotide exchange factor 1 JBrowse link 1 81,769,212 81,797,237 RGD:6480464
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 JBrowse link 10 85,954,138 85,974,764 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccnh cyclin H JBrowse link 2 13,593,100 13,613,910 RGD:6480464
G Chrm2 cholinergic receptor, muscarinic 2 JBrowse link 4 64,089,028 64,091,090 RGD:6480464
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Dao D-amino-acid oxidase JBrowse link 12 48,353,691 48,373,647 RGD:6480464
G Dbp D-box binding PAR bZIP transcription factor JBrowse link 1 101,687,896 101,692,845 RGD:6480464
G Des desmin JBrowse link 9 82,556,574 82,564,288 RGD:6480464
G Gle1 GLE1 RNA export mediator JBrowse link 3 8,498,098 8,530,218 RGD:6480464
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 JBrowse link 7 12,851,730 12,870,087 RGD:6480464
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:6480464
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:6480464
G Kcna4 potassium voltage-gated channel subfamily A member 4 JBrowse link 3 98,293,295 98,300,763 RGD:6480464
G Kctd3 potassium channel tetramerization domain containing 3 JBrowse link 13 107,433,588 107,471,843 RGD:6480464
G Khdrbs2 KH RNA binding domain containing, signal transduction associated 2 JBrowse link 9 39,501,431 40,008,707 RGD:6480464
G Lap3 leucine aminopeptidase 3 JBrowse link 14 70,102,813 70,121,797 RGD:6480464
G Lsm1 LSM1 homolog, mRNA degradation associated JBrowse link 16 71,046,475 71,057,883 RGD:6480464
G Mettl7b methyltransferase like 7B JBrowse link 7 3,383,876 3,386,522 RGD:6480464
G Nap1l2 nucleosome assembly protein 1-like 2 JBrowse link X 73,997,274 73,999,677 RGD:6480464
G Ngly1 N-glycanase 1 JBrowse link 15 10,405,453 10,455,973 RGD:6480464
G Phldb1 pleckstrin homology-like domain, family B, member 1 JBrowse link 8 48,997,189 49,045,176 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464
G Prkx protein kinase, X-linked JBrowse link X 45,080,963 45,125,095 RGD:6480464
G Psip1 PC4 and SFRS1 interacting protein 1 JBrowse link 5 101,555,691 101,588,659 RGD:6480464
G Serinc1 serine incorporator 1 JBrowse link 20 38,966,016 38,985,056 RGD:6480464
G Slc23a2 solute carrier family 23 member 2 JBrowse link 3 124,632,491 124,842,225 RGD:6480464
G Slc4a7 solute carrier family 4 member 7 JBrowse link 15 11,832,611 11,912,923 RGD:6480464
G Smc2 structural maintenance of chromosomes 2 JBrowse link 5 68,717,509 68,764,080 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Tent2 terminal nucleotidyltransferase 2 JBrowse link 2 22,746,290 22,798,252 RGD:6480464
G Trdmt1 tRNA aspartic acid methyltransferase 1 JBrowse link 17 80,824,652 80,859,585 RGD:6480464
G Vars2 valyl-tRNA synthetase 2, mitochondrial JBrowse link 20 3,588,462 3,599,514 RGD:6480464
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:6480464
G Zfp266 zinc finger protein 266 JBrowse link 8 21,511,831 21,543,275 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        xenobiotic 18178
          levetiracetam 41
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                lactam 2855
                                                  gamma-lactam 346
                                                    pyrrolidin-2-ones 131
                                                      levetiracetam 41
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.