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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-hydroxypicolinic acid
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Accession:CHEBI:64342 term browser browse the term
Definition:A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.
Synonyms:exact_synonym: 3-hydroxypyridine-2-carboxylic acid
 related_synonym: 3-hydroxy-2-pyridinecarboxylic acid;   Formula=C6H5NO3;   HPA;   InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10);   InChIKey=BRARRAHGNDUELT-UHFFFAOYSA-N;   SMILES=OC(=O)c1ncccc1O
 xref: CAS:874-24-8;   HMDB:HMDB0013188;   KEGG:C18620
 xref_mesh: MESH:C049246
 xref: PDBeChem:MHW;   PMID:5902481;   PMID:8457722;   Reaxys:118954;   Wikipedia:3-Hydroxypicolinic_acid


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3-hydroxypicolinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp1 matrix metallopeptidase 1 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP1 protein CTD PMID:21189019 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP2 protein CTD PMID:21189019 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP3 protein CTD PMID:21189019 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp8 matrix metallopeptidase 8 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP8 protein CTD PMID:21189019 NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520
JBrowse link

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  CHEBI ontology 19812
    role 19761
      application 19471
        MALDI matrix material 949
          3-hydroxypicolinic acid 4
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        monocarboxylic acid 17632
                                          3-hydroxypicolinic acid 4
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