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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-hydroxypicolinic acid
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Accession:CHEBI:64342 term browser browse the term
Definition:A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.
Synonyms:exact_synonym: 3-hydroxypyridine-2-carboxylic acid
 related_synonym: 3-hydroxy-2-pyridinecarboxylic acid;   Formula=C6H5NO3;   HPA;   InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10);   InChIKey=BRARRAHGNDUELT-UHFFFAOYSA-N;   SMILES=OC(=O)c1ncccc1O
 xref: CAS:874-24-8;   HMDB:HMDB0013188;   KEGG:C18620
 xref_mesh: MESH:C049246
 xref: PDBeChem:MHW;   PMID:5902481;   PMID:8457722;   Reaxys:118954;   Wikipedia:3-Hydroxypicolinic_acid


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3-hydroxypicolinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp1 matrix metallopeptidase 1 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP1 protein CTD PMID:21189019 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP2 protein CTD PMID:21189019 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP3 protein CTD PMID:21189019 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp8 matrix metallopeptidase 8 decreases activity ISO 3-hydroxypicolinic acid results in decreased activity of MMP8 protein CTD PMID:21189019 NCBI chr 8:5,768,808...5,777,741
Ensembl chr 8:5,768,811...5,778,702
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        MALDI matrix material 932
          3-hydroxypicolinic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        monocarboxylic acid 17406
                                          3-hydroxypicolinic acid 4
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