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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:isoprenaline
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Accession:CHEBI:64317 term browser browse the term
Definition:A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Synonyms:exact_synonym: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol
 related_synonym: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol;   1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol;   3,4-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol;   Formula=C11H17NO3;   InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3;   InChIKey=JWZZKOKVBUJMES-UHFFFAOYSA-N;   N-isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine;   N-isopropylnoradrenaline;   N-isopropylnorepinephrine;   SMILES=CC(C)NCC(O)c1ccc(O)c(O)c1;   alpha-(isopropylaminomethyl)protocatechuyl alcohol;   isoprenalina;   isoprenalinum;   isopropyl noradrenaline;   isoproterenol
 xref: CAS:7683-59-2;   DrugBank:DB01064;   Drug_Central:1499;   KEGG:C07056;   KEGG:D08090;   LINCS:LSM-4311
 xref_mesh: MESH:D007545
 xref: Patent:DE723278;   Patent:US2308232;   Reaxys:2213857;   Wikipedia:Isoprenaline


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isoprenaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin increases expression ISO Isoproterenol results in increased expression of A2M mRNA CTD PMID:21335049 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229 		JBrowse link
G ABCA1 ATP binding cassette subfamily A member 1 increases expression ISO Isoproterenol results in increased expression of ABCA1 mRNA CTD PMID:20003209 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 increases expression ISO Isoproterenol results in increased expression of ABCB1A mRNA CTD PMID:20003209 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB4 ATP binding cassette subfamily B member 4 decreases expression ISO
EXP		 Isoproterenol results in decreased expression of ABCB4 mRNA CTD PMID:24286936 NCBI chr 7:87,365,896...87,476,027
Ensembl chr 7:87,401,696...87,480,435 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 decreases expression
increases expression		 ISO
EXP		 Isoproterenol results in decreased expression of ABCC3 mRNA
Isoproterenol results in increased expression of ABCC3 mRNA		 CTD PMID:21335049 PMID:24286936 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) increases expression ISO Isoproterenol results in increased expression of ABCC4 mRNA CTD PMID:20003209 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) increases expression ISO Isoproterenol results in increased expression of ABCG2 mRNA CTD PMID:20003209 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABHD2 abhydrolase domain containing 2, acylglycerol lipase increases expression ISO Isoproterenol results in increased expression of ABHD2 mRNA CTD PMID:20211217 NCBI chr15:89,040,998...89,202,355
Ensembl chr15:89,087,459...89,202,355 		JBrowse link
G ABHD4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Isoproterenol results in increased expression of ABHD4 mRNA CTD PMID:20003209 NCBI chr14:22,598,300...22,612,963
Ensembl chr14:22,598,290...22,612,963 		JBrowse link
G ABI3 ABI family member 3 increases expression ISO Isoproterenol results in increased expression of ABI3 mRNA CTD PMID:20003209 NCBI chr17:49,210,707...49,223,225
Ensembl chr17:49,210,411...49,223,225 		JBrowse link
G ABLIM3 actin binding LIM protein family member 3 increases expression ISO Isoproterenol results in increased expression of ABLIM3 mRNA CTD PMID:20003209 NCBI chr 5:149,141,493...149,260,542
Ensembl chr 5:149,141,483...149,260,542 		JBrowse link
G ACACA acetyl-CoA carboxylase alpha multiple interactions
decreases phosphorylation
increases phosphorylation		 ISO triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of ACACA protein]
Isoproterenol results in decreased phosphorylation of ACACA protein		 CTD PMID:18390901 PMID:27491814 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain multiple interactions
decreases expression		 ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADL mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]] CTD PMID:25045214 PMID:30303030 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain decreases activity
multiple interactions
decreases expression		 ISO Isoproterenol results in decreased activity of ACADM protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADM mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]]		 CTD PMID:19826179 PMID:25045214 PMID:30303030 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACADS acyl-CoA dehydrogenase short chain multiple interactions
decreases expression		 ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADS mRNA
Isoproterenol results in decreased expression of ACADS mRNA		 CTD PMID:30303030 NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of ACADVL mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADVL mRNA		 CTD PMID:30303030 NCBI chr17:7,217,125...7,225,266
Ensembl chr17:7,217,125...7,225,266 		JBrowse link
G ACE angiotensin I converting enzyme multiple interactions
increases activity		 ISO oleuropein inhibits the reaction [Isoproterenol results in increased activity of ACE protein] CTD PMID:26056852 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 increases expression
decreases activity
multiple interactions		 ISO Isoproterenol results in increased expression of ACE2 mRNA
Isoproterenol results in decreased activity of ACE2 protein
[Isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7); xanthone inhibits the reaction [[Isoproterenol results in decreased activity of ACE2 protein] which results in decreased abundance of angiotensin I (1-7)]; xanthone inhibits the reaction [Isoproterenol results in decreased activity of ACE2 protein]
Isoproterenol results in increased expression of ACE2 protein		 CTD PMID:20003209 PMID:20409916 PMID:36414029 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACER2 alkaline ceramidase 2 increases expression ISO Isoproterenol results in increased expression of ACER2 mRNA CTD PMID:20003209 NCBI chr 9:19,409,009...19,452,505
Ensembl chr 9:19,409,009...19,452,505 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACSL1 mRNA CTD PMID:30303030 NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818 		JBrowse link
G ACTA1 actin alpha 1, skeletal muscle multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA] CTD PMID:10710348 NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,104 		JBrowse link
G ACTA2 actin alpha 2, smooth muscle multiple interactions
increases expression
decreases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of ACTA2 mRNA]
Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of ACTA2 protein]
Isoproterenol results in increased expression of ACTA2 mRNA; Isoproterenol results in increased expression of ACTA2 protein		 CTD PMID:18089841 PMID:20003209 PMID:24945829 PMID:28526319 PMID:35305975 More... NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G ACTB actin beta decreases expression ISO Isoproterenol results in decreased expression of ACTB mRNA CTD PMID:20003209 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ACTG2 actin gamma 2, smooth muscle increases expression ISO Isoproterenol results in increased expression of ACTG2 mRNA CTD PMID:21335049 NCBI chr 2:73,893,008...73,919,865
Ensembl chr 2:73,892,314...73,919,865 		JBrowse link
G ADA adenosine deaminase multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ADA mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 multiple interactions
increases expression		 ISO bellidifolin inhibits the reaction [Isoproterenol results in increased expression of ADAM17 mRNA] CTD PMID:37528096 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAM22 ADAM metallopeptidase domain 22 increases expression ISO Isoproterenol results in increased expression of ADAM22 mRNA CTD PMID:20003209 NCBI chr 7:87,934,251...88,202,889
Ensembl chr 7:87,934,143...88,202,889 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 increases expression ISO Isoproterenol results in increased expression of ADAM8 mRNA CTD PMID:20211217 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G ADAMTSL2 ADAMTS like 2 increases expression ISO Isoproterenol results in increased expression of ADAMTSL2 mRNA CTD PMID:20003209 NCBI chr 9:133,532,164...133,575,519
Ensembl chr 9:133,532,164...133,575,519 		JBrowse link
G ADAMTSL4 ADAMTS like 4 increases expression ISO Isoproterenol results in increased expression of ADAMTSL4 mRNA CTD PMID:20003209 NCBI chr 1:150,549,408...150,560,937
Ensembl chr 1:150,549,369...150,560,937 		JBrowse link
G ADCY5 adenylate cyclase 5 increases response to substance
multiple interactions		 ISO ADCY5 protein results in increased susceptibility to Isoproterenol
[ADCY5 protein results in increased susceptibility to Isoproterenol] which results in decreased expression of SOD2 protein; SOD2 protein inhibits the reaction [ADCY5 protein results in increased susceptibility to Isoproterenol]		 CTD PMID:12869393 PMID:23536361 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADCY6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Isoproterenol CTD PMID:12393090 NCBI chr12:48,766,194...48,789,974
Ensembl chr12:48,766,194...48,789,089 		JBrowse link
G ADCY9 adenylate cyclase 9 multiple interactions EXP [Isoproterenol co-treated with Miconazole] results in increased activity of ADCY9 protein alternative form CTD PMID:30607468 NCBI chr16:3,953,387...4,116,442
Ensembl chr16:3,953,387...4,116,442 		JBrowse link
G ADD3 adducin 3 decreases expression ISO Isoproterenol results in decreased expression of ADD3 mRNA CTD PMID:21335049 NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565 		JBrowse link
G ADGRD1 adhesion G protein-coupled receptor D1 increases expression ISO Isoproterenol results in increased expression of ADGRD1 mRNA CTD PMID:20003209 NCBI chr12:130,953,907...131,141,469
Ensembl chr12:130,953,907...131,141,469 		JBrowse link
G ADGRF5 adhesion G protein-coupled receptor F5 increases expression ISO Isoproterenol results in increased expression of ADGRF5 mRNA CTD PMID:20003209 NCBI chr 6:46,852,522...46,954,939
Ensembl chr 6:46,852,522...46,954,943 		JBrowse link
G ADGRL4 adhesion G protein-coupled receptor L4 increases expression ISO Isoproterenol results in increased expression of ADGRL4 mRNA CTD PMID:20003209 NCBI chr 1:78,889,764...79,006,730
Ensembl chr 1:78,889,764...79,282,124 		JBrowse link
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression ISO Isoproterenol results in increased expression of ADH1 mRNA CTD PMID:20003209 NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746 		JBrowse link
G ADM adrenomedullin multiple interactions
increases expression		 ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM mRNA; [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM protein; ADM protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]
Isoproterenol results in increased expression of ADM mRNA; Isoproterenol results in increased expression of ADM protein		 CTD PMID:12732346 PMID:17250927 PMID:17306419 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADRA1B adrenoceptor alpha 1B multiple interactions
decreases expression		 ISO ADRA1B protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRA1B mRNA		 CTD PMID:12649302 PMID:20003209 NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012 		JBrowse link
G ADRB1 adrenoceptor beta 1 multiple interactions
decreases expression
increases phosphorylation
increases activity
affects response to substance
increases uptake		 EXP
ISO		 [Isoproterenol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; Atenolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 12177 inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB1 protein results in increased abundance of Cyclic AMP]; Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]
Isoproterenol results in decreased expression of ADRB1 mRNA
Isoproterenol results in increased phosphorylation of ADRB1 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
ADRB1 protein polymorphism affects the susceptibility to Isoproterenol
Isoproterenol results in increased uptake of ADRB1 protein
ADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]; ADRB1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Metoprolol inhibits the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]
Isoproterenol results in decreased expression of ADRB1; Isoproterenol results in decreased expression of ADRB1 mRNA		 CTD PMID:1312942 PMID:8096834 PMID:8723169 PMID:11159692 PMID:12761341 More... NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 multiple interactions
increases activity
affects expression
increases uptake
decreases expression
increases phosphorylation
increases expression		 EXP
ISO		 4-(1H-imidazol-4-ylmethyl)piperidine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Isoproterenol results in increased activity of ADRB2 protein] which results in increased chemical synthesis of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol; Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; clobenpropit promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Cobalt promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Histamine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]; imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Isoproterenol binds to and results in increased activity of ADRB2 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; Ketotifen inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Zinc promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]
Isoproterenol affects the expression of ADRB2 mRNA
Isoproterenol results in increased uptake of ADRB2 protein
[Isoproterenol results in increased activity of ADRB2 protein] which results in increased secretion of Histamine; ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRB2; Isoproterenol results in decreased expression of ADRB2 mRNA
[GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein; ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]
Isoproterenol results in increased phosphorylation of ADRB2 protein
Isoproterenol results in increased expression of ADRB2 mRNA		 CTD PMID:9875846 PMID:10226872 PMID:10516654 PMID:11164953 PMID:11752207 More... NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 multiple interactions
increases activity
increases expression		 EXP
ISO		 [Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Isoproterenol binds to and results in increased activity of ADRB3 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB3 protein]; L 748,337 inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]
Isoproterenol results in increased expression of ADRB3 mRNA; Isoproterenol results in increased expression of ADRB3 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]; 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased expression of ADRB3 protein]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 mRNA]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 protein]; Isoproterenol binds to and results in increased activity of ADRB3 protein		 CTD PMID:1682311 PMID:7815362 PMID:11159692 PMID:14730417 PMID:15009959 More... NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AEN apoptosis enhancing nuclease decreases expression ISO Isoproterenol results in decreased expression of AEN mRNA CTD PMID:20003209 NCBI chr15:88,604,683...88,632,281
Ensembl chr15:88,621,337...88,632,281 		JBrowse link
G AGBL5 AGBL carboxypeptidase 5 decreases expression ISO Isoproterenol results in decreased expression of AGBL5 mRNA CTD PMID:20003209 NCBI chr 2:27,050,364...27,070,618
Ensembl chr 2:27,042,364...27,070,622 		JBrowse link
G AGT angiotensinogen multiple interactions
increases expression		 ISO
EXP		 adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; ICI 118551 inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]; Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]
Isoproterenol results in increased expression of AGT protein
AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]; AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Losartan promotes the reaction [Isoproterenol results in increased expression of AGT protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril promotes the reaction [Isoproterenol results in increased expression of AGT protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; trandolapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of AGT protein]
Isoproterenol results in increased expression of AGT mRNA; Isoproterenol results in increased expression of AGT protein
Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein]		 CTD PMID:1534315 PMID:1653766 PMID:7843740 PMID:11709406 PMID:16731636 More... NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 decreases expression ISO Isoproterenol results in decreased expression of AGTR1A mRNA CTD PMID:17350036 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AHCY adenosylhomocysteinase increases expression ISO Isoproterenol results in increased expression of AHCY mRNA CTD PMID:20003209 NCBI chr20:34,231,981...34,311,836
Ensembl chr20:34,280,268...34,311,802 		JBrowse link
G AHNAK2 AHNAK nucleoprotein 2 increases expression ISO Isoproterenol results in increased expression of AHNAK2 mRNA CTD PMID:20003209 NCBI chr14:104,937,253...104,978,374
Ensembl chr14:104,937,244...104,978,374 		JBrowse link
G AHR aryl hydrocarbon receptor increases expression
decreases expression		 EXP
ISO		 Isoproterenol results in increased expression of AHR mRNA
Isoproterenol results in decreased expression of AHR mRNA		 CTD PMID:24286936 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AHSG alpha 2-HS glycoprotein increases expression ISO Isoproterenol results in increased expression of AHSG mRNA CTD PMID:20003209 PMID:21335049 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318 		JBrowse link
G AIF1 allograft inflammatory factor 1 decreases expression ISO Isoproterenol results in decreased expression of AIF1 mRNA CTD PMID:20003209 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AK4 adenylate kinase 4 decreases expression ISO Isoproterenol results in decreased expression of AK4 mRNA CTD PMID:20003209 NCBI chr 1:65,147,552...65,232,145
Ensembl chr 1:65,147,549...65,232,145 		JBrowse link
G AKAP1 A-kinase anchoring protein 1 decreases expression ISO Isoproterenol results in decreased expression of AKAP1 mRNA CTD PMID:20003209 NCBI chr17:57,085,246...57,121,344
Ensembl chr17:57,085,092...57,121,346 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 increases expression ISO Isoproterenol results in increased expression of AKAP13 mRNA CTD PMID:20003209 NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 increases phosphorylation
decreases phosphorylation
multiple interactions
decreases expression		 ISO Isoproterenol results in increased phosphorylation of AKT1 protein
Isoproterenol results in decreased phosphorylation of AKT1 protein
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased phosphorylation of AKT1 protein]; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AKT1 mRNA; [PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; Enalapril promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]
Isoproterenol results in decreased expression of AKT1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]; Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]		 CTD PMID:15178407 PMID:15618457 PMID:15951400 PMID:16716347 PMID:17623046 More... NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases expression ISO Isoproterenol results in decreased expression of ALDH2 mRNA CTD PMID:20003209 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALDH3A2 aldehyde dehydrogenase 3 family member A2 decreases expression ISO Isoproterenol results in decreased expression of ALDH3A2 mRNA CTD PMID:21335049 NCBI chr17:19,648,136...19,677,596
Ensembl chr17:19,648,136...19,685,760 		JBrowse link
G ALPK2 alpha kinase 2 increases expression ISO Isoproterenol results in increased expression of ALPK2 mRNA CTD PMID:20003209 NCBI chr18:58,481,247...58,629,091
Ensembl chr18:58,481,247...58,629,091 		JBrowse link
G ALPK3 alpha kinase 3 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of ALPK3 mRNA; Isoproterenol results in decreased expression of ALPK3 protein
MIR384 mRNA inhibits the reaction [Isoproterenol results in decreased expression of ALPK3 mRNA]		 CTD PMID:35510648 NCBI chr15:84,817,356...84,873,479
Ensembl chr15:84,817,356...84,873,479 		JBrowse link
G ALPP alkaline phosphatase, placental multiple interactions
increases expression		 EXP Amphetamine promotes the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Chlorpromazine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; norfluoxetine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 2:232,378,751...232,382,889
Ensembl chr 2:232,378,724...232,382,889 		JBrowse link
G AMY2B amylase alpha 2B multiple interactions ISO Atenolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein]; Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein; Propranolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 1:103,554,644...103,579,534
Ensembl chr 1:103,553,815...103,579,534 		JBrowse link
G ANG angiogenin increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of ANG mRNA
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ANG mRNA]		 CTD PMID:18089841 PMID:20003209 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971 		JBrowse link
G ANGPT2 angiopoietin 2 increases expression ISO Isoproterenol results in increased expression of ANGPT2 mRNA CTD PMID:22908232 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G ANGPTL2 angiopoietin like 2 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL2 mRNA CTD PMID:20003209 NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635 		JBrowse link
G ANGPTL6 angiopoietin like 6 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL6 mRNA CTD PMID:21335049 NCBI chr19:10,092,338...10,106,190
Ensembl chr19:10,092,338...10,102,678 		JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A decreases expression ISO Isoproterenol results in decreased expression of ANP32A mRNA CTD PMID:20003209 PMID:21335049 NCBI chr15:68,778,535...68,820,895
Ensembl chr15:68,778,535...68,820,897 		JBrowse link
G ANXA1 annexin A1 multiple interactions
increases expression		 ISO ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]
Isoproterenol results in increased expression of ANXA1 mRNA		 CTD PMID:16835395 PMID:20003209 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G AOC1 amine oxidase copper containing 1 multiple interactions
increases activity		 ISO Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; H 35-25 inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; pimagedine inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein] CTD PMID:2860926 PMID:6218830 NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504 		JBrowse link
G AOC3 amine oxidase copper containing 3 increases expression ISO Isoproterenol results in increased expression of AOC3 mRNA CTD PMID:20003209 NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130 		JBrowse link
G AOX1 aldehyde oxidase 1 increases expression ISO Isoproterenol results in increased expression of AOX1 mRNA CTD PMID:20003209 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G AP1B1 adaptor related protein complex 1 subunit beta 1 increases expression ISO Isoproterenol results in increased expression of AP1B1 mRNA CTD PMID:21335049 NCBI chr22:29,327,680...29,388,570
Ensembl chr22:29,327,680...29,388,583 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 increases expression EXP Isoproterenol results in increased expression of APAF1 mRNA CTD PMID:24286936 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Isoproterenol results in increased expression of APEX1 mRNA CTD PMID:21335049 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APLN apelin multiple interactions
decreases expression		 ISO Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN mRNA]; Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN protein]
Isoproterenol results in decreased expression of APLN mRNA; Isoproterenol results in decreased expression of APLN protein		 CTD PMID:19960946 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956 		JBrowse link
G APOA2 apolipoprotein A2 increases expression ISO Isoproterenol results in increased expression of APOA2 mRNA CTD PMID:21335049 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOD apolipoprotein D increases expression ISO Isoproterenol results in increased expression of APOD mRNA CTD PMID:20003209 NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033 		JBrowse link
G APPBP2 amyloid beta precursor protein binding protein 2 increases expression ISO Isoproterenol results in increased expression of APPBP2 mRNA CTD PMID:20003209 NCBI chr17:60,443,158...60,526,242
Ensembl chr17:60,443,158...60,526,242 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO Isoproterenol results in increased expression of APPL2 mRNA CTD PMID:20003209 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203 		JBrowse link
G ARF4 ADP ribosylation factor 4 increases expression ISO Isoproterenol results in increased expression of ARF4 mRNA CTD PMID:21335049 NCBI chr 3:57,571,363...57,597,344
Ensembl chr 3:57,571,363...57,598,220 		JBrowse link
G ARHGAP12 Rho GTPase activating protein 12 increases expression ISO Isoproterenol results in increased expression of ARHGAP12 mRNA CTD PMID:20003209 NCBI chr10:31,805,398...31,928,876
Ensembl chr10:31,805,398...31,928,876 		JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 decreases expression ISO Isoproterenol results in decreased expression of ARHGAP18 mRNA CTD PMID:20003209 NCBI chr 6:129,576,132...129,710,177
Ensembl chr 6:129,576,132...129,710,177 		JBrowse link
G ARHGAP20 Rho GTPase activating protein 20 increases expression ISO Isoproterenol results in increased expression of ARHGAP20 mRNA CTD PMID:20003209 NCBI chr11:110,577,043...110,713,189
Ensembl chr11:110,577,042...110,713,189 		JBrowse link
G ARHGAP24 Rho GTPase activating protein 24 increases expression ISO Isoproterenol results in increased expression of ARHGAP24 mRNA CTD PMID:20003209 NCBI chr 4:85,475,150...86,002,666
Ensembl chr 4:85,475,150...86,002,668 		JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta increases expression ISO Isoproterenol results in increased expression of ARHGDIB mRNA CTD PMID:30303030 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728 		JBrowse link
G ARID4B AT-rich interaction domain 4B increases expression ISO Isoproterenol results in increased expression of ARID4B mRNA CTD PMID:20003209 NCBI chr 1:235,166,902...235,328,179
Ensembl chr 1:235,131,634...235,328,219 		JBrowse link
G ARID5B AT-rich interaction domain 5B increases expression ISO Isoproterenol results in increased expression of ARID5B mRNA CTD PMID:20003209 NCBI chr10:61,901,699...62,096,944
Ensembl chr10:61,901,684...62,096,944 		JBrowse link
G ARL17B ADP ribosylation factor like GTPase 17B decreases expression ISO Isoproterenol results in decreased expression of ARF2 mRNA CTD PMID:20003209 NCBI chr17:46,274,184...46,361,787
Ensembl chr17:46,274,784...46,361,766
Ensembl chr17:46,274,784...46,361,766 		JBrowse link
G ARL4A ADP ribosylation factor like GTPase 4A increases expression ISO Isoproterenol results in increased expression of ARL4A mRNA CTD PMID:20003209 NCBI chr 7:12,686,903...12,690,958
Ensembl chr 7:12,686,856...12,690,958 		JBrowse link
G ARNT2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of ARNT2 mRNA
Isoproterenol results in increased expression of ARNT2 mRNA		 CTD PMID:24286936 NCBI chr15:80,404,382...80,597,933
Ensembl chr15:80,404,350...80,597,933 		JBrowse link
G ARRB1 arrestin beta 1 multiple interactions EXP Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein] CTD PMID:18787115 NCBI chr11:75,260,122...75,351,661
Ensembl chr11:75,260,122...75,351,705 		JBrowse link
G ARRB2 arrestin beta 2 affects localization
multiple interactions		 EXP
ISO		 Isoproterenol affects the localization of ARRB2 protein
ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; S-nitrosocysteine inhibits the reaction [Isoproterenol affects the localization of ARRB2 protein]		 CTD PMID:17482545 PMID:17925438 PMID:18787115 PMID:21078978 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ARRDC2 arrestin domain containing 2 increases expression ISO Isoproterenol results in increased expression of ARRDC2 mRNA CTD PMID:20003209 NCBI chr19:18,001,124...18,014,102
Ensembl chr19:18,001,132...18,014,102 		JBrowse link
G ARRDC3 arrestin domain containing 3 increases expression ISO Isoproterenol results in increased expression of ARRDC3 mRNA CTD PMID:20003209 NCBI chr 5:91,368,631...91,383,317
Ensembl chr 5:91,368,631...91,383,317 		JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression ISO Isoproterenol results in decreased expression of ASAP1 mRNA CTD PMID:20003209 NCBI chr 8:130,052,104...130,443,674
Ensembl chr 8:130,052,104...130,443,674 		JBrowse link
G ASB11 ankyrin repeat and SOCS box containing 11 increases expression ISO Isoproterenol results in increased expression of ASB11 mRNA CTD PMID:20003209 NCBI chr  X:15,281,697...15,315,640
Ensembl chr  X:15,281,697...15,315,640 		JBrowse link
G ASCC3 activating signal cointegrator 1 complex subunit 3 increases expression ISO Isoproterenol results in increased expression of ASCC3 mRNA CTD PMID:20003209 NCBI chr 6:100,508,194...100,881,329
Ensembl chr 6:100,508,194...100,881,372 		JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Isoproterenol results in increased expression of ASNS mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542 		JBrowse link
G ASPH aspartate beta-hydroxylase decreases expression ISO Isoproterenol results in decreased expression of ASPH mRNA CTD PMID:20003209 NCBI chr 8:61,500,556...61,714,592
Ensembl chr 8:61,500,556...61,714,640 		JBrowse link
G ASPN asporin increases expression ISO Isoproterenol results in increased expression of ASPN mRNA CTD PMID:20003209 NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506 		JBrowse link
G ATAD2 ATPase family AAA domain containing 2 increases expression ISO Isoproterenol results in increased expression of ATAD2 mRNA CTD PMID:20003209 NCBI chr 8:123,319,850...123,416,350
Ensembl chr 8:123,319,850...123,416,350 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions
increases phosphorylation		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of ATF2 protein] CTD PMID:18089841 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATF3 activating transcription factor 3 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of ATF3 mRNA
Isoproterenol results in increased expression of ATF3 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of ATF3 protein]		 CTD PMID:21823215 PMID:25136830 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATP10D ATPase phospholipid transporting 10D (putative) increases expression ISO Isoproterenol results in increased expression of ATP10D mRNA CTD PMID:20003209 NCBI chr 4:47,485,275...47,593,486
Ensembl chr 4:47,485,275...47,593,486 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression		 ISO astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein]; astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 mRNA]; candesartan inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 protein]; Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein
Isoproterenol results in decreased expression of ATP2A2 mRNA; Isoproterenol results in decreased expression of ATP2A2 protein		 CTD PMID:16723803 PMID:17509559 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha multiple interactions
decreases expression		 ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1A mRNA
Isoproterenol results in decreased expression of ATP5F1A mRNA		 CTD PMID:20003209 PMID:30303030 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G ATP5F1D ATP synthase F1 subunit delta multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1D mRNA CTD PMID:30303030 NCBI chr19:1,241,751...1,244,825
Ensembl chr19:1,241,746...1,244,825 		JBrowse link
G ATP5MC1 ATP synthase membrane subunit c locus 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5MC1 mRNA CTD PMID:30303030 NCBI chr17:48,892,787...48,895,871
Ensembl chr17:48,892,765...48,895,871 		JBrowse link
G ATP5ME ATP synthase membrane subunit e multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5ME mRNA CTD PMID:30303030 NCBI chr 4:672,436...674,276
Ensembl chr 4:672,436...674,330 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5PD mRNA CTD PMID:30303030 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985 		JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5PO mRNA CTD PMID:30303030 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP6AP2 mRNA CTD PMID:30303030 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848 		JBrowse link
G ATP6V1E1 ATPase H+ transporting V1 subunit E1 decreases expression ISO Isoproterenol results in decreased expression of ATP6V1E1 mRNA CTD PMID:20003209 NCBI chr22:17,592,136...17,628,822
Ensembl chr22:17,592,136...17,628,749 		JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 increases expression ISO Isoproterenol results in increased expression of ATP8B1 mRNA CTD PMID:20003209 NCBI chr18:57,646,426...57,803,315
Ensembl chr18:57,646,426...57,803,315 		JBrowse link
G ATXN10 ataxin 10 increases expression ISO Isoproterenol results in increased expression of ATXN10 mRNA CTD PMID:20003209 NCBI chr22:45,671,834...45,845,307
Ensembl chr22:45,671,798...45,845,307 		JBrowse link
G AUTS2 activator of transcription and developmental regulator AUTS2 decreases expression ISO Isoproterenol results in decreased expression of AUTS2 mRNA CTD PMID:20003209 NCBI chr 7:69,598,475...70,793,506
Ensembl chr 7:69,598,296...70,793,506 		JBrowse link
G AZI2 5-azacytidine induced 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of AZI2 mRNA CTD PMID:30303030 NCBI chr 3:28,321,047...28,348,824
Ensembl chr 3:28,315,003...28,349,050 		JBrowse link
G BAG1 BAG cochaperone 1 decreases expression ISO Isoproterenol results in decreased expression of BAG1 mRNA CTD PMID:21335049 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720 		JBrowse link
G BAG4 BAG cochaperone 4 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of BAG4 mRNA CTD PMID:30303030 NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 decreases expression EXP Isoproterenol results in decreased expression of BAK1 mRNA CTD PMID:24286936 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of BAX protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]
Isoproterenol results in decreased expression of BAX mRNA
Isoproterenol results in increased expression of BAX mRNA; Isoproterenol results in increased expression of BAX protein		 CTD PMID:15052282 PMID:16116328 PMID:17961425 PMID:24286936 PMID:24954035 More... NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 increases expression ISO Isoproterenol results in increased expression of BCAT1 mRNA CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression
multiple interactions
increases expression		 ISO Isoproterenol results in decreased expression of BCL2 protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein; [erdosteine co-treated with Isoproterenol] affects the expression of BCL2 protein; [Isoproterenol co-treated with POSTN protein] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of BCL2 mRNA]; Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; echinocystic acid affects the reaction [Isoproterenol affects the expression of BCL2 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]
Isoproterenol results in decreased expression of BCL2 mRNA; Isoproterenol results in decreased expression of BCL2 protein		 CTD PMID:11218852 PMID:12791704 PMID:15052282 PMID:19573579 PMID:24954035 More... NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 increases expression
decreases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of BCL2L1 mRNA
Isoproterenol results in decreased expression of BCL2L1 mRNA; Isoproterenol results in decreased expression of BCL2L1 protein
Isoproterenol results in increased expression of BCL2L1 mRNA alternative form; Isoproterenol results in increased expression of BCL2L1 protein; Isoproterenol results in increased expression of BCL2L1 protein alternative form
Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]; Metoprolol inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; Perindopril inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 mRNA alternative form]; Thymol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]		 CTD PMID:12738230 PMID:16116328 PMID:20003209 PMID:24286936 PMID:26996544 More... NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BCL2L11 BCL2 like 11 increases expression ISO
EXP		 Isoproterenol results in increased expression of BCL2L11 protein
Isoproterenol results in increased expression of BCL2L11 mRNA		 CTD PMID:14996839 PMID:24286936 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444 		JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 increases expression ISO Isoproterenol results in increased expression of BDH1 mRNA CTD PMID:20003209 NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323 		JBrowse link
G BICD1 BICD cargo adaptor 1 increases expression ISO Isoproterenol results in increased expression of BICD1 mRNA CTD PMID:20003209 NCBI chr12:32,106,847...32,383,633
Ensembl chr12:32,106,835...32,383,633 		JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of BIRC2 mRNA CTD PMID:30303030 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670 		JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 increases expression ISO Isoproterenol results in increased expression of BMAL1 mRNA CTD PMID:20003209 NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266 		JBrowse link
G BMF Bcl2 modifying factor increases expression ISO Isoproterenol results in increased expression of BMF mRNA CTD PMID:24286936 NCBI chr15:40,087,890...40,108,879
Ensembl chr15:40,087,890...40,108,892 		JBrowse link
G BMP10 bone morphogenetic protein 10 decreases response to substance
multiple interactions		 EXP
ISO		 BMP10 protein results in decreased susceptibility to Isoproterenol
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol]
BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]		 CTD PMID:31712309 NCBI chr 2:68,860,909...68,871,397
Ensembl chr 2:68,860,909...68,871,397 		JBrowse link
G BMP2 bone morphogenetic protein 2 increases expression ISO isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP4 bone morphogenetic protein 4 increases expression ISO isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP7 bone morphogenetic protein 7 increases expression ISO isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G BNIP1 BCL2 interacting protein 1 increases expression ISO Isoproterenol results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr 5:173,144,531...173,164,387
Ensembl chr 5:173,144,442...173,164,387 		JBrowse link
G BNIP3 BCL2 interacting protein 3 increases expression ISO Isoproterenol results in increased expression of BNIP3 mRNA CTD PMID:20003209 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK decreases expression ISO Isoproterenol results in decreased expression of BOK mRNA CTD PMID:21335049 NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,424...241,574,131 		JBrowse link
G BRD4 bromodomain containing 4 decreases expression
multiple interactions
increases expression		 ISO Isoproterenol results in decreased expression of BRD4 mRNA
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 protein]
Isoproterenol results in increased expression of BRD4 mRNA; Isoproterenol results in increased expression of BRD4 protein		 CTD PMID:20003209 PMID:37528096 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545 		JBrowse link
G BRWD1 bromodomain and WD repeat domain containing 1 increases expression ISO Isoproterenol results in increased expression of BRWD1 mRNA CTD PMID:20003209 NCBI chr21:39,184,176...39,321,212
Ensembl chr21:39,184,176...39,321,559 		JBrowse link
G BSDC1 BSD domain containing 1 increases expression ISO Isoproterenol results in increased expression of BSDC1 mRNA CTD PMID:20003209 NCBI chr 1:32,364,633...32,394,441
Ensembl chr 1:32,364,633...32,394,731 		JBrowse link
G C3 complement C3 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of C3 mRNA
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C3 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of C3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C3 protein]
Isoproterenol results in decreased expression of C3 mRNA
Isoproterenol results in increased expression of C3 mRNA; Isoproterenol results in increased expression of C3 protein		 CTD PMID:20003209 PMID:24286936 PMID:32924446 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G C4B complement C4B (Chido/Rodgers blood group) increases expression ISO Isoproterenol results in increased expression of C4B mRNA CTD PMID:20003209 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418 		JBrowse link
G C5 complement C5 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C5 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of C5 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C5 protein] CTD PMID:32924446 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,932,987...121,075,195 		JBrowse link
G C9 complement C9 increases expression ISO Isoproterenol results in increased expression of C9 mRNA CTD PMID:24286936 NCBI chr 5:39,284,140...39,364,495
Ensembl chr 5:39,284,140...39,371,324 		JBrowse link
G CA4 carbonic anhydrase 4 increases expression ISO Isoproterenol results in increased expression of CAR4 mRNA CTD PMID:20003209 NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C increases expression ISO Isoproterenol results in increased expression of CACNA1C mRNA CTD PMID:17526999 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950 		JBrowse link
G CADM4 cell adhesion molecule 4 decreases expression ISO Isoproterenol results in decreased expression of CADM4 mRNA CTD PMID:20003209 NCBI chr19:43,622,368...43,641,984
Ensembl chr19:43,622,368...43,639,850 		JBrowse link
G CALCA calcitonin related polypeptide alpha multiple interactions ISO CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]] CTD PMID:17306419 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CALCRL calcitonin receptor like receptor multiple interactions
increases expression		 ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of CALCRL mRNA
Isoproterenol results in increased expression of CALCRL mRNA; Isoproterenol results in increased expression of CALCRL protein		 CTD PMID:16987513 PMID:17250927 PMID:17306419 NCBI chr 2:187,341,964...187,448,252
Ensembl chr 2:187,341,964...187,448,460 		JBrowse link
G CALM3 calmodulin 3 decreases expression ISO Isoproterenol results in decreased expression of CALM3 mRNA CTD PMID:20003209 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782 		JBrowse link
G CALR calreticulin increases expression ISO Isoproterenol results in increased expression of CALR mRNA CTD PMID:21823215 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489 		JBrowse link
G CALR3 calreticulin 3 increases expression ISO Isoproterenol results in increased expression of CALR3 mRNA CTD PMID:20003209 NCBI chr19:16,479,061...16,496,167
Ensembl chr19:16,479,061...16,496,167 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta increases expression ISO Isoproterenol results in increased expression of CAMK2B mRNA CTD PMID:20003209 NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CAMK2D protein
[Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]		 CTD PMID:26982530 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927 		JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 decreases phosphorylation ISO Isoproterenol results in decreased phosphorylation of CAMKK2 protein CTD PMID:27491814 NCBI chr12:121,237,692...121,297,819
Ensembl chr12:121,237,675...121,298,308 		JBrowse link
G CAPN1 calpain 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CAPN1 mRNA
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN1 mRNA]		 CTD PMID:27527349 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006 		JBrowse link
G CAPN10 calpain 10 increases expression ISO Isoproterenol results in increased expression of CAPN10 mRNA CTD PMID:20003209 NCBI chr 2:240,586,734...240,599,104
Ensembl chr 2:240,586,734...240,617,705 		JBrowse link
G CAPN2 calpain 2 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CAPN2 mRNA
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN2 mRNA]		 CTD PMID:27527349 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018 		JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 increases expression ISO Isoproterenol results in increased expression of CARMIL1 mRNA CTD PMID:20003209 NCBI chr 6:25,279,374...25,620,530
Ensembl chr 6:25,279,078...25,620,530 		JBrowse link
G CASP1 caspase 1 decreases expression
increases expression		 EXP Isoproterenol results in decreased expression of CASP1 mRNA
Isoproterenol results in increased expression of CASP1 mRNA		 CTD PMID:24286936 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP2 caspase 2 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of CASP2 mRNA
Isoproterenol results in increased expression of CASP2 mRNA		 CTD PMID:24286936 NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity		 EXP
ISO		 Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein
Isoproterenol results in increased cleavage of CASP3 protein
Isoproterenol results in increased activity of CASP3 protein
[Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; [erdosteine co-treated with Isoproterenol] affects the expression of CASP3 protein; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; anethole inhibits the reaction [Isoproterenol results in increased cleavage of CASP3 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; benidipine inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Progesterone inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of CASP3 protein]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]
Isoproterenol results in increased expression of CASP3 mRNA; Isoproterenol results in increased expression of CASP3 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]		 CTD PMID:11218852 PMID:17136323 PMID:17961425 PMID:20726854 PMID:21745194 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP6 caspase 6 decreases expression ISO Isoproterenol results in decreased expression of CASP6 mRNA CTD PMID:21335049 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583 		JBrowse link
G CASP7 caspase 7 multiple interactions
decreases expression		 EXP
ISO		 Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of CASP7 mRNA
Isoproterenol results in decreased expression of CASP7 mRNA		 CTD PMID:17136323 PMID:24286936 PMID:30303030 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CASP8 mRNA; Isoproterenol results in increased expression of CASP8 protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP8 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]		 CTD PMID:25794854 PMID:26996544 PMID:30152906 PMID:34816538 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases expression
increases cleavage
increases activity
multiple interactions		 ISO Isoproterenol results in increased expression of CASP9 mRNA; Isoproterenol results in increased expression of CASP9 protein
Isoproterenol results in increased cleavage of CASP9 protein
Isoproterenol results in increased activity of CASP9 protein
anethole inhibits the reaction [Isoproterenol results in increased cleavage of CASP9 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP9 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of CASP9 protein]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]		 CTD PMID:24286936 PMID:25794854 PMID:26996544 PMID:30152906 PMID:32865837 More... NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase decreases expression
multiple interactions
decreases activity
increases activity
increases expression		 ISO Isoproterenol results in decreased expression of CAT protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Rosuvastatin Calcium co-treated with Isoproterenol] inhibits the reaction [Interleukin-6 results in increased expression of CAT protein]; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; anethole inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Apigenin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol promotes the reaction [Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; benidipine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of CAT protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; erdosteine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; ferruginol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of CAT mRNA]; Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; imetit inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; Isoproterenol results in decreased expression of and results in decreased activity of CAT protein; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; punicalagin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]]; pyrvinium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin promotes the reaction [Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]
Isoproterenol results in decreased expression of CAT mRNA; Isoproterenol results in decreased expression of CAT protein
Isoproterenol results in increased expression of CAT mRNA		 CTD PMID:1840475 PMID:12708743 PMID:15740881 PMID:16584858 PMID:16697266 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 multiple interactions ISO CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] CTD PMID:18820136 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CAV3 caveolin 3 affects localization ISO Isoproterenol affects the localization of CAV3 protein CTD PMID:19299911 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808 		JBrowse link
G CBLB Cbl proto-oncogene B increases expression ISO Isoproterenol results in increased expression of CBLB mRNA CTD PMID:20003209 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552 		JBrowse link
G CCDC80 coiled-coil domain containing 80 increases expression ISO Isoproterenol results in increased expression of CCDC80 mRNA CTD PMID:20003209 NCBI chr 3:112,596,797...112,641,143
Ensembl chr 3:112,596,797...112,649,530 		JBrowse link
G CCDC85A coiled-coil domain containing 85A increases expression ISO Isoproterenol results in increased expression of CCDC85A mRNA CTD PMID:20003209 NCBI chr 2:56,183,852...56,386,174
Ensembl chr 2:56,183,990...56,386,172 		JBrowse link
G CCL15 C-C motif chemokine ligand 15 increases expression ISO Isoproterenol results in increased expression of CCL6 mRNA CTD PMID:20003209 NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 decreases secretion EXP Isoproterenol results in decreased secretion of CCL17 protein CTD PMID:12871855 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 increases expression ISO Isoproterenol results in increased expression of CCL2 mRNA CTD PMID:21823215 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL23 C-C motif chemokine ligand 23 increases expression ISO Isoproterenol results in increased expression of CCL9 mRNA CTD PMID:20003209 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions
increases expression
decreases expression		 EXP
ISO		 Isoproterenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]
Isoproterenol results in increased expression of CCL3 protein
Isoproterenol results in decreased expression of CCL3 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]		 CTD PMID:9863660 PMID:12538206 PMID:21335049 PMID:24286936 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL7 C-C motif chemokine ligand 7 decreases expression
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of CCL7 mRNA
Isoproterenol results in increased expression of CCL7 mRNA		 CTD PMID:20211217 PMID:24286936 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242 		JBrowse link
G CCN2 cellular communication network factor 2 increases expression
multiple interactions
decreases expression		 ISO Isoproterenol results in increased expression of CCN2 mRNA
Isoproterenol results in increased expression of CCN2 mRNA; Isoproterenol results in increased expression of CCN2 protein
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]
Isoproterenol results in decreased expression of CCN2 mRNA		 CTD PMID:20003209 PMID:24117263 PMID:24286936 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCND1 cyclin D1 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of CCND1 mRNA
Isoproterenol results in increased expression of CCND1 mRNA		 CTD PMID:20003209 PMID:21335049 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCND3 cyclin D3 increases expression ISO Isoproterenol results in increased expression of CCND3 mRNA CTD PMID:20003209 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357 		JBrowse link
G CCNG2 cyclin G2 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CCNG2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 4:77,157,207...77,170,060
Ensembl chr 4:77,157,207...77,433,388 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 increases expression ISO Isoproterenol results in increased expression of CCR1 mRNA CTD PMID:20211217 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CD14 CD14 molecule increases expression ISO Isoproterenol results in increased expression of CD14 mRNA CTD PMID:20003209 PMID:20211217 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD163 CD163 molecule increases expression ISO Isoproterenol results in increased expression of CD163 mRNA CTD PMID:20003209 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD302 CD302 molecule increases expression ISO Isoproterenol results in increased expression of CD302 mRNA CTD PMID:20003209 NCBI chr 2:159,768,628...159,798,208
Ensembl chr 2:159,768,628...159,798,255 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) decreases expression ISO Isoproterenol results in decreased expression of CD36 protein CTD PMID:19826179 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD38 CD38 molecule multiple interactions ISO Isoproterenol promotes the reaction [CD38 gene mutant form results in increased activity of REN protein] CTD PMID:23343681 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232 		JBrowse link
G CD74 CD74 molecule decreases expression ISO Isoproterenol results in decreased expression of CD74 mRNA CTD PMID:20003209 NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969 		JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of CDC37 mRNA CTD PMID:30303030 NCBI chr19:10,391,133...10,403,542
Ensembl chr19:10,391,133...10,420,121 		JBrowse link
G CDC37L1 cell division cycle 37 like 1, HSP90 cochaperone increases expression ISO Isoproterenol results in increased expression of CDC37L1 mRNA CTD PMID:20003209 NCBI chr 9:4,679,569...4,708,399
Ensembl chr 9:4,679,559...4,708,399 		JBrowse link
G CDC42EP3 CDC42 effector protein 3 decreases expression ISO Isoproterenol results in decreased expression of CDC42EP3 mRNA CTD PMID:20003209 NCBI chr 2:37,641,944...37,672,949
Ensembl chr 2:37,641,882...37,738,468 		JBrowse link
G CDC42EP4 CDC42 effector protein 4 increases expression ISO Isoproterenol results in increased expression of CDC42EP4 mRNA CTD PMID:20003209 NCBI chr17:73,283,624...73,312,001
Ensembl chr17:73,283,624...73,312,005 		JBrowse link
G CDH11 cadherin 11 increases expression ISO Isoproterenol results in increased expression of CDH11 mRNA CTD PMID:20003209 NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112 		JBrowse link
G CDH13 cadherin 13 decreases expression ISO Isoproterenol results in decreased expression of CDH13 mRNA CTD PMID:20003209 NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640 		JBrowse link
G CDH2 cadherin 2 decreases expression ISO Isoproterenol results in decreased expression of CDH2 mRNA CTD PMID:21335049 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDK1 cyclin dependent kinase 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CDK1 mRNA; Isoproterenol results in increased expression of CDK1 protein
Atenolol inhibits the reaction [Isoproterenol results in increased expression of CDK1 mRNA]		 CTD PMID:9593584 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CDKN1A mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CDO1 cysteine dioxygenase type 1 increases expression ISO Isoproterenol results in increased expression of CDO1 mRNA CTD PMID:20003209 NCBI chr 5:115,804,733...115,816,659
Ensembl chr 5:115,804,733...115,816,659 		JBrowse link
G CDS2 CDP-diacylglycerol synthase 2 increases expression ISO Isoproterenol results in increased expression of CDS2 mRNA CTD PMID:20003209 NCBI chr20:5,127,008...5,197,887
Ensembl chr20:5,126,879...5,197,887 		JBrowse link
G CDV3 CDV3 homolog increases expression ISO Isoproterenol results in increased expression of CDV3 mRNA CTD PMID:20003209 NCBI chr 3:133,573,686...133,590,274
Ensembl chr 3:133,573,686...133,590,261 		JBrowse link
G CDYL chromodomain Y like increases expression ISO Isoproterenol results in increased expression of CDYL mRNA CTD PMID:20003209 NCBI chr 6:4,706,138...4,955,544
Ensembl chr 6:4,706,159...4,955,551 		JBrowse link
G CEBPD CCAAT enhancer binding protein delta increases expression ISO Isoproterenol results in increased expression of CEBPD mRNA CTD PMID:20003209 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164 		JBrowse link
G CEBPG CCAAT enhancer binding protein gamma increases expression ISO Isoproterenol results in increased expression of CEBPG mRNA CTD PMID:20003209 NCBI chr19:33,373,709...33,382,686
Ensembl chr19:33,373,685...33,382,686 		JBrowse link
G CENPA centromere protein A decreases expression ISO Isoproterenol results in decreased expression of CENPA mRNA CTD PMID:20003209 NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067 		JBrowse link
G CEP192 centrosomal protein 192 increases expression ISO Isoproterenol results in increased expression of CEP192 mRNA CTD PMID:20003209 NCBI chr18:12,991,362...13,125,036
Ensembl chr18:12,991,362...13,125,052 		JBrowse link
G CFH complement factor H increases expression ISO Isoproterenol results in increased expression of CFH mRNA CTD PMID:20003209 NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476 		JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions
increases activity		 EXP
ISO		 [Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein; Baclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Enkephalin, Leucine-2-Alanine promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Serotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15020588 PMID:15039139 PMID:15151902 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CH25H cholesterol 25-hydroxylase increases expression ISO Isoproterenol results in increased expression of CH25H mRNA CTD PMID:20211217 NCBI chr10:89,205,629...89,207,317
Ensembl chr10:89,205,629...89,207,317 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 increases expression ISO Isoproterenol results in increased expression of CHAC1 mRNA CTD PMID:20003209 NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512 		JBrowse link
G CHKA choline kinase alpha increases expression ISO Isoproterenol results in increased expression of CHKA mRNA CTD PMID:20003209 NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of CHUK mRNA CTD PMID:30303030 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596 		JBrowse link
G CIDEC cell death inducing DFFA like effector c multiple interactions ISO Isoproterenol results in increased expression of and results in decreased degradation of CIDEC protein; KT 5720 inhibits the reaction [Isoproterenol results in increased expression of CIDEC protein] CTD PMID:21097823 NCBI chr 3:9,866,710...9,880,253
Ensembl chr 3:9,866,711...9,880,255 		JBrowse link
G CILP cartilage intermediate layer protein increases expression ISO Isoproterenol results in increased expression of CILP mRNA CTD PMID:20003209 NCBI chr15:65,194,760...65,211,473
Ensembl chr15:65,194,760...65,211,473 		JBrowse link
G CIRBP cold inducible RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of CIRBP mRNA CTD PMID:20003209 NCBI chr19:1,269,332...1,274,880
Ensembl chr19:1,259,384...1,274,880 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 increases expression ISO Isoproterenol results in increased expression of CITED2 mRNA CTD PMID:20003209 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 decreases expression ISO Isoproterenol results in decreased expression of CITED4 mRNA CTD PMID:20003209 NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363 		JBrowse link
G CKB creatine kinase B multiple interactions
increases activity		 ISO benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Lutein inhibits the reaction [Isoproterenol results in increased activity of CKB protein] CTD PMID:19146839 PMID:22391854 PMID:25269373 PMID:25496245 PMID:34435724 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833 		JBrowse link
G CKM creatine kinase, M-type multiple interactions
increases secretion		 ISO [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; aliskiren inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]; Isoproterenol results in increased expression of and results in increased secretion of CKM protein; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of CKM protein] CTD PMID:19146839 PMID:22391854 PMID:25269373 PMID:25496245 PMID:26982530 More... NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875 		JBrowse link
G CLCA1 chloride channel accessory 1 increases expression ISO Isoproterenol results in increased expression of CLCA1 mRNA CTD PMID:20003209 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 decreases expression ISO Isoproterenol results in decreased expression of CLCN3 mRNA CTD PMID:20003209 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673 		JBrowse link
G CLEC1A C-type lectin domain family 1 member A increases expression ISO Isoproterenol results in increased expression of CLEC1A mRNA CTD PMID:20003209 NCBI chr12:10,069,554...10,098,985
Ensembl chr12:10,069,554...10,111,627 		JBrowse link
G CLEC2D C-type lectin domain family 2 member D increases expression ISO Isoproterenol results in increased expression of CLEC2D mRNA CTD PMID:20003209 NCBI chr12:9,669,713...9,699,553
Ensembl chr12:9,664,969...9,699,553 		JBrowse link
G CLEC4D C-type lectin domain family 4 member D increases expression ISO Isoproterenol results in increased expression of CLEC4D mRNA CTD PMID:20003209 NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366 		JBrowse link
G CLEC6A C-type lectin domain containing 6A increases expression ISO Isoproterenol results in increased expression of CLEC4N mRNA CTD PMID:20003209 NCBI chr12:8,455,962...8,478,330
Ensembl chr12:8,455,962...8,478,330 		JBrowse link
G CLIC5 chloride intracellular channel 5 increases expression ISO Isoproterenol results in increased expression of CLIC5 mRNA CTD PMID:20003209 NCBI chr 6:45,880,827...46,129,819
Ensembl chr 6:45,880,827...46,080,348 		JBrowse link
G CLIP1 CAP-Gly domain containing linker protein 1 increases expression ISO Isoproterenol results in increased expression of CLIP1 mRNA CTD PMID:20003209 NCBI chr12:122,271,469...122,422,956
Ensembl chr12:122,271,432...122,422,669 		JBrowse link
G CLIP4 CAP-Gly domain containing linker protein family member 4 decreases expression ISO Isoproterenol results in decreased expression of CLIP4 mRNA CTD PMID:20003209 NCBI chr 2:29,097,726...29,183,808
Ensembl chr 2:29,097,705...29,199,777 		JBrowse link
G CLPB ClpB family mitochondrial disaggregase decreases expression ISO Isoproterenol results in decreased expression of CLPB mRNA CTD PMID:20003209 NCBI chr11:72,285,495...72,434,531
Ensembl chr11:72,285,495...72,434,680 		JBrowse link
G CLU clusterin increases expression ISO Isoproterenol results in increased expression of CLU mRNA; Isoproterenol results in increased expression of CLU protein CTD PMID:15052282 PMID:20003209 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CNKSR1 connector enhancer of kinase suppressor of Ras 1 increases expression ISO Isoproterenol results in increased expression of CNKSR1 mRNA CTD PMID:20003209 NCBI chr 1:26,177,491...26,189,884
Ensembl chr 1:26,177,484...26,189,884 		JBrowse link
G CNKSR3 CNKSR family member 3 increases expression ISO Isoproterenol results in increased expression of CNKSR3 mRNA CTD PMID:20003209 NCBI chr 6:154,387,515...154,510,685
Ensembl chr 6:154,387,515...154,510,685 		JBrowse link
G COBLL1 cordon-bleu WH2 repeat protein like 1 increases expression ISO Isoproterenol results in increased expression of COBLL1 mRNA CTD PMID:20003209 NCBI chr 2:164,657,931...164,842,076
Ensembl chr 2:164,653,624...164,843,679 		JBrowse link
G COL15A1 collagen type XV alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL15A1 mRNA CTD PMID:20003209 NCBI chr 9:98,943,907...99,070,787
Ensembl chr 9:98,943,179...99,070,787 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions
increases expression 		ISO manidipine inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]
isoprenaline increases expression of Col1a1 protein in blood serum
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]
Isoproterenol results in increased expression of COL1A1 mRNA; Isoproterenol results in increased expression of COL1A1 protein		 CTD
RGD		 PMID:9559417 PMID:24945829 PMID:26692091 PMID:28526319 PMID:31009642 More... RGD:156430318 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL2A1 collagen type II alpha 1 chain multiple interactions
decreases expression		 ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]
Isoproterenol results in decreased expression of COL2A1 mRNA; Isoproterenol results in decreased expression of COL2A1 protein		 CTD PMID:21177286 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554 		JBrowse link
G COL3A1 collagen type III alpha 1 chain multiple interactions
increases expression 		ISO AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; manidipine inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]
isoprenaline increases expression of Col3a1 protein in blood serum
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]
Isoproterenol results in increased expression of COL3A1 mRNA; Isoproterenol results in increased expression of COL3A1 protein		 CTD
RGD		 PMID:9559417 PMID:20409916 PMID:26692091 PMID:31009642 PMID:31712309 More... RGD:156430318 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL5A1 collagen type V alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL5A1 mRNA CTD PMID:21335049 NCBI chr 9:134,641,803...134,844,843
Ensembl chr 9:134,641,803...134,844,843 		JBrowse link
G COL5A2 collagen type V alpha 2 chain increases expression ISO Isoproterenol results in increased expression of COL5A2 mRNA CTD PMID:20003209 NCBI chr 2:189,031,898...189,441,111
Ensembl chr 2:189,031,898...189,225,312 		JBrowse link
G COMT catechol-O-methyltransferase increases methylation EXP COMT protein results in increased methylation of Isoproterenol CTD PMID:11160877 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G COPS3 COP9 signalosome subunit 3 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of COPS3 mRNA CTD PMID:30303030 NCBI chr17:17,246,616...17,281,246
Ensembl chr17:17,246,616...17,281,273 		JBrowse link
G CORIN corin, serine peptidase increases expression ISO Isoproterenol results in increased expression of CORIN mRNA CTD PMID:20003209 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106 		JBrowse link
G CP ceruloplasmin multiple interactions
increases expression
decreases activity		 ISO allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of CP protein]
Isoproterenol results in increased expression of CP protein
Isoproterenol results in increased expression of CP mRNA		 CTD PMID:1521861 PMID:15261977 PMID:20003209 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CPNE8 copine 8 increases expression ISO Isoproterenol results in increased expression of CPNE8 mRNA CTD PMID:20003209 NCBI chr12:38,652,203...38,906,835
Ensembl chr12:38,646,822...38,907,430 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 increases expression ISO Isoproterenol results in increased expression of CPS1 mRNA CTD PMID:21335049 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT1A mRNA CTD PMID:30303030 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CPT1B carnitine palmitoyltransferase 1B multiple interactions
decreases expression		 ISO Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]] CTD PMID:25045214 NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465 		JBrowse link
G CPT2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of CPT2 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT2 mRNA; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]]		 CTD PMID:25045214 PMID:30303030 NCBI chr 1:53,196,824...53,214,197
Ensembl chr 1:53,196,792...53,214,197 		JBrowse link
G CRB1 crumbs cell polarity complex component 1 increases expression ISO Isoproterenol results in increased expression of CRB1 mRNA CTD PMID:20003209 NCBI chr 1:197,201,504...197,478,455
Ensembl chr 1:197,268,204...197,478,455 		JBrowse link
G CRBN cereblon increases expression ISO Isoproterenol results in increased expression of CRBN mRNA CTD PMID:20003209 NCBI chr 3:3,149,633...3,179,717
Ensembl chr 3:3,144,628...3,179,727 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO oxophenylarsine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]
CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]		 CTD PMID:12791704 PMID:17141199 PMID:21745194 PMID:32686902 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREM cAMP responsive element modulator multiple interactions
increases expression
affects localization		 ISO CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]
Isoproterenol results in increased expression of CREM mRNA; Isoproterenol results in increased expression of CREM protein
Isoproterenol affects the localization of CREM protein		 CTD PMID:12791704 PMID:20211217 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CRLF1 cytokine receptor like factor 1 increases expression ISO Isoproterenol results in increased expression of CRLF1 mRNA CTD PMID:20003209 NCBI chr19:18,593,237...18,606,799
Ensembl chr19:18,572,220...18,607,741 		JBrowse link
G CRP C-reactive protein increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CRP protein
benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CRP protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of CRP protein]; Isoproterenol results in increased expression of and results in increased secretion of CRP protein		 CTD PMID:25269373 PMID:35608392 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CRYAB crystallin alpha B multiple interactions ISO Isoproterenol inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CRYBA4 crystallin beta A4 decreases expression ISO Isoproterenol results in decreased expression of CRYBA4 mRNA CTD PMID:20003209 NCBI chr22:26,590,220...26,630,669
Ensembl chr22:26,621,963...26,630,669 		JBrowse link
G CS citrate synthase decreases activity ISO Isoproterenol results in decreased activity of CS protein CTD PMID:27491814 NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391 		JBrowse link
G CSDC2 cold shock domain containing C2 increases expression ISO Isoproterenol results in increased expression of CSDC2 mRNA CTD PMID:20003209 NCBI chr22:41,561,010...41,576,666
Ensembl chr22:41,561,010...41,577,741 		JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta increases expression ISO Isoproterenol results in increased expression of CSF2RB mRNA; Isoproterenol results in increased expression of CSF2RB2 mRNA CTD PMID:20003209 NCBI chr22:36,913,628...36,940,439
Ensembl chr22:36,913,628...36,940,439 		JBrowse link
G CSK C-terminal Src kinase multiple interactions ISO CSK protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197 		JBrowse link
G CTF1 cardiotrophin 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CTF1 mRNA; Isoproterenol results in increased expression of CTF1 protein
Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]; valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]		 CTD PMID:23288202 NCBI chr16:30,895,846...30,903,560
Ensembl chr16:30,896,614...30,903,547 		JBrowse link
G CTH cystathionine gamma-lyase multiple interactions ISO [Isoproterenol co-treated with Caffeine] results in decreased expression of CTH mRNA CTD PMID:29447158 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851 		JBrowse link
G CTHRC1 collagen triple helix repeat containing 1 increases expression ISO Isoproterenol results in increased expression of CTHRC1 mRNA CTD PMID:20003209 NCBI chr 8:103,371,538...103,382,989
Ensembl chr 8:103,371,538...103,382,989 		JBrowse link
G CTNNAL1 catenin alpha like 1 increases expression ISO Isoproterenol results in increased expression of CTNNAL1 mRNA CTD PMID:20003209 NCBI chr 9:108,942,577...109,013,499
Ensembl chr 9:108,942,569...109,013,522 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions
increases expression		 ISO [Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA; Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]; pyrvinium inhibits the reaction [[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of CTNNB1 protein]
Isoproterenol results in increased expression of CTNNB1 mRNA; Isoproterenol results in increased expression of CTNNB1 protein		 CTD PMID:35305975 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CTNNBIP1 catenin beta interacting protein 1 decreases expression ISO Isoproterenol results in decreased expression of CTNNBIP1 mRNA CTD PMID:20003209 NCBI chr 1:9,848,276...9,910,269
Ensembl chr 1:9,848,276...9,910,336 		JBrowse link
G CTPS2 CTP synthase 2 increases expression ISO Isoproterenol results in increased expression of CTPS2 mRNA CTD PMID:20003209 NCBI chr  X:16,587,999...16,712,910
Ensembl chr  X:16,587,999...16,712,936 		JBrowse link
G CTSB cathepsin B multiple interactions
increases activity
decreases expression
decreases activity		 ISO caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]
Isoproterenol results in decreased expression of CTSB mRNA		 CTD PMID:2015110 PMID:8534267 PMID:17188415 PMID:18294627 PMID:20391626 More... NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSD cathepsin D multiple interactions
affects activity
increases activity
decreases activity
increases expression		 ISO [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; alliin affects the reaction [Isoproterenol affects the activity of CTSD protein]; caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]
Isoproterenol results in increased expression of CTSD mRNA; Isoproterenol results in increased expression of CTSD protein		 CTD PMID:894732 PMID:2015110 PMID:8534267 PMID:11829124 PMID:14499179 More... NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CTSL cathepsin L increases expression ISO Isoproterenol results in increased expression of CTSL mRNA CTD PMID:20003209 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CUL1 cullin 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of CUL1 mRNA CTD PMID:30303030 NCBI chr 7:148,697,756...148,801,110
Ensembl chr 7:148,697,914...148,801,110 		JBrowse link
G CUL4B cullin 4B increases expression ISO Isoproterenol results in increased expression of CUL4B mRNA CTD PMID:20003209 NCBI chr  X:120,523,858...120,575,532
Ensembl chr  X:120,505,920...120,604,074 		JBrowse link
G CUX2 cut like homeobox 2 decreases expression ISO Isoproterenol results in decreased expression of CUX2 mRNA CTD PMID:20003209 NCBI chr12:111,034,165...111,350,554
Ensembl chr12:111,034,165...111,350,554 		JBrowse link
G CUZD1 CUB and zona pellucida like domains 1 increases expression ISO Isoproterenol results in increased expression of CUZD1 mRNA CTD PMID:20003209 NCBI chr10:122,832,158...122,845,857
Ensembl chr10:122,832,158...122,846,175 		JBrowse link
G CXCL13 C-X-C motif chemokine ligand 13 increases expression ISO Isoproterenol results in increased expression of CXCL13 mRNA CTD PMID:20003209 NCBI chr 4:77,511,753...77,611,834
Ensembl chr 4:77,511,753...77,611,834 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression		 EXP Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]
Isoproterenol results in increased expression of CXCL8 mRNA		 CTD PMID:9258252 PMID:21088047 PMID:32816093 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 decreases expression ISO Isoproterenol results in decreased expression of CXCL9 mRNA CTD PMID:20003209 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 increases activity ISO Isoproterenol results in increased activity of CXCR2 protein CTD PMID:15477226 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G CXXC5 CXXC finger protein 5 decreases expression ISO Isoproterenol results in decreased expression of CXXC5 mRNA CTD PMID:20003209 NCBI chr 5:139,647,299...139,683,882
Ensembl chr 5:139,647,299...139,683,882 		JBrowse link
G CYBA cytochrome b-245 alpha chain increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CYBA mRNA
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]		 CTD PMID:18594475 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYCS cytochrome c, somatic increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of CYCS protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CYCS protein]		 CTD PMID:30152906 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in decreased expression of CYP1A1 mRNA
Isoproterenol results in increased expression of CYP1A1 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]		 CTD PMID:15627480 PMID:15710352 PMID:18725507 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions EXP
ISO		 Isoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]		 CTD PMID:15710352 PMID:18493746 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression ISO Isoproterenol results in increased expression of CYP1B1 mRNA CTD PMID:18725507 PMID:20003209 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 decreases expression ISO Isoproterenol results in decreased expression of CYP26B1 mRNA CTD PMID:20003209 NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 increases activity ISO Isoproterenol results in increased activity of CYP2A5 protein CTD PMID:11162586 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases expression ISO Isoproterenol results in increased expression of CYP2B10 mRNA CTD PMID:20003209 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 decreases expression ISO Isoproterenol results in decreased expression of CYP2C11 mRNA CTD PMID:18725507 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 affects expression ISO Isoproterenol affects the expression of CYP2E1 mRNA CTD PMID:18725507 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 increases expression ISO Isoproterenol results in increased expression of CYSLTR1 mRNA CTD PMID:20003209 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G DAG1 dystroglycan 1 decreases expression ISO Isoproterenol results in decreased expression of DAG1 CTD PMID:18808529 NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618 		JBrowse link
G DAP death associated protein multiple interactions
increases expression		 ISO [Isoproterenol co-treated with POSTN protein] results in increased expression of DAP mRNA
Isoproterenol results in increased expression of DAP mRNA		 CTD PMID:30303030 NCBI chr 5:10,679,230...10,761,234
Ensembl chr 5:10,679,230...10,761,234 		JBrowse link
G DBP D-box binding PAR bZIP transcription factor decreases expression ISO Isoproterenol results in decreased expression of DBP mRNA CTD PMID:20003209 NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379 		JBrowse link
G DCAKD dephospho-CoA kinase domain containing decreases expression ISO Isoproterenol results in decreased expression of DCAKD mRNA CTD PMID:20003209 NCBI chr17:45,023,338...45,061,131
Ensembl chr17:45,023,338...45,061,131 		JBrowse link
G DCN decorin increases expression ISO Isoproterenol results in increased expression of DCN mRNA CTD PMID:20003209 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217 		JBrowse link
G DCT dopachrome tautomerase increases expression ISO Isoproterenol results in increased expression of DCT mRNA CTD PMID:20003209 NCBI chr13:94,436,811...94,549,406
Ensembl chr13:94,436,811...94,479,682 		JBrowse link
G DCTN5 dynactin subunit 5 increases expression ISO Isoproterenol results in increased expression of DCTN5 mRNA CTD PMID:21335049 NCBI chr16:23,641,466...23,677,472
Ensembl chr16:23,641,466...23,677,472 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of DDIT3 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]]		 CTD PMID:21823215 PMID:29414845 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of DDIT4 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression ISO Isoproterenol results in increased expression of DDOST mRNA CTD PMID:21823215 NCBI chr 1:20,651,777...20,661,369
Ensembl chr 1:20,651,767...20,661,544 		JBrowse link
G DEFB1 defensin beta 1 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of DEFB1 mRNA
Isoproterenol results in increased expression of DEFB1 mRNA		 CTD PMID:24286936 NCBI chr 8:6,870,592...6,877,936
Ensembl chr 8:6,870,592...6,877,936 		JBrowse link
G DENND4A DENN domain containing 4A increases expression ISO Isoproterenol results in increased expression of DENND4A mRNA CTD PMID:20003209 NCBI chr15:65,659,123...65,792,293
Ensembl chr15:65,658,046...65,792,293 		JBrowse link
G DERL2 derlin 2 increases expression ISO Isoproterenol results in increased expression of DERL2 mRNA CTD PMID:21823215 NCBI chr17:5,471,254...5,486,817
Ensembl chr17:5,471,254...5,486,811 		JBrowse link
G DERL3 derlin 3 decreases expression ISO Isoproterenol results in decreased expression of DERL3 mRNA CTD PMID:21823215 NCBI chr22:23,834,503...23,839,006
Ensembl chr22:23,834,503...23,839,128 		JBrowse link
G DES desmin multiple interactions
decreases expression		 ISO Lutein inhibits the reaction [Isoproterenol results in decreased expression of DES protein] CTD PMID:34435724 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735 		JBrowse link
G DFFB DNA fragmentation factor subunit beta increases expression ISO Isoproterenol results in increased expression of DFFB mRNA CTD PMID:20003209 NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase decreases expression ISO Isoproterenol results in decreased expression of DHCR24 mRNA CTD PMID:20003209 NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195 		JBrowse link
G DHRS3 dehydrogenase/reductase 3 decreases expression ISO Isoproterenol results in decreased expression of DHRS3 mRNA CTD PMID:21335049 NCBI chr 1:12,567,910...12,618,210
Ensembl chr 1:12,567,910...12,618,210 		JBrowse link
G DHRS7 dehydrogenase/reductase 7 decreases expression ISO Isoproterenol results in decreased expression of DHRS7 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr14:60,144,119...60,169,889
Ensembl chr14:60,144,119...60,169,856 		JBrowse link
G DHRS7C dehydrogenase/reductase 7C decreases expression ISO Isoproterenol results in decreased expression of DHRS7C mRNA CTD PMID:20003209 NCBI chr17:9,771,438...9,791,592
Ensembl chr17:9,771,434...9,791,592 		JBrowse link
G DIAPH2 diaphanous related formin 2 increases expression ISO Isoproterenol results in increased expression of DIAPH2 mRNA CTD PMID:20003209 NCBI chr  X:96,684,842...97,604,997
Ensembl chr  X:96,684,712...97,604,997 		JBrowse link
G DIO2 iodothyronine deiodinase 2 increases expression
increases activity		 ISO Isoproterenol results in increased expression of DIO2 mRNA
Isoproterenol results in increased activity of DIO2 protein		 CTD PMID:15345674 PMID:20003209 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DIXDC1 DIX domain containing 1 increases expression ISO Isoproterenol results in increased expression of DIXDC1 mRNA CTD PMID:20003209 NCBI chr11:111,927,315...112,022,653
Ensembl chr11:111,927,144...112,022,653 		JBrowse link
G DLAT dihydrolipoamide S-acetyltransferase decreases expression ISO Isoproterenol results in decreased expression of DLAT mRNA CTD PMID:21335049 NCBI chr11:112,025,408...112,064,404
Ensembl chr11:112,025,033...112,064,404 		JBrowse link
G DMAC2L distal membrane arm assembly component 2 like multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of DMAC2L mRNA CTD PMID:30303030 NCBI chr14:50,311,516...50,327,957
Ensembl chr14:50,312,324...50,335,558 		JBrowse link
G DMD dystrophin multiple interactions
decreases expression		 ISO DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of DMD		 CTD PMID:18340010 PMID:18808529 NCBI chr  X:31,119,222...33,339,388
Ensembl chr  X:31,097,677...33,339,609 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Isoproterenol results in increased expression of DNAJB11 mRNA CTD PMID:21823215 NCBI chr 3:186,570,720...186,585,793
Ensembl chr 3:186,567,403...186,585,800 		JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Isoproterenol results in increased expression of DNAJB9 mRNA CTD PMID:21335049 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850 		JBrowse link
G DNM1L dynamin 1 like increases phosphorylation ISO Isoproterenol results in increased phosphorylation of DNM1L protein CTD PMID:27491814 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of DNMT3A mRNA
Isoproterenol results in increased expression of DNMT3A protein		 CTD PMID:20003209 PMID:24945829 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta increases expression ISO Isoproterenol results in increased expression of DNMT3B mRNA CTD PMID:21335049 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 increases expression ISO Isoproterenol results in increased expression of DNTTIP2 mRNA CTD PMID:20003209 NCBI chr 1:93,866,284...93,879,206
Ensembl chr 1:93,866,284...93,879,918 		JBrowse link
G DOC2GP double C2 domain gamma, pseudogene decreases expression ISO Isoproterenol results in decreased expression of DOC2G mRNA CTD PMID:20003209 NCBI chr11:67,613,524...67,615,664
Ensembl chr11:67,612,837...67,616,257 		JBrowse link
G DOCK10 dedicator of cytokinesis 10 increases expression ISO Isoproterenol results in increased expression of DOCK10 mRNA CTD PMID:20003209 NCBI chr 2:224,765,090...225,042,468
Ensembl chr 2:224,765,090...225,042,468 		JBrowse link
G DOCK9 dedicator of cytokinesis 9 increases expression ISO Isoproterenol results in increased expression of DOCK9 mRNA CTD PMID:20003209 NCBI chr13:98,793,429...99,088,619
Ensembl chr13:98,793,429...99,086,625 		JBrowse link
G DPEP1 dipeptidase 1 increases expression ISO Isoproterenol results in increased expression of DPEP1 mRNA CTD PMID:20003209 NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456 		JBrowse link
G DPP7 dipeptidyl peptidase 7 increases expression ISO Isoproterenol results in increased expression of DPP7 mRNA CTD PMID:20003209 NCBI chr 9:137,110,546...137,118,306
Ensembl chr 9:137,110,542...137,118,309 		JBrowse link
G DSG2 desmoglein 2 decreases expression ISO Isoproterenol results in decreased expression of DSG2 mRNA CTD PMID:20003209 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008 		JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 increases expression ISO Isoproterenol results in increased expression of DTX4 mRNA CTD PMID:20003209 NCBI chr11:59,171,430...59,208,588
Ensembl chr11:59,171,430...59,208,588 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein] CTD PMID:21177286 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP4 dual specificity phosphatase 4 increases expression ISO Isoproterenol results in increased expression of DUSP4 mRNA CTD PMID:20003209 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684 		JBrowse link
G DUSP5 dual specificity phosphatase 5 decreases expression ISO isoprenaline decreases expression of Dusp5 mRNA and protein in cardiac muscle cells RGD PMID:27318893 RGD:156430318 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DUSP8 dual specificity phosphatase 8 decreases expression ISO Isoproterenol results in decreased expression of DUSP8 mRNA CTD PMID:20003209 NCBI chr11:1,554,051...1,572,848
Ensembl chr11:1,554,051...1,572,271 		JBrowse link
G DXO decapping exoribonuclease increases expression ISO Isoproterenol results in increased expression of DXO mRNA CTD PMID:21335049 NCBI chr 6:31,969,815...31,972,138
Ensembl chr 6:31,969,810...31,972,290 		JBrowse link
G ECM1 extracellular matrix protein 1 increases expression ISO Isoproterenol results in increased expression of ECM1 mRNA CTD PMID:20003209 NCBI chr 1:150,508,109...150,513,789
Ensembl chr 1:150,508,062...150,513,789 		JBrowse link
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Isoproterenol results in increased expression of EDEM1 mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 3:5,187,707...5,219,958
Ensembl chr 3:5,187,646...5,219,958 		JBrowse link
G EDN1 endothelin 1 multiple interactions
increases activity
increases expression		 ISO Cyclosporine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; Nifedipine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]
Isoproterenol results in increased expression of EDN1 mRNA; Isoproterenol results in increased expression of EDN1 protein		 CTD PMID:9861301 PMID:11435416 PMID:27174236 PMID:27890915 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of EDNRA mRNA
Isoproterenol results in increased expression of EDNRA mRNA; Isoproterenol results in increased expression of EDNRA protein
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]		 CTD PMID:18594475 PMID:20003209 PMID:20307649 PMID:27174236 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B multiple interactions
increases expression		 ISO CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRB protein]
Isoproterenol results in increased expression of EDNRB mRNA; Isoproterenol results in increased expression of EDNRB protein		 CTD PMID:18594475 PMID:27174236 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EEF1AKMT1 EEF1A lysine methyltransferase 1 decreases expression ISO Isoproterenol results in decreased expression of EEF1AKMT1 mRNA CTD PMID:20003209 NCBI chr13:20,728,731...20,773,961
Ensembl chr13:20,728,731...20,773,961 		JBrowse link
G EFHD2 EF-hand domain family member D2 increases expression ISO Isoproterenol results in increased expression of EFHD2 mRNA CTD PMID:20003209 NCBI chr 1:15,409,888...15,430,339
Ensembl chr 1:15,409,888...15,430,339 		JBrowse link
G EGFR epidermal growth factor receptor increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of EGFR mRNA
Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]		 CTD PMID:18787115 PMID:20003209 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 multiple interactions
increases expression
decreases expression		 ISO EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA]
Isoproterenol results in increased expression of EGR1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]
Isoproterenol results in decreased expression of EGR1 mRNA		 CTD PMID:10710348 PMID:15621046 PMID:20003209 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Isoproterenol results in increased expression of EIF2AK3 mRNA CTD PMID:21335049 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF4A2 eukaryotic translation initiation factor 4A2 decreases expression ISO Isoproterenol results in decreased expression of EIF4A2 mRNA CTD PMID:21335049 NCBI chr 3:186,783,577...186,789,897
Ensembl chr 3:186,783,205...186,789,897 		JBrowse link
G EIF4E eukaryotic translation initiation factor 4E decreases expression ISO Isoproterenol results in decreased expression of EIF4E mRNA CTD PMID:20003209 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133 		JBrowse link
G ELL2 elongation factor for RNA polymerase II 2 increases expression ISO Isoproterenol results in increased expression of ELL2 mRNA CTD PMID:20003209 NCBI chr 5:95,885,098...95,961,851
Ensembl chr 5:95,885,098...95,961,851 		JBrowse link
G ELN elastin multiple interactions
increases expression		 ISO [Isoproterenol co-treated with Hydralazine] results in increased expression of ELN protein
Isoproterenol results in increased expression of ELN protein		 CTD PMID:3446201 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 increases expression ISO Isoproterenol results in increased expression of ELOVL1 mRNA CTD PMID:20003209 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074 		JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ELP1 mRNA CTD PMID:30303030 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328 		JBrowse link
G ENC1 ectodermal-neural cortex 1 increases expression ISO Isoproterenol results in increased expression of ENC1 mRNA CTD PMID:20003209 NCBI chr 5:74,627,409...74,640,728
Ensembl chr 5:74,627,406...74,641,424 		JBrowse link
G ENO1 enolase 1 decreases expression ISO Isoproterenol results in decreased expression of ENO1 mRNA CTD PMID:20003209 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression ISO Isoproterenol results in decreased expression of ENPP1 protein CTD PMID:21414308 NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Isoproterenol results in increased expression of ENTPD1 mRNA CTD PMID:20003209 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G EPS8 EGFR pathway substrate 8, signaling adaptor increases expression ISO Isoproterenol results in increased expression of EPS8 mRNA CTD PMID:20003209 NCBI chr12:15,620,134...15,789,388
Ensembl chr12:15,620,134...15,882,329 		JBrowse link
G EREG epiregulin increases expression EXP Isoproterenol results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 4:74,365,145...74,388,749
Ensembl chr 4:74,365,145...74,388,749 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 increases expression ISO Isoproterenol results in increased expression of ERP29 mRNA CTD PMID:21335049 NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 increases expression ISO Isoproterenol results in increased expression of ERRFI1 mRNA CTD PMID:20003209 NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309 		JBrowse link
G ETF1 eukaryotic translation termination factor 1 increases expression ISO Isoproterenol results in increased expression of ETF1 mRNA CTD PMID:20003209 NCBI chr 5:138,506,095...138,543,236
Ensembl chr 5:138,506,095...138,543,236 		JBrowse link
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Isoproterenol results in increased expression of EZH1 mRNA CTD PMID:20003209 NCBI chr17:42,700,275...42,745,040
Ensembl chr17:42,700,275...42,745,049 		JBrowse link
G F13A1 coagulation factor XIII A chain increases expression ISO Isoproterenol results in increased expression of F13A1 mRNA CTD PMID:20003209 NCBI chr 6:6,144,084...6,320,662
Ensembl chr 6:6,144,084...6,321,013 		JBrowse link
G FABP3 fatty acid binding protein 3 increases expression
decreases expression		 ISO Isoproterenol results in increased expression of FABP3 protein
Isoproterenol results in decreased expression of FABP3 protein		 CTD PMID:19549929 PMID:19826179 PMID:19854236 PMID:22878004 NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850 		JBrowse link
G FABP5 fatty acid binding protein 5 increases expression ISO Isoproterenol results in increased expression of FABP5 mRNA CTD PMID:21335049 NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777 		JBrowse link
G FAM110D family with sequence similarity 110 member D increases expression ISO Isoproterenol results in increased expression of FAM110D mRNA CTD PMID:20003209 NCBI chr 1:26,159,079...26,163,962
Ensembl chr 1:26,159,079...26,163,962 		JBrowse link
G FAM117B family with sequence similarity 117 member B increases expression ISO Isoproterenol results in increased expression of FAM117B mRNA CTD PMID:20003209 NCBI chr 2:202,634,969...202,769,757
Ensembl chr 2:202,634,969...202,769,757 		JBrowse link
G FARP1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases expression ISO Isoproterenol results in increased expression of FARP1 mRNA CTD PMID:21335049 NCBI chr13:98,142,589...98,455,176
Ensembl chr13:98,142,562...98,455,176 		JBrowse link
G FAS Fas cell surface death receptor increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of FAS mRNA
Apigenin inhibits the reaction [Isoproterenol results in increased expression of FAS protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Thymol inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]
Isoproterenol results in increased expression of FAS mRNA; Isoproterenol results in increased expression of FAS protein		 CTD PMID:11218852 PMID:20003209 PMID:24286936 PMID:25794854 PMID:26996544 More... NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand increases expression ISO Isoproterenol results in increased expression of FASLG protein CTD PMID:19001025 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FBLIM1 filamin binding LIM protein 1 decreases expression ISO Isoproterenol results in decreased expression of FBLIM1 mRNA CTD PMID:20003209 NCBI chr 1:15,756,638...15,786,589
Ensembl chr 1:15,756,607...15,786,594 		JBrowse link
G FBLN2 fibulin 2 increases expression ISO Isoproterenol results in increased expression of FBLN2 mRNA CTD PMID:20003209 NCBI chr 3:13,549,125...13,638,404
Ensembl chr 3:13,549,125...13,638,422 		JBrowse link
G FBXL20 F-box and leucine rich repeat protein 20 increases expression ISO Isoproterenol results in increased expression of FBXL20 mRNA CTD PMID:20003209 NCBI chr17:39,252,663...39,402,556
Ensembl chr17:39,252,663...39,402,523 		JBrowse link
G FBXO31 F-box protein 31 increases expression ISO Isoproterenol results in increased expression of FBXO31 mRNA CTD PMID:20003209 NCBI chr16:87,326,987...87,392,121
Ensembl chr16:87,326,987...87,392,142 		JBrowse link
G FBXO32 F-box protein 32 increases expression ISO Isoproterenol results in increased expression of FBXO32 mRNA CTD PMID:20003209 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206 		JBrowse link
G FBXO9 F-box protein 9 decreases expression ISO Isoproterenol results in decreased expression of FBXO9 mRNA CTD PMID:21335049 NCBI chr 6:53,064,998...53,100,873
Ensembl chr 6:53,051,991...53,100,873 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 decreases expression ISO Isoproterenol results in decreased expression of FBXW7 mRNA CTD PMID:20003209 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092 		JBrowse link
G FCGR2B Fc gamma receptor IIb increases expression ISO Isoproterenol results in increased expression of FCGR2B mRNA CTD PMID:20003209 PMID:20211217 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FCGR3A Fc gamma receptor IIIa increases expression ISO Isoproterenol results in increased expression of FCGR4 mRNA CTD PMID:20003209 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968 		JBrowse link
G FEN1 flap structure-specific endonuclease 1 increases expression ISO Isoproterenol results in increased expression of FEN1 mRNA CTD PMID:21335049 NCBI chr11:61,792,911...61,797,238
Ensembl chr11:61,792,911...61,797,238 		JBrowse link
G FETUB fetuin B increases expression ISO Isoproterenol results in increased expression of FETUB mRNA CTD PMID:20003209 NCBI chr 3:186,635,969...186,653,141
Ensembl chr 3:186,635,969...186,653,141 		JBrowse link
G FGF16 fibroblast growth factor 16 decreases expression ISO Isoproterenol results in decreased expression of FGF16 mRNA CTD PMID:20003209 NCBI chr  X:77,447,389...77,457,278
Ensembl chr  X:77,447,389...77,457,278 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 increases expression ISO Isoproterenol results in increased expression of FGFR3 mRNA CTD PMID:20003209 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FHL1 four and a half LIM domains 1 decreases expression
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of FHL1 mRNA
Isoproterenol results in increased expression of FHL1 mRNA		 CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr  X:136,146,702...136,211,359
Ensembl chr  X:136,146,702...136,211,359 		JBrowse link
G FIS1 fission, mitochondrial 1 increases expression ISO Isoproterenol results in increased expression of FIS1 protein CTD PMID:27491814 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B multiple interactions
decreases expression		 ISO 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]
Isoproterenol results in decreased expression of FKBP1B mRNA; Isoproterenol results in decreased expression of FKBP1B protein		 CTD PMID:20723002 NCBI chr 2:24,033,206...24,063,681
Ensembl chr 2:24,049,701...24,063,681 		JBrowse link
G FKBP4 FKBP prolyl isomerase 4 decreases expression ISO Isoproterenol results in decreased expression of FKBP4 mRNA CTD PMID:20003209 NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 increases expression ISO Isoproterenol results in increased expression of FKBP5 mRNA CTD PMID:20003209 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 increases expression ISO Isoproterenol results in increased expression of FLT1 mRNA CTD PMID:20003209 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 increases expression ISO Isoproterenol results in increased expression of FMO1 mRNA CTD PMID:20003209 NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978 		JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Isoproterenol results in increased expression of FMO2 mRNA CTD PMID:20003209 NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686 		JBrowse link
G FN1 fibronectin 1 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in decreased expression of FN1 protein
Isoproterenol results in increased expression of FN1 protein
Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]
Isoproterenol results in increased expression of FN1 mRNA		 CTD PMID:11821714 PMID:20003209 PMID:24117263 PMID:35305975 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of FOS mRNA; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]
Isoproterenol results in increased expression of FOS mRNA; Isoproterenol results in increased expression of FOS protein
Isoproterenol results in increased expression of FOS; Isoproterenol results in increased expression of FOS mRNA
CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of FOS]		 CTD PMID:7544033 PMID:7905536 PMID:10710348 PMID:12791704 PMID:14764439 More... NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Isoproterenol results in increased expression of FOSB CTD PMID:7905536 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of FOSL1 mRNA
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]
Isoproterenol results in increased expression of FOSL1 mRNA; Isoproterenol results in increased expression of FOSL1 protein		 CTD PMID:20211217 PMID:21177286 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of FOSL2 mRNA; Isoproterenol results in increased expression of FOSL2 protein
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]		 CTD PMID:21177286 NCBI chr 2:28,392,858...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G FOXO1 forkhead box O1 increases phosphorylation ISO Isoproterenol results in increased phosphorylation of FOXO1 protein CTD PMID:15618457 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G FOXO3 forkhead box O3 increases expression ISO Isoproterenol results in increased expression of FOXO3 mRNA CTD PMID:20003209 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774 		JBrowse link
G FRY FRY microtubule binding protein increases expression ISO Isoproterenol results in increased expression of FRY mRNA CTD PMID:20003209 NCBI chr13:32,031,774...32,299,125
Ensembl chr13:31,846,713...32,299,125 		JBrowse link
G FSHB follicle stimulating hormone subunit beta multiple interactions
increases expression		 ISO CPU0213 inhibits the reaction [Isoproterenol results in increased expression of FSHB protein] CTD PMID:20307649 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261 		JBrowse link
G FTL ferritin light chain increases expression ISO Isoproterenol results in increased expression of FTL1 mRNA CTD PMID:20003209 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879 		JBrowse link
G FUS FUS RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of FUS mRNA CTD PMID:20003209 NCBI chr16:31,180,110...31,194,871
Ensembl chr16:31,180,138...31,191,605 		JBrowse link
G G3BP2 G3BP stress granule assembly factor 2 multiple interactions
increases expression		 ISO G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB protein]; Isoproterenol promotes the reaction [G3BP2 protein binds to NFKBIA protein]
Isoproterenol results in increased expression of G3BP2 mRNA; Isoproterenol results in increased expression of G3BP2 protein		 CTD PMID:28816235 NCBI chr 4:75,642,786...75,724,437
Ensembl chr 4:75,641,849...75,724,589 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase multiple interactions
increases activity		 ISO Atenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Gallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GABARAPL1 GABA type A receptor associated protein like 1 increases expression ISO Isoproterenol results in increased expression of GABARAPL1 mRNA CTD PMID:20003209 NCBI chr12:10,212,877...10,223,128
Ensembl chr12:10,212,458...10,223,128 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma increases expression ISO Isoproterenol results in increased expression of GADD45G mRNA CTD PMID:21823215 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555 		JBrowse link
G GAL galanin and GMAP prepropeptide multiple interactions
increases activity
increases expression
decreases activity		 ISO [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GAL mRNA] CTD PMID:2015110 PMID:11829124 PMID:14499179 PMID:17045618 PMID:17182065 More... NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175 		JBrowse link
G GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 increases expression ISO Isoproterenol results in increased expression of GALNT15 mRNA CTD PMID:20003209 NCBI chr 3:16,174,680...16,248,224
Ensembl chr 3:16,174,680...16,231,992 		JBrowse link
G GAS5 growth arrest specific 5 increases expression
decreases expression		 ISO Isoproterenol results in increased expression of GAS5 mRNA
Isoproterenol results in decreased expression of GAS5 mRNA		 CTD PMID:20003209 PMID:28526319 NCBI chr 1:173,863,901...173,869,045
Ensembl chr 1:173,858,559...173,868,882 		JBrowse link
G GAS6 growth arrest specific 6 multiple interactions
decreases expression		 ISO natakalim inhibits the reaction [Isoproterenol results in decreased expression of GAS6 protein] CTD PMID:27890915 NCBI chr13:113,820,549...113,864,076
Ensembl chr13:113,820,549...113,864,076 		JBrowse link
G GATA4 GATA binding protein 4 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNA
Isoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]		 CTD PMID:10710348 PMID:11435416 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002 		JBrowse link
G GBP6 guanylate binding protein family member 6 increases expression ISO Isoproterenol results in increased expression of GBP6 mRNA CTD PMID:20003209 NCBI chr 1:89,364,059...89,388,160
Ensembl chr 1:89,364,059...89,388,160 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases expression ISO Isoproterenol results in decreased expression of GCLC mRNA CTD PMID:21335049 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
multiple interactions
decreases expression		 ISO Isoproterenol results in increased expression of GCLM mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA
Isoproterenol results in decreased expression of GCLM mRNA		 CTD PMID:20003209 PMID:21335049 PMID:30303030 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456 		JBrowse link
G GCNT2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Isoproterenol results in increased expression of GCNT2 mRNA CTD PMID:20003209 NCBI chr 6:10,521,351...10,629,368
Ensembl chr 6:10,492,223...10,629,368 		JBrowse link
G GDA guanine deaminase increases expression ISO Isoproterenol results in increased expression of GDA mRNA CTD PMID:20003209 NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193 		JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of GEM mRNA
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of GEM mRNA]		 CTD PMID:18089841 NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350 		JBrowse link
G GFPT2 glutamine-fructose-6-phosphate transaminase 2 increases expression ISO Isoproterenol results in increased expression of GFPT2 mRNA CTD PMID:20003209 NCBI chr 5:180,300,698...180,353,336
Ensembl chr 5:180,300,698...180,353,336 		JBrowse link
G GGT5 gamma-glutamyltransferase 5 increases expression ISO Isoproterenol results in increased expression of GGT5 mRNA CTD PMID:20003209 NCBI chr22:24,219,654...24,245,142
Ensembl chr22:24,219,654...24,245,108 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide increases expression ISO Isoproterenol results in increased expression of GHRL protein CTD PMID:20572026 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G GHSR growth hormone secretagogue receptor increases expression ISO Isoproterenol results in increased expression of GHSR mRNA; Isoproterenol results in increased expression of GHSR protein CTD PMID:20572026 NCBI chr 3:172,443,291...172,448,456
Ensembl chr 3:172,443,291...172,448,456 		JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 increases expression ISO Isoproterenol results in increased expression of GIGYF2 mRNA CTD PMID:20003209 NCBI chr 2:232,697,331...232,860,605
Ensembl chr 2:232,697,299...232,860,605 		JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions
decreases expression
increases expression		 ISO [Isoproterenol co-treated with Metoprolol] results in increased expression of GJA1 protein
Isoproterenol results in decreased expression of GJA1 mRNA
Isoproterenol results in increased expression of GJA1 mRNA; Isoproterenol results in increased expression of GJA1 protein
Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of GJA1 mRNA]		 CTD PMID:16352648 PMID:18089841 PMID:20003209 PMID:20215810 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GK glycerol kinase increases activity ISO Isoproterenol results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:30,653,423...30,731,462
Ensembl chr  X:30,653,359...30,731,462 		JBrowse link
G GLB1 galactosidase beta 1 multiple interactions
increases activity
affects activity		 ISO caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of GLB1 protein] CTD PMID:20391626 PMID:25560919 NCBI chr 3:32,961,108...33,097,146
Ensembl chr 3:32,996,609...33,097,202 		JBrowse link
G GLG1 golgi glycoprotein 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of GLG1 mRNA CTD PMID:30303030 NCBI chr16:74,447,440...74,607,114
Ensembl chr16:74,447,427...74,607,144 		JBrowse link
G GLUL glutamate-ammonia ligase increases expression ISO Isoproterenol results in increased expression of GLUL mRNA CTD PMID:20003209 NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206 		JBrowse link
G GNA15 G protein subunit alpha 15 increases response to substance
multiple interactions		 ISO GNA15 protein results in increased susceptibility to Isoproterenol
[GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein		 CTD PMID:9875846 NCBI chr19:3,136,033...3,163,749
Ensembl chr19:3,136,033...3,163,749 		JBrowse link
G GNAL G protein subunit alpha L multiple interactions
increases response to substance		 EXP Egtazic Acid inhibits the reaction [GNAL protein results in increased susceptibility to Isoproterenol] CTD PMID:15598656 NCBI chr18:11,689,264...11,885,685
Ensembl chr18:11,689,264...11,885,685 		JBrowse link
G GNAS GNAS complex locus multiple interactions
increases response to substance		 ISO
EXP		 GNAS protein affects the susceptibility to [Potassium Chloride co-treated with Isoproterenol]; Isoproterenol affects the expression of and affects the localization of GNAS protein
GNAS protein results in increased susceptibility to Isoproterenol
Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to Isoproterenol]		 CTD PMID:10696522 PMID:12376418 PMID:15598656 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GNG2 G protein subunit gamma 2 increases expression ISO Isoproterenol results in increased expression of GNG2 mRNA CTD PMID:20003209 NCBI chr14:51,826,174...51,969,795
Ensembl chr14:51,826,195...51,979,342 		JBrowse link
G GNG3 G protein subunit gamma 3 multiple interactions ISO [Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein CTD PMID:19136528 NCBI chr11:62,706,446...62,709,201
Ensembl chr11:62,707,676...62,709,201 		JBrowse link
G GNS glucosamine (N-acetyl)-6-sulfatase increases expression ISO Isoproterenol results in increased expression of GNS mRNA CTD PMID:20003209 NCBI chr12:64,713,449...64,759,406
Ensembl chr12:64,713,445...64,759,431 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein]; Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein CTD PMID:25496245 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 decreases expression ISO Isoproterenol results in decreased expression of GOT2 protein CTD PMID:19826179 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Isoproterenol results in decreased expression of GPAM mRNA CTD PMID:21335049 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377 		JBrowse link
G GPCPD1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO Isoproterenol results in decreased expression of GPCPD1 mRNA CTD PMID:20003209 NCBI chr20:5,544,439...5,611,006
Ensembl chr20:5,544,439...5,611,006 		JBrowse link
G GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 increases expression ISO Isoproterenol results in increased expression of GPIHBP1 mRNA CTD PMID:20003209 NCBI chr 8:143,213,218...143,217,170
Ensembl chr 8:143,213,218...143,217,170 		JBrowse link
G GPNMB glycoprotein nmb increases expression ISO Isoproterenol results in increased expression of GPNMB mRNA CTD PMID:20003209 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GPR160 G protein-coupled receptor 160 increases expression ISO Isoproterenol results in increased expression of GPR160 mRNA CTD PMID:20003209 NCBI chr 3:170,037,995...170,085,392
Ensembl chr 3:170,037,995...170,085,392 		JBrowse link
G GPR182 G protein-coupled receptor 182 increases expression ISO Isoproterenol results in increased expression of GPR182 mRNA CTD PMID:20003209 NCBI chr12:56,994,492...56,998,877
Ensembl chr12:56,994,492...56,998,447 		JBrowse link
G GPT glutamic--pyruvic transaminase increases activity
multiple interactions		 ISO Isoproterenol results in increased activity of GPT protein
Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]; imetit inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]; Isoproterenol results in increased expression of and results in increased secretion of GPT protein; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein]		 CTD PMID:25496245 PMID:26056852 PMID:35130744 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
decreases activity		 ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of GPX1 mRNA; benidipine inhibits the reaction [Isoproterenol results in decreased activity of GPX1 protein] CTD PMID:25269373 PMID:30303030 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 increases expression ISO Isoproterenol results in increased expression of GPX3 mRNA CTD PMID:20003209 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRINA glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO Isoproterenol results in increased expression of GRINA mRNA CTD PMID:20003209 NCBI chr 8:143,990,056...143,993,415
Ensembl chr 8:143,990,056...143,993,415 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 increases expression
multiple interactions		 ISO
EXP		 Isoproterenol results in increased expression of GRK2 mRNA
Isoproterenol results in increased expression of GRK2 mRNA; Isoproterenol results in increased expression of GRK2 protein
AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]		 CTD PMID:9788834 PMID:16731636 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 increases expression ISO Isoproterenol results in increased expression of GRK5 mRNA CTD PMID:20003209 NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:15951400 PMID:16716347 PMID:18806606 PMID:31009642 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases activity
increases activity
decreases expression		 ISO abana inhibits the reaction [Isoproterenol results in decreased expression of GSR]; allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; benidipine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Catechin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of GSR protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of GSR protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]
Isoproterenol results in decreased expression of GSR; Isoproterenol results in decreased expression of GSR protein		 CTD PMID:1840475 PMID:12557918 PMID:15261977 PMID:15740881 PMID:16697266 More... NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions
decreases activity		 ISO benidipine inhibits the reaction [Isoproterenol results in decreased activity of GSTA1 protein] CTD PMID:25269373 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G GSTO1 glutathione S-transferase omega 1 decreases expression ISO Isoproterenol results in decreased expression of GSTO1 mRNA CTD PMID:21335049 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459 		JBrowse link
G GTF2A1 general transcription factor IIA subunit 1 increases expression ISO Isoproterenol results in increased expression of GTF2A1 mRNA CTD PMID:20003209 NCBI chr14:81,175,452...81,221,390
Ensembl chr14:81,175,452...81,221,377 		JBrowse link
G GUSB glucuronidase beta multiple interactions
increases activity
decreases activity
increases expression		 ISO [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GUSB mRNA] CTD PMID:2015110 PMID:8534267 PMID:11829124 PMID:14499179 PMID:17045618 More... NCBI chr 7:65,960,684...65,982,213
Ensembl chr 7:65,960,684...65,982,215 		JBrowse link
G H1-2 H1.2 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F2 mRNA CTD PMID:20003209 NCBI chr 6:26,055,740...26,056,470
Ensembl chr 6:26,055,740...26,056,470 		JBrowse link
G H1-4 H1.4 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F4 mRNA CTD PMID:20003209 NCBI chr 6:26,156,329...26,157,115
Ensembl chr 6:26,156,329...26,157,115 		JBrowse link
G H19 H19 imprinted maternally expressed transcript increases expression
increases expression 		ISO Isoproterenol results in increased expression of H19 mRNA
isoprenaline increases expression of H19 RNA in cardiac muscle cells		 CTD
RGD		 PMID:20003209 PMID:27318893 RGD:156430318 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552 		JBrowse link
G H2AX H2A.X variant histone increases expression ISO Isoproterenol results in increased expression of H2AX mRNA CTD PMID:21335049 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G H3C3 H3 clustered histone 3 increases expression ISO Isoproterenol results in increased expression of H3C3 mRNA CTD PMID:20003209 NCBI chr 6:26,045,384...26,045,869
Ensembl chr 6:26,045,384...26,045,869 		JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of HADHA mRNA CTD PMID:30303030 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672 		JBrowse link
G HAGHL hydroxyacylglutathione hydrolase like decreases expression ISO Isoproterenol results in decreased expression of HAGHL mRNA CTD PMID:20003209 NCBI chr16:727,106...729,715
Ensembl chr16:726,936...735,525 		JBrowse link
G HAMP hepcidin antimicrobial peptide increases expression ISO Isoproterenol results in increased expression of HAMP mRNA CTD PMID:20211217 PMID:21335049 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143 		JBrowse link
G HAP1 huntingtin associated protein 1 increases expression ISO Isoproterenol results in increased expression of HAP1 mRNA CTD PMID:21335049 NCBI chr17:41,717,739...41,734,646
Ensembl chr17:41,717,742...41,734,644 		JBrowse link
G HARBI1 harbinger transposase derived 1 increases expression ISO Isoproterenol results in increased expression of HARBI1 mRNA CTD PMID:20003209 NCBI chr11:46,602,861...46,617,895
Ensembl chr11:46,602,861...46,617,909 		JBrowse link
G HDAC2 histone deacetylase 2 increases phosphorylation
multiple interactions		 ISO Isoproterenol results in increased phosphorylation of HDAC2 protein
plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]		 CTD PMID:31009642 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HEATR5B HEAT repeat containing 5B increases expression ISO Isoproterenol results in increased expression of HEATR5B mRNA CTD PMID:20003209 NCBI chr 2:36,980,895...37,084,372
Ensembl chr 2:36,968,383...37,084,372 		JBrowse link
G HECA hdc homolog, cell cycle regulator increases expression ISO Isoproterenol results in increased expression of HECA mRNA CTD PMID:20003209 NCBI chr 6:139,135,080...139,180,802
Ensembl chr 6:139,135,080...139,180,802 		JBrowse link
G HEPH hephaestin increases expression ISO Isoproterenol results in increased expression of HEPH mRNA CTD PMID:20003209 NCBI chr  X:66,162,671...66,268,863
Ensembl chr  X:66,162,671...66,268,867 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Isoproterenol results in increased expression of HERPUD1 mRNA CTD PMID:20003209 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G HERPUD2 HERPUD family member 2 increases expression ISO Isoproterenol results in increased expression of HERPUD2 mRNA CTD PMID:20003209 NCBI chr 7:35,632,659...35,695,135
Ensembl chr 7:35,632,659...35,697,459 		JBrowse link
G HES1 hes family bHLH transcription factor 1 decreases expression ISO Isoproterenol results in decreased expression of HES1 mRNA CTD PMID:20003209 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HEXA hexosaminidase subunit alpha increases expression ISO Isoproterenol results in increased expression of HEXA mRNA CTD PMID:20003209 NCBI chr15:72,340,924...72,376,014
Ensembl chr15:72,340,924...72,376,420 		JBrowse link
G HFE homeostatic iron regulator increases expression ISO Isoproterenol results in increased expression of HFE mRNA CTD PMID:20003209 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha decreases expression ISO Isoproterenol results in decreased expression of HIF1A mRNA CTD PMID:20003209 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor decreases expression EXP Isoproterenol results in decreased expression of HIF1AN mRNA CTD PMID:24286936 NCBI chr10:100,535,943...100,559,998
Ensembl chr10:100,529,072...100,559,998 		JBrowse link
G HIF3A hypoxia inducible factor 3 subunit alpha increases expression EXP
ISO		 Isoproterenol results in increased expression of HIF3A mRNA CTD PMID:24286936 NCBI chr19:46,297,042...46,343,433
Ensembl chr19:46,297,042...46,343,433 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 increases expression ISO Isoproterenol results in increased expression of HIPK1 mRNA CTD PMID:20003209 NCBI chr 1:113,929,324...113,977,869
Ensembl chr 1:113,929,324...113,977,869 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 decreases expression ISO Isoproterenol results in decreased expression of HIPK2 mRNA CTD PMID:20003209 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998 		JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 increases expression ISO Isoproterenol results in increased expression of HIPK3 mRNA CTD PMID:20003209 NCBI chr11:33,256,672...33,357,023
Ensembl chr11:33,256,672...33,357,023 		JBrowse link
G HK2 hexokinase 2 decreases expression ISO Isoproterenol results in decreased expression of HK2 mRNA CTD PMID:20003209 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HLA-DMA major histocompatibility complex, class II, DM alpha decreases expression ISO Isoproterenol results in decreased expression of H2-DMA mRNA CTD PMID:20003209 NCBI chr 6:32,948,618...32,953,097
Ensembl chr 6:32,948,613...32,969,094 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 decreases expression ISO Isoproterenol results in decreased expression of H2-AA mRNA CTD PMID:20003209 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 decreases expression ISO Isoproterenol results in decreased expression of H2-AB1 mRNA CTD PMID:20003209 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 decreases expression ISO Isoproterenol results in decreased expression of H2-EB1 mRNA CTD PMID:20003209 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848 		JBrowse link
G HLF HLF transcription factor, PAR bZIP family member decreases expression ISO Isoproterenol results in decreased expression of HLF mRNA CTD PMID:20003209 NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases activity		 ISO 7-hydroxycoumarin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; alliin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:16640830 PMID:16906524 PMID:19595682 PMID:26995004 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Isoproterenol results in increased expression of HMGCS1 mRNA CTD PMID:21335049 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
decreases expression
increases expression		 EXP
ISO		 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]
Isoproterenol results in decreased expression of HMOX1 mRNA; Isoproterenol results in decreased expression of HMOX1 protein
Isoproterenol results in increased expression of HMOX1 mRNA; Isoproterenol results in increased expression of HMOX1 protein
[erdosteine co-treated with Isoproterenol] results in increased expression of HMOX1 protein; anethole promotes the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]; anethole promotes the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Doxorubicin inhibits the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 protein]		 CTD PMID:15179140 PMID:19483313 PMID:20003209 PMID:21823215 PMID:22908232 More... NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 decreases expression ISO Isoproterenol results in decreased expression of HNRNPH3 mRNA CTD PMID:20003209 NCBI chr10:68,331,693...68,343,196
Ensembl chr10:68,331,174...68,343,193 		JBrowse link
G HNRNPR heterogeneous nuclear ribonucleoprotein R decreases expression ISO Isoproterenol results in decreased expression of HNRNPR mRNA CTD PMID:20003209 NCBI chr 1:23,304,688...23,344,284
Ensembl chr 1:23,303,771...23,344,336 		JBrowse link
G HOMER1 homer scaffold protein 1 increases expression ISO Isoproterenol results in increased expression of HOMER1 mRNA alternative form CTD PMID:16786172 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134 		JBrowse link
G HOPX HOP homeobox decreases expression ISO Isoproterenol results in decreased expression of HOPX mRNA CTD PMID:20003209 NCBI chr 4:56,647,998...56,681,706
Ensembl chr 4:56,647,989...56,681,877 		JBrowse link
G HPCA hippocalcin affects localization ISO Isoproterenol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441 		JBrowse link
G HPSE heparanase increases expression ISO Isoproterenol results in increased expression of HPSE protein CTD PMID:16327176 NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153 		JBrowse link
G HRAS HRas proto-oncogene, GTPase increases activity ISO Isoproterenol results in increased activity of HRAS protein CTD PMID:8484791 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321 		JBrowse link
G HS2ST1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Isoproterenol results in decreased expression of HS2ST1 mRNA CTD PMID:20003209 NCBI chr 1:86,914,635...87,109,982
Ensembl chr 1:86,914,635...87,109,982 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isoproterenol results in decreased expression of HSD3B1 mRNA CTD PMID:21335049 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression ISO Isoproterenol results in increased expression of HSP90AA1 mRNA CTD PMID:21335049 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 decreases expression ISO Isoproterenol results in decreased expression of HSP90B1 mRNA CTD PMID:20003209 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931 		JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of HSPA1L mRNA
Isoproterenol results in decreased expression of HSPA1L mRNA		 CTD PMID:20003209 PMID:24286936 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 increases expression ISO
EXP		 Isoproterenol results in increased expression of HSPA2 mRNA CTD PMID:20211217 PMID:24286936 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of HSPA5 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]]
Isoproterenol results in decreased expression of HSPA5 mRNA		 CTD PMID:21335049 PMID:24286936 PMID:29414845 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 decreases expression ISO
EXP		 Isoproterenol results in decreased expression of HSPA8 mRNA CTD PMID:20003209 PMID:24286936 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions
increases expression		 ISO Curcumin promotes the reaction [Isoproterenol results in increased expression of HSPB1 protein]
Isoproterenol results in increased expression of HSP27 protein; Isoproterenol results in increased expression of HSPB1 protein		 CTD PMID:10559386 PMID:20125031 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPB7 heat shock protein family B (small) member 7 increases expression ISO Isoproterenol results in increased expression of HSPB7 mRNA CTD PMID:24286936 NCBI chr 1:16,014,029...16,019,594
Ensembl chr 1:16,014,028...16,019,594 		JBrowse link
G HSPG2 heparan sulfate proteoglycan 2 decreases expression ISO Isoproterenol results in decreased expression of HSPG2 mRNA CTD PMID:20003209 NCBI chr 1:21,822,244...21,937,310
Ensembl chr 1:21,822,244...21,937,310 		JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression ISO Isoproterenol results in increased expression of HSPH1 mRNA CTD PMID:21335049 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388 		JBrowse link
G HTRA2 HtrA serine peptidase 2 decreases expression ISO Isoproterenol results in decreased expression of HTRA2 mRNA CTD PMID:21335049 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350 		JBrowse link
G HTRA3 HtrA serine peptidase 3 increases expression ISO Isoproterenol results in increased expression of HTRA3 mRNA CTD PMID:20003209 NCBI chr 4:8,269,754...8,307,098
Ensembl chr 4:8,269,754...8,307,098 		JBrowse link
G HYOU1 hypoxia up-regulated 1 decreases expression ISO Isoproterenol results in decreased expression of HYOU1 mRNA CTD PMID:20003209 NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression ISO Isoproterenol results in increased expression of ICAM1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID1 inhibitor of DNA binding 1 decreases expression
increases expression 		ISO Isoproterenol results in decreased expression of ID1 mRNA
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes		 CTD
RGD		 PMID:21335049 PMID:26873969 RGD:11526363 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515 		JBrowse link
G IER3 immediate early response 3 multiple interactions
affects response to substance		 ISO IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Pertussis Toxin affects the reaction [IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]]; Pertussis Toxin affects the reaction [IER3 protein affects the susceptibility to Isoproterenol] CTD PMID:20713914 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G IFNA1 interferon alpha 1 decreases expression ISO Isoproterenol results in decreased expression of IFNA1 mRNA CTD PMID:24286936 NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316 		JBrowse link
G IFNG interferon gamma decreases secretion EXP Isoproterenol results in decreased secretion of IFNG protein CTD PMID:15342205 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IFNGR2 interferon gamma receptor 2 decreases expression ISO Isoproterenol results in decreased expression of IFNGR2 mRNA CTD PMID:20003209 NCBI chr21:33,402,882...33,437,516
Ensembl chr21:33,403,413...33,479,348 		JBrowse link
G IFRD1 interferon related developmental regulator 1 increases expression ISO Isoproterenol results in increased expression of IFRD1 mRNA CTD PMID:20003209 NCBI chr 7:112,423,174...112,477,203
Ensembl chr 7:112,422,887...112,481,017 		JBrowse link
G IFT74 intraflagellar transport 74 increases expression ISO Isoproterenol results in increased expression of IFT74 mRNA CTD PMID:20003209 NCBI chr 9:26,947,110...27,066,134
Ensembl chr 9:26,947,039...27,066,134 		JBrowse link
G IGF1 insulin like growth factor 1 decreases expression
increases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of IGF1 mRNA
Isoproterenol results in increased expression of IGF1 mRNA; Isoproterenol results in increased expression of IGF1 protein
candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 mRNA]; candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 protein]		 CTD PMID:10547078 PMID:20003209 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor increases expression ISO Isoproterenol results in increased expression of IGF1R mRNA CTD PMID:20003209 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 increases expression ISO Isoproterenol results in increased expression of IGF2BP2 mRNA CTD PMID:20003209 NCBI chr 3:185,643,130...185,825,042
Ensembl chr 3:185,643,130...185,825,042 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of IGFBP3
SI 27 inhibits the reaction [Isoproterenol results in decreased expression of IGFBP3]		 CTD PMID:12883319 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G IL10 interleukin 10 multiple interactions
decreases expression		 ISO Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Quercetin inhibits the reaction [Isoproterenol results in decreased expression of IL10 protein]		 CTD PMID:9038718 PMID:27527349 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12A interleukin 12A decreases expression ISO Isoproterenol results in decreased expression of IL12A protein CTD PMID:24286936 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL12B interleukin 12B increases expression EXP Isoproterenol results in increased expression of IL12B protein CTD PMID:24286936 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL17A interleukin 17A increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of IL17A protein
Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL17A protein]		 CTD PMID:19909738 PMID:35305975 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL17RD interleukin 17 receptor D increases expression ISO Isoproterenol results in increased expression of IL17RD mRNA CTD PMID:20003209 NCBI chr 3:57,089,982...57,170,317
Ensembl chr 3:57,089,982...57,170,306 		JBrowse link
G IL18 interleukin 18 multiple interactions
increases expression
decreases expression		 ISO ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL18 protein; Isoproterenol results in increased expression of and results in increased stability of IL18 mRNA; Pertussis Toxin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; wortmannin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]
Isoproterenol results in decreased expression of IL18 mRNA		 CTD PMID:15178407 PMID:21335049 PMID:24286936 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha decreases expression
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of IL1A mRNA
Isoproterenol results in increased expression of IL1A mRNA		 CTD PMID:24286936 PMID:32816093 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases expression
increases expression		 ISO
EXP		 SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL1B]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]
Isoproterenol results in decreased expression of IL1B mRNA
Isoproterenol results in decreased expression of IL1B mRNA; Isoproterenol results in decreased expression of IL1B protein
Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]]		 CTD PMID:9387890 PMID:12215284 PMID:15302781 PMID:18487443 PMID:19023134 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist affects response to substance EXP IL1RN protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of IL2 mRNA; Isoproterenol results in increased expression of IL2 protein
Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]]		 CTD PMID:25045214 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL24 interleukin 24 increases expression EXP Isoproterenol results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139 		JBrowse link
G IL4 interleukin 4 decreases expression
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 protein		 CTD PMID:24286936 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL4R interleukin 4 receptor increases expression ISO Isoproterenol results in increased expression of IL4RA mRNA CTD PMID:20003209 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778 		JBrowse link
G IL5RA interleukin 5 receptor subunit alpha affects response to substance EXP IL5RA protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 3:3,066,324...3,110,374
Ensembl chr 3:3,066,324...3,126,613 		JBrowse link
G IL6 interleukin 6 multiple interactions
increases secretion
increases expression
decreases expression
decreases secretion		 ISO
EXP		 ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]; biochanin A inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Genistein promotes the reaction [Isoproterenol results in increased secretion of IL6 protein]; Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; oxophenylarsine inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL6]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
Isoproterenol results in decreased expression of IL6 mRNA
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Isoproterenol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL6 protein; Metformin inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL6 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in increased expression of IL6; Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]		 CTD PMID:9038718 PMID:9688336 PMID:10525314 PMID:11406463 PMID:15302781 More... NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7 interleukin 7 increases expression EXP
ISO		 Isoproterenol results in increased expression of IL7 protein CTD PMID:24286936 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
G IMMT inner membrane mitochondrial protein decreases expression ISO Isoproterenol results in decreased expression of IMMT mRNA CTD PMID:20003209 NCBI chr 2:86,143,936...86,195,462
Ensembl chr 2:86,143,932...86,195,472 		JBrowse link
G INHBB inhibin subunit beta B increases expression ISO Isoproterenol results in increased expression of INHBB mRNA CTD PMID:20003209 NCBI chr 2:120,346,136...120,351,803
Ensembl chr 2:120,346,136...120,351,803 		JBrowse link
G INS insulin multiple interactions
increases expression
affects expression		 ISO INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; OPC 3911 inhibits the reaction [INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]]
Isoproterenol results in increased expression of INS protein
Isoproterenol affects the expression of INS protein		 CTD PMID:1129332 PMID:1170870 PMID:19167487 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INTS3 integrator complex subunit 3 increases expression ISO Isoproterenol results in increased expression of INTS3 mRNA CTD PMID:20003209 NCBI chr 1:153,728,050...153,774,808
Ensembl chr 1:153,728,050...153,774,808 		JBrowse link
G IPO13 importin 13 decreases expression ISO Isoproterenol results in decreased expression of IPO13 mRNA CTD PMID:20003209 NCBI chr 1:43,946,950...43,968,022
Ensembl chr 1:43,946,950...43,968,022 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 increases expression ISO Isoproterenol results in increased expression of IRAK3 mRNA CTD PMID:20003209 NCBI chr12:66,189,214...66,254,622
Ensembl chr12:66,189,195...66,254,622 		JBrowse link
G IRS1 insulin receptor substrate 1 increases expression ISO Isoproterenol results in increased expression of IRS1 mRNA CTD PMID:20003209 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820 		JBrowse link
G IRX4 iroquois homeobox 4 decreases expression ISO Isoproterenol results in decreased expression of IRX4 mRNA CTD PMID:20003209 NCBI chr 5:1,877,413...1,887,179
Ensembl chr 5:1,877,413...1,887,236 		JBrowse link
G ITGAM integrin subunit alpha M multiple interactions EXP Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]] CTD PMID:9762784 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITGB1 integrin subunit beta 1 multiple interactions
decreases expression		 ISO DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of ITGB1		 CTD PMID:18340010 PMID:18808529 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G ITGBL1 integrin subunit beta like 1 increases expression ISO Isoproterenol results in increased expression of ITGBL1 mRNA CTD PMID:20003209 NCBI chr13:101,452,675...101,720,856
Ensembl chr13:101,452,593...101,720,856 		JBrowse link
G ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 increases expression ISO Isoproterenol results in increased expression of ITIH3 mRNA CTD PMID:20003209 NCBI chr 3:52,794,796...52,808,797
Ensembl chr 3:52,794,768...52,808,799 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression ISO Isoproterenol results in increased expression of ITIH4 mRNA CTD PMID:20003209 NCBI chr 3:52,812,962...52,830,672
Ensembl chr 3:52,812,962...52,830,688 		JBrowse link
G ITK IL2 inducible T cell kinase decreases expression ISO Isoproterenol results in decreased expression of ITK mRNA CTD PMID:20003209 NCBI chr 5:157,180,840...157,255,185
Ensembl chr 5:157,142,933...157,255,185 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B decreases expression ISO Isoproterenol results in decreased expression of ITPKB mRNA CTD PMID:20003209 NCBI chr 1:226,631,690...226,739,282
Ensembl chr 1:226,631,690...226,739,323 		JBrowse link
G JADE2 jade family PHD finger 2 increases expression ISO Isoproterenol results in increased expression of JADE2 mRNA CTD PMID:20003209 NCBI chr 5:134,523,952...134,583,227
Ensembl chr 5:134,524,312...134,583,230 		JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 decreases expression ISO Isoproterenol results in decreased expression of JARID2 mRNA CTD PMID:20003209 NCBI chr 6:15,246,069...15,522,042
Ensembl chr 6:15,246,069...15,522,042 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression		 ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]
Isoproterenol results in decreased expression of JUN mRNA
Isoproterenol results in increased expression of JUN mRNA; Isoproterenol results in increased expression of JUN protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of JUN mRNA; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]		 CTD PMID:10710348 PMID:14764439 PMID:21177286 PMID:30303030 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of JUNB
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]
Isoproterenol results in increased expression of JUNB mRNA; Isoproterenol results in increased expression of JUNB protein		 CTD PMID:7905536 PMID:21177286 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KANK3 KN motif and ankyrin repeat domains 3 increases expression ISO Isoproterenol results in increased expression of KANK3 mRNA CTD PMID:20003209 NCBI chr19:8,322,584...8,343,262
Ensembl chr19:8,322,584...8,343,262 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 increases expression ISO Isoproterenol results in increased expression of KCNA5 mRNA CTD PMID:20003209 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Isoproterenol results in decreased expression of KCNB1 mRNA CTD PMID:20003209 NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Isoproterenol results in decreased expression of KCND2 mRNA CTD PMID:20003209 NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions
decreases expression		 EXP
ISO		 Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
Isoproterenol results in decreased expression of KCNE1 mRNA		 CTD PMID:16909339 PMID:20003209 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214 		JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 increases expression ISO Isoproterenol results in increased expression of KCNH6 mRNA CTD PMID:20003209 NCBI chr17:63,523,358...63,548,992
Ensembl chr17:63,523,334...63,548,977 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 multiple interactions EXP
ISO		 Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of KCNQ1 mRNA		 CTD PMID:16909339 PMID:30303030 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G KCNT2 potassium sodium-activated channel subfamily T member 2 increases expression ISO Isoproterenol results in increased expression of KCNT2 mRNA CTD PMID:20003209 NCBI chr 1:196,225,779...196,608,440
Ensembl chr 1:196,225,779...196,609,225 		JBrowse link
G KDM6B lysine demethylase 6B decreases expression ISO Isoproterenol results in decreased expression of KDM6B mRNA CTD PMID:20003209 NCBI chr17:7,834,217...7,854,796
Ensembl chr17:7,834,217...7,854,796 		JBrowse link
G KDR kinase insert domain receptor decreases expression ISO Isoproterenol results in decreased expression of KDR mRNA CTD PMID:20003209 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 decreases expression
increases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of KEAP1 mRNA
Isoproterenol results in increased expression of KEAP1 mRNA; Isoproterenol results in increased expression of KEAP1 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA; anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of KEAP1 protein]		 CTD PMID:30303030 PMID:35430261 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KIF1B kinesin family member 1B decreases expression ISO Isoproterenol results in decreased expression of KIF1B mRNA CTD PMID:20003209 NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603 		JBrowse link
G KLF15 KLF transcription factor 15 increases expression ISO Isoproterenol results in increased expression of KLF15 mRNA CTD PMID:20003209 NCBI chr 3:126,288,125...126,357,408
Ensembl chr 3:126,342,635...126,357,408 		JBrowse link
G KLF3 KLF transcription factor 3 increases expression ISO Isoproterenol results in increased expression of KLF3 mRNA CTD PMID:20003209 NCBI chr 4:38,664,199...38,701,517
Ensembl chr 4:38,664,197...38,701,517 		JBrowse link
G KLHDC8A kelch domain containing 8A decreases expression ISO Isoproterenol results in decreased expression of KLHDC8A mRNA CTD PMID:20003209 NCBI chr 1:205,336,061...205,357,039
Ensembl chr 1:205,336,061...205,357,090 		JBrowse link
G KLHL2 kelch like family member 2 increases expression ISO Isoproterenol results in increased expression of KLHL2 mRNA CTD PMID:20003209 NCBI chr 4:165,207,561...165,323,156
Ensembl chr 4:165,207,561...165,323,156 		JBrowse link
G KLHL24 kelch like family member 24 increases expression ISO Isoproterenol results in increased expression of KLHL24 mRNA CTD PMID:20003209 NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519 		JBrowse link
G KLHL40 kelch like family member 40 increases expression ISO Isoproterenol results in increased expression of KLHL40 mRNA CTD PMID:20211217 NCBI chr 3:42,685,537...42,692,544
Ensembl chr 3:42,685,537...42,692,544 		JBrowse link
G KLHL41 kelch like family member 41 increases expression ISO Isoproterenol results in increased expression of KLHL41 mRNA CTD PMID:20211217 NCBI chr 2:169,509,702...169,526,258
Ensembl chr 2:169,509,702...169,526,258 		JBrowse link
G KLHL7 kelch like family member 7 increases expression ISO Isoproterenol results in increased expression of KLHL7 mRNA CTD PMID:20003209 NCBI chr 7:23,105,785...23,177,914
Ensembl chr 7:23,105,758...23,177,914 		JBrowse link
G KMT5A lysine methyltransferase 5A decreases expression ISO Isoproterenol results in decreased expression of KMT5A mRNA CTD PMID:20003209 NCBI chr12:123,384,132...123,409,353
Ensembl chr12:123,384,132...123,409,353 		JBrowse link
G KPNA3 karyopherin subunit alpha 3 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA3 mRNA CTD PMID:30303030 NCBI chr13:49,699,320...49,792,682
Ensembl chr13:49,699,320...49,792,682 		JBrowse link
G KPNA6 karyopherin subunit alpha 6 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA6 mRNA CTD PMID:30303030 NCBI chr 1:32,108,056...32,176,563
Ensembl chr 1:32,108,056...32,176,563 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase increases expression ISO Isoproterenol results in increased expression of KRAS mRNA CTD PMID:21335049 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KRT18 keratin 18 increases expression ISO Isoproterenol results in increased expression of KRT18 mRNA CTD PMID:21335049 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906 		JBrowse link
G KRT222 keratin 222 decreases expression ISO Isoproterenol results in decreased expression of KRT222 mRNA CTD PMID:20003209 NCBI chr17:40,654,665...40,665,177
Ensembl chr17:40,654,665...40,665,181 		JBrowse link
G KY kyphoscoliosis peptidase decreases expression ISO Isoproterenol results in decreased expression of KY mRNA CTD PMID:20003209 NCBI chr 3:134,599,923...134,651,022
Ensembl chr 3:134,599,923...134,651,636 		JBrowse link
G LAMA2 laminin subunit alpha 2 decreases expression ISO Isoproterenol results in decreased expression of LAMA2 CTD PMID:18808529 NCBI chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566 		JBrowse link
G LAMB1 laminin subunit beta 1 decreases expression ISO Isoproterenol results in decreased expression of LAMB1 mRNA CTD PMID:20003209 NCBI chr 7:107,923,799...108,003,161
Ensembl chr 7:107,923,799...108,003,213 		JBrowse link
G LBH LBH regulator of WNT signaling pathway decreases expression ISO Isoproterenol results in decreased expression of LBH mRNA CTD PMID:20003209 NCBI chr 2:30,231,534...30,260,028
Ensembl chr 2:30,231,534...30,323,730 		JBrowse link
G LBP lipopolysaccharide binding protein increases expression ISO Isoproterenol results in increased expression of LBP mRNA CTD PMID:20003209 PMID:21335049 NCBI chr20:38,346,482...38,377,013
Ensembl chr20:38,346,482...38,377,013 		JBrowse link
G LCAT lecithin-cholesterol acyltransferase multiple interactions
decreases activity		 ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; alliin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:15740881 PMID:16640830 PMID:16906524 PMID:19595682 PMID:20024955 NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131 		JBrowse link
G LCN2 lipocalin 2 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of LCN2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LDHA lactate dehydrogenase A multiple interactions
increases expression
increases secretion		 ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; benidipine inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHA protein]; Isoproterenol results in increased expression of and results in increased secretion of LDHA protein; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of LDHA protein] CTD PMID:17188415 PMID:19146839 PMID:21322096 PMID:21472895 PMID:21671307 More... NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LDHB lactate dehydrogenase B multiple interactions
increases expression
increases secretion		 ISO [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHB protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:17188415 PMID:19146839 PMID:21322096 PMID:21472895 PMID:21671307 NCBI chr12:21,635,342...21,657,842
Ensembl chr12:21,635,342...21,757,857 		JBrowse link
G LEP leptin decreases secretion
increases secretion
increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in decreased secretion of LEP protein
Isoproterenol results in increased secretion of LEP protein
Isoproterenol results in increased expression of LEP protein
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEP protein]
Propranolol inhibits the reaction [Isoproterenol results in decreased secretion of LEP protein]		 CTD PMID:11022189 PMID:20307649 PMID:25111128 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor multiple interactions
increases expression		 ISO CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR protein]
Isoproterenol results in increased expression of LEPR mRNA; Isoproterenol results in increased expression of LEPR protein		 CTD PMID:20307649 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LGALS3 galectin 3 increases expression ISO Isoproterenol results in increased expression of LGALS3 mRNA CTD PMID:20003209 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LGI1 leucine rich glioma inactivated 1 decreases expression ISO Isoproterenol results in decreased expression of LGI1 mRNA CTD PMID:20003209 NCBI chr10:93,757,936...93,798,159
Ensembl chr10:93,757,840...93,806,272 		JBrowse link
G LGR6 leucine rich repeat containing G protein-coupled receptor 6 decreases expression ISO Isoproterenol results in decreased expression of LGR6 mRNA CTD PMID:20003209 NCBI chr 1:202,193,799...202,319,761
Ensembl chr 1:202,193,799...202,319,781 		JBrowse link
G LILRB3 leukocyte immunoglobulin like receptor B3 increases expression ISO Isoproterenol results in increased expression of LILRB3 mRNA CTD PMID:20003209 NCBI chr19:54,216,278...54,223,007
Ensembl chr19:54,216,278...54,223,506 		JBrowse link
G LIMD1 LIM domain containing 1 increases expression ISO Isoproterenol results in increased expression of LIMD1 mRNA CTD PMID:20003209 NCBI chr 3:45,594,751...45,686,341
Ensembl chr 3:45,555,394...45,686,341 		JBrowse link
G LIN7A lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Isoproterenol results in increased expression of LIN7A mRNA CTD PMID:20003209 NCBI chr12:80,792,520...80,937,934
Ensembl chr12:80,792,520...80,937,934 		JBrowse link
G LIPE lipase E, hormone sensitive type increases phosphorylation
affects localization
multiple interactions
increases activity		 ISO Isoproterenol results in increased phosphorylation of LIPE protein
Isoproterenol affects the localization of LIPE protein
Papaverine inhibits the reaction [Isoproterenol affects the localization of LIPE protein]; Papaverine inhibits the reaction [Isoproterenol results in increased activity of LIPE protein]
Sirolimus promotes the reaction [Isoproterenol results in increased phosphorylation of LIPE protein]		 CTD PMID:10894095 PMID:11160373 PMID:21042876 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388 		JBrowse link
G LITAF lipopolysaccharide induced TNF factor increases expression ISO Isoproterenol results in increased expression of LITAF mRNA CTD PMID:20003209 PMID:21335049 NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381 		JBrowse link
G LMAN1 lectin, mannose binding 1 increases expression ISO Isoproterenol results in increased expression of LMAN1 mRNA CTD PMID:21823215 NCBI chr18:59,327,823...59,359,265
Ensembl chr18:59,327,823...59,359,265 		JBrowse link
G LMCD1 LIM and cysteine rich domains 1 increases expression ISO Isoproterenol results in increased expression of LMCD1 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr 3:8,501,823...8,574,668
Ensembl chr 3:8,501,807...8,574,668 		JBrowse link
G LMOD3 leiomodin 3 decreases expression ISO Isoproterenol results in decreased expression of LMOD3 mRNA CTD PMID:20003209 NCBI chr 3:69,106,065...69,122,595
Ensembl chr 3:69,106,065...69,123,032 		JBrowse link
G LONRF3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO Isoproterenol results in increased expression of LONRF3 mRNA CTD PMID:20003209 NCBI chr  X:118,974,614...119,018,355
Ensembl chr  X:118,974,614...119,018,355 		JBrowse link
G LOX lysyl oxidase increases expression ISO Isoproterenol results in increased expression of LOX mRNA CTD PMID:20003209 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413 		JBrowse link
G LPL lipoprotein lipase multiple interactions
decreases expression
increases expression
decreases activity		 ISO cirazoline promotes the reaction [Isoproterenol results in increased expression of LPL mRNA]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LPL protein]
Isoproterenol results in decreased expression of LPL mRNA		 CTD PMID:9032464 PMID:16906524 PMID:21335049 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G LRAT lecithin retinol acyltransferase decreases expression ISO Isoproterenol results in decreased expression of LRAT mRNA CTD PMID:20003209 NCBI chr 4:154,740,838...154,753,120
Ensembl chr 4:154,626,945...154,753,120 		JBrowse link
G LRG1 leucine rich alpha-2-glycoprotein 1 increases expression ISO Isoproterenol results in increased expression of LRG1 mRNA CTD PMID:20003209 NCBI chr19:4,536,402...4,540,036
Ensembl chr19:4,536,402...4,540,036 		JBrowse link
G LRPPRC leucine rich pentatricopeptide repeat containing multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of LRPPRC mRNA CTD PMID:30303030 NCBI chr 2:43,886,224...43,996,265
Ensembl chr 2:43,886,224...43,996,226 		JBrowse link
G LRRC52 leucine rich repeat containing 52 increases expression ISO Isoproterenol results in increased expression of LRRC52 mRNA CTD PMID:20003209 NCBI chr 1:165,544,000...165,563,957
Ensembl chr 1:165,544,000...165,563,957 		JBrowse link
G LRRC58 leucine rich repeat containing 58 increases expression ISO Isoproterenol results in increased expression of LRRC58 mRNA CTD PMID:20003209 NCBI chr 3:120,324,509...120,349,354
Ensembl chr 3:120,324,509...120,349,354 		JBrowse link
G LRRC8C leucine rich repeat containing 8 VRAC subunit C increases expression ISO Isoproterenol results in increased expression of LRRC8C mRNA CTD PMID:20003209 NCBI chr 1:89,615,824...89,719,533
Ensembl chr 1:89,633,072...89,769,903 		JBrowse link
G LSM14A LSM14A mRNA processing body assembly factor increases expression ISO Isoproterenol results in increased expression of LSM14A mRNA CTD PMID:20003209 NCBI chr19:34,172,504...34,229,288
Ensembl chr19:34,172,504...34,229,288 		JBrowse link
G LSM3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Isoproterenol results in decreased expression of LSM3 mRNA CTD PMID:20003209 NCBI chr 3:14,178,817...14,201,122
Ensembl chr 3:14,178,817...14,201,122 		JBrowse link
G LTBP2 latent transforming growth factor beta binding protein 2 increases expression
increases expression 		ISO Isoproterenol results in increased expression of LTBP2 mRNA
Isoproterenol increases expression of Ltbp2 mRNA in the heart		 CTD
RGD		 PMID:20003209 PMID:29950403 RGD:156451654 NCBI chr14:74,498,183...74,612,237
Ensembl chr14:74,498,183...74,612,378 		JBrowse link
G LY6S lymphocyte antigen 6 family member S increases expression ISO Isoproterenol results in increased expression of LY6A mRNA CTD PMID:20003209 NCBI chr 8:143,040,839...143,076,471
Ensembl chr 8:143,041,844...143,045,678 		JBrowse link
G LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 increases expression ISO Isoproterenol results in increased expression of LYVE1 mRNA CTD PMID:20003209 NCBI chr11:10,556,966...10,568,665
Ensembl chr11:10,556,966...10,611,689 		JBrowse link
G MAF MAF bZIP transcription factor increases expression ISO Isoproterenol results in increased expression of MAF mRNA CTD PMID:30303030 NCBI chr16:79,202,622...79,600,737
Ensembl chr16:79,585,843...79,600,737 		JBrowse link
G MAFF MAF bZIP transcription factor F increases expression ISO Isoproterenol results in increased expression of MAFF mRNA CTD PMID:20003209 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507 		JBrowse link
G MAN1A1 mannosidase alpha class 1A member 1 increases expression ISO Isoproterenol results in increased expression of MAN1A mRNA CTD PMID:20003209 NCBI chr 6:119,177,205...119,350,605
Ensembl chr 6:119,177,205...119,349,761 		JBrowse link
G MAN2A1 mannosidase alpha class 2A member 1 increases expression ISO Isoproterenol results in increased expression of MAN2A1 mRNA CTD PMID:20003209 NCBI chr 5:109,689,927...109,869,625
Ensembl chr 5:109,689,927...109,869,625 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:10888249 PMID:21177286 NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP2K4 mRNA CTD PMID:30303030 NCBI chr17:12,020,877...12,143,828
Ensembl chr17:12,020,829...12,143,830 		JBrowse link
G MAP3K2 mitogen-activated protein kinase kinase kinase 2 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of MAP3K2 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP3K2 mRNA		 CTD PMID:30303030 NCBI chr 2:127,298,668...127,388,465
Ensembl chr 2:127,298,668...127,388,465 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Isoproterenol results in decreased expression of MAP3K5 mRNA CTD PMID:21335049 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097 		JBrowse link
G MAP3K6 mitogen-activated protein kinase kinase kinase 6 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K6 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 1:27,355,184...27,366,961
Ensembl chr 1:27,355,184...27,366,961 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K8 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833 		JBrowse link
G MAP7 microtubule associated protein 7 increases expression ISO Isoproterenol results in increased expression of MAP7 mRNA CTD PMID:20003209 NCBI chr 6:136,342,734...136,550,422
Ensembl chr 6:136,342,281...136,550,819 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases activity
increases phosphorylation
multiple interactions		 ISO
EXP		 Isoproterenol results in increased activity of MAPK1 protein
Isoproterenol results in increased phosphorylation of MAPK1 protein
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
erdosteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK1 protein; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK1 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
[Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:10888249 PMID:11093795 PMID:15292328 PMID:16980553 PMID:17623046 More... NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions
increases phosphorylation		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein] CTD PMID:18089841 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases expression
increases phosphorylation
increases activity		 EXP
ISO		 [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein]
Isoproterenol results in increased expression of MAPK3 mRNA
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
erdosteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK3 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK3 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of MAPK3 protein; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK3 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:10888249 PMID:11093795 PMID:15292328 PMID:16980553 PMID:17623046 More... NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases expression
increases activity
increases phosphorylation		 ISO candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]
Isoproterenol results in increased expression of MAPK8 mRNA
Isoproterenol results in increased activity of MAPK8 protein
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MAPK8 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]		 CTD PMID:10591028 PMID:15951400 PMID:20562518 PMID:35608392 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 increases expression ISO Isoproterenol results in increased expression of MARCHF7 mRNA CTD PMID:20003209 NCBI chr 2:159,712,506...159,771,027
Ensembl chr 2:159,712,457...159,771,027 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression ISO Isoproterenol results in decreased expression of MAS1 protein CTD PMID:20409916 NCBI chr 6:159,888,787...159,917,447
Ensembl chr 6:159,890,988...159,917,447 		JBrowse link
G MB myoglobin increases expression
multiple interactions
increases secretion		 ISO Isoproterenol results in increased expression of MB protein
sinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein]
Isoproterenol results in increased secretion of MB protein		 CTD PMID:533011 PMID:19628585 PMID:32627257 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951 		JBrowse link
G MBD1 methyl-CpG binding domain protein 1 increases expression ISO Isoproterenol results in increased expression of MBD1 mRNA CTD PMID:20003209 NCBI chr18:50,266,885...50,281,767
Ensembl chr18:50,266,882...50,281,774 		JBrowse link
G MBD5 methyl-CpG binding domain protein 5 increases expression ISO Isoproterenol results in increased expression of MBD5 mRNA CTD PMID:20003209 NCBI chr 2:148,020,927...148,516,971
Ensembl chr 2:148,021,011...148,516,971 		JBrowse link
G MCCC2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression ISO Isoproterenol results in decreased expression of MCCC2 mRNA CTD PMID:20003209 NCBI chr 5:71,587,340...71,658,706
Ensembl chr 5:71,579,531...71,658,706 		JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like increases expression ISO Isoproterenol results in increased expression of MCF2L mRNA CTD PMID:20003209 NCBI chr13:112,894,335...113,099,742
Ensembl chr13:112,894,378...113,099,742 		JBrowse link
G MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 decreases expression ISO Isoproterenol results in decreased expression of MDGA1 mRNA CTD PMID:20003209 NCBI chr 6:37,630,679...37,697,883
Ensembl chr 6:37,630,679...37,699,306 		JBrowse link
G MEF2C myocyte enhancer factor 2C decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of MEF2C mRNA
Isoproterenol results in increased expression of MEF2C mRNA		 CTD PMID:20003209 PMID:30303030 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MEIG1 meiosis/spermiogenesis associated 1 decreases expression ISO Isoproterenol results in decreased expression of MEIG1 mRNA CTD PMID:20003209 NCBI chr10:14,954,228...14,988,050
Ensembl chr10:14,959,388...14,988,050 		JBrowse link
G METRN meteorin, glial cell differentiation regulator decreases expression ISO Isoproterenol results in decreased expression of METRN mRNA CTD PMID:20003209 NCBI chr16:715,118...719,655
Ensembl chr16:715,118...719,655 		JBrowse link
G MFAP5 microfibril associated protein 5 increases expression ISO Isoproterenol results in increased expression of MFAP5 mRNA CTD PMID:20003209 NCBI chr12:8,645,943...8,662,826
Ensembl chr12:8,637,346...8,662,888 		JBrowse link
G MFN1 mitofusin 1 decreases expression ISO Isoproterenol results in decreased expression of MFN1 protein CTD PMID:27491814 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MFN2 mitofusin 2 decreases expression ISO Isoproterenol results in decreased expression of MFN2 protein CTD PMID:26692091 PMID:27491814 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MGLL monoglyceride lipase decreases expression ISO Isoproterenol results in decreased expression of MGLL mRNA CTD PMID:20003209 NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190 		JBrowse link
G MGP matrix Gla protein increases expression ISO Isoproterenol results in increased expression of MGP mRNA CTD PMID:20003209 NCBI chr12:14,880,864...14,885,854
Ensembl chr12:14,880,864...14,885,857 		JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression ISO Isoproterenol results in increased expression of MGST1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259 		JBrowse link
G MIAT myocardial infarction associated transcript increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of MIAT
Lutein inhibits the reaction [Isoproterenol results in increased expression of MIAT]		 CTD PMID:34435724 NCBI chr22:26,646,429...26,676,478
Ensembl chr22:26,646,411...26,676,475 		JBrowse link
G MIB1 MIB E3 ubiquitin protein ligase 1 increases expression ISO Isoproterenol results in increased expression of MIB1 mRNA CTD PMID:20003209 NCBI chr18:21,704,916...21,870,953
Ensembl chr18:21,704,957...21,870,953 		JBrowse link
G MIR122 microRNA 122 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of MIR122 mRNA
xanthone inhibits the reaction [Isoproterenol results in increased expression of MIR122 mRNA]		 CTD PMID:36414029 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158 		JBrowse link
G MIR133A1 microRNA 133a-1 decreases expression ISO Isoproterenol results in decreased expression of MIR133A1 CTD PMID:19893015 NCBI chr18:21,825,698...21,825,785
Ensembl chr18:21,825,698...21,825,785 		JBrowse link
G MIR142 microRNA 142 increases expression ISO Isoproterenol results in increased expression of MIR142 mRNA CTD PMID:29355689 NCBI chr17:58,331,232...58,331,318
Ensembl chr17:58,331,232...58,331,318 		JBrowse link
G MIR145 microRNA 145 increases expression ISO isoprenaline increases expression of miRNA145 RNA in left ventricular myocardial tissues RGD PMID:35139769 RGD:155260312 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR155 microRNA 155 increases expression ISO Isoproterenol results in increased expression of MIR155 mRNA CTD PMID:29355689 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR19A microRNA 19a increases expression ISO Isoproterenol results in increased expression of MIR19A mRNA CTD PMID:29355689 NCBI chr13:91,350,891...91,350,972
Ensembl chr13:91,350,891...91,350,972 		JBrowse link
G MIR200A microRNA 200a decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of MIR200A mRNA
Lutein inhibits the reaction [Isoproterenol results in decreased expression of MIR200A mRNA]		 CTD PMID:34435724 NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952 		JBrowse link
G MIR208A microRNA 208a increases expression
decreases expression		 ISO Isoproterenol results in increased expression of MIR208A
Isoproterenol results in decreased expression of MIR208A mRNA		 CTD PMID:26454886 PMID:29355689 NCBI chr14:23,388,596...23,388,666
Ensembl chr14:23,388,596...23,388,666 		JBrowse link
G MIR208B microRNA 208b increases expression ISO Isoproterenol results in increased expression of MIR208B mRNA CTD PMID:29355689 NCBI chr14:23,417,987...23,418,063
Ensembl chr14:23,417,987...23,418,063 		JBrowse link
G MIR21 microRNA 21 increases expression ISO Isoproterenol results in increased expression of MIR21 mRNA CTD PMID:28526319 PMID:29355689 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR214 microRNA 214 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of MIR214 mRNA
MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:26692091 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MIR30E microRNA 30e decreases expression ISO Isoproterenol decreases expression of Mir30e mRNA in the heart RGD PMID:28777253 RGD:401827856 NCBI chr 1:40,754,355...40,754,446
Ensembl chr 1:40,754,355...40,754,446 		JBrowse link
G MIR384 microRNA 384 multiple interactions
decreases expression		 ISO MIR384 mRNA inhibits the reaction [Isoproterenol results in decreased expression of ALPK3 mRNA]
Isoproterenol results in decreased expression of MIR384 mRNA		 CTD PMID:35510648 NCBI chr  X:76,919,273...76,919,360
Ensembl chr  X:76,919,273...76,919,360 		JBrowse link
G MIX23 mitochondrial matrix import factor 23 decreases expression ISO Isoproterenol results in decreased expression of MIX23 mRNA CTD PMID:20003209 NCBI chr 3:122,359,591...122,383,231
Ensembl chr 3:122,359,591...122,383,231 		JBrowse link
G MKNK2 MAPK interacting serine/threonine kinase 2 increases expression ISO Isoproterenol results in increased expression of MKNK2 mRNA CTD PMID:20003209 NCBI chr19:2,037,471...2,051,244
Ensembl chr19:2,037,465...2,051,244 		JBrowse link
G MLF1 myeloid leukemia factor 1 decreases expression ISO Isoproterenol results in decreased expression of MLF1 mRNA CTD PMID:20003209 NCBI chr 3:158,571,194...158,606,456
Ensembl chr 3:158,571,163...158,607,252 		JBrowse link
G MLH1 mutL homolog 1 increases expression ISO Isoproterenol results in increased expression of MLH1 mRNA CTD PMID:21335049 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MMD monocyte to macrophage differentiation associated decreases expression ISO Isoproterenol results in decreased expression of MMD mRNA CTD PMID:20003209 NCBI chr17:55,392,622...55,421,835
Ensembl chr17:55,392,622...55,421,924 		JBrowse link
G MMP1 matrix metallopeptidase 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of MMP1
SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP1]		 CTD PMID:12883319 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP11 matrix metallopeptidase 11 increases expression ISO Isoproterenol results in increased expression of MMP11 mRNA CTD PMID:20003209 NCBI chr22:23,772,849...23,784,316
Ensembl chr22:23,768,226...23,784,316 		JBrowse link
G MMP14 matrix metallopeptidase 14 increases expression ISO Isoproterenol results in increased expression of MMP14 mRNA CTD PMID:21335049 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP15 matrix metallopeptidase 15 decreases expression ISO Isoproterenol results in decreased expression of MMP15 mRNA CTD PMID:20003209 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions
increases expression
increases activity		 ISO
EXP		 Doxycycline inhibits the reaction [Isoproterenol results in increased activity of MMP2]; Isoproterenol results in increased expression of and results in increased activity of MMP2 protein
geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP2 mRNA]
Isoproterenol results in increased expression of MMP2 mRNA; Isoproterenol results in increased expression of MMP2 protein		 CTD PMID:16327176 PMID:18089841 PMID:24929186 PMID:35608392 PMID:37016276 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP3 matrix metallopeptidase 3 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MMP3 mRNA]
SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP3]		 CTD PMID:12883319 PMID:18089841 PMID:20003209 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions
increases expression
increases activity		 EXP
ISO		 Propranolol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; geraniol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]
Isoproterenol results in increased activity of MMP9
Doxycycline inhibits the reaction [Isoproterenol results in increased activity of MMP9]		 CTD PMID:16574429 PMID:18089841 PMID:18594475 PMID:24929186 PMID:35608392 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MMRN1 multimerin 1 increases expression ISO Isoproterenol results in increased expression of MMRN1 mRNA CTD PMID:20003209 NCBI chr 4:89,879,511...89,954,614
Ensembl chr 4:89,879,532...89,954,629 		JBrowse link
G MOSPD2 motile sperm domain containing 2 increases expression ISO Isoproterenol results in increased expression of MOSPD2 mRNA CTD PMID:20003209 NCBI chr  X:14,873,421...14,922,327
Ensembl chr  X:14,873,421...14,922,327 		JBrowse link
G MPO myeloperoxidase multiple interactions
increases expression
increases activity		 ISO caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of MPO protein]; pyrvinium inhibits the reaction [Isoproterenol results in increased activity of MPO protein]; sodium thiosulfate inhibits the reaction [Isoproterenol results in increased activity of MPO protein]
Isoproterenol results in increased expression of MPO protein		 CTD PMID:20693123 PMID:32865837 PMID:35014750 PMID:35305975 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MPP7 MAGUK p55 scaffold protein 7 increases expression ISO Isoproterenol results in increased expression of MPP7 mRNA CTD PMID:20003209 NCBI chr10:28,050,993...28,335,203
Ensembl chr10:28,050,993...28,334,486 		JBrowse link
G MRC1 mannose receptor C-type 1 increases expression ISO Isoproterenol results in increased expression of MRC1 mRNA CTD PMID:20003209 NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164 		JBrowse link
G MRPL41 mitochondrial ribosomal protein L41 decreases expression ISO Isoproterenol results in decreased expression of MRPL41 mRNA CTD PMID:20003209 NCBI chr 9:137,551,879...137,552,555
Ensembl chr 9:137,551,879...137,552,555 		JBrowse link
G MRPL45 mitochondrial ribosomal protein L45 decreases expression ISO Isoproterenol results in decreased expression of MRPL45 mRNA CTD PMID:20003209 NCBI chr17:38,297,168...38,323,211
Ensembl chr17:38,297,023...38,323,217 		JBrowse link
G MSR1 macrophage scavenger receptor 1 increases expression ISO Isoproterenol results in increased expression of MSR1 mRNA CTD PMID:20003209 NCBI chr 8:16,107,881...16,192,651
Ensembl chr 8:16,107,878...16,567,490 		JBrowse link
G MT1X metallothionein 1X increases expression ISO Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209 PMID:21335049 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MT2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MTCH2 mitochondrial carrier 2 increases expression ISO Isoproterenol results in increased expression of MTCH2 mRNA CTD PMID:20003209 NCBI chr11:47,604,317...47,642,559
Ensembl chr11:47,617,315...47,642,607 		JBrowse link
G MTOR mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions		 ISO Isoproterenol results in increased phosphorylation of MTOR protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]]		 CTD PMID:17623046 PMID:25045214 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 decreases expression ISO Isoproterenol results in decreased expression of MTSS1 mRNA CTD PMID:20003209 NCBI chr 8:124,550,784...124,728,473
Ensembl chr 8:124,550,784...124,728,473 		JBrowse link
G MUSTN1 musculoskeletal, embryonic nuclear protein 1 increases expression ISO Isoproterenol results in increased expression of MUSTN1 mRNA CTD PMID:20003209 NCBI chr 3:52,833,121...52,835,019
Ensembl chr 3:52,833,114...52,835,019 		JBrowse link
G MYBPC3 myosin binding protein C3 multiple interactions
affects response to substance		 ISO
EXP		 MYBPC3 gene mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]
MYBPC3 protein affects the susceptibility to Isoproterenol
MYBPC3 mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]		 CTD PMID:22076249 PMID:23896226 NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression ISO Isoproterenol results in increased expression of MYC mRNA CTD PMID:20003209 PMID:20211217 PMID:21823215 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Isoproterenol results in decreased expression of MYCN mRNA CTD PMID:20003209 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of MYD88 mRNA; Isoproterenol results in increased expression of MYD88 protein
anethole inhibits the reaction [Isoproterenol results in increased expression of MYD88 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of MYD88 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of MYD88 mRNA]		 CTD PMID:24842192 PMID:35430261 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYH6 myosin heavy chain 6 multiple interactions
increases expression		 ISO plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH6 protein]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in decreased expression of MYH6 mRNA]]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of MYH6 protein] CTD PMID:31009642 PMID:37269933 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273 		JBrowse link
G MYH7 myosin heavy chain 7 multiple interactions
increases expression		 ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of MYH7 mRNA; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]
Isoproterenol results in increased expression of MYH7 mRNA; Isoproterenol results in increased expression of MYH7 protein
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]]		 CTD PMID:10710348 PMID:18089841 PMID:18851973 PMID:25045214 PMID:28816235 More... NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G MYH7B myosin heavy chain 7B decreases expression ISO Isoproterenol results in decreased expression of MYH7B mRNA CTD PMID:20003209 NCBI chr20:34,955,868...35,002,437
Ensembl chr20:34,955,810...35,002,437 		JBrowse link
G MYL1 myosin light chain 1 increases expression ISO Isoproterenol results in increased expression of MYL1 protein CTD PMID:19854236 NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174 		JBrowse link
G MYL3 myosin light chain 3 increases expression ISO Isoproterenol results in increased expression of MYL3 protein CTD PMID:24286936 NCBI chr 3:46,857,872...46,882,182
Ensembl chr 3:46,835,111...46,882,178 		JBrowse link
G MYLIP myosin regulatory light chain interacting protein increases expression ISO Isoproterenol results in increased expression of MYLIP mRNA CTD PMID:20003209 NCBI chr 6:16,129,086...16,163,887
Ensembl chr 6:16,129,086...16,148,248 		JBrowse link
G MYO5A myosin VA increases expression ISO Isoproterenol results in increased expression of MYO5A mRNA CTD PMID:20003209 NCBI chr15:52,307,283...52,529,050
Ensembl chr15:52,307,281...52,529,132 		JBrowse link
G MYOT myotilin increases expression ISO Isoproterenol results in increased expression of MYOT mRNA CTD PMID:20003209 NCBI chr 5:137,867,860...137,887,851
Ensembl chr 5:137,867,858...137,887,851 		JBrowse link
G MYRIP myosin VIIA and Rab interacting protein increases expression ISO Isoproterenol results in increased expression of MYRIP mRNA CTD PMID:20003209 NCBI chr 3:39,808,914...40,260,321
Ensembl chr 3:39,808,914...40,260,321 		JBrowse link
G N4BP2L1 NEDD4 binding protein 2 like 1 increases expression ISO Isoproterenol results in increased expression of N4BP2L1 mRNA CTD PMID:20003209 NCBI chr13:32,400,723...32,429,615
Ensembl chr13:32,400,723...32,428,311 		JBrowse link
G NAB1 NGFI-A binding protein 1 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB1 mRNA CTD PMID:10710348 NCBI chr 2:190,648,895...190,692,766
Ensembl chr 2:190,646,746...190,692,766 		JBrowse link
G NAB2 NGFI-A binding protein 2 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA] CTD PMID:10710348 NCBI chr12:57,089,114...57,095,476
Ensembl chr12:57,089,043...57,095,476 		JBrowse link
G NABP1 nucleic acid binding protein 1 decreases expression ISO Isoproterenol results in decreased expression of NABP1 mRNA CTD PMID:20003209 NCBI chr 2:191,678,136...191,686,943
Ensembl chr 2:191,678,068...191,741,097 		JBrowse link
G NAGLU N-acetyl-alpha-glucosaminidase increases activity
multiple interactions		 ISO Isoproterenol results in increased activity of NAGLU protein
Phytic Acid inhibits the reaction [Isoproterenol results in increased activity of NAGLU protein]		 CTD PMID:25560919 NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449 		JBrowse link
G NARS1 asparaginyl-tRNA synthetase 1 increases expression ISO Isoproterenol results in increased expression of NARS1 mRNA CTD PMID:21335049 NCBI chr18:57,600,656...57,621,836
Ensembl chr18:57,600,656...57,622,213 		JBrowse link
G NBN nibrin decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of NBN mRNA
Isoproterenol results in increased expression of NBN mRNA		 CTD PMID:21335049 NCBI chr 8:89,933,331...89,984,667
Ensembl chr 8:89,924,515...90,003,228 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 multiple interactions
increases expression		 ISO CPU0213 inhibits the reaction [Isoproterenol results in increased expression of NCF1 mRNA] CTD PMID:18594475 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 multiple interactions
increases expression		 ISO 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of NCF2 mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of NCF2 protein]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of NCF2 mRNA]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of NCF2 protein]
Isoproterenol results in increased expression of NCF2 mRNA; Isoproterenol results in increased expression of NCF2 protein		 CTD PMID:20723002 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NCSTN nicastrin increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of NCSTN mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NCSTN mRNA		 CTD PMID:30303030 NCBI chr 1:160,343,383...160,358,949
Ensembl chr 1:160,343,294...160,358,952 		JBrowse link
G NDRG1 N-myc downstream regulated 1 increases expression ISO Isoproterenol results in increased expression of NDRG1 mRNA CTD PMID:20003209 NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022 		JBrowse link
G NDUFA11 NADH:ubiquinone oxidoreductase subunit A11 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA11 mRNA CTD PMID:30303030 NCBI chr19:5,891,229...5,903,790
Ensembl chr19:5,891,276...5,904,006 		JBrowse link
G NDUFA2 NADH:ubiquinone oxidoreductase subunit A2 decreases expression ISO Isoproterenol results in decreased expression of NDUFA2 mRNA CTD PMID:30303030 NCBI chr 5:140,645,285...140,647,630
Ensembl chr 5:140,638,740...140,647,771 		JBrowse link
G NDUFB2 NADH:ubiquinone oxidoreductase subunit B2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB2 mRNA CTD PMID:30303030 NCBI chr 7:140,696,708...140,706,643
Ensembl chr 7:140,690,777...140,722,790 		JBrowse link
G NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB5 mRNA CTD PMID:30303030 NCBI chr 3:179,604,794...179,627,647
Ensembl chr 3:179,604,690...179,627,647 		JBrowse link
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB8 mRNA CTD PMID:30303030 NCBI chr10:100,523,729...100,529,923
Ensembl chr10:100,523,740...100,530,000 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS1 mRNA CTD PMID:30303030 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509 		JBrowse link
G NDUFS3 NADH:ubiquinone oxidoreductase core subunit S3 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS3 mRNA CTD PMID:30303030 NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS4 mRNA CTD PMID:30303030 NCBI chr 5:53,560,639...53,683,338
Ensembl chr 5:53,560,633...53,683,338 		JBrowse link
G NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS8 mRNA CTD PMID:30303030 NCBI chr11:68,030,681...68,036,644
Ensembl chr11:68,030,617...68,036,644 		JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV1 mRNA CTD PMID:30303030 NCBI chr11:67,606,936...67,612,554
Ensembl chr11:67,605,653...67,612,554 		JBrowse link
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV2 mRNA CTD PMID:30303030 NCBI chr18:9,102,699...9,134,341
Ensembl chr18:9,102,630...9,134,345 		JBrowse link
G NEB nebulin increases expression ISO Isoproterenol results in increased expression of NEB mRNA CTD PMID:20003209 NCBI chr 2:151,485,339...151,734,476
Ensembl chr 2:151,485,336...151,734,487 		JBrowse link
G NES nestin decreases expression ISO Isoproterenol results in decreased expression of NES mRNA CTD PMID:20003209 NCBI chr 1:156,668,763...156,677,407
Ensembl chr 1:156,668,763...156,677,407 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 affects localization
multiple interactions		 ISO Isoproterenol affects the localization of NFATC1 protein
Cyclosporine inhibits the reaction [Isoproterenol affects the localization of NFATC1 protein]; Isoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]		 CTD PMID:11435416 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases expression
increases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of NFE2L2 mRNA; Isoproterenol results in decreased expression of NFE2L2 protein
Isoproterenol results in increased expression of NFE2L2 mRNA; Isoproterenol results in increased expression of NFE2L2 protein
[erdosteine co-treated with Isoproterenol] results in increased expression of NFE2L2 protein; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFE2L2 mRNA; anethole promotes the reaction [Isoproterenol results in increased expression of NFE2L2 mRNA]; anethole promotes the reaction [Isoproterenol results in increased expression of NFE2L2 protein]; Lutein inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA]		 CTD PMID:28266775 PMID:30303030 PMID:32007421 PMID:33210414 PMID:34435724 More... NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFIC nuclear factor I C decreases expression ISO Isoproterenol results in decreased expression of NFIC mRNA CTD PMID:20003209 NCBI chr19:3,359,630...3,469,217
Ensembl chr19:3,314,403...3,469,217 		JBrowse link
G NFIL3 nuclear factor, interleukin 3 regulated increases expression ISO Isoproterenol results in increased expression of NFIL3 mRNA CTD PMID:20003209 NCBI chr 9:91,409,045...91,483,497
Ensembl chr 9:91,409,045...91,423,832 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
increases activity		 ISO Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]
Isoproterenol results in increased expression of NFKB1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKB1 mRNA
Isoproterenol results in increased activity of NFKB1 protein		 CTD PMID:15178407 PMID:18487443 PMID:30303030 PMID:35014750 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases expression
increases degradation
multiple interactions
decreases expression		 ISO Isoproterenol results in increased expression of NFKBIA mRNA
Isoproterenol results in increased degradation of NFKBIA protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKBIA mRNA; Isoproterenol promotes the reaction [G3BP2 protein binds to NFKBIA protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased degradation of NFKBIA protein]
Isoproterenol results in decreased expression of NFKBIA mRNA
Isoproterenol results in decreased expression of NFKBIA protein
Isoproterenol results in increased phosphorylation of and results in increased degradation of NFKBIA protein		 CTD PMID:15178407 PMID:18487443 PMID:20003209 PMID:21335049 PMID:25045214 More... NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NFKBIZ NFKB inhibitor zeta increases expression ISO Isoproterenol results in increased expression of NFKBIZ mRNA CTD PMID:20003209 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022 		JBrowse link
G NGF nerve growth factor increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of NGF mRNA
[Isoproterenol results in increased abundance of Cyclic AMP] which results in increased expression of NGF mRNA; Propranolol inhibits the reaction [Isoproterenol results in increased expression of NGF mRNA]		 CTD PMID:2174743 PMID:2853697 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NHERF4 NHERF family PDZ scaffold protein 4 decreases expression ISO Isoproterenol results in decreased expression of NHERF4 mRNA CTD PMID:20003209 NCBI chr11:119,185,475...119,190,213
Ensembl chr11:119,185,457...119,190,223 		JBrowse link
G NINJ1 ninjurin 1 increases expression ISO Isoproterenol results in increased expression of NINJ1 mRNA CTD PMID:20003209 NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251 		JBrowse link
G NKIRAS2 NFKB inhibitor interacting Ras like 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NKIRAS2 mRNA CTD PMID:30303030 NCBI chr17:42,017,576...42,025,641
Ensembl chr17:42,011,382...42,025,644 		JBrowse link
G NKX2-5 NK2 homeobox 5 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NKX2-5 mRNA CTD PMID:10710348 NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311 		JBrowse link
G NME6 NME/NM23 nucleoside diphosphate kinase 6 increases expression ISO Isoproterenol results in increased expression of NME6 mRNA CTD PMID:21335049 NCBI chr 3:48,288,402...48,301,367
Ensembl chr 3:48,290,722...48,301,685 		JBrowse link
G NMRK2 nicotinamide riboside kinase 2 decreases expression ISO Isoproterenol results in decreased expression of NMRK2 mRNA CTD PMID:20003209 NCBI chr19:3,933,069...3,942,416
Ensembl chr19:3,933,069...3,942,416 		JBrowse link
G NOCT nocturnin increases expression ISO Isoproterenol results in increased expression of NOCT mRNA CTD PMID:20003209 NCBI chr 4:139,015,781...139,045,939
Ensembl chr 4:139,015,781...139,045,939 		JBrowse link
G NOL3 nucleolar protein 3 decreases phosphorylation ISO Isoproterenol results in decreased phosphorylation of NOL3 protein CTD PMID:19001025 NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737 		JBrowse link
G NOS1 nitric oxide synthase 1 increases expression
multiple interactions
decreases expression		 ISO Isoproterenol results in increased expression of NOS1 protein
thymoquinone inhibits the reaction [Isoproterenol results in decreased expression of NOS1 protein]		 CTD PMID:16702995 PMID:35940283 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression
multiple interactions
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of NOS2 mRNA
[Isoproterenol results in increased expression of NOS2] which results in increased chemical synthesis of Nitric Oxide; Apigenin inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; caryophyllene inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; natakalim inhibits the reaction [[Isoproterenol results in increased expression of NOS2] which results in increased chemical synthesis of Nitric Oxide]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NOS2]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of NOS2 mRNA]
Isoproterenol results in increased expression of NOS2; Isoproterenol results in increased expression of NOS2 mRNA; Isoproterenol results in increased expression of NOS2 protein		 CTD PMID:18594475 PMID:18816294 PMID:19168511 PMID:19466570 PMID:24286936 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
increases expression
decreases expression
affects response to substance		 ISO 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol affects the expression of NOS3 mRNA]; 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol affects the expression of NOS3 protein]; 5-Methoxypsoralen inhibits the reaction [Isoproterenol results in decreased phosphorylation of NOS3 protein]; [Isoproterenol co-treated with Caffeine] results in decreased expression of NOS3 mRNA; caryophyllene inhibits the reaction [Isoproterenol results in decreased expression of NOS3 protein]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in decreased expression of NOS3 mRNA]; natakalim inhibits the reaction [Isoproterenol results in decreased expression of NOS3 mRNA]; thymoquinone inhibits the reaction [Isoproterenol results in increased expression of NOS3 protein]
Isoproterenol results in increased expression of NOS3 mRNA; Isoproterenol results in increased expression of NOS3 protein
Isoproterenol results in decreased expression of NOS3 mRNA; Isoproterenol results in decreased expression of NOS3 protein
NOS3 protein affects the susceptibility to Isoproterenol
NOS3 inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]		 CTD PMID:12224825 PMID:16702995 PMID:17403420 PMID:17996136 PMID:18816294 More... NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOTCH1 notch receptor 1 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of NOTCH1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of NOTCH1 mRNA		 CTD PMID:30303030 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH4 notch receptor 4 increases expression ISO Isoproterenol results in increased expression of NOTCH4 mRNA CTD PMID:20003209 NCBI chr 6:32,194,843...32,224,067
Ensembl chr 6:32,194,843...32,224,067 		JBrowse link
G NOX4 NADPH oxidase 4 multiple interactions
increases expression		 ISO bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NOX4 mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NOX4 protein]; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of NOX4 mRNA]
Isoproterenol results in increased expression of NOX4 mRNA; Isoproterenol results in increased expression of NOX4 protein		 CTD PMID:18089841 PMID:20003209 PMID:37528096 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPM1 nucleophosmin 1 decreases expression ISO Isoproterenol results in decreased expression of NPM1 mRNA CTD PMID:21335049 NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810 		JBrowse link
G NPM3 nucleophosmin/nucleoplasmin 3 decreases expression ISO Isoproterenol results in decreased expression of NPM3 mRNA CTD PMID:20003209 NCBI chr10:101,781,325...101,783,446
Ensembl chr10:101,781,325...101,783,446 		JBrowse link
G NPPA natriuretic peptide A multiple interactions
increases expression
decreases secretion
decreases expression		 ISO
EXP		 [Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; NOS3 inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes
Isoproterenol results in decreased secretion of NPPA protein
Isoproterenol results in increased expression of NPPA mRNA; Isoproterenol results in increased expression of NPPA protein
Isoproterenol results in decreased expression of NPPA protein
ADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]; Atorvastatin inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA protein]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; manidipine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; thymoquinone inhibits the reaction [Isoproterenol results in decreased secretion of NPPA protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]		 CTD
RGD		 PMID:8077211 PMID:9043801 PMID:9559417 PMID:10710348 PMID:10888249 More... RGD:11526363 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B multiple interactions
increases expression
decreases secretion		 ISO
EXP		 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB protein]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; thymoquinone inhibits the reaction [Isoproterenol results in decreased secretion of NPPB protein modified form]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]
isoprenaline increases expression of mRNA in neonatal rat cardiomyocytes
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; swietenine inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]
Isoproterenol results in increased expression of NPPB mRNA; Isoproterenol results in increased expression of NPPB protein		 CTD
RGD		 PMID:9043801 PMID:11804996 PMID:18806606 PMID:25045214 PMID:27890915 More... RGD:11526363 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases expression		 ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NQO1 mRNA
Isoproterenol results in decreased expression of NQO1 mRNA		 CTD PMID:30303030 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 decreases expression ISO Isoproterenol results in decreased expression of NQO2 mRNA CTD PMID:21335049 NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of NR1H4 mRNA
Isoproterenol results in increased expression of NR1H4 mRNA		 CTD PMID:24286936 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 decreases expression ISO Isoproterenol results in decreased expression of NR4A1 mRNA CTD PMID:20003209 NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 increases expression ISO Isoproterenol results in increased expression of NR4A3 mRNA CTD PMID:34601065 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
G NSMAF neutral sphingomyelinase activation associated factor multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of NSMAF mRNA CTD PMID:30303030 NCBI chr 8:58,583,504...58,659,853
Ensembl chr 8:58,583,508...58,659,853 		JBrowse link
G NTF3 neurotrophin 3 decreases expression ISO Isoproterenol results in decreased expression of NTF3 mRNA CTD PMID:20003209 NCBI chr12:5,430,332...5,495,299
Ensembl chr12:5,432,108...5,521,536 		JBrowse link
G NUCB2 nucleobindin 2 increases expression ISO Isoproterenol results in increased expression of NUCB2 mRNA CTD PMID:21823215 NCBI chr11:17,276,739...17,349,980
Ensembl chr11:17,208,153...17,349,980 		JBrowse link
G NXT2 nuclear transport factor 2 like export factor 2 increases expression ISO Isoproterenol results in increased expression of NXT2 mRNA CTD PMID:20003209 NCBI chr  X:109,535,824...109,544,698
Ensembl chr  X:109,535,781...109,544,698 		JBrowse link
G OAZ2 ornithine decarboxylase antizyme 2 decreases expression ISO Isoproterenol results in decreased expression of OAZ2 mRNA CTD PMID:20003209 NCBI chr15:64,687,574...64,703,281
Ensembl chr15:64,687,573...64,703,281 		JBrowse link
G ODC1 ornithine decarboxylase 1 multiple interactions
increases activity		 ISO Propranolol inhibits the reaction [Isoproterenol results in increased activity of ODC1 protein] CTD PMID:6284819 PMID:10354516 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327 		JBrowse link
G OGA O-GlcNAcase increases expression ISO Isoproterenol results in increased expression of OGA mRNA CTD PMID:20003209 NCBI chr10:101,784,450...101,818,444
Ensembl chr10:101,784,443...101,818,465 		JBrowse link
G OGDH oxoglutarate dehydrogenase decreases expression
decreases activity
multiple interactions		 ISO Isoproterenol results in decreased expression of OGDH mRNA
Isoproterenol results in decreased activity of OGDH protein
naringin inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased expression of OGDH mRNA]; sinapinic acid inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of OGDH protein]		 CTD PMID:9753871 PMID:17182065 PMID:17994577 PMID:26721194 PMID:32627257 NCBI chr 7:44,606,627...44,709,066
Ensembl chr 7:44,606,572...44,709,066 		JBrowse link
G OMD osteomodulin increases expression ISO Isoproterenol results in increased expression of OMD mRNA CTD PMID:20003209 NCBI chr 9:92,412,380...92,424,471
Ensembl chr 9:92,412,380...92,424,471 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase decreases expression ISO Isoproterenol results in decreased expression of OPA1 protein CTD PMID:27491814 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G OSMR oncostatin M receptor multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of OSMR mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596 		JBrowse link
G OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 decreases expression ISO Isoproterenol results in decreased expression of OTUB1 mRNA CTD PMID:20003209 NCBI chr11:63,986,438...63,998,412
Ensembl chr11:63,985,853...64,001,811 		JBrowse link
G P3H2 prolyl 3-hydroxylase 2 increases expression ISO Isoproterenol results in increased expression of P3H2 mRNA CTD PMID:20003209 NCBI chr 3:189,956,728...190,122,278
Ensembl chr 3:189,956,728...190,122,437 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta increases expression ISO Isoproterenol results in increased expression of P4HB mRNA CTD PMID:21823215 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856 		JBrowse link
G PACRG parkin coregulated increases expression ISO Isoproterenol results in increased expression of PACRG mRNA CTD PMID:20003209 NCBI chr 6:162,727,132...163,315,500
Ensembl chr 6:162,727,132...163,315,500 		JBrowse link
G PALLD palladin, cytoskeletal associated protein decreases expression ISO Isoproterenol results in decreased expression of PALLD mRNA CTD PMID:20003209 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression ISO Isoproterenol results in increased expression of PAPSS2 mRNA CTD PMID:20003209 NCBI chr10:87,659,878...87,747,705
Ensembl chr10:87,659,613...87,747,705 		JBrowse link
G PAQR9 progestin and adipoQ receptor family member 9 decreases expression ISO Isoproterenol results in decreased expression of PAQR9 mRNA CTD PMID:20003209 NCBI chr 3:142,949,164...142,964,008
Ensembl chr 3:142,949,164...142,963,674 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 decreases expression
multiple interactions
increases expression
increases cleavage		 EXP
ISO		 Isoproterenol results in decreased expression of PARP1 protein
erdosteine affects the reaction [Isoproterenol results in increased expression of PARP1 protein]
BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein]		 CTD PMID:29438734 PMID:31712309 PMID:33210414 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression		 ISO [Isoproterenol co-treated with rosiglitazone] results in increased expression of PCK1 mRNA; Dexamethasone inhibits the reaction [Isoproterenol results in increased expression of PCK1 mRNA] CTD PMID:9518257 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121 		JBrowse link
G PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 increases expression ISO Isoproterenol results in increased expression of PCMTD2 mRNA CTD PMID:20003209 NCBI chr20:64,255,748...64,276,226
Ensembl chr20:64,255,695...64,304,820 		JBrowse link
G PDE3B phosphodiesterase 3B multiple interactions ISO [PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein] CTD PMID:19167487 NCBI chr11:14,643,804...14,872,044
Ensembl chr11:14,643,804...14,872,044 		JBrowse link
G PDE4A phosphodiesterase 4A decreases expression ISO Isoproterenol results in decreased expression of PDE4A mRNA CTD PMID:20003209 NCBI chr19:10,416,773...10,469,631
Ensembl chr19:10,416,773...10,469,630 		JBrowse link
G PDE7A phosphodiesterase 7A increases expression ISO Isoproterenol results in increased expression of PDE7A mRNA CTD PMID:20003209 NCBI chr 8:65,714,334...65,842,064
Ensembl chr 8:65,714,334...65,842,322 		JBrowse link
G PDGFD platelet derived growth factor D increases expression ISO Isoproterenol results in increased expression of PDGFD mRNA CTD PMID:20003209 NCBI chr11:103,907,189...104,164,147
Ensembl chr11:103,907,189...104,164,379 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 increases expression ISO Isoproterenol results in increased expression of PDIA4 mRNA CTD PMID:21335049 PMID:21823215 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 increases expression ISO Isoproterenol results in increased expression of PDIA6 mRNA CTD PMID:21823215 NCBI chr 2:10,783,391...10,837,712
Ensembl chr 2:10,783,391...10,837,977 		JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 increases expression ISO Isoproterenol results in increased expression of PDK1 mRNA CTD PMID:20003209 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669 		JBrowse link
G PDXDC1 pyridoxal dependent decarboxylase domain containing 1 decreases expression ISO Isoproterenol results in decreased expression of PDXDC1 mRNA CTD PMID:20003209 NCBI chr16:14,974,735...15,153,218
Ensembl chr16:14,974,591...15,139,339 		JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 multiple interactions
decreases expression		 EXP
ISO		 PEBP1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of PEBP1 mRNA
Isoproterenol results in decreased expression of PEBP1 mRNA		 CTD PMID:26670611 PMID:30303030 NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584 		JBrowse link
G PECR peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PECR mRNA CTD PMID:30303030 NCBI chr 2:216,029,088...216,081,809
Ensembl chr 2:215,996,329...216,082,955 		JBrowse link
G PEG3 paternally expressed 3 increases expression ISO Isoproterenol results in increased expression of PEG3 mRNA CTD PMID:20003209 NCBI chr19:56,810,082...56,840,726
Ensembl chr19:56,810,077...56,840,728 		JBrowse link
G PENK proenkephalin multiple interactions
increases expression		 ISO Metoprolol inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA]; Serotonin inhibits the reaction [Isoproterenol results in increased expression of PENK mRNA] CTD PMID:1363325 NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671 		JBrowse link
G PER3 period circadian regulator 3 decreases expression ISO Isoproterenol results in decreased expression of PER3 mRNA CTD PMID:20003209 NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177 		JBrowse link
G PEX12 peroxisomal biogenesis factor 12 increases expression ISO Isoproterenol results in increased expression of PEX12 mRNA CTD PMID:20003209 NCBI chr17:35,574,795...35,578,571
Ensembl chr17:35,574,795...35,578,863 		JBrowse link
G PEX2 peroxisomal biogenesis factor 2 increases expression ISO Isoproterenol results in increased expression of PEX2 mRNA CTD PMID:21335049 NCBI chr 8:76,980,258...77,001,044
Ensembl chr 8:76,980,258...77,001,044 		JBrowse link
G PGM2L1 phosphoglucomutase 2 like 1 increases expression ISO Isoproterenol results in increased expression of PGM2L1 mRNA CTD PMID:20003209 NCBI chr11:74,330,316...74,398,433
Ensembl chr11:74,330,316...74,398,433 		JBrowse link
G PHF3 PHD finger protein 3 increases expression ISO Isoproterenol results in increased expression of PHF3 mRNA CTD PMID:20003209 NCBI chr 6:63,635,802...63,726,011
Ensembl chr 6:63,635,802...63,779,336 		JBrowse link
G PHKA1 phosphorylase kinase regulatory subunit alpha 1 increases expression ISO Isoproterenol results in increased expression of PHKA1 mRNA CTD PMID:20003209 NCBI chr  X:72,578,814...72,714,306
Ensembl chr  X:72,578,814...72,714,319 		JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 decreases expression ISO Isoproterenol results in decreased expression of PHLDA1 mRNA CTD PMID:20003209 NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776 		JBrowse link
G PHLDA3 pleckstrin homology like domain family A member 3 decreases expression ISO Isoproterenol results in decreased expression of PHLDA3 mRNA CTD PMID:21335049 NCBI chr 1:201,464,278...201,469,188
Ensembl chr 1:201,464,278...201,469,237 		JBrowse link
G PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 increases expression ISO Isoproterenol results in increased expression of PHYHD1 mRNA CTD PMID:20003209 NCBI chr 9:128,920,982...128,942,041
Ensembl chr 9:128,920,966...128,942,041 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein increases expression ISO Isoproterenol results in increased expression of PICALM mRNA CTD PMID:20003209 NCBI chr11:85,957,175...86,069,860
Ensembl chr11:85,957,175...86,069,882 		JBrowse link
G PIGA phosphatidylinositol glycan anchor biosynthesis class A increases expression ISO Isoproterenol results in increased expression of PIGA mRNA CTD PMID:21823215 NCBI chr  X:15,319,451...15,335,554
Ensembl chr  X:15,319,452...15,335,554 		JBrowse link
G PIGB phosphatidylinositol glycan anchor biosynthesis class B decreases expression ISO Isoproterenol results in decreased expression of PIGB mRNA CTD PMID:21823215 NCBI chr15:55,319,222...55,355,648
Ensembl chr15:55,318,960...55,355,648 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions
increases activity		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased activity of PIK3CG protein]; wortmannin inhibits the reaction [Isoproterenol results in increased activity of PIK3CG protein] CTD PMID:15178407 NCBI chr 7:106,865,282...106,908,980
Ensembl chr 7:106,865,278...106,908,980 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO Isoproterenol results in increased expression of PIK3R1 mRNA CTD PMID:20003209 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIM3 Pim-3 proto-oncogene, serine/threonine kinase increases expression ISO Isoproterenol results in increased expression of PIM3 mRNA CTD PMID:20003209 NCBI chr22:49,960,772...49,964,072
Ensembl chr22:49,960,768...49,964,072 		JBrowse link
G PIR pirin increases expression ISO Isoproterenol results in increased expression of PIR mRNA CTD PMID:20003209 NCBI chr  X:15,384,799...15,493,333
Ensembl chr  X:15,384,799...15,493,564 		JBrowse link
G PITPNC1 phosphatidylinositol transfer protein cytoplasmic 1 decreases expression ISO Isoproterenol results in decreased expression of PITPNC1 mRNA CTD PMID:20003209 NCBI chr17:67,377,281...67,697,256
Ensembl chr17:67,377,281...67,697,256 		JBrowse link
G PLA2G4A phospholipase A2 group IVA increases expression ISO Isoproterenol results in increased expression of PLA2G4A mRNA CTD PMID:20211217 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLA2G7 phospholipase A2 group VII multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of PLA2G7 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 6:46,704,201...46,735,721
Ensembl chr 6:46,704,201...46,735,693 		JBrowse link
G PLAGL1 PLAG1 like zinc finger 1 increases expression ISO Isoproterenol results in increased expression of PLAGL1 mRNA CTD PMID:20003209 NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599 		JBrowse link
G PLAT plasminogen activator, tissue type multiple interactions
increases secretion
increases expression		 ISO Cycloheximide promotes the reaction [Isoproterenol results in increased expression of PLAT mRNA]
Isoproterenol results in increased secretion of PLAT protein		 CTD PMID:2477232 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLAU plasminogen activator, urokinase increases expression ISO Isoproterenol results in increased expression of PLAU mRNA CTD PMID:20211217 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PLCB4 phospholipase C beta 4 increases expression ISO Isoproterenol results in increased expression of PLCB4 mRNA CTD PMID:20003209 NCBI chr20:9,068,678...9,480,808
Ensembl chr20:9,067,825...9,504,593 		JBrowse link
G PLD1 phospholipase D1 increases expression ISO Isoproterenol results in increased expression of PLD1 mRNA CTD PMID:20003209 NCBI chr 3:171,600,404...171,810,483
Ensembl chr 3:171,600,404...171,810,950 		JBrowse link
G PLN phospholamban multiple interactions
decreases phosphorylation
increases phosphorylation		 ISO astragaloside A inhibits the reaction [Isoproterenol results in decreased phosphorylation of PLN protein]; candesartan inhibits the reaction [Isoproterenol results in decreased phosphorylation of PLN protein]; Isoproterenol results in decreased expression of and results in decreased phosphorylation of PLN protein; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased phosphorylation of PLN protein]
Isoproterenol results in increased phosphorylation of PLN protein		 CTD PMID:10997724 PMID:16723803 PMID:17509559 PMID:21268078 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716 		JBrowse link
G PLXND1 plexin D1 decreases expression ISO Isoproterenol results in decreased expression of PLXND1 mRNA CTD PMID:20003209 NCBI chr 3:129,555,214...129,606,676
Ensembl chr 3:129,555,214...129,606,676 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP Isoproterenol results in increased expression of PMAIP1 mRNA CTD PMID:24286936 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G PNLIP pancreatic lipase multiple interactions
increases activity		 ISO oleuropein inhibits the reaction [Isoproterenol results in increased activity of PNLIP protein] CTD PMID:26056852 NCBI chr10:116,545,931...116,567,855
Ensembl chr10:116,545,931...116,567,855 		JBrowse link
G PNP purine nucleoside phosphorylase increases expression ISO Isoproterenol results in increased expression of PNP mRNA CTD PMID:20003209 PMID:21335049 NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094 		JBrowse link
G PNPLA7 patatin like phospholipase domain containing 7 increases expression ISO Isoproterenol results in increased expression of PNPLA7 mRNA CTD PMID:20003209 NCBI chr 9:137,459,952...137,550,402
Ensembl chr 9:137,459,952...137,550,402 		JBrowse link
G POMC proopiomelanocortin increases secretion ISO Isoproterenol results in increased secretion of POMC protein alternative form CTD PMID:10898105 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G POPDC3 popeye domain containing 3 increases expression ISO Isoproterenol results in increased expression of POPDC3 mRNA CTD PMID:20003209 NCBI chr 6:105,157,900...105,180,014
Ensembl chr 6:105,157,900...105,180,014 		JBrowse link
G POSTN periostin increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of POSTN mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADL mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADM mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADS mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACADVL mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ACSL1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AKT1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1A mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5F1D mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5MC1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP5PO mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ATP6AP2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of AZI2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of BAG4 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of BIRC2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CASP7 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CDC37 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CHUK mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of COPS3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT1A mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CPT2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of CUL1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of DMAC2L mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ELP1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of GLG1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of GPX1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of HADHA mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of JUN mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KCNQ1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KEAP1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of KPNA6 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of LRPPRC mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP2K4 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of MAP3K2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NCSTN mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA10L1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFA11 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFB8 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS4 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFS8 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NDUFV2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFE2L2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKB1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NFKBIA mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NKIRAS2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NOTCH1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NQO1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of NSMAF mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PEBP1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PECR mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PRKACA mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMA7 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB8 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC6 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD11 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD13 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD5 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of SLC25A20 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of SOD2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of TBK1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of TXNRD2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of UBA1 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of USP2 mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of XDH mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of YWHAG mRNA; [Isoproterenol co-treated with POSTN protein] results in decreased expression of ZFAND5 mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5ME mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of ATP5PD mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of BCL2 mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of DAP mRNA; [Isoproterenol co-treated with POSTN protein] results in increased expression of TNF mRNA		 CTD PMID:20003209 PMID:30303030 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of PPARA mRNA
Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA protein]]
Isoproterenol results in decreased expression of PPARA mRNA; Isoproterenol results in decreased expression of PPARA protein
osthol inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in decreased expression of MYH6 mRNA]]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; PPARA protein promotes the reaction [celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]		 CTD PMID:21854795 PMID:24286936 PMID:25045214 PMID:37269933 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of PPARG mRNA
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; [Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of PPARG protein]
Isoproterenol results in decreased expression of PPARG mRNA; Isoproterenol results in decreased expression of PPARG protein
osthol inhibits the reaction [Isoproterenol results in decreased expression of PPARG mRNA]		 CTD PMID:21854795 PMID:24286936 PMID:24954035 PMID:30623541 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression
multiple interactions
decreases expression		 ISO Isoproterenol results in increased expression of PPARGC1A mRNA
Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A protein]]
Isoproterenol results in decreased expression of PPARGC1A mRNA; Isoproterenol results in decreased expression of PPARGC1A protein		 CTD PMID:19808358 PMID:25045214 PMID:34601065 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPARGC1B PPARG coactivator 1 beta decreases expression ISO Isoproterenol results in decreased expression of PPARGC1B mRNA CTD PMID:20003209 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022 		JBrowse link
G PPFIBP1 PPFIA binding protein 1 increases expression ISO Isoproterenol results in increased expression of PPFIBP1 mRNA CTD PMID:20003209 NCBI chr12:27,524,206...27,695,564
Ensembl chr12:27,523,431...27,695,564 		JBrowse link
G PPFIBP2 PPFIA binding protein 2 increases expression ISO Isoproterenol results in increased expression of PPFIBP2 mRNA CTD PMID:20003209 NCBI chr11:7,513,999...7,667,304
Ensembl chr11:7,513,298...7,657,127 		JBrowse link
G PPIF peptidylprolyl isomerase F decreases expression ISO Isoproterenol results in decreased expression of PPIF mRNA CTD PMID:20003209 NCBI chr10:79,347,469...79,355,334
Ensembl chr10:79,347,469...79,355,334 		JBrowse link
G PPIL6 peptidylprolyl isomerase like 6 increases expression ISO Isoproterenol results in increased expression of PPIL6 mRNA CTD PMID:20003209 NCBI chr 6:109,390,215...109,441,171
Ensembl chr 6:109,390,215...109,441,171 		JBrowse link
G PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 increases expression ISO Isoproterenol results in increased expression of PPIP5K2 mRNA CTD PMID:20003209 NCBI chr 5:103,120,301...103,212,799
Ensembl chr 5:103,120,149...103,212,799 		JBrowse link
G PPM1E protein phosphatase, Mg2+/Mn2+ dependent 1E increases expression ISO Isoproterenol results in increased expression of PPM1E mRNA CTD PMID:20003209 NCBI chr17:58,755,854...58,985,179
Ensembl chr17:58,755,854...58,985,179 		JBrowse link
G PPM1J protein phosphatase, Mg2+/Mn2+ dependent 1J decreases expression ISO Isoproterenol results in decreased expression of PPM1J mRNA CTD PMID:20003209 NCBI chr 1:112,709,998...112,715,332
Ensembl chr 1:112,709,994...112,715,332 		JBrowse link
G PPP1R14C protein phosphatase 1 regulatory inhibitor subunit 14C decreases expression ISO Isoproterenol results in decreased expression of PPP1R14C mRNA CTD PMID:20003209 NCBI chr 6:150,143,044...150,250,392
Ensembl chr 6:150,143,044...150,250,392 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A increases expression ISO Isoproterenol results in increased expression of PPP1R15A mRNA CTD PMID:20003209 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha affects response to substance ISO PPP2CA protein affects the susceptibility to Isoproterenol CTD PMID:15247211 NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,194,035...134,226,073 		JBrowse link
G PRDX1 peroxiredoxin 1 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of PRDX1 mRNA; Isoproterenol results in decreased expression of PRDX1 protein
geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 mRNA]; geraniol inhibits the reaction [Isoproterenol results in decreased expression of PRDX1 protein]		 CTD PMID:35608392 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732 		JBrowse link
G PRG4 proteoglycan 4 increases expression ISO Isoproterenol results in increased expression of PRG4 mRNA CTD PMID:20003209 NCBI chr 1:186,296,273...186,314,567
Ensembl chr 1:186,296,279...186,314,567 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases phosphorylation		 ISO Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein; orlistat inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein]
Isoproterenol results in increased phosphorylation of PRKAA1 protein
[PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; OPC 3911 inhibits the reaction [INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]]; orlistat inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]		 CTD PMID:18390901 PMID:19167487 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
decreases expression		 ISO xanthone inhibits the reaction [Isoproterenol results in decreased expression of PRKAA2 mRNA] CTD PMID:36414029 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PRKACA mRNA CTD PMID:30303030 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of PRKAR2B protein
natakalim inhibits the reaction [Isoproterenol results in decreased expression of PRKAR2B protein]		 CTD PMID:27890915 NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,705...107,161,811 		JBrowse link
G PRKCA protein kinase C alpha increases expression ISO Isoproterenol results in increased expression of PRKCA mRNA; Isoproterenol results in increased expression of PRKCA protein CTD PMID:12775975 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PRKCB protein kinase C beta decreases expression ISO Isoproterenol results in decreased expression of PRKCB mRNA CTD PMID:21335049 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRKCD protein kinase C delta multiple interactions
increases phosphorylation
increases expression		 ISO 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKCD protein]
Isoproterenol results in increased expression of PRKCD mRNA; Isoproterenol results in increased expression of PRKCD protein		 CTD PMID:12775975 PMID:16716347 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKCE protein kinase C epsilon multiple interactions
increases expression
increases phosphorylation		 ISO 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKCE protein]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein modified form]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein]
Isoproterenol results in increased expression of PRKCE mRNA; Isoproterenol results in increased expression of PRKCE protein; Isoproterenol results in increased expression of PRKCE protein modified form		 CTD PMID:12775975 PMID:16716347 PMID:20307649 PMID:20723002 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PRL prolactin increases expression ISO Isoproterenol results in increased expression of PRL CTD PMID:1208595 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 decreases expression ISO Isoproterenol results in decreased expression of PRMT1 mRNA CTD PMID:20003209 NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029 		JBrowse link
G PRND prion like protein doppel decreases expression ISO Isoproterenol results in decreased expression of PRND mRNA CTD PMID:20003209 NCBI chr20:4,721,909...4,728,460
Ensembl chr20:4,721,909...4,728,460 		JBrowse link
G PRODH proline dehydrogenase 1 decreases expression ISO Isoproterenol results in decreased expression of PRODH mRNA CTD PMID:21335049 NCBI chr22:18,912,781...18,936,553
Ensembl chr22:18,912,777...18,936,553 		JBrowse link
G PROX1 prospero homeobox 1 decreases expression ISO Isoproterenol results in decreased expression of PROX1 mRNA CTD PMID:20003209 NCBI chr 1:213,983,151...214,041,510
Ensembl chr 1:213,983,181...214,041,510 		JBrowse link
G PSEN1 presenilin 1 increases expression ISO Isoproterenol results in increased expression of PSEN1 mRNA CTD PMID:21335049 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSIP1 PC4 and SRSF1 interacting protein 1 increases expression ISO Isoproterenol results in increased expression of PSIP1 mRNA CTD PMID:20003209 NCBI chr 9:15,464,066...15,510,970
Ensembl chr 9:15,464,066...15,510,995 		JBrowse link
G PSMA7 proteasome 20S subunit alpha 7 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMA7 mRNA CTD PMID:30303030 NCBI chr20:62,136,733...62,143,394
Ensembl chr20:62,136,733...62,143,440 		JBrowse link
G PSMB1 proteasome 20S subunit beta 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB1 mRNA CTD PMID:30303030 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307 		JBrowse link
G PSMB5 proteasome 20S subunit beta 5 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB5 mRNA CTD PMID:30303030 NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230 		JBrowse link
G PSMB8 proteasome 20S subunit beta 8 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of PSMB8 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMB8 mRNA		 CTD PMID:30303030 NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679 		JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC5 mRNA CTD PMID:30303030 NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMC6 mRNA CTD PMID:30303030 NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590 		JBrowse link
G PSMD1 proteasome 26S subunit, non-ATPase 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD1 mRNA CTD PMID:30303030 NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,845...231,173,116 		JBrowse link
G PSMD11 proteasome 26S subunit, non-ATPase 11 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD11 mRNA CTD PMID:30303030 NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319 		JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD13 mRNA CTD PMID:30303030 NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984 		JBrowse link
G PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD2 mRNA CTD PMID:30303030 NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050 		JBrowse link
G PSMD5 proteasome 26S subunit, non-ATPase 5 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of PSMD5 mRNA CTD PMID:30303030 NCBI chr 9:120,816,053...120,842,922
Ensembl chr 9:120,815,496...120,842,951 		JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 increases expression ISO Isoproterenol results in increased expression of PSMD9 mRNA CTD PMID:30303030 NCBI chr12:121,888,790...121,918,297
Ensembl chr12:121,888,732...121,918,297 		JBrowse link
G PTEN phosphatase and tensin homolog increases expression ISO Isoproterenol results in increased expression of PTEN mRNA
Isoproterenol results in increased expression of PTEN mRNA; Isoproterenol results in increased expression of PTEN protein		 CTD PMID:16188065 PMID:20003209 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGDS prostaglandin D2 synthase increases expression ISO Isoproterenol results in increased expression of PTGDS mRNA CTD PMID:20003209 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 increases expression ISO Isoproterenol results in increased expression of PTGS1 mRNA CTD PMID:20003209 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression		 ISO
EXP		 Apigenin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein]; BAY 58-2667 inhibits the reaction [Isoproterenol results in increased expression of PTGS2 mRNA]; Doxorubicin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein]; mangostin inhibits the reaction [Isoproterenol results in increased expression of PTGS2 protein]
Isoproterenol results in decreased expression of PTGS2 mRNA
Isoproterenol results in increased expression of PTGS2 mRNA; Isoproterenol results in increased expression of PTGS2 protein		 CTD PMID:18424012 PMID:19466570 PMID:19667237 PMID:22908232 PMID:30152906 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH1R parathyroid hormone 1 receptor increases expression ISO Isoproterenol results in increased expression of PTH1R mRNA CTD PMID:20003209 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G PTP4A1 protein tyrosine phosphatase 4A1 increases expression ISO Isoproterenol results in increased expression of PTP4A1 mRNA CTD PMID:20003209 NCBI chr 6:63,516,440...63,583,588
Ensembl chr 6:63,521,746...63,583,588 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 increases expression ISO Isoproterenol results in increased expression of PTPN11 mRNA CTD PMID:20003209 NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918 		JBrowse link
G PTPN12 protein tyrosine phosphatase non-receptor type 12 increases expression ISO Isoproterenol results in increased expression of PTPN12 mRNA CTD PMID:20003209 NCBI chr 7:77,537,295...77,640,069
Ensembl chr 7:77,537,295...77,640,069 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Anisomycin inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Atenolol inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein] CTD PMID:17623046 NCBI chr11:18,727,928...18,792,721
Ensembl chr11:18,727,928...18,792,721 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D decreases expression ISO Isoproterenol results in decreased expression of PTPRD mRNA CTD PMID:21335049 NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F increases expression ISO Isoproterenol results in increased expression of PTPRF mRNA CTD PMID:20003209 NCBI chr 1:43,522,051...43,623,666
Ensembl chr 1:43,525,187...43,623,666 		JBrowse link
G PTX3 pentraxin 3 increases expression ISO Isoproterenol results in increased expression of PTX3 mRNA CTD PMID:20003209 PMID:21823215 NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633 		JBrowse link
G PVR PVR cell adhesion molecule increases expression ISO Isoproterenol results in increased expression of PVR mRNA CTD PMID:20211217 NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162 		JBrowse link
G PYGL glycogen phosphorylase L increases activity ISO Isoproterenol results in increased activity of PYGL protein CTD PMID:6430282 NCBI chr14:50,905,217...50,944,483
Ensembl chr14:50,857,891...50,944,483 		JBrowse link
G QDPR quinoid dihydropteridine reductase decreases expression ISO Isoproterenol results in decreased expression of QDPR mRNA CTD PMID:21335049 NCBI chr 4:17,486,395...17,512,090
Ensembl chr 4:17,460,261...17,512,206 		JBrowse link
G R3HDM1 R3H domain containing 1 increases expression ISO Isoproterenol results in increased expression of R3HDM1 mRNA CTD PMID:20003209 NCBI chr 2:135,531,484...135,725,269
Ensembl chr 2:135,531,455...135,725,270 		JBrowse link
G RAB1A RAB1A, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB1A mRNA CTD PMID:21335049 NCBI chr 2:65,086,854...65,130,106
Ensembl chr 2:65,070,696...65,130,331 		JBrowse link
G RAB27A RAB27A, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB27A mRNA CTD PMID:20003209 NCBI chr15:55,202,966...55,289,813
Ensembl chr15:55,202,966...55,319,113 		JBrowse link
G RAB33B RAB33B, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB33B mRNA CTD PMID:21335049 NCBI chr 4:139,438,376...139,476,609
Ensembl chr 4:139,453,232...139,476,609 		JBrowse link
G RAB4A RAB4A, member RAS oncogene family increases expression ISO Isoproterenol results in increased expression of RAB4A mRNA CTD PMID:20003209 NCBI chr 1:229,271,111...229,305,894
Ensembl chr 1:229,271,062...229,305,894 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein increases expression ISO Isoproterenol results in increased expression of RAD52 mRNA CTD PMID:20003209 NCBI chr12:911,736...991,122
Ensembl chr12:911,736...990,053 		JBrowse link
G RAMP1 receptor activity modifying protein 1 decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of RAMP1 mRNA
Isoproterenol results in increased expression of RAMP1 mRNA; Isoproterenol results in increased expression of RAMP1 protein		 CTD PMID:16987513 PMID:17250927 PMID:17306419 PMID:20003209 NCBI chr 2:237,858,880...237,912,106
Ensembl chr 2:237,858,893...237,912,106 		JBrowse link
G RAMP2 receptor activity modifying protein 2 multiple interactions
increases expression		 ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of RAMP2 mRNA
Isoproterenol results in increased expression of RAMP2 mRNA; Isoproterenol results in increased expression of RAMP2 protein		 CTD PMID:12732346 PMID:16987513 PMID:17250927 PMID:17306419 NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041 		JBrowse link
G RAMP3 receptor activity modifying protein 3 increases expression ISO Isoproterenol results in increased expression of RAMP3 mRNA; Isoproterenol results in increased expression of RAMP3 protein CTD PMID:16987513 PMID:17306419 NCBI chr 7:45,157,791...45,184,250
Ensembl chr 7:45,157,791...45,186,302 		JBrowse link
G RANBP9 RAN binding protein 9 increases expression ISO Isoproterenol results in increased expression of RANBP9 mRNA CTD PMID:20003209 NCBI chr 6:13,621,498...13,711,835
Ensembl chr 6:13,621,498...13,711,835 		JBrowse link
G RANGAP1 Ran GTPase activating protein 1 increases expression ISO Isoproterenol results in increased expression of RANGAP1 mRNA CTD PMID:21335049 NCBI chr22:41,244,779...41,302,369
Ensembl chr22:41,244,779...41,286,187 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 increases expression
increases response to substance
multiple interactions		 ISO Isoproterenol results in increased expression of RAPGEF3 mRNA
RAPGEF3 results in increased susceptibility to Isoproterenol
RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]		 CTD PMID:17557924 PMID:21745194 NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040 		JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 increases expression ISO Isoproterenol results in increased expression of RAPGEF4 mRNA CTD PMID:17557924 NCBI chr 2:172,735,318...173,052,893
Ensembl chr 2:172,735,274...173,052,893 		JBrowse link
G RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 increases expression ISO Isoproterenol results in increased expression of RAPH1 mRNA CTD PMID:20003209 NCBI chr 2:203,433,682...203,535,301
Ensembl chr 2:203,394,345...203,535,335 		JBrowse link
G RASA1 RAS p21 protein activator 1 affects localization
multiple interactions		 ISO Isoproterenol affects the localization of RASA1 protein
Isoproterenol results in increased expression of and results in increased phosphorylation of RASA1 protein		 CTD PMID:1382416 NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931 		JBrowse link
G RASD1 ras related dexamethasone induced 1 increases expression ISO Isoproterenol results in increased expression of RASD1 mRNA CTD PMID:20003209 NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395 		JBrowse link
G RASGEF1B RasGEF domain family member 1B increases expression ISO Isoproterenol results in increased expression of RASGEF1B mRNA CTD PMID:20003209 NCBI chr 4:81,426,393...81,471,907
Ensembl chr 4:81,426,393...82,044,244 		JBrowse link
G RASL10A RAS like family 10 member A increases expression ISO Isoproterenol results in increased expression of RASL10A mRNA CTD PMID:20003209 NCBI chr22:29,312,933...29,319,859
Ensembl chr22:29,312,933...29,319,679 		JBrowse link
G RASSF1 Ras association domain family member 1 decreases expression ISO Isoproterenol results in decreased expression of RASSF1 mRNA; Isoproterenol results in decreased expression of RASSF1 protein CTD PMID:24945829 NCBI chr 3:50,329,788...50,340,836
Ensembl chr 3:50,329,782...50,340,980 		JBrowse link
G RASSF4 Ras association domain family member 4 increases expression ISO Isoproterenol results in increased expression of RASSF4 mRNA CTD PMID:20003209 NCBI chr10:44,959,802...44,995,891
Ensembl chr10:44,959,407...44,995,891 		JBrowse link
G RBBP4 RB binding protein 4, chromatin remodeling factor decreases expression ISO Isoproterenol results in decreased expression of RBBP4 mRNA CTD PMID:20003209 NCBI chr 1:32,651,208...32,686,211
Ensembl chr 1:32,651,142...32,686,211 		JBrowse link
G RBL2 RB transcriptional corepressor like 2 increases expression ISO Isoproterenol results in increased expression of RBL2 mRNA CTD PMID:20003209 NCBI chr16:53,434,471...53,491,648
Ensembl chr16:53,433,977...53,491,648 		JBrowse link
G RBM33 RNA binding motif protein 33 increases expression ISO Isoproterenol results in increased expression of RBM33 mRNA CTD PMID:20003209 NCBI chr 7:155,644,661...155,781,480
Ensembl chr 7:155,644,451...155,781,485 		JBrowse link
G RBMX RNA binding motif protein X-linked decreases expression ISO Isoproterenol results in decreased expression of RBMX mRNA CTD PMID:20003209 NCBI chr  X:136,869,192...136,880,725
Ensembl chr  X:136,848,004...136,880,764 		JBrowse link
G RBP7 retinol binding protein 7 increases expression ISO Isoproterenol results in increased expression of RBP7 mRNA CTD PMID:20003209 NCBI chr 1:9,997,228...10,016,021
Ensembl chr 1:9,997,206...10,016,021 		JBrowse link
G REEP1 receptor accessory protein 1 decreases expression ISO Isoproterenol results in decreased expression of REEP1 mRNA CTD PMID:20003209 NCBI chr 2:86,213,993...86,338,083
Ensembl chr 2:86,213,993...86,338,083 		JBrowse link
G REG3A regenerating family member 3 alpha decreases expression
increases expression		 ISO Isoproterenol results in decreased expression of REG3B mRNA
Isoproterenol results in increased expression of REG3B mRNA		 CTD PMID:20211217 PMID:24286936 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753 		JBrowse link
G REG3G regenerating family member 3 gamma decreases expression EXP Isoproterenol results in decreased expression of REG3G mRNA CTD PMID:24286936 NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
affects localization
increases localization
increases activity		 ISO Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]; osthol inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]
Isoproterenol results in increased expression of RELA mRNA; Isoproterenol results in increased expression of RELA protein
Isoproterenol affects the localization of RELA protein
Isoproterenol results in increased localization of RELA protein
Isoproterenol results in increased activity of RELA protein
anethole inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; Isoproterenol affects the reaction [Lipopolysaccharides affects the localization of RELA protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of RELA protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; Sirolimus inhibits the reaction [Isoproterenol affects the localization of RELA protein]		 CTD PMID:15178407 PMID:15710352 PMID:18487443 PMID:21854795 PMID:25045214 More... NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G REN renin increases activity
multiple interactions
increases expression
increases secretion		 EXP
ISO		 Isoproterenol results in increased activity of REN protein
[Sodium, Dietary deficiency results in increased susceptibility to Isoproterenol] which results in increased secretion of REN protein; Isoproterenol promotes the reaction [CD38 gene mutant form results in increased activity of REN protein]
[aliskiren co-treated with Carvedilol] inhibits the reaction [Isoproterenol results in increased activity of REN protein]; aliskiren inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Losartan promotes the reaction [Isoproterenol results in increased expression of REN protein]; Quinapril promotes the reaction [Isoproterenol results in increased expression of REN protein]; Ramipril inhibits the reaction [Isoproterenol results in increased expression of REN protein]
Isoproterenol results in increased secretion of REN protein
Propranolol inhibits the reaction [Isoproterenol results in increased expression of REN protein]
Isoproterenol results in increased expression of REN mRNA		 CTD PMID:1653766 PMID:3515047 PMID:3910304 PMID:6314140 PMID:9539862 More... NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RFC5 replication factor C subunit 5 decreases expression ISO Isoproterenol results in decreased expression of RFC5 mRNA CTD PMID:21335049 NCBI chr12:118,016,703...118,041,448
Ensembl chr12:118,013,588...118,033,130 		JBrowse link
G RHOJ ras homolog family member J increases expression ISO Isoproterenol results in increased expression of RHOJ mRNA CTD PMID:20003209 NCBI chr14:63,204,443...63,293,508
Ensembl chr14:63,204,114...63,293,508 		JBrowse link
G RHOU ras homolog family member U increases expression ISO Isoproterenol results in increased expression of RHOU mRNA CTD PMID:20003209 NCBI chr 1:228,644,647...228,746,669
Ensembl chr 1:228,735,479...228,746,664 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of RIPK1 protein
thymoquinone inhibits the reaction [Isoproterenol results in increased expression of RIPK1 protein]		 CTD PMID:35940283 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of RIPK3 protein
thymoquinone inhibits the reaction [Isoproterenol results in increased expression of RIPK3 protein]		 CTD PMID:35940283 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RLN3 relaxin 3 increases expression ISO Isoproterenol results in increased expression of RLN3 mRNA; Isoproterenol results in increased expression of RLN3 protein CTD PMID:16112403 NCBI chr19:14,028,148...14,031,551
Ensembl chr19:14,028,148...14,031,551 		JBrowse link
G RNASE4 ribonuclease A family member 4 increases expression ISO Isoproterenol results in increased expression of RNASE4 mRNA CTD PMID:20003209 NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216 		JBrowse link
G RND1 Rho family GTPase 1 increases expression ISO Isoproterenol results in increased expression of RND1 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870 		JBrowse link
G RNF103 ring finger protein 103 increases expression ISO Isoproterenol results in increased expression of RNF103 mRNA CTD PMID:20003209 NCBI chr 2:86,603,393...86,623,877
Ensembl chr 2:86,603,398...86,623,866 		JBrowse link
G RNF128 ring finger protein 128 increases expression ISO Isoproterenol results in increased expression of RNF128 mRNA CTD PMID:20003209 NCBI chr  X:106,693,838...106,797,016
Ensembl chr  X:106,693,794...106,797,016 		JBrowse link
G RNF144B ring finger protein 144B increases expression ISO Isoproterenol results in increased expression of RNF144B mRNA CTD PMID:20003209 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870 		JBrowse link
G RNF207 ring finger protein 207 decreases expression ISO Isoproterenol results in decreased expression of RNF207 mRNA CTD PMID:20003209 NCBI chr 1:6,206,119...6,221,299
Ensembl chr 1:6,205,475...6,221,299 		JBrowse link
G RO60 Ro60, Y RNA binding protein increases expression ISO Isoproterenol results in increased expression of RO60 mRNA CTD PMID:20003209 NCBI chr 1:193,059,612...193,091,777
Ensembl chr 1:193,059,454...193,091,777 		JBrowse link
G RPL27A ribosomal protein L27a decreases expression ISO Isoproterenol results in decreased expression of RPL27A mRNA CTD PMID:20003209 NCBI chr11:8,682,792...8,689,872
Ensembl chr11:8,682,788...8,714,759 		JBrowse link
G RPL37A ribosomal protein L37a decreases expression ISO Isoproterenol results in decreased expression of RPL37A mRNA CTD PMID:21335049 NCBI chr 2:216,498,844...216,504,086
Ensembl chr 2:216,498,825...216,579,180 		JBrowse link
G RPN1 ribophorin I increases expression ISO Isoproterenol results in increased expression of RPN1 mRNA CTD PMID:21823215 NCBI chr 3:128,619,969...128,650,818
Ensembl chr 3:128,619,969...128,681,075 		JBrowse link
G RPS26 ribosomal protein S26 decreases expression ISO Isoproterenol results in decreased expression of RPS26 mRNA CTD PMID:21335049 NCBI chr12:56,041,918...56,044,697
Ensembl chr12:56,041,351...56,044,697 		JBrowse link
G RPS27A ribosomal protein S27a decreases expression ISO Isoproterenol results in decreased expression of RPS27A mRNA CTD PMID:21335049 NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853 		JBrowse link
G RPS3A ribosomal protein S3A decreases expression ISO Isoproterenol results in decreased expression of RPS3A mRNA CTD PMID:21335049 NCBI chr 4:151,099,628...151,104,642
Ensembl chr 4:151,099,624...151,104,642 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 increases phosphorylation
affects expression		 ISO Isoproterenol results in increased phosphorylation of RPS6KB1 protein
Isoproterenol affects the expression of RPS6KB1 mRNA		 CTD PMID:18812163 PMID:28099878 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator decreases expression ISO Isoproterenol results in decreased expression of RRAD mRNA CTD PMID:20003209 NCBI chr16:66,921,685...66,925,535
Ensembl chr16:66,921,685...66,925,535 		JBrowse link
G RSC1A1 regulator of solute carriers 1 increases expression ISO Isoproterenol results in increased expression of RSC1A1 mRNA CTD PMID:20003209 NCBI chr 1:15,659,713...15,662,033
Ensembl chr 1:15,659,713...15,662,033 		JBrowse link
G RSF1 remodeling and spacing factor 1 increases expression ISO Isoproterenol results in increased expression of RSF1 mRNA CTD PMID:20003209 NCBI chr11:77,660,009...77,872,232
Ensembl chr11:77,660,009...77,820,869 		JBrowse link
G RYR2 ryanodine receptor 2 multiple interactions
increases phosphorylation		 ISO
EXP		 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of RYR2 protein]
carvedilol inhibits the reaction [Isoproterenol results in increased phosphorylation of RYR2 protein]		 CTD PMID:16723803 PMID:21743453 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G S100A11 S100 calcium binding protein A11 increases expression ISO Isoproterenol results in increased expression of S100A11 protein CTD PMID:10886724 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G S100A4 S100 calcium binding protein A4 increases expression ISO Isoproterenol results in increased expression of S100A4 protein CTD PMID:10886724 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136 		JBrowse link
G S100A8 S100 calcium binding protein A8 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S100A8 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 1:153,390,032...153,422,583
Ensembl chr 1:153,390,032...153,391,073 		JBrowse link
G S100A9 S100 calcium binding protein A9 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S100A9 mRNA]
Isoproterenol results in increased expression of S100A9 protein
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of S100A9 protein]; pifithrin inhibits the reaction [Isoproterenol results in increased expression of S100A9 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C3 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of C5 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of CASP3 protein]		 CTD PMID:18089841 PMID:20003209 PMID:32924446 NCBI chr 1:153,357,854...153,361,023
Ensembl chr 1:153,357,854...153,361,023 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S1PR1 mRNA]; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of S1PR1 protein]
Isoproterenol results in increased expression of S1PR1 mRNA; Isoproterenol results in increased expression of S1PR1 protein		 CTD PMID:18089841 PMID:20003209 NCBI chr 1:101,236,899...101,242,313
Ensembl chr 1:101,236,865...101,243,713 		JBrowse link
G SAA1 serum amyloid A1 increases expression ISO Isoproterenol results in increased expression of SAA1 mRNA CTD PMID:21335049 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977 		JBrowse link
G SAA3P serum amyloid A3, pseudogene increases expression ISO Isoproterenol results in increased expression of SAA3 mRNA CTD PMID:20003209 NCBI chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132
Ensembl chr11:18,112,472...18,116,132 		JBrowse link
G SAA4 serum amyloid A4, constitutive increases expression ISO Isoproterenol results in increased expression of SAA4 mRNA CTD PMID:21335049 NCBI chr11:18,231,355...18,236,802
Ensembl chr11:18,231,355...18,236,802 		JBrowse link
G SBNO2 strawberry notch homolog 2 increases expression ISO Isoproterenol results in increased expression of SBNO2 mRNA CTD PMID:20003209 NCBI chr19:1,107,638...1,174,268
Ensembl chr19:1,107,637...1,174,268 		JBrowse link
G SCARA5 scavenger receptor class A member 5 increases expression ISO Isoproterenol results in increased expression of SCARA5 mRNA CTD PMID:20003209 NCBI chr 8:27,869,883...27,992,673
Ensembl chr 8:27,869,883...27,992,673 		JBrowse link
G SCARB2 scavenger receptor class B member 2 increases expression ISO Isoproterenol results in increased expression of SCARB2 mRNA CTD PMID:20003209 NCBI chr 4:76,158,737...76,234,532
Ensembl chr 4:76,158,737...76,234,536 		JBrowse link
G SCGB3A1 secretoglobin family 3A member 1 increases expression ISO Isoproterenol results in increased expression of SCGB3A1 mRNA CTD PMID:20003209 NCBI chr 5:180,590,105...180,591,499
Ensembl chr 5:180,590,105...180,591,499 		JBrowse link
G SCN3A sodium voltage-gated channel alpha subunit 3 increases expression ISO Isoproterenol results in increased expression of SCN3A mRNA CTD PMID:20003209 NCBI chr 2:165,087,526...165,204,050
Ensembl chr 2:165,087,526...165,204,050 		JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 decreases expression ISO Isoproterenol results in decreased expression of SCN4B mRNA CTD PMID:20003209 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 increases expression ISO Isoproterenol results in increased expression of SCN5A mRNA CTD PMID:17526999 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687 		JBrowse link
G SCN7A sodium voltage-gated channel alpha subunit 7 increases expression ISO Isoproterenol results in increased expression of SCN7A mRNA CTD PMID:20003209 NCBI chr 2:166,403,573...166,494,249
Ensembl chr 2:166,403,573...166,611,482 		JBrowse link
G SCPEP1 serine carboxypeptidase 1 increases expression ISO Isoproterenol results in increased expression of SCPEP1 mRNA CTD PMID:20003209 NCBI chr17:56,978,131...57,006,768
Ensembl chr17:56,978,129...57,006,768 		JBrowse link
G SCUBE2 signal peptide, CUB domain and EGF like domain containing 2 decreases expression ISO Isoproterenol results in decreased expression of SCUBE2 mRNA CTD PMID:20003209 NCBI chr11:9,019,476...9,091,599
Ensembl chr11:9,019,476...9,138,114 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 increases expression ISO Isoproterenol results in increased expression of SDF2L1 mRNA CTD PMID:21823215 NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299 		JBrowse link
G SELE selectin E multiple interactions EXP Isoproterenol inhibits the reaction [TNF protein results in increased secretion of SELE mRNA] CTD PMID:8780174 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SELENOP selenoprotein P increases expression ISO Isoproterenol results in increased expression of SELENOP mRNA CTD PMID:21335049 NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392 		JBrowse link
G SELL selectin L multiple interactions EXP Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased secretion of SELL protein]] CTD PMID:9762784 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702 		JBrowse link
G SEMA3G semaphorin 3G increases expression ISO Isoproterenol results in increased expression of SEMA3G mRNA CTD PMID:20003209 NCBI chr 3:52,433,035...52,445,103
Ensembl chr 3:52,433,035...52,445,103 		JBrowse link
G SEMA5A semaphorin 5A increases expression ISO Isoproterenol results in increased expression of SEMA5A mRNA CTD PMID:20003209 NCBI chr 5:9,035,033...9,546,075
Ensembl chr 5:9,035,033...9,546,075 		JBrowse link
G SERINC3 serine incorporator 3 increases expression ISO Isoproterenol results in increased expression of SERINC3 mRNA CTD PMID:20003209 NCBI chr20:44,496,221...44,522,070
Ensembl chr20:44,496,221...44,522,085 		JBrowse link
G SERPINA7 serpin family A member 7 increases expression ISO Isoproterenol results in increased expression of SERPINA7 mRNA CTD PMID:21335049 NCBI chr  X:106,032,435...106,038,727
Ensembl chr  X:106,032,435...106,038,727 		JBrowse link
G SERPINE1 serpin family E member 1 increases expression
decreases expression		 ISO Isoproterenol results in increased expression of SERPINE1 mRNA
Isoproterenol results in decreased expression of SERPINE1 protein		 CTD PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPING1 serpin family G member 1 increases expression ISO Isoproterenol results in increased expression of SERPING1 mRNA CTD PMID:20003209 NCBI chr11:57,597,685...57,614,848
Ensembl chr11:57,597,387...57,619,171 		JBrowse link
G SESN1 sestrin 1 increases expression ISO Isoproterenol results in increased expression of SESN1 mRNA CTD PMID:20003209 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,984,309...109,094,846 		JBrowse link
G SET SET nuclear proto-oncogene decreases expression ISO Isoproterenol results in decreased expression of SET mRNA CTD PMID:20003209 NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400 		JBrowse link
G SETDB2 SET domain bifurcated histone lysine methyltransferase 2 increases expression ISO Isoproterenol results in increased expression of SETDB2 mRNA CTD PMID:20003209 NCBI chr13:49,444,274...49,495,003
Ensembl chr13:49,444,274...49,495,003 		JBrowse link
G SFN stratifin decreases expression EXP Isoproterenol results in decreased expression of SFN mRNA CTD PMID:24286936 NCBI chr 1:26,863,149...26,864,456
Ensembl chr 1:26,863,149...26,864,456 		JBrowse link
G SGCG sarcoglycan gamma decreases expression ISO Isoproterenol results in decreased expression of SGCG CTD PMID:18808529 NCBI chr13:23,160,508...23,325,162
Ensembl chr13:23,180,979...23,325,162 		JBrowse link
G SGMS1 sphingomyelin synthase 1 increases expression ISO Isoproterenol results in increased expression of SGMS1 mRNA CTD PMID:20003209 NCBI chr10:50,305,600...50,625,184
Ensembl chr10:50,305,586...50,625,163 		JBrowse link
G SH3D19 SH3 domain containing 19 increases expression ISO Isoproterenol results in increased expression of SH3D19 mRNA CTD PMID:20003209 NCBI chr 4:151,120,281...151,325,605
Ensembl chr 4:151,102,751...151,325,605 		JBrowse link
G SH3KBP1 SH3 domain containing kinase binding protein 1 decreases expression ISO Isoproterenol results in decreased expression of SH3KBP1 mRNA CTD PMID:20003209 NCBI chr  X:19,533,977...19,887,600
Ensembl chr  X:19,533,977...19,887,600 		JBrowse link
G SHROOM2 shroom family member 2 increases expression ISO Isoproterenol results in increased expression of SHROOM2 mRNA CTD PMID:20003209 NCBI chr  X:9,786,429...9,949,443
Ensembl chr  X:9,786,429...9,949,443 		JBrowse link
G SIK1 salt inducible kinase 1 increases expression ISO Isoproterenol results in increased expression of SIK1 mRNA CTD PMID:34601065 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131 		JBrowse link
G SIRT6 sirtuin 6 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of SIRT6 mRNA
xanthone inhibits the reaction [Isoproterenol results in decreased expression of SIRT6 mRNA]		 CTD PMID:36414029 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566 		JBrowse link
G SIVA1 SIVA1 apoptosis inducing factor decreases expression ISO Isoproterenol results in decreased expression of SIVA1 mRNA CTD PMID:20003209 NCBI chr14:104,753,147...104,759,654
Ensembl chr14:104,753,147...104,768,494 		JBrowse link
G SIX4 SIX homeobox 4 increases expression ISO Isoproterenol results in increased expression of SIX4 mRNA CTD PMID:20003209 NCBI chr14:60,709,539...60,724,351
Ensembl chr14:60,709,539...60,724,351 		JBrowse link
G SLC10A6 solute carrier family 10 member 6 increases expression ISO Isoproterenol results in increased expression of SLC10A6 mRNA CTD PMID:20003209 NCBI chr 4:86,823,468...86,849,384
Ensembl chr 4:86,823,468...86,849,384 		JBrowse link
G SLC25A10 solute carrier family 25 member 10 decreases expression ISO Isoproterenol results in decreased expression of SLC25A10 mRNA CTD PMID:20003209 NCBI chr17:81,712,284...81,721,012
Ensembl chr17:81,712,236...81,721,016 		JBrowse link
G SLC25A20 solute carrier family 25 member 20 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of SLC25A20 mRNA CTD PMID:30303030 NCBI chr 3:48,856,926...48,898,882
Ensembl chr 3:48,856,926...48,898,904 		JBrowse link
G SLC25A30 solute carrier family 25 member 30 increases expression ISO Isoproterenol results in increased expression of SLC25A30 mRNA CTD PMID:20003209 NCBI chr13:45,393,316...45,434,016
Ensembl chr13:45,393,316...45,418,455 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression ISO Isoproterenol results in increased expression of SLC2A1 mRNA CTD PMID:20003209 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 decreases expression ISO Isoproterenol results in decreased expression of SLC2A4 protein CTD PMID:19826179 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC36A2 solute carrier family 36 member 2 decreases expression ISO Isoproterenol results in decreased expression of SLC36A2 mRNA CTD PMID:20003209 NCBI chr 5:151,314,972...151,347,559
Ensembl chr 5:151,314,972...151,347,590 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 increases expression ISO Isoproterenol results in increased expression of SLC40A1 mRNA CTD PMID:20003209 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758 		JBrowse link
G SLC43A3 solute carrier family 43 member 3 increases expression ISO Isoproterenol results in increased expression of SLC43A3 mRNA CTD PMID:20003209 NCBI chr11:57,406,954...57,427,580
Ensembl chr11:57,406,954...57,427,580 		JBrowse link
G SLC45A3 solute carrier family 45 member 3 increases expression ISO Isoproterenol results in increased expression of SLC45A3 mRNA CTD PMID:20003209 NCBI chr 1:205,657,851...205,680,509
Ensembl chr 1:205,657,851...205,680,509 		JBrowse link
G SLC6A1 solute carrier family 6 member 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of SLC6A1 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Isoproterenol results in increased expression of SLC6A1 protein]		 CTD PMID:30170018 NCBI chr 3:10,992,748...11,039,247
Ensembl chr 3:10,992,186...11,039,247 		JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP Isoproterenol results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 multiple interactions
increases expression		 ISO EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; Propranolol inhibits the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]
Isoproterenol results in increased expression of SLC8A1 mRNA		 CTD PMID:11179087 PMID:15621046 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053 		JBrowse link
G SLCO3A1 solute carrier organic anion transporter family member 3A1 increases expression ISO Isoproterenol results in increased expression of SLCO3A1 mRNA CTD PMID:20003209 NCBI chr15:91,853,708...92,172,435
Ensembl chr15:91,853,708...92,172,435 		JBrowse link
G SLPI secretory leukocyte peptidase inhibitor increases expression EXP Isoproterenol results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564 		JBrowse link
G SMAD1 SMAD family member 1 decreases expression ISO Isoproterenol results in decreased expression of SMAD1 mRNA CTD PMID:21335049 NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176 		JBrowse link
G SMAD2 SMAD family member 2 increases expression ISO Isoproterenol results in increased expression of SMAD2 mRNA CTD PMID:35014750 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD3 SMAD family member 3 increases expression ISO Isoproterenol results in increased expression of SMAD3 mRNA CTD PMID:35014750 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SMAP1 small ArfGAP 1 increases expression ISO Isoproterenol results in increased expression of SMAP1 mRNA CTD PMID:20003209 NCBI chr 6:70,667,883...70,862,015
Ensembl chr 6:70,667,776...70,862,011 		JBrowse link
G SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 increases expression ISO Isoproterenol results in increased expression of SMARCA1 mRNA CTD PMID:20003209 NCBI chr  X:129,446,506...129,523,490
Ensembl chr  X:129,446,501...129,523,500 		JBrowse link
G SMC5 structural maintenance of chromosomes 5 increases expression ISO Isoproterenol results in increased expression of SMC5 mRNA CTD PMID:20003209 NCBI chr 9:70,258,978...70,354,873
Ensembl chr 9:70,258,978...70,354,873 		JBrowse link
G SMOC2 SPARC related modular calcium binding 2 decreases expression ISO Isoproterenol results in decreased expression of SMOC2 mRNA CTD PMID:20003209 NCBI chr 6:168,441,184...168,667,992
Ensembl chr 6:168,441,151...168,673,445 		JBrowse link
G SMTN smoothelin decreases expression ISO Isoproterenol results in decreased expression of SMTN mRNA CTD PMID:20003209 NCBI chr22:31,064,118...31,104,624
Ensembl chr22:31,064,105...31,104,757 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 increases expression ISO Isoproterenol results in increased expression of SMURF2 mRNA CTD PMID:20003209 NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307 		JBrowse link
G SMYD1 SET and MYND domain containing 1 multiple interactions
decreases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of SMYD1 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 2:88,067,825...88,113,384
Ensembl chr 2:88,067,825...88,113,384 		JBrowse link
G SNAPIN SNAP associated protein decreases expression ISO Isoproterenol results in decreased expression of SNAPIN mRNA CTD PMID:20003209 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852 		JBrowse link
G SNRPB small nuclear ribonucleoprotein polypeptides B and B1 decreases expression ISO Isoproterenol results in decreased expression of SNRPB mRNA CTD PMID:21335049 NCBI chr20:2,461,642...2,470,789
Ensembl chr20:2,461,634...2,470,853 		JBrowse link
G SNRPF small nuclear ribonucleoprotein polypeptide F decreases expression ISO Isoproterenol results in decreased expression of SNRPF mRNA CTD PMID:20003209 NCBI chr12:95,858,952...95,866,140
Ensembl chr12:95,858,952...95,903,828 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of SOCS3 mRNA] CTD PMID:18089841 PMID:20003209 PMID:21335049 PMID:21823215 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression
decreases activity
multiple interactions
affects binding		 ISO
EXP		 Isoproterenol results in increased expression of SOD1 protein
Isoproterenol results in decreased activity of SOD1 protein
benidipine inhibits the reaction [Isoproterenol results in decreased activity of SOD1 protein]; Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein]; imetit inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein]; Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein
Isoproterenol binds to SOD1 protein; Isoproterenol binds to SOD1 protein mutant form		 CTD PMID:16702995 PMID:23612299 PMID:25269373 PMID:25496245 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO [ADCY5 protein results in increased susceptibility to Isoproterenol] which results in decreased expression of SOD2 protein; SOD2 protein inhibits the reaction [ADCY5 protein results in increased susceptibility to Isoproterenol]
[Isoproterenol co-treated with POSTN protein] results in decreased expression of SOD2 mRNA		 CTD PMID:23536361 PMID:30303030 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 increases expression ISO Isoproterenol results in increased expression of SORBS1 mRNA CTD PMID:20003209 NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414 		JBrowse link
G SORBS3 sorbin and SH3 domain containing 3 increases expression ISO Isoproterenol results in increased expression of SORBS3 mRNA CTD PMID:20003209 NCBI chr 8:22,544,973...22,575,788
Ensembl chr 8:22,544,986...22,575,788 		JBrowse link
G SORCS2 sortilin related VPS10 domain containing receptor 2 decreases expression ISO Isoproterenol results in decreased expression of SORCS2 mRNA CTD PMID:20003209 NCBI chr 4:7,192,538...7,742,827
Ensembl chr 4:7,192,538...7,742,827 		JBrowse link
G SORD sorbitol dehydrogenase decreases expression ISO Isoproterenol results in decreased expression of SORD mRNA CTD PMID:21335049 NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185 		JBrowse link
G SOX17 SRY-box transcription factor 17 increases expression ISO Isoproterenol results in increased expression of SOX17 mRNA CTD PMID:20003209 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SOX6 SRY-box transcription factor 6 decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of SOX6 mRNA; Isoproterenol results in decreased expression of SOX6 protein
JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 protein]		 CTD PMID:21177286 NCBI chr11:15,966,449...16,738,477
Ensembl chr11:15,966,449...16,739,591 		JBrowse link
G SOX9 SRY-box transcription factor 9 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of SOX9 protein
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of SOX9 protein]		 CTD PMID:35586685 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA] CTD PMID:10710348 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SPAG9 sperm associated antigen 9 increases expression ISO Isoproterenol results in increased expression of SPAG9 mRNA CTD PMID:20003209 NCBI chr17:50,962,174...51,120,868
Ensembl chr17:50,962,174...51,120,868 		JBrowse link
G SPHK1 sphingosine kinase 1 increases expression ISO Isoproterenol results in increased expression of SPHK1 mRNA CTD PMID:20003209 NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860 		JBrowse link
G SPHK2 sphingosine kinase 2 decreases expression ISO Isoproterenol results in decreased expression of SPHK2 mRNA CTD PMID:20003209 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717 		JBrowse link
G SPNS2 SPNS lysolipid transporter 2, sphingosine-1-phosphate increases expression ISO Isoproterenol results in increased expression of SPNS2 mRNA CTD PMID:20003209 NCBI chr17:4,498,881...4,539,035
Ensembl chr17:4,498,881...4,539,035 		JBrowse link
G SPOCK2 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 increases expression ISO Isoproterenol results in increased expression of SPOCK2 mRNA CTD PMID:20003209 NCBI chr10:72,059,034...72,089,032
Ensembl chr10:72,059,034...72,089,032 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression
decreases expression		 ISO Isoproterenol results in increased expression of SPP1 mRNA
Isoproterenol results in decreased expression of SPP1 mRNA		 CTD PMID:20003209 PMID:20211217 PMID:21335049 PMID:23558518 PMID:24286936 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Isoproterenol results in increased expression of SPSB1 mRNA CTD PMID:20003209 NCBI chr 1:9,292,894...9,369,532
Ensembl chr 1:9,292,894...9,369,532 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 decreases expression ISO Isoproterenol results in decreased expression of SPTA1 mRNA CTD PMID:20003209 NCBI chr 1:158,610,704...158,686,715
Ensembl chr 1:158,610,704...158,686,715 		JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 increases expression ISO Isoproterenol results in increased expression of SPTLC2 mRNA CTD PMID:20003209 NCBI chr14:77,505,997...77,616,637
Ensembl chr14:77,505,997...77,616,637 		JBrowse link
G SQLE squalene epoxidase increases expression ISO Isoproterenol results in increased expression of SQLE mRNA CTD PMID:21335049 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SQSTM1 sequestosome 1 increases expression ISO Isoproterenol results in increased expression of SQSTM1 mRNA CTD PMID:20003209 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G SRM spermidine synthase increases expression ISO Isoproterenol results in increased expression of SRM mRNA CTD PMID:21335049 NCBI chr 1:11,054,589...11,060,018
Ensembl chr 1:11,054,584...11,060,020 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 decreases expression ISO Isoproterenol results in decreased expression of SRSF2 mRNA CTD PMID:20003209 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333 		JBrowse link
G ST7L suppression of tumorigenicity 7 like increases expression ISO Isoproterenol results in increased expression of ST7L mRNA CTD PMID:20003209 NCBI chr 1:112,517,803...112,619,684
Ensembl chr 1:112,523,514...112,620,825 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 increases expression ISO Isoproterenol results in increased expression of ST8SIA6 mRNA CTD PMID:20003209 NCBI chr10:17,315,421...17,454,595
Ensembl chr10:17,315,421...17,454,595 		JBrowse link
G STARD5 StAR related lipid transfer domain containing 5 increases expression ISO Isoproterenol results in increased expression of STARD5 mRNA CTD PMID:20003209 NCBI chr15:81,309,053...81,324,141
Ensembl chr15:81,309,053...81,324,183 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT1 mRNA CTD PMID:30303030 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 affects localization
multiple interactions
increases phosphorylation
increases expression		 ISO
EXP		 Isoproterenol affects the localization of STAT3 protein
STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol]
STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]
Isoproterenol results in increased phosphorylation of STAT3 protein
Isoproterenol results in increased expression of STAT3 mRNA
Isoproterenol results in increased expression of STAT3; Isoproterenol results in increased expression of STAT3 protein
[Isoproterenol co-treated with POSTN protein] results in decreased expression of STAT3 mRNA; Betaine promotes the reaction [Isoproterenol results in increased phosphorylation of STAT3 protein]; Cyclosporine inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]; Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein; Verapamil inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased expression of STAT3 protein]		 CTD PMID:19299911 PMID:21335049 PMID:25080425 PMID:29355689 PMID:30303030 More... NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A decreases expression ISO Isoproterenol results in decreased expression of STAT5A mRNA CTD PMID:20003209 NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943 		JBrowse link
G STC1 stanniocalcin 1 increases expression ISO Isoproterenol results in increased expression of STC1 mRNA CTD PMID:20003209 NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806 		JBrowse link
G STON1 stonin 1 increases expression ISO Isoproterenol results in increased expression of STON1 mRNA CTD PMID:20003209 NCBI chr 2:48,530,154...48,598,513
Ensembl chr 2:48,529,383...48,598,513 		JBrowse link
G STT3A STT3 oligosaccharyltransferase complex catalytic subunit A increases expression ISO Isoproterenol results in increased expression of STT3A mRNA CTD PMID:21823215 NCBI chr11:125,591,769...125,623,091
Ensembl chr11:125,591,712...125,625,215 		JBrowse link
G STX3 syntaxin 3 increases expression ISO Isoproterenol results in increased expression of STX3 mRNA CTD PMID:20003209 NCBI chr11:59,754,188...59,805,878
Ensembl chr11:59,713,456...59,805,882 		JBrowse link
G SULT1A2 sulfotransferase family 1A member 2 increases expression ISO Isoproterenol results in increased expression of SULT1A1 mRNA CTD PMID:20003209 NCBI chr16:28,591,943...28,597,050
Ensembl chr16:28,591,943...28,597,050 		JBrowse link
G SULT1B1 sulfotransferase family 1B member 1 decreases expression ISO Isoproterenol results in decreased expression of SULT1B1 mRNA CTD PMID:21335049 NCBI chr 4:69,721,167...69,760,620
Ensembl chr 4:69,721,167...69,787,961 		JBrowse link
G SYK spleen associated tyrosine kinase increases expression ISO Isoproterenol results in increased expression of SYK mRNA CTD PMID:20003209 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549 		JBrowse link
G SYN2 synapsin II increases expression ISO Isoproterenol results in increased expression of SYN2 mRNA CTD PMID:20003209 NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032 		JBrowse link
G SYT12 synaptotagmin 12 increases expression ISO Isoproterenol results in increased expression of SYT12 mRNA CTD PMID:20003209 NCBI chr11:67,006,771...67,050,863
Ensembl chr11:67,006,778...67,050,863 		JBrowse link
G TAC1 tachykinin precursor 1 affects response to substance ISO TAC1 protein affects the susceptibility to Isoproterenol CTD PMID:11270094 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TACC2 transforming acidic coiled-coil containing protein 2 increases expression ISO Isoproterenol results in increased expression of TACC2 mRNA CTD PMID:20003209 NCBI chr10:121,989,163...122,254,542
Ensembl chr10:121,989,163...122,254,545 		JBrowse link
G TAX1BP1 Tax1 binding protein 1 increases expression ISO Isoproterenol results in increased expression of TAX1BP1 mRNA CTD PMID:20003209 NCBI chr 7:27,739,373...27,829,767
Ensembl chr 7:27,739,331...27,844,564 		JBrowse link
G TBC1D15 TBC1 domain family member 15 increases expression ISO Isoproterenol results in increased expression of TBC1D15 mRNA CTD PMID:20003209 NCBI chr12:71,839,759...71,924,313
Ensembl chr12:71,839,707...71,927,248 		JBrowse link
G TBK1 TANK binding kinase 1 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of TBK1 mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of TBK1 mRNA		 CTD PMID:20003209 PMID:30303030 NCBI chr12:64,452,120...64,502,114
Ensembl chr12:64,452,090...64,502,114 		JBrowse link
G TBL1XR1 TBL1X/Y related 1 increases expression ISO Isoproterenol results in increased expression of TBL1XR1 mRNA CTD PMID:20003209 NCBI chr 3:177,019,344...177,201,800
Ensembl chr 3:177,019,340...177,228,000 		JBrowse link
G TCF23 transcription factor 23 increases expression ISO Isoproterenol results in increased expression of TCF23 mRNA CTD PMID:20003209 NCBI chr 2:27,149,004...27,156,974
Ensembl chr 2:27,149,004...27,156,974 		JBrowse link
G TCF3 transcription factor 3 decreases expression ISO Isoproterenol results in decreased expression of TCF3 mRNA CTD PMID:20003209 NCBI chr19:1,609,292...1,652,615
Ensembl chr19:1,609,291...1,652,615 		JBrowse link
G TCN2 transcobalamin 2 increases expression ISO Isoproterenol results in increased expression of TCN2 mRNA CTD PMID:20003209 NCBI chr22:30,607,174...30,627,271
Ensembl chr22:30,607,003...30,627,271 		JBrowse link
G TDG thymine DNA glycosylase increases expression ISO Isoproterenol results in increased expression of TDG mRNA CTD PMID:21335049 NCBI chr12:103,965,872...103,988,874
Ensembl chr12:103,965,822...103,988,874 		JBrowse link
G TECRL trans-2,3-enoyl-CoA reductase like increases expression ISO Isoproterenol results in increased expression of TECRL mRNA CTD PMID:20003209 NCBI chr 4:64,276,298...64,409,460
Ensembl chr 4:64,275,257...64,409,468 		JBrowse link
G TFDP2 transcription factor Dp-2 increases expression ISO Isoproterenol results in increased expression of TFDP2 mRNA CTD PMID:20003209 NCBI chr 3:141,944,428...142,149,544
Ensembl chr 3:141,944,428...142,149,544 		JBrowse link
G TFRC transferrin receptor decreases expression EXP
ISO		 Isoproterenol results in decreased expression of TFRC protein
Isoproterenol results in decreased expression of TFRC mRNA		 CTD PMID:2989362 PMID:20003209 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TGFB1 transforming growth factor beta 1 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in decreased expression of TGFB1 mRNA
isoprenaline increases expression of Tgfb1 protein in blood serum
Isoproterenol results in increased expression of TGFB1 mRNA; Isoproterenol results in increased expression of TGFB1 protein
celastrol methyl ester inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; osthol inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; osthol inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]
BAY 58-2667 inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of TGFB1 protein]		 CTD
RGD		 PMID:11821714 PMID:19667237 PMID:21854795 PMID:24117263 PMID:35014750 More... RGD:156430318 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFB2 transforming growth factor beta 2 increases expression ISO Isoproterenol results in increased expression of TGFB2 mRNA CTD PMID:20211217 PMID:23558518 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of TGFBR2 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142 		JBrowse link
G TGM2 transglutaminase 2 increases expression ISO Isoproterenol results in increased expression of TGM2 mRNA CTD PMID:20003209 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G THBS2 thrombospondin 2 increases expression ISO Isoproterenol results in increased expression of THBS2 mRNA CTD PMID:20003209 NCBI chr 6:169,215,785...169,253,846
Ensembl chr 6:169,215,780...169,254,050 		JBrowse link
G THOC3 THO complex subunit 3 decreases expression ISO Isoproterenol results in decreased expression of THOC3 mRNA CTD PMID:20003209 NCBI chr 5:175,959,531...175,968,315
Ensembl chr 5:175,917,873...176,034,680 		JBrowse link
G THRA thyroid hormone receptor alpha multiple interactions
increases expression		 ISO [Isoproterenol co-treated with Amiodarone] results in increased expression of THRA mRNA alternative form
Isoproterenol results in increased expression of THRA mRNA alternative form		 CTD PMID:7598731 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867 		JBrowse link
G THRB thyroid hormone receptor beta multiple interactions
increases expression		 ISO [Isoproterenol co-treated with Amiodarone] results in increased expression of THRB mRNA alternative form; Amiodarone inhibits the reaction [Isoproterenol results in increased expression of THRB mRNA alternative form] CTD PMID:7598731 NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756 		JBrowse link
G THY1 Thy-1 cell surface antigen decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of THY1
Propranolol inhibits the reaction [Isoproterenol results in decreased expression of THY1]		 CTD PMID:7558147 NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 increases expression ISO Isoproterenol results in increased expression of TIAM1 mRNA CTD PMID:20211217 NCBI chr21:31,118,418...31,559,087
Ensembl chr21:31,118,416...31,559,977 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of TIMP1 mRNA
Isoproterenol results in increased expression of TIMP1 mRNA; Isoproterenol results in increased expression of TIMP1 protein
Isoproterenol results in decreased expression of TIMP1 mRNA		 CTD PMID:20003209 PMID:20211217 PMID:23558518 PMID:24286936 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Isoproterenol results in increased expression of TIMP3 protein
Isoproterenol results in decreased expression of TIMP3 protein
natakalim inhibits the reaction [Isoproterenol results in decreased expression of TIMP3 protein]		 CTD PMID:24286936 PMID:27890915 NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of TIMP4 mRNA
Isoproterenol results in decreased expression of TIMP4 protein		 CTD PMID:20003209 PMID:24286936 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912 		JBrowse link
G TINAGL1 tubulointerstitial nephritis antigen like 1 increases expression ISO Isoproterenol results in increased expression of TINAGL1 mRNA CTD PMID:20003209 NCBI chr 1:31,576,515...31,587,686
Ensembl chr 1:31,576,485...31,587,686 		JBrowse link
G TK1 thymidine kinase 1 decreases expression ISO Isoproterenol results in decreased expression of TK1 mRNA CTD PMID:21335049 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233 		JBrowse link
G TLE1 TLE family member 1, transcriptional corepressor increases expression ISO Isoproterenol results in increased expression of TLE1 mRNA CTD PMID:20003209 NCBI chr 9:81,583,683...81,689,547
Ensembl chr 9:81,583,683...81,689,547 		JBrowse link
G TLR4 toll like receptor 4 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of TLR4 mRNA
anethole inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA]; anethole inhibits the reaction [Isoproterenol results in increased expression of TLR4 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of TLR4 mRNA]
Isoproterenol results in increased expression of TLR4 mRNA; Isoproterenol results in increased expression of TLR4 protein		 CTD PMID:20003209 PMID:24842192 PMID:35430261 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TMBIM1 transmembrane BAX inhibitor motif containing 1 increases expression ISO Isoproterenol results in increased expression of TMBIM1 mRNA CTD PMID:20003209 NCBI chr 2:218,274,197...218,292,503
Ensembl chr 2:218,274,197...218,292,586 		JBrowse link
G TMCC3 transmembrane and coiled-coil domain family 3 increases expression ISO Isoproterenol results in increased expression of TMCC3 mRNA CTD PMID:20003209 NCBI chr12:94,567,122...94,650,557
Ensembl chr12:94,567,122...94,650,557 		JBrowse link
G TMEM140 transmembrane protein 140 increases expression ISO Isoproterenol results in increased expression of TMEM140 mRNA CTD PMID:20003209 NCBI chr 7:135,148,072...135,166,215
Ensembl chr 7:135,148,072...135,166,215 		JBrowse link
G TMEM141 transmembrane protein 141 decreases expression ISO Isoproterenol results in decreased expression of TMEM141 mRNA CTD PMID:20003209 NCBI chr 9:136,791,344...136,793,317
Ensembl chr 9:136,791,344...136,793,317 		JBrowse link
G TMEM144 transmembrane protein 144 increases expression ISO Isoproterenol results in increased expression of TMEM144 mRNA CTD PMID:20003209 NCBI chr 4:158,210,486...158,255,416
Ensembl chr 4:158,201,604...158,255,416 		JBrowse link
G TMEM164 transmembrane protein 164 increases expression ISO Isoproterenol results in increased expression of TMEM164 mRNA CTD PMID:20003209 NCBI chr  X:110,002,369...110,184,251
Ensembl chr  X:110,002,631...110,182,734 		JBrowse link
G TMEM176A transmembrane protein 176A increases expression ISO Isoproterenol results in increased expression of TMEM176A mRNA CTD PMID:20003209 NCBI chr 7:150,800,769...150,805,118
Ensembl chr 7:150,800,403...150,805,118 		JBrowse link
G TMEM38B transmembrane protein 38B increases expression ISO Isoproterenol results in increased expression of TMEM38B mRNA CTD PMID:20003209 NCBI chr 9:105,694,541...105,776,629
Ensembl chr 9:105,694,541...105,776,629 		JBrowse link
G TMOD4 tropomodulin 4 decreases expression ISO Isoproterenol results in decreased expression of TMOD4 mRNA CTD PMID:20003209 NCBI chr 1:151,169,987...151,175,981
Ensembl chr 1:151,169,986...151,176,284 		JBrowse link
G TMSB4X thymosin beta 4 X-linked decreases expression ISO Isoproterenol results in decreased expression of TMSB4X mRNA CTD PMID:21335049 NCBI chr  X:12,975,110...12,977,223
Ensembl chr  X:12,975,110...12,977,227 		JBrowse link
G TMTC1 transmembrane O-mannosyltransferase targeting cadherins 1 increases expression ISO Isoproterenol results in increased expression of TMTC1 mRNA CTD PMID:20003209 NCBI chr12:29,500,813...29,784,759
Ensembl chr12:29,500,840...29,784,759 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 decreases expression ISO Isoproterenol results in decreased expression of TMX1 mRNA CTD PMID:20003209 NCBI chr14:51,240,247...51,257,655
Ensembl chr14:51,240,162...51,257,655 		JBrowse link
G TNF tumor necrosis factor multiple interactions
increases secretion
increases expression
decreases expression		 EXP
ISO		 Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Isoproterenol inhibits the reaction [TNF protein results in increased secretion of SELE mRNA]
Isoproterenol results in increased secretion of TNF protein
Isoproterenol results in increased expression of TNF mRNA; Isoproterenol results in increased expression of TNF protein
Isoproterenol results in decreased expression of TNF mRNA
Isoproterenol results in increased expression of TNF; Isoproterenol results in increased expression of TNF mRNA
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; [Isoproterenol co-treated with POSTN protein] results in increased expression of TNF mRNA; anethole inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; bellidifolin inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; erdosteine inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; ferruginol inhibits the reaction [Isoproterenol results in increased secretion of TNF protein]; geraniol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Isoproterenol inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Isoproterenol inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Isoproterenol results in increased expression of and results in increased secretion of TNF protein; mangiferin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; mangostin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; punicalagin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARA protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of PPARGC1A protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of TNF protein]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
bellidifolin inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; SB 206553 inhibits the reaction [Isoproterenol results in increased expression of TNF]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of TNF protein]		 CTD PMID:8096834 PMID:8780174 PMID:9038718 PMID:9688336 PMID:10525314 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 decreases expression EXP Isoproterenol results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046 		JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A increases expression ISO Isoproterenol results in increased expression of TNFRSF12A mRNA CTD PMID:21335049 NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A decreases expression
increases expression		 EXP
ISO		 Isoproterenol results in decreased expression of TNFRSF1A mRNA
Isoproterenol results in increased expression of TNFRSF1A mRNA		 CTD PMID:24286936 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF10 TNF superfamily member 10 increases expression ISO Isoproterenol results in increased expression of TNFSF10 mRNA CTD PMID:24286936 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNIK TRAF2 and NCK interacting kinase increases expression ISO Isoproterenol results in increased expression of TNIK mRNA CTD PMID:20003209 NCBI chr 3:171,058,414...171,460,408
Ensembl chr 3:171,058,414...171,460,408 		JBrowse link
G TNKS tankyrase increases expression ISO Isoproterenol results in increased expression of TNKS mRNA CTD PMID:20003209 NCBI chr 8:9,555,912...9,782,346
Ensembl chr 8:9,555,912...9,782,346 		JBrowse link
G TNNI3 troponin I3, cardiac type increases expression
increases secretion
multiple interactions		 ISO Isoproterenol results in increased expression of TNNI3 protein
Isoproterenol results in increased secretion of TNNI3 protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; anethole inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]]; pyrvinium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of TNNI3 protein]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; thymoquinone inhibits the reaction [Isoproterenol results in increased secretion of TNNI3 protein]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]; xanthone inhibits the reaction [Isoproterenol results in increased expression of TNNI3 protein]		 CTD PMID:17654401 PMID:19549929 PMID:19854236 PMID:22878004 PMID:24286936 More... NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773 		JBrowse link
G TNNT1 troponin T1, slow skeletal type multiple interactions ISO Isoproterenol results in increased expression of and results in increased secretion of TNNT1 protein; oleuropein inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of TNNT1 protein] CTD PMID:26056852 NCBI chr19:55,132,698...55,149,206
Ensembl chr19:55,132,698...55,149,206 		JBrowse link
G TNNT2 troponin T2, cardiac type affects expression
decreases expression
multiple interactions
increases secretion
increases expression		 ISO Isoproterenol affects the expression of TNNT2 protein
Isoproterenol results in decreased expression of TNNT2 protein
5-Methoxypsoralen inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; ferruginol inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein]; Lutein inhibits the reaction [Isoproterenol results in decreased expression of TNNT2 protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein]; Vincristine inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein]		 CTD PMID:17188415 PMID:17654401 PMID:17848144 PMID:19146839 PMID:19812120 More... NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764 		JBrowse link
G TNPO1 transportin 1 increases expression ISO Isoproterenol results in increased expression of TNPO1 mRNA CTD PMID:20003209 NCBI chr 5:72,816,661...72,914,388
Ensembl chr 5:72,816,312...72,916,733 		JBrowse link
G TP53 tumor protein p53 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of TP53 protein
Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein; pifithrin inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; S100A9 protein affects the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]
Isoproterenol results in decreased expression of TP53 mRNA
Isoproterenol results in increased expression of TP53 mRNA		 CTD PMID:19466570 PMID:24286936 PMID:32924446 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TP53INP1 tumor protein p53 inducible nuclear protein 1 multiple interactions
increases expression		 ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of TRP53INP1 mRNA] CTD PMID:18089841 PMID:20003209 NCBI chr 8:94,925,972...94,949,378
Ensembl chr 8:94,925,972...94,949,378 		JBrowse link
G TPM1 tropomyosin 1 decreases expression ISO Isoproterenol results in decreased expression of TPM1 mRNA CTD PMID:20003209 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TPO thyroid peroxidase decreases activity ISO Isoproterenol results in decreased activity of TPO protein CTD PMID:26884060 NCBI chr 2:1,374,047...1,543,673
Ensembl chr 2:1,374,066...1,543,711 		JBrowse link
G TRAK1 trafficking kinesin protein 1 decreases expression ISO Isoproterenol results in decreased expression of TRAK1 mRNA CTD PMID:20003209 NCBI chr 3:42,013,093...42,225,890
Ensembl chr 3:42,013,802...42,225,890 		JBrowse link
G TRIM7 tripartite motif containing 7 decreases expression ISO Isoproterenol results in decreased expression of TRIM7 mRNA CTD PMID:20003209 NCBI chr 5:181,193,924...181,205,196
Ensembl chr 5:181,193,924...181,205,293 		JBrowse link
G TRMT5 tRNA methyltransferase 5 increases expression ISO Isoproterenol results in increased expression of TRMT5 mRNA CTD PMID:20003209 NCBI chr14:60,971,441...60,981,690
Ensembl chr14:60,971,441...60,981,170 		JBrowse link
G TSC22D3 TSC22 domain family member 3 increases expression ISO Isoproterenol results in increased expression of TSC22D3 mRNA CTD PMID:20003209 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342 		JBrowse link
G TSC22D4 TSC22 domain family member 4 decreases expression ISO Isoproterenol results in decreased expression of TSC22D4 mRNA CTD PMID:20003209 NCBI chr 7:100,466,519...100,479,214
Ensembl chr 7:100,463,359...100,479,232 		JBrowse link
G TSFM Ts translation elongation factor, mitochondrial decreases expression ISO Isoproterenol results in decreased expression of TSFM mRNA CTD PMID:20003209 NCBI chr12:57,782,787...57,802,856
Ensembl chr12:57,782,761...57,808,071 		JBrowse link
G TSPYL4 TSPY like 4 increases expression ISO Isoproterenol results in increased expression of TSPYL4 mRNA CTD PMID:20003209 NCBI chr 6:116,249,964...116,254,075
Ensembl chr 6:116,249,964...116,254,075 		JBrowse link
G TTLL7 tubulin tyrosine ligase like 7 increases expression ISO Isoproterenol results in increased expression of TTLL7 mRNA CTD PMID:20003209 NCBI chr 1:83,865,024...83,999,132
Ensembl chr 1:83,865,024...83,999,150 		JBrowse link
G TTR transthyretin increases expression ISO Isoproterenol results in increased expression of TTR mRNA CTD PMID:20003209 NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833 		JBrowse link
G TUBA1B tubulin alpha 1b decreases expression ISO Isoproterenol results in decreased expression of TUBA1B mRNA CTD PMID:20003209 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBA4A tubulin alpha 4a decreases expression ISO Isoproterenol results in decreased expression of TUBA4A mRNA CTD PMID:20003209 NCBI chr 2:219,249,710...219,254,740
Ensembl chr 2:219,249,710...219,277,902 		JBrowse link
G TUBA8 tubulin alpha 8 decreases expression ISO Isoproterenol results in decreased expression of TUBA8 mRNA CTD PMID:20003209 NCBI chr22:18,110,809...18,131,732
Ensembl chr22:18,110,100...18,146,683 		JBrowse link
G TUBB tubulin beta class I decreases expression ISO Isoproterenol results in decreased expression of TUBB5 mRNA CTD PMID:20003209 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538 		JBrowse link
G TUBB2A tubulin beta 2A class IIa decreases expression ISO Isoproterenol results in decreased expression of TUBB2A mRNA CTD PMID:20003209 NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544 		JBrowse link
G TUBB6 tubulin beta 6 class V increases expression ISO Isoproterenol results in increased expression of TUBB6 mRNA CTD PMID:20211217 NCBI chr18:12,307,669...12,329,826
Ensembl chr18:12,307,669...12,344,320 		JBrowse link
G TXN thioredoxin decreases expression
multiple interactions		 ISO Isoproterenol results in decreased expression of TXN1 mRNA
Lutein inhibits the reaction [Isoproterenol results in decreased expression of TXN protein]		 CTD PMID:21335049 PMID:34435724 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507 		JBrowse link
G TXNDC5 thioredoxin domain containing 5 decreases expression ISO Isoproterenol results in decreased expression of TXNDC5 mRNA CTD PMID:20003209 NCBI chr 6:7,881,517...7,910,788
Ensembl chr 6:7,881,517...7,910,788 		JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions
increases expression		 ISO Lutein inhibits the reaction [Isoproterenol results in increased expression of TXNIP protein] CTD PMID:34435724 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G TXNRD2 thioredoxin reductase 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of TXNRD2 mRNA CTD PMID:30303030 NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820 		JBrowse link
G TYW1 tRNA-yW synthesizing protein 1 homolog increases expression ISO Isoproterenol results in increased expression of TYW1 mRNA CTD PMID:20003209 NCBI chr 7:66,996,833...67,239,514
Ensembl chr 7:66,995,173...67,239,514 		JBrowse link
G U2AF1 U2 small nuclear RNA auxiliary factor 1 decreases expression ISO Isoproterenol results in decreased expression of U2AF1 mRNA CTD PMID:20003209 NCBI chr21:43,092,956...43,107,578
Ensembl chr21:43,092,956...43,107,570 		JBrowse link
G UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 increases expression ISO Isoproterenol results in increased expression of UAP1 mRNA CTD PMID:20003209 NCBI chr 1:162,561,531...162,601,240
Ensembl chr 1:162,561,722...162,601,240 		JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of UBA1 mRNA CTD PMID:30303030 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128 		JBrowse link
G UBB ubiquitin B increases expression ISO Isoproterenol results in increased expression of UBB mRNA CTD PMID:21335049 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745 		JBrowse link
G UBC ubiquitin C decreases expression ISO Isoproterenol results in decreased expression of UBC mRNA CTD PMID:20003209 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368 		JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 increases expression ISO Isoproterenol results in increased expression of UBE2D1 mRNA CTD PMID:30303030 NCBI chr10:58,335,006...58,370,748
Ensembl chr10:58,334,979...58,370,751 		JBrowse link
G UBR2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Isoproterenol results in increased expression of UBR2 mRNA CTD PMID:20003209 NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 increases expression ISO Isoproterenol results in increased expression of UCHL1 mRNA CTD PMID:20003209 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G UCK2 uridine-cytidine kinase 2 increases expression ISO Isoproterenol results in increased expression of UCK2 mRNA CTD PMID:20211217 NCBI chr 1:165,827,614...165,911,618
Ensembl chr 1:165,827,614...165,911,618 		JBrowse link
G UCP1 uncoupling protein 1 increases expression ISO Isoproterenol results in increased expression of UCP1 protein CTD PMID:17250927 NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961 		JBrowse link
G UCP2 uncoupling protein 2 increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of UCP2 mRNA
Edaravone inhibits the reaction [Isoproterenol results in increased expression of UCP2 mRNA]; Edaravone inhibits the reaction [Isoproterenol results in increased expression of UCP2 protein]
Isoproterenol results in increased expression of UCP2 mRNA; Isoproterenol results in increased expression of UCP2 protein		 CTD PMID:16580698 PMID:20003209 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,672...73,982,843 		JBrowse link
G UCP3 uncoupling protein 3 increases expression
decreases expression		 EXP
ISO		 Isoproterenol results in increased expression of UCP3 mRNA
Isoproterenol results in decreased expression of UCP3 mRNA		 CTD PMID:24286936 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085 		JBrowse link
G UGDH UDP-glucose 6-dehydrogenase increases expression ISO Isoproterenol results in increased expression of UGDH mRNA CTD PMID:21335049 NCBI chr 4:39,498,755...39,527,439
Ensembl chr 4:39,498,755...39,528,311 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 increases expression ISO Isoproterenol results in increased expression of UGT1A2 mRNA CTD PMID:20003209 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UNG uracil DNA glycosylase increases expression ISO Isoproterenol results in increased expression of UNG mRNA CTD PMID:21335049 NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,597...109,126,725 		JBrowse link
G UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 decreases expression ISO Isoproterenol results in decreased expression of UQCC1 mRNA CTD PMID:20003209 NCBI chr20:35,302,578...35,411,973
Ensembl chr20:35,302,566...35,412,031 		JBrowse link
G USP2 ubiquitin specific peptidase 2 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of USP2 mRNA CTD PMID:30303030 NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711 		JBrowse link
G UVRAG UV radiation resistance associated increases expression ISO Isoproterenol results in increased expression of UVRAG mRNA CTD PMID:20003209 NCBI chr11:75,815,210...76,144,232
Ensembl chr11:75,815,210...76,144,232 		JBrowse link
G VASP vasodilator stimulated phosphoprotein multiple interactions
decreases expression		 ISO natakalim inhibits the reaction [Isoproterenol results in decreased expression of VASP protein] CTD PMID:27890915 NCBI chr19:45,507,479...45,526,983
Ensembl chr19:45,506,579...45,526,989 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 decreases expression ISO Isoproterenol results in decreased expression of VCAM1 mRNA CTD PMID:21335049 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VCAN versican increases expression ISO Isoproterenol results in increased expression of VCAN mRNA CTD PMID:20211217 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303 		JBrowse link
G VEGFA vascular endothelial growth factor A increases expression
decreases expression		 ISO
EXP		 Isoproterenol results in increased expression of VEGFA mRNA
Isoproterenol results in decreased expression of VEGF protein; Isoproterenol results in decreased expression of VEGFA mRNA		 CTD PMID:10788502 PMID:21335049 PMID:24286936 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VGLL3 vestigial like family member 3 increases expression ISO Isoproterenol results in increased expression of VGLL3 mRNA CTD PMID:20003209 NCBI chr 3:86,937,973...86,991,149
Ensembl chr 3:86,876,388...86,991,149 		JBrowse link
G VIM vimentin decreases expression ISO Isoproterenol results in decreased expression of VIM mRNA CTD PMID:21335049 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VWF von Willebrand factor increases expression ISO Isoproterenol results in increased expression of VWF mRNA CTD PMID:20003209 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770 		JBrowse link
G WDR3 WD repeat domain 3 increases expression ISO Isoproterenol results in increased expression of WDR3 mRNA CTD PMID:20003209 NCBI chr 1:117,929,739...117,966,543
Ensembl chr 1:117,929,720...117,966,543 		JBrowse link
G WFDC1 WAP four-disulfide core domain 1 decreases expression ISO Isoproterenol results in decreased expression of WFDC1 mRNA CTD PMID:20003209 NCBI chr16:84,294,878...84,329,844
Ensembl chr16:84,294,846...84,329,844 		JBrowse link
G XDH xanthine dehydrogenase increases expression
multiple interactions		 ISO Isoproterenol results in increased expression of XDH mRNA
[Isoproterenol co-treated with POSTN protein] results in decreased expression of XDH mRNA		 CTD PMID:20003209 PMID:30303030 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G XPA XPA, DNA damage recognition and repair factor increases expression ISO Isoproterenol results in increased expression of XPA mRNA CTD PMID:20003209 NCBI chr 9:97,654,398...97,697,340
Ensembl chr 9:97,674,909...97,697,340 		JBrowse link
G YPEL2 yippee like 2 increases expression ISO Isoproterenol results in increased expression of YPEL2 mRNA CTD PMID:20003209 NCBI chr17:59,331,655...59,401,729
Ensembl chr17:59,331,655...59,401,729 		JBrowse link
G YPEL3 yippee like 3 increases expression ISO Isoproterenol results in increased expression of YPEL3 mRNA CTD PMID:20003209 NCBI chr16:30,092,314...30,096,213
Ensembl chr16:30,092,314...30,096,915 		JBrowse link
G YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of YWHAG mRNA CTD PMID:30303030 NCBI chr 7:76,326,799...76,358,991
Ensembl chr 7:76,326,799...76,358,991 		JBrowse link
G YY1 YY1 transcription factor increases expression ISO Isoproterenol results in increased expression of YY1 mRNA CTD PMID:20003209 NCBI chr14:100,239,144...100,282,788
Ensembl chr14:100,238,298...100,282,788 		JBrowse link
G ZBTB11 zinc finger and BTB domain containing 11 increases expression ISO Isoproterenol results in increased expression of ZBTB11 mRNA CTD PMID:20003209 NCBI chr 3:101,648,889...101,677,132
Ensembl chr 3:101,648,889...101,677,135 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 increases expression ISO Isoproterenol results in increased expression of ZBTB16 mRNA CTD PMID:20003209 NCBI chr11:114,059,711...114,256,770
Ensembl chr11:114,059,041...114,256,765 		JBrowse link
G ZBTB44 zinc finger and BTB domain containing 44 increases expression ISO Isoproterenol results in increased expression of ZBTB44 mRNA CTD PMID:20003209 NCBI chr11:130,226,677...130,314,917
Ensembl chr11:130,226,677...130,314,917 		JBrowse link
G ZFAND5 zinc finger AN1-type containing 5 multiple interactions ISO [Isoproterenol co-treated with POSTN protein] results in decreased expression of ZFAND5 mRNA CTD PMID:30303030 NCBI chr 9:72,351,413...72,365,208
Ensembl chr 9:72,351,413...72,365,235 		JBrowse link
G ZMYM5 zinc finger MYM-type containing 5 increases expression ISO Isoproterenol results in increased expression of ZMYM5 mRNA CTD PMID:20003209 NCBI chr13:19,823,482...19,863,649
Ensembl chr13:19,823,482...19,863,649 		JBrowse link
G ZNF207 zinc finger protein 207 increases expression ISO Isoproterenol results in increased expression of ZFP207 mRNA CTD PMID:21335049 NCBI chr17:32,350,157...32,381,885
Ensembl chr17:32,350,132...32,381,885 		JBrowse link
G ZNF236 zinc finger protein 236 increases expression ISO Isoproterenol results in increased expression of ZFP236 mRNA CTD PMID:20003209 NCBI chr18:76,822,557...76,972,901
Ensembl chr18:76,822,557...76,972,901 		JBrowse link
G ZNF346 zinc finger protein 346 increases expression ISO Isoproterenol results in increased expression of ZFP346 mRNA CTD PMID:20003209 NCBI chr 5:177,022,696...177,081,189
Ensembl chr 5:177,022,696...177,081,189 		JBrowse link
G ZNF428 zinc finger protein 428 decreases expression ISO Isoproterenol results in decreased expression of ZFP428 mRNA CTD PMID:20003209 NCBI chr19:43,607,224...43,619,629
Ensembl chr19:43,607,224...43,619,629 		JBrowse link
G ZNF451 zinc finger protein 451 increases expression ISO Isoproterenol results in increased expression of ZFP451 mRNA CTD PMID:20003209 NCBI chr 6:57,090,188...57,170,305
Ensembl chr 6:57,086,844...57,170,305 		JBrowse link
G ZRANB3 zinc finger RANBP2-type containing 3 increases expression ISO Isoproterenol results in increased expression of ZRANB3 mRNA CTD PMID:20003209 NCBI chr 2:135,196,969...135,531,218
Ensembl chr 2:135,136,916...135,531,218 		JBrowse link
G ZW10 zw10 kinetochore protein increases expression ISO Isoproterenol results in increased expression of ZW10 mRNA CTD PMID:21335049 NCBI chr11:113,733,187...113,773,692
Ensembl chr11:113,733,187...113,773,735 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    role 25957
      application 25179
        pharmaceutical 24553
          drug 24550
            bronchodilator agent 3813
              isoprenaline 1165
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    main group molecular entity 25841
                      s-block molecular entity 25162
                        hydrogen molecular entity 24761
                          hydrides 22973
                            inorganic hydride 20500
                              pnictogen hydride 20441
                                nitrogen hydride 20219
                                  azane 19961
                                    ammonia 19960
                                      organic amino compound 19960
                                        secondary amino compound 6956
                                          isoprenaline 1165
paths to the root