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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoprenaline
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Accession:CHEBI:64317 term browser browse the term
Definition:A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Synonyms:exact_synonym: 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol
 related_synonym: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol;   1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol;   3,4-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol;   Formula=C11H17NO3;   InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3;   InChIKey=JWZZKOKVBUJMES-UHFFFAOYSA-N;   N-isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine;   N-isopropylnoradrenaline;   N-isopropylnorepinephrine;   SMILES=CC(C)NCC(O)c1ccc(O)c(O)c1;   alpha-(isopropylaminomethyl)protocatechuyl alcohol;   isoprenalina;   isoprenalinum;   isopropyl noradrenaline;   isoproterenol
 xref: CAS:7683-59-2;   DrugBank:DB01064;   Drug_Central:1499;   KEGG:C07056;   KEGG:D08090;   LINCS:LSM-4311
 xref_mesh: MESH:D007545
 xref: Patent:DE723278;   Patent:US2308232;   Reaxys:2213857;   Wikipedia:Isoprenaline


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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression ISO Isoproterenol results in increased expression of A2M mRNA CTD PMID:21335049 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Isoproterenol results in increased expression of ABCA1 mRNA CTD PMID:20003209 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Isoproterenol results in increased expression of ABCB1A mRNA CTD PMID:20003209 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression EXP
ISO
Isoproterenol results in decreased expression of ABCB4 mRNA CTD PMID:24286936 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of ABCC3 mRNA
Isoproterenol results in increased expression of ABCC3 mRNA
CTD PMID:21335049, PMID:24286936 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Isoproterenol results in increased expression of ABCC4 mRNA CTD PMID:20003209 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Isoproterenol results in increased expression of ABCG2 mRNA CTD PMID:20003209 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression EXP Isoproterenol results in increased expression of ABHD2 mRNA CTD PMID:20211217 NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Isoproterenol results in increased expression of ABHD4 mRNA CTD PMID:20003209 NCBI chr15:32,888,233...32,906,861
Ensembl chr15:32,894,938...32,906,850
JBrowse link
G Abi3 ABI family, member 3 increases expression ISO Isoproterenol results in increased expression of ABI3 mRNA CTD PMID:20003209 NCBI chr10:83,644,086...83,655,182
Ensembl chr10:83,644,086...83,655,182
JBrowse link
G Ablim3 actin binding LIM protein family, member 3 increases expression ISO Isoproterenol results in increased expression of ABLIM3 mRNA CTD PMID:20003209 NCBI chr18:57,126,534...57,245,965
Ensembl chr18:57,128,399...57,245,666
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases phosphorylation
increases phosphorylation
ISO
EXP
triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of ACACA protein]
Isoproterenol results in decreased phosphorylation of ACACA protein
CTD PMID:18390901, PMID:27491814 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain multiple interactions
decreases expression
EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]] CTD PMID:25045214 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases activity
multiple interactions
decreases expression
EXP Isoproterenol results in decreased activity of ACADM protein
Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]]
CTD PMID:19826179, PMID:25045214 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression ISO
EXP
Isoproterenol results in increased expression of ACE2 mRNA
Isoproterenol results in increased expression of ACE2 protein
CTD PMID:20003209, PMID:20409916 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression ISO Isoproterenol results in increased expression of ACER2 mRNA CTD PMID:20003209 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA] CTD PMID:10710348 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
decreases expression
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of ACTA2 mRNA]
Isoproterenol results in increased expression of ACTA2 mRNA; Isoproterenol results in increased expression of ACTA2 protein
CTD PMID:18089841, PMID:20003209, PMID:24945829, PMID:28526319 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta decreases expression ISO Isoproterenol results in decreased expression of ACTB mRNA CTD PMID:20003209 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression ISO Isoproterenol results in increased expression of ACTG2 mRNA CTD PMID:21335049 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Ada adenosine deaminase multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ADA mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO Isoproterenol results in increased expression of ADAM22 mRNA CTD PMID:20003209 NCBI chr 4:22,864,485...23,002,969
Ensembl chr 4:22,859,622...22,996,645
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP Isoproterenol results in increased expression of ADAM8 mRNA CTD PMID:20211217 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adamtsl2 ADAMTS-like 2 increases expression ISO Isoproterenol results in increased expression of ADAMTSL2 mRNA CTD PMID:20003209 NCBI chr 3:5,624,473...5,654,890
Ensembl chr 3:5,624,506...5,654,910
JBrowse link
G Adamtsl4 ADAMTS-like 4 increases expression ISO Isoproterenol results in increased expression of ADAMTSL4 mRNA CTD PMID:20003209 NCBI chr 2:197,803,572...197,815,058
Ensembl chr 2:197,803,584...197,814,808
JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance
multiple interactions
ISO ADCY5 protein results in increased susceptibility to Isoproterenol
[ADCY5 protein results in increased susceptibility to Isoproterenol] which results in decreased expression of SOD2 protein; SOD2 protein inhibits the reaction [ADCY5 protein results in increased susceptibility to Isoproterenol]
CTD PMID:12869393, PMID:23536361 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcy6 adenylate cyclase 6 affects response to substance ISO ADCY6 protein affects the susceptibility to Isoproterenol CTD PMID:12393090 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Add3 adducin 3 decreases expression ISO Isoproterenol results in decreased expression of ADD3 mRNA CTD PMID:21335049 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO Isoproterenol results in increased expression of ADGRD1 mRNA CTD PMID:20003209 NCBI chr12:31,134,806...31,249,594
Ensembl chr12:31,136,741...31,249,118
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression ISO Isoproterenol results in increased expression of ADGRF5 mRNA CTD PMID:20003209 NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566
JBrowse link
G Adgrl4 adhesion G protein-coupled receptor L4 increases expression ISO Isoproterenol results in increased expression of ADGRL4 mRNA CTD PMID:20003209 NCBI chr 2:256,609,787...256,724,642
Ensembl chr 2:256,609,787...256,724,641
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Isoproterenol results in increased expression of ADH1 mRNA CTD PMID:20003209 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adm adrenomedullin multiple interactions
increases expression
EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM mRNA; [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM protein; ADM protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]]; Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]
Isoproterenol results in increased expression of ADM mRNA; Isoproterenol results in increased expression of ADM protein
CTD PMID:12732346, PMID:17250927, PMID:17306419 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions
decreases expression
ISO ADRA1B protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRA1B mRNA
CTD PMID:12649302, PMID:20003209 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases expression
increases phosphorylation
increases activity
affects response to substance
increases uptake
ISO
EXP
[Isoproterenol binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; Atenolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; carvedilol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 12177 inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB1 protein results in increased abundance of Cyclic AMP]; Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]
Isoproterenol results in decreased expression of ADRB1 mRNA
Isoproterenol results in increased phosphorylation of ADRB1 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
ADRB1 protein polymorphism affects the susceptibility to Isoproterenol
Isoproterenol results in increased uptake of ADRB1 protein
ADRB1 protein promotes the reaction [Isoproterenol results in decreased expression of NPPA protein]; ADRB1 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; Isoproterenol binds to and results in increased activity of ADRB1 protein; Isoproterenol inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Metoprolol inhibits the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]
Isoproterenol results in decreased expression of ADRB1; Isoproterenol results in decreased expression of ADRB1 mRNA
CTD PMID:1312942, PMID:8096834, PMID:8723169, PMID:11159692, PMID:12761341, PMID:12963636, PMID:14502278, PMID:14730417, PMID:15627480, PMID:16731636, PMID:17200720, PMID:17350036, PMID:18194989, PMID:18378355, PMID:18787115, PMID:20003209 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases activity
affects expression
increases uptake
decreases expression
increases phosphorylation
increases expression
ISO
EXP
4-(1H-imidazol-4-ylmethyl)piperidine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Isoproterenol results in increased activity of ADRB2 protein] which results in increased chemical synthesis of Cyclic AMP; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol; Atenolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; clobenpropit promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Cobalt promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Histamine promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; Isoproterenol binds to and results in increased activity of ADRB2 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; Ketotifen inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Isoproterenol]; Propranolol inhibits the reaction [[Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]; Zinc promotes the reaction [Isoproterenol binds to and results in increased activity of ADRB2 protein]
Isoproterenol affects the expression of ADRB2 mRNA
Isoproterenol results in increased uptake of ADRB2 protein
[Isoproterenol results in increased activity of ADRB2 protein] which results in increased secretion of Histamine; ADRB2 protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]
Isoproterenol results in decreased expression of ADRB2; Isoproterenol results in decreased expression of ADRB2 mRNA
[GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein; ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased activity of ADRB2 protein]
Isoproterenol results in increased phosphorylation of ADRB2 protein
Isoproterenol results in increased expression of ADRB2 mRNA
CTD PMID:9875846, PMID:10226872, PMID:10516654, PMID:11164953, PMID:11752207, PMID:12920204, PMID:12963636, PMID:14730417, PMID:15178407, PMID:16036225, PMID:16980553, PMID:17196553, PMID:17350036, PMID:17925438, PMID:18378355, PMID:18820136, PMID:19483313, PMID:21177286, PMID:21629661, PMID:24705868, PMID:27825928 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases activity
increases expression
ISO
EXP
[Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Isoproterenol binds to and results in increased activity of ADRB3 protein; Isoproterenol inhibits the reaction [cyanopindolol binds to ADRB3 protein]; L 748,337 inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]
Isoproterenol results in increased expression of ADRB3 mRNA; Isoproterenol results in increased expression of ADRB3 protein
[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]; 3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased expression of ADRB3 protein]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 mRNA]; BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 protein]; Isoproterenol binds to and results in increased activity of ADRB3 protein
CTD PMID:1682311, PMID:7815362, PMID:11159692, PMID:14730417, PMID:15009959, PMID:17622774, PMID:18553954, PMID:18820136, PMID:20654104 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Aen apoptosis enhancing nuclease decreases expression ISO Isoproterenol results in decreased expression of AEN mRNA CTD PMID:20003209 NCBI chr 1:140,584,328...140,593,749
Ensembl chr 1:140,584,380...140,593,745
JBrowse link
G Agbl5 ATP/GTP binding protein-like 5 decreases expression ISO Isoproterenol results in decreased expression of AGBL5 mRNA CTD PMID:20003209 NCBI chr 6:26,837,299...26,857,234
Ensembl chr 6:26,838,036...26,855,658
JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
ISO
EXP
adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; ICI 118551 inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]; Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]; Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]]
Isoproterenol results in increased expression of AGT protein
AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA]; AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]; AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Losartan promotes the reaction [Isoproterenol results in increased expression of AGT protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; Quinapril promotes the reaction [Isoproterenol results in increased expression of AGT protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein]; trandolapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein]
Isoproterenol results in increased expression of AGT mRNA; Isoproterenol results in increased expression of AGT protein
Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein]
CTD PMID:1534315, PMID:1653766, PMID:7843740, PMID:11709406, PMID:16731636, PMID:19023134, PMID:19483313, PMID:20003209, PMID:20409916, PMID:24117263, PMID:27890915 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO Isoproterenol results in decreased expression of AGTR1A mRNA CTD PMID:17350036 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahcy adenosylhomocysteinase increases expression ISO Isoproterenol results in increased expression of AHCY mRNA CTD PMID:20003209 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression ISO Isoproterenol results in increased expression of AHNAK2 mRNA CTD PMID:20003209 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of AHR mRNA
Isoproterenol results in decreased expression of AHR mRNA
CTD PMID:24286936 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression ISO Isoproterenol results in increased expression of AHSG mRNA CTD PMID:20003209, PMID:21335049 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression ISO Isoproterenol results in decreased expression of AIF1 mRNA CTD PMID:20003209 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Isoproterenol results in decreased expression of AK4 mRNA CTD PMID:20003209 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akap1 A-kinase anchoring protein 1 decreases expression ISO Isoproterenol results in decreased expression of AKAP1 mRNA CTD PMID:20003209 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Akap13 A-kinase anchoring protein 13 increases expression ISO Isoproterenol results in increased expression of AKAP13 mRNA CTD PMID:20003209 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
decreases expression
ISO
EXP
Isoproterenol results in increased phosphorylation of AKT1 protein
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; [PDE3B protein co-treated with AKT1 protein] inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; Enalapril promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]
Isoproterenol results in decreased expression of AKT1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]; Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:15178407, PMID:15618457, PMID:15951400, PMID:16716347, PMID:17623046, PMID:18806606, PMID:19167487, PMID:20003209, PMID:31009642, PMID:32686902 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO Isoproterenol results in decreased expression of ALDH2 mRNA CTD PMID:20003209 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO Isoproterenol results in decreased expression of ALDH3A2 mRNA CTD PMID:21335049 NCBI chr10:47,525,486...47,546,535
Ensembl chr10:47,525,493...47,546,345
JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO Isoproterenol results in increased expression of ALPK2 mRNA CTD PMID:20003209 NCBI chr18:60,960,009...61,072,116
Ensembl chr18:60,960,662...61,057,365
JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions
increases expression
ISO Amphetamine promotes the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Chlorpromazine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA]; norfluoxetine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Amy1a amylase, alpha 1A multiple interactions EXP Atenolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein]; Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein; Propranolol inhibits the reaction [Isoproterenol results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:216,428,709...216,443,518
Ensembl chr 2:216,428,709...216,443,518
JBrowse link
G Ang angiogenin increases expression
multiple interactions
ISO Isoproterenol results in increased expression of ANG mRNA
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ANG mRNA]
CTD PMID:18089841, PMID:20003209 NCBI chr15:28,022,926...28,028,636 JBrowse link
G Angpt2 angiopoietin 2 increases expression EXP Isoproterenol results in increased expression of ANGPT2 mRNA CTD PMID:22908232 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL2 mRNA CTD PMID:20003209 NCBI chr 3:12,262,822...12,292,665
Ensembl chr 3:12,262,822...12,292,663
JBrowse link
G Angptl6 angiopoietin-like 6 decreases expression ISO Isoproterenol results in decreased expression of ANGPTL6 mRNA CTD PMID:21335049 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression ISO Isoproterenol results in decreased expression of ANP32A mRNA CTD PMID:20003209, PMID:21335049 NCBI chr 8:67,295,578...67,333,075
Ensembl chr 8:67,295,727...67,333,247
JBrowse link
G Anxa1 annexin A1 multiple interactions
increases expression
ISO ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]
Isoproterenol results in increased expression of ANXA1 mRNA
CTD PMID:16835395, PMID:20003209 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions
increases activity
EXP Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; H 35-25 inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; pimagedine inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein] CTD PMID:2860926, PMID:6218830 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Aoc3 amine oxidase, copper containing 3 increases expression ISO Isoproterenol results in increased expression of AOC3 mRNA CTD PMID:20003209 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Isoproterenol results in increased expression of AOX1 mRNA CTD PMID:20003209 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 increases expression ISO Isoproterenol results in increased expression of AP1B1 mRNA CTD PMID:21335049 NCBI chr14:85,230,652...85,281,806
Ensembl chr14:85,230,648...85,281,803
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Isoproterenol results in increased expression of APAF1 mRNA CTD PMID:24286936 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Isoproterenol results in increased expression of APEX1 mRNA CTD PMID:21335049 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apln apelin multiple interactions
decreases expression
EXP Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN mRNA]; Plant Extracts inhibits the reaction [Isoproterenol results in decreased expression of APLN protein]
Isoproterenol results in decreased expression of APLN mRNA; Isoproterenol results in decreased expression of APLN protein
CTD PMID:19960946 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G Apoa2 apolipoprotein A2 increases expression ISO Isoproterenol results in increased expression of APOA2 mRNA CTD PMID:21335049 NCBI chr13:89,596,872...89,598,805
Ensembl chr13:89,597,138...89,598,802
JBrowse link
G Apod apolipoprotein D increases expression ISO Isoproterenol results in increased expression of APOD mRNA CTD PMID:20003209 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 increases expression ISO Isoproterenol results in increased expression of APPBP2 mRNA CTD PMID:20003209 NCBI chr10:72,503,347...72,545,141
Ensembl chr10:72,503,347...72,545,141
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 increases expression ISO Isoproterenol results in increased expression of APPL2 mRNA CTD PMID:20003209 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Arf2 ADP-ribosylation factor 2 decreases expression ISO Isoproterenol results in decreased expression of ARF2 mRNA CTD PMID:20003209 NCBI chr10:92,018,562...92,040,335
Ensembl chr10:92,018,562...92,040,333
JBrowse link
G Arf4 ADP-ribosylation factor 4 increases expression ISO Isoproterenol results in increased expression of ARF4 mRNA CTD PMID:21335049 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G Arhgap12 Rho GTPase activating protein 12 increases expression ISO Isoproterenol results in increased expression of ARHGAP12 mRNA CTD PMID:20003209 NCBI chr17:54,280,815...54,394,716
Ensembl chr17:54,280,851...54,394,634
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Isoproterenol results in decreased expression of ARHGAP18 mRNA CTD PMID:20003209 NCBI chr 1:19,227,115...19,463,139
Ensembl chr 1:19,227,121...19,376,301
JBrowse link
G Arhgap20 Rho GTPase activating protein 20 increases expression ISO Isoproterenol results in increased expression of ARHGAP20 mRNA CTD PMID:20003209 NCBI chr 8:56,179,581...56,264,343
Ensembl chr 8:56,179,637...56,264,263
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 increases expression ISO Isoproterenol results in increased expression of ARHGAP24 mRNA CTD PMID:20003209 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arid4b AT-rich interaction domain 4B increases expression ISO Isoproterenol results in increased expression of ARID4B mRNA CTD PMID:20003209 NCBI chr17:53,831,353...53,955,897
Ensembl chr17:53,833,023...53,915,076
JBrowse link
G Arid5b AT-rich interaction domain 5B increases expression ISO Isoproterenol results in increased expression of ARID5B mRNA CTD PMID:20003209 NCBI chr20:21,713,900...21,881,193
Ensembl chr20:21,564,975...21,880,715
JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression ISO Isoproterenol results in increased expression of ARL4A mRNA CTD PMID:20003209 NCBI chr 6:59,945,926...59,950,586
Ensembl chr 6:59,948,577...59,950,586
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of ARNT2 mRNA
Isoproterenol results in increased expression of ARNT2 mRNA
CTD PMID:24286936 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like increases expression ISO Isoproterenol results in increased expression of ARNTL mRNA CTD PMID:20003209 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB1 protein] CTD PMID:18787115 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 affects localization
multiple interactions
ISO
EXP
Isoproterenol affects the localization of ARRB2 protein
ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Isoproterenol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; S-nitrosocysteine inhibits the reaction [Isoproterenol affects the localization of ARRB2 protein]
CTD PMID:17482545, PMID:17925438, PMID:18787115, PMID:21078978 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Isoproterenol results in increased expression of ARRDC2 mRNA CTD PMID:20003209 NCBI chr16:20,352,480...20,356,612
Ensembl chr16:20,352,480...20,356,612
JBrowse link
G Arrdc3 arrestin domain containing 3 increases expression ISO Isoproterenol results in increased expression of ARRDC3 mRNA CTD PMID:20003209 NCBI chr 2:8,732,907...8,745,445
Ensembl chr 2:8,732,932...8,743,069
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression ISO Isoproterenol results in decreased expression of ASAP1 mRNA CTD PMID:20003209 NCBI chr 7:104,670,076...104,951,090
Ensembl chr 7:104,669,672...104,801,045
JBrowse link
G Asb11 ankyrin repeat and SOCS box containing 11 increases expression ISO Isoproterenol results in increased expression of ASB11 mRNA CTD PMID:20003209 NCBI chr  X:31,758,294...31,781,863
Ensembl chr  X:31,700,633...31,780,425
JBrowse link
G Ascc3 activating signal cointegrator 1 complex subunit 3 increases expression ISO Isoproterenol results in increased expression of ASCC3 mRNA CTD PMID:20003209 NCBI chr20:55,253,670...55,557,249
Ensembl chr20:55,253,686...55,556,473
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Isoproterenol results in increased expression of ASNS mRNA CTD PMID:21335049, PMID:21823215 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asph aspartate-beta-hydroxylase decreases expression ISO Isoproterenol results in decreased expression of ASPH mRNA CTD PMID:20003209 NCBI chr 5:22,577,680...22,799,333
Ensembl chr 5:22,577,675...22,799,349
JBrowse link
G Aspn asporin increases expression ISO Isoproterenol results in increased expression of ASPN mRNA CTD PMID:20003209 NCBI chr17:14,655,958...14,681,355
Ensembl chr17:14,656,009...14,679,409
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Isoproterenol results in increased expression of ATAD2 mRNA CTD PMID:20003209 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of ATF2 protein] CTD PMID:18089841 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of ATF3 mRNA
Isoproterenol results in increased expression of ATF3 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of ATF3 protein]
CTD PMID:21823215, PMID:25136830 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) increases expression ISO Isoproterenol results in increased expression of ATP10D mRNA CTD PMID:20003209 NCBI chr14:38,475,956...38,575,937
Ensembl chr14:38,477,330...38,575,785
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression
EXP astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein]; astragaloside A inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 mRNA]; candesartan inhibits the reaction [Isoproterenol results in decreased expression of ATP2A2 protein]; Isoproterenol results in decreased expression of and results in decreased activity of ATP2A2 protein
Isoproterenol results in decreased expression of ATP2A2 mRNA; Isoproterenol results in decreased expression of ATP2A2 protein
CTD PMID:16723803, PMID:17509559 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha decreases expression ISO Isoproterenol results in decreased expression of ATP5A1 mRNA CTD PMID:20003209 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 decreases expression ISO Isoproterenol results in decreased expression of ATP6V1E1 mRNA CTD PMID:20003209 NCBI chr 4:153,351,434...153,373,558
Ensembl chr 4:153,351,421...153,373,649
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO Isoproterenol results in increased expression of ATP8B1 mRNA CTD PMID:20003209 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Atxn10 ataxin 10 increases expression ISO Isoproterenol results in increased expression of ATXN10 mRNA CTD PMID:20003209 NCBI chr 7:126,228,416...126,351,728
Ensembl chr 7:126,228,295...126,351,634
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 decreases expression ISO Isoproterenol results in decreased expression of AUTS2 mRNA CTD PMID:20003209 NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression ISO Isoproterenol results in decreased expression of BAG1 mRNA CTD PMID:21335049 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bak1 BCL2-antagonist/killer 1 decreases expression ISO Isoproterenol results in decreased expression of BAK1 mRNA CTD PMID:24286936 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression
ISO
EXP
Isoproterenol results in increased expression of BAX protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]; Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]; Apigenin inhibits the reaction [Isoproterenol results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX mRNA]]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of BAX protein]]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]; Tretinoin inhibits the reaction [Isoproterenol results in increased expression of BAX mRNA]
Isoproterenol results in decreased expression of BAX mRNA
Isoproterenol results in increased expression of BAX mRNA; Isoproterenol results in increased expression of BAX protein
CTD PMID:15052282, PMID:16116328, PMID:17961425, PMID:24286936, PMID:24954035, PMID:27491814, PMID:29414845, PMID:30152906, PMID:32007421 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Isoproterenol results in increased expression of BCAT1 mRNA CTD PMID:20211217, PMID:23558518, PMID:24286936 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases expression
ISO
EXP
Isoproterenol results in decreased expression of BCL2 protein
2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; [Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]; Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; echinocystic acid affects the reaction [Isoproterenol affects the expression of BCL2 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in decreased expression of BCL2 mRNA]]
Isoproterenol results in increased expression of BCL2 mRNA
Isoproterenol results in decreased expression of BCL2 mRNA; Isoproterenol results in decreased expression of BCL2 protein
CTD PMID:11218852, PMID:12791704, PMID:15052282, PMID:19573579, PMID:24954035, PMID:27491814, PMID:29414845, PMID:30152906, PMID:30623541, PMID:32007421 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of BCL2L1 mRNA
Isoproterenol results in decreased expression of BCL2L1 mRNA; Isoproterenol results in decreased expression of BCL2L1 protein
Isoproterenol results in increased expression of BCL2L1 mRNA alternative form; Isoproterenol results in increased expression of BCL2L1 protein; Isoproterenol results in increased expression of BCL2L1 protein alternative form
Apigenin inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 protein]; CGP 20712A inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; Metoprolol inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 protein]; Perindopril inhibits the reaction [Isoproterenol results in increased expression of BCL2L1 mRNA alternative form]; Thymol inhibits the reaction [Isoproterenol results in decreased expression of BCL2L1 mRNA]
CTD PMID:12738230, PMID:16116328, PMID:20003209, PMID:24286936, PMID:26996544, PMID:30152906 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO
EXP
Isoproterenol results in increased expression of BCL2L11 protein
Isoproterenol results in increased expression of BCL2L11 mRNA
CTD PMID:14996839, PMID:24286936 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 increases expression ISO Isoproterenol results in increased expression of BDH1 mRNA CTD PMID:20003209 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression ISO Isoproterenol results in increased expression of BICD1 mRNA CTD PMID:20003209 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G Bmf Bcl2 modifying factor increases expression EXP Isoproterenol results in increased expression of BMF mRNA CTD PMID:24286936 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bmp10 bone morphogenetic protein 10 multiple interactions
decreases response to substance
ISO BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; STAT3 protein affects the reaction [BMP10 protein results in decreased susceptibility to Isoproterenol]
BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]
CTD PMID:31712309 NCBI chr 4:119,224,906...119,230,534
Ensembl chr 4:119,225,040...119,230,728
JBrowse link
G Bnip1 BCL2 interacting protein 1 increases expression ISO Isoproterenol results in increased expression of BNIP1 protein CTD PMID:15052282 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Isoproterenol results in increased expression of BNIP3 mRNA CTD PMID:20003209 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bok BCL2 family apoptosis regulator BOK decreases expression ISO Isoproterenol results in decreased expression of BOK mRNA CTD PMID:21335049 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Brd4 bromodomain containing 4 decreases expression ISO Isoproterenol results in decreased expression of BRD4 mRNA CTD PMID:20003209 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 increases expression ISO Isoproterenol results in increased expression of BRWD1 mRNA CTD PMID:20003209 NCBI chr11:36,338,080...36,430,473
Ensembl chr11:36,337,635...36,430,413
JBrowse link
G Bsdc1 BSD domain containing 1 increases expression ISO Isoproterenol results in increased expression of BSDC1 mRNA CTD PMID:20003209 NCBI chr 5:147,661,618...147,689,766
Ensembl chr 5:147,661,618...147,689,759
JBrowse link
G C3 complement C3 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of C3 mRNA
Isoproterenol results in decreased expression of C3 mRNA
CTD PMID:20003209, PMID:24286936 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4b complement C4B (Chido blood group) increases expression ISO Isoproterenol results in increased expression of C4B mRNA CTD PMID:20003209 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G C9 complement C9 increases expression EXP Isoproterenol results in increased expression of C9 mRNA CTD PMID:24286936 NCBI chr 2:55,775,562...55,823,807
Ensembl chr 2:55,775,274...55,823,826
JBrowse link
G Ca4 carbonic anhydrase 4 increases expression ISO Isoproterenol results in increased expression of CAR4 mRNA CTD PMID:20003209 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Isoproterenol results in increased expression of CACNA1C mRNA CTD PMID:17526999 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cadm4 cell adhesion molecule 4 decreases expression ISO Isoproterenol results in decreased expression of CADM4 mRNA CTD PMID:20003209 NCBI chr 1:81,365,200...81,369,841
Ensembl chr 1:81,365,138...81,370,109
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP CALCA protein inhibits the reaction [Isoproterenol promotes the reaction [ADM protein results in increased abundance of Cyclic AMP]] CTD PMID:17306419 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calcrl calcitonin receptor like receptor multiple interactions
increases expression
EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of CALCRL mRNA
Isoproterenol results in increased expression of CALCRL mRNA; Isoproterenol results in increased expression of CALCRL protein
CTD PMID:16987513, PMID:17250927, PMID:17306419 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Isoproterenol results in decreased expression of CALM3 mRNA CTD PMID:20003209 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Calr calreticulin increases expression ISO Isoproterenol results in increased expression of CALR mRNA CTD PMID:21823215 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calr3 calreticulin 3 increases expression ISO Isoproterenol results in increased expression of CALR3 mRNA CTD PMID:20003209 NCBI chr16:19,097,391...19,124,062
Ensembl chr16:19,097,391...19,124,062
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO Isoproterenol results in increased expression of CAMK2B mRNA CTD PMID:20003209 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases phosphorylation EXP Isoproterenol results in decreased phosphorylation of CAMKK2 protein CTD PMID:27491814 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Capn1 calpain 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CAPN1 mRNA
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN1 mRNA]
CTD PMID:27527349 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn10 calpain 10 increases expression ISO Isoproterenol results in increased expression of CAPN10 mRNA CTD PMID:20003209 NCBI chr 9:100,104,000...100,112,833
Ensembl chr 9:100,104,000...100,112,832
JBrowse link
G Capn2 calpain 2 multiple interactions
increases expression
EXP Quercetin inhibits the reaction [Isoproterenol results in increased expression of CAPN2 mRNA] CTD PMID:27527349 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 increases expression ISO Isoproterenol results in increased expression of CARMIL1 mRNA CTD PMID:20003209 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Casp1 caspase 1 decreases expression
increases expression
ISO Isoproterenol results in decreased expression of CASP1 mRNA
Isoproterenol results in increased expression of CASP1 mRNA
CTD PMID:24286936 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp2 caspase 2 decreases expression
increases expression
EXP Isoproterenol results in decreased expression of CASP2 mRNA
Isoproterenol results in increased expression of CASP2 mRNA
CTD PMID:24286936 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity
ISO
EXP
Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein
Isoproterenol results in increased cleavage of CASP3 protein
Isoproterenol results in increased activity of CASP3 protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Progesterone inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP3 mRNA]
Isoproterenol results in increased expression of CASP3 mRNA; Isoproterenol results in increased expression of CASP3 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]; RAPGEF3 mutant form inhibits the reaction [Isoproterenol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]]; STAT3 protein affects the reaction [BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]]
CTD PMID:11218852, PMID:17136323, PMID:17961425, PMID:20726854, PMID:21745194, PMID:24286936, PMID:25794854, PMID:27491814, PMID:28266775, PMID:30152906, PMID:30623541, PMID:31712309 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
decreases expression
ISO
EXP
Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein
Isoproterenol results in decreased expression of CASP7 mRNA
CTD PMID:17136323, PMID:24286936 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CASP8 mRNA; Isoproterenol results in increased expression of CASP8 protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP8 protein]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP8 mRNA]
CTD PMID:25794854, PMID:26996544, PMID:30152906 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CASP9 mRNA; Isoproterenol results in increased expression of CASP9 protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CASP9 protein]; Thymol inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of CASP9 mRNA]
CTD PMID:24286936, PMID:25794854, PMID:26996544, PMID:30152906 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions
increases activity
increases expression
ISO
EXP
Isoproterenol results in decreased expression of CAT protein
Isoproterenol results in decreased activity of CAT protein
[Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; [Rosuvastatin Calcium co-treated with Isoproterenol] inhibits the reaction [Interleukin-6 results in increased expression of CAT protein]; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; Apigenin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Atenolol promotes the reaction [Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of CAT protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; Hesperidin inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Quercetin promotes the reaction [Atenolol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]]; Rosuvastatin Calcium inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Thymol inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]
Isoproterenol results in increased expression of CAT mRNA
CTD PMID:1840475, PMID:12708743, PMID:15740881, PMID:16584858, PMID:16697266, PMID:19146839, PMID:20003209, PMID:21322096, PMID:22391854, PMID:24201307, PMID:24954035, PMID:25537132, PMID:26721194, PMID:27527349, PMID:30152906, PMID:30623541, PMID:32007421 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO CAV1 protein promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein] CTD PMID:18820136 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cav3 caveolin 3 affects localization EXP Isoproterenol affects the localization of CAV3 protein CTD PMID:19299911 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Cblb Cbl proto-oncogene B increases expression ISO Isoproterenol results in increased expression of CBLB mRNA CTD PMID:20003209 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Ccdc58 coiled-coil domain containing 58 decreases expression ISO Isoproterenol results in decreased expression of CCDC58 mRNA CTD PMID:20003209 NCBI chr11:67,598,419...67,618,704
Ensembl chr11:67,598,419...67,618,704
JBrowse link
G Ccdc80 coiled-coil domain containing 80 increases expression ISO Isoproterenol results in increased expression of CCDC80 mRNA CTD PMID:20003209 NCBI chr11:60,645,660...60,679,249
Ensembl chr11:60,645,086...60,679,555
JBrowse link
G Ccdc85a coiled-coil domain containing 85A increases expression ISO Isoproterenol results in increased expression of CCDC85A mRNA CTD PMID:20003209 NCBI chr14:112,719,482...112,900,724
Ensembl chr14:112,719,482...112,946,875
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases secretion ISO Isoproterenol results in decreased secretion of CCL17 protein CTD PMID:12871855 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Isoproterenol results in increased expression of CCL2 mRNA CTD PMID:21823215 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
decreases expression
ISO Isoproterenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]
Isoproterenol results in increased expression of CCL3 protein
Isoproterenol results in decreased expression of CCL3 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]
CTD PMID:9863660, PMID:12538206, PMID:21335049, PMID:24286936 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 increases expression ISO Isoproterenol results in increased expression of CCL6 mRNA CTD PMID:20003209 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression
decreases expression
EXP
ISO
Isoproterenol results in increased expression of CCL7 mRNA
Isoproterenol results in decreased expression of CCL7 mRNA
CTD PMID:20211217, PMID:24286936 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Isoproterenol results in increased expression of CCN2 mRNA
Isoproterenol results in increased expression of CCN2 mRNA; Isoproterenol results in increased expression of CCN2 protein
Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA]; Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein]
Isoproterenol results in decreased expression of CCN2 mRNA
CTD PMID:20003209, PMID:24117263, PMID:24286936 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression
ISO Isoproterenol results in decreased expression of CCND1 mRNA
Isoproterenol results in increased expression of CCND1 mRNA
CTD PMID:20003209, PMID:21335049 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Isoproterenol results in increased expression of CCND3 mRNA CTD PMID:20003209 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CCNG2 mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression EXP Isoproterenol results in increased expression of CCR1 mRNA CTD PMID:20211217 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd14 CD14 molecule increases expression EXP
ISO
Isoproterenol results in increased expression of CD14 mRNA CTD PMID:20003209, PMID:20211217 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd163 CD163 molecule increases expression ISO Isoproterenol results in increased expression of CD163 mRNA CTD PMID:20003209 NCBI chr 4:156,752,063...156,785,467
Ensembl chr 4:156,752,082...156,785,467
JBrowse link
G Cd302 CD302 molecule increases expression ISO Isoproterenol results in increased expression of CD302 mRNA CTD PMID:20003209 NCBI chr 3:46,327,382...46,361,092
Ensembl chr 3:46,327,383...46,361,092
JBrowse link
G Cd36 CD36 molecule decreases expression EXP Isoproterenol results in decreased expression of CD36 protein CTD PMID:19826179 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Isoproterenol promotes the reaction [CD38 gene mutant form results in increased activity of REN protein] CTD PMID:23343681 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd74 CD74 molecule decreases expression ISO Isoproterenol results in decreased expression of CD74 mRNA CTD PMID:20003209 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cdc37l1 cell division cycle 37-like 1 increases expression ISO Isoproterenol results in increased expression of CDC37L1 mRNA CTD PMID:20003209 NCBI chr 1:247,110,147...247,139,113
Ensembl chr 1:247,107,397...247,138,155
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 decreases expression ISO Isoproterenol results in decreased expression of CDC42EP3 mRNA CTD PMID:20003209 NCBI chr 6:1,922,500...1,942,972
Ensembl chr 6:1,922,500...1,942,972
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression ISO Isoproterenol results in increased expression of CDC42EP4 mRNA CTD PMID:20003209 NCBI chr10:102,244,680...102,269,272
Ensembl chr10:102,244,681...102,269,272
JBrowse link
G Cdh11 cadherin 11 increases expression ISO Isoproterenol results in increased expression of CDH11 mRNA CTD PMID:20003209 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Cdh13 cadherin 13 decreases expression ISO Isoproterenol results in decreased expression of CDH13 mRNA CTD PMID:20003209 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Isoproterenol results in decreased expression of CDH2 mRNA CTD PMID:21335049 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions
ISO Isoproterenol results in increased expression of CDK1 mRNA; Isoproterenol results in increased expression of CDK1 protein
Atenolol inhibits the reaction [Isoproterenol results in increased expression of CDK1 mRNA]
CTD PMID:9593584 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CDKN1A mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdo1 cysteine dioxygenase type 1 increases expression ISO Isoproterenol results in increased expression of CDO1 mRNA CTD PMID:20003209 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Cds2 CDP-diacylglycerol synthase 2 increases expression ISO Isoproterenol results in increased expression of CDS2 mRNA CTD PMID:20003209 NCBI chr 3:124,896,657...124,935,221
Ensembl chr 3:124,896,618...124,935,226
JBrowse link
G Cdv3 CDV3 homolog increases expression ISO Isoproterenol results in increased expression of CDV3 mRNA CTD PMID:20003209 NCBI chr 8:111,837,232...111,850,393
Ensembl chr 8:111,839,091...111,850,393
JBrowse link
G Cdyl chromodomain Y-like increases expression ISO Isoproterenol results in increased expression of CDYL mRNA CTD PMID:20003209 NCBI chr17:29,672,925...29,895,416
Ensembl chr17:29,674,164...29,895,386
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Isoproterenol results in increased expression of CEBPD mRNA CTD PMID:20003209 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO Isoproterenol results in increased expression of CEBPG mRNA CTD PMID:20003209 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Cenpa centromere protein A decreases expression ISO Isoproterenol results in decreased expression of CENPA mRNA CTD PMID:20003209 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cep192 centrosomal protein 192 increases expression ISO Isoproterenol results in increased expression of CEP192 mRNA CTD PMID:20003209 NCBI chr18:63,572,084...63,656,302
Ensembl chr18:63,524,452...63,656,286
JBrowse link
G Cfh complement factor H increases expression ISO Isoproterenol results in increased expression of CFH mRNA CTD PMID:20003209 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity
ISO
EXP
[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein; Baclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Enkephalin, Leucine-2-Alanine promotes the reaction [Isoproterenol results in increased activity of CFTR protein]; Serotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein] CTD PMID:15020588, PMID:15039139, PMID:15151902 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP Isoproterenol results in increased expression of CH25H mRNA CTD PMID:20211217 NCBI chr 1:252,807,062...252,811,409
Ensembl chr 1:252,807,065...252,808,380
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Isoproterenol results in increased expression of CHAC1 mRNA CTD PMID:20003209 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chka choline kinase alpha increases expression ISO Isoproterenol results in increased expression of CHKA mRNA CTD PMID:20003209 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO Isoproterenol results in increased expression of and results in decreased degradation of CIDEC protein; KT 5720 inhibits the reaction [Isoproterenol results in increased expression of CIDEC protein] CTD PMID:21097823 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Cilp cartilage intermediate layer protein increases expression ISO Isoproterenol results in increased expression of CILP mRNA CTD PMID:20003209 NCBI chr 8:70,760,922...70,775,891
Ensembl chr 8:70,760,922...70,775,891
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of CIRBP mRNA CTD PMID:20003209 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO Isoproterenol results in increased expression of CITED2 mRNA CTD PMID:20003209 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression ISO Isoproterenol results in decreased expression of CITED4 mRNA CTD PMID:20003209 NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622
JBrowse link
G Ckb creatine kinase B multiple interactions EXP Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein] CTD PMID:19146839, PMID:22391854 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Ckm creatine kinase, M-type multiple interactions
increases secretion
EXP Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]]; Isoproterenol results in increased expression of [CKM protein binds to CKB protein]; Isoproterenol results in increased secretion of [CKM protein binds to CKB protein]; Quercetin inhibits the reaction [Isoproterenol results in increased secretion of CKM protein] CTD PMID:19146839, PMID:22391854, PMID:27527349 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO Isoproterenol results in increased expression of CLCA1 mRNA CTD PMID:20003209 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Isoproterenol results in decreased expression of CLCN3 mRNA CTD PMID:20003209 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Clec1a C-type lectin domain family 1, member A increases expression ISO Isoproterenol results in increased expression of CLEC1A mRNA CTD PMID:20003209 NCBI chr 4:163,191,503...163,214,678
Ensembl chr 4:163,191,503...163,214,678
JBrowse link
G Clec2d C-type lectin domain family 2, member D increases expression ISO Isoproterenol results in increased expression of CLEC2D mRNA CTD PMID:20003209 NCBI chr 4:162,278,252...162,302,881
Ensembl chr 4:162,292,305...162,302,156
JBrowse link
G Clec4d C-type lectin domain family 4, member D increases expression ISO Isoproterenol results in increased expression of CLEC4D mRNA CTD PMID:20003209 NCBI chr 4:156,253,084...156,264,766
Ensembl chr 4:156,253,079...156,264,769
JBrowse link
G Clic5 chloride intracellular channel 5 increases expression ISO Isoproterenol results in increased expression of CLIC5 mRNA CTD PMID:20003209 NCBI chr 9:19,121,676...19,372,673
Ensembl chr 9:19,121,677...19,372,673
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Isoproterenol results in increased expression of CLIP1 mRNA CTD PMID:20003209 NCBI chr12:38,345,203...38,452,650
Ensembl chr12:38,345,456...38,452,652
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 decreases expression ISO Isoproterenol results in decreased expression of CLIP4 mRNA CTD PMID:20003209 NCBI chr 6:23,222,020...23,316,962
Ensembl chr 6:23,222,021...23,316,962
JBrowse link
G Clpb caseinolytic mitochondrial matrix peptidase chaperone subunit B decreases expression ISO Isoproterenol results in decreased expression of CLPB mRNA CTD PMID:20003209 NCBI chr 1:166,739,372...166,866,095
Ensembl chr 1:166,739,532...166,866,107
JBrowse link
G Clu clusterin increases expression ISO Isoproterenol results in increased expression of CLU mRNA; Isoproterenol results in increased expression of CLU protein CTD PMID:15052282, PMID:20003209 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression ISO Isoproterenol results in increased expression of CNKSR1 mRNA CTD PMID:20003209 NCBI chr 5:152,447,348...152,458,005
Ensembl chr 5:152,446,845...152,458,023
JBrowse link
G Cnksr3 Cnksr family member 3 increases expression ISO Isoproterenol results in increased expression of CNKSR3 mRNA CTD PMID:20003209 NCBI chr 1:43,789,797...43,884,267
Ensembl chr 1:43,789,791...43,884,267
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Isoproterenol results in increased expression of COBLL1 mRNA CTD PMID:20003209 NCBI chr 3:51,137,104...51,298,956
Ensembl chr 3:51,137,076...51,297,852
JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL15A1 mRNA CTD PMID:20003209 NCBI chr 5:62,840,360...62,950,240 JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
EXP
ISO
manidipine inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL1A1 protein]
Isoproterenol results in increased expression of COL1A1 mRNA; Isoproterenol results in increased expression of COL1A1 protein
CTD PMID:9559417, PMID:24945829, PMID:26692091, PMID:28526319, PMID:31009642, PMID:31712309 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions
decreases expression
ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; Propranolol inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]
Isoproterenol results in decreased expression of COL2A1 mRNA; Isoproterenol results in decreased expression of COL2A1 protein
CTD PMID:21177286 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression
EXP
ISO
AGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; manidipine inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]
Isoproterenol results in increased expression of COL3A1 mRNA; Isoproterenol results in increased expression of COL3A1 protein
BMP10 protein inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]
CTD PMID:9559417, PMID:20409916, PMID:26692091, PMID:31009642, PMID:31712309 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Isoproterenol results in decreased expression of COL5A1 mRNA CTD PMID:21335049 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Isoproterenol results in increased expression of COL5A2 mRNA CTD PMID:20003209 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of Isoproterenol CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Corin corin, serine peptidase increases expression ISO Isoproterenol results in increased expression of CORIN mRNA CTD PMID:20003209 NCBI chr14:38,247,379...38,474,931
Ensembl chr14:38,247,791...38,473,648
JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression
decreases activity
EXP
ISO
allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of CP protein]
Isoproterenol results in increased expression of CP protein
Isoproterenol results in increased expression of CP mRNA
CTD PMID:1521861, PMID:15261977, PMID:20003209 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpne8 copine 8 increases expression ISO Isoproterenol results in increased expression of CPNE8 mRNA CTD PMID:20003209 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 increases expression ISO Isoproterenol results in increased expression of CPS1 mRNA CTD PMID:21335049 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions
decreases expression
EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]] CTD PMID:25045214 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of CPT2 mRNA
Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]]
CTD PMID:25045214 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Crb1 crumbs cell polarity complex component 1 increases expression ISO Isoproterenol results in increased expression of CRB1 mRNA CTD PMID:20003209 NCBI chr13:56,270,519...56,462,893
Ensembl chr13:56,270,781...56,462,834
JBrowse link
G Crbn cereblon increases expression ISO Isoproterenol results in increased expression of CRBN mRNA CTD PMID:20003209 NCBI chr 4:138,864,910...138,885,786
Ensembl chr 4:138,866,761...138,885,556
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
ISO
EXP
oxophenylarsine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]
CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; swietenine inhibits the reaction [Isoproterenol results in increased phosphorylation of CREB1 protein]
CTD PMID:12791704, PMID:17141199, PMID:21745194, PMID:32686902 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator multiple interactions
increases expression
affects localization
EXP CREM protein inhibits the reaction [Isoproterenol results in increased activity of CREB1 protein]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; CREM protein inhibits the reaction [Isoproterenol results in increased expression of NPPA protein]
Isoproterenol results in increased expression of CREM mRNA; Isoproterenol results in increased expression of CREM protein
Isoproterenol affects the localization of CREM protein
CTD PMID:12791704, PMID:20211217 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crlf1 cytokine receptor-like factor 1 increases expression ISO Isoproterenol results in increased expression of CRLF1 mRNA CTD PMID:20003209 NCBI chr16:20,675,042...20,686,365
Ensembl chr16:20,675,042...20,686,317
JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Isoproterenol inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cryba4 crystallin, beta A4 decreases expression ISO Isoproterenol results in decreased expression of CRYBA4 mRNA CTD PMID:20003209 NCBI chr12:50,407,843...50,414,434
Ensembl chr12:50,407,843...50,414,432
JBrowse link
G Cs citrate synthase decreases activity EXP Isoproterenol results in decreased activity of CS protein CTD PMID:27491814 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csdc2 cold shock domain containing C2 increases expression ISO Isoproterenol results in increased expression of CSDC2 mRNA CTD PMID:20003209 NCBI chr 7:123,168,811...123,183,336
Ensembl chr 7:123,168,811...123,183,335
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Isoproterenol results in increased expression of CSF2RB mRNA; Isoproterenol results in increased expression of CSF2RB2 mRNA CTD PMID:20003209 NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
JBrowse link
G Csk C-terminal Src kinase multiple interactions ISO CSK protein promotes the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Ctf1 cardiotrophin 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CTF1 mRNA; Isoproterenol results in increased expression of CTF1 protein
Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Spironolactone inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of CTF1 protein]
CTD PMID:23288202 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Isoproterenol co-treated with Caffeine] results in decreased expression of CTH mRNA CTD PMID:29447158 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression ISO Isoproterenol results in increased expression of CTHRC1 mRNA CTD PMID:20003209 NCBI chr 7:77,966,722...77,977,004
Ensembl chr 7:77,966,722...77,977,004
JBrowse link
G Ctnnal1 catenin alpha-like 1 increases expression ISO Isoproterenol results in increased expression of CTNNAL1 mRNA CTD PMID:20003209 NCBI chr 5:73,561,249...73,621,070
Ensembl chr 5:73,561,450...73,621,070
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Isoproterenol results in decreased expression of CTNNBIP1 mRNA CTD PMID:20003209 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027
JBrowse link
G Ctps2 CTP synthase 2 increases expression ISO Isoproterenol results in increased expression of CTPS2 mRNA CTD PMID:20003209 NCBI chr  X:33,383,087...33,522,852
Ensembl chr  X:33,383,087...33,522,836
JBrowse link
G Ctsb cathepsin B multiple interactions
increases activity
decreases expression
decreases activity
EXP
ISO
caffeic acid inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of CTSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSB protein]
Isoproterenol results in decreased expression of CTSB mRNA
CTD PMID:2015110, PMID:8534267, PMID:17188415, PMID:18294627, PMID:20391626, PMID:21335049 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D multiple interactions
affects activity
increases activity
decreases activity
increases expression
EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; alliin affects the reaction [Isoproterenol affects the activity of CTSD protein]; caffeic acid inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol affects the activity of CTSD protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of CTSD protein]; Methylprednisolone inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]; naringin inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Isoproterenol results in increased activity of CTSD protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of CTSD mRNA]
Isoproterenol results in increased expression of CTSD mRNA; Isoproterenol results in increased expression of CTSD protein
CTD PMID:894732, PMID:2015110, PMID:8534267, PMID:11829124, PMID:14499179, PMID:17045618, PMID:17182065, PMID:17188415, PMID:17623887, PMID:18294627, PMID:18424012, PMID:19172585, PMID:19641666, PMID:20391626, PMID:21762681 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsl cathepsin L increases expression ISO Isoproterenol results in increased expression of CTSL mRNA CTD PMID:20003209 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cul4b cullin 4B increases expression ISO Isoproterenol results in increased expression of CUL4B mRNA CTD PMID:20003209 NCBI chr  X:124,831,391...124,870,329
Ensembl chr  X:124,832,628...124,870,329
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression ISO Isoproterenol results in decreased expression of CUX2 mRNA CTD PMID:20003209 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cuzd1 CUB and zona pellucida-like domains 1 increases expression ISO Isoproterenol results in increased expression of CUZD1 mRNA CTD PMID:20003209 NCBI chr 1:201,881,846...201,894,970
Ensembl chr 1:201,881,836...201,894,775
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Isoproterenol results in increased expression of CXCL13 mRNA CTD PMID:20003209 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO Isoproterenol results in decreased expression of CXCL9 mRNA CTD PMID:20003209 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases activity ISO Isoproterenol results in increased activity of CXCR2 protein CTD PMID:15477226 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression ISO Isoproterenol results in decreased expression of CXXC5 mRNA CTD PMID:20003209 NCBI chr18:28,626,386...28,656,916
Ensembl chr18:28,653,592...28,656,937
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CYBA mRNA
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of CYBA mRNA]
CTD PMID:18594475 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cycs cytochrome c, somatic increases expression
multiple interactions
EXP Isoproterenol results in increased expression of CYCS protein
Apigenin inhibits the reaction [Isoproterenol results in increased expression of CYCS protein]
CTD PMID:30152906 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of CYP1A1 mRNA
Isoproterenol results in increased expression of CYP1A1 mRNA
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A1 protein]]
CTD PMID:15627480, PMID:15710352, PMID:18725507 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO
EXP
Isoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]; Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]
CTD PMID:15710352, PMID:18493746 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression EXP
ISO
Isoproterenol results in increased expression of CYP1B1 mRNA CTD PMID:18725507, PMID:20003209 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression ISO Isoproterenol results in decreased expression of CYP26B1 mRNA CTD PMID:20003209 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases activity ISO Isoproterenol results in increased activity of CYP2A5 protein CTD PMID:11162586 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO Isoproterenol results in increased expression of CYP2B10 mRNA CTD PMID:20003209 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP Isoproterenol results in decreased expression of CYP2C11 mRNA CTD PMID:18725507 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression EXP Isoproterenol affects the expression of CYP2E1 mRNA CTD PMID:18725507 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Isoproterenol results in increased expression of CYP4A3 mRNA CTD PMID:18725507 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 increases expression ISO Isoproterenol results in increased expression of CYSLTR1 mRNA CTD PMID:20003209 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cyss cystatin S multiple interactions
increases expression
EXP Reserpine inhibits the reaction [Isoproterenol results in increased expression of CYSS mRNA] CTD PMID:9447264 NCBI chr 3:144,427,430...144,431,768
Ensembl chr 3:144,427,207...144,431,806
JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP Isoproterenol results in decreased expression of DAG1 CTD PMID:18808529 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO Isoproterenol results in decreased expression of DBP mRNA CTD PMID:20003209 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Dcakd dephospho-CoA kinase domain containing decreases expression ISO Isoproterenol results in decreased expression of DCAKD mRNA CTD PMID:20003209 NCBI chr10:91,095,601...91,126,733
Ensembl chr10:91,095,545...91,122,018
JBrowse link
G Dcn decorin increases expression ISO Isoproterenol results in increased expression of DCN mRNA CTD PMID:20003209 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Isoproterenol results in increased expression of DCT mRNA CTD PMID:20003209 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Dctn5 dynactin subunit 5 increases expression ISO Isoproterenol results in increased expression of DCTN5 mRNA CTD PMID:21335049 NCBI chr 1:192,088,709...192,105,421
Ensembl chr 1:192,088,672...192,105,429
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of DDIT3 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of DDIT3 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of DDIT3 mRNA]]
CTD PMID:21823215, PMID:29414845 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of DDIT4 mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression ISO Isoproterenol results in increased expression of DDOST mRNA CTD PMID:21823215 NCBI chr 5:156,668,924...156,676,036
Ensembl chr 5:156,668,712...156,676,035
JBrowse link
G Defb1 defensin beta 1 decreases expression
increases expression
EXP Isoproterenol results in decreased expression of DEFB1 mRNA
Isoproterenol results in increased expression of DEFB1 mRNA
CTD PMID:24286936 NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176
JBrowse link
G Dennd4a DENN domain containing 4A increases expression ISO Isoproterenol results in increased expression of DENND4A mRNA CTD PMID:20003209 NCBI chr 8:70,293,355...70,406,675
Ensembl chr 8:70,317,586...70,406,751
JBrowse link
G Derl2 derlin 2 increases expression ISO Isoproterenol results in increased expression of DERL2 mRNA CTD PMID:21823215 NCBI chr10:57,641,682...57,653,554
Ensembl chr10:57,644,207...57,653,359
JBrowse link
G Derl3 derlin 3 decreases expression ISO Isoproterenol results in decreased expression of DERL3 mRNA CTD PMID:21823215 NCBI chr20:13,692,102...13,707,645
Ensembl chr20:13,704,314...13,706,205
JBrowse link
G Dffb DNA fragmentation factor subunit beta increases expression ISO Isoproterenol results in increased expression of DFFB mRNA CTD PMID:20003209 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Isoproterenol results in decreased expression of DHCR24 mRNA CTD PMID:20003209 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression ISO Isoproterenol results in decreased expression of DHRS3 mRNA CTD PMID:21335049 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO Isoproterenol results in decreased expression of DHRS7 mRNA CTD PMID:20003209, PMID:21335049 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Dhrs7c dehydrogenase/reductase 7C decreases expression ISO Isoproterenol results in decreased expression of DHRS7C mRNA CTD PMID:20003209 NCBI chr10:54,352,270...54,370,653
Ensembl chr10:54,352,270...54,370,653
JBrowse link
G Diaph2 diaphanous-related formin 2 increases expression ISO Isoproterenol results in increased expression of DIAPH2 mRNA CTD PMID:20003209 NCBI chr  X:99,722,910...100,363,228 JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression
increases activity
ISO
EXP
Isoproterenol results in increased expression of DIO2 mRNA
Isoproterenol results in increased activity of DIO2 protein
CTD PMID:15345674, PMID:20003209 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dixdc1 DIX domain containing 1 increases expression ISO Isoproterenol results in increased expression of DIXDC1 mRNA CTD PMID:20003209 NCBI chr 8:55,091,232...55,164,636
Ensembl chr 8:55,091,235...55,162,421
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Isoproterenol results in decreased expression of DLAT mRNA CTD PMID:21335049 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dmd dystrophin multiple interactions
decreases expression
ISO
EXP
DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of DMD
CTD PMID:18340010, PMID:18808529 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Isoproterenol results in increased expression of DNAJB11 mRNA CTD PMID:21823215 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Isoproterenol results in increased expression of DNAJB9 mRNA CTD PMID:21335049 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnm1l dynamin 1-like increases phosphorylation EXP Isoproterenol results in increased phosphorylation of DNM1L protein CTD PMID:27491814 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of DNMT3A mRNA
Isoproterenol results in increased expression of DNMT3A protein
CTD PMID:20003209, PMID:24945829 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta increases expression ISO Isoproterenol results in increased expression of DNMT3B mRNA CTD PMID:21335049 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dnttip2 deoxynucleotidyltransferase, terminal, interacting protein 2 increases expression ISO Isoproterenol results in increased expression of DNTTIP2 mRNA CTD PMID:20003209 NCBI chr 2:225,854,618...225,867,103
Ensembl chr 2:225,854,629...225,866,357
JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Isoproterenol results in increased expression of DOCK10 mRNA CTD PMID:20003209 NCBI chr 9:86,424,638...86,571,854
NCBI chr 9:86,312,470...86,423,054
Ensembl chr 9:86,312,501...86,571,870
JBrowse link
G Dock9 dedicator of cytokinesis 9 increases expression ISO Isoproterenol results in increased expression of DOCK9 mRNA CTD PMID:20003209 NCBI chr15:107,945,664...108,210,967
Ensembl chr15:107,945,664...108,210,826
JBrowse link
G Dpep1 dipeptidase 1 increases expression ISO Isoproterenol results in increased expression of DPEP1 mRNA CTD PMID:20003209 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Dpp7 dipeptidylpeptidase 7 increases expression ISO Isoproterenol results in increased expression of DPP7 mRNA CTD PMID:20003209 NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
JBrowse link
G Dsg2 desmoglein 2 decreases expression ISO Isoproterenol results in decreased expression of DSG2 mRNA CTD PMID:20003209 NCBI chr18:15,579,322...15,637,720
Ensembl chr18:15,579,315...15,637,715
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO Isoproterenol results in increased expression of DTX4 mRNA CTD PMID:20003209 NCBI chr 1:228,729,842...228,759,783
Ensembl chr 1:228,732,985...228,755,866
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; DUSP1 protein inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein] CTD PMID:21177286 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Isoproterenol results in increased expression of DUSP4 mRNA CTD PMID:20003209 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Dusp8 dual specificity phosphatase 8 decreases expression ISO Isoproterenol results in decreased expression of DUSP8 mRNA CTD PMID:20003209 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Dxo decapping exoribonuclease increases expression ISO Isoproterenol results in increased expression of DXO mRNA CTD PMID:21335049 NCBI chr20:4,517,307...4,519,391
Ensembl chr20:4,517,307...4,519,389
JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression ISO Isoproterenol results in increased expression of ECM1 mRNA CTD PMID:20003209 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Isoproterenol results in increased expression of EDEM1 mRNA CTD PMID:21335049, PMID:21823215 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases activity
increases expression
EXP Cyclosporine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; N-(1-methylethyl)-1,1,2-trimethylpropylamine inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]; Nifedipine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter]
Isoproterenol results in increased expression of EDN1 mRNA; Isoproterenol results in increased expression of EDN1 protein
CTD PMID:9861301, PMID:11435416, PMID:27174236, PMID:27890915 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of EDNRA mRNA
Isoproterenol results in increased expression of EDNRA mRNA; Isoproterenol results in increased expression of EDNRA protein
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRA protein]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of EDNRA mRNA]
CTD PMID:18594475, PMID:20003209, PMID:20307649, PMID:27174236 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of EDNRB mRNA]; natakalim inhibits the reaction [Isoproterenol results in increased expression of EDNRB protein]
Isoproterenol results in increased expression of EDNRB mRNA; Isoproterenol results in increased expression of EDNRB protein
CTD PMID:18594475, PMID:27174236 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1akmt1 EEF1A lysine methyltransferase 1 decreases expression ISO Isoproterenol results in decreased expression of EEF1AKMT1 mRNA CTD PMID:20003209 NCBI chr15:37,813,115...37,830,932
Ensembl chr15:37,813,115...37,831,031
JBrowse link
G Efhd2 EF-hand domain family, member D2 increases expression ISO Isoproterenol results in increased expression of EFHD2 mRNA CTD PMID:20003209 NCBI chr 5:160,407,777...160,423,811
Ensembl chr 5:160,407,778...160,423,811
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO Isoproterenol results in increased expression of EGFR mRNA
Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]
CTD PMID:18787115, PMID:20003209 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
decreases expression
ISO
EXP
EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA]
Isoproterenol results in increased expression of EGR1 protein
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]
Isoproterenol results in decreased expression of EGR1 mRNA
CTD PMID:10710348, PMID:15621046, PMID:20003209 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression ISO Isoproterenol results in increased expression of EIF1A mRNA CTD PMID:20003209, PMID:21335049 NCBI chr18:40,586,315...40,598,661
Ensembl chr18:40,586,315...40,597,671
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Isoproterenol results in increased expression of EIF2AK3 mRNA CTD PMID:21335049 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Isoproterenol results in decreased expression of EIF4A2 mRNA CTD PMID:21335049 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Isoproterenol results in decreased expression of EIF4E mRNA CTD PMID:20003209 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 increases expression ISO Isoproterenol results in increased expression of ELL2 mRNA CTD PMID:20003209 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Eln elastin multiple interactions
increases expression
EXP [Isoproterenol co-treated with Hydralazine] results in increased expression of ELN protein
Isoproterenol results in increased expression of ELN protein
CTD PMID:3446201 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 increases expression ISO Isoproterenol results in increased expression of ELOVL1 mRNA CTD PMID:20003209 NCBI chr 5:137,255,868...137,260,486
Ensembl chr 5:137,255,908...137,260,483
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO Isoproterenol results in increased expression of ENC1 mRNA CTD PMID:20003209 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eno1 enolase 1 decreases expression ISO Isoproterenol results in decreased expression of ENO1 mRNA CTD PMID:20003209 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP Isoproterenol results in decreased expression of ENPP1 protein CTD PMID:21414308 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Isoproterenol results in increased expression of ENTPD1 mRNA CTD PMID:20003209 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO Isoproterenol results in increased expression of EPS8 mRNA CTD PMID:20003209 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO Isoproterenol results in increased expression of ERP29 mRNA CTD PMID:21335049 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO Isoproterenol results in increased expression of ERRFI1 mRNA CTD PMID:20003209 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Etf1 eukaryotic translation termination factor 1 increases expression ISO Isoproterenol results in increased expression of ETF1 mRNA CTD PMID:20003209 NCBI chr18:27,698,693...27,725,694
Ensembl chr18:27,698,695...27,725,694
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Isoproterenol results in increased expression of EZH1 mRNA CTD PMID:20003209 NCBI chr10:89,104,026...89,139,978
Ensembl chr10:89,104,027...89,130,339
JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO Isoproterenol results in increased expression of F13A1 mRNA CTD PMID:20003209 NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of FABP3 protein
Isoproterenol results in decreased expression of FABP3 protein
CTD PMID:19549929, PMID:19826179, PMID:19854236, PMID:22878004 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Isoproterenol results in increased expression of FABP5 mRNA CTD PMID:21335049 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fam110d family with sequence similarity 110, member D increases expression ISO Isoproterenol results in increased expression of FAM110D mRNA CTD PMID:20003209 NCBI chr 5:152,470,898...152,473,903
Ensembl chr 5:152,470,905...152,473,868
JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression ISO Isoproterenol results in increased expression of FAM117B mRNA CTD PMID:20003209 NCBI chr 9:66,716,969...66,784,487
Ensembl chr 9:66,716,969...66,784,487
JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases expression ISO Isoproterenol results in increased expression of FARP1 mRNA CTD PMID:21335049 NCBI chr15:106,375,298...106,625,837
Ensembl chr15:106,434,177...106,625,837
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO
EXP
Isoproterenol results in increased expression of FAS mRNA
Apigenin inhibits the reaction [Isoproterenol results in increased expression of FAS protein]; Thymol inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]; Vanillic Acid inhibits the reaction [Isoproterenol results in increased expression of FAS mRNA]
Isoproterenol results in increased expression of FAS mRNA; Isoproterenol results in increased expression of FAS protein
CTD PMID:11218852, PMID:20003209, PMID:24286936, PMID:25794854, PMID:26996544, PMID:30152906 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression EXP Isoproterenol results in increased expression of FASLG protein CTD PMID:19001025 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fblim1 filamin binding LIM protein 1 decreases expression ISO Isoproterenol results in decreased expression of FBLIM1 mRNA CTD PMID:20003209 NCBI chr 5:160,122,466...160,158,921
Ensembl chr 5:160,122,425...160,158,386
JBrowse link
G Fbln2 fibulin 2 increases expression ISO Isoproterenol results in increased expression of FBLN2 mRNA CTD PMID:20003209 NCBI chr 4:122,835,237...122,895,127
Ensembl chr 4:122,835,436...122,895,121
JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 increases expression ISO Isoproterenol results in increased expression of FBXL20 mRNA CTD PMID:20003209 NCBI chr10:86,036,745...86,099,699
Ensembl chr10:86,043,235...86,098,694
JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO Isoproterenol results in increased expression of FBXO31 mRNA CTD PMID:20003209 NCBI chr19:53,487,610...53,625,673
Ensembl chr19:53,487,613...53,625,673
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Isoproterenol results in increased expression of FBXO32 mRNA CTD PMID:20003209 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Isoproterenol results in decreased expression of FBXO9 mRNA CTD PMID:21335049 NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 decreases expression ISO Isoproterenol results in decreased expression of FBXW7 mRNA CTD PMID:20003209 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression ISO Isoproterenol results in increased expression of FCGR3 mRNA CTD PMID:20003209 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb increases expression EXP
ISO
Isoproterenol results in increased expression of FCGR2B mRNA CTD PMID:20003209, PMID:20211217 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa increases expression ISO Isoproterenol results in increased expression of FCGR4 mRNA CTD PMID:20003209 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression ISO Isoproterenol results in increased expression of FEN1 mRNA CTD PMID:21335049 NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
JBrowse link
G Fetub fetuin B increases expression ISO Isoproterenol results in increased expression of FETUB mRNA CTD PMID:20003209 NCBI chr11:81,648,890...81,660,472
Ensembl chr11:81,648,885...81,660,395
JBrowse link
G Fgf16 fibroblast growth factor 16 decreases expression ISO Isoproterenol results in decreased expression of FGF16 mRNA CTD PMID:20003209 NCBI chr  X:76,786,728...76,796,311
Ensembl chr  X:76,786,466...76,797,069
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 increases expression ISO Isoproterenol results in increased expression of FGFR3 mRNA CTD PMID:20003209 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of FHL1 mRNA
Isoproterenol results in increased expression of FHL1 mRNA
CTD PMID:20211217, PMID:23558518, PMID:24286936 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression EXP Isoproterenol results in increased expression of FIS1 protein CTD PMID:27491814 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions
decreases expression
EXP 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; 1-(methanesulfonamido-1-naphthyloxy)-2-(N-(4-methane sulfonamidophenethyl)-N-acetamido)ethane inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein]
Isoproterenol results in decreased expression of FKBP1B mRNA; Isoproterenol results in decreased expression of FKBP1B protein
CTD PMID:20723002 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression ISO Isoproterenol results in decreased expression of FKBP4 mRNA CTD PMID:20003209 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression ISO Isoproterenol results in increased expression of FKBP5 mRNA CTD PMID:20003209 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO Isoproterenol results in increased expression of FLT1 mRNA CTD PMID:20003209 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression ISO Isoproterenol results in increased expression of FMO1 mRNA CTD PMID:20003209 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Isoproterenol results in increased expression of FMO2 mRNA CTD PMID:20003209 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of FN1 protein
Isoproterenol results in increased expression of FN1 protein
Quercetin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]; Rutin inhibits the reaction [Isoproterenol results in increased expression of FN1 protein]
Isoproterenol results in increased expression of FN1 mRNA
CTD PMID:11821714, PMID:20003209, PMID:24117263 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of FOS mRNA; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]
Isoproterenol results in increased expression of FOS mRNA; Isoproterenol results in increased expression of FOS protein
Isoproterenol results in increased expression of FOS; Isoproterenol results in increased expression of FOS mRNA
CREM protein inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]; Isoproterenol promotes the reaction [JUN protein binds to FOS protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of FOS]
CTD PMID:7544033, PMID:7905536, PMID:10710348, PMID:12791704, PMID:14764439, PMID:18089841, PMID:21177286 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Isoproterenol results in increased expression of FOSB CTD PMID:7905536 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of FOSL1 mRNA
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]
Isoproterenol results in increased expression of FOSL1 mRNA; Isoproterenol results in increased expression of FOSL1 protein
CTD PMID:20211217, PMID:21177286 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Isoproterenol results in increased expression of FOSL2 mRNA; Isoproterenol results in increased expression of FOSL2 protein
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA]
CTD PMID:21177286 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation ISO Isoproterenol results in increased phosphorylation of FOXO1 protein CTD PMID:15618457 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 increases expression ISO Isoproterenol results in increased expression of FOXO3 mRNA CTD PMID:20003209 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fry FRY microtubule binding protein increases expression ISO Isoproterenol results in increased expression of FRY mRNA CTD PMID:20003209 NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of FSHB protein] CTD PMID:20307649 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Isoproterenol results in increased expression of FTL1 mRNA CTD PMID:20003209 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fus FUS RNA binding protein decreases expression ISO Isoproterenol results in decreased expression of FUS mRNA CTD PMID:20003209 NCBI chr 1:199,412,805...199,426,705
Ensembl chr 1:199,412,834...199,426,702
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions
increases expression
EXP G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPA protein]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of NPPB protein]; Isoproterenol promotes the reaction [G3BP2 protein binds to NFKBIA protein]
Isoproterenol results in increased expression of G3BP2 mRNA; Isoproterenol results in increased expression of G3BP2 protein
CTD PMID:28816235 NCBI chr14:17,437,145...17,523,254
Ensembl chr14:17,492,081...17,520,792
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
increases activity
EXP Atenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]; Gallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Isoproterenol results in increased expression of GABARAPL1 mRNA CTD PMID:20003209 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Isoproterenol results in increased expression of GADD45G mRNA CTD PMID:21823215 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions
increases activity
increases expression
decreases activity
EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GAL protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GAL protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GAL mRNA] CTD PMID:2015110, PMID:11829124, PMID:14499179, PMID:17045618, PMID:17182065, PMID:17188415, PMID:19294532 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 increases expression ISO Isoproterenol results in increased expression of GALNT15 mRNA CTD PMID:20003209 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Gas5 growth arrest specific 5 increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of GAS5 mRNA
Isoproterenol results in decreased expression of GAS5 mRNA
CTD PMID:20003209, PMID:28526319 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gas6 growth arrest specific 6 multiple interactions
decreases expression
EXP natakalim inhibits the reaction [Isoproterenol results in decreased expression of GAS6 protein] CTD PMID:27890915 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gata4 GATA binding protein 4 multiple interactions ISO
EXP
[Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNA
Isoproterenol promotes the reaction [NFATC1 protein binds to GATA4 protein]
CTD PMID:10710348, PMID:11435416 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Isoproterenol results in decreased expression of GCLC mRNA CTD PMID:21335049 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
decreases expression
ISO Isoproterenol results in increased expression of GCLM mRNA
Isoproterenol results in decreased expression of GCLM mRNA
CTD PMID:20003209, PMID:21335049 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression ISO Isoproterenol results in increased expression of GCNT2 mRNA CTD PMID:20003209 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Gda guanine deaminase increases expression ISO Isoproterenol results in increased expression of GDA mRNA CTD PMID:20003209 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of GEM mRNA] CTD PMID:18089841 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 increases expression ISO Isoproterenol results in increased expression of GFPT2 mRNA CTD PMID:20003209 NCBI chr10:35,279,237...35,325,506
Ensembl chr10:35,279,236...35,325,508
JBrowse link
G Ggt5 gamma-glutamyltransferase 5 increases expression ISO Isoproterenol results in increased expression of GGT5 mRNA CTD PMID:20003209 NCBI chr20:13,988,444...14,001,296 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide increases expression EXP Isoproterenol results in increased expression of GHRL protein CTD PMID:20572026 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Ghsr growth hormone secretagogue receptor increases expression EXP Isoproterenol results in increased expression of GHSR mRNA; Isoproterenol results in increased expression of GHSR protein CTD PMID:20572026 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 increases expression ISO Isoproterenol results in increased expression of GIGYF2 mRNA CTD PMID:20003209 NCBI chr 9:94,425,191...94,550,431
Ensembl chr 9:94,425,252...94,550,431
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
decreases expression
increases expression
EXP
ISO
[Isoproterenol co-treated with Metoprolol] results in increased expression of GJA1 protein
Isoproterenol results in decreased expression of GJA1 mRNA
Isoproterenol results in increased expression of GJA1 mRNA; Isoproterenol results in increased expression of GJA1 protein
Doxycycline inhibits the reaction [Isoproterenol results in decreased expression of GJA1 mRNA]
CTD PMID:16352648, PMID:18089841, PMID:20003209, PMID:20215810 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gk glycerol kinase increases activity EXP Isoproterenol results in increased activity of GK protein CTD PMID:12736183 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions
affects activity
EXP caffeic acid inhibits the reaction [Isoproterenol affects the activity of GLB1 protein] CTD PMID:20391626 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939
JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Isoproterenol results in increased expression of GLUL mRNA CTD PMID:20003209 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gna15 G protein subunit alpha 15 multiple interactions
increases response to substance
ISO [GNA15 protein results in increased susceptibility to Isoproterenol] which results in increased activity of ADRB2 protein CTD PMID:9875846 NCBI chr 7:11,054,249...11,075,152
Ensembl chr 7:11,054,333...11,077,251
JBrowse link
G Gnal G protein subunit alpha L increases response to substance
multiple interactions
ISO GNAL protein results in increased susceptibility to Isoproterenol
Egtazic Acid inhibits the reaction [GNAL protein results in increased susceptibility to Isoproterenol]
CTD PMID:15598656 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
JBrowse link
G Gnas GNAS complex locus multiple interactions
increases response to substance
EXP
ISO
GNAS protein affects the susceptibility to [Potassium Chloride co-treated with Isoproterenol]; Isoproterenol affects the expression of and affects the localization of GNAS protein
Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to Isoproterenol]
CTD PMID:10696522, PMID:12376418, PMID:15598656 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gng2 G protein subunit gamma 2 increases expression ISO Isoproterenol results in increased expression of GNG2 mRNA CTD PMID:20003209 NCBI chr15:4,748,242...4,853,555
Ensembl chr15:4,850,122...4,853,555
JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions EXP [Isoproterenol co-treated with Atorvastatin] affects the localization of GNG3 protein CTD PMID:19136528 NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase increases expression ISO Isoproterenol results in increased expression of GNS mRNA CTD PMID:20003209 NCBI chr 7:63,467,027...63,501,054
Ensembl chr 7:63,467,216...63,499,353
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression EXP Isoproterenol results in decreased expression of GOT2 protein CTD PMID:19826179 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Isoproterenol results in decreased expression of GPAM mRNA CTD PMID:21335049 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO Isoproterenol results in decreased expression of GPCPD1 mRNA CTD PMID:20003209 NCBI chr 3:125,169,131...125,213,598
Ensembl chr 3:125,169,135...125,213,607
JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 increases expression ISO Isoproterenol results in increased expression of GPIHBP1 mRNA CTD PMID:20003209 NCBI chr 7:116,632,496...116,635,543
Ensembl chr 7:116,632,506...116,634,293
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Isoproterenol results in increased expression of GPNMB mRNA CTD PMID:20003209 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr160 G protein-coupled receptor 160 increases expression ISO Isoproterenol results in increased expression of GPR160 mRNA CTD PMID:20003209 NCBI chr 2:116,105,110...116,162,036
Ensembl chr 2:116,105,111...116,161,998
JBrowse link
G Gpr182 G protein-coupled receptor 182 increases expression ISO Isoproterenol results in increased expression of GPR182 mRNA CTD PMID:20003209 NCBI chr 7:71,044,786...71,048,713
Ensembl chr 7:71,045,543...71,048,383
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Isoproterenol results in increased expression of GPX3 mRNA CTD PMID:20003209 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression ISO Isoproterenol results in increased expression of GRINA mRNA CTD PMID:20003209 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 increases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of GRK2 mRNA
Isoproterenol results in increased expression of GRK2 mRNA; Isoproterenol results in increased expression of GRK2 protein
AGT affects the reaction [Isoproterenol results in decreased expression of GRK2 mRNA]
CTD PMID:9788834, PMID:16731636 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO Isoproterenol results in increased expression of GRK5 mRNA CTD PMID:20003209 NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
decreases phosphorylation
EXP
ISO
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Enalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]; plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:15951400, PMID:16716347, PMID:18806606, PMID:31009642 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
increases activity
decreases expression
EXP abana inhibits the reaction [Isoproterenol results in decreased expression of GSR]; allyl sulfide inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Catechin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; dicarbine inhibits the reaction [Isoproterenol results in increased activity of GSR protein]; Gallic Acid inhibits the reaction [Isoproterenol results in decreased expression of GSR protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]; Tretinoin inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]
Isoproterenol results in decreased expression of GSR; Isoproterenol results in decreased expression of GSR protein
CTD PMID:1840475, PMID:12557918, PMID:15261977, PMID:15740881, PMID:16697266, PMID:16757080, PMID:19146839, PMID:23261676, PMID:32007421 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases expression ISO Isoproterenol results in decreased expression of GSTO1 mRNA CTD PMID:21335049 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gtf2a1 general transcription factor 2A subunit 1 increases expression ISO Isoproterenol results in increased expression of GTF2A1 mRNA CTD PMID:20003209 NCBI chr 6:115,321,110...115,352,659
Ensembl chr 6:115,320,467...115,352,681
JBrowse link
G Gusb glucuronidase, beta multiple interactions
increases activity
decreases activity
increases expression
EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; [Nicorandil co-treated with Amlodipine] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; Betaine inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Curcumin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; mangiferin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of GUSB protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of GUSB protein]; S-allylcysteine inhibits the reaction [Isoproterenol results in increased expression of GUSB mRNA] CTD PMID:2015110, PMID:8534267, PMID:11829124, PMID:14499179, PMID:17045618, PMID:17182065, PMID:17188415, PMID:18294627, PMID:19172585, PMID:19294532, PMID:20391626, PMID:21762681 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F2 mRNA CTD PMID:20003209 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO Isoproterenol results in increased expression of H1F4 mRNA CTD PMID:20003209 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Isoproterenol results in increased expression of H2AX mRNA CTD PMID:21335049 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Haghl hydroxyacylglutathione hydrolase-like decreases expression ISO Isoproterenol results in decreased expression of HAGHL mRNA CTD PMID:20003209 NCBI chr10:15,152,736...15,157,221
Ensembl chr10:15,152,709...15,155,412
JBrowse link
G Hamp hepcidin antimicrobial peptide increases expression EXP
ISO
Isoproterenol results in increased expression of HAMP mRNA CTD PMID:20211217, PMID:21335049 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hap1 huntingtin-associated protein 1 increases expression ISO Isoproterenol results in increased expression of HAP1 mRNA CTD PMID:21335049 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210
JBrowse link
G Harbi1 harbinger transposase derived 1 increases expression ISO Isoproterenol results in increased expression of HARBI1 mRNA CTD PMID:20003209 NCBI chr 3:80,614,886...80,624,213
Ensembl chr 3:80,614,937...80,624,205
JBrowse link
G Hdac2 histone deacetylase 2 increases phosphorylation
multiple interactions
ISO
EXP
Isoproterenol results in increased phosphorylation of HDAC2 protein
plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of HDAC2 protein]
CTD PMID:31009642 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Heatr5b HEAT repeat containing 5B increases expression ISO Isoproterenol results in increased expression of HEATR5B mRNA CTD PMID:20003209 NCBI chr 6:1,330,314...1,410,339
Ensembl chr 6:1,330,314...1,410,339
JBrowse link
G Heca hdc homolog, cell cycle regulator increases expression ISO Isoproterenol results in increased expression of HECA mRNA CTD PMID:20003209 NCBI chr 1:13,036,909...13,050,644
Ensembl chr 1:13,036,909...13,050,644
JBrowse link
G Heph hephaestin increases expression ISO Isoproterenol results in increased expression of HEPH mRNA CTD PMID:20003209 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Isoproterenol results in increased expression of HERPUD1 mRNA CTD PMID:20003209 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Herpud2 HERPUD family member 2 increases expression ISO Isoproterenol results in increased expression of HERPUD2 mRNA CTD PMID:20003209 NCBI chr 8:26,266,571...26,311,528
Ensembl chr 8:26,266,760...26,311,350
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO Isoproterenol results in decreased expression of HES1 mRNA CTD PMID:20003209 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hexa hexosaminidase subunit alpha increases expression ISO Isoproterenol results in increased expression of HEXA mRNA CTD PMID:20003209 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hfe homeostatic iron regulator increases expression ISO Isoproterenol results in increased expression of HFE mRNA CTD PMID:20003209 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Isoproterenol results in decreased expression of HIF1A mRNA CTD PMID:20003209 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO Isoproterenol results in decreased expression of HIF1AN mRNA CTD PMID:24286936 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO
EXP
Isoproterenol results in increased expression of HIF3A mRNA CTD PMID:24286936 NCBI chr 1:78,976,318...78,997,869
Ensembl chr 1:78,976,318...78,997,869
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 increases expression ISO Isoproterenol results in increased expression of HIPK1 mRNA CTD PMID:20003209 NCBI chr 2:206,224,015...206,274,910
Ensembl chr 2:206,224,015...206,274,079
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 decreases expression ISO Isoproterenol results in decreased expression of HIPK2 mRNA CTD PMID:20003209 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 increases expression ISO Isoproterenol results in increased expression of HIPK3 mRNA CTD PMID:20003209 NCBI chr 3:94,349,778...94,419,185
Ensembl chr 3:94,352,969...94,419,048
JBrowse link
G Hk2 hexokinase 2 decreases expression ISO Isoproterenol results in decreased expression of HK2 mRNA CTD PMID:20003209 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression ISO Isoproterenol results in decreased expression of HLF mRNA CTD PMID:20003209 NCBI chr10:77,836,352...77,918,656
Ensembl chr10:77,840,568...77,918,191
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases activity
EXP 7-hydroxycoumarin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; alliin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein]; naringin inhibits the reaction [Isoproterenol results in increased activity of HMGCR protein] CTD PMID:16640830, PMID:16906524, PMID:19595682, PMID:26995004 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Isoproterenol results in increased expression of HMGCS1 mRNA CTD PMID:21335049 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]
Isoproterenol results in increased expression of HMOX1 mRNA; Isoproterenol results in increased expression of HMOX1 protein
Doxorubicin inhibits the reaction [Isoproterenol results in increased expression of HMOX1 mRNA]
CTD PMID:15179140, PMID:19483313, PMID:20003209, PMID:21823215, PMID:22908232, PMID:24929186 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 decreases expression ISO Isoproterenol results in decreased expression of HNRNPH3 mRNA CTD PMID:20003209 NCBI chr20:27,167,926...27,178,172
Ensembl chr20:27,169,267...27,216,941
JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R decreases expression ISO Isoproterenol results in decreased expression of HNRNPR mRNA CTD PMID:20003209 NCBI chr 5:154,668,194...154,699,967
Ensembl chr 5:154,668,179...154,699,966
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Isoproterenol results in increased expression of HOMER1 mRNA alternative form CTD PMID:16786172 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Hopx HOP homeobox decreases expression ISO Isoproterenol results in decreased expression of HOPX mRNA CTD PMID:20003209 NCBI chr14:33,354,803...33,362,547
Ensembl chr14:33,354,807...33,362,551
JBrowse link
G Hpca hippocalcin affects localization EXP Isoproterenol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 5:147,295,124...147,305,757
Ensembl chr 5:147,294,820...147,303,346
JBrowse link
G Hpse heparanase increases expression EXP Isoproterenol results in increased expression of HPSE protein CTD PMID:16327176 NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224
JBrowse link
G Hras HRas proto-oncogene, GTPase increases activity EXP Isoproterenol results in increased activity of HRAS protein CTD PMID:8484791 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Isoproterenol results in decreased expression of HS2ST1 mRNA CTD PMID:20003209 NCBI chr 2:250,467,428...250,600,517
Ensembl chr 2:250,467,429...250,600,517
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO Isoproterenol results in decreased expression of HSD3B1 mRNA CTD PMID:21335049
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression ISO Isoproterenol results in decreased expression of HSD3B2 mRNA CTD PMID:21335049 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Isoproterenol results in increased expression of HSP90AA1 mRNA CTD PMID:21335049 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Isoproterenol results in decreased expression of HSP90B1 mRNA CTD PMID:20003209 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression
decreases expression
ISO
EXP
Isoproterenol results in increased expression of HSPA1L mRNA
Isoproterenol results in decreased expression of HSPA1L mRNA
CTD PMID:20003209, PMID:24286936 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP
ISO
Isoproterenol results in increased expression of HSPA2 mRNA CTD PMID:20211217, PMID:24286936 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
decreases expression
ISO
EXP
Isoproterenol results in increased expression of HSPA5 mRNA
[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein; Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]; Plant Extracts inhibits the reaction [[Acrolein results in increased susceptibility to Isoproterenol] which results in increased expression of HSPA5 protein]; Plant Extracts inhibits the reaction [Acrolein promotes the reaction [Isoproterenol results in increased expression of HSPA5 mRNA]]
Isoproterenol results in decreased expression of HSPA5 mRNA
CTD PMID:21335049, PMID:24286936, PMID:29414845 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Isoproterenol results in decreased expression of HSPA8 mRNA CTD PMID:20003209, PMID:24286936 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression
EXP Curcumin promotes the reaction [Isoproterenol results in increased expression of HSPB1 protein]
Isoproterenol results in increased expression of HSP27 protein; Isoproterenol results in increased expression of HSPB1 protein
CTD PMID:10559386, PMID:20125031 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 increases expression EXP Isoproterenol results in increased expression of HSPB7 mRNA CTD PMID:24286936 NCBI chr 5:159,968,077...159,971,563
Ensembl chr 5:159,967,839...159,971,562
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression ISO Isoproterenol results in decreased expression of HSPG2 mRNA CTD PMID:20003209 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Isoproterenol results in increased expression of HSPH1 mRNA CTD PMID:21335049 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htra2 HtrA serine peptidase 2 decreases expression ISO Isoproterenol results in decreased expression of HTRA2 mRNA CTD PMID:21335049 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Htra3 HtrA serine peptidase 3 increases expression ISO Isoproterenol results in increased expression of HTRA3 mRNA CTD PMID:20003209 NCBI chr14:80,248,140...80,276,534
Ensembl chr14:80,248,140...80,276,534
JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression ISO Isoproterenol results in decreased expression of HYOU1 mRNA CTD PMID:20003209 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Isoproterenol results in increased expression of ICAM1 mRNA CTD PMID:20003209, PMID:21335049 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO Isoproterenol results in decreased expression of ID1 mRNA CTD PMID:21335049 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ier3 immediate early response 3 multiple interactions
affects response to substance
ISO IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]; Pertussis Toxin affects the reaction [IER3 protein affects the reaction [Isoproterenol results in increased abundance of Cyclic AMP]]; Pertussis Toxin affects the reaction [IER3 protein affects the susceptibility to Isoproterenol] CTD PMID:20713914 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifna1 interferon, alpha 1 decreases expression EXP Isoproterenol results in decreased expression of IFNA1 mRNA CTD PMID:24286936 NCBI chr 5:106,951,822...106,952,908
Ensembl chr 5:106,952,082...106,952,792
JBrowse link
G Ifng interferon gamma decreases secretion ISO Isoproterenol results in decreased secretion of IFNG protein CTD PMID:15342205 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr2 interferon gamma receptor 2 decreases expression ISO Isoproterenol results in decreased expression of IFNGR2 mRNA CTD PMID:20003209 NCBI chr11:31,694,339...31,712,611
Ensembl chr11:31,694,339...31,712,611
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO Isoproterenol results in increased expression of IFRD1 mRNA CTD PMID:20003209 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ift74 intraflagellar transport 74 increases expression ISO Isoproterenol results in increased expression of IFT74 mRNA CTD PMID:20003209 NCBI chr 5:113,579,065...113,682,485
Ensembl chr 5:113,592,919...113,682,484
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased expression of IGF1 mRNA
Isoproterenol results in increased expression of IGF1 mRNA; Isoproterenol results in increased expression of IGF1 protein
candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 mRNA]; candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 protein]
CTD PMID:10547078, PMID:20003209 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Isoproterenol results in increased expression of IGF1R mRNA CTD PMID:20003209 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression ISO Isoproterenol results in increased expression of IGF2BP2 mRNA CTD PMID:20003209 NCBI chr11:82,466,071...82,621,105
Ensembl chr11:82,466,071...82,621,079
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression
multiple interactions
EXP Isoproterenol results in decreased expression of IGFBP3
SI 27 inhibits the reaction [Isoproterenol results in decreased expression of IGFBP3]
CTD PMID:12883319 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
ISO
EXP
Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Quercetin inhibits the reaction [Isoproterenol results in decreased expression of IL10 protein]
CTD PMID:9038718, PMID:27527349 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A decreases expression EXP Isoproterenol results in decreased expression of IL12A protein CTD PMID:24286936 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B increases expression ISO Isoproterenol results in increased expression of IL12B protein CTD PMID:24286936 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A increases expression EXP Isoproterenol results in increased expression of IL17A protein CTD PMID:19909738 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17rd interleukin 17 receptor D increases expression ISO Isoproterenol results in increased expression of IL17RD mRNA CTD PMID:20003209 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
decreases expression
ISO
EXP
ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL18 protein; Isoproterenol results in increased expression of and results in increased stability of IL18 mRNA; Pertussis Toxin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA]; wortmannin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]
Isoproterenol results in decreased expression of IL18 mRNA
CTD PMID:15178407, PMID:21335049, PMID:24286936 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of IL1A mRNA
Isoproterenol results in increased expression of IL1A mRNA
CTD PMID:24286936 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression
ISO
EXP
SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL1B]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]
Isoproterenol results in decreased expression of IL1B mRNA; Isoproterenol results in decreased expression of IL1B protein
Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA
Isoproterenol results in increased expression of IL1B; Isoproterenol results in increased expression of IL1B mRNA; Isoproterenol results in increased expression of IL1B protein
Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]]
CTD PMID:9387890, PMID:12215284, PMID:15302781, PMID:18487443, PMID:19023134, PMID:19904010, PMID:21335049, PMID:21762681, PMID:24286936, PMID:25045214 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist affects response to substance ISO IL1RN protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of IL2 mRNA; Isoproterenol results in increased expression of IL2 protein
Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 mRNA]]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of IL2 protein]]
CTD PMID:25045214 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 decreases expression
increases expression
ISO
EXP
Isoproterenol results in decreased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 mRNA
Isoproterenol results in increased expression of IL4 protein
CTD PMID:24286936 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor increases expression ISO Isoproterenol results in increased expression of IL4RA mRNA CTD PMID:20003209 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il5ra interleukin 5 receptor subunit alpha affects response to substance ISO IL5RA protein affects the susceptibility to Isoproterenol CTD PMID:10487780 NCBI chr 4:138,796,165...138,834,164
Ensembl chr 4:138,795,327...138,830,117
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
increases secretion
decreases secretion
ISO
EXP
ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]; Genistein promotes the reaction [Isoproterenol results in increased secretion of IL6 protein]; Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; oxophenylarsine inhibits the reaction [Isoproterenol results in increased secretion of IL6 protein]; SB 206553 inhibits the reaction [Isoproterenol results in increased expression of IL6]; ZD 7155 inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
Isoproterenol results in decreased expression of IL6 mRNA
Apigenin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Enalapril inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Hesperidin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; ICI 118551 inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Isoproterenol inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Isoproterenol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Isoproterenol results in increased expression of and results in increased secretion of IL6 protein; Metformin inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL6 protein]; Metformin inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Isoproterenol results in increased expression of IL6 protein]
Isoproterenol results in increased expression of IL6; Isoproterenol results in increased expression of IL6 mRNA; Isoproterenol results in increased expression of IL6 protein
Isoproterenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:9038718, PMID:9688336, PMID:10525314, PMID:11406463, PMID:15302781, PMID:16835395, PMID:17141199, PMID:18487443, PMID:19023134, PMID:19909738, PMID:21088047, PMID:21762681, PMID:21823215, PMID:24286936, PMID:24842192, PMID:26277537, PMID:27527349, PMID:30152906, PMID:30623541, PMID:32007421 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il7 interleukin 7 increases expression ISO
EXP
Isoproterenol results in increased expression of IL7 protein CTD PMID:24286936 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Immt inner membrane mitochondrial protein decreases expression ISO Isoproterenol results in decreased expression of IMMT mRNA CTD PMID:20003209 NCBI chr 4:99,753,446...99,789,921
Ensembl chr 4:99,753,500...99,792,484
JBrowse link
G Inhbb inhibin subunit beta B increases expression ISO Isoproterenol results in increased expression of INHBB mRNA CTD PMID:20003209 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Ins2 insulin 2 multiple interactions
increases expression
affects expression
EXP INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]; OPC 3911 inhibits the reaction [INS protein inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein]]
Isoproterenol results in increased expression of INS protein
Isoproterenol affects the expression of INS protein
CTD PMID:1129332, PMID:1170870, PMID:19167487 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Ints3 integrator complex subunit 3 increases expression ISO Isoproterenol results in increased expression of INTS3 mRNA CTD PMID:20003209 NCBI chr 2:189,766,927...189,818,327
Ensembl chr 2:189,766,735...189,818,224
JBrowse link
G Ipo13 importin 13 decreases expression ISO Isoproterenol results in decreased expression of IPO13 mRNA CTD PMID:20003209 NCBI chr 5:136,728,744...136,749,187
Ensembl chr 5:136,728,740...136,748,980
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 increases expression ISO Isoproterenol results in increased expression of IRAK3 mRNA CTD PMID:20003209 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Irs1 insulin receptor substrate 1 increases expression ISO Isoproterenol results in increased expression of IRS1 mRNA CTD PMID:20003209 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO Isoproterenol results in decreased expression of IRX4 mRNA CTD PMID:20003209 NCBI chr 1:32,634,774...32,645,151
Ensembl chr 1:32,634,796...32,643,771
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Isoproterenol promotes the reaction [Theophylline inhibits the reaction [Platelet Activating Factor results in increased expression of ITGAM protein]] CTD PMID:9762784 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions
decreases expression
ISO
EXP
DMD gene mutant form promotes the reaction [ITGB1 gene affects the susceptibility to Isoproterenol]
Isoproterenol results in decreased expression of ITGB1
CTD PMID:18340010, PMID:18808529 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgbl1 integrin subunit beta like 1 increases expression ISO Isoproterenol results in increased expression of ITGBL1 mRNA CTD PMID:20003209 NCBI chr15:110,114,148...110,378,970
Ensembl chr15:110,114,148...110,378,969
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression ISO Isoproterenol results in increased expression of ITIH3 mRNA CTD PMID:20003209 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression ISO Isoproterenol results in increased expression of ITIH4 mRNA CTD PMID:20003209 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Itk IL2-inducible T-cell kinase decreases expression ISO Isoproterenol results in decreased expression of ITK mRNA CTD PMID:20003209 NCBI chr10:31,431,820...31,493,413
Ensembl chr10:31,431,809...31,493,419
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B decreases expression ISO Isoproterenol results in decreased expression of ITPKB mRNA CTD PMID:20003209 NCBI chr13:98,615,287...98,710,426
Ensembl chr13:98,615,287...98,708,149
JBrowse link
G Jade2 jade family PHD finger 2 increases expression ISO Isoproterenol results in increased expression of JADE2 mRNA CTD PMID:20003209 NCBI chr10:37,269,132...37,315,638
Ensembl chr10:37,270,183...37,311,625
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 decreases expression ISO Isoproterenol results in decreased expression of JARID2 mRNA CTD PMID:20003209 NCBI chr17:20,183,440...20,365,219
Ensembl chr17:20,184,245...20,364,714
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]; [Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]
Isoproterenol results in increased expression of JUN mRNA; Isoproterenol results in increased expression of JUN protein
Isoproterenol promotes the reaction [JUN protein binds to FOS protein]
CTD PMID:10710348, PMID:14764439, PMID:21177286 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Isoproterenol results in increased expression of JUNB
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 mRNA]; JUNB protein promotes the reaction [Isoproterenol results in decreased expression of SOX6 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; U 0126 inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]
Isoproterenol results in increased expression of JUNB mRNA; Isoproterenol results in increased expression of JUNB protein
CTD PMID:7905536, PMID:21177286 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 increases expression ISO Isoproterenol results in increased expression of KANK3 mRNA CTD PMID:20003209 NCBI chr 7:18,668,665...18,681,945
Ensembl chr 7:18,668,692...18,681,939
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 increases expression ISO Isoproterenol results in increased expression of KCNA5 mRNA CTD PMID:20003209 NCBI chr 4:159,077,195...159,079,003
Ensembl chr 4:159,077,195...159,079,003
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Isoproterenol results in decreased expression of KCNB1 mRNA CTD PMID:20003209 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Isoproterenol results in decreased expression of KCND2 mRNA CTD PMID:20003209 NCBI chr 4:48,309,283...48,816,804 JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions
decreases expression
ISO Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]]
Isoproterenol results in decreased expression of KCNE1 mRNA
CTD PMID:16909339, PMID:20003209 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 increases expression ISO Isoproterenol results in increased expression of KCNH6 mRNA CTD PMID:20003209 NCBI chr10:94,207,336...94,228,236
Ensembl chr10:94,207,314...94,228,236
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]] CTD PMID:16909339 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kcnt2 potassium sodium-activated channel subfamily T member 2 increases expression ISO Isoproterenol results in increased expression of KCNT2 mRNA CTD PMID:20003209 NCBI chr13:57,130,855...57,520,263
Ensembl chr13:57,131,395...57,521,836
JBrowse link
G Kdm6b lysine demethylase 6B decreases expression ISO Isoproterenol results in decreased expression of KDM6B mRNA CTD PMID:20003209 NCBI chr10:56,000,494...56,009,582
Ensembl chr10:56,001,799...56,008,885
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO Isoproterenol results in decreased expression of KDR mRNA CTD PMID:20003209 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kif1b kinesin family member 1B decreases expression ISO Isoproterenol results in decreased expression of KIF1B mRNA CTD PMID:20003209 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Klf15 Kruppel-like factor 15 increases expression ISO Isoproterenol results in increased expression of KLF15 mRNA CTD PMID:20003209 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
JBrowse link
G Klf3 Kruppel like factor 3 increases expression ISO Isoproterenol results in increased expression of KLF3 mRNA CTD PMID:20003209 NCBI chr14:45,142,769...45,173,753
Ensembl chr14:45,142,769...45,165,207
JBrowse link
G Klhdc8a kelch domain containing 8A decreases expression ISO Isoproterenol results in decreased expression of KLHDC8A mRNA CTD PMID:20003209 NCBI chr13:49,074,644...49,082,729
Ensembl chr13:49,074,644...49,082,729
JBrowse link
G Klhl2 kelch-like family member 2 increases expression ISO Isoproterenol results in increased expression of KLHL2 mRNA CTD PMID:20003209 NCBI chr16:26,755,246...26,852,134
Ensembl chr16:26,739,389...26,852,179
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Isoproterenol results in increased expression of KLHL24 mRNA CTD PMID:20003209 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Klhl40 kelch-like family member 40 increases expression EXP Isoproterenol results in increased expression of KLHL40 mRNA CTD PMID:20211217 NCBI chr 8:130,416,265...130,421,871
Ensembl chr 8:130,416,355...130,421,871
JBrowse link
G Klhl41 kelch-like family member 41 increases expression EXP Isoproterenol results in increased expression of KLHL41 mRNA CTD PMID:20211217 NCBI chr 3:55,910,177...55,923,303
Ensembl chr 3:55,910,177...55,923,303
JBrowse link
G Klhl7 kelch-like family member 7 increases expression ISO Isoproterenol results in increased expression of KLHL7 mRNA CTD PMID:20003209 NCBI chr 4:7,532,881...7,582,032
Ensembl chr 4:7,532,889...7,582,207
JBrowse link
G Kmt5a lysine methyltransferase 5A decreases expression ISO Isoproterenol results in decreased expression of KMT5A mRNA CTD PMID:20003209 NCBI chr12:37,558,150...37,581,183
Ensembl chr12:37,559,770...37,574,750
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression ISO Isoproterenol results in increased expression of KRAS mRNA CTD PMID:21335049 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt18 keratin 18 increases expression ISO Isoproterenol results in increased expression of KRT18 mRNA CTD PMID:21335049 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt222 keratin 222 decreases expression ISO Isoproterenol results in decreased expression of KRT222 mRNA CTD PMID:20003209 NCBI chr10:87,143,200...87,154,142
Ensembl chr10:87,142,116...87,153,982
JBrowse link
G Ky kyphoscoliosis peptidase decreases expression ISO Isoproterenol results in decreased expression of KY mRNA CTD PMID:20003209 NCBI chr 8:110,982,777...111,022,666
Ensembl chr 8:110,982,777...111,022,385
JBrowse link
G Lama2 laminin subunit alpha 2 decreases expression EXP Isoproterenol results in decreased expression of LAMA2 CTD PMID:18808529 NCBI chr 1:18,491,264...19,143,486
Ensembl chr 1:18,491,384...19,143,269
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO Isoproterenol results in decreased expression of LAMB1 mRNA CTD PMID:20003209 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lbh LBH regulator of WNT signaling pathway decreases expression ISO Isoproterenol results in decreased expression of LBH mRNA CTD PMID:20003209 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression ISO Isoproterenol results in increased expression of LBP mRNA CTD PMID:20003209, PMID:21335049 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions
decreases activity
EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; alliin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; Desmodium gangeticum extract inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; epigallocatechin gallate inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LCAT protein] CTD PMID:15740881, PMID:16640830, PMID:16906524, PMID:19595682, PMID:20024955 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of LCN2 mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions
increases expression
increases secretion
EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHA protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHA protein] CTD PMID:17188415, PMID:19146839, PMID:21322096, PMID:21472895, PMID:21671307 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B multiple interactions
increases expression
increases secretion
EXP [Quercetin co-treated with alpha-Tocopherol] inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; caffeic acid inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]; Gallic Acid inhibits the reaction [Isoproterenol results in increased secretion of LDHB protein]; naringin inhibits the reaction [Isoproterenol results in increased expression of LDHB protein] CTD PMID:17188415, PMID:19146839, PMID:21322096, PMID:21472895, PMID:21671307 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lep leptin decreases secretion
increases secretion
increases expression
multiple interactions
ISO
EXP
Isoproterenol results in decreased secretion of LEP protein
Isoproterenol results in increased secretion of LEP protein
Isoproterenol results in increased expression of LEP protein
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEP protein]
Propranolol inhibits the reaction [Isoproterenol results in decreased secretion of LEP protein]
CTD PMID:11022189, PMID:20307649, PMID:25111128 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor multiple interactions
increases expression
EXP CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR mRNA]; CPU0213 inhibits the reaction [Isoproterenol results in increased expression of LEPR protein]
Isoproterenol results in increased expression of LEPR mRNA; Isoproterenol results in increased expression of LEPR protein
CTD PMID:20307649 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals3 galectin 3 increases expression ISO Isoproterenol results in increased expression of LGALS3 mRNA CTD PMID:20003209 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 decreases expression ISO Isoproterenol results in decreased expression of LGI1 mRNA CTD PMID:20003209 NCBI chr 1:256,955,944...256,996,835
Ensembl chr 1:256,955,652...256,999,253
JBrowse link
G Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 decreases expression ISO Isoproterenol results in decreased expression of LGR6 mRNA CTD PMID:20003209 NCBI chr13:51,811,904...51,931,193
Ensembl chr13:51,815,215...51,930,972
JBrowse link
G Limd1 LIM domains containing 1 increases expression ISO Isoproterenol results in increased expression of LIMD1 mRNA CTD PMID:20003209 NCBI chr 8:132,553,218...132,598,826
Ensembl chr 8:132,553,218...132,598,812
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Isoproterenol results in increased expression of LIN7A mRNA CTD PMID:20003209 NCBI chr 7:49,429,613...49,627,835
Ensembl chr 7:49,385,705...49,656,856
JBrowse link
G Lipe lipase E, hormone sensitive type increases phosphorylation
affects localization
multiple interactions
increases activity
ISO
EXP
Isoproterenol results in increased phosphorylation of LIPE protein
Isoproterenol affects the localization of LIPE protein
Papaverine inhibits the reaction [Isoproterenol affects the localization of LIPE protein]; Papaverine inhibits the reaction [Isoproterenol results in increased activity of LIPE protein]
Sirolimus promotes the reaction [Isoproterenol results in increased phosphorylation of LIPE protein]
CTD PMID:10894095, PMID:11160373, PMID:21042876 NCBI chr 1:82,248,031...82,266,727
Ensembl chr 1:82,248,046...82,266,727
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Isoproterenol results in increased expression of LITAF mRNA CTD PMID:20003209, PMID:21335049 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lman1 lectin, mannose-binding, 1 increases expression ISO Isoproterenol results in increased expression of LMAN1 mRNA CTD PMID:21823215 NCBI chr18:61,683,377...61,707,344
Ensembl chr18:61,685,117...61,707,317
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Isoproterenol results in increased expression of LMCD1 mRNA CTD PMID:20211217, PMID:23558518 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Lmod3 leiomodin 3 decreases expression ISO Isoproterenol results in decreased expression of LMOD3 mRNA CTD PMID:20003209 NCBI chr 4:129,604,378...129,619,136
Ensembl chr 4:129,604,267...129,619,142
JBrowse link
G LOC100909593 class II histocompatibility antigen, M alpha chain-like decreases expression ISO Isoproterenol results in decreased expression of H2-DMA mRNA CTD PMID:20003209 NCBI chr20:3,935,501...3,938,915 JBrowse link
G LOC103689977 caspase-6 decreases expression ISO Isoproterenol results in decreased expression of CASP6 mRNA CTD PMID:21335049 NCBI chr 2:230,186,170...230,198,555
Ensembl chr 2:230,186,198...230,198,555
JBrowse link
G LOC103690086 uncharacterized LOC103690086 increases expression ISO Isoproterenol results in increased expression of GBP6 mRNA CTD PMID:20003209 NCBI chr14:5,642,357...5,646,406 JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO Isoproterenol results in increased expression of LONRF3 mRNA CTD PMID:20003209 NCBI chr  X:122,937,987...122,973,289
Ensembl chr  X:122,938,009...122,973,321
JBrowse link
G Lox lysyl oxidase increases expression ISO Isoproterenol results in increased expression of LOX mRNA CTD PMID:20003209 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpl lipoprotein lipase multiple interactions
decreases expression
increases expression
decreases activity
EXP
ISO
cirazoline promotes the reaction [Isoproterenol results in increased expression of LPL mRNA]; naringin inhibits the reaction [Isoproterenol results in decreased activity of LPL protein]
Isoproterenol results in decreased expression of LPL mRNA
CTD PMID:9032464, PMID:16906524, PMID:21335049 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression ISO Isoproterenol results in decreased expression of LRAT mRNA CTD PMID:20003209 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression ISO Isoproterenol results in increased expression of LRG1 mRNA CTD PMID:20003209 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lrrc52 leucine rich repeat containing 52 increases expression ISO Isoproterenol results in increased expression of LRRC52 mRNA CTD PMID:20003209 NCBI chr13:85,672,013...85,695,421
Ensembl chr13:85,672,014...85,695,421
JBrowse link
G Lrrc58 leucine rich repeat containing 58 increases expression ISO Isoproterenol results in increased expression of LRRC58 mRNA CTD PMID:20003209 NCBI chr11:65,747,235...65,759,558
Ensembl chr11:65,747,036...65,759,581
JBrowse link
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C increases expression ISO Isoproterenol results in increased expression of LRRC8C mRNA CTD PMID:20003209 NCBI chr14:5,283,655...5,378,738
Ensembl chr14:5,283,647...5,378,726
JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor increases expression ISO Isoproterenol results in increased expression of LSM14A mRNA CTD PMID:20003209 NCBI chr 1:90,200,866...90,246,292
Ensembl chr 1:90,200,876...90,246,297
JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Isoproterenol results in decreased expression of LSM3 mRNA CTD PMID:20003209 NCBI chr 4:123,162,086...123,168,330
Ensembl chr 4:123,162,086...123,168,330
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 increases expression ISO Isoproterenol results in increased expression of LTBP2 mRNA CTD PMID:20003209 NCBI chr 6:108,500,114...108,596,653
Ensembl chr 6:108,500,112...108,596,569
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 increases expression ISO Isoproterenol results in increased expression of LYVE1 mRNA CTD PMID:20003209 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Isoproterenol results in increased expression of MAFF mRNA CTD PMID:20003209 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 increases expression ISO Isoproterenol results in increased expression of MAN1A mRNA CTD PMID:20003209 NCBI chr20:35,257,688...35,450,132
Ensembl chr20:35,257,985...35,450,513
JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 increases expression ISO Isoproterenol results in increased expression of MAN2A1 mRNA CTD PMID:20003209 NCBI chr 9:112,293,388...112,451,677
Ensembl chr 9:112,293,388...112,451,677
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP
ISO
MAP2K1 protein affects the reaction [Isoproterenol results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; MAP2K1 protein promotes the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:10888249, PMID:21177286 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Isoproterenol results in decreased expression of MAP3K5 mRNA CTD PMID:21335049 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K6 mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr 5:151,435,679...151,448,329
Ensembl chr 5:151,436,464...151,448,328
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MAP3K8 mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Map7 microtubule-associated protein 7 increases expression ISO Isoproterenol results in increased expression of MAP7 mRNA CTD PMID:20003209 NCBI chr 1:15,620,665...15,748,203
Ensembl chr 1:15,620,653...15,748,203
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
increases phosphorylation
multiple interactions
ISO
EXP
Isoproterenol results in increased activity of MAPK1 protein
Isoproterenol results in increased phosphorylation of MAPK1 protein
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK1 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]
[Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK1 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein]
CTD PMID:10888249, PMID:11093795, PMID:15292328, PMID:16980553, PMID:17623046, PMID:17925438, PMID:19002953, PMID:19483313, PMID:21177286, PMID:26692091 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein] CTD PMID:18089841 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
[Isoproterenol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [Isoproterenol binds to and results in increased activity of ADRB2 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein; ARRB2 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Isoproterenol inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein]
DUSP1 protein inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; MAP2K1 protein promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
Isoproterenol inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAP2K1 protein affects the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MIR214 mRNA promotes the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]; Propranolol inhibits the reaction [Isoproterenol results in increased activity of MAPK3 protein]; SL 327 inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:10888249, PMID:11093795, PMID:15292328, PMID:16980553, PMID:17623046, PMID:17925438, PMID:19002953, PMID:19483313, PMID:20215810, PMID:21177286, PMID:26692091 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]
Isoproterenol results in increased activity of MAPK8 protein
2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein]
CTD PMID:10591028, PMID:15951400, PMID:20562518 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 increases expression ISO Isoproterenol results in increased expression of MARCHF7 mRNA CTD PMID:20003209 NCBI chr 3:46,284,961...46,325,230
Ensembl chr 3:46,286,712...46,324,057
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Isoproterenol results in decreased expression of MAS1 protein CTD PMID:20409916 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Mb myoglobin increases expression
multiple interactions
increases secretion
EXP Isoproterenol results in increased expression of MB protein
sinapinic acid inhibits the reaction [Isoproterenol results in increased expression of MB protein]
Isoproterenol results in increased secretion of MB protein
CTD PMID:533011, PMID:19628585, PMID:32627257 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 increases expression ISO Isoproterenol results in increased expression of MBD1 mRNA CTD PMID:20003209 NCBI chr18:70,248,568...70,263,190
Ensembl chr18:70,248,713...70,263,164
JBrowse link
G Mbd5 methyl-CpG binding domain protein 5 increases expression ISO Isoproterenol results in increased expression of MBD5 mRNA CTD PMID:20003209 NCBI chr 3:33,364,812...33,504,144
Ensembl chr 3:33,440,191...33,504,238
JBrowse link
G Mccc2 methylcrotonoyl-CoA carboxylase 2 decreases expression ISO Isoproterenol results in decreased expression of MCCC2 mRNA CTD PMID:20003209 NCBI chr 2:30,175,017...30,246,028
Ensembl chr 2:30,175,018...30,246,010
JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like increases expression ISO Isoproterenol results in increased expression of MCF2L mRNA CTD PMID:20003209 NCBI chr16:81,839,686...81,986,007
Ensembl chr16:81,839,653...81,980,027
JBrowse link
G Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 decreases expression ISO Isoproterenol results in decreased expression of MDGA1 mRNA CTD PMID:20003209 NCBI chr20:8,515,142...8,574,632
Ensembl chr20:8,515,142...8,574,082
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO Isoproterenol results in decreased expression of MEF2C mRNA CTD PMID:20003209 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Meig1 meiosis/spermiogenesis associated 1 decreases expression ISO Isoproterenol results in decreased expression of MEIG1 mRNA CTD PMID:20003209 NCBI chr17:78,813,656...78,829,411
Ensembl chr17:78,817,529...78,829,411
JBrowse link
G Metrn meteorin, glial cell differentiation regulator decreases expression ISO Isoproterenol results in decreased expression of METRN mRNA CTD PMID:20003209 NCBI chr10:15,164,439...15,166,457
Ensembl chr10:15,164,439...15,166,457
JBrowse link
G Mfap5 microfibril associated protein 5 increases expression ISO Isoproterenol results in increased expression of MFAP5 mRNA CTD PMID:20003209 NCBI chr 4:155,313,671...155,336,228
Ensembl chr 4:155,313,671...155,336,228
JBrowse link
G Mfn1 mitofusin 1 decreases expression EXP Isoproterenol results in decreased expression of MFN1 protein CTD PMID:27491814 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mfn2 mitofusin 2 decreases expression EXP Isoproterenol results in decreased expression of MFN2 protein CTD PMID:26692091, PMID:27491814 NCBI chr 5:164,684,244...164,715,414
Ensembl chr 5:164,684,509...164,714,145
JBrowse link
G Mgll monoglyceride lipase decreases expression ISO Isoproterenol results in decreased expression of MGLL mRNA CTD PMID:20003209 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mgp matrix Gla protein increases expression ISO Isoproterenol results in increased expression of MGP mRNA CTD PMID:20003209 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Isoproterenol results in increased expression of MGST1 mRNA CTD PMID:20003209, PMID:21335049 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mib1 mindbomb E3 ubiquitin protein ligase 1 increases expression ISO Isoproterenol results in increased expression of MIB1 mRNA CTD PMID:20003209 NCBI chr18:1,970,914...2,094,920
Ensembl chr18:1,970,914...2,094,920
JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression ISO Isoproterenol results in decreased expression of MIR133A1 CTD PMID:19893015 NCBI chr18:2,052,478...2,052,564 JBrowse link
G Mir142 microRNA 142 increases expression EXP Isoproterenol results in increased expression of MIR142 mRNA CTD PMID:29355689 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir155 microRNA 155 increases expression EXP Isoproterenol results in increased expression of MIR155 mRNA CTD PMID:29355689 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir19a microRNA 19a increases expression EXP Isoproterenol results in increased expression of MIR19A mRNA CTD PMID:29355689 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir208a microRNA 208a increases expression
decreases expression
EXP Isoproterenol results in increased expression of MIR208A
Isoproterenol results in decreased expression of MIR208A mRNA
CTD PMID:26454886, PMID:29355689 NCBI chr15:33,613,451...33,613,533 JBrowse link
G Mir208b microRNA 208b increases expression EXP Isoproterenol results in increased expression of MIR208B mRNA CTD PMID:29355689 NCBI chr15:33,639,510...33,639,621
Ensembl chr15:33,639,510...33,639,621
JBrowse link
G Mir21 microRNA 21 increases expression EXP Isoproterenol results in increased expression of MIR21 mRNA CTD PMID:28526319, PMID:29355689 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression ISO Isoproterenol results in increased expression of MKNK2 mRNA CTD PMID:20003209 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Mlf1 myeloid leukemia factor 1 decreases expression ISO Isoproterenol results in decreased expression of MLF1 mRNA CTD PMID:20003209 NCBI chr 2:164,549,423...164,582,645
Ensembl chr 2:164,549,455...164,582,643
JBrowse link
G Mlh1 mutL homolog 1 increases expression ISO Isoproterenol results in increased expression of MLH1 mRNA CTD PMID:21335049 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mmd monocyte to macrophage differentiation-associated decreases expression ISO Isoproterenol results in decreased expression of MMD mRNA CTD PMID:20003209 NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression
multiple interactions
EXP Isoproterenol results in increased expression of MMP1
SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP1]
CTD PMID:12883319 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp11 matrix metallopeptidase 11 increases expression ISO Isoproterenol results in increased expression of MMP11 mRNA CTD PMID:20003209 NCBI chr20:13,670,051...13,678,834
Ensembl chr20:13,670,066...13,678,089
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Isoproterenol results in increased expression of MMP14 mRNA CTD PMID:21335049 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Mmp15 matrix metallopeptidase 15 decreases expression ISO Isoproterenol results in decreased expression of MMP15 mRNA CTD PMID:20003209 NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
increases activity
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in increased activity of MMP2]
Isoproterenol results in increased expression of MMP2 mRNA
Isoproterenol results in increased expression of MMP2 protein
CTD PMID:16327176, PMID:18089841, PMID:24929186 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO
EXP
Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MMP3 mRNA]
SI 27 inhibits the reaction [Isoproterenol results in increased expression of MMP3]
CTD PMID:12883319, PMID:18089841, PMID:20003209 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases activity
ISO
EXP
Propranolol inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]
CPU0213 inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]; pimagedine inhibits the reaction [Isoproterenol results in increased expression of MMP9 mRNA]
Isoproterenol results in increased activity of MMP9
Doxycycline inhibits the reaction [Isoproterenol results in increased activity of MMP9]
CTD PMID:16574429, PMID:18089841, PMID:18594475, PMID:24929186 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mmrn1 multimerin 1 increases expression ISO Isoproterenol results in increased expression of MMRN1 mRNA CTD PMID:20003209 NCBI chr 4:90,977,537...91,038,747
Ensembl chr 4:90,990,088...91,038,748
JBrowse link
G Mospd2 motile sperm domain containing 2 increases expression ISO Isoproterenol results in increased expression of MOSPD2 mRNA CTD PMID:20003209 NCBI chr  X:31,140,967...31,182,823
Ensembl chr  X:31,140,960...31,182,816
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP caffeic acid phenethyl ester inhibits the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:20693123 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpp7 membrane palmitoylated protein 7 increases expression ISO Isoproterenol results in increased expression of MPP7 mRNA CTD PMID:20003209 NCBI chr17:60,057,077...60,250,303
Ensembl chr17:60,059,949...60,250,352
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Isoproterenol results in increased expression of MRC1 mRNA CTD PMID:20003209 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 decreases expression ISO Isoproterenol results in decreased expression of MRPL41 mRNA CTD PMID:20003209 NCBI chr 3:2,181,044...2,181,962
Ensembl chr 3:2,181,045...2,181,962
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 decreases expression ISO Isoproterenol results in decreased expression of MRPL45 mRNA CTD PMID:20003209 NCBI chr10:85,257,876...85,269,806
Ensembl chr10:85,257,876...85,269,806
JBrowse link
G Msr1 macrophage scavenger receptor 1 increases expression ISO Isoproterenol results in increased expression of MSR1 mRNA CTD PMID:20003209 NCBI chr16:56,817,714...56,900,025
Ensembl chr16:56,813,791...56,900,052
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209, PMID:21335049 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
ISO Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MT2 mRNA] CTD PMID:18089841, PMID:20003209 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtch2 mitochondrial carrier 2 increases expression ISO Isoproterenol results in increased expression of MTCH2 mRNA CTD PMID:20003209 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation
multiple interactions
EXP Isoproterenol results in increased phosphorylation of MTOR protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]; Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased phosphorylation of MTOR protein]]
CTD PMID:17623046, PMID:25045214 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression ISO Isoproterenol results in decreased expression of MTSS1 mRNA CTD PMID:20003209 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 increases expression ISO Isoproterenol results in increased expression of MUSTN1 mRNA CTD PMID:20003209 NCBI chr16:6,962,737...6,964,987
Ensembl chr16:6,962,722...6,964,989
JBrowse link
G Mybpc3 myosin binding protein C3 multiple interactions
affects response to substance
ISO MYBPC3 gene mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]
MYBPC3 protein affects the susceptibility to Isoproterenol
MYBPC3 mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]
CTD PMID:22076249, PMID:23896226 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP
ISO
Isoproterenol results in increased expression of MYC mRNA CTD PMID:20003209, PMID:20211217, PMID:21823215 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Isoproterenol results in decreased expression of MYCN mRNA CTD PMID:20003209 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression
multiple interactions
EXP Isoproterenol results in increased expression of MYD88 mRNA
Metformin inhibits the reaction [Isoproterenol results in increased expression of MYD88 mRNA]
CTD PMID:24842192 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Myh6 myosin heavy chain 6 increases expression
multiple interactions
ISO Isoproterenol results in increased expression of MYH6 protein
plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH6 protein]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of MYH6 protein]
CTD PMID:31009642 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
increases expression
ISO
EXP
[Phenylephrine co-treated with Isoproterenol] results in increased expression of MYH7 mRNA; Doxycycline inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; Valsartan inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]
Isoproterenol results in increased expression of MYH7 mRNA; Isoproterenol results in increased expression of MYH7 protein
G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; G3BP2 protein promotes the reaction [Isoproterenol results in increased expression of MYH7 protein]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; plantamajoside inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein]; RELA mRNA promotes the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]]
CTD PMID:10710348, PMID:18089841, PMID:18851973, PMID:25045214, PMID:28816235, PMID:31009642 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myh7b myosin heavy chain 7B decreases expression ISO Isoproterenol results in decreased expression of MYH7B mRNA CTD PMID:20003209 NCBI chr 3:151,105,038...151,150,621
Ensembl chr 3:151,126,591...151,150,344
JBrowse link
G Myl1 myosin, light chain 1 increases expression EXP Isoproterenol results in increased expression of MYL1 protein CTD PMID:19854236 NCBI chr 9:73,937,820...73,958,480
Ensembl chr 9:73,937,823...73,958,480
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G Myl3 myosin light chain 3 increases expression EXP Isoproterenol results in increased expression of MYL3 protein CTD PMID:24286936 NCBI chr 8:119,030,852...119,036,996
Ensembl chr 8:119,030,875...119,036,996
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G Mylip myosin regulatory light chain interacting protein increases expression ISO Isoproterenol results in increased expression of MYLIP mRNA CTD PMID:20003209 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
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G Myo5a myosin VA increases expression ISO Isoproterenol results in increased expression of MYO5A mRNA CTD PMID:20003209 NCBI chr 8:82,038,966...82,156,507
Ensembl chr 8:82,037,977...82,156,617
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G Myot myotilin increases expression ISO Isoproterenol results in increased expression of MYOT mRNA CTD PMID:20003209 NCBI chr18:35,573,978...35,593,541
Ensembl chr18:35,574,002...35,593,541
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G Myrip myosin VIIA and Rab interacting protein increases expression ISO Isoproterenol results in increased expression of MYRIP mRNA CTD PMID:20003209 NCBI chr 8:128,972,307...129,139,257
Ensembl chr 8:128,972,311...129,139,251
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G N4bp2l1 NEDD4 binding protein 2-like 1 increases expression ISO Isoproterenol results in increased expression of N4BP2L1 mRNA CTD PMID:20003209 NCBI chr12:546,759...576,744
Ensembl chr12:546,760...576,746
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G Nab1 Ngfi-A binding protein 1 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB1 mRNA CTD PMID:10710348 NCBI chr 9:53,906,073...53,945,474
Ensembl chr 9:53,906,073...53,945,473
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G Nab2 Ngfi-A binding protein 2 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA] CTD PMID:10710348 NCBI chr 7:70,963,580...70,971,471
Ensembl chr 7:70,961,575...70,969,905
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G Nabp1 nucleic acid binding protein 1 decreases expression ISO Isoproterenol results in decreased expression of NABP1 mRNA CTD