CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2,4-diaminobutyric acid
Accession: CHEBI:64307
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Definition: A diamino acid that is butyric acid in which a hydrogen at position 2 and a hydrogen at position 4 are replaced by amino groups.
Synonyms: related_synonym: 2,4-diaminobutanoic acid; Dbu; Formula=C4H10N2O2; InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8); InChIKey=OGNSCSPNOLGXSM-UHFFFAOYSA-N; SMILES=NCCC(N)C(O)=O; alpha,gamma-diaminobutanoic acid; alpha,gamma-diaminobutyric acid
xref: CAS:305-62-4
xref_mesh: MESH:C005959
xref: Reaxys:1721676
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Casp3
caspase 3
multiple interactions
ISO
[beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CASP3 protein
CTD
PMID:28634653
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cox6b1
cytochrome c oxidase subunit 6B1
multiple interactions
ISO
[beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of COX6B1 mRNA
CTD
PMID:28634653
NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001 Ensembl chr 2:85,875,109...85,884,001
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Ctsb
cathepsin B
multiple interactions
ISO
[beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CTSB protein
CTD
PMID:28634653
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Ctsl
cathepsin L
multiple interactions
ISO
[beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CTSL protein
CTD
PMID:28634653
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Gpt2
glutamic--pyruvic transaminase 2
multiple interactions
ISO
[beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of GPT2 mRNA
CTD
PMID:28634653
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
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