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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4-diaminobutyric acid
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Accession:CHEBI:64307 term browser browse the term
Definition:A diamino acid that is butyric acid in which a hydrogen at position 2 and a hydrogen at position 4 are replaced by amino groups.
Synonyms:related_synonym: 2,4-diaminobutanoic acid;   Dbu;   Formula=C4H10N2O2;   InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8);   InChIKey=OGNSCSPNOLGXSM-UHFFFAOYSA-N;   SMILES=NCCC(N)C(O)=O;   alpha,gamma-diaminobutanoic acid;   alpha,gamma-diaminobutyric acid
 xref: CAS:305-62-4
 xref_mesh: MESH:C005959
 xref: Reaxys:1721676



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2,4-diaminobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CASP3 protein CTD PMID:28634653 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of COX6B1 mRNA CTD PMID:28634653 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
JBrowse link
G Ctsb cathepsin B multiple interactions ISO [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CTSB protein CTD PMID:28634653 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased activity of CTSL protein CTD PMID:28634653 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 multiple interactions ISO [beta-N-methylamino-L-alanine co-treated with 2,4-diaminobutyric acid] results in increased expression of GPT2 mRNA CTD PMID:28634653 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        refrigerant 17688
          ammonia 17277
            organic amino compound 17277
              amino acid 14872
                diamino acid 32
                  2,4-diaminobutyric acid 5
                    D-2,4-diaminobutyric acid 0
                    L-2,4-diaminobutyric acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        monocarboxylic acid 17622
                                          fatty acid 16011
                                            short-chain fatty acid 15700
                                              fatty acid 4:0 7905
                                                butyric acid 6275
                                                  2,4-diaminobutyric acid 5
                                                    D-2,4-diaminobutyric acid 0
                                                    L-2,4-diaminobutyric acid + 0
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