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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glutaraldehyde
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Accession:CHEBI:64276 term browser browse the term
Definition:A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Synonyms:related_synonym: 1,3-Diformylpropane;   1,5-Pentanedial;   1,5-Pentanedione;   Formula=C5H8O2;   Glutardialdehyde;   Glutaric acid dialdehyde;   Glutaric dialdehyde;   InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2;   InChIKey=SXRSQZLOMIGNAQ-UHFFFAOYSA-N;   PENTANEDIAL;   SMILES=O=CCCCC=O;   glutaral;   glutaralum
 alt_id: CHEBI:45072
 xref: Beilstein:605390;   CAS:111-30-8;   Drug_Central:3267;   HMDB:HMDB0029599;   KEGG:C12518;   KEGG:D01120
 xref_mesh: MESH:D005976
 xref: PDBeChem:PTD;   PMID:10672649;   PMID:11378863;   PMID:22020189;   PMID:22221459;   PMID:22233542;   PMID:22266295;   PMID:22269730;   PMID:22348538;   PMID:22351440;   PMID:24332617;   PMID:7701454;   PMID:9582689;   PPDB:1567;   Reaxys:605390;   Wikipedia:Glutaraldehyde


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glutaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO Glutaral results in increased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Casp8 caspase 8 decreases expression ISO Glutaral results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Glutaral results in increased expression of CCL4 mRNA CTD PMID:20713136 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Cd86 CD86 molecule increases expression ISO Glutaral results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Glutaral results in decreased activity of G6PD protein CTD PMID:19490936 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Glutaral results in decreased expression of GJA1 protein CTD PMID:19932693 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions		 ISO Glutaral results in decreased activity of GSR protein
Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]		 CTD PMID:19490936 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Glutaral results in increased expression of IL1R2 mRNA CTD PMID:20713136 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il6 interleukin 6 affects expression ISO Glutaral affects the expression of IL6 mRNA CTD PMID:20200221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression
increases expression		 ISO Glutaral results in decreased expression of MUC1 protein
Glutaral results in increased expression of MUC1 protein		 CTD PMID:38360295 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Glutaral results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Tnf tumor necrosis factor affects expression
increases expression		 ISO Glutaral affects the expression of TNF mRNA
Glutaral results in increased expression of TNF mRNA		 CTD PMID:20200221 PMID:28236482 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Glutaral results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        fixative 48
          glutaraldehyde 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            heteroorganic entity 19556
                              organochalcogen compound 19315
                                organooxygen compound 19205
                                  carbon oxoacid 18694
                                    carboxylic acid 18691
                                      carboacyl group 17723
                                        univalent carboacyl group 17723
                                          formyl group 9008
                                            aldehyde 9008
                                              dialdehyde 141
                                                glutaraldehyde 13
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