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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glutaraldehyde
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Accession:CHEBI:64276 term browser browse the term
Definition:A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Synonyms:related_synonym: 1,3-Diformylpropane;   1,5-Pentanedial;   1,5-Pentanedione;   Formula=C5H8O2;   Glutardialdehyde;   Glutaric acid dialdehyde;   Glutaric dialdehyde;   InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2;   InChIKey=SXRSQZLOMIGNAQ-UHFFFAOYSA-N;   PENTANEDIAL;   SMILES=O=CCCCC=O;   glutaral;   glutaralum
 alt_id: CHEBI:45072
 xref: Beilstein:605390;   CAS:111-30-8;   Drug_Central:3267;   HMDB:HMDB0029599;   KEGG:C12518;   KEGG:D01120
 xref_mesh: MESH:D005976
 xref: PDBeChem:PTD;   PMID:10672649;   PMID:11378863;   PMID:22020189;   PMID:22221459;   PMID:22233542;   PMID:22266295;   PMID:22269730;   PMID:22348538;   PMID:22351440;   PMID:24332617;   PMID:7701454;   PMID:9582689;   PPDB:1567;   Reaxys:605390;   Wikipedia:Glutaraldehyde



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glutaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO Glutaral results in increased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Casp8 caspase 8 decreases expression ISO Glutaral results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Glutaral results in increased expression of CCL4 mRNA CTD PMID:20713136 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Cd86 CD86 molecule increases expression ISO Glutaral results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Glutaral results in decreased activity of G6PD protein CTD PMID:19490936 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Glutaral results in decreased expression of GJA1 protein CTD PMID:19932693 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO Glutaral results in decreased activity of GSR protein
Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]
CTD PMID:19490936 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Glutaral results in increased expression of IL1R2 mRNA CTD PMID:20713136 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il6 interleukin 6 affects expression ISO Glutaral affects the expression of IL6 mRNA CTD PMID:20200221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Glutaral results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Tnf tumor necrosis factor affects expression
increases expression
ISO Glutaral affects the expression of TNF mRNA
Glutaral results in increased expression of TNF mRNA
CTD PMID:20200221 PMID:28236482 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Glutaral results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        fixative 42
          glutaraldehyde 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        carboacyl group 17730
                                          univalent carboacyl group 17710
                                            formyl group 8806
                                              aldehyde 8806
                                                dialdehyde 130
                                                  glutaraldehyde 12
paths to the root