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Accession:CHEBI:64164 term browser browse the term
Definition:An aminoquinoline that consists of quinoline in which the hydrogen at position 2 is substituted by a 4-methylpiperazin-1-yl group. A 5-HT3 agonist. Has almost the same affinity for 5-HT3 sites as quipazine but unlike the latter, does not bind to 5-HT1B sites.
Synonyms:related_synonym: Formula=C14H17N3;   InChI=1S/C14H17N3/c1-16-8-10-17(11-9-16)14-7-6-12-4-2-3-5-13(12)15-14/h2-7H,8-11H2,1H3;   InChIKey=HOMWNUXPSJQSSU-UHFFFAOYSA-N;   SMILES=CN1CCN(CC1)c1ccc2ccccc2n1
 xref: LINCS:LSM-3379
 xref_mesh: MESH:C109625
 xref: PMID:10638822 "Europe PMC";   PMID:15848758 "Europe PMC";   PMID:2583244 "Europe PMC";   PMID:9290075 "Europe PMC";   PMID:9622544 "Europe PMC";   Reaxys:887071 "Reaxys"

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N-methylquipazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Taar1 trace-amine-associated receptor 1 JBrowse link 1 22,595,477 22,596,475 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          neurotransmitter agent 16233
            serotonergic drug 3846
              serotonergic agonist 878
                N-methylquipazine 1
                  N-methylquipazine dimaleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        aromatic amine 13572
                                          aminoquinoline 1547
                                            N-methylquipazine 1
                                              N-methylquipazine dimaleate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.