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Accession:CHEBI:64156 term browser browse the term
Definition:An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.
Synonyms:exact_synonym: 2-(1H-imidazol-4-yl)ethyl carbamimidothioate
 related_synonym: Formula=C6H10N4S;   InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10);   InChIKey=PEHSVUKQDJULKE-UHFFFAOYSA-N;   S-(2-(4-Imidazolyl)ethyl)isothiourea;   SMILES=NC(=N)SCCc1c[nH]cn1
 xref: CAS:102203-18-9;   KEGG:C17931
 xref_mesh: MESH:C077430
 xref: Reaxys:880781;   Wikipedia:Imetit
 cyclic_relationship: is_conjugate_base_of CHEBI:64157

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imetit term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrh3 histamine receptor H3 JBrowse link 3 175,474,310 175,479,395 RGD:6480464
G Hrh4 histamine receptor H4 JBrowse link 18 4,365,429 4,382,599 RGD:6480464
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:6480464

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19779
    chemical entity 19778
      atom 19777
        nonmetal atom 19651
          sulfur atom 16274
            sulfur molecular entity 16274
              organosulfur compound 15203
                imidothiocarbamic ester 70
                  imetit 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic molecule 19472
                              organic cyclic compound 19236
                                organic heterocyclic compound 18361
                                  heteroarene 15898
                                    monocyclic heteroarene 13313
                                      azole 12476
                                        diazole 8135
                                          imidazoles 7666
                                            imetit 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.