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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:NAN 190(1+)
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Accession:CHEBI:64132 term browser browse the term
Definition:An organic cation obtained by selective protonation at position 1 of the piperidine ring in NAN 190.
Synonyms:exact_synonym: 1-[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butyl]-4-(2-methoxyphenyl)piperazin-1-ium
 related_synonym: Formula=C23H28N3O3;   InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3/p+1;   InChIKey=SJDOMIRMMUGQQK-UHFFFAOYSA-O;   NAN 190 cation;   SMILES=COc1ccccc1N1CC[NH+](CCCCN2C(=O)c3ccccc3C2=O)CC1
 cyclic_relationship: is_conjugate_acid_of CHEBI:64131


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NAN 190 hydrobromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:15213358 PMID:15482641 PMID:16528294 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      molecular entity 19770
        ion 15945
          organic ion 8455
            organic cation 7309
              NAN 190(1+) 1
                NAN 190 hydrobromide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    main group molecular entity 19658
                      s-block molecular entity 19423
                        hydrogen molecular entity 19416
                          hydrides 18755
                            inorganic hydride 17460
                              pnictogen hydride 17435
                                nitrogen hydride 17281
                                  ammonium 8216
                                    ammonium ion derivative 8212
                                      NAN 190(1+) 1
                                        NAN 190 hydrobromide 1
paths to the root