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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:NAN 190(1+)
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Accession:CHEBI:64132 term browser browse the term
Definition:An organic cation obtained by selective protonation at position 1 of the piperidine ring in NAN 190.
Synonyms:exact_synonym: 1-[4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butyl]-4-(2-methoxyphenyl)piperazin-1-ium
 related_synonym: Formula=C23H28N3O3;   InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3/p+1;   InChIKey=SJDOMIRMMUGQQK-UHFFFAOYSA-O;   NAN 190 cation;   SMILES=COc1ccccc1N1CC[NH+](CCCCN2C(=O)c3ccccc3C2=O)CC1
 cyclic_relationship: is_conjugate_acid_of CHEBI:64131



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NAN 190 hydrobromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Serotonin
[1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine
CTD PMID:15213358 PMID:15482641 PMID:16528294 NCBI chr 2:36,694,174...36,695,442
Ensembl chr 2:36,694,174...36,695,442
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    chemical entity 20049
      molecular entity 20047
        ion 16332
          organic ion 9186
            organic cation 8124
              NAN 190(1+) 1
                NAN 190 hydrobromide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    main group molecular entity 19948
                      s-block molecular entity 19735
                        hydrogen molecular entity 19727
                          hydrides 19093
                            inorganic hydride 17893
                              pnictogen hydride 17876
                                nitrogen hydride 17767
                                  ammonium 8240
                                    ammonium ion derivative 8236
                                      NAN 190(1+) 1
                                        NAN 190 hydrobromide 1
paths to the root