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ONTOLOGY REPORT - ANNOTATIONS


Term:1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine
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Accession:CHEBI:64093 term browser browse the term
Definition:An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Synonyms:exact_synonym: 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine
 related_synonym: Formula=C28H34N2O;   GBR 12935;   GBR12935;   InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2;   InChIKey=RAQPOZGWANIDQT-UHFFFAOYSA-N;   SMILES=C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1
 xref: CAS:76778-22-8 "ChemIDplus";   LINCS:LSM-3101
 xref_mesh: MESH:C044630
 xref: PMID:1346964 "Europe PMC";   PMID:18596684 "Europe PMC";   PMID:18784647 "Europe PMC";   PMID:19924693 "Europe PMC";   PMID:20576034 "Europe PMC";   PMID:21693154 "Europe PMC";   PMID:21741457 "Europe PMC";   PMID:21990355 "Europe PMC";   PMID:2952763 "Europe PMC";   PMID:3436357 "Europe PMC";   PMID:8007761 "Europe PMC";   PMID:9286626 "Europe PMC";   Reaxys:578614 "Reaxys";   Wikipedia:GBR-12935
 cyclic_relationship: is_conjugate_base_of CHEBI:64092


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1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        refrigerant 16994
          ammonia 16561
            organic amino compound 16560
              tertiary amino compound 8521
                1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine 2
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Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          N-alkylpiperazine 2953
                                            1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine 2
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