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Accession:CHEBI:64045 term browser browse the term
Definition:A member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist. It is an atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects.
Synonyms:exact_synonym: 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
 related_synonym: 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide;   4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide;   Aminosultopride;   Formula=C17H27N3O4S;   InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21);   InChIKey=NTJOBXMMWNYJFB-UHFFFAOYSA-N;   SMILES=CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC;   amisulprida;   amisulpridum
 xref: CAS:71675-85-9;   DrugBank:DB06288;   Drug_Central:179;   HMDB:HMDB0015633;   KEGG:D07310;   LINCS:LSM-1669
 xref_mesh: MESH:D000077582
 xref: PMID:21176108;   PMID:21647545;   PMID:21663752;   PMID:21746752;   PMID:21822161;   PMID:21845006;   PMID:21852060;   PMID:21886905;   PMID:21888613;   PMID:21969105;   PMID:22035899;   PMID:22059694;   PMID:22121864;   PMID:22241281;   PMID:22250612;   Patent:BE872585;   Patent:US4401822;   Reaxys:6876191;   Wikipedia:Amisulpride

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amisulpride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Vipr2 vasoactive intestinal peptide receptor 2 JBrowse link 6 143,932,960 144,009,476 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        xenobiotic 18412
          amisulpride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18475
                              organic divalent group 18468
                                organodiyl group 18468
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic acid 18034
                                        carboacyl group 17190
                                          univalent carboacyl group 17190
                                            carbamoyl group 16928
                                              carboxamide 16928
                                                monocarboxylic acid amide 14575
                                                  arenecarboxamide 6513
                                                    benzamides 6513
                                                      amisulpride 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.