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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor
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Accession:CHEBI:64033 term browser browse the term
Definition:An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of fatty acid amide hydrolase (EC 3.5.1.99).
Synonyms:related_synonym: EC 3.5.1.99 inhibitor;   EC 3.5.1.99 inhibitors;   FAAH inhibitor;   FAAH inhibitors;   anandamide amidohydrolase inhibitor;   anandamide amidohydrolase inhibitors;   arachidonoylethanolamide amidohydrolase inhibitor;   arachidonoylethanolamide amidohydrolase inhibitors;   fatty acid amide hydrolase (EC 3.5.1.99) inhibitors;   fatty acid amide hydrolase inhibitor;   fatty acid amide hydrolase inhibitors;   fatty acylamide amidohydrolase inhibitor;   fatty acylamide amidohydrolase inhibitors;   oleamide hydrolase inhibitor;   oleamide hydrolase inhibitors
 xref: PMID:8083191



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biochanin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO biochanin A results in decreased activity of ABCC1 protein CTD PMID:15581599 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO biochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] CTD PMID:15955639 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO [[sodium arsenite results in increased abundance of Arsenic] which co-treated with biochanin A] results in increased activity of ACHE protein CTD PMID:33410021 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Agrn agrin decreases expression ISO biochanin A results in decreased expression of AGRN mRNA CTD PMID:12111696 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
affects binding
ISO
EXP
AHR protein affects the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; biochanin A promotes the reaction [AHR protein binds to CYP1A1 promoter]
biochanin A results in increased activity of AHR protein
biochanin A binds to AHR protein
CTD PMID:16903077 PMID:28985473 PMID:31621310 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases expression ISO biochanin A results in decreased expression of ALDH7A1 mRNA CTD PMID:12111696 NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193
JBrowse link
G Arid5b AT-rich interaction domain 5B increases expression ISO biochanin A results in increased expression of ARID5B mRNA CTD PMID:12111696 NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO biochanin A results in increased expression of BABAM2 mRNA CTD PMID:12111696 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO biochanin A results in decreased expression of BCL2 protein CTD PMID:12791511 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO biochanin A results in decreased expression of BCL2L1 protein CTD PMID:12791511 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 increases activity ISO biochanin A results in increased activity of CASP3 protein CTD PMID:12791511 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO biochanin A inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of CAT protein] CTD PMID:33410021 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO biochanin A results in decreased expression of CDH2 mRNA CTD PMID:12111696 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO biochanin A results in decreased expression of CDKN1A protein CTD PMID:12111696 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ckb creatine kinase B increases activity ISO biochanin A results in increased activity of CKB protein CTD PMID:16621514 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases expression
decreases activity
ISO [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein; [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA; biochanin A binds to and results in decreased activity of CYP19A1 protein
biochanin A results in decreased expression of CYP19A1 mRNA
biochanin A results in decreased activity of CYP19A1 protein
CTD PMID:9435150 PMID:16965912 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases hydroxylation
decreases methylation
increases expression
increases activity
ISO AHR protein affects the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; biochanin A promotes the reaction [AHR protein binds to CYP1A1 promoter]; Fulvestrant promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased hydroxylation of biochanin A
CYP1A1 protein results in decreased methylation of biochanin A
biochanin A results in increased activity of CYP1A1 protein
CTD PMID:15479032 PMID:16903077 PMID:28985473 PMID:31621310 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing
decreases activity
ISO
EXP
CYP1A2 protein results in increased metabolism of biochanin A
biochanin A results in decreased activity of CYP1A2 protein
CTD PMID:12814970 PMID:26278343 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases methylation
multiple interactions
increases expression
ISO CYP1B1 protein results in decreased methylation of biochanin A
Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]
AHR protein affects the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Butyric Acid promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; sodium propionate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]
CTD PMID:15479032 PMID:28985473 PMID:31621310 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 affects activity
increases activity
increases expression
affects expression
ISO biochanin A affects the activity of CYP27B1 protein
biochanin A analog results in increased activity of CYP27B1 protein; biochanin A results in increased activity of CYP27B1 protein
biochanin A analog results in increased expression of CYP27B1 mRNA; biochanin A results in increased expression of CYP27B1 mRNA
biochanin A affects the expression of CYP27B1 mRNA; biochanin A analog affects the expression of CYP27B1 mRNA
CTD PMID:15795327 PMID:17659868 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Dera deoxyribose-phosphate aldolase decreases expression ISO biochanin A results in decreased expression of DERA mRNA CTD PMID:12111696 NCBI chr 4:170,663,646...170,742,469
Ensembl chr 4:170,663,665...170,758,865
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO biochanin A results in decreased expression of EIF5 mRNA CTD PMID:12111696
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 decreases expression ISO biochanin A results in decreased expression of ENPP5 mRNA CTD PMID:12111696 NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 decreases expression ISO biochanin A results in decreased expression of EPS15 mRNA CTD PMID:12111696 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO biochanin A binds to and results in increased activity of ESR1 protein; biochanin A inhibits the reaction [Estradiol binds to ESR1 protein]
biochanin A binds to ESR1 protein
CTD PMID:9751507 PMID:12598185 PMID:14579009 PMID:16076101 PMID:19913605 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO
EXP
biochanin A binds to and results in increased activity of ESR2 protein; biochanin A inhibits the reaction [Estradiol binds to ESR2 protein]
biochanin A binds to ESR2 protein
CTD PMID:9751507 PMID:12224631 PMID:16076101 PMID:16566672 PMID:19913605 More... NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions
affects binding
ISO biochanin A binds to and results in increased activity of ESRRA protein; biochanin A promotes the reaction [ESRRA protein binds to PNRC1 protein]
biochanin A binds to ESRRA protein mutant form
CTD PMID:14638870 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Esrrb estrogen-related receptor beta multiple interactions ISO biochanin A binds to and results in increased activity of ESRRB protein; biochanin A promotes the reaction [ESRRB protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 6:106,007,662...106,163,136
Ensembl chr 6:106,008,095...106,160,791
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO biochanin A promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G Fbl fibrillarin increases expression ISO biochanin A results in increased expression of FBL mRNA CTD PMID:12111696 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
JBrowse link
G Folr1 folate receptor alpha decreases expression ISO biochanin A results in decreased expression of FOLR1 mRNA CTD PMID:12111696 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Gm2a GM2 ganglioside activator decreases expression ISO biochanin A results in decreased expression of GM2A mRNA CTD PMID:12111696 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression ISO biochanin A results in decreased expression of GNAI3 mRNA CTD PMID:12111696 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO biochanin A results in decreased expression of GPX1 mRNA CTD PMID:12111696 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased expression of ICAM1 protein] CTD PMID:22387535 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il17a interleukin 17A multiple interactions ISO biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il4 interleukin 4 increases expression ISO biochanin A results in increased expression of IL4 mRNA; biochanin A results in increased expression of IL4 protein CTD PMID:16169028 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased phosphorylation of LCK protein] CTD PMID:22387535 NCBI chr 5:141,888,319...141,916,992
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 decreases expression ISO biochanin A results in decreased expression of LDLRAD4 mRNA CTD PMID:12111696 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lxn latexin increases expression ISO biochanin A results in increased expression of LXN mRNA CTD PMID:12111696 NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression ISO biochanin A results in decreased expression of MMP14 protein CTD PMID:16598420 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO biochanin A results in decreased activity of MMP2 protein CTD PMID:16598420 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO biochanin A results in decreased activity of MMP9 protein CTD PMID:16598420 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mt2A metallothionein 2A increases expression ISO biochanin A results in increased expression of MT2A mRNA CTD PMID:10656621 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO biochanin A promotes the reaction [RORC protein binds to NCOA1 protein] CTD PMID:25583575 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 decreases expression ISO biochanin A results in decreased expression of NDUFA5 mRNA CTD PMID:12111696 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[sodium arsenite results in increased abundance of Arsenic] which co-treated with biochanin A] results in increased expression of NFE2L2 mRNA CTD PMID:33410021 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; biochanin A inhibits the reaction [pervanadate results in increased phosphorylation of NFKBIA protein] CTD PMID:22387535 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nono non-POU domain containing, octamer-binding decreases expression ISO biochanin A results in decreased expression of NONO mRNA CTD PMID:12111696 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO biochanin A inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO biochanin A binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO biochanin A results in increased cleavage of PARP1 protein CTD PMID:12791511 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pfdn5 prefoldin subunit 5 decreases expression ISO biochanin A results in decreased expression of PFDN5 mRNA CTD PMID:12111696 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516
JBrowse link
G Pgr progesterone receptor affects binding
increases expression
multiple interactions
ISO biochanin A binds to PGR protein
biochanin A results in increased expression of PGR mRNA
biochanin A inhibits the reaction [Progesterone binds to PGR protein]
CTD PMID:14579009 PMID:16076101 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO biochanin A results in decreased expression of PLAUR protein CTD PMID:16598420 NCBI chr 1:80,053,441...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions ISO biochanin A promotes the reaction [ESRRA protein binds to PNRC1 protein]; biochanin A promotes the reaction [ESRRB protein binds to PNRC1 protein]; biochanin A promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO biochanin A binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased expression of PTGS2 protein] CTD PMID:22387535 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rabl6 RAB, member RAS oncogene family-like 6 decreases expression ISO biochanin A results in decreased expression of RABL6 mRNA CTD PMID:12111696 NCBI chr 3:8,402,666...8,428,588
Ensembl chr 3:8,402,672...8,428,611
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression ISO biochanin A results in decreased expression of RELA mRNA CTD PMID:12111696 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rif1 replication timing regulatory factor 1 decreases expression ISO biochanin A results in decreased expression of RIF1 mRNA CTD PMID:12111696 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Rorc RAR-related orphan receptor C multiple interactions ISO biochanin A promotes the reaction [RORC protein binds to NCOA1 protein] CTD PMID:25583575 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Rpusd3 RNA pseudouridine synthase D3 decreases expression ISO biochanin A results in decreased expression of RPUSD3 mRNA CTD PMID:12111696 NCBI chr 4:146,553,230...146,562,794
Ensembl chr 4:146,558,562...146,562,794
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 increases expression ISO biochanin A results in increased expression of SH3GL1 mRNA CTD PMID:12111696 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions EXP [biochanin A results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate CTD PMID:17108059 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc25a3 solute carrier family 25 member 3 decreases expression ISO biochanin A results in decreased expression of SLC25A3 mRNA CTD PMID:12111696 NCBI chr 7:25,611,937...25,619,401 JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases activity
multiple interactions
EXP biochanin A results in decreased activity of SLCO1B1 protein
[biochanin A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [biochanin A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate
CTD PMID:32259555 NCBI chr 4:174,877,045...174,950,857
Ensembl chr 4:174,876,593...174,950,873
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO biochanin A results in decreased expression of SRSF1 mRNA CTD PMID:12111696 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP biochanin A results in increased expression of SULT1A1 mRNA; biochanin A results in increased expression of SULT1A1 protein CTD PMID:20391625 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 increases expression EXP biochanin A results in increased expression of SULT1E1 mRNA; biochanin A results in increased expression of SULT1E1 protein CTD PMID:20391625 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP biochanin A results in increased expression of SULT2A1 mRNA; biochanin A results in increased expression of SULT2A1 protein CTD PMID:20391625 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Susd6 sushi domain containing 6 increases expression ISO biochanin A results in increased expression of SUSD6 mRNA CTD PMID:12111696 NCBI chr 6:100,437,826...100,531,621
Ensembl chr 6:100,437,642...100,531,606
JBrowse link
G Syk spleen associated tyrosine kinase multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased phosphorylation of SYK protein] CTD PMID:22387535 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO biochanin A binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP biochanin A inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] CTD PMID:16735947 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 decreases expression ISO biochanin A results in decreased expression of TNFRSF21 mRNA CTD PMID:12111696 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO biochanin A results in increased expression of TUBB mRNA CTD PMID:12111696 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tyr tyrosinase increases expression ISO biochanin A results in increased expression of TYR mRNA CTD PMID:21071833 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 decreases expression ISO biochanin A results in decreased expression of UBE2D2 mRNA CTD PMID:12111696 NCBI chr18:27,364,665...27,405,589
Ensembl chr18:27,364,303...27,406,181
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases expression
ISO UGT1A1 protein results in increased glucuronidation of biochanin A
biochanin A results in increased expression of UGT1A1 mRNA
CTD PMID:14557274 PMID:31621310 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of biochanin A CTD PMID:14557274 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of biochanin A CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
EXP biochanin A inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Fulvestrant inhibits the reaction [biochanin A results in decreased expression of VCAM1 protein] CTD PMID:16223672 PMID:16735947 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Wdr74 WD repeat domain 74 decreases expression ISO biochanin A results in decreased expression of WDR74 mRNA CTD PMID:12111696 NCBI chr 1:205,631,769...205,636,563
Ensembl chr 1:205,631,824...205,636,563
JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO biochanin A results in decreased expression of WWC2 mRNA CTD PMID:12111696 NCBI chr16:44,258,372...44,421,815
Ensembl chr16:44,258,372...44,421,812
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          enzyme inhibitor 18380
            EC 3.* (hydrolase) inhibitor 17925
              EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 17804
                EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor 17804
                  EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor 85
                    N-arachidonoylserotonin 0
                    N-benzylhexadecanamide 0
                    biochanin A + 85
                    linoleoyl ethanolamide 0
paths to the root