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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:19-HETE
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Accession:CHEBI:63998 term browser browse the term
Definition:A HETE that consists of arachidonic acid bearing a hydroxy substituent at position 19.
Synonyms:exact_synonym: (5Z,8Z,11Z,14Z)-19-hydroxy-5,8,11,14-icosatetraenoic acid
 related_synonym: (5Z,8Z,11Z,14Z)-19-hydroxy-5,8,11,14-eicosatetraenoic acid;   (all-cis)-19-hydroxy-5,8,11,14-eicosatetraenoic acid;   (all-cis)-19-hydroxy-5,8,11,14-icosatetraenoic acid;   19-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid;   19-hydroxy-5Z,8Z,11Z,14Z-icosatetraenoic acid;   19-hydroxyarachidonic acid;   Formula=C20H32O3;   InChI=1S/C20H32O3/c1-19(21)17-15-13-11-9-7-5-3-2-4-6-8-10-12-14-16-18-20(22)23/h3-6,9-12,19,21H,2,7-8,13-18H2,1H3,(H,22,23)/b5-3-,6-4-,11-9-,12-10-;   InChIKey=XFUXZHQUWPFWPR-TWVHMNNTSA-N;   SMILES=CC(O)CCC\\C=C/C\\C=C/C\\C=C/C\\C=C/CCCC(O)=O
 xref: CAS:79551-85-2
 xref_mesh: MESH:C055986
 xref: Reaxys:3059697
 cyclic_relationship: is_conjugate_acid_of CHEBI:76627


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19-HETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing EXP CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15205388 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases chemical synthesis ISO CYP4F3 protein alternative form results in increased chemical synthesis of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:30259074 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    chemical entity 19761
      atom 19759
        nonmetal atom 19641
          carbon atom 19559
            organic molecular entity 19559
              fatty acid derivative 1042
                icosanoid 456
                  HETE 34
                    19-HETE 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        monocarboxylic acid 17523
                                          fatty acid 16011
                                            unsaturated fatty acid 949
                                              polyunsaturated fatty acid 685
                                                fatty acid 20:4 331
                                                  icosatetraenoic acid 331
                                                    icosa-5,8,11,14-tetraenoic acid 284
                                                      arachidonic acid 284
                                                        19-HETE 2
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