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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:13,14-dihydro-15-keto-PGF2alpha
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Accession:CHEBI:63976 term browser browse the term
Definition:A prostaglandin Fα obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin F2α.
Synonyms:related_synonym: (5Z,9alpha,11alpha)-9,11-dihydroxy-15-oxoprost-5-en-1-oic acid;   13,14-Dihydro-15-ketoprostaglandin F2alpha;   13,14-dihydro-15-keto-Prostaglandin F2a;   15-Keto-13,14-dihydroprostaglandin F2-alpha;   15-Keto-13,14-dihydroprostaglandin F2alpha;   9S,11S-dihydroxy-15-oxo-5Z-prostenoic acid;   PGFM;   dhk-PGF2alpha
 xref: CAS:27376-76-7;   HMDB:HMDB0004685
 xref_mesh: MESH:C008228
 xref: Patent:US5397797;   Reaxys:6227023;   lipidmaps:LMFA03010027;   pubmed:20961606;   pubmed:21228218;   pubmed:21615801;   pubmed:21653895;   pubmed:21741578;   pubmed:21924479;   pubmed:21940119;   pubmed:22192399
 chemrof_formula: C20H34O5
 chemrof_smiles: CCCCCC(=O)CC[C@@H]1[C@@H](C/C=CCCCC(=O)O)[C@@H](O)C[C@H]1O
 chemrof_inchi: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,16-19,22-23H,2-3,5-6,8-14H2,1H3,(H,24,25)/b7-4-/t16-,17-,18+,19-/m1/s1
 chemrof_inchikey: VKTIONYPMSCHQI-XAGFEHLVSA-N
 cyclic_relationship: has_functional_parent CHEBI:15553;   is_conjugate_acid_of CHEBI:133374


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13,14-dihydro-15-keto-PGF2alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgr1 prostaglandin reductase 1 increases abundance
multiple interactions 		ISO PTGR1 protein results in increased abundance of 15-keto-13,14-dihydroprostaglandin F2alpha
[PTGR1 protein results in increased metabolism of 15-ketoprostaglandin F2alpha] which results in increased abundance of 15-keto-13,14-dihydroprostaglandin F2alpha 		CTD PMID:25619643 NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        biochemical role 19888
          metabolite 19624
            13,14-dihydro-15-keto-PGF2alpha 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            lipid 17852
                              fatty acid derivative 4248
                                icosanoid 471
                                  prostanoid 406
                                    prostaglandin 398
                                      prostaglandins F 100
                                        prostaglandins Falpha 99
                                          13,14-dihydro-15-keto-PGF2alpha 1
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