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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cellulose synthesis inhibitor
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Accession:CHEBI:63958 term browser browse the term
Definition:An pathway inhibitor that inhibits the synthesis of cellulose.
Synonyms:related_synonym: cellulose biosynthesis inhibitor;   cellulose biosynthesis inhibitors;   cellulose synthesis inhibitors


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2,6-dichlorobenzonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases metabolic processing ISO CYP2A5 protein results in increased metabolism of dichlobanil CTD PMID:20840855 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Dexamethasone inhibits the reaction [dichlobanil results in increased expression of IL6 protein] CTD PMID:23921153 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Por cytochrome p450 oxidoreductase decreases response to substance ISO POR protein results in decreased susceptibility to dichlobanil CTD PMID:20840855 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
isoxaben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO isoxaben results in increased activity of NR1I2 protein CTD PMID:20143881 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          enzyme inhibitor 18150
            pathway inhibitor 8732
              cellulose synthesis inhibitor 4
                2,6-dichlorobenzonitrile 3
                N-[(1R,2S)-2,6-dimethyindan-1-yl]-6-[(1R)-1-fluoroethyl]-1,3,5-triazine-2,4-diamine + 0
                N-[(1R,2S)-2,6-dimethyindan-1-yl]-6-[(1S)-1-fluoroethyl]-1,3,5-triazine-2,4-diamine + 0
                ancymidol 0
                indaziflam 0
                isoxaben 1
                triaziflam 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.