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ONTOLOGY REPORT - ANNOTATIONS


Term:lansoprazole
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Accession:CHEBI:6375 term browser browse the term
Definition:A sulfoxide that has formula C16H14F3N3O2S.
Synonyms:exact_synonym: 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
 related_synonym: AG 1749;   Bamalite;   Formula=C16H14F3N3O2S;   InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22);   InChIKey=MJIHNNLFOKEZEW-UHFFFAOYSA-N;   Lanzol;   Lanzopral;   Lanzul;   Limpidex;   Monolitum;   Ogastro;   Opiren;   Prevacid;   SMILES=Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1;   lansoprazol;   lansoprazolum
 xref: Beilstein:4333393 "Beilstein";   CAS:103577-45-3 "ChemIDplus";   DrugBank:DB00448;   Drug_Central:1547 "DrugCentral";   KEGG:D00355;   LINCS:LSM-5064
 xref_mesh: MESH:D064747
 xref: Patent:EP174726;   Patent:US4628098;   Wikipedia:Lansoprazole


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lansoprazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA1 ATP binding cassette subfamily A member 1 JBrowse link 9 104,781,006 104,928,232 RGD:6480464
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:6480464
G AQP4 aquaporin 4 JBrowse link 18 26,852,038 26,865,803 RGD:6480464
G BAK1 BCL2 antagonist/killer 1 JBrowse link 6 33,572,552 33,580,296 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6480464
G C1QA complement C1q A chain JBrowse link 1 22,636,628 22,639,682 RGD:6480464
G C1QC complement C1q C chain JBrowse link 1 22,643,633 22,648,108 RGD:6480464
G C4BPA complement component 4 binding protein alpha JBrowse link 1 207,104,232 207,144,972 RGD:6480464
G C4BPB complement component 4 binding protein beta JBrowse link 1 207,088,795 207,099,993 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CFI complement factor I JBrowse link 4 109,730,982 109,802,225 RGD:6480464
G CGB3 chorionic gonadotropin subunit beta 3 JBrowse link 19 49,022,869 49,024,375 RGD:6480464
G CXCL1 C-X-C motif chemokine ligand 1 JBrowse link 4 73,869,393 73,871,308 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 JBrowse link 2 38,067,603 38,076,181 RGD:6480464
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 JBrowse link 10 94,683,729 94,736,190 RGD:6480464
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 JBrowse link 10 94,762,681 94,855,547 RGD:6480464
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 JBrowse link 10 95,036,772 95,069,497 RGD:6480464
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 JBrowse link 10 94,938,658 94,990,091 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 JBrowse link 7 99,648,194 99,679,996 RGD:6480464
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 JBrowse link 1 47,137,425 47,149,738 RGD:6480464
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:6480464
G FAS Fas cell surface death receptor JBrowse link 10 88,968,429 89,017,059 RGD:6480464
G FASLG Fas ligand JBrowse link 1 172,659,008 172,666,876 RGD:6480464
G FGF2 fibroblast growth factor 2 JBrowse link 4 122,826,708 122,898,236 RGD:6480464
G FGF21 fibroblast growth factor 21 JBrowse link 19 48,755,524 48,758,330 RGD:6480464
G GAST gastrin JBrowse link 17 41,712,331 41,715,969 RGD:6480464
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 67,583,812 67,586,653 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6480464
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G KEAP1 kelch like ECH associated protein 1 JBrowse link 19 10,486,125 10,503,356 RGD:6480464
G LHB luteinizing hormone subunit beta JBrowse link 19 49,015,980 49,017,091 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPT microtubule associated protein tau JBrowse link 17 45,894,382 46,028,334 RGD:6480464
G MPO myeloperoxidase JBrowse link 17 58,269,855 58,280,935 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G NR1H2 nuclear receptor subfamily 1 group H member 2 JBrowse link 19 50,376,457 50,383,388 RGD:6480464
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 JBrowse link 17 49,223,366 49,230,787 RGD:6480464
G POMC proopiomelanocortin JBrowse link 2 25,160,853 25,168,851 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RETSAT retinol saturase JBrowse link 2 85,341,955 85,354,528 RGD:6480464
G SERPING1 serpin family G member 1 JBrowse link 11 57,597,685 57,614,848 RGD:6480464
G SHH sonic hedgehog signaling molecule JBrowse link 7 155,799,980 155,812,463 RGD:6480464
G SLC22A2 solute carrier family 22 member 2 JBrowse link 6 160,216,755 160,258,821 RGD:6480464
G TGFA transforming growth factor alpha JBrowse link 2 70,447,284 70,553,826 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 2 233,760,270 233,773,300 RGD:6480464
G UGT2B17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 4 68,537,184 68,576,354 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 23758
    role 23647
      application 23047
        pharmaceutical 22602
          drug 22602
            anti-ulcer drug 753
              lansoprazole 66
Path 2
Term Annotations click to browse term
  CHEBI ontology 23758
    subatomic particle 23707
      composite particle 23707
        hadron 23707
          baryon 23707
            nucleon 23707
              atomic nucleus 23707
                atom 23707
                  main group element atom 23527
                    p-block element atom 23527
                      carbon group element atom 23238
                        carbon atom 23215
                          organic molecular entity 23215
                            organic molecule 23077
                              organic cyclic compound 22097
                                organic heterocyclic compound 20740
                                  organic heteropolycyclic compound 19863
                                    organic heterobicyclic compound 17269
                                      benzimidazoles 821
                                        lansoprazole 66
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.