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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:63687 term browser browse the term
Definition:An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (-)-(11S,2'R)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown.
Synonyms:exact_synonym: (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol
 related_synonym: (-)-Mefloquine;   Formula=C17H16F6N2O;   InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15+/m1/s1;   InChIKey=XEEQGYMUWCZPDN-DOMZBBRYSA-N;   SMILES=O[C@H]([C@H]1CCCCN1)c1cc(nc2c(cccc12)C(F)(F)F)C(F)(F)F;   [(11S,2'R)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol
 xref: CAS:51742-87-1;   LINCS:LSM-5525;   Reaxys:5629059
 cyclic_relationship: is_enantiomer_of CHEBI:63684

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  CHEBI ontology 242
    role 242
      biological role 242
        antimicrobial agent 109
          antimicrobial drug 34
            antiprotozoal drug 18
              antiplasmodial drug 2
                antimalarial 2
                  (-)-(11S,2'R)-erythro-mefloquine 0
                    mefloquine 0
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  CHEBI ontology 242
    subatomic particle 242
      composite particle 242
        hadron 242
          baryon 242
            nucleon 242
              atomic nucleus 242
                atom 242
                  main group element atom 235
                    p-block element atom 235
                      carbon group element atom 223
                        carbon atom 222
                          organic molecular entity 222
                            organic molecule 217
                              organic cyclic compound 201
                                organic heterocyclic compound 162
                                  organic heteromonocyclic compound 97
                                    piperidines 3
                                      [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol 0
                                        (-)-(11S,2'R)-erythro-mefloquine 0
                                          mefloquine 0
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