The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown.
Mefloquine inhibits the reaction [ABCC1 protein affects the export of fluorexon]; Mefloquine inhibits the reaction [ABCC1 protein affects the transport of S-(2,4-dinitrophenyl)glutathione]; Mefloquine inhibits the reaction [Prostaglandins E results in increased activity of ABCC1 protein]; Mefloquine inhibits the reaction [Quercetin results in increased activity of ABCC1 protein] Mefloquine results in decreased activity of ABCC1 protein
Mefloquine inhibits the reaction [ABCC4 protein affects the export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein]; Mefloquine inhibits the reaction [Prostaglandins E results in increased activity of ABCC4 protein]; Mefloquine inhibits the reaction [Quercetin results in increased activity of ABCC4 protein] Mefloquine results in decreased activity of ABCC4 protein
MTF1 protein affects the reaction [Mefloquine results in increased expression of HMOX1 mRNA]; MTF1 protein affects the reaction [Mefloquine results in increased expression of MT2A mRNA]