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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:63627 term browser browse the term
Definition:1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.
Synonyms:exact_synonym: 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
 related_synonym: Formula=C8H13N3O4S;   InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3;   InChIKey=HJLSLZFTEKNLFI-UHFFFAOYSA-N;   SMILES=CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O;   timidazole
 alt_id: CHEBI:32227
 xref: DrugBank:DB00911;   Drug_Central:2671;   KEGG:D01426;   LINCS:LSM-5948
 xref_mesh: MESH:D014011
 xref: PMID:5458368;   Patent:US3376311;   Reaxys:618182;   Wikipedia:Tinidazole

show annotations for term's descendants           Sort by:
tinidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Tinidazole results in decreased activity of ABCB11 protein
Tinidazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of Tinidazole CTD PMID:12920490 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      biological role 20000
        antimicrobial agent 17759
          antibacterial agent 14097
            antibacterial drug 3202
              tinidazole 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic molecule 19809
                              organic cyclic compound 19572
                                organic heterocyclic compound 18799
                                  heteroarene 16602
                                    monocyclic heteroarene 13592
                                      azole 12821
                                        diazole 8611
                                          imidazoles 7702
                                            tinidazole 2
paths to the root