Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:63627 term browser browse the term
Definition:1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.
Synonyms:exact_synonym: 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
 related_synonym: Formula=C8H13N3O4S;   InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3;   InChIKey=HJLSLZFTEKNLFI-UHFFFAOYSA-N;   SMILES=CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O;   timidazole
 alt_id: CHEBI:32227
 xref: DrugBank:DB00911;   Drug_Central:2671;   KEGG:D01426;   LINCS:LSM-5948
 xref_mesh: MESH:D014011
 xref: PMID:5458368;   Patent:US3376311;   Reaxys:618182;   Wikipedia:Tinidazole

show annotations for term's descendants           Sort by:
tinidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Tinidazole results in decreased activity of ABCB11 protein
Tinidazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 affects metabolic processing ISO CYP3A4 protein affects the metabolism of Tinidazole CTD PMID:12920490 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        antimicrobial agent 17374
          antimicrobial drug 6222
            antiprotozoal drug 3836
              tinidazole 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic molecule 19505
                              organic cyclic compound 19332
                                organic heterocyclic compound 18519
                                  heteroarene 16515
                                    monocyclic heteroarene 13362
                                      azole 12537
                                        diazole 8253
                                          imidazoles 7685
                                            tinidazole 2
paths to the root